Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:EIF4G2-C5orf45 (FusionGDB2 ID:26018)

Fusion Gene Summary for EIF4G2-C5orf45

Fusion gene summary

Fusion gene information	Fusion gene name: EIF4G2-C5orf45
	Fusion gene ID: 26018
		Hgene	Tgene
	Gene symbol	EIF4G2	C5orf45
	Gene ID	1982	51149
	Gene name	eukaryotic translation initiation factor 4 gamma 2	MRN complex interacting protein
	Synonyms	AAG1\|DAP5\|NAT1\|P97	C5orf45
	Cytomap	11p15.4	5q35.3
	Type of gene	protein-coding	protein-coding
	Description	eukaryotic translation initiation factor 4 gamma 2DAP-5aging-associated protein 1death-associated protein 5eIF-4-gamma 2eIF-4G 2eIF4G 2eukaryotic translation initiation factor 4G-like 1	MRN complex-interacting proteinMRN-interacting proteinUPF0544 protein C5orf45
	Modification date	20200313	20200313
	UniProtAcc	P78344	.
	Ensembl transtripts involved in fusion gene	ENST00000339995, ENST00000525681, ENST00000526148, ENST00000396525, ENST00000525995,	ENST00000292586, ENST00000521333, ENST00000523084, ENST00000518219, ENST00000523267, ENST00000403396, ENST00000376931, ENST00000518235, ENST00000520698,
Fusion gene scores	* DoF score	23 X 17 X 10=3910	5 X 4 X 3=60
	# samples	28	5
	** MAII score	log2(28/3910*10)=-3.80366987524975 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: EIF4G2 [Title/Abstract] AND C5orf45 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	EIF4G2(10818600)-C5orf45(179280437), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	EIF4G2	GO:0006446	regulation of translational initiation	11943866
Tgene	C5orf45	GO:0071168	protein localization to chromatin	27568553

Fusion gene breakpoints across EIF4G2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across C5orf45 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUAD	TCGA-78-7163-01A	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-

Top

Fusion Gene ORF analysis for EIF4G2-C5orf45

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000339995	ENST00000292586	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000339995	ENST00000521333	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000339995	ENST00000523084	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000525681	ENST00000292586	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000525681	ENST00000521333	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000525681	ENST00000523084	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000526148	ENST00000292586	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000526148	ENST00000521333	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-5UTR	ENST00000526148	ENST00000523084	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-intron	ENST00000339995	ENST00000518219	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-intron	ENST00000339995	ENST00000523267	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-intron	ENST00000525681	ENST00000518219	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-intron	ENST00000525681	ENST00000523267	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-intron	ENST00000526148	ENST00000518219	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
5CDS-intron	ENST00000526148	ENST00000523267	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000339995	ENST00000403396	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000525681	ENST00000376931	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000525681	ENST00000518235	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000525681	ENST00000520698	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000526148	ENST00000376931	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000526148	ENST00000403396	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000526148	ENST00000518235	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
Frame-shift	ENST00000526148	ENST00000520698	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
In-frame	ENST00000339995	ENST00000376931	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
In-frame	ENST00000339995	ENST00000518235	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
In-frame	ENST00000339995	ENST00000520698	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
In-frame	ENST00000525681	ENST00000403396	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000396525	ENST00000376931	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000396525	ENST00000403396	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000396525	ENST00000518235	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000396525	ENST00000520698	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000525995	ENST00000376931	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000525995	ENST00000403396	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000525995	ENST00000518235	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-3CDS	ENST00000525995	ENST00000520698	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-5UTR	ENST00000396525	ENST00000292586	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-5UTR	ENST00000396525	ENST00000521333	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-5UTR	ENST00000396525	ENST00000523084	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-5UTR	ENST00000525995	ENST00000292586	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-5UTR	ENST00000525995	ENST00000521333	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-5UTR	ENST00000525995	ENST00000523084	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-intron	ENST00000396525	ENST00000518219	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-intron	ENST00000396525	ENST00000523267	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-intron	ENST00000525995	ENST00000518219	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-
intron-intron	ENST00000525995	ENST00000523267	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000525681	EIF4G2	chr11	10818600	-	ENST00000403396	C5orf45	chr5	179280437	-	7100	3654	59	2890	943
ENST00000339995	EIF4G2	chr11	10818600	-	ENST00000518235	C5orf45	chr5	179280437	-	5146	3978	420	3215	931
ENST00000339995	EIF4G2	chr11	10818600	-	ENST00000520698	C5orf45	chr5	179280437	-	4813	3978	420	3215	931
ENST00000339995	EIF4G2	chr11	10818600	-	ENST00000376931	C5orf45	chr5	179280437	-	4904	3978	420	3215	931

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000525681	ENST00000403396	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-	0.003276698	0.99672335
ENST00000339995	ENST00000518235	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-	0.005445284	0.99455476
ENST00000339995	ENST00000520698	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-	0.005561203	0.99443877
ENST00000339995	ENST00000376931	EIF4G2	chr11	10818600	-	C5orf45	chr5	179280437	-	0.004040428	0.9959596

Top

Fusion Genomic Features for EIF4G2-C5orf45

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for EIF4G2-C5orf45

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:10818600/chr5:179280437)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
EIF4G2 P78344	.
FUNCTION: Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. {ECO:0000269\|PubMed:11511540, ECO:0000269\|PubMed:11943866, ECO:0000269\|PubMed:9032289, ECO:0000269\|PubMed:9049310}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

EIF4G2

chr11:10818600

chr5:179280437

ENST00000339995

543_666

1162

908.0

Domain

Hgene

EIF4G2

chr11:10818600

chr5:179280437

ENST00000339995

720_904

1162

908.0

Domain

Hgene

EIF4G2

chr11:10818600

chr5:179280437

ENST00000339995

78_308

1162

908.0

Domain

MIF4G

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Top

Fusion Gene Sequence for EIF4G2-C5orf45

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>26018_26018_1_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000339995_C5orf45_chr5_179280437_ENST00000376931_length(transcript)=4904nt_BP=3978nt
GCGCACTGCGGCGGGGCTGCGCCGCAACCGAGCTCAGCCCTGTGGCTCCTCCTCGCTGCCCTGCGCGGATTGGTGGCAGACGGCAACCGG
GCCGCTGATTGGGCGGCGAAGGAGCCATTCGGGGAGACTCTGGTGGGTTCGGCTGCCCCAAGAGTGATAAGTTCGGCTTCAGACACGCCT
TAGCGCCAGCAGTGAGTCGGAGCTCTATGGAGGTGGCAGCGGGTACCGAGTGGCGGCTGCAGCAGCGACTCCTCTGAGCTGAGTTTGAGG
CCGTCCCCGACTCCTTCCTCCCCCTTCCCTCCCCCTTTTTTTTGTTTTCCGTTCCCCTTTCCCCTCCCTTCCCTATCCCCGACGACCGGA
TCCTGAGGAGGCAGCTGCGGTGGCAGCTGCTGAGTTCTCGGTGAAGGTATTTCATTTCTCCTGTCCCCTCCCCTCCCCACCCCATCTATT
AATATTATTCTTTTGAAGATTCTTCGTTGTCAAGCCGCCAAAGTGGAGAGTGCGATTGCAGAAGGGGGTGCTTCTCGTTTCAGTGCTTCT
TCGGGCGGAGGAGGAAGTAGGGGTGCACCTCAGCACTATCCCAAGACTGCTGGCAACAGCGAGTTCCTGGGGAAAACCCCAGGGCAAAAC
GCTCAGAAATGGATTCCTGCACGAAGCACTAGACGAGATGACAACTCCGCAGCAAACAACTCCGCAAACGAAAAAGAACGACATGATGCA
ATCTTCAGGAAAGTAAGAGGCATACTAAATAAGCTTACTCCTGAAAAGTTTGACAAGCTATGCCTTGAGCTCCTCAATGTGGGTGTAGAG
TCTAAACTCATCCTTAAAGGGGTCATACTGCTGATTGTGGACAAAGCCCTAGAAGAGCCAAAGTATAGCTCACTGTATGCTCAGCTATGT
CTGCGATTGGCAGAAGATGCACCAAACTTTGATGGCCCAGCAGCAGAGGGTCAACCAGGACAGAAGCAAAGCACCACATTCAGACGCCTC
CTAATTTCCAAATTACAAGATGAATTTGAAAACCGAACTAGAAATGTTGATGTCTATGATAAGCGTGAAAATCCCCTCCTCCCCGAGGAG
GAGGAACAGAGAGCCATTGCTAAGATCAAGATGTTGGGAAACATCAAATTCATTGGAGAGCTTGGCAAGCTTGATCTTATTCACGAATCT
ATCCTTCATAAGTGCATCAAAACACTTTTGGAAAAGAAGAAGAGAGTCCAACTCAAAGATATGGGAGAGGATTTGGAGTGCCTCTGTCAG
ATAATGAGGACAGTGGGACCTAGATTAGACCATGAACGAGCCAAGTCCTTAATGGATCAGTACTTTGCCCGAATGTGCTCCTTGATGTTA
AGTAAGGAATTGCCAGCAAGGATTCGTTTCCTGCTGCAGGATACCGTAGAGTTGCGAGAACACCATTGGGTTCCTCGCAAGGCTTTTCTT
GACAATGGACCAAAGACGATCAATCAAATTCGTCAAGATGCAGTAAAAGATCTAGGGGTGTTTATTCCTGCTCCTATGGCTCAAGGGATG
AGAAGTGACTTCTTTCTGGAGGGACCGTTCATGCCACCCAGGATGAAAATGGATAGGGACCCACTTGGAGGACTTGCTGATATGTTTGGA
CAAATGCCAGGTAGCGGAATTGGTACTGGTCCAGGAGTTATCCAGGATAGATTTTCACCCACCATGGGACGTCATCGTTCAAATCAACTC
TTCAATGGCCATGGGGGACACATCATGCCTCCCACACAATCGCAGTTTGGAGAGATGGGAGGCAAGTTTATGAAAAGCCAGGGGCTAAGC
CAGCTCTACCATAACCAGAGTCAGGGACTCTTATCCCAGCTGCAAGGACAGTCGAAGGATATGCCACCTCGGTTTTCTAAGAAAGGACAG
CTTAATGCAGATGAGATTAGCCTGAGGCCTGCTCAGTCGTTCCTAATGAATAAAAATCAAGTGCCAAAGCTTCAGCCCCAGATAACTATG
ATTCCTCCTAGTGCACAACCACCACGCACTCAAACACCACCTCTGGGACAGACACCTCAGCTTGGTCTCAAAACTAATCCACCGCTTATC
CAGGAAAAGCCTGCCAAGACCAGCAAAAAGCCACCACCGTCAAAGGAAGAACTCCTTAAACTAACTGAAACTGTTGTGACTGAATATCTA
AATAGTGGAAATGCAAATGAGGCTGTCAATGGTGTAAGAGAAATGAGGGCTCCTAAACACTTTCTTCCTGAGATGTTAAGCAAAGTAATC
ATCCTGTCACTAGATAGAAGCGATGAAGATAAAGAAAAAGCAAGTTCTTTGATCAGTTTACTCAAACAGGAAGGGATAGCCACAAGTGAC
AACTTCATGCAGGCTTTCCTGAATGTATTGGACCAGTGTCCCAAACTGGAGGTTGACATCCCTTTGGTGAAATCCTATTTAGCACAGTTT
GCAGCTCGTGCCATCATTTCAGAGCTGGTGAGCATTTCAGAACTAGCTCAACCACTAGAAAGTGGCACCCATTTTCCTCTCTTCCTACTT
TGTCTTCAGCAGTTAGCTAAATTACAAGATCGAGAATGGTTAACAGAACTTTTTCAACAAAGCAAGGTCAATATGCAGAAAATGCTCCCA
GAAATTGATCAGAATAAGGACCGCATGTTGGAGATTTTGGAAGGAAAGGGACTGAGTTTCTTATTCCCACTCCTCAAATTGGAGAAGGAA
CTGTTGAAGCAAATAAAGTTGGATCCATCCCCTCAAACCATATATAAATGGATTAAAGATAACATCTCTCCCAAACTTCATGTAGATAAA
GGATTTGTGAACATCTTAATGACTAGCTTCTTACAGTACATTTCTAGTGAAGTAAACCCCCCCAGCGATGAAACAGATTCATCCTCTGCT
CCTTCCAAAGAACAGTTAGAGCAGGAAAAACAACTACTACTATCTTTCAAGCCAGTAATGCAGAAATTTCTTCATGATCACGTTGATCTA
CAAGTCAGTGCCCTGTATGCTCTCCAGGTGCACTGCTATAACAGCAACTTCCCAAAAGGCATGTTACTTCGCTTTTTTGTGCACTTCTAT
GACATGGAAATTATTGAAGAAGAAGCTTTCTTGGCTTGGAAAGAAGATATAACCCAAGAGTTTCCGGGAAAAGGCAAGGCTTTGTTCCAG
GTGAATCAGTGGCTAACCTGGTTAGAAACTGCTGAAGAAGAAGAATCAGAGGAAGAAGCTGACTAAAGAACCAGCCAAAGCCTTAAATTG
TGCAAAACATACTGTTGCTATGATGTAACTGCATTTGACCTAACCACTGCGAAAATTCATTCCGCTGTAATGTTTTCACAATATTTAAAG
CAGAAGCACGTCAGTTAGGATTTCCTTCTGCATAAGGTTTTTTTGTAGTGTAATGTCTTAATCATAGTCTACCATCAAATATTTTAGGAG
TATCTTTAATGTTTAGATAGTATATTAGCAGCATGCAATAATTACATCATAAGTTCTCAAGCAGAGGCAGTCTATTGCAAGGACCTTCTT
TGCTGCCAGTTATCATAGGCTGTTTTAAGTTAGAAAACTGAATAGCAACACTGAATACTGTAGAAATGCACTTTGCTCAGTAATACTTGA
GTTGTTGCAATATTTGATTATCCATTTGGTTGTTACAGAAAAATTCTTAACTGTAATTGATGGTTGTTGCCGTAATAGTATATTGCCTGT
ATTTCTACCTCTAGTAATGGGCTTTATGTGCTAGATTTTAATATCCTTGAGCCTGGGCAAGTGCACAAGTCTTTTTAAAAGAAACATGGT
TTACTTGCACAAAACTGATCAGTTTTGAGAGATCGTTAATGCCCTTGAAGTGGTTTTTGTGGGTGTGAAACAAATGGTGAGAATTTGAAT
TGGTCCCTCCTATTATAGTATTGAAATTAAGTCTACTTAATTTATCAAGTCATGTTCATGCCCTGATTTTATATACTTGTATCTATCAAT
AAACATTGTGATACTTGAGTAAAAAAGAGTGTCAAGTGGACATGCAAAGCTTGTGGAGAGAAGCAGTCCTTTTTGCAGGAAAAATCGCAG
CCCTCAGAGAGTCGCTGGCTGAAGTATCTAGAAAAGGACTCCCAAGAACTGGAGCTGGAAGGAACAGGAGTGTGTTTCAGCAAACAGCCT
TCATCCAAAATGGAGGAGCCAGGCCCCCGCTTCAGTCAAGACCTGCCTAGAAAAAGGAAGTGGAGCAGGAGCACCGTCCAGCCTCCGTGC
AGCCGTGGCGTGCAGGACTCGGGTGGCTCTGAGGTCGCCTGGGGACCCCAGAAGGGACAGGCTGGCCTGACATGGAAGGTGAAACAAGGC
AGCAGCCCCTGCCTCCAGGAGAACTCTGCAGACTGCAGTGCCGGGGAGCTGAGGGGTCCTGGGAAGGAGCTATGGAGTCCCATCCAGCAG
GTTACAGCCACATCCTCTAAATGGGCGCAATTTGTCCTGCCACCTAGAAAAAGTTCACATGTGGACAGTGAGCAGCCAAGGTCTCTTCAG
AGGGACCCCAGGCCAGCTGGTCCAGCACAGGCTAAGCAAGGGACCCCCAGAGCACAGGCCTCAAGAGAAGGCCTCAGCAGGCCCACTGCC
GCTGTCCAGCTTCCTCGGGCCACACACCCCGTCACATCTGGGTCTGAGAGGCCTTGCGGGAAGACCTCATGGGACGCAAGGACTCCCTGG
GCAGAGGGTGGGCCCCTGGTCCTGGAGGCACAGAATCCTCGACCCACACGACTATGTGACCTCTTTATAACTGGGGAAGACTTCGATGAT
GATGTGTGATCTGGGACTGGCAGGTTATTAATCGAGATACACTTGTTAGGAGGGACAGGGTTCCCCTAAGGCACTTTTAAAGATACTCTG

>26018_26018_1_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000339995_C5orf45_chr5_179280437_ENST00000376931_length(amino acids)=931AA_BP=
MSPPLPTPSINIILLKILRCQAAKVESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANN
SANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPG
QKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKD
MGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGV
FIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMG
GKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQ
LGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISL
LKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQ
SKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNP
PSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQE

--------------------------------------------------------------
>26018_26018_2_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000339995_C5orf45_chr5_179280437_ENST00000518235_length(transcript)=5146nt_BP=3978nt
GCGCACTGCGGCGGGGCTGCGCCGCAACCGAGCTCAGCCCTGTGGCTCCTCCTCGCTGCCCTGCGCGGATTGGTGGCAGACGGCAACCGG
GCCGCTGATTGGGCGGCGAAGGAGCCATTCGGGGAGACTCTGGTGGGTTCGGCTGCCCCAAGAGTGATAAGTTCGGCTTCAGACACGCCT
TAGCGCCAGCAGTGAGTCGGAGCTCTATGGAGGTGGCAGCGGGTACCGAGTGGCGGCTGCAGCAGCGACTCCTCTGAGCTGAGTTTGAGG
CCGTCCCCGACTCCTTCCTCCCCCTTCCCTCCCCCTTTTTTTTGTTTTCCGTTCCCCTTTCCCCTCCCTTCCCTATCCCCGACGACCGGA
TCCTGAGGAGGCAGCTGCGGTGGCAGCTGCTGAGTTCTCGGTGAAGGTATTTCATTTCTCCTGTCCCCTCCCCTCCCCACCCCATCTATT
AATATTATTCTTTTGAAGATTCTTCGTTGTCAAGCCGCCAAAGTGGAGAGTGCGATTGCAGAAGGGGGTGCTTCTCGTTTCAGTGCTTCT
TCGGGCGGAGGAGGAAGTAGGGGTGCACCTCAGCACTATCCCAAGACTGCTGGCAACAGCGAGTTCCTGGGGAAAACCCCAGGGCAAAAC
GCTCAGAAATGGATTCCTGCACGAAGCACTAGACGAGATGACAACTCCGCAGCAAACAACTCCGCAAACGAAAAAGAACGACATGATGCA
ATCTTCAGGAAAGTAAGAGGCATACTAAATAAGCTTACTCCTGAAAAGTTTGACAAGCTATGCCTTGAGCTCCTCAATGTGGGTGTAGAG
TCTAAACTCATCCTTAAAGGGGTCATACTGCTGATTGTGGACAAAGCCCTAGAAGAGCCAAAGTATAGCTCACTGTATGCTCAGCTATGT
CTGCGATTGGCAGAAGATGCACCAAACTTTGATGGCCCAGCAGCAGAGGGTCAACCAGGACAGAAGCAAAGCACCACATTCAGACGCCTC
CTAATTTCCAAATTACAAGATGAATTTGAAAACCGAACTAGAAATGTTGATGTCTATGATAAGCGTGAAAATCCCCTCCTCCCCGAGGAG
GAGGAACAGAGAGCCATTGCTAAGATCAAGATGTTGGGAAACATCAAATTCATTGGAGAGCTTGGCAAGCTTGATCTTATTCACGAATCT
ATCCTTCATAAGTGCATCAAAACACTTTTGGAAAAGAAGAAGAGAGTCCAACTCAAAGATATGGGAGAGGATTTGGAGTGCCTCTGTCAG
ATAATGAGGACAGTGGGACCTAGATTAGACCATGAACGAGCCAAGTCCTTAATGGATCAGTACTTTGCCCGAATGTGCTCCTTGATGTTA
AGTAAGGAATTGCCAGCAAGGATTCGTTTCCTGCTGCAGGATACCGTAGAGTTGCGAGAACACCATTGGGTTCCTCGCAAGGCTTTTCTT
GACAATGGACCAAAGACGATCAATCAAATTCGTCAAGATGCAGTAAAAGATCTAGGGGTGTTTATTCCTGCTCCTATGGCTCAAGGGATG
AGAAGTGACTTCTTTCTGGAGGGACCGTTCATGCCACCCAGGATGAAAATGGATAGGGACCCACTTGGAGGACTTGCTGATATGTTTGGA
CAAATGCCAGGTAGCGGAATTGGTACTGGTCCAGGAGTTATCCAGGATAGATTTTCACCCACCATGGGACGTCATCGTTCAAATCAACTC
TTCAATGGCCATGGGGGACACATCATGCCTCCCACACAATCGCAGTTTGGAGAGATGGGAGGCAAGTTTATGAAAAGCCAGGGGCTAAGC
CAGCTCTACCATAACCAGAGTCAGGGACTCTTATCCCAGCTGCAAGGACAGTCGAAGGATATGCCACCTCGGTTTTCTAAGAAAGGACAG
CTTAATGCAGATGAGATTAGCCTGAGGCCTGCTCAGTCGTTCCTAATGAATAAAAATCAAGTGCCAAAGCTTCAGCCCCAGATAACTATG
ATTCCTCCTAGTGCACAACCACCACGCACTCAAACACCACCTCTGGGACAGACACCTCAGCTTGGTCTCAAAACTAATCCACCGCTTATC
CAGGAAAAGCCTGCCAAGACCAGCAAAAAGCCACCACCGTCAAAGGAAGAACTCCTTAAACTAACTGAAACTGTTGTGACTGAATATCTA
AATAGTGGAAATGCAAATGAGGCTGTCAATGGTGTAAGAGAAATGAGGGCTCCTAAACACTTTCTTCCTGAGATGTTAAGCAAAGTAATC
ATCCTGTCACTAGATAGAAGCGATGAAGATAAAGAAAAAGCAAGTTCTTTGATCAGTTTACTCAAACAGGAAGGGATAGCCACAAGTGAC
AACTTCATGCAGGCTTTCCTGAATGTATTGGACCAGTGTCCCAAACTGGAGGTTGACATCCCTTTGGTGAAATCCTATTTAGCACAGTTT
GCAGCTCGTGCCATCATTTCAGAGCTGGTGAGCATTTCAGAACTAGCTCAACCACTAGAAAGTGGCACCCATTTTCCTCTCTTCCTACTT
TGTCTTCAGCAGTTAGCTAAATTACAAGATCGAGAATGGTTAACAGAACTTTTTCAACAAAGCAAGGTCAATATGCAGAAAATGCTCCCA
GAAATTGATCAGAATAAGGACCGCATGTTGGAGATTTTGGAAGGAAAGGGACTGAGTTTCTTATTCCCACTCCTCAAATTGGAGAAGGAA
CTGTTGAAGCAAATAAAGTTGGATCCATCCCCTCAAACCATATATAAATGGATTAAAGATAACATCTCTCCCAAACTTCATGTAGATAAA
GGATTTGTGAACATCTTAATGACTAGCTTCTTACAGTACATTTCTAGTGAAGTAAACCCCCCCAGCGATGAAACAGATTCATCCTCTGCT
CCTTCCAAAGAACAGTTAGAGCAGGAAAAACAACTACTACTATCTTTCAAGCCAGTAATGCAGAAATTTCTTCATGATCACGTTGATCTA
CAAGTCAGTGCCCTGTATGCTCTCCAGGTGCACTGCTATAACAGCAACTTCCCAAAAGGCATGTTACTTCGCTTTTTTGTGCACTTCTAT
GACATGGAAATTATTGAAGAAGAAGCTTTCTTGGCTTGGAAAGAAGATATAACCCAAGAGTTTCCGGGAAAAGGCAAGGCTTTGTTCCAG
GTGAATCAGTGGCTAACCTGGTTAGAAACTGCTGAAGAAGAAGAATCAGAGGAAGAAGCTGACTAAAGAACCAGCCAAAGCCTTAAATTG
TGCAAAACATACTGTTGCTATGATGTAACTGCATTTGACCTAACCACTGCGAAAATTCATTCCGCTGTAATGTTTTCACAATATTTAAAG
CAGAAGCACGTCAGTTAGGATTTCCTTCTGCATAAGGTTTTTTTGTAGTGTAATGTCTTAATCATAGTCTACCATCAAATATTTTAGGAG
TATCTTTAATGTTTAGATAGTATATTAGCAGCATGCAATAATTACATCATAAGTTCTCAAGCAGAGGCAGTCTATTGCAAGGACCTTCTT
TGCTGCCAGTTATCATAGGCTGTTTTAAGTTAGAAAACTGAATAGCAACACTGAATACTGTAGAAATGCACTTTGCTCAGTAATACTTGA
GTTGTTGCAATATTTGATTATCCATTTGGTTGTTACAGAAAAATTCTTAACTGTAATTGATGGTTGTTGCCGTAATAGTATATTGCCTGT
ATTTCTACCTCTAGTAATGGGCTTTATGTGCTAGATTTTAATATCCTTGAGCCTGGGCAAGTGCACAAGTCTTTTTAAAAGAAACATGGT
TTACTTGCACAAAACTGATCAGTTTTGAGAGATCGTTAATGCCCTTGAAGTGGTTTTTGTGGGTGTGAAACAAATGGTGAGAATTTGAAT
TGGTCCCTCCTATTATAGTATTGAAATTAAGTCTACTTAATTTATCAAGTCATGTTCATGCCCTGATTTTATATACTTGTATCTATCAAT
AAACATTGTGATACTTGAGTAAAAAAGAGTGTCAAGTGGACATGCAAAGCTTGTGGAGAGAAGCAGTCCTTTTTGCAGGCTTATGGTGAA
GGCTCTGGTGCTGATTGTAGACGCCATGTCCAAAAGTTAAATCTACTACAGGGACAAGTTTCAGAGCTGCCACTCAGGTCTCTAGAAGAA
ACTGTCAGTGCCAGTGAAGAAGAAAACGTGGGACACCAGCAGGCTGGGAATGTGAAGCAGCAGGAAAAATCGCAGCCCTCAGAGAGTCGC
TGGCTGAAGTATCTAGAAAAGGACTCCCAAGAACTGGAGCTGGAAGGAACAGGAGTGTGTTTCAGCAAACAGCCTTCATCCAAAATGGAG
GAGCCAGGCCCCCGCTTCAGTCAAGACCTGCCTAGAAAAAGGAAGTGGAGCAGGAGCACCGTCCAGCCTCCGTGCAGCCGTGGCGTGCAG
GACTCGGGTGGCTCTGAGGTCGCCTGGGGACCCCAGAAGGGACAGGCTGGCCTGACATGGAAGGTGAAACAAGGCAGCAGCCCCTGCCTC
CAGGAGAACTCTGCAGACTGCAGTGCCGGGGAGCTGAGGGGTCCTGGGAAGGAGCTATGGAGTCCCATCCAGCAGGATGGCTACAAAGAG
ATCTTATTTTAAAAGCAGCTGATGGTTTGGAAATGAGAGAACTACAGTGGTGAAGAGACCAGGAGGCAGCTCTCAGTGAAACCAACATTG
CGGATGCCCTTCGTGAGCCTTCTCAGTCCCAGCAGGAAGCCCACAACACTGGCCTCCCCAGCCTGCCTGCTGACAACACCTAGGCTTACT
TTATCTAAAATCAGAGTGTACCAGGTCTGTAGCAGAAAATAATCAACTAAATGTCAGGGACCTATGAGTCATTTAAAACAAAAGAGAAAG
TGAAAGCCATTAGGCAAGCTATGTGCTGGGCTGCTAACGTAGCCCCTGCAGGGAGGGGTCAGGAGCGCGCTGCAGTGAGCCTTGGGTCTC
GCAGGCCCAGCCCTGCTGCAAGGAGCCAGGGCACCCAGGAAACATCAGCACACACACACACAGGGACCCTCCCTTCATGTCACTTGTTTT
GCTGCCCTAAATGGCTTCTTGCACCCTAACCCCTGATCCTGGAAGAAGGCAGAGAAACTGGCCCGTACAGAGACCTGCAATTCTACGCAA

>26018_26018_2_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000339995_C5orf45_chr5_179280437_ENST00000518235_length(amino acids)=931AA_BP=
MSPPLPTPSINIILLKILRCQAAKVESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANN
SANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPG
QKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKD
MGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGV
FIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMG
GKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQ
LGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISL
LKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQ
SKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNP
PSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQE

--------------------------------------------------------------
>26018_26018_3_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000339995_C5orf45_chr5_179280437_ENST00000520698_length(transcript)=4813nt_BP=3978nt
GCGCACTGCGGCGGGGCTGCGCCGCAACCGAGCTCAGCCCTGTGGCTCCTCCTCGCTGCCCTGCGCGGATTGGTGGCAGACGGCAACCGG
GCCGCTGATTGGGCGGCGAAGGAGCCATTCGGGGAGACTCTGGTGGGTTCGGCTGCCCCAAGAGTGATAAGTTCGGCTTCAGACACGCCT
TAGCGCCAGCAGTGAGTCGGAGCTCTATGGAGGTGGCAGCGGGTACCGAGTGGCGGCTGCAGCAGCGACTCCTCTGAGCTGAGTTTGAGG
CCGTCCCCGACTCCTTCCTCCCCCTTCCCTCCCCCTTTTTTTTGTTTTCCGTTCCCCTTTCCCCTCCCTTCCCTATCCCCGACGACCGGA
TCCTGAGGAGGCAGCTGCGGTGGCAGCTGCTGAGTTCTCGGTGAAGGTATTTCATTTCTCCTGTCCCCTCCCCTCCCCACCCCATCTATT
AATATTATTCTTTTGAAGATTCTTCGTTGTCAAGCCGCCAAAGTGGAGAGTGCGATTGCAGAAGGGGGTGCTTCTCGTTTCAGTGCTTCT
TCGGGCGGAGGAGGAAGTAGGGGTGCACCTCAGCACTATCCCAAGACTGCTGGCAACAGCGAGTTCCTGGGGAAAACCCCAGGGCAAAAC
GCTCAGAAATGGATTCCTGCACGAAGCACTAGACGAGATGACAACTCCGCAGCAAACAACTCCGCAAACGAAAAAGAACGACATGATGCA
ATCTTCAGGAAAGTAAGAGGCATACTAAATAAGCTTACTCCTGAAAAGTTTGACAAGCTATGCCTTGAGCTCCTCAATGTGGGTGTAGAG
TCTAAACTCATCCTTAAAGGGGTCATACTGCTGATTGTGGACAAAGCCCTAGAAGAGCCAAAGTATAGCTCACTGTATGCTCAGCTATGT
CTGCGATTGGCAGAAGATGCACCAAACTTTGATGGCCCAGCAGCAGAGGGTCAACCAGGACAGAAGCAAAGCACCACATTCAGACGCCTC
CTAATTTCCAAATTACAAGATGAATTTGAAAACCGAACTAGAAATGTTGATGTCTATGATAAGCGTGAAAATCCCCTCCTCCCCGAGGAG
GAGGAACAGAGAGCCATTGCTAAGATCAAGATGTTGGGAAACATCAAATTCATTGGAGAGCTTGGCAAGCTTGATCTTATTCACGAATCT
ATCCTTCATAAGTGCATCAAAACACTTTTGGAAAAGAAGAAGAGAGTCCAACTCAAAGATATGGGAGAGGATTTGGAGTGCCTCTGTCAG
ATAATGAGGACAGTGGGACCTAGATTAGACCATGAACGAGCCAAGTCCTTAATGGATCAGTACTTTGCCCGAATGTGCTCCTTGATGTTA
AGTAAGGAATTGCCAGCAAGGATTCGTTTCCTGCTGCAGGATACCGTAGAGTTGCGAGAACACCATTGGGTTCCTCGCAAGGCTTTTCTT
GACAATGGACCAAAGACGATCAATCAAATTCGTCAAGATGCAGTAAAAGATCTAGGGGTGTTTATTCCTGCTCCTATGGCTCAAGGGATG
AGAAGTGACTTCTTTCTGGAGGGACCGTTCATGCCACCCAGGATGAAAATGGATAGGGACCCACTTGGAGGACTTGCTGATATGTTTGGA
CAAATGCCAGGTAGCGGAATTGGTACTGGTCCAGGAGTTATCCAGGATAGATTTTCACCCACCATGGGACGTCATCGTTCAAATCAACTC
TTCAATGGCCATGGGGGACACATCATGCCTCCCACACAATCGCAGTTTGGAGAGATGGGAGGCAAGTTTATGAAAAGCCAGGGGCTAAGC
CAGCTCTACCATAACCAGAGTCAGGGACTCTTATCCCAGCTGCAAGGACAGTCGAAGGATATGCCACCTCGGTTTTCTAAGAAAGGACAG
CTTAATGCAGATGAGATTAGCCTGAGGCCTGCTCAGTCGTTCCTAATGAATAAAAATCAAGTGCCAAAGCTTCAGCCCCAGATAACTATG
ATTCCTCCTAGTGCACAACCACCACGCACTCAAACACCACCTCTGGGACAGACACCTCAGCTTGGTCTCAAAACTAATCCACCGCTTATC
CAGGAAAAGCCTGCCAAGACCAGCAAAAAGCCACCACCGTCAAAGGAAGAACTCCTTAAACTAACTGAAACTGTTGTGACTGAATATCTA
AATAGTGGAAATGCAAATGAGGCTGTCAATGGTGTAAGAGAAATGAGGGCTCCTAAACACTTTCTTCCTGAGATGTTAAGCAAAGTAATC
ATCCTGTCACTAGATAGAAGCGATGAAGATAAAGAAAAAGCAAGTTCTTTGATCAGTTTACTCAAACAGGAAGGGATAGCCACAAGTGAC
AACTTCATGCAGGCTTTCCTGAATGTATTGGACCAGTGTCCCAAACTGGAGGTTGACATCCCTTTGGTGAAATCCTATTTAGCACAGTTT
GCAGCTCGTGCCATCATTTCAGAGCTGGTGAGCATTTCAGAACTAGCTCAACCACTAGAAAGTGGCACCCATTTTCCTCTCTTCCTACTT
TGTCTTCAGCAGTTAGCTAAATTACAAGATCGAGAATGGTTAACAGAACTTTTTCAACAAAGCAAGGTCAATATGCAGAAAATGCTCCCA
GAAATTGATCAGAATAAGGACCGCATGTTGGAGATTTTGGAAGGAAAGGGACTGAGTTTCTTATTCCCACTCCTCAAATTGGAGAAGGAA
CTGTTGAAGCAAATAAAGTTGGATCCATCCCCTCAAACCATATATAAATGGATTAAAGATAACATCTCTCCCAAACTTCATGTAGATAAA
GGATTTGTGAACATCTTAATGACTAGCTTCTTACAGTACATTTCTAGTGAAGTAAACCCCCCCAGCGATGAAACAGATTCATCCTCTGCT
CCTTCCAAAGAACAGTTAGAGCAGGAAAAACAACTACTACTATCTTTCAAGCCAGTAATGCAGAAATTTCTTCATGATCACGTTGATCTA
CAAGTCAGTGCCCTGTATGCTCTCCAGGTGCACTGCTATAACAGCAACTTCCCAAAAGGCATGTTACTTCGCTTTTTTGTGCACTTCTAT
GACATGGAAATTATTGAAGAAGAAGCTTTCTTGGCTTGGAAAGAAGATATAACCCAAGAGTTTCCGGGAAAAGGCAAGGCTTTGTTCCAG
GTGAATCAGTGGCTAACCTGGTTAGAAACTGCTGAAGAAGAAGAATCAGAGGAAGAAGCTGACTAAAGAACCAGCCAAAGCCTTAAATTG
TGCAAAACATACTGTTGCTATGATGTAACTGCATTTGACCTAACCACTGCGAAAATTCATTCCGCTGTAATGTTTTCACAATATTTAAAG
CAGAAGCACGTCAGTTAGGATTTCCTTCTGCATAAGGTTTTTTTGTAGTGTAATGTCTTAATCATAGTCTACCATCAAATATTTTAGGAG
TATCTTTAATGTTTAGATAGTATATTAGCAGCATGCAATAATTACATCATAAGTTCTCAAGCAGAGGCAGTCTATTGCAAGGACCTTCTT
TGCTGCCAGTTATCATAGGCTGTTTTAAGTTAGAAAACTGAATAGCAACACTGAATACTGTAGAAATGCACTTTGCTCAGTAATACTTGA
GTTGTTGCAATATTTGATTATCCATTTGGTTGTTACAGAAAAATTCTTAACTGTAATTGATGGTTGTTGCCGTAATAGTATATTGCCTGT
ATTTCTACCTCTAGTAATGGGCTTTATGTGCTAGATTTTAATATCCTTGAGCCTGGGCAAGTGCACAAGTCTTTTTAAAAGAAACATGGT
TTACTTGCACAAAACTGATCAGTTTTGAGAGATCGTTAATGCCCTTGAAGTGGTTTTTGTGGGTGTGAAACAAATGGTGAGAATTTGAAT
TGGTCCCTCCTATTATAGTATTGAAATTAAGTCTACTTAATTTATCAAGTCATGTTCATGCCCTGATTTTATATACTTGTATCTATCAAT
AAACATTGTGATACTTGAGTAAAAAAGAGTGTCAAGTGGACATGCAAAGCTTGTGGAGAGAAGCAGTCCTTTTTGCAGGAAAAATCGCAG
CCCTCAGAGAGTCGCTGGCTGAAGTATCTAGAAAAGGACTCCCAAGAACTGGAGCTGGAAGGAACAGGAGTGTGTTTCAGCAAACAGCCT
TCATCCAAAATGGAGGAGCCAGGCCCCCGCTTCAGTCAAGACCTGCCTAGAAAAAGGAAGTGGAGCAGGAGCACCGTCCAGCCTCCGTGC
AGCCGTGGCGTGCAGGACTCGGGTGGCTCTGAGGTCGCCTGGGGACCCCAGAAGGGACAGGCTGGCCTGACATGGAAGGTGAAACAAGGC
AGCAGCCCCTGCCTCCAGGAGAACTCTGCAGACTGCAGTGCCGGGGAGCTGAGGGGTCCTGGGAAGGAGCTATGGAGTCCCATCCAGCAG
GATGGCTACAAAGAGATCTTATTTTAAAAGCAGCTGATGGTTTGGAAATGAGAGAACTACAGTGGTGAAGAGACCAGGAGGCAGCTCTCA
GTGAAACCAACATTGCGGATGCCCTTCGTGAGCCTTCTCAGTCCCAGCAGGAAGCCCACAACACTGGCCTCCCCAGCCTGCCTGCTGACA
ACACCTAGGCTTACTTTATCTAAAATCAGAGTGTACCAGGTCTGTAGCAGAAAATAATCAACTAAATGTCAGGGACCTATGAGTCATTTA
AAACAAAAGAGAAAGTGAAAGCCATTAGGCAAGCTATGTGCTGGGCTGCTAACGTAGCCCCTGCAGGGAGGGGTCAGGAGCGCGCTGCAG

>26018_26018_3_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000339995_C5orf45_chr5_179280437_ENST00000520698_length(amino acids)=931AA_BP=
MSPPLPTPSINIILLKILRCQAAKVESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANN
SANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPG
QKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKD
MGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGV
FIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMG
GKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQ
LGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISL
LKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQ
SKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNP
PSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQE

--------------------------------------------------------------
>26018_26018_4_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000525681_C5orf45_chr5_179280437_ENST00000403396_length(transcript)=7100nt_BP=3654nt
CTGAAATACGTTGTAATTGAATGAAGGCTTATAGATCTGTATGTTAGCAGTGTCTAATTTTGGTGCTCTTTCTCGTTCCAGGTATTTCAT
TTCTCCTGTCCCCTCCCCTCCCCACCCCATCTATTAATATTATTCTTTTGAAGATTCTTCGTTGTCAAGCCGCCAAAGTGGAGAGTGCGA
TTGCAGAAGGGGGTGCTTCTCGTTTCAGTGCTTCTTCGGGCGGAGGAGGAAGTAGGGGTGCACCTCAGCACTATCCCAAGACTGCTGGCA
ACAGCGAGTTCCTGGGGAAAACCCCAGGGCAAAACGCTCAGAAATGGATTCCTGCACGAAGCACTAGACGAGATGACAACTCCGCAGCAA
ACAACTCCGCAAACGAAAAAGAACGACATGATGCAATCTTCAGGAAAGTAAGAGGCATACTAAATAAGCTTACTCCTGAAAAGTTTGACA
AGCTATGCCTTGAGCTCCTCAATGTGGGTGTAGAGTCTAAACTCATCCTTAAAGGGGTCATACTGCTGATTGTGGACAAAGCCCTAGAAG
AGCCAAAGTATAGCTCACTGTATGCTCAGCTATGTCTGCGATTGGCAGAAGATGCACCAAACTTTGATGGCCCAGCAGCAGAGGGTCAAC
CAGGACAGAAGCAAAGCACCACATTCAGACGCCTCCTAATTTCCAAATTACAAGATGAATTTGAAAACCGAACTAGAAATGTTGATGTCT
ATGATAAGCGTGAAAATCCCCTCCTCCCCGAGGAGGAGGAACAGAGAGCCATTGCTAAGATCAAGATGTTGGGAAACATCAAATTCATTG
GAGAGCTTGGCAAGCTTGATCTTATTCACGAATCTATCCTTCATAAGTGCATCAAAACACTTTTGGAAAAGAAGAAGAGAGTCCAACTCA
AAGATATGGGAGAGGATTTGGAGTGCCTCTGTCAGATAATGAGGACAGTGGGACCTAGATTAGACCATGAACGAGCCAAGTCCTTAATGG
ATCAGTACTTTGCCCGAATGTGCTCCTTGATGTTAAGTAAGGAATTGCCAGCAAGGATTCGTTTCCTGCTGCAGGATACCGTAGAGTTGC
GAGAACACCATTGGGTTCCTCGCAAGGCTTTTCTTGACAATGGACCAAAGACGATCAATCAAATTCGTCAAGATGCAGTAAAAGATCTAG
GGGTGTTTATTCCTGCTCCTATGGCTCAAGGGATGAGAAGTGACTTCTTTCTGGAGGGACCGTTCATGCCACCCAGGATGAAAATGGATA
GGGACCCACTTGGAGGACTTGCTGATATGTTTGGACAAATGCCAGGTAGCGGAATTGGTACTGGTCCAGGAGTTATCCAGGATAGATTTT
CACCCACCATGGGACGTCATCGTTCAAATCAACTCTTCAATGGCCATGGGGGACACATCATGCCTCCCACACAATCGCAGTTTGGAGAGA
TGGGAGGCAAGTTTATGAAAAGCCAGGGGCTAAGCCAGCTCTACCATAACCAGAGTCAGGGACTCTTATCCCAGCTGCAAGGACAGTCGA
AGGATATGCCACCTCGGTTTTCTAAGAAAGGACAGCTTAATGCAGATGAGATTAGCCTGAGGCCTGCTCAGTCGTTCCTAATGAATAAAA
ATCAAGTGCCAAAGCTTCAGCCCCAGATAACTATGATTCCTCCTAGTGCACAACCACCACGCACTCAAACACCACCTCTGGGACAGACAC
CTCAGCTTGGTCTCAAAACTAATCCACCGCTTATCCAGGAAAAGCCTGCCAAGACCAGCAAAAAGCCACCACCGTCAAAGGAAGAACTCC
TTAAACTAACTGAAACTGTTGTGACTGAATATCTAAATAGTGGAAATGCAAATGAGGCTGTCAATGGTGTAAGAGAAATGAGGGCTCCTA
AACACTTTCTTCCTGAGATGTTAAGCAAAGTAATCATCCTGTCACTAGATAGAAGCGATGAAGATAAAGAAAAAGCAAGTTCTTTGATCA
GTTTACTCAAACAGGAAGGGATAGCCACAAGTGACAACTTCATGCAGGCTTTCCTGAATGTATTGGACCAGTGTCCCAAACTGGAGGTTG
ACATCCCTTTGGTGAAATCCTATTTAGCACAGTTTGCAGCTCGTGCCATCATTTCAGAGCTGGTGAGCATTTCAGAACTAGCTCAACCAC
TAGAAAGTGGCACCCATTTTCCTCTCTTCCTACTTTGTCTTCAGCAGTTAGCTAAATTACAAGATCGAGAATGGTTAACAGAACTTTTTC
AACAAAGCAAGGTCAATATGCAGAAAATGCTCCCAGAAATTGATCAGAATAAGGACCGCATGTTGGAGATTTTGGAAGGAAAGGGACTGA
GTTTCTTATTCCCACTCCTCAAATTGGAGAAGGAACTGTTGAAGCAAATAAAGTTGGATCCATCCCCTCAAACCATATATAAATGGATTA
AAGATAACATCTCTCCCAAACTTCATGTAGATAAAGGATTTGTGAACATCTTAATGACTAGCTTCTTACAGTACATTTCTAGTGAAGTAA
ACCCCCCCAGCGATGAAACAGATTCATCCTCTGCTCCTTCCAAAGAACAGTTAGAGCAGGAAAAACAACTACTACTATCTTTCAAGCCAG
TAATGCAGAAATTTCTTCATGATCACGTTGATCTACAAGTCAGTGCCCTGTATGCTCTCCAGGTGCACTGCTATAACAGCAACTTCCCAA
AAGGCATGTTACTTCGCTTTTTTGTGCACTTCTATGACATGGAAATTATTGAAGAAGAAGCTTTCTTGGCTTGGAAAGAAGATATAACCC
AAGAGTTTCCGGGAAAAGGCAAGGCTTTGTTCCAGGTGAATCAGTGGCTAACCTGGTTAGAAACTGCTGAAGAAGAAGAATCAGAGGAAG
AAGCTGACTAAAGAACCAGCCAAAGCCTTAAATTGTGCAAAACATACTGTTGCTATGATGTAACTGCATTTGACCTAACCACTGCGAAAA
TTCATTCCGCTGTAATGTTTTCACAATATTTAAAGCAGAAGCACGTCAGTTAGGATTTCCTTCTGCATAAGGTTTTTTTGTAGTGTAATG
TCTTAATCATAGTCTACCATCAAATATTTTAGGAGTATCTTTAATGTTTAGATAGTATATTAGCAGCATGCAATAATTACATCATAAGTT
CTCAAGCAGAGGCAGTCTATTGCAAGGACCTTCTTTGCTGCCAGTTATCATAGGCTGTTTTAAGTTAGAAAACTGAATAGCAACACTGAA
TACTGTAGAAATGCACTTTGCTCAGTAATACTTGAGTTGTTGCAATATTTGATTATCCATTTGGTTGTTACAGAAAAATTCTTAACTGTA
ATTGATGGTTGTTGCCGTAATAGTATATTGCCTGTATTTCTACCTCTAGTAATGGGCTTTATGTGCTAGATTTTAATATCCTTGAGCCTG
GGCAAGTGCACAAGTCTTTTTAAAAGAAACATGGTTTACTTGCACAAAACTGATCAGTTTTGAGAGATCGTTAATGCCCTTGAAGTGGTT
TTTGTGGGTGTGAAACAAATGGTGAGAATTTGAATTGGTCCCTCCTATTATAGTATTGAAATTAAGTCTACTTAATTTATCAAGTCATGT
TCATGCCCTGATTTTATATACTTGTATCTATCAATAAACATTGTGATACTTGATGTAAAAAAGAGTGTCAAGTGGACATGCAAAGCTTGT
GGAGAGAAGCAGTCCTTTTTGCAGAGTTCCCCAGACACGGAGCTCCTGCTTCCGAGCTTCCTGTTCCTTCAGGAAGTGAAATGGATGGAG
CAGAATCTGGAAAGGCTTATGGTGAAGGCTCTGGTGCTGATTGTAGACGCCATGTCCAAAAGTTAAATCTACTACAGGGACAAGTTTCAG
AGCTGCCACTCAGGTCTCTAGAAGAAACTGTCAGTGCCAGTGAAGAAGAAAACGTGGGACACCAGCAGGCTGGGAATGTGAAGCAGCAGG
AAAAATCGCAGCCCTCAGAGAGTCGCTGGCTGAAGTATCTAGAAAAGGACTCCCAAGAACTGGAGCTGGAAGGAACAGGAGTGTGTTTCA
GCAAACAGCCTTCATCCAAAATGGAGGAGCCAGGCCCCCGCTTCAGTCAAGACCTGCCTAGAAAAAGGAAGTGGAGCAGGAGCACCGTCC
AGCCTCCGTGCAGCCGTGGCGTGCAGGACTCGGGTGGCTCTGAGGTCGCCTGGGGACCCCAGAAGGGACAGGCTGGCCTGACATGGAAGG
TGAAACAAGGCAGCAGCCCCTGCCTCCAGGAGAACTCTGCAGACTGCAGTGCCGGGGAGCTGAGGGGTCCTGGGAAGGAGCTATGGAGTC
CCATCCAGCAGGATGGCTACAAAGAGATCTTATTTTAAAAGCAGCTGATGGTTTGGAAATGAGAGAACTACAGTGGTGAAGAGACCAGGA
GGCAGCTCTCAGTGAAACCAACATTGCGGATGCCCTTCGTGAGCCTTCTCAGTCCCAGCAGGAAGCCCACAACACTGGCCTCCCCAGCCT
GCCTGCTGACAACACCTAGGCTTACTTTATCTAAAATCAGAGTGTACCAGGTCTGTAGCAGAAAATAATCAACTAAATGTCAGGGACCTA
TGAGTCATTTAAAACAAAAGAGAAAGTGAAAGCCATTAGGCAAGCTATGTGCTGGGCTGCTAACGTAGCCCCTGCAGGGAGGGGTCAGGA
GCGCGCTGCAGTGAGCCTTGGGTCTCGCAGGCCCAGCCCTGCTGCAAGGAGCCAGGGCACCCAGGAAACATCAGCACACACACACACAGG
GACCCTCCCTTCATGTCACTTGTTTTGCTGCCCTAAATGGCTTCTTGCACCCTAACCCCTGATCCTGGAAGAAGGCAGAGAAACTGGCCC
GTACAGAGACCTGCAATTCTACGCAAGCTTAACACAACTATGAGACAGAAGAGGGGCACGCAGAAGAGGTGGGCAAAAGTGGTCACAACG
GCGGGGGATGCTTTGAATACTGGATGGTGTCCAGAGCCGCTCCGATGTCATAGTTCTTGGTCTGCAGGAGCCTGGTGAGCCAGCCGCCTT
CATCAGAGAAGCCCATGGACAGCATCTGGGAGAGGGACTCAATCAGCCGCGGGTCAGCCTCTGCCGAAACAGTAAGGAAGCCATGAGGAG
TGGTGCTGAGCCCTGTGAGTGACCCGAAACACATACCCTGCTGCCTTGGCCAGCCAGGACCAGGGTCTGCCAGTGTCCGAGCCTGCCCAG
AGCTCTCGTCCTCACAGGCCACAGTGGACCTGCTTTCCCTGTAAAGGGCCAAGCAGTCTTTTTCACACTGCTCAACTCTGCCACTGCGAC
ACCAGGCAGCCAGGTGGTGTGTAAGCAGAACCATCAATGGACACTGAAATAGGCATTTCACCTGTCACATCTTTTGATTTTAAAATGTAA
GAACAGGCCAGTTAGCCAATTATTACACTCCTCCATGCAAGAGATGATGGGGCATTGAAATAGATTGAAGATGGAGAGAGATGAATGGAT
ACAAGATACATTTTGGAGGTAGAATGAACAGGACTTGGAAATGTATGTGGAGAAGGCAAAGGAGTTAAAGATGATATCTGGAGCAGCACA
ACTCACAATTGCAAAGATGTGGAACCAACCTAACTGCCCATCAAGCAATGAGTGGATAAAGAAAATGTGGTATATATACACCATGGAATA
CTACTCAGCCACAAAAAGGAACGAAATAATACCTTTTGCAGCAACTTGGACGGAGCTGGAGGCCATTATCCTAAGTAAAGTAATTCAGGA
ATGGATACCAAATATCATATGTTCTCACTTATGAGTAGATGCTAAGCTATGATGATGCAAAGACATAAGAATGATATAGCTTTCCCTCTC
CCTCTTTCTCCACGGTCTCCCTCTGATGCCGAGCCAAAGCTGGACTGTACTGCTGCCATCTCGGCTCACTGCAACCTCCCTGCCTGATTC
TCTTGCCTCAGCCTGCCGAGTGCCTGCGATTGCAGGTGCGCGCCGCCACGACTGACTGGTTTTCGTGTTTTTTTGGTGGAGACGGGGTTT
CGCTGTGTTGGCCGGGCTGGTCTCCAGCTCCTAACCACGAGTGATCCGCCAGCCTCGGCCTCCCGAGGTGCCGGGATTGCAGACGGAGTC
TGGTTCACTCAGTGCTCAATGGTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCGCTACAACCTCCACCTCCCAGCTGCCTGCCTT
AGCCTCCCAAAGTGCCGAGATTGCAGCCTCTGCCCGGCCGCCACCCCGTCTGGGAAGTGAGGAGCGTCTCTGCCTGGCCGCCCATCGTCT
GGAATGTGAGGAGCCCCTCTGCCTGGCTGCCCAGTCTGGAAAGTGAGGAGCGTCTCTGCCCGGCCACCCATCGTCTGAGATGTGGGGAGC
GCCTCTGCCCCGCCGCCCTGTCTGGGATGTGAGGAGCGCCTCTGCCTGGCCGCGACCCCATCCGGGAGGTGAGGAGCGTCTCTGCCCGGC
CGCCCCGTCTGAGAAGTGAGGAGACCCTCCGCCCGGCAGCCACCCCGTCCGGGATGTGAGGGGCGCCTCTGCCCGGCCGCCCCTACTGGG
AAGTGAGGAGCCCCTCTGCCCGGCCACCACCCCGTCTGGGAGGTGTACCCAACAGCTCATTGAGAACGGGCCATGATGACAATGGCGGCT
TTGTGGAATAGAAAGCGGGGAAAGGTGGGGAAAAGATTGAGAAATCGGATGGTTGCCGTGTCTGTGTGGAAAGAAGTAGACATGGGAGAC
TTTTCATTTTGTTCTGTACTAAGAAAAATTCTTATCCTGTTGATCTGTGACCTTACCCCCAACCCCGTGCTCTCTGAAACATGTGCTGTG
TCCACTCAGGGTTAAATGGATTAAGGGCGGTGCAAGATGTGCTTTGTTAAACAGATGCTTGAAGGCAGCATGCTCCTTAAGAGTCATCAC
CACTCCCTAATCTCAAGTACCCAGGGACACAAACGCTGCGGAAGGCCGCAGGGTCCTCTGCCTAGGAAAACCAGAGACCTTTGTTCACTT

>26018_26018_4_EIF4G2-C5orf45_EIF4G2_chr11_10818600_ENST00000525681_C5orf45_chr5_179280437_ENST00000403396_length(amino acids)=943AA_BP=
MVLFLVPGISFLLSPPLPTPSINIILLKILRCQAAKVESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPAR
STRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAP
NFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKT
LLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTIN
QIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHI
MPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPP
RTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSD
EDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKL
QDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMT
SFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for EIF4G2-C5orf45

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for EIF4G2-C5orf45

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for EIF4G2-C5orf45

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source