Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ELAC2-COX10 (FusionGDB2 ID:26124)

Fusion Gene Summary for ELAC2-COX10

Fusion gene summary

Fusion gene information	Fusion gene name: ELAC2-COX10
	Fusion gene ID: 26124
		Hgene	Tgene
	Gene symbol	ELAC2	COX10
	Gene ID	60528	1352
	Gene name	elaC ribonuclease Z 2	cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
	Synonyms	COXPD17\|ELC2\|HPC2	-
	Cytomap	17p12	17p12
	Type of gene	protein-coding	protein-coding
	Description	zinc phosphodiesterase ELAC protein 2RNase Z 2elaC homolog 2elaC homolog protein 2elaC-like protein 2heredity prostate cancer protein 2putative prostate cancer susceptibility protein HPC2/ELAC2ribonuclease Z 2tRNA 3 endonuclease 2tRNase Z (long f	protoheme IX farnesyltransferase, mitochondrialCOX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferaseCOX10, heme A:farnesyltransferase cytochrome c oxidase assembly factorcytochrome c oxidase assembly homolog 10cytochrome c
	Modification date	20200315	20200313
	UniProtAcc	Q9BQ52	Q12887
	Ensembl transtripts involved in fusion gene	ENST00000338034, ENST00000395962, ENST00000426905, ENST00000578071, ENST00000609345,	ENST00000537334, ENST00000429152, ENST00000261643, ENST00000536205,
Fusion gene scores	* DoF score	4 X 6 X 4=96	2 X 3 X 2=12
	# samples	5	3
	** MAII score	log2(5/96*10)=-0.941106310946431 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: ELAC2 [Title/Abstract] AND COX10 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ELAC2(12919085)-COX10(14063194), # samples:3
Anticipated loss of major functional domain due to fusion event.	ELAC2-COX10 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. ELAC2-COX10 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ELAC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across COX10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-HC-7213-01A	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
ChimerDB4	PRAD	TCGA-HC-7213	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
ChimerDB4	PRAD	TCGA-HC-7213	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+

Top

Fusion Gene ORF analysis for ELAC2-COX10

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000338034	ENST00000537334	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-5UTR	ENST00000338034	ENST00000537334	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5CDS-5UTR	ENST00000395962	ENST00000537334	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-5UTR	ENST00000395962	ENST00000537334	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5CDS-5UTR	ENST00000426905	ENST00000537334	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-5UTR	ENST00000426905	ENST00000537334	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5CDS-5UTR	ENST00000578071	ENST00000537334	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-5UTR	ENST00000578071	ENST00000537334	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5CDS-intron	ENST00000338034	ENST00000429152	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-intron	ENST00000338034	ENST00000429152	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5CDS-intron	ENST00000395962	ENST00000429152	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-intron	ENST00000395962	ENST00000429152	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5CDS-intron	ENST00000426905	ENST00000429152	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-intron	ENST00000426905	ENST00000429152	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5CDS-intron	ENST00000578071	ENST00000429152	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5CDS-intron	ENST00000578071	ENST00000429152	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5UTR-3CDS	ENST00000609345	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5UTR-3CDS	ENST00000609345	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5UTR-3CDS	ENST00000609345	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5UTR-3CDS	ENST00000609345	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5UTR-5UTR	ENST00000609345	ENST00000537334	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5UTR-5UTR	ENST00000609345	ENST00000537334	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
5UTR-intron	ENST00000609345	ENST00000429152	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
5UTR-intron	ENST00000609345	ENST00000429152	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
Frame-shift	ENST00000578071	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
Frame-shift	ENST00000578071	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
Frame-shift	ENST00000578071	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
Frame-shift	ENST00000578071	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
In-frame	ENST00000338034	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
In-frame	ENST00000338034	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
In-frame	ENST00000338034	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
In-frame	ENST00000338034	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
In-frame	ENST00000395962	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
In-frame	ENST00000395962	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
In-frame	ENST00000395962	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
In-frame	ENST00000395962	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
In-frame	ENST00000426905	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
In-frame	ENST00000426905	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+
In-frame	ENST00000426905	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+
In-frame	ENST00000426905	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000338034	ELAC2	chr17	12919085	-	ENST00000261643	COX10	chr17	14063194	+	2844	672	240	1379	379
ENST00000338034	ELAC2	chr17	12919085	-	ENST00000536205	COX10	chr17	14063194	+	1680	672	240	1379	379
ENST00000395962	ELAC2	chr17	12919085	-	ENST00000261643	COX10	chr17	14063194	+	2621	449	74	1156	360
ENST00000395962	ELAC2	chr17	12919085	-	ENST00000536205	COX10	chr17	14063194	+	1457	449	74	1156	360
ENST00000426905	ELAC2	chr17	12919085	-	ENST00000261643	COX10	chr17	14063194	+	2656	484	52	1191	379
ENST00000426905	ELAC2	chr17	12919085	-	ENST00000536205	COX10	chr17	14063194	+	1492	484	52	1191	379
ENST00000338034	ELAC2	chr17	12919084	-	ENST00000261643	COX10	chr17	14063193	+	2844	672	240	1379	379
ENST00000338034	ELAC2	chr17	12919084	-	ENST00000536205	COX10	chr17	14063193	+	1680	672	240	1379	379
ENST00000395962	ELAC2	chr17	12919084	-	ENST00000261643	COX10	chr17	14063193	+	2621	449	74	1156	360
ENST00000395962	ELAC2	chr17	12919084	-	ENST00000536205	COX10	chr17	14063193	+	1457	449	74	1156	360
ENST00000426905	ELAC2	chr17	12919084	-	ENST00000261643	COX10	chr17	14063193	+	2656	484	52	1191	379
ENST00000426905	ELAC2	chr17	12919084	-	ENST00000536205	COX10	chr17	14063193	+	1492	484	52	1191	379

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000338034	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+	0.07643659	0.92356336
ENST00000338034	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+	0.16374677	0.83625317
ENST00000395962	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+	0.09607704	0.90392303
ENST00000395962	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+	0.20640521	0.7935948
ENST00000426905	ENST00000261643	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+	0.07395462	0.92604536
ENST00000426905	ENST00000536205	ELAC2	chr17	12919085	-	COX10	chr17	14063194	+	0.17299695	0.82700306
ENST00000338034	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.07643659	0.92356336
ENST00000338034	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.16374677	0.83625317
ENST00000395962	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.09607704	0.90392303
ENST00000395962	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.20640521	0.7935948
ENST00000426905	ENST00000261643	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.07395462	0.92604536
ENST00000426905	ENST00000536205	ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.17299695	0.82700306

Top

Fusion Genomic Features for ELAC2-COX10

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.000131948	0.99986804
ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.000131948	0.99986804
ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.000131948	0.99986804
ELAC2	chr17	12919084	-	COX10	chr17	14063193	+	0.000131948	0.99986804

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ELAC2-COX10

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:12919085/chr17:14063194)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ELAC2 Q9BQ52	COX10 Q12887
FUNCTION: Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (PubMed:21593607). Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly (PubMed:24703694). {ECO:0000269\|PubMed:21593607, ECO:0000269\|PubMed:24703694}.	FUNCTION: Converts protoheme IX and farnesyl diphosphate to heme O. {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

COX10

chr17:12919084

chr17:14063193

ENST00000261643

235_255

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919084

chr17:14063193

ENST00000261643

257_277

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919084

chr17:14063193

ENST00000261643

280_300

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919084

chr17:14063193

ENST00000261643

309_329

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919084

chr17:14063193

ENST00000261643

364_384

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919084

chr17:14063193

ENST00000261643

411_431

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919085

chr17:14063194

ENST00000261643

235_255

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919085

chr17:14063194

ENST00000261643

257_277

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919085

chr17:14063194

ENST00000261643

280_300

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919085

chr17:14063194

ENST00000261643

309_329

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919085

chr17:14063194

ENST00000261643

364_384

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919085

chr17:14063194

ENST00000261643

411_431

208

444.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

COX10

chr17:12919084

chr17:14063193

ENST00000261643

174_194

208

444.0

Transmembrane

Helical

Tgene

COX10

chr17:12919085

chr17:14063194

ENST00000261643

174_194

208

444.0

Transmembrane

Helical

Top

Fusion Gene Sequence for ELAC2-COX10

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>26124_26124_1_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000338034_COX10_chr17_14063193_ENST00000261643_length(transcript)=2844nt_BP=672nt
AGAACTAGGGGCGGGGCCGCTTGAGACGCTCTAGTATTCCTCTACTCTATGGCCACTGTCAATTGACAAGTCCCGAGCGGTAAAGCTCCT
TTCTATTGGATGAGCAGCCTCGCGTAGGCGGGAAGCTCGGTGCACGGCGCGCTGATTGGCTGGATCCGCCATGCGGAGCGGCTAGGTGGT
GCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCC
GCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTG
CGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCG
GGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTA
AAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAA
ACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGA
CCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGG
GTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAAC
ACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTG
GGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATG
ATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTG
GACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGAC
CGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGA
GGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAAT
TCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTT
TTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTC
TTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTTCCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCA
TCCTTACCACCACACCACACGCACACTCCACATGCCCAGCAGAGTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTG
TAGTTCTGTGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCCCTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCC
CACACATTCTCAACCATAGTCCTTCTAACAATACCAATAGCTAGGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCT
TGGGAGTCTCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCACCCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATC
TTTATAGTTCACGTTAACATATAGACACTGTTGGAAGCAGTTCCTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGG
CCCCCACCCCATTACTGTACCTCTGGAGTCACTACTGTGGGTCGCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGA
AGGGAAGTTAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACAGAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGA
TATCTCCTGAATTCAGAAATTAGCCTCCACATGTGCAATGGCTTTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTG
GCCAGGTGTGGTCTCGGTTACCAAATACGGTTACCTGCAGCTTTTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAA
AGGTCTTGAAGCTTGACAGGATGTTTTCATTACTCAGTCTCCCAGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTT
AAACAACATTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGATTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCT
TCCCTCTTGGCTGCCCCCAGGTATTTACTGTGGAGAACATTGCATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACA

>26124_26124_1_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000338034_COX10_chr17_14063193_ENST00000261643_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------
>26124_26124_2_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000338034_COX10_chr17_14063193_ENST00000536205_length(transcript)=1680nt_BP=672nt
AGAACTAGGGGCGGGGCCGCTTGAGACGCTCTAGTATTCCTCTACTCTATGGCCACTGTCAATTGACAAGTCCCGAGCGGTAAAGCTCCT
TTCTATTGGATGAGCAGCCTCGCGTAGGCGGGAAGCTCGGTGCACGGCGCGCTGATTGGCTGGATCCGCCATGCGGAGCGGCTAGGTGGT
GCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCC
GCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTG
CGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCG
GGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTA
AAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAA
ACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGA
CCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGG
GTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAAC
ACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTG
GGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATG
ATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTG
GACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGAC
CGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGA
GGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAAT
TCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTT
TTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTC

>26124_26124_2_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000338034_COX10_chr17_14063193_ENST00000536205_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------
>26124_26124_3_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000395962_COX10_chr17_14063193_ENST00000261643_length(transcript)=2621nt_BP=449nt
AGCGGCTAGGTGGTGCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCT
CGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACC
CGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGG
GTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACT
GGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGT
TTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCT
TTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCC
TGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGG
GCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCC
TGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGC
GCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCA
ATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACC
TGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACG
CCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATT
ATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAG
CTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTT
CCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCATCCTTACCACCACACCACACGCACACTCCACATGCCCAGCAGA
GTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTGTAGTTCTGTGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCC
CTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCCCACACATTCTCAACCATAGTCCTTCTAACAATACCAATAGCTA
GGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCTTGGGAGTCTCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCAC
CCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATCTTTATAGTTCACGTTAACATATAGACACTGTTGGAAGCAGTTC
CTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGGCCCCCACCCCATTACTGTACCTCTGGAGTCACTACTGTGGGTC
GCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGAAGGGAAGTTAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACA
GAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGATATCTCCTGAATTCAGAAATTAGCCTCCACATGTGCAATGGCT
TTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTGGCCAGGTGTGGTCTCGGTTACCAAATACGGTTACCTGCAGCTT
TTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAAAGGTCTTGAAGCTTGACAGGATGTTTTCATTACTCAGTCTCCC
AGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTTAAACAACATTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGA
TTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCTTCCCTCTTGGCTGCCCCCAGGTATTTACTGTGGAGAACATTGC
ATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACATTTGTACAATTCATTGATTCTCTTTTCCTTCCACAATAAAATG

>26124_26124_3_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000395962_COX10_chr17_14063193_ENST00000261643_length(amino acids)=360AA_BP=125
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGVQRLMQEHKLKVARLDNIF
LTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALG
LFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLC
RRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPPPS

--------------------------------------------------------------
>26124_26124_4_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000395962_COX10_chr17_14063193_ENST00000536205_length(transcript)=1457nt_BP=449nt
AGCGGCTAGGTGGTGCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCT
CGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACC
CGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGG
GTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACT
GGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGT
TTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCT
TTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCC
TGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGG
GCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCC
TGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGC
GCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCA
ATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACC
TGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACG
CCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATT
ATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAG
CTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTT

>26124_26124_4_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000395962_COX10_chr17_14063193_ENST00000536205_length(amino acids)=360AA_BP=125
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGVQRLMQEHKLKVARLDNIF
LTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALG
LFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLC
RRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPPPS

--------------------------------------------------------------
>26124_26124_5_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000426905_COX10_chr17_14063193_ENST00000261643_length(transcript)=2656nt_BP=484nt
AACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGG
ACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCG
AGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGC
GCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGC
TCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCT
TCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT
TCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCC
ACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGT
CGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAAT
CCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGT
CACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCAC
CACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAG
CTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGA
CGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAAC
ACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATAT
TACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACA
TCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTTCCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCATCCTTACC
ACCACACCACACGCACACTCCACATGCCCAGCAGAGTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTGTAGTTCTG
TGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCCCTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCCCACACATT
CTCAACCATAGTCCTTCTAACAATACCAATAGCTAGGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCTTGGGAGTC
TCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCACCCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATCTTTATAGT
TCACGTTAACATATAGACACTGTTGGAAGCAGTTCCTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGGCCCCCACC
CCATTACTGTACCTCTGGAGTCACTACTGTGGGTCGCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGAAGGGAAGT
TAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACAGAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGATATCTCCT
GAATTCAGAAATTAGCCTCCACATGTGCAATGGCTTTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTGGCCAGGTG
TGGTCTCGGTTACCAAATACGGTTACCTGCAGCTTTTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAAAGGTCTTG
AAGCTTGACAGGATGTTTTCATTACTCAGTCTCCCAGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTTAAACAACA
TTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGATTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCTTCCCTCTT
GGCTGCCCCCAGGTATTTACTGTGGAGAACATTGCATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACATTTGTACA

>26124_26124_5_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000426905_COX10_chr17_14063193_ENST00000261643_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------
>26124_26124_6_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000426905_COX10_chr17_14063193_ENST00000536205_length(transcript)=1492nt_BP=484nt
AACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGG
ACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCG
AGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGC
GCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGC
TCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCT
TCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT
TCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCC
ACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGT
CGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAAT
CCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGT
CACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCAC
CACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAG
CTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGA
CGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAAC
ACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATAT
TACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACA

>26124_26124_6_ELAC2-COX10_ELAC2_chr17_12919084_ENST00000426905_COX10_chr17_14063193_ENST00000536205_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------
>26124_26124_7_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000338034_COX10_chr17_14063194_ENST00000261643_length(transcript)=2844nt_BP=672nt
AGAACTAGGGGCGGGGCCGCTTGAGACGCTCTAGTATTCCTCTACTCTATGGCCACTGTCAATTGACAAGTCCCGAGCGGTAAAGCTCCT
TTCTATTGGATGAGCAGCCTCGCGTAGGCGGGAAGCTCGGTGCACGGCGCGCTGATTGGCTGGATCCGCCATGCGGAGCGGCTAGGTGGT
GCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCC
GCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTG
CGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCG
GGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTA
AAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAA
ACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGA
CCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGG
GTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAAC
ACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTG
GGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATG
ATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTG
GACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGAC
CGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGA
GGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAAT
TCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTT
TTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTC
TTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTTCCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCA
TCCTTACCACCACACCACACGCACACTCCACATGCCCAGCAGAGTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTG
TAGTTCTGTGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCCCTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCC
CACACATTCTCAACCATAGTCCTTCTAACAATACCAATAGCTAGGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCT
TGGGAGTCTCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCACCCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATC
TTTATAGTTCACGTTAACATATAGACACTGTTGGAAGCAGTTCCTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGG
CCCCCACCCCATTACTGTACCTCTGGAGTCACTACTGTGGGTCGCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGA
AGGGAAGTTAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACAGAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGA
TATCTCCTGAATTCAGAAATTAGCCTCCACATGTGCAATGGCTTTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTG
GCCAGGTGTGGTCTCGGTTACCAAATACGGTTACCTGCAGCTTTTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAA
AGGTCTTGAAGCTTGACAGGATGTTTTCATTACTCAGTCTCCCAGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTT
AAACAACATTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGATTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCT
TCCCTCTTGGCTGCCCCCAGGTATTTACTGTGGAGAACATTGCATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACA

>26124_26124_7_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000338034_COX10_chr17_14063194_ENST00000261643_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------
>26124_26124_8_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000338034_COX10_chr17_14063194_ENST00000536205_length(transcript)=1680nt_BP=672nt
AGAACTAGGGGCGGGGCCGCTTGAGACGCTCTAGTATTCCTCTACTCTATGGCCACTGTCAATTGACAAGTCCCGAGCGGTAAAGCTCCT
TTCTATTGGATGAGCAGCCTCGCGTAGGCGGGAAGCTCGGTGCACGGCGCGCTGATTGGCTGGATCCGCCATGCGGAGCGGCTAGGTGGT
GCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCC
GCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTG
CGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCG
GGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTA
AAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAA
ACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGA
CCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGG
GTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAAC
ACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTG
GGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATG
ATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTG
GACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGAC
CGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGA
GGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAAT
TCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTT
TTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTC

>26124_26124_8_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000338034_COX10_chr17_14063194_ENST00000536205_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------
>26124_26124_9_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000395962_COX10_chr17_14063194_ENST00000261643_length(transcript)=2621nt_BP=449nt
AGCGGCTAGGTGGTGCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCT
CGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACC
CGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGG
GTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACT
GGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGT
TTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCT
TTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCC
TGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGG
GCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCC
TGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGC
GCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCA
ATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACC
TGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACG
CCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATT
ATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAG
CTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTT
CCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCATCCTTACCACCACACCACACGCACACTCCACATGCCCAGCAGA
GTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTGTAGTTCTGTGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCC
CTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCCCACACATTCTCAACCATAGTCCTTCTAACAATACCAATAGCTA
GGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCTTGGGAGTCTCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCAC
CCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATCTTTATAGTTCACGTTAACATATAGACACTGTTGGAAGCAGTTC
CTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGGCCCCCACCCCATTACTGTACCTCTGGAGTCACTACTGTGGGTC
GCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGAAGGGAAGTTAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACA
GAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGATATCTCCTGAATTCAGAAATTAGCCTCCACATGTGCAATGGCT
TTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTGGCCAGGTGTGGTCTCGGTTACCAAATACGGTTACCTGCAGCTT
TTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAAAGGTCTTGAAGCTTGACAGGATGTTTTCATTACTCAGTCTCCC
AGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTTAAACAACATTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGA
TTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCTTCCCTCTTGGCTGCCCCCAGGTATTTACTGTGGAGAACATTGC
ATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACATTTGTACAATTCATTGATTCTCTTTTCCTTCCACAATAAAATG

>26124_26124_9_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000395962_COX10_chr17_14063194_ENST00000261643_length(amino acids)=360AA_BP=125
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGVQRLMQEHKLKVARLDNIF
LTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALG
LFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLC
RRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPPPS

--------------------------------------------------------------
>26124_26124_10_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000395962_COX10_chr17_14063194_ENST00000536205_length(transcript)=1457nt_BP=449nt
AGCGGCTAGGTGGTGCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCT
CGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACC
CGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGG
GTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACT
GGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGT
TTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCT
TTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCC
TGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGG
GCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCC
TGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGC
GCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCA
ATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACC
TGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACG
CCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATT
ATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAG
CTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTT

>26124_26124_10_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000395962_COX10_chr17_14063194_ENST00000536205_length(amino acids)=360AA_BP=125
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGVQRLMQEHKLKVARLDNIF
LTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALG
LFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLC
RRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPPPS

--------------------------------------------------------------
>26124_26124_11_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000426905_COX10_chr17_14063194_ENST00000261643_length(transcript)=2656nt_BP=484nt
AACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGG
ACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCG
AGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGC
GCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGC
TCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCT
TCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT
TCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCC
ACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGT
CGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAAT
CCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGT
CACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCAC
CACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAG
CTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGA
CGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAAC
ACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATAT
TACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACA
TCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTTCCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCATCCTTACC
ACCACACCACACGCACACTCCACATGCCCAGCAGAGTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTGTAGTTCTG
TGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCCCTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCCCACACATT
CTCAACCATAGTCCTTCTAACAATACCAATAGCTAGGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCTTGGGAGTC
TCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCACCCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATCTTTATAGT
TCACGTTAACATATAGACACTGTTGGAAGCAGTTCCTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGGCCCCCACC
CCATTACTGTACCTCTGGAGTCACTACTGTGGGTCGCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGAAGGGAAGT
TAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACAGAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGATATCTCCT
GAATTCAGAAATTAGCCTCCACATGTGCAATGGCTTTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTGGCCAGGTG
TGGTCTCGGTTACCAAATACGGTTACCTGCAGCTTTTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAAAGGTCTTG
AAGCTTGACAGGATGTTTTCATTACTCAGTCTCCCAGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTTAAACAACA
TTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGATTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCTTCCCTCTT
GGCTGCCCCCAGGTATTTACTGTGGAGAACATTGCATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACATTTGTACA

>26124_26124_11_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000426905_COX10_chr17_14063194_ENST00000261643_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------
>26124_26124_12_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000426905_COX10_chr17_14063194_ENST00000536205_length(transcript)=1492nt_BP=484nt
AACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGG
ACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCG
AGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGC
GCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGC
TCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCT
TCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT
TCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCC
ACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGT
CGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAAT
CCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGT
CACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCAC
CACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAG
CTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGA
CGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAAC
ACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATAT
TACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACA

>26124_26124_12_ELAC2-COX10_ELAC2_chr17_12919085_ENST00000426905_COX10_chr17_14063194_ENST00000536205_length(amino acids)=379AA_BP=144
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG
VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA
VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR
EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ELAC2-COX10

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ELAC2-COX10

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ELAC2-COX10

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source