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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ELAVL1-BSG (FusionGDB2 ID:26135)

Fusion Gene Summary for ELAVL1-BSG

check button Fusion gene summary
Fusion gene informationFusion gene name: ELAVL1-BSG
Fusion gene ID: 26135
HgeneTgene
Gene symbol

ELAVL1

BSG

Gene ID

1994

682

Gene nameELAV like RNA binding protein 1basigin (Ok blood group)
SynonymsELAV1|HUR|Hua|MelG5F7|CD147|EMMPRIN|EMPRIN|OK|SLC7A11|TCSF
Cytomap

19p13.2

19p13.3

Type of geneprotein-codingprotein-coding
DescriptionELAV-like protein 1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)Hu antigen Rembryonic lethal, abnormal vision, drosophila, homolog-like 1hu-antigen RbasiginOK blood group antigencollagenase stimulatory factorextracellular matrix metalloproteinase inducerleukocyte activation antigen M6tumor cell-derived collagenase stimulatory factor
Modification date2020031320200315
UniProtAcc

Q15717

P35613

Ensembl transtripts involved in fusion geneENST00000351593, ENST00000407627, 
ENST00000593807, ENST00000596459, 
ENST00000333511, ENST00000353555, 
ENST00000545507, ENST00000574970, 
ENST00000346916, 
Fusion gene scores* DoF score4 X 4 X 4=649 X 12 X 6=648
# samples 414
** MAII scorelog2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/648*10)=-2.21056698593966
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ELAVL1 [Title/Abstract] AND BSG [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointELAVL1(8045966)-BSG(580378), # samples:1
Anticipated loss of major functional domain due to fusion event.ELAVL1-BSG seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ELAVL1-BSG seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ELAVL1-BSG seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ELAVL1-BSG seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneELAVL1

GO:0045727

positive regulation of translation

21613615

HgeneELAVL1

GO:0048255

mRNA stabilization

21613615|31358969

HgeneELAVL1

GO:0051260

protein homooligomerization

26595526

HgeneELAVL1

GO:0070935

3'-UTR-mediated mRNA stabilization

14517288|26489465|29180010


check buttonFusion gene breakpoints across ELAVL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BSG (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A8NVELAVL1chr19

8045966

-BSGchr19

580378

+


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Fusion Gene ORF analysis for ELAVL1-BSG

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000351593ENST00000333511ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000351593ENST00000353555ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000351593ENST00000545507ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000407627ENST00000333511ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000407627ENST00000353555ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000407627ENST00000545507ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000593807ENST00000333511ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000593807ENST00000353555ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000593807ENST00000545507ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000596459ENST00000333511ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000596459ENST00000353555ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-5UTRENST00000596459ENST00000545507ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-intronENST00000351593ENST00000574970ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-intronENST00000407627ENST00000574970ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-intronENST00000593807ENST00000574970ELAVL1chr19

8045966

-BSGchr19

580378

+
5CDS-intronENST00000596459ENST00000574970ELAVL1chr19

8045966

-BSGchr19

580378

+
Frame-shiftENST00000351593ENST00000346916ELAVL1chr19

8045966

-BSGchr19

580378

+
Frame-shiftENST00000593807ENST00000346916ELAVL1chr19

8045966

-BSGchr19

580378

+
Frame-shiftENST00000596459ENST00000346916ELAVL1chr19

8045966

-BSGchr19

580378

+
In-frameENST00000407627ENST00000346916ELAVL1chr19

8045966

-BSGchr19

580378

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000407627ELAVL1chr198045966-ENST00000346916BSGchr19580378+1741406461991176

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000407627ENST00000346916ELAVL1chr198045966-BSGchr19580378+0.0027971070.9972029

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Fusion Genomic Features for ELAVL1-BSG


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ELAVL1chr198045966-BSGchr19580378+9.88E-050.9999012
ELAVL1chr198045966-BSGchr19580378+9.88E-050.9999012

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ELAVL1-BSG


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:8045966/chr19:580378)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ELAVL1

Q15717

BSG

P35613

FUNCTION: RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability (PubMed:14517288, PubMed:18285462, PubMed:31358969). Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs (PubMed:8626503, PubMed:17632515, PubMed:18285462, PubMed:23519412, PubMed:14731398). Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro (PubMed:8626503). With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA (By similarity). Increases the stability of the leptin mRNA harboring an AU-rich element (ARE) in its 3' UTR (PubMed:29180010). {ECO:0000250|UniProtKB:P70372, ECO:0000269|PubMed:14517288, ECO:0000269|PubMed:14731398, ECO:0000269|PubMed:17632515, ECO:0000269|PubMed:18285462, ECO:0000269|PubMed:19029303, ECO:0000269|PubMed:23519412, ECO:0000269|PubMed:29180010, ECO:0000269|PubMed:31358969, ECO:0000269|PubMed:8626503}.FUNCTION: [Isoform 1]: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857). {ECO:0000250|UniProtKB:P18572, ECO:0000269|PubMed:21620857, ECO:0000269|PubMed:25957687}.; FUNCTION: [Isoform 2]: Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells (PubMed:11943775, PubMed:11688976). Plays an important role in targeting monocarboxylate transporters SLC16A1/GLUT1, SLC16A11 and SLC16A12 to the plasma membrane (PubMed:17127621, PubMed:21778275, PubMed:28666119). Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling (PubMed:25825981). Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA (isoform VEGF-165 and VEGF-121) and KDR/VEGFR2 in endothelial cells (PubMed:19837976). Plays a key role in regulating tumor growth, invasion, metastasis and neoangiogenesis by stimulating the production and release of extracellular matrix metalloproteinases and KDR/VEGFR2 by both tumor cells and stromal cells (fibroblasts and endothelial cells) (PubMed:12553375, PubMed:11992541, PubMed:15833850). {ECO:0000269|PubMed:11688976, ECO:0000269|PubMed:11943775, ECO:0000269|PubMed:11992541, ECO:0000269|PubMed:12553375, ECO:0000269|PubMed:15833850, ECO:0000269|PubMed:17127621, ECO:0000269|PubMed:19837976, ECO:0000269|PubMed:21778275, ECO:0000269|PubMed:25825981, ECO:0000269|PubMed:28666119}.; FUNCTION: [Isoform 1]: (Microbial infection) Erythrocyte receptor for P.falciparum RH5 which is essential for erythrocyte invasion by the merozoite stage of P.falciparum isolates 3D7 and Dd2. {ECO:0000269|PubMed:22080952}.; FUNCTION: [Isoform 2]: (Microbial infection) Erythrocyte receptor for P.falciparum RH5 which is essential for erythrocyte invasion by the merozoite stage of P.falciparum isolates 3D7, Dd2, 7G8 and HB3 (PubMed:22080952, PubMed:26195724). Binding of P.falciparum RH5 results in BSG dimerization which triggers an increase in intracellular Ca(2+) in the erythrocyte (PubMed:28409866). This essential step leads to a rearrangement of the erythrocyte cytoskeleton required for the merozoite invasion (PubMed:28409866). {ECO:0000269|PubMed:22080952, ECO:0000269|PubMed:26195724, ECO:0000269|PubMed:28409866}.; FUNCTION: [Isoform 2]: (Microbial infection) Can facilitate human SARS coronavirus (SARS-CoV-1) infection via its interaction with virus-associated PPIA/CYPA. {ECO:0000269|PubMed:15688292}.; FUNCTION: [Isoform 2]: (Microbial infection) Can facilitate HIV-1 infection via its interaction with virus-associated PPIA/CYPA. {ECO:0000269|PubMed:11353871}.; FUNCTION: [Isoform 2]: (Microbial infection) First described as a receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is not required for SARS-CoV-2 infection. {ECO:0000269|PubMed:33432067, ECO:0000303|PubMed:32307653}.; FUNCTION: [Isoform 2]: (Microbial infection) Acts as a receptor for measles virus. {ECO:0000269|PubMed:20147391}.; FUNCTION: [Isoform 2]: (Microbial infection) Promotes entry of pentamer-expressing human cytomegalovirus (HCMV) into epithelial and endothelial cells. {ECO:0000269|PubMed:29739904}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneBSGchr19:8045966chr19:580378ENST0000033351129356_359190587.3333333333334Compositional biasNote=Poly-Asp
TgeneBSGchr19:8045966chr19:580378ENST0000034691607356_35910359.6666666666667Compositional biasNote=Poly-Asp
TgeneBSGchr19:8045966chr19:580378ENST0000035355518356_35974476.6666666666667Compositional biasNote=Poly-Asp
TgeneBSGchr19:8045966chr19:580378ENST0000054550718356_3590333.3333333333333Compositional biasNote=Poly-Asp
TgeneBSGchr19:8045966chr19:580378ENST0000033351129221_315190587.3333333333334DomainIg-like V-type
TgeneBSGchr19:8045966chr19:580378ENST0000034691607138_21910359.6666666666667DomainIg-like C2-type
TgeneBSGchr19:8045966chr19:580378ENST0000034691607221_31510359.6666666666667DomainIg-like V-type
TgeneBSGchr19:8045966chr19:580378ENST000003469160737_12010359.6666666666667DomainIg-like
TgeneBSGchr19:8045966chr19:580378ENST0000035355518138_21974476.6666666666667DomainIg-like C2-type
TgeneBSGchr19:8045966chr19:580378ENST0000035355518221_31574476.6666666666667DomainIg-like V-type
TgeneBSGchr19:8045966chr19:580378ENST0000054550718138_2190333.3333333333333DomainIg-like C2-type
TgeneBSGchr19:8045966chr19:580378ENST0000054550718221_3150333.3333333333333DomainIg-like V-type
TgeneBSGchr19:8045966chr19:580378ENST000005455071837_1200333.3333333333333DomainIg-like
TgeneBSGchr19:8045966chr19:580378ENST0000033351129345_385190587.3333333333334Topological domainCytoplasmic
TgeneBSGchr19:8045966chr19:580378ENST0000034691607138_32310359.6666666666667Topological domainExtracellular
TgeneBSGchr19:8045966chr19:580378ENST0000034691607345_38510359.6666666666667Topological domainCytoplasmic
TgeneBSGchr19:8045966chr19:580378ENST0000035355518138_32374476.6666666666667Topological domainExtracellular
TgeneBSGchr19:8045966chr19:580378ENST0000035355518345_38574476.6666666666667Topological domainCytoplasmic
TgeneBSGchr19:8045966chr19:580378ENST0000054550718138_3230333.3333333333333Topological domainExtracellular
TgeneBSGchr19:8045966chr19:580378ENST0000054550718345_3850333.3333333333333Topological domainCytoplasmic
TgeneBSGchr19:8045966chr19:580378ENST0000033351129324_344190587.3333333333334TransmembraneHelical
TgeneBSGchr19:8045966chr19:580378ENST0000034691607324_34410359.6666666666667TransmembraneHelical
TgeneBSGchr19:8045966chr19:580378ENST0000035355518324_34474476.6666666666667TransmembraneHelical
TgeneBSGchr19:8045966chr19:580378ENST0000054550718324_3440333.3333333333333TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneELAVL1chr19:8045966chr19:580378ENST00000407627-36106_18692327.0DomainRRM 2
HgeneELAVL1chr19:8045966chr19:580378ENST00000407627-3620_9892327.0DomainRRM 1
HgeneELAVL1chr19:8045966chr19:580378ENST00000407627-36244_32292327.0DomainRRM 3
HgeneELAVL1chr19:8045966chr19:580378ENST00000596459-36106_18692327.0DomainRRM 2
HgeneELAVL1chr19:8045966chr19:580378ENST00000596459-3620_9892327.0DomainRRM 1
HgeneELAVL1chr19:8045966chr19:580378ENST00000596459-36244_32292327.0DomainRRM 3
TgeneBSGchr19:8045966chr19:580378ENST0000033351129138_219190587.3333333333334DomainIg-like C2-type
TgeneBSGchr19:8045966chr19:580378ENST000003335112937_120190587.3333333333334DomainIg-like
TgeneBSGchr19:8045966chr19:580378ENST000003535551837_12074476.6666666666667DomainIg-like
TgeneBSGchr19:8045966chr19:580378ENST0000033351129138_323190587.3333333333334Topological domainExtracellular


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Fusion Gene Sequence for ELAVL1-BSG


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26135_26135_1_ELAVL1-BSG_ELAVL1_chr19_8045966_ENST00000407627_BSG_chr19_580378_ENST00000346916_length(transcript)=1741nt_BP=406nt
CCGTCGCCGCCACCGCCGCCACCGCTACCGAGGCCGAGCGGAGCCGTTAGCGCCGCGCCGCCGCCGCCTCCCGCCCGCCCCGGAGCAGCC
CCGGGCCCGCCCGCCCGCATCCAGATTTTTGAAAAATACAATGTCTAATGGTTATGAAGACCACATGGCCGAAGACTGCAGGGGTGACAT
CGGGAGAACGAATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAGGATGAGTTACGAAGCCTGTTCAGCAGCATTGGTGAAGTTGA
ATCTGCAAAACTTATTCGGGATAAAGTAGCAGGACACAGCTTGGGCTATGGCTTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGC
GATCAACACGCTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGGTGGACTCCGACGACCAGTGGGGAGAGTACTCCTGCGTCTTCC
TCCCCGAGCCCATGGGCACGGCCAACATCCAGCTCCACGGGCCTCCCAGAGTGAAGGCTGTGAAGTCGTCAGAACACATCAACGAGGGGG
AGACGGCCATGCTGGTCTGCAAGTCAGAGTCCGTGCCACCTGTCACTGACTGGGCCTGGTACAAGATCACTGACTCTGAGGACAAGGCCC
TCATGAACGGCTCCGAGAGCAGGTTCTTCGTGAGTTCCTCGCAGGGCCGGTCAGAGCTACACATTGAGAACCTGAACATGGAGGCCGACC
CCGGCCAGTACCGGTGCAACGGCACCAGCTCCAAGGGCTCCGACCAGGCCATCATCACGCTCCGCGTGCGCAGCCACCTGGCCGCCCTCT
GGCCCTTCCTGGGCATCGTGGCTGAGGTGCTGGTGCTGGTCACCATCATCTTCATCTACGAGAAGCGCCGGAAGCCCGAGGACGTCCTGG
ATGATGACGACGCCGGCTCTGCACCCCTGAAGAGCAGCGGGCAGCACCAGAATGACAAAGGCAAGAACGTCCGCCAGAGGAACTCTTCCT
GAGGCAGGTGGCCCGAGGACGCTCCCTGCTCCACGTCTGCGCCGCCGCCGGAGTCCACTCCCAGTGCTTGCAAGATTCCAAGTTCTCACC
TCTTAAAGAAAACCCACCCCGTAGATTCCCATCATACACTTCCTTCTTTTTTAAAAAAGTTGGGTTTTCTCCATTCAGGATTCTGTTCCT
TAGGTTTTTTTCCTTCTGAAGTGTTTCACGAGAGCCCGGGAGCTGCTGCCCTGCGGCCCCGTCTGTGGCTTTCAGCCTCTGGGTCTGAGT
CATGGCCGGGTGGGCGGCACAGCCTTCTCCACTGGCCGGAGTCAGTGCCAGGTCCTTGCCCTTTGTGGAAAGTCACAGGTCACACGAGGG
GCCCCGTGTCCTGCCTGTCTGAAGCCAATGCTGTCTGGTTGCGCCATTTTTGTGCTTTTATGTTTAATTTTATGAGGGCCACGGGTCTGT
GTTCGACTCAGCCTCAGGGACGACTCTGACCTCTTGGCCACAGAGGACTCACTTGCCCACACCGAGGGCGACCCCGTCACAGCCTCAAGT
CACTCCCAAGCCCCCTCCTTGTCTGTGCATCCGGGGGCAGCTCTGGAGGGGGTTTGCTGGGGAACTGGCGCCATCGCCGGGACTCCAGAA
CCGCAGAAGCCTCCCCAGCTCACCCCTGGAGGACGGCCGGCTCTCTATAGCACCAGGGCTCACGTGGGAACCCCCCTCCCACCCACCGCC

>26135_26135_1_ELAVL1-BSG_ELAVL1_chr19_8045966_ENST00000407627_BSG_chr19_580378_ENST00000346916_length(amino acids)=176AA_BP=
MGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ELAVL1-BSG


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ELAVL1-BSG


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ELAVL1-BSG


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource