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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ELF3-GPR37L1 (FusionGDB2 ID:26177) |
Fusion Gene Summary for ELF3-GPR37L1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ELF3-GPR37L1 | Fusion gene ID: 26177 | Hgene | Tgene | Gene symbol | ELF3 | GPR37L1 | Gene ID | 1999 | 9283 |
| Gene name | E74 like ETS transcription factor 3 | G protein-coupled receptor 37 like 1 | |
| Synonyms | EPR-1|ERT|ESE-1|ESX | ET(B)R-LP-2|ETBR-LP-2|ETBRLP2 | |
| Cytomap | 1q32.1 | 1q32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ETS-related transcription factor Elf-3E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific)E74-like factor 3 (ets domain transcription factor)E74-like factor 3 (ets domain transcription factor, epithelial-specific )epith | G-protein coupled receptor 37-like 1endothelin B receptor-like protein 2endothelin type b receptor-like protein 2prosaposin receptor GPR37L1 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | P78545 | O60883 | |
| Ensembl transtripts involved in fusion gene | ENST00000495848, ENST00000359651, ENST00000367283, ENST00000367284, | ENST00000367282, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 12 X 6 X 7=504 |
| # samples | 3 | 16 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(16/504*10)=-1.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ELF3 [Title/Abstract] AND GPR37L1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ELF3(201980427)-GPR37L1(202096869), # samples:2 GPR37L1(202092721)-ELF3(201985008), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ELF3 | GO:0045892 | negative regulation of transcription, DNA-templated | 10773884 |
| Hgene | ELF3 | GO:0045893 | positive regulation of transcription, DNA-templated | 9234700 |
| Tgene | GPR37L1 | GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 23690594 |
| Tgene | GPR37L1 | GO:0043410 | positive regulation of MAPK cascade | 23690594 |
| Fusion gene breakpoints across ELF3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GPR37L1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STAD | TCGA-VQ-A8E7-01B | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + |
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Fusion Gene ORF analysis for ELF3-GPR37L1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000495848 | ENST00000367282 | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + |
| In-frame | ENST00000359651 | ENST00000367282 | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + |
| In-frame | ENST00000367283 | ENST00000367282 | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + |
| In-frame | ENST00000367284 | ENST00000367282 | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000359651 | ELF3 | chr1 | 201980427 | + | ENST00000367282 | GPR37L1 | chr1 | 202096869 | + | 9207 | 3355 | 3364 | 4170 | 268 |
| ENST00000367284 | ELF3 | chr1 | 201980427 | + | ENST00000367282 | GPR37L1 | chr1 | 202096869 | + | 6213 | 361 | 370 | 1176 | 268 |
| ENST00000367283 | ELF3 | chr1 | 201980427 | + | ENST00000367282 | GPR37L1 | chr1 | 202096869 | + | 6257 | 405 | 414 | 1220 | 268 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000359651 | ENST00000367282 | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + | 0.08225092 | 0.91774905 |
| ENST00000367284 | ENST00000367282 | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + | 0.08339192 | 0.91660804 |
| ENST00000367283 | ENST00000367282 | ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096869 | + | 0.08068882 | 0.91931117 |
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Fusion Genomic Features for ELF3-GPR37L1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096868 | + | 1.40E-05 | 0.99998593 |
| ELF3 | chr1 | 201980427 | + | GPR37L1 | chr1 | 202096868 | + | 1.40E-05 | 0.99998593 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ELF3-GPR37L1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:201980427/chr1:202096869) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ELF3 | GPR37L1 |
| FUNCTION: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity). {ECO:0000250, ECO:0000269|PubMed:10391676, ECO:0000269|PubMed:10644990, ECO:0000269|PubMed:10773884, ECO:0000269|PubMed:11036073, ECO:0000269|PubMed:11313868, ECO:0000269|PubMed:12414801, ECO:0000269|PubMed:12624109, ECO:0000269|PubMed:12682075, ECO:0000269|PubMed:12713734, ECO:0000269|PubMed:14715662, ECO:0000269|PubMed:14767472, ECO:0000269|PubMed:15075319, ECO:0000269|PubMed:15169914, ECO:0000269|PubMed:15794755, ECO:0000269|PubMed:16307850, ECO:0000269|PubMed:17060315, ECO:0000269|PubMed:9129154, ECO:0000269|PubMed:9234700, ECO:0000269|PubMed:9336459, ECO:0000269|PubMed:9395241, ECO:0000269|PubMed:9417054}. | FUNCTION: G-protein coupled receptor (PubMed:27072655). Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade (PubMed:23690594). However, other studies have shown that prosaposin does not increase activity (PubMed:27072655, PubMed:28688853). It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha (PubMed:27072655). Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway (By similarity). Regulates baseline blood pressure in females and protects against cardiovascular stress in males (By similarity). Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity (By similarity). {ECO:0000250|UniProtKB:Q99JG2, ECO:0000269|PubMed:23690594, ECO:0000269|PubMed:27072655, ECO:0000269|PubMed:28688853}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 418_439 | 210 | 482.0 | Compositional bias | Note=Cys-rich | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 227_251 | 210 | 482.0 | Topological domain | Cytoplasmic | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 273_310 | 210 | 482.0 | Topological domain | Extracellular | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 332_361 | 210 | 482.0 | Topological domain | Cytoplasmic | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 383_398 | 210 | 482.0 | Topological domain | Extracellular | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 420_481 | 210 | 482.0 | Topological domain | Cytoplasmic | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 252_272 | 210 | 482.0 | Transmembrane | Helical%3B Name%3D4 | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 311_331 | 210 | 482.0 | Transmembrane | Helical%3B Name%3D5 | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 362_382 | 210 | 482.0 | Transmembrane | Helical%3B Name%3D6 | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 399_419 | 210 | 482.0 | Transmembrane | Helical%3B Name%3D7 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000359651 | + | 1 | 8 | 273_355 | 54 | 372.0 | DNA binding | ETS |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000367283 | + | 2 | 9 | 273_355 | 54 | 372.0 | DNA binding | ETS |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000367284 | + | 2 | 9 | 273_355 | 54 | 372.0 | DNA binding | ETS |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000359651 | + | 1 | 8 | 46_132 | 54 | 372.0 | Domain | PNT |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000367283 | + | 2 | 9 | 46_132 | 54 | 372.0 | Domain | PNT |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000367284 | + | 2 | 9 | 46_132 | 54 | 372.0 | Domain | PNT |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000359651 | + | 1 | 8 | 137_145 | 54 | 372.0 | Motif | Note=9aaTAD |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000367283 | + | 2 | 9 | 137_145 | 54 | 372.0 | Motif | Note=9aaTAD |
| Hgene | ELF3 | chr1:201980427 | chr1:202096869 | ENST00000367284 | + | 2 | 9 | 137_145 | 54 | 372.0 | Motif | Note=9aaTAD |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 156_167 | 210 | 482.0 | Topological domain | Cytoplasmic | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 189_205 | 210 | 482.0 | Topological domain | Extracellular | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 26_134 | 210 | 482.0 | Topological domain | Extracellular | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 135_155 | 210 | 482.0 | Transmembrane | Helical%3B Name%3D1 | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 168_188 | 210 | 482.0 | Transmembrane | Helical%3B Name%3D2 | |
| Tgene | GPR37L1 | chr1:201980427 | chr1:202096869 | ENST00000367282 | 0 | 2 | 206_226 | 210 | 482.0 | Transmembrane | Helical%3B Name%3D3 |
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Fusion Gene Sequence for ELF3-GPR37L1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >26177_26177_1_ELF3-GPR37L1_ELF3_chr1_201980427_ENST00000359651_GPR37L1_chr1_202096869_ENST00000367282_length(transcript)=9207nt_BP=3355nt GTGCTGCCGTGTGGGCAAGCTCTGTGGGGAGAGGGGAGGCCAGTGGGTTGTTTTTGCCATCACAGAATACTGGGAAGCCCCTGGCATCCT GCTCCATAGCTCTCTTCACCACTATCCTGGAACCTTCTCCCCACCCCCATCCCCATGCCTCCAAGGCACTGACCTCAAATCCAAGTCTTT CTCACTTATCTCAAGCTGCCAGCCTGTAGGGATTCCTTATCTCAGCTCCATGTCAGCGGTGAGGAAGCCCCAAGAAGGCAAGGGAGCTGA CAGCCTTCTCATTTTTCTCGTACATCCTCCTGTTCACCCCGCCATCCCGGGAGCCCCAGCCAGATGCTCTTCAGGGCAGGGAGCACGTGA GCAGCCCTGGGGCTAGAAGCCGGTTCTCCCACATTCCTGGGTGAGGGACTGGGTGGAGGGTGTGCCTGCCTCAGGCTCCTTGGGGGAGGC CCCCTGAAGGGCTGGGGAAAATCCTACTGAGCCCCAGGCTCTCCTGCCTGCACTGGCCCAGTGCGGGGGCGGGGGGGCGGGGGGATCCTG GACATTAACTCTCTCCTAGGCACCTGGGAGCTTCAGAGAGGAAGAAGGTAAGGTAAGAAGCAGATTCTCTGCGCAGGACTTTCTTAGTCC TCAGGCTATAGAGTTAAAGAAAGAAGTATCTGTAGAAGGTGGAGTCACCTTTTGTTTGAGTAACCGTTTCACCCACCCTGGCTGAGGGTG GCCAGGAACTCCCCAAGTTGTGCATTAATGGAGGGGGGTCACACAGATCCTACATTTTTTTGTTTTTGTTTTTTTTTTTTTGAGACGCAG TGATTACAGGTGTGAGCCACCGGATCCTACATTTCAAATGCATAAAAATCTAGATATGGGCTGGGCGCAGTAGCTCATGCCTGTAATCCC AGCACTTTGGGAGGCTGAGGCAGGCAGATCATGAGGTCAGGAGATCGAGTCCATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAA ATACAGAAAGCCGGGCATGGCAGCGGGCGCCTGTAATCCCAGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGTCAGA GGTTGCAGTGAGCAGAGATCACGCCACTGCACTCCAACCTGGGCGACAGAGCGAGACTCCACCTCAAAACAAAATAAACAAAATACTAGA TCTGGAAGAGATCTTAGGGATTATTAAATTCAGACAACCTCATTTTTTATAGATGGGGAAACAAGCACAGACTCCAAGGGTCTCATCCAA GATCACACAGTTGCAGATGCTGGCTACAAGTCTCCTGCCTCAACCACCTGTATTACCCCATTCAGGGTCTCAAGAAGGGTCTATAAGACA CTATCCATTGTGTTTCGGGCTGAGTCCATAGAGACAACCACAGACATGGGGGACTCTGCCCACAGGGAAGGCAAGGGCTCTGGCCATGGA GCTGGATGGGAAGACTCTGAAGCCCGAAGACATTGAATCCTGTGCAGGGAAAGAGCGAGGGTTTTGTGTACAACACACCTGCATACCTGG ATGTGAATCTCAGCTCCACCCCTTCACCAACTCTGTGTGGCCTGGGCAAGCCATTCTAAGGGAACCCTCCACACTGCAACTTTCATGTCT ATAAAATGGGAATAACCATGCATTCCTTACAGGACTTTTTTGGTGTGAGGATTAAATGAGAGAATATGTTGAAAAGTGCTTGGTAAATAT ATTAATACTATGCATTCCCTCTTCTTTGAATGACGTGACCCAGGTAGTCAGGCTTCTGACCACTAGAGGGCAGCAGAAGGTACTGGAAAA CTGGGCCGAGTGAACCAGAGATTAGATGGGGTCCAGAGAGCAGGGATGAACTTACCCGTGTGGATTCTGGCAACTCCGGCAGGGAGGGCT CCAGCAGGCGCTGAGGGAAGAACTTTCAAGCAGAGCCGGGTCTCTTCAGGAGCGACTGCAGCAACCCTGATGCTTGGATGGAGTCCAGGC AGGTGATGGTAGTGAAGACCTTGCCAACAGAGTGGGCGCTGGAGAAGGAGCCCTTTAGTGGGGACCCTGGGGCCACGACTAGGCTGGCAG GCCCAGCCAGCACCAATTAATCCATGAGTATTGCCCAGCATTGAGCCTGGAGCACCTTCCAGCCCCTGGCCAGAGTCCTGGGTGTTCTGG GAAAAACCCCTAAACCTAGTAACTCCTCTCCCTACTAGGCCTCTTTGTTGCTGAATCTCTGGAATTTAGGGGCCAGCAGCTTTCTGACTC AGGTCAGCCAGGGGTTCATGTTCCCTCACTTGCCCTCCCCCTGCCTGGCCCATCTCTGGCCTGGCCCCTGGGAGGAATTTCCTGGGCCAG AGGGCAGCCGAAAGCACAGATGCCCACCCCAGCAACGTTCCCGCCACCTGCCCAGGCCAGTGCCCCGTGCCCAACCCCAGAGGGTGCGGG ATGACAGACTCTGACAATCATTAAACCAGCCGGGCCTGATTTCCCAGCACTGCCTGCTAAGATCCGGGCCAAGTGGCACTGAATATGCAA ATCACCTGGGGCCAGGAGCCCAGTCTAAAGGCCAGGAAATCCCCTCCATCCAATGAGACACCAGCTCAGGTTACTGCAGGGGACACACTA TAAAGCCCTGAGCTCAGGGAGGAGCTCCCTCCAGGCTCTATTTAGAGCCGGGTAGGGGAGCGCAGCGGCCAGATACCTCAGCGCTACCTG GCGGAACTGGATTTCTCTCCCGCCTGCCGGCCTGCCTGCCACAGCCGGACTCCGCCACTCCGGTAGGATTCCCCGCCTGTCATTCCCTAG CCCAGCTCTTGGGAAACTGCAGAGGGGTCCAGAGGATTTGCAGTTCTGAACCTGCACACTCCAGTCTAGGATCTCCGAGCAAGAGCGTAG GTGTCCTGAGGGTCAAAGAACAGAGAGAGATTGTCTCTGGGAAGGCAGAATGGCCATGACGCCGCTAGTCTGGCTCCAGGGCCCCAGAGA TCTGAGGAGGGAAGCCCAGCTGGAGGCTCCTGTGGTCCTGCCCTGGTCTGAGATCTTGGAGCCCTTCTTGAAGAGACGGTGTCCGCAGAG TTGCTGATCTTCCTGCCCCTGGGGGCTACTCTTGCCCAGGGTTGGGCAAAGCAGAGTAGCTGGGAGTGTAAGGAGAGGACCCTCGTCCCC TCACCAACCTCATCCTCTCTCCCCCTACCCACAGGTAGCCTCATGGCTGCAACCTGTGAGATTAGCAACATTTTTAGCAACTACTTCAGT GCGATGTACAGCTCGGAGGACTCCACCCTGGCCTCTGTTCCCCCTGCTGCCACCTTTGGGGCCGATGACTTGGTACTGACCCTGAGCAAC CCCCAGATGTCATTGGAGGGTACAGGTCTCCTCTCTGGGAGTCACGACTTTCAGCCTCTGTGCCCTGGGCATTGACCGCTTCCACGTGGC CACCAGCACCCTGCCCAAGGTGAGGCCCATCGAGCGGTGCCAATCCATCCTGGCCAAGTTGGCTGTCATCTGGGTGGGCTCCATGACGCT GGCTGTGCCTGAGCTCCTGCTGTGGCAGCTGGCACAGGAGCCTGCCCCCACCATGGGCACCCTGGACTCATGCATCATGAAACCCTCAGC CAGCCTGCCCGAGTCCCTGTATTCACTGGTGATGACCTACCAGAACGCCCGCATGTGGTGGTACTTTGGCTGCTACTTCTGCCTGCCCAT CCTCTTCACAGTCACCTGCCAGCTGGTGACATGGCGGGTGCGAGGCCCTCCAGGGAGGAAGTCAGAGTGCAGGGCCAGCAAGCACGAGCA GTGTGAGAGCCAGCTCAACAGCACCGTGGTGGGCCTGACCGTGGTCTACGCCTTCTGCACCCTCCCAGAGAACGTCTGCAACATCGTGGT GGCCTACCTCTCCACCGAGCTGACCCGCCAGACCCTGGACCTCCTGGGCCTCATCAACCAGTTCTCCACCTTCTTCAAGGGCGCCATCAC CCCAGTGCTGCTCCTTTGCATCTGCAGGCCGCTGGGCCAGGCCTTCCTGGACTGCTGCTGCTGCTGCTGCTGTGAGGAGTGCGGCGGGGC TTCGGAGGCCTCTGCTGCCAATGGGTCGGACAACAAGCTCAAGACCGAGGTGTCCTCTTCCATCTACTTCCACAAGCCCAGGGAGTCACC CCCACTCCTGCCCCTGGGCACACCTTGCTGAGGCCCCAGTAGGGGTGGGGAGGGAGGGAGAGGCCGCCACCCCCGCCGGTGTCTGCTGTT CTTTCCCCATAGGTCTTGCTTTGTTGCCTGTCTTGCTGTCTAGGGATGGACTTGGTTCCTCTTGTCAAGGTTTGGGAATGTCAAAGCCCC CTCCCCACACAGGGCCTTTCCTGTCCCTTGTGGGGCCTTCCAACCCTGTCCTTTCCACTGGTGGGCGGTGATGCTTCTAGGTCCTTAGAA CTGCCCAGAAACTCTGAGTCCCAGCAGCTGGGAGCCAGAACTTTGCCTGCCCTCCCTTGGTTCCAGTCTCTCTTCTCTCTCTCTGCCTTG GAACCTGACCATACTTTAGTTGTGCCCTTCCCAGGCATCATCCTCCTACCACCAACCTGGGGCCCCATCTTGGAATGGGGGCTCCTTGGG GCCAGCCCAGTGTGGCTCACCACACTCTTCTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTACAT TTGCCTGATGTCAGCTCCCTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGT GCACCAACACACCCGGCTAATTTTTGTATTTGTAGAAGAGGCGGGGTTTCACCATGTTGGCCAGGCTGGTGTTGAACTCCTGACCTCAAG TGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTGCCACGCCCAGCCCCAGTACACTCTTCTCTGGACCAGATC TGTCCCAGTCCTGGATGCCTCCTCCTACTGGTGCCTTCTTTTCTTCCAGAGGATTTCTCTCTCCTTCCTCCTCCTTTCTTTGGGATCCCT GGGTTGCCCTGTCCCAACCTCCTTGTTAGGTGCTTTCCCATAGGAGGCCCTTCTTGAGAAACAATAAACTAGGTAGAACTACCCCTATGC CCATCCACTTTCTTGTGCCACATTCTGGCAGGGCCCAGATGCAGCTGGGCCTTCCTGGCCTGGCAGTGCCTAGGAGAATTTCTCCTGACC TGGCCTGGCCTGTGGCTGATGTTCAGAACAGCCTTGTGGCCGATGTTCAGAACAGCCTTGTGGCCCTGGCGACTCCAAGGGTTTTATGGC TTTTGAGGGACAGAGAGGATGGAGGGCTTGGGGAGCCGGAGGACCTAAGTCCTCATCCTGGCCTAAACCCCATGCTCCTTGGGAAGTCAA AAGCCTGGAAAATATCTCCTCTGGAGCCTTCATCTCTGCTATGCCCTCTCTCCACAAAGCCCCCCTTGGAGGGAGTCCAGTGGTCTTTCC TCTGTGAGCCCCAGGGCTTCCCAGCCTTTGTCACTCTGAGAGCTGCTCTTGTTCAGTTTCTTAGAATGGACTGTTTTGCCTGTAGACGGC CCAGCTGCCTGCCCTGGCCTGCCCCCACCCAGCCCCCACTGCACCACCCTTCCCGCCAGAGCTCCCACTGCCCCCGGCAGACCCTTCATG CAGCTTCTCCTGTGGGGTCTTGCCCTTGAAGTGCCACTTCCCCCAGCCCCACCTCTGGTCCCTTCCAGAGGGCACCCTTAGCCTTGTAGG TCCCTGGGAAGCTGGCACAGCATCAACCAGAAGTGATGCCTCAGCCAGGCCACCAGTCGCTCCCCGCCTGGGAGCTCAGCTTTCCTCAGA ACCACCCCCCCTGTCTGAAGCTCTGTCCTGGGTCCCACCAGACTTCTGCCCACCAGGCCTACCTACAGCATCCACATGGGGCCTCAGGAA GGGCCCCGGGGGCCCAGGGATGGGCAGGGGCAGGGTTTCCAAGCGCCTGGGGCTCCATTCTCCTCTGTCCACCCACCCACACCCCTTGGC CTCAGCCTGCCCTGTACCCAAGCTTCCCTCCCCCTCTCCTGGGGATCTTAACGGCCTTGTTCTCTCTCCCTGGCACCCACCCCCAGGGCG GGTGATGCCGCCAAGAGAGAGGGAGGCCGTTGCTAGGTGATGGCGCCGCCATGCACACACCCTTTGTGCTGGGGAGTGACACCCACCCGT TTCTCAGCAGACCTGTTGCCACGGTGACTGAAGCCCCCAGCTCTGTCTGTAGAAACTTCAGATGGGTGGGGGAGCAGGTTGGAGAGGGGA CCAAAGGCAGGCCTGTCGTGCTGAAGCTCTTGGGGACCGTTTCCTCGGCATTTCCCCAACTCCTTCTCCACCCCCCTGCCAGGCCCGGAA GTACCACCAGCTTCCTAAGGGATGCAGGAAGGGGCCGGGTGAACTGAGGTGAAGTCCAGGGCAGGGGAGTCAGACCCCTCAACATCCTGT TTAGGGGTCCTCCTCCACAAAGGGTGCCCTCCACCTCTCCCTCCTGCTGGTTGGCCGGCTCAGAGATGAAGGGGGAGAGATGGTGGCTCC AAGGCTCTGCCACCGCCACCTCCCAAGCCTGCCAACGTGAATGGCTTGCAGAATCAGTCAGCAGGCCAGCGGCCTTGGGAAAGAGCCACT GTCCTCGCAGCCTGGGCCAGCTGGGGGAACAATGTAGGGTTTGTTGCTTAGGGGTCCCAGGCTTGCGGGGGGGTTGGCACATGGTGGGCA GTGGACTTGAGCTGGGATGGTCTGAGGGGGCACTGACACGCTCACCCGAGGGCAGACTTCAGACCAGCCCTCAGATCCTGATGCCAGGTT ACAGGGCTGAGGGGAGCCTGAAATCCACTGGGTCTCCCTGCTCCACTTGGGAGTCACCTTCTCATCACCTATCCTGGAACTGAATGCAAT TACTTAAACTCAGTCTCAGCTTCCTCATCTGTAAAATGGGAATAATCTGTCCTTCACAGAGGATTATGGTCATTTAATGAGACAAGATAC ATAAAGCACTTTGCATGGTGCCCCGAACCTTTTATTCCTTCCTCTCCTTTGGGAATTCAATTCTCTAGTGTTAGGAGCAGGCTTGGCCCA GGGATTCTTAAATGCATCCAGGTTTTGGCATCAAAGGGCCCCAAACATGACAATTTACCTATACTCATGGTCTGTTCCCATTCAACTTTA ATAGGTTATGTGTGTTTTTTTTTTCTTAAGAGCTGGGTGGGGGGGTCTCACTATGTTGCCCAGGCTGGCTTTGAACTCCTGGGCTCAAGC AGTCCTCCTGTCTCAGCCTCCTGAGTAGCTGGGACTACAAGTGTGTACCACCATGCCTGGCTGAACACTTTTTTTTTTTTGAGACAAGAT CCCACTCAGTCACTCAAGCTGAGTGCTGTGGTGTGATCACAGCTCATTGCAGCCTCCACTTCCTGGGCTCAAGCGATTCTCCTGCCTCAG CTTCCTGAGTAGCTGGGACTACAGGTGCGCACTACCACGCCTGTCTAATTTTTGATTATTTGTAGAGATAGGGTCTCACTATTTTGCCCA GGCTGGTCTCAAACTCCCAGACTCAAGTCATTCTCCTACCTCGGGCTCCCAAAGTACTGGGATTACAGGCATGAGCACCTGGCCCCTGAA CAAATTCTTTAAGTCATATTAGCACCTGCTGCACGCCGGCACTGTGGAAGGAGGATGCTTGCTTGCTTCCTGGTAACCAGCTCTCTTATC TCAAACCTCAATCCTCAGTGAGGATCACAGGATCTGAGAAAGGCACCTTGGCCTGGAAACAGCCCCAGATGAGTGAGATTGCTGGTCCTC TCCCGGGATCCCAGGCCCAGGAAAACCTAGCCATGCTTGCAGTCAGGAGAGGGCAGGGGATAGAGCCCTGGCTCCCATTCAACCTCCTTA GCCAGGAGGACATGTCCCATTTTGCTTAGGAGTTGGGAGGTACCCTAGAATCACTTAGCTTCAGATGCCAAATTCCATCCACATTCTTTC CTCCAACTCTCTGGCAGTGGGGAACTGCCTCTCCAGGCAGGGAACTGCTCTGACAGGTCTGATGACTGCCTCCAGGAGGAAGCCCTGGGC ACCAATGAAGGTGAGGGGCTGGAGGGCCCAGGACGGGGAGTCAAGGTCCCCACTCCCAGGACTAAGGGACAGTTTGGCTCCTTTTTCCTG CAGTGGGAGGGGTGAGAAGGGCTGGGGTGTTCTGCAAGGGCCTGCTCCATTTTCCAGGGTGAAGGAGAGGCCGAGGGAGGTGGAGCGGGA GGAGGTGGGGCTTACTGTGAAACTGGGTCAAGATGGCCTCGGATTTGAGCAGGCAGGGTCACCAGGCTCTGAGGCAGCAGCTGTGAGCAG TGCCGAGGGAGGACCAGCTCTGACGGTGAGGTCGGGTGGGGGACTAGAATCCAGCAGAGGAGCGAGGGCAGGGCTCCTACCAGGAAACCC ATAGCATTGACACTAACTGAGAGGCAGCAAAGGCGGTGACACTCCCCCAGGCTCTGTGGGCCCAGCCCTACCCCTGAAGCACAGTTAACT GGTTCTGGGGTAGGAACTGGGGGCCGGAGGGACAGGGTTCTGGTTCTGGCTCAACCTTGGCTGCTGGTGAGATCCAGGGCCTGGGAAAGA GGGGCTGAGGCCTGAACTGGGCCTAAGGAGAGTGCAGCTCAGTTCGCACACAACAGCACCCAGCCCTGTCCCCTTGCTGCCTCTACCCAG CCCTGGGCAGTTCCCTCAACAGAGCTCTGCAGCCCCAAGTGGCAGCTGCTGGCTCAAAGCTGGGACTACATGAAAGTCTGAAAAGAGAAT GAGAAGGAGGTGGCGCAAGAGCCTGGACGCACGTGTGGGAGGCCGTTTTGTGCAGCGCCATTGTGCTCCCCGGGCGGGCATGTGCTCGCG CTCCGTGGCTCTGTTGGTGCCCAGCGTGCGGGGGTGTGCTGGTGGCCCTGTGGGCCTGTAGGGCAACCCATGCCAACTGCGGAAAAGTAA CCAGCACCATACACCCCCCCCAACACAAAACTGGTCATTTATTTTTTTTGTTGTCATTGTTATTAGGAAGCAAAAAAATGTACAGTTACA AGAATCATTTTCCAAACAGAGGTTAAATATGAGCTGAAAAGTGTAAAAAAGGAAGAGGAACATCACTTTACAAATCATTAAATTAAACAA >26177_26177_1_ELF3-GPR37L1_ELF3_chr1_201980427_ENST00000359651_GPR37L1_chr1_202096869_ENST00000367282_length(amino acids)=268AA_BP= MGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVM TYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQT -------------------------------------------------------------- >26177_26177_2_ELF3-GPR37L1_ELF3_chr1_201980427_ENST00000367283_GPR37L1_chr1_202096869_ENST00000367282_length(transcript)=6257nt_BP=405nt AGGCTCTATTTAGAGCCGGGTAGGGGAGCGCAGCGGCCAGATACCTCAGCGCTACCTGGCGGAACTGGATTTCTCTCCCGCCTGCCGGCC TGCCTGCCACAGCCGGACTCCGCCACTCCGGTAGGATTCCCCGCCTGTCATTCCCTAGCCCAGCTCTTGGGAAACTGCAGAGGGGTCCAG AGGATTTGCAGTTCTGAACCTGCACACTCCAGTCTAGGATCTCCGAGCAAGAGCGTAGCCTCATGGCTGCAACCTGTGAGATTAGCAACA TTTTTAGCAACTACTTCAGTGCGATGTACAGCTCGGAGGACTCCACCCTGGCCTCTGTTCCCCCTGCTGCCACCTTTGGGGCCGATGACT TGGTACTGACCCTGAGCAACCCCCAGATGTCATTGGAGGGTACAGGTCTCCTCTCTGGGAGTCACGACTTTCAGCCTCTGTGCCCTGGGC ATTGACCGCTTCCACGTGGCCACCAGCACCCTGCCCAAGGTGAGGCCCATCGAGCGGTGCCAATCCATCCTGGCCAAGTTGGCTGTCATC TGGGTGGGCTCCATGACGCTGGCTGTGCCTGAGCTCCTGCTGTGGCAGCTGGCACAGGAGCCTGCCCCCACCATGGGCACCCTGGACTCA TGCATCATGAAACCCTCAGCCAGCCTGCCCGAGTCCCTGTATTCACTGGTGATGACCTACCAGAACGCCCGCATGTGGTGGTACTTTGGC TGCTACTTCTGCCTGCCCATCCTCTTCACAGTCACCTGCCAGCTGGTGACATGGCGGGTGCGAGGCCCTCCAGGGAGGAAGTCAGAGTGC AGGGCCAGCAAGCACGAGCAGTGTGAGAGCCAGCTCAACAGCACCGTGGTGGGCCTGACCGTGGTCTACGCCTTCTGCACCCTCCCAGAG AACGTCTGCAACATCGTGGTGGCCTACCTCTCCACCGAGCTGACCCGCCAGACCCTGGACCTCCTGGGCCTCATCAACCAGTTCTCCACC TTCTTCAAGGGCGCCATCACCCCAGTGCTGCTCCTTTGCATCTGCAGGCCGCTGGGCCAGGCCTTCCTGGACTGCTGCTGCTGCTGCTGC TGTGAGGAGTGCGGCGGGGCTTCGGAGGCCTCTGCTGCCAATGGGTCGGACAACAAGCTCAAGACCGAGGTGTCCTCTTCCATCTACTTC CACAAGCCCAGGGAGTCACCCCCACTCCTGCCCCTGGGCACACCTTGCTGAGGCCCCAGTAGGGGTGGGGAGGGAGGGAGAGGCCGCCAC CCCCGCCGGTGTCTGCTGTTCTTTCCCCATAGGTCTTGCTTTGTTGCCTGTCTTGCTGTCTAGGGATGGACTTGGTTCCTCTTGTCAAGG TTTGGGAATGTCAAAGCCCCCTCCCCACACAGGGCCTTTCCTGTCCCTTGTGGGGCCTTCCAACCCTGTCCTTTCCACTGGTGGGCGGTG ATGCTTCTAGGTCCTTAGAACTGCCCAGAAACTCTGAGTCCCAGCAGCTGGGAGCCAGAACTTTGCCTGCCCTCCCTTGGTTCCAGTCTC TCTTCTCTCTCTCTGCCTTGGAACCTGACCATACTTTAGTTGTGCCCTTCCCAGGCATCATCCTCCTACCACCAACCTGGGGCCCCATCT TGGAATGGGGGCTCCTTGGGGCCAGCCCAGTGTGGCTCACCACACTCTTCTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTG TTGCCCAGGCTGGAGTACATTTGCCTGATGTCAGCTCCCTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGA GTAGCTGGGATTACAGGTGTGCACCAACACACCCGGCTAATTTTTGTATTTGTAGAAGAGGCGGGGTTTCACCATGTTGGCCAGGCTGGT GTTGAACTCCTGACCTCAAGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTGCCACGCCCAGCCCCAGTAC ACTCTTCTCTGGACCAGATCTGTCCCAGTCCTGGATGCCTCCTCCTACTGGTGCCTTCTTTTCTTCCAGAGGATTTCTCTCTCCTTCCTC CTCCTTTCTTTGGGATCCCTGGGTTGCCCTGTCCCAACCTCCTTGTTAGGTGCTTTCCCATAGGAGGCCCTTCTTGAGAAACAATAAACT AGGTAGAACTACCCCTATGCCCATCCACTTTCTTGTGCCACATTCTGGCAGGGCCCAGATGCAGCTGGGCCTTCCTGGCCTGGCAGTGCC TAGGAGAATTTCTCCTGACCTGGCCTGGCCTGTGGCTGATGTTCAGAACAGCCTTGTGGCCGATGTTCAGAACAGCCTTGTGGCCCTGGC GACTCCAAGGGTTTTATGGCTTTTGAGGGACAGAGAGGATGGAGGGCTTGGGGAGCCGGAGGACCTAAGTCCTCATCCTGGCCTAAACCC CATGCTCCTTGGGAAGTCAAAAGCCTGGAAAATATCTCCTCTGGAGCCTTCATCTCTGCTATGCCCTCTCTCCACAAAGCCCCCCTTGGA GGGAGTCCAGTGGTCTTTCCTCTGTGAGCCCCAGGGCTTCCCAGCCTTTGTCACTCTGAGAGCTGCTCTTGTTCAGTTTCTTAGAATGGA CTGTTTTGCCTGTAGACGGCCCAGCTGCCTGCCCTGGCCTGCCCCCACCCAGCCCCCACTGCACCACCCTTCCCGCCAGAGCTCCCACTG CCCCCGGCAGACCCTTCATGCAGCTTCTCCTGTGGGGTCTTGCCCTTGAAGTGCCACTTCCCCCAGCCCCACCTCTGGTCCCTTCCAGAG GGCACCCTTAGCCTTGTAGGTCCCTGGGAAGCTGGCACAGCATCAACCAGAAGTGATGCCTCAGCCAGGCCACCAGTCGCTCCCCGCCTG GGAGCTCAGCTTTCCTCAGAACCACCCCCCCTGTCTGAAGCTCTGTCCTGGGTCCCACCAGACTTCTGCCCACCAGGCCTACCTACAGCA TCCACATGGGGCCTCAGGAAGGGCCCCGGGGGCCCAGGGATGGGCAGGGGCAGGGTTTCCAAGCGCCTGGGGCTCCATTCTCCTCTGTCC ACCCACCCACACCCCTTGGCCTCAGCCTGCCCTGTACCCAAGCTTCCCTCCCCCTCTCCTGGGGATCTTAACGGCCTTGTTCTCTCTCCC TGGCACCCACCCCCAGGGCGGGTGATGCCGCCAAGAGAGAGGGAGGCCGTTGCTAGGTGATGGCGCCGCCATGCACACACCCTTTGTGCT GGGGAGTGACACCCACCCGTTTCTCAGCAGACCTGTTGCCACGGTGACTGAAGCCCCCAGCTCTGTCTGTAGAAACTTCAGATGGGTGGG GGAGCAGGTTGGAGAGGGGACCAAAGGCAGGCCTGTCGTGCTGAAGCTCTTGGGGACCGTTTCCTCGGCATTTCCCCAACTCCTTCTCCA CCCCCCTGCCAGGCCCGGAAGTACCACCAGCTTCCTAAGGGATGCAGGAAGGGGCCGGGTGAACTGAGGTGAAGTCCAGGGCAGGGGAGT CAGACCCCTCAACATCCTGTTTAGGGGTCCTCCTCCACAAAGGGTGCCCTCCACCTCTCCCTCCTGCTGGTTGGCCGGCTCAGAGATGAA GGGGGAGAGATGGTGGCTCCAAGGCTCTGCCACCGCCACCTCCCAAGCCTGCCAACGTGAATGGCTTGCAGAATCAGTCAGCAGGCCAGC GGCCTTGGGAAAGAGCCACTGTCCTCGCAGCCTGGGCCAGCTGGGGGAACAATGTAGGGTTTGTTGCTTAGGGGTCCCAGGCTTGCGGGG GGGTTGGCACATGGTGGGCAGTGGACTTGAGCTGGGATGGTCTGAGGGGGCACTGACACGCTCACCCGAGGGCAGACTTCAGACCAGCCC TCAGATCCTGATGCCAGGTTACAGGGCTGAGGGGAGCCTGAAATCCACTGGGTCTCCCTGCTCCACTTGGGAGTCACCTTCTCATCACCT ATCCTGGAACTGAATGCAATTACTTAAACTCAGTCTCAGCTTCCTCATCTGTAAAATGGGAATAATCTGTCCTTCACAGAGGATTATGGT CATTTAATGAGACAAGATACATAAAGCACTTTGCATGGTGCCCCGAACCTTTTATTCCTTCCTCTCCTTTGGGAATTCAATTCTCTAGTG TTAGGAGCAGGCTTGGCCCAGGGATTCTTAAATGCATCCAGGTTTTGGCATCAAAGGGCCCCAAACATGACAATTTACCTATACTCATGG TCTGTTCCCATTCAACTTTAATAGGTTATGTGTGTTTTTTTTTTCTTAAGAGCTGGGTGGGGGGGTCTCACTATGTTGCCCAGGCTGGCT TTGAACTCCTGGGCTCAAGCAGTCCTCCTGTCTCAGCCTCCTGAGTAGCTGGGACTACAAGTGTGTACCACCATGCCTGGCTGAACACTT TTTTTTTTTTGAGACAAGATCCCACTCAGTCACTCAAGCTGAGTGCTGTGGTGTGATCACAGCTCATTGCAGCCTCCACTTCCTGGGCTC AAGCGATTCTCCTGCCTCAGCTTCCTGAGTAGCTGGGACTACAGGTGCGCACTACCACGCCTGTCTAATTTTTGATTATTTGTAGAGATA GGGTCTCACTATTTTGCCCAGGCTGGTCTCAAACTCCCAGACTCAAGTCATTCTCCTACCTCGGGCTCCCAAAGTACTGGGATTACAGGC ATGAGCACCTGGCCCCTGAACAAATTCTTTAAGTCATATTAGCACCTGCTGCACGCCGGCACTGTGGAAGGAGGATGCTTGCTTGCTTCC TGGTAACCAGCTCTCTTATCTCAAACCTCAATCCTCAGTGAGGATCACAGGATCTGAGAAAGGCACCTTGGCCTGGAAACAGCCCCAGAT GAGTGAGATTGCTGGTCCTCTCCCGGGATCCCAGGCCCAGGAAAACCTAGCCATGCTTGCAGTCAGGAGAGGGCAGGGGATAGAGCCCTG GCTCCCATTCAACCTCCTTAGCCAGGAGGACATGTCCCATTTTGCTTAGGAGTTGGGAGGTACCCTAGAATCACTTAGCTTCAGATGCCA AATTCCATCCACATTCTTTCCTCCAACTCTCTGGCAGTGGGGAACTGCCTCTCCAGGCAGGGAACTGCTCTGACAGGTCTGATGACTGCC TCCAGGAGGAAGCCCTGGGCACCAATGAAGGTGAGGGGCTGGAGGGCCCAGGACGGGGAGTCAAGGTCCCCACTCCCAGGACTAAGGGAC AGTTTGGCTCCTTTTTCCTGCAGTGGGAGGGGTGAGAAGGGCTGGGGTGTTCTGCAAGGGCCTGCTCCATTTTCCAGGGTGAAGGAGAGG CCGAGGGAGGTGGAGCGGGAGGAGGTGGGGCTTACTGTGAAACTGGGTCAAGATGGCCTCGGATTTGAGCAGGCAGGGTCACCAGGCTCT GAGGCAGCAGCTGTGAGCAGTGCCGAGGGAGGACCAGCTCTGACGGTGAGGTCGGGTGGGGGACTAGAATCCAGCAGAGGAGCGAGGGCA GGGCTCCTACCAGGAAACCCATAGCATTGACACTAACTGAGAGGCAGCAAAGGCGGTGACACTCCCCCAGGCTCTGTGGGCCCAGCCCTA CCCCTGAAGCACAGTTAACTGGTTCTGGGGTAGGAACTGGGGGCCGGAGGGACAGGGTTCTGGTTCTGGCTCAACCTTGGCTGCTGGTGA GATCCAGGGCCTGGGAAAGAGGGGCTGAGGCCTGAACTGGGCCTAAGGAGAGTGCAGCTCAGTTCGCACACAACAGCACCCAGCCCTGTC CCCTTGCTGCCTCTACCCAGCCCTGGGCAGTTCCCTCAACAGAGCTCTGCAGCCCCAAGTGGCAGCTGCTGGCTCAAAGCTGGGACTACA TGAAAGTCTGAAAAGAGAATGAGAAGGAGGTGGCGCAAGAGCCTGGACGCACGTGTGGGAGGCCGTTTTGTGCAGCGCCATTGTGCTCCC CGGGCGGGCATGTGCTCGCGCTCCGTGGCTCTGTTGGTGCCCAGCGTGCGGGGGTGTGCTGGTGGCCCTGTGGGCCTGTAGGGCAACCCA TGCCAACTGCGGAAAAGTAACCAGCACCATACACCCCCCCCAACACAAAACTGGTCATTTATTTTTTTTGTTGTCATTGTTATTAGGAAG CAAAAAAATGTACAGTTACAAGAATCATTTTCCAAACAGAGGTTAAATATGAGCTGAAAAGTGTAAAAAAGGAAGAGGAACATCACTTTA >26177_26177_2_ELF3-GPR37L1_ELF3_chr1_201980427_ENST00000367283_GPR37L1_chr1_202096869_ENST00000367282_length(amino acids)=268AA_BP= MGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVM TYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQT -------------------------------------------------------------- >26177_26177_3_ELF3-GPR37L1_ELF3_chr1_201980427_ENST00000367284_GPR37L1_chr1_202096869_ENST00000367282_length(transcript)=6213nt_BP=361nt ATGAGACACCAGCTCAGGTTACTGCAGGGGACACACTATAAAGCCCTGAGCTCAGGGAGGAGCTCCCTCCAGGCTCTATTTAGAGCCGGG TAGGGGAGCGCAGCGGCCAGATACCTCAGCGCTACCTGGCGGAACTGGATTTCTCTCCCGCCTGCCGGCCTGCCTGCCACAGCCGGACTC CGCCACTCCGGTAGCCTCATGGCTGCAACCTGTGAGATTAGCAACATTTTTAGCAACTACTTCAGTGCGATGTACAGCTCGGAGGACTCC ACCCTGGCCTCTGTTCCCCCTGCTGCCACCTTTGGGGCCGATGACTTGGTACTGACCCTGAGCAACCCCCAGATGTCATTGGAGGGTACA GGTCTCCTCTCTGGGAGTCACGACTTTCAGCCTCTGTGCCCTGGGCATTGACCGCTTCCACGTGGCCACCAGCACCCTGCCCAAGGTGAG GCCCATCGAGCGGTGCCAATCCATCCTGGCCAAGTTGGCTGTCATCTGGGTGGGCTCCATGACGCTGGCTGTGCCTGAGCTCCTGCTGTG GCAGCTGGCACAGGAGCCTGCCCCCACCATGGGCACCCTGGACTCATGCATCATGAAACCCTCAGCCAGCCTGCCCGAGTCCCTGTATTC ACTGGTGATGACCTACCAGAACGCCCGCATGTGGTGGTACTTTGGCTGCTACTTCTGCCTGCCCATCCTCTTCACAGTCACCTGCCAGCT GGTGACATGGCGGGTGCGAGGCCCTCCAGGGAGGAAGTCAGAGTGCAGGGCCAGCAAGCACGAGCAGTGTGAGAGCCAGCTCAACAGCAC CGTGGTGGGCCTGACCGTGGTCTACGCCTTCTGCACCCTCCCAGAGAACGTCTGCAACATCGTGGTGGCCTACCTCTCCACCGAGCTGAC CCGCCAGACCCTGGACCTCCTGGGCCTCATCAACCAGTTCTCCACCTTCTTCAAGGGCGCCATCACCCCAGTGCTGCTCCTTTGCATCTG CAGGCCGCTGGGCCAGGCCTTCCTGGACTGCTGCTGCTGCTGCTGCTGTGAGGAGTGCGGCGGGGCTTCGGAGGCCTCTGCTGCCAATGG GTCGGACAACAAGCTCAAGACCGAGGTGTCCTCTTCCATCTACTTCCACAAGCCCAGGGAGTCACCCCCACTCCTGCCCCTGGGCACACC TTGCTGAGGCCCCAGTAGGGGTGGGGAGGGAGGGAGAGGCCGCCACCCCCGCCGGTGTCTGCTGTTCTTTCCCCATAGGTCTTGCTTTGT TGCCTGTCTTGCTGTCTAGGGATGGACTTGGTTCCTCTTGTCAAGGTTTGGGAATGTCAAAGCCCCCTCCCCACACAGGGCCTTTCCTGT CCCTTGTGGGGCCTTCCAACCCTGTCCTTTCCACTGGTGGGCGGTGATGCTTCTAGGTCCTTAGAACTGCCCAGAAACTCTGAGTCCCAG CAGCTGGGAGCCAGAACTTTGCCTGCCCTCCCTTGGTTCCAGTCTCTCTTCTCTCTCTCTGCCTTGGAACCTGACCATACTTTAGTTGTG CCCTTCCCAGGCATCATCCTCCTACCACCAACCTGGGGCCCCATCTTGGAATGGGGGCTCCTTGGGGCCAGCCCAGTGTGGCTCACCACA CTCTTCTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTACATTTGCCTGATGTCAGCTCCCTGCAA CCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGTGCACCAACACACCCGGCTAATTTT TGTATTTGTAGAAGAGGCGGGGTTTCACCATGTTGGCCAGGCTGGTGTTGAACTCCTGACCTCAAGTGATCTGCCTGCCTTGGCCTCCCA AAGTGCTGGGATTACAGGTGTGAGCTGCCACGCCCAGCCCCAGTACACTCTTCTCTGGACCAGATCTGTCCCAGTCCTGGATGCCTCCTC CTACTGGTGCCTTCTTTTCTTCCAGAGGATTTCTCTCTCCTTCCTCCTCCTTTCTTTGGGATCCCTGGGTTGCCCTGTCCCAACCTCCTT GTTAGGTGCTTTCCCATAGGAGGCCCTTCTTGAGAAACAATAAACTAGGTAGAACTACCCCTATGCCCATCCACTTTCTTGTGCCACATT CTGGCAGGGCCCAGATGCAGCTGGGCCTTCCTGGCCTGGCAGTGCCTAGGAGAATTTCTCCTGACCTGGCCTGGCCTGTGGCTGATGTTC AGAACAGCCTTGTGGCCGATGTTCAGAACAGCCTTGTGGCCCTGGCGACTCCAAGGGTTTTATGGCTTTTGAGGGACAGAGAGGATGGAG GGCTTGGGGAGCCGGAGGACCTAAGTCCTCATCCTGGCCTAAACCCCATGCTCCTTGGGAAGTCAAAAGCCTGGAAAATATCTCCTCTGG AGCCTTCATCTCTGCTATGCCCTCTCTCCACAAAGCCCCCCTTGGAGGGAGTCCAGTGGTCTTTCCTCTGTGAGCCCCAGGGCTTCCCAG CCTTTGTCACTCTGAGAGCTGCTCTTGTTCAGTTTCTTAGAATGGACTGTTTTGCCTGTAGACGGCCCAGCTGCCTGCCCTGGCCTGCCC CCACCCAGCCCCCACTGCACCACCCTTCCCGCCAGAGCTCCCACTGCCCCCGGCAGACCCTTCATGCAGCTTCTCCTGTGGGGTCTTGCC CTTGAAGTGCCACTTCCCCCAGCCCCACCTCTGGTCCCTTCCAGAGGGCACCCTTAGCCTTGTAGGTCCCTGGGAAGCTGGCACAGCATC AACCAGAAGTGATGCCTCAGCCAGGCCACCAGTCGCTCCCCGCCTGGGAGCTCAGCTTTCCTCAGAACCACCCCCCCTGTCTGAAGCTCT GTCCTGGGTCCCACCAGACTTCTGCCCACCAGGCCTACCTACAGCATCCACATGGGGCCTCAGGAAGGGCCCCGGGGGCCCAGGGATGGG CAGGGGCAGGGTTTCCAAGCGCCTGGGGCTCCATTCTCCTCTGTCCACCCACCCACACCCCTTGGCCTCAGCCTGCCCTGTACCCAAGCT TCCCTCCCCCTCTCCTGGGGATCTTAACGGCCTTGTTCTCTCTCCCTGGCACCCACCCCCAGGGCGGGTGATGCCGCCAAGAGAGAGGGA GGCCGTTGCTAGGTGATGGCGCCGCCATGCACACACCCTTTGTGCTGGGGAGTGACACCCACCCGTTTCTCAGCAGACCTGTTGCCACGG TGACTGAAGCCCCCAGCTCTGTCTGTAGAAACTTCAGATGGGTGGGGGAGCAGGTTGGAGAGGGGACCAAAGGCAGGCCTGTCGTGCTGA AGCTCTTGGGGACCGTTTCCTCGGCATTTCCCCAACTCCTTCTCCACCCCCCTGCCAGGCCCGGAAGTACCACCAGCTTCCTAAGGGATG CAGGAAGGGGCCGGGTGAACTGAGGTGAAGTCCAGGGCAGGGGAGTCAGACCCCTCAACATCCTGTTTAGGGGTCCTCCTCCACAAAGGG TGCCCTCCACCTCTCCCTCCTGCTGGTTGGCCGGCTCAGAGATGAAGGGGGAGAGATGGTGGCTCCAAGGCTCTGCCACCGCCACCTCCC AAGCCTGCCAACGTGAATGGCTTGCAGAATCAGTCAGCAGGCCAGCGGCCTTGGGAAAGAGCCACTGTCCTCGCAGCCTGGGCCAGCTGG GGGAACAATGTAGGGTTTGTTGCTTAGGGGTCCCAGGCTTGCGGGGGGGTTGGCACATGGTGGGCAGTGGACTTGAGCTGGGATGGTCTG AGGGGGCACTGACACGCTCACCCGAGGGCAGACTTCAGACCAGCCCTCAGATCCTGATGCCAGGTTACAGGGCTGAGGGGAGCCTGAAAT CCACTGGGTCTCCCTGCTCCACTTGGGAGTCACCTTCTCATCACCTATCCTGGAACTGAATGCAATTACTTAAACTCAGTCTCAGCTTCC TCATCTGTAAAATGGGAATAATCTGTCCTTCACAGAGGATTATGGTCATTTAATGAGACAAGATACATAAAGCACTTTGCATGGTGCCCC GAACCTTTTATTCCTTCCTCTCCTTTGGGAATTCAATTCTCTAGTGTTAGGAGCAGGCTTGGCCCAGGGATTCTTAAATGCATCCAGGTT TTGGCATCAAAGGGCCCCAAACATGACAATTTACCTATACTCATGGTCTGTTCCCATTCAACTTTAATAGGTTATGTGTGTTTTTTTTTT CTTAAGAGCTGGGTGGGGGGGTCTCACTATGTTGCCCAGGCTGGCTTTGAACTCCTGGGCTCAAGCAGTCCTCCTGTCTCAGCCTCCTGA GTAGCTGGGACTACAAGTGTGTACCACCATGCCTGGCTGAACACTTTTTTTTTTTTGAGACAAGATCCCACTCAGTCACTCAAGCTGAGT GCTGTGGTGTGATCACAGCTCATTGCAGCCTCCACTTCCTGGGCTCAAGCGATTCTCCTGCCTCAGCTTCCTGAGTAGCTGGGACTACAG GTGCGCACTACCACGCCTGTCTAATTTTTGATTATTTGTAGAGATAGGGTCTCACTATTTTGCCCAGGCTGGTCTCAAACTCCCAGACTC AAGTCATTCTCCTACCTCGGGCTCCCAAAGTACTGGGATTACAGGCATGAGCACCTGGCCCCTGAACAAATTCTTTAAGTCATATTAGCA CCTGCTGCACGCCGGCACTGTGGAAGGAGGATGCTTGCTTGCTTCCTGGTAACCAGCTCTCTTATCTCAAACCTCAATCCTCAGTGAGGA TCACAGGATCTGAGAAAGGCACCTTGGCCTGGAAACAGCCCCAGATGAGTGAGATTGCTGGTCCTCTCCCGGGATCCCAGGCCCAGGAAA ACCTAGCCATGCTTGCAGTCAGGAGAGGGCAGGGGATAGAGCCCTGGCTCCCATTCAACCTCCTTAGCCAGGAGGACATGTCCCATTTTG CTTAGGAGTTGGGAGGTACCCTAGAATCACTTAGCTTCAGATGCCAAATTCCATCCACATTCTTTCCTCCAACTCTCTGGCAGTGGGGAA CTGCCTCTCCAGGCAGGGAACTGCTCTGACAGGTCTGATGACTGCCTCCAGGAGGAAGCCCTGGGCACCAATGAAGGTGAGGGGCTGGAG GGCCCAGGACGGGGAGTCAAGGTCCCCACTCCCAGGACTAAGGGACAGTTTGGCTCCTTTTTCCTGCAGTGGGAGGGGTGAGAAGGGCTG GGGTGTTCTGCAAGGGCCTGCTCCATTTTCCAGGGTGAAGGAGAGGCCGAGGGAGGTGGAGCGGGAGGAGGTGGGGCTTACTGTGAAACT GGGTCAAGATGGCCTCGGATTTGAGCAGGCAGGGTCACCAGGCTCTGAGGCAGCAGCTGTGAGCAGTGCCGAGGGAGGACCAGCTCTGAC GGTGAGGTCGGGTGGGGGACTAGAATCCAGCAGAGGAGCGAGGGCAGGGCTCCTACCAGGAAACCCATAGCATTGACACTAACTGAGAGG CAGCAAAGGCGGTGACACTCCCCCAGGCTCTGTGGGCCCAGCCCTACCCCTGAAGCACAGTTAACTGGTTCTGGGGTAGGAACTGGGGGC CGGAGGGACAGGGTTCTGGTTCTGGCTCAACCTTGGCTGCTGGTGAGATCCAGGGCCTGGGAAAGAGGGGCTGAGGCCTGAACTGGGCCT AAGGAGAGTGCAGCTCAGTTCGCACACAACAGCACCCAGCCCTGTCCCCTTGCTGCCTCTACCCAGCCCTGGGCAGTTCCCTCAACAGAG CTCTGCAGCCCCAAGTGGCAGCTGCTGGCTCAAAGCTGGGACTACATGAAAGTCTGAAAAGAGAATGAGAAGGAGGTGGCGCAAGAGCCT GGACGCACGTGTGGGAGGCCGTTTTGTGCAGCGCCATTGTGCTCCCCGGGCGGGCATGTGCTCGCGCTCCGTGGCTCTGTTGGTGCCCAG CGTGCGGGGGTGTGCTGGTGGCCCTGTGGGCCTGTAGGGCAACCCATGCCAACTGCGGAAAAGTAACCAGCACCATACACCCCCCCCAAC ACAAAACTGGTCATTTATTTTTTTTGTTGTCATTGTTATTAGGAAGCAAAAAAATGTACAGTTACAAGAATCATTTTCCAAACAGAGGTT AAATATGAGCTGAAAAGTGTAAAAAAGGAAGAGGAACATCACTTTACAAATCATTAAATTAAACAAATAAACAAACAGAACCCAAAGAAC >26177_26177_3_ELF3-GPR37L1_ELF3_chr1_201980427_ENST00000367284_GPR37L1_chr1_202096869_ENST00000367282_length(amino acids)=268AA_BP= MGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVM TYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQT -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ELF3-GPR37L1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ELF3-GPR37L1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ELF3-GPR37L1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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