FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:AFAP1-KCNIP4 (FusionGDB2 ID:2620)

Fusion Gene Summary for AFAP1-KCNIP4

check button Fusion gene summary
Fusion gene informationFusion gene name: AFAP1-KCNIP4
Fusion gene ID: 2620
HgeneTgene
Gene symbol

AFAP1

KCNIP4

Gene ID

60312

80333

Gene nameactin filament associated protein 1potassium voltage-gated channel interacting protein 4
SynonymsAFAP|AFAP-110|AFAP110CALP|KCHIP4
Cytomap

4p16.1

4p15.31-p15.2

Type of geneprotein-codingprotein-coding
Descriptionactin filament-associated protein 1110 kDa actin filament-associated proteinactin filament-associated protein, 110 kDaKv channel-interacting protein 4Kv channel interacting protein 4a-type potassium channel modulatory protein 4calsenilin-like protein
Modification date2020031320200313
UniProtAcc

Q8N556

Q6PIL6

Ensembl transtripts involved in fusion geneENST00000358461, ENST00000360265, 
ENST00000382543, ENST00000420658, 
ENST00000513842, 		ENST00000359001, 
ENST00000382149, ENST00000382148, 
ENST00000382150, ENST00000382152, 
ENST00000447367, ENST00000509207, 
Fusion gene scores* DoF score11 X 17 X 7=130918 X 13 X 9=2106
# samples 1919
** MAII scorelog2(19/1309*10)=-2.78439377361429
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/2106*10)=-3.47043411269477
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AFAP1 [Title/Abstract] AND KCNIP4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAFAP1(7787921)-KCNIP4(20731752), # samples:2
Anticipated loss of major functional domain due to fusion event.AFAP1-KCNIP4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AFAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KCNIP4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1562-01AAFAP1chr4

7783103

-KCNIP4chr4

20731752

-
ChimerDB4OVTCGA-24-1562-01AAFAP1chr4

7787921

-KCNIP4chr4

20731752

-
ChimerDB4OVTCGA-24-1562AFAP1chr4

7787920

-KCNIP4chr4

20731752

-


Top

Fusion Gene ORF analysis for AFAP1-KCNIP4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000358461ENST00000359001AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000358461ENST00000359001AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000358461ENST00000382149AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000358461ENST00000382149AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000360265ENST00000359001AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000360265ENST00000359001AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000360265ENST00000382149AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000360265ENST00000382149AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000382543ENST00000359001AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000382543ENST00000359001AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000382543ENST00000359001AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000382543ENST00000382149AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000382543ENST00000382149AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000382543ENST00000382149AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000420658ENST00000359001AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000420658ENST00000359001AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000420658ENST00000359001AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000420658ENST00000382149AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000420658ENST00000382149AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5CDS-5UTRENST00000420658ENST00000382149AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382148AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382148AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382148AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382150AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382150AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382150AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382152AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382152AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000382152AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000447367AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000447367AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000447367AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000509207AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000509207AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5UTR-3CDSENST00000513842ENST00000509207AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5UTR-5UTRENST00000513842ENST00000359001AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5UTR-5UTRENST00000513842ENST00000359001AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5UTR-5UTRENST00000513842ENST00000359001AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
5UTR-5UTRENST00000513842ENST00000382149AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
5UTR-5UTRENST00000513842ENST00000382149AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
5UTR-5UTRENST00000513842ENST00000382149AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000382148AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000382148AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000382150AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000382150AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000382152AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000382152AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000447367AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000358461ENST00000447367AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000382148AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000382148AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000382150AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000382150AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000382152AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000382152AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000447367AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000360265ENST00000447367AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382148AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382148AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382148AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382150AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382150AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382150AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382152AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382152AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000382152AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000447367AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000447367AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000382543ENST00000447367AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382148AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382148AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382148AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382150AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382150AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382150AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382152AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382152AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000382152AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000447367AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000447367AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
Frame-shiftENST00000420658ENST00000447367AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
In-frameENST00000358461ENST00000509207AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
In-frameENST00000358461ENST00000509207AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
In-frameENST00000360265ENST00000509207AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
In-frameENST00000360265ENST00000509207AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
In-frameENST00000382543ENST00000509207AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
In-frameENST00000382543ENST00000509207AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
In-frameENST00000382543ENST00000509207AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
In-frameENST00000420658ENST00000509207AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
In-frameENST00000420658ENST00000509207AFAP1chr4

7787921

-KCNIP4chr4

20731752

-
In-frameENST00000420658ENST00000509207AFAP1chr4

7787920

-KCNIP4chr4

20731752

-
intron-3CDSENST00000358461ENST00000382148AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000358461ENST00000382150AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000358461ENST00000382152AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000358461ENST00000447367AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000358461ENST00000509207AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000360265ENST00000382148AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000360265ENST00000382150AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000360265ENST00000382152AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000360265ENST00000447367AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-3CDSENST00000360265ENST00000509207AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-5UTRENST00000358461ENST00000359001AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-5UTRENST00000358461ENST00000382149AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-5UTRENST00000360265ENST00000359001AFAP1chr4

7783103

-KCNIP4chr4

20731752

-
intron-5UTRENST00000360265ENST00000382149AFAP1chr4

7783103

-KCNIP4chr4

20731752

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000360265AFAP1chr47787921-ENST00000509207KCNIP4chr420731752-225717651871812541
ENST00000358461AFAP1chr47787921-ENST00000509207KCNIP4chr420731752-229518032731850525
ENST00000420658AFAP1chr47787921-ENST00000509207KCNIP4chr420731752-229518032731850525
ENST00000382543AFAP1chr47787921-ENST00000509207KCNIP4chr420731752-2026153441581525
ENST00000360265AFAP1chr47787920-ENST00000509207KCNIP4chr420731752-225717651871812541
ENST00000358461AFAP1chr47787920-ENST00000509207KCNIP4chr420731752-229518032731850525
ENST00000420658AFAP1chr47787920-ENST00000509207KCNIP4chr420731752-229518032731850525
ENST00000382543AFAP1chr47787920-ENST00000509207KCNIP4chr420731752-2026153441581525
ENST00000420658AFAP1chr47783103-ENST00000509207KCNIP4chr420731752-254720552732102609
ENST00000382543AFAP1chr47783103-ENST00000509207KCNIP4chr420731752-2278178641833609

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000360265ENST00000509207AFAP1chr47787921-KCNIP4chr420731752-0.0025679620.99743205
ENST00000358461ENST00000509207AFAP1chr47787921-KCNIP4chr420731752-0.003273410.9967265
ENST00000420658ENST00000509207AFAP1chr47787921-KCNIP4chr420731752-0.003273410.9967265
ENST00000382543ENST00000509207AFAP1chr47787921-KCNIP4chr420731752-0.0028038940.9971961
ENST00000360265ENST00000509207AFAP1chr47787920-KCNIP4chr420731752-0.0025679620.99743205
ENST00000358461ENST00000509207AFAP1chr47787920-KCNIP4chr420731752-0.003273410.9967265
ENST00000420658ENST00000509207AFAP1chr47787920-KCNIP4chr420731752-0.003273410.9967265
ENST00000382543ENST00000509207AFAP1chr47787920-KCNIP4chr420731752-0.0028038940.9971961
ENST00000420658ENST00000509207AFAP1chr47783103-KCNIP4chr420731752-0.0048942860.99510574
ENST00000382543ENST00000509207AFAP1chr47783103-KCNIP4chr420731752-0.0041261790.99587387

Top

Fusion Genomic Features for AFAP1-KCNIP4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for AFAP1-KCNIP4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:7787921/chr4:20731752)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AFAP1

Q8N556

KCNIP4

Q6PIL6

FUNCTION: Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells. {ECO:0000250, ECO:0000269|PubMed:15485829}.FUNCTION: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. {ECO:0000250|UniProtKB:Q6PHZ8, ECO:0000269|PubMed:11847232, ECO:0000269|PubMed:18957440, ECO:0000269|PubMed:23576435}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-121760_106594815.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-131860_106594815.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-121760_106510731.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-111660_106510731.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-111760_106510815.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-121860_106510815.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-121760_106510731.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-111660_106510731.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-111760_106510815.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-121860_106510815.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-1217153_249594815.0DomainPH 1
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-1217347_441594815.0DomainPH 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-1318153_249594815.0DomainPH 1
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-1318347_441594815.0DomainPH 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-1217153_249510731.0DomainPH 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-1217347_441510731.0DomainPH 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-1116153_249510731.0DomainPH 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-1116347_441510731.0DomainPH 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-1117153_249510815.0DomainPH 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-1117347_441510815.0DomainPH 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-1218153_249510815.0DomainPH 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-1218347_441510815.0DomainPH 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-1217153_249510731.0DomainPH 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-1217347_441510731.0DomainPH 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-1116153_249510731.0DomainPH 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-1116347_441510731.0DomainPH 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-1117153_249510815.0DomainPH 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-1117347_441510815.0DomainPH 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-1218153_249510815.0DomainPH 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-1218347_441510815.0DomainPH 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-1217451_456594815.0MotifSH2-binding 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-121771_74594815.0MotifSH3-binding
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-121794_97594815.0MotifSH2-binding 1
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-1318451_456594815.0MotifSH2-binding 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-131871_74594815.0MotifSH3-binding
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-131894_97594815.0MotifSH2-binding 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-1217451_456510731.0MotifSH2-binding 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-121771_74510731.0MotifSH3-binding
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-121794_97510731.0MotifSH2-binding 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-1116451_456510731.0MotifSH2-binding 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-111671_74510731.0MotifSH3-binding
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-111694_97510731.0MotifSH2-binding 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-1117451_456510815.0MotifSH2-binding 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-111771_74510815.0MotifSH3-binding
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-111794_97510815.0MotifSH2-binding 1
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-1218451_456510815.0MotifSH2-binding 2
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-121871_74510815.0MotifSH3-binding
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-121894_97510815.0MotifSH2-binding 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-1217451_456510731.0MotifSH2-binding 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-121771_74510731.0MotifSH3-binding
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-121794_97510731.0MotifSH2-binding 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-1116451_456510731.0MotifSH2-binding 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-111671_74510731.0MotifSH3-binding
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-111694_97510731.0MotifSH2-binding 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-1117451_456510815.0MotifSH2-binding 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-111771_74510815.0MotifSH3-binding
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-111794_97510815.0MotifSH2-binding 1
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-1218451_456510815.0MotifSH2-binding 2
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-121871_74510815.0MotifSH3-binding
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-121894_97510815.0MotifSH2-binding 1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000035900168217_228173189.0Calcium binding3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038214868217_228210226.0Calcium binding3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215068217_228214230.0Calcium binding3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000044736768217_228201217.0Calcium binding3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000050920768217_228173189.0Calcium binding3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000035900168217_228173189.0Calcium binding3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038214868217_228210226.0Calcium binding3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215068217_228214230.0Calcium binding3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000044736768217_228201217.0Calcium binding3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000050920768217_228173189.0Calcium binding3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000035900168217_228173189.0Calcium binding3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038214868217_228210226.0Calcium binding3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215068217_228214230.0Calcium binding3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000044736768217_228201217.0Calcium binding3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000050920768217_228173189.0Calcium binding3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000035900168204_239173189.0DomainEF-hand 4
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000044736768204_239201217.0DomainEF-hand 4
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000050920768204_239173189.0DomainEF-hand 4
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000035900168204_239173189.0DomainEF-hand 4
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000044736768204_239201217.0DomainEF-hand 4
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000050920768204_239173189.0DomainEF-hand 4
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000035900168204_239173189.0DomainEF-hand 4
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000044736768204_239201217.0DomainEF-hand 4
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000050920768204_239173189.0DomainEF-hand 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-117557_6480731.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-116557_6480731.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-1217557_648594815.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-1318557_648594815.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-1217557_648510731.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-1116557_648510731.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-1117557_648510815.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-1218557_648510815.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-1217557_648510731.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-1116557_648510731.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-1117557_648510815.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-1218557_648510815.0Coiled coilOntology_term=ECO:0000255
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-11760_1060731.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-11660_1060731.0Compositional biasNote=Pro-rich
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-117153_2490731.0DomainPH 1
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-117347_4410731.0DomainPH 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-116153_2490731.0DomainPH 1
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-116347_4410731.0DomainPH 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-117451_4560731.0MotifSH2-binding 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-11771_740731.0MotifSH3-binding
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-11794_970731.0MotifSH2-binding 1
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-116451_4560731.0MotifSH2-binding 2
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-11671_740731.0MotifSH3-binding
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-11694_970731.0MotifSH2-binding 1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000035900168133_144173189.0Calcium binding1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000035900168169_180173189.0Calcium binding2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038214868133_144210226.0Calcium binding1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038214868169_180210226.0Calcium binding2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215068133_144214230.0Calcium binding1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215068169_180214230.0Calcium binding2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215279133_144235251.0Calcium binding1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215279169_180235251.0Calcium binding2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215279217_228235251.0Calcium binding3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000044736768133_144201217.0Calcium binding1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000044736768169_180201217.0Calcium binding2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000050920768133_144173189.0Calcium binding1
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000050920768169_180173189.0Calcium binding2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000035900168133_144173189.0Calcium binding1
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000035900168169_180173189.0Calcium binding2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038214868133_144210226.0Calcium binding1
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038214868169_180210226.0Calcium binding2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215068133_144214230.0Calcium binding1
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215068169_180214230.0Calcium binding2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215279133_144235251.0Calcium binding1
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215279169_180235251.0Calcium binding2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215279217_228235251.0Calcium binding3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000044736768133_144201217.0Calcium binding1
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000044736768169_180201217.0Calcium binding2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000050920768133_144173189.0Calcium binding1
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000050920768169_180173189.0Calcium binding2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000035900168133_144173189.0Calcium binding1
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000035900168169_180173189.0Calcium binding2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038214868133_144210226.0Calcium binding1
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038214868169_180210226.0Calcium binding2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215068133_144214230.0Calcium binding1
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215068169_180214230.0Calcium binding2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215279133_144235251.0Calcium binding1
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215279169_180235251.0Calcium binding2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215279217_228235251.0Calcium binding3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000044736768133_144201217.0Calcium binding1
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000044736768169_180201217.0Calcium binding2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000050920768133_144173189.0Calcium binding1
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000050920768169_180173189.0Calcium binding2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000035900168120_155173189.0DomainEF-hand 2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000035900168156_191173189.0DomainEF-hand 3
TgeneKCNIP4chr4:7783103chr4:20731752ENST000003590016861_117173189.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038214868120_155210226.0DomainEF-hand 2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038214868156_191210226.0DomainEF-hand 3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038214868204_239210226.0DomainEF-hand 4
TgeneKCNIP4chr4:7783103chr4:20731752ENST000003821486861_117210226.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215068120_155214230.0DomainEF-hand 2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215068156_191214230.0DomainEF-hand 3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215068204_239214230.0DomainEF-hand 4
TgeneKCNIP4chr4:7783103chr4:20731752ENST000003821506861_117214230.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215279120_155235251.0DomainEF-hand 2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215279156_191235251.0DomainEF-hand 3
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215279204_239235251.0DomainEF-hand 4
TgeneKCNIP4chr4:7783103chr4:20731752ENST000003821527961_117235251.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000044736768120_155201217.0DomainEF-hand 2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000044736768156_191201217.0DomainEF-hand 3
TgeneKCNIP4chr4:7783103chr4:20731752ENST000004473676861_117201217.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000050920768120_155173189.0DomainEF-hand 2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000050920768156_191173189.0DomainEF-hand 3
TgeneKCNIP4chr4:7783103chr4:20731752ENST000005092076861_117173189.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000035900168120_155173189.0DomainEF-hand 2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000035900168156_191173189.0DomainEF-hand 3
TgeneKCNIP4chr4:7787920chr4:20731752ENST000003590016861_117173189.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038214868120_155210226.0DomainEF-hand 2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038214868156_191210226.0DomainEF-hand 3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038214868204_239210226.0DomainEF-hand 4
TgeneKCNIP4chr4:7787920chr4:20731752ENST000003821486861_117210226.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215068120_155214230.0DomainEF-hand 2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215068156_191214230.0DomainEF-hand 3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215068204_239214230.0DomainEF-hand 4
TgeneKCNIP4chr4:7787920chr4:20731752ENST000003821506861_117214230.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215279120_155235251.0DomainEF-hand 2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215279156_191235251.0DomainEF-hand 3
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215279204_239235251.0DomainEF-hand 4
TgeneKCNIP4chr4:7787920chr4:20731752ENST000003821527961_117235251.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000044736768120_155201217.0DomainEF-hand 2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000044736768156_191201217.0DomainEF-hand 3
TgeneKCNIP4chr4:7787920chr4:20731752ENST000004473676861_117201217.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000050920768120_155173189.0DomainEF-hand 2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000050920768156_191173189.0DomainEF-hand 3
TgeneKCNIP4chr4:7787920chr4:20731752ENST000005092076861_117173189.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000035900168120_155173189.0DomainEF-hand 2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000035900168156_191173189.0DomainEF-hand 3
TgeneKCNIP4chr4:7787921chr4:20731752ENST000003590016861_117173189.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038214868120_155210226.0DomainEF-hand 2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038214868156_191210226.0DomainEF-hand 3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038214868204_239210226.0DomainEF-hand 4
TgeneKCNIP4chr4:7787921chr4:20731752ENST000003821486861_117210226.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215068120_155214230.0DomainEF-hand 2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215068156_191214230.0DomainEF-hand 3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215068204_239214230.0DomainEF-hand 4
TgeneKCNIP4chr4:7787921chr4:20731752ENST000003821506861_117214230.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215279120_155235251.0DomainEF-hand 2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215279156_191235251.0DomainEF-hand 3
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215279204_239235251.0DomainEF-hand 4
TgeneKCNIP4chr4:7787921chr4:20731752ENST000003821527961_117235251.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000044736768120_155201217.0DomainEF-hand 2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000044736768156_191201217.0DomainEF-hand 3
TgeneKCNIP4chr4:7787921chr4:20731752ENST000004473676861_117201217.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000050920768120_155173189.0DomainEF-hand 2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000050920768156_191173189.0DomainEF-hand 3
TgeneKCNIP4chr4:7787921chr4:20731752ENST000005092076861_117173189.0DomainEF-hand 1%3B degenerate
TgeneKCNIP4chr4:7783103chr4:20731752ENST00000359001682_44173189.0RegionKIS
TgeneKCNIP4chr4:7783103chr4:20731752ENST00000382148682_44210226.0RegionKIS
TgeneKCNIP4chr4:7783103chr4:20731752ENST00000382150682_44214230.0RegionKIS
TgeneKCNIP4chr4:7783103chr4:20731752ENST00000382152792_44235251.0RegionKIS
TgeneKCNIP4chr4:7783103chr4:20731752ENST00000447367682_44201217.0RegionKIS
TgeneKCNIP4chr4:7783103chr4:20731752ENST00000509207682_44173189.0RegionKIS
TgeneKCNIP4chr4:7787920chr4:20731752ENST00000359001682_44173189.0RegionKIS
TgeneKCNIP4chr4:7787920chr4:20731752ENST00000382148682_44210226.0RegionKIS
TgeneKCNIP4chr4:7787920chr4:20731752ENST00000382150682_44214230.0RegionKIS
TgeneKCNIP4chr4:7787920chr4:20731752ENST00000382152792_44235251.0RegionKIS
TgeneKCNIP4chr4:7787920chr4:20731752ENST00000447367682_44201217.0RegionKIS
TgeneKCNIP4chr4:7787920chr4:20731752ENST00000509207682_44173189.0RegionKIS
TgeneKCNIP4chr4:7787921chr4:20731752ENST00000359001682_44173189.0RegionKIS
TgeneKCNIP4chr4:7787921chr4:20731752ENST00000382148682_44210226.0RegionKIS
TgeneKCNIP4chr4:7787921chr4:20731752ENST00000382150682_44214230.0RegionKIS
TgeneKCNIP4chr4:7787921chr4:20731752ENST00000382152792_44235251.0RegionKIS
TgeneKCNIP4chr4:7787921chr4:20731752ENST00000447367682_44201217.0RegionKIS
TgeneKCNIP4chr4:7787921chr4:20731752ENST00000509207682_44173189.0RegionKIS


Top

Fusion Gene Sequence for AFAP1-KCNIP4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2620_2620_1_AFAP1-KCNIP4_AFAP1_chr4_7783103_ENST00000382543_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2278nt_BP=1786nt
AGCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGC
AGTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCT
GCCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCT
CCCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAG
CAGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGA
CCTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACAC
CAAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGA
CAGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCA
GTGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAA
GGCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAA
GGAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAG
TCTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAA
CAGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTC
TATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGC
AGTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCT
GCACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATC
TGCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGG
CTCGTGGGAACCGGAAGACGGCTTTCCTGCTTCCTGCAGCAGAGGCTTGGGAGAAGAGGTGCTTTATGATAACGCAGGCCTGTACGATAA
CTTGCCGCCTCCGCACATCTTTGCCCGCTACTCTCCTGCTGACAGAAAGGCCTCTAGGCTGTCTGCTGACAAGCTGTCCTCTAACCATTA
CAAATACCCTGCCTCCGCTCAGTCTGTCACTAATACCTCTTCTGTGGGGAGGGCGTCTCTCGGGCTCAACTCGCAGGATGAAAACATAAT
GCGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAACTATTCTACCACCCTTA
AAGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTTTTAATATAAAGCAATCC
CCAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAACTCATTTCATACTCTGT
GAATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCACATATCAGTGATTTTAA
AATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGACATCTGCATTTAATTTC

>2620_2620_1_AFAP1-KCNIP4_AFAP1_chr4_7783103_ENST00000382543_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=609AA_BP=593
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH
YDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSWEPEDGFPASCSRGLGEEVLYDNAGLYDNL

--------------------------------------------------------------
>2620_2620_2_AFAP1-KCNIP4_AFAP1_chr4_7783103_ENST00000420658_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2547nt_BP=2055nt
GGGCGCCCGGCTCCGCTGGGGGCGGGACGGCGGGCGGCGGGCGGGGCCGTGTGCGCCTGCGTGGTGTCTGTCCCGGCCGCAGCCCCACGC
CGGCTGCAGCTCCGCGAGCCGAGCCGGATCTCGAGCGGGGTACACGGGCTGAGGCGGCGGCGGCGGCCCCGCCCCGGGGCTCCATTGTTA
AGGCGGCTGCGGCTCTGTCGGCTGTTCAGCTGCGCTCCAGTCGGCCCAGGCGCCGCGGCGAGGAGCGAGCGCTGCGAGGTGGCGGCCTGA
GCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGCA
GTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCTG
CCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCTC
CCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAGC
AGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGAC
CTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACACC
AAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGAC
AGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCAG
TGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAAG
GCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAAG
GAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAGT
CTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAAC
AGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTCT
ATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGCA
GTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCTG
CACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATCT
GCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGGC
TCGTGGGAACCGGAAGACGGCTTTCCTGCTTCCTGCAGCAGAGGCTTGGGAGAAGAGGTGCTTTATGATAACGCAGGCCTGTACGATAAC
TTGCCGCCTCCGCACATCTTTGCCCGCTACTCTCCTGCTGACAGAAAGGCCTCTAGGCTGTCTGCTGACAAGCTGTCCTCTAACCATTAC
AAATACCCTGCCTCCGCTCAGTCTGTCACTAATACCTCTTCTGTGGGGAGGGCGTCTCTCGGGCTCAACTCGCAGGATGAAAACATAATG
CGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAACTATTCTACCACCCTTAA
AGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTTTTAATATAAAGCAATCCC
CAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAACTCATTTCATACTCTGTG
AATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCACATATCAGTGATTTTAAA
ATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGACATCTGCATTTAATTTCC

>2620_2620_2_AFAP1-KCNIP4_AFAP1_chr4_7783103_ENST00000420658_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=609AA_BP=593
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH
YDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSWEPEDGFPASCSRGLGEEVLYDNAGLYDNL

--------------------------------------------------------------
>2620_2620_3_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000358461_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2295nt_BP=1803nt
GGGCGCCCGGCTCCGCTGGGGGCGGGACGGCGGGCGGCGGGCGGGGCCGTGTGCGCCTGCGTGGTGTCTGTCCCGGCCGCAGCCCCACGC
CGGCTGCAGCTCCGCGAGCCGAGCCGGATCTCGAGCGGGGTACACGGGCTGAGGCGGCGGCGGCGGCCCCGCCCCGGGGCTCCATTGTTA
AGGCGGCTGCGGCTCTGTCGGCTGTTCAGCTGCGCTCCAGTCGGCCCAGGCGCCGCGGCGAGGAGCGAGCGCTGCGAGGTGGCGGCCTGA
GCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGCA
GTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCTG
CCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCTC
CCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAGC
AGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGAC
CTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACACC
AAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGAC
AGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCAG
TGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAAG
GCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAAG
GAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAGT
CTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAAC
AGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTCT
ATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGCA
GTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCTG
CACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATCT
GCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGGC
TCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAA
CTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTT
TTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAA
CTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCA
CATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGA

>2620_2620_3_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000358461_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=525AA_BP=510
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH

--------------------------------------------------------------
>2620_2620_4_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000360265_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2257nt_BP=1765nt
CTCCCAGTTGAATTTTGCTGCCTTAAAGCAGAAGCAAAGGAGTAGTGCATTTGTTAAGAAGAAGACGCCTGAATCTTTTAGTGGACCTGC
TTTCAGCAAACTTGTTTTTTAGGTCAGAATACTATATCCAATGATCAAGCTAAACATGAAATGCTTCGAGTAAGACTCAGTATTCATACT
TTGACATTTGCAAATCACTGGGTCTAATAATACTCTTCCTCTTTTGTTGTCAGCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCT
TGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGCAGTGATAACCAACATTCTGCTAAGAATACAGTCATCCAA
AGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCTGCCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCA
GCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCTCCCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCC
CGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAGCAGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGG
GAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGACCTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCG
GAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACACCAAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCC
TCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGACAGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCA
GGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCAGTGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAG
TGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAAGGCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAG
CTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAAGGAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGC
CAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAGTCTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTC
CTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAACAGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAA
CAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTCTATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGA
TTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGCAGTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTG
GATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCTGCACTATGACTACATTGATGTGGAGATGTCTGCAAGTGT
CATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATCTGCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGC
CCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGGCTCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGA
AAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAACTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTA
GCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTTTTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAG
TTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAACTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAA
TCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCACATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTAC
TCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGACATCTGCATTTAATTTCCAGAAATTAAATTAATTTTCA

>2620_2620_4_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000360265_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=541AA_BP=526
MQITGSNNTLPLLLSAMEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPW
LPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKK
RFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGP
VDSECPPPPSSPVHKAELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSA
EEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIG
ILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSDENIMRSMQLFENV

--------------------------------------------------------------
>2620_2620_5_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000382543_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2026nt_BP=1534nt
AGCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGC
AGTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCT
GCCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCT
CCCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAG
CAGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGA
CCTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACAC
CAAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGA
CAGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCA
GTGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAA
GGCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAA
GGAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAG
TCTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAA
CAGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTC
TATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGC
AGTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCT
GCACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATC
TGCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGG
CTCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGA
ACTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGT
TTTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTA
ACTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTC
ACATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTG

>2620_2620_5_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000382543_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=525AA_BP=510
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH

--------------------------------------------------------------
>2620_2620_6_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000420658_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2295nt_BP=1803nt
GGGCGCCCGGCTCCGCTGGGGGCGGGACGGCGGGCGGCGGGCGGGGCCGTGTGCGCCTGCGTGGTGTCTGTCCCGGCCGCAGCCCCACGC
CGGCTGCAGCTCCGCGAGCCGAGCCGGATCTCGAGCGGGGTACACGGGCTGAGGCGGCGGCGGCGGCCCCGCCCCGGGGCTCCATTGTTA
AGGCGGCTGCGGCTCTGTCGGCTGTTCAGCTGCGCTCCAGTCGGCCCAGGCGCCGCGGCGAGGAGCGAGCGCTGCGAGGTGGCGGCCTGA
GCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGCA
GTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCTG
CCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCTC
CCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAGC
AGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGAC
CTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACACC
AAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGAC
AGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCAG
TGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAAG
GCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAAG
GAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAGT
CTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAAC
AGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTCT
ATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGCA
GTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCTG
CACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATCT
GCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGGC
TCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAA
CTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTT
TTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAA
CTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCA
CATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGA

>2620_2620_6_AFAP1-KCNIP4_AFAP1_chr4_7787920_ENST00000420658_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=525AA_BP=510
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH

--------------------------------------------------------------
>2620_2620_7_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000358461_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2295nt_BP=1803nt
GGGCGCCCGGCTCCGCTGGGGGCGGGACGGCGGGCGGCGGGCGGGGCCGTGTGCGCCTGCGTGGTGTCTGTCCCGGCCGCAGCCCCACGC
CGGCTGCAGCTCCGCGAGCCGAGCCGGATCTCGAGCGGGGTACACGGGCTGAGGCGGCGGCGGCGGCCCCGCCCCGGGGCTCCATTGTTA
AGGCGGCTGCGGCTCTGTCGGCTGTTCAGCTGCGCTCCAGTCGGCCCAGGCGCCGCGGCGAGGAGCGAGCGCTGCGAGGTGGCGGCCTGA
GCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGCA
GTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCTG
CCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCTC
CCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAGC
AGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGAC
CTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACACC
AAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGAC
AGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCAG
TGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAAG
GCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAAG
GAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAGT
CTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAAC
AGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTCT
ATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGCA
GTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCTG
CACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATCT
GCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGGC
TCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAA
CTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTT
TTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAA
CTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCA
CATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGA

>2620_2620_7_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000358461_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=525AA_BP=510
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH

--------------------------------------------------------------
>2620_2620_8_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000360265_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2257nt_BP=1765nt
CTCCCAGTTGAATTTTGCTGCCTTAAAGCAGAAGCAAAGGAGTAGTGCATTTGTTAAGAAGAAGACGCCTGAATCTTTTAGTGGACCTGC
TTTCAGCAAACTTGTTTTTTAGGTCAGAATACTATATCCAATGATCAAGCTAAACATGAAATGCTTCGAGTAAGACTCAGTATTCATACT
TTGACATTTGCAAATCACTGGGTCTAATAATACTCTTCCTCTTTTGTTGTCAGCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCT
TGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGCAGTGATAACCAACATTCTGCTAAGAATACAGTCATCCAA
AGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCTGCCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCA
GCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCTCCCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCC
CGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAGCAGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGG
GAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGACCTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCG
GAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACACCAAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCC
TCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGACAGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCA
GGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCAGTGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAG
TGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAAGGCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAG
CTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAAGGAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGC
CAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAGTCTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTC
CTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAACAGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAA
CAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTCTATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGA
TTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGCAGTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTG
GATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCTGCACTATGACTACATTGATGTGGAGATGTCTGCAAGTGT
CATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATCTGCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGC
CCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGGCTCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGA
AAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAACTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTA
GCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTTTTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAG
TTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAACTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAA
TCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCACATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTAC
TCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGACATCTGCATTTAATTTCCAGAAATTAAATTAATTTTCA

>2620_2620_8_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000360265_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=541AA_BP=526
MQITGSNNTLPLLLSAMEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPW
LPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKK
RFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGP
VDSECPPPPSSPVHKAELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSA
EEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIG
ILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSDENIMRSMQLFENV

--------------------------------------------------------------
>2620_2620_9_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000382543_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2026nt_BP=1534nt
AGCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGC
AGTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCT
GCCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCT
CCCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAG
CAGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGA
CCTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACAC
CAAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGA
CAGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCA
GTGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAA
GGCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAA
GGAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAG
TCTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAA
CAGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTC
TATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGC
AGTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCT
GCACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATC
TGCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGG
CTCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGA
ACTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGT
TTTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTA
ACTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTC
ACATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTG

>2620_2620_9_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000382543_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=525AA_BP=510
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH

--------------------------------------------------------------
>2620_2620_10_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000420658_KCNIP4_chr4_20731752_ENST00000509207_length(transcript)=2295nt_BP=1803nt
GGGCGCCCGGCTCCGCTGGGGGCGGGACGGCGGGCGGCGGGCGGGGCCGTGTGCGCCTGCGTGGTGTCTGTCCCGGCCGCAGCCCCACGC
CGGCTGCAGCTCCGCGAGCCGAGCCGGATCTCGAGCGGGGTACACGGGCTGAGGCGGCGGCGGCGGCCCCGCCCCGGGGCTCCATTGTTA
AGGCGGCTGCGGCTCTGTCGGCTGTTCAGCTGCGCTCCAGTCGGCCCAGGCGCCGCGGCGAGGAGCGAGCGCTGCGAGGTGGCGGCCTGA
GCAATGGAAGAGTTAATAGTTGAACTTCGTCTCTTTCTTGAACTCCTGGACCATGAATATCTAACCTCAACTGTCAGGGAGAAAAAGGCA
GTGATAACCAACATTCTGCTAAGAATACAGTCATCCAAAGGTTTTGATGTGAAGGACCATGCTCAGAAGCAGGAGACCGCTAACAGCCTG
CCAGCCCCTCCTCAGATGCCCCTGCCGGAGATCCCTCAGCCCTGGCTGCCTCCTGACAGTGGGCCTCCACCATTGCCAACATCCTCCCTC
CCAGAAGGTTATTATGAGGAAGCTGTGCCGCTGAGCCCCGGAAAAGCTCCGGAATACATCACATCAAATTATGATTCCGATGCGATGAGC
AGCTCTTATGAGTCGTATGATGAAGAGGAGGAGGATGGGAAGGGGAAGAAAACCCGGCACCAGTGGCCCTCCGAGGAGGCCTCCATGGAC
CTGGTCAAGGACGCCAAAATCTGCGCCTTCCTGCTGCGGAAGAAGCGGTTCGGCCAGTGGACCAAGTTGCTCTGCGTCATCAAAGACACC
AAACTGCTGTGCTATAAAAGTTCCAAGGACCAGCAGCCTCAGATGGAACTGCCACTCCAAGGCTGTAACATTACGTACATCCCGAAAGAC
AGCAAAAAGAAGAAGCACGAGCTGAAGATTACTCAGCAGGGCACGGACCCGCTTGTTCTCGCCGTCCAGAGCAAGGAACAGGCCGAGCAG
TGGCTGAAGGTGATCAAAGAAGCCTACAGTGGTTGTAGTGGCCCCGTGGATTCAGAGTGTCCTCCTCCACCAAGCTCCCCGGTGCACAAG
GCAGAACTGGAGAAGAAACTGTCTTCAGAGAGACCCAGCTCAGATGGGGAGGGTGTTGTGGAAAATGGAATTACCACATGTAATGGAAAG
GAGCAAGTGAAGAGGAAGAAAAGTTCCAAATCAGAGGCCAAGGGCACTGTGTCGAAAGTCACTGGGAAAAAAATCACCAAGATCATCAGT
CTGGGAAAGAAAAAGCCGTCCACAGACGAGCAGACCTCCTCAGCTGAGGAAGATGTTCCCACCTGCGGCTATCTGAACGTGCTCTCCAAC
AGCCGCTGGCGAGAGCGCTGGTGCCGAGTGAAAGATAACAAGCTCATTTTCCACAAGGACAGGACCGACCTGAAGACCCATATTGTGTCT
ATTCCGCTCCGTGGCTGCGAGGTGATCCCGGGTTTGGATTCTAAACATCCTCTGACGTTCCGGCTGCTGCGCAACGGCCAGGAGGTTGCA
GTATTGGAGGCATCTTCTTCTGAAGACATGGGCAGGTGGATTGGGATTTTACTCGCAGAGACGGGATCGTCCACAGACCCGGAGGCTCTG
CACTATGACTACATTGATGTGGAGATGTCTGCAAGTGTCATTCAGACAGCCAAACAGACCTTCTGTTTCATGAACAGGCGTGTTATATCT
GCTAACCCATATCTAGGGGGCACCTCCAACGGCTATGCCCACCCCAGCGGGACGGCACTTCATTATGACGATGTCCCGTGCATCAACGGC
TCGGATGAAAACATAATGCGCTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGACAAATGTGAA
CTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCTCAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTT
TTAATATAAAGCAATCCCCAAAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGGGATGGTCTAA
CTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAGTTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCA
CATATCAGTGATTTTAAAATATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCTAATATAGTGA

>2620_2620_10_AFAP1-KCNIP4_AFAP1_chr4_7787921_ENST00000420658_KCNIP4_chr4_20731752_ENST00000509207_length(amino acids)=525AA_BP=510
MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLP
EGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKA
ELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALH

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for AFAP1-KCNIP4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000035900168237_250173.0189.0KCND2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038214868237_250210.0226.0KCND2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215068237_250214.0230.0KCND2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000038215279237_250235.0251.0KCND2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000044736768237_250201.0217.0KCND2
TgeneKCNIP4chr4:7783103chr4:20731752ENST0000050920768237_250173.0189.0KCND2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000035900168237_250173.0189.0KCND2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038214868237_250210.0226.0KCND2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215068237_250214.0230.0KCND2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000038215279237_250235.0251.0KCND2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000044736768237_250201.0217.0KCND2
TgeneKCNIP4chr4:7787920chr4:20731752ENST0000050920768237_250173.0189.0KCND2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000035900168237_250173.0189.0KCND2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038214868237_250210.0226.0KCND2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215068237_250214.0230.0KCND2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000038215279237_250235.0251.0KCND2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000044736768237_250201.0217.0KCND2
TgeneKCNIP4chr4:7787921chr4:20731752ENST0000050920768237_250173.0189.0KCND2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneAFAP1chr4:7783103chr4:20731752ENST00000358461-117594_6370731.0F-actin
HgeneAFAP1chr4:7783103chr4:20731752ENST00000360265-116594_6370731.0F-actin
HgeneAFAP1chr4:7783103chr4:20731752ENST00000382543-1217594_637594.0815.0F-actin
HgeneAFAP1chr4:7783103chr4:20731752ENST00000420658-1318594_637594.0815.0F-actin
HgeneAFAP1chr4:7787920chr4:20731752ENST00000358461-1217594_637510.0731.0F-actin
HgeneAFAP1chr4:7787920chr4:20731752ENST00000360265-1116594_637510.0731.0F-actin
HgeneAFAP1chr4:7787920chr4:20731752ENST00000382543-1117594_637510.0815.0F-actin
HgeneAFAP1chr4:7787920chr4:20731752ENST00000420658-1218594_637510.0815.0F-actin
HgeneAFAP1chr4:7787921chr4:20731752ENST00000358461-1217594_637510.0731.0F-actin
HgeneAFAP1chr4:7787921chr4:20731752ENST00000360265-1116594_637510.0731.0F-actin
HgeneAFAP1chr4:7787921chr4:20731752ENST00000382543-1117594_637510.0815.0F-actin
HgeneAFAP1chr4:7787921chr4:20731752ENST00000420658-1218594_637510.0815.0F-actin


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for AFAP1-KCNIP4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for AFAP1-KCNIP4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource