Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ELP4-CSTF3 (FusionGDB2 ID:26333)

Fusion Gene Summary for ELP4-CSTF3

Fusion gene summary

Fusion gene information	Fusion gene name: ELP4-CSTF3
	Fusion gene ID: 26333
		Hgene	Tgene
	Gene symbol	ELP4	CSTF3
	Gene ID	26610	1479
	Gene name	elongator acetyltransferase complex subunit 4	cleavage stimulation factor subunit 3
	Synonyms	AN\|AN2\|C11orf19\|PAX6NEB\|PAXNEB\|dJ68P15A.1\|hELP4	CSTF-77
	Cytomap	11p13	11p13
	Type of gene	protein-coding	protein-coding
	Description	elongator complex protein 4PAX6 neighbor gene proteinelongation protein 4 homolog	cleavage stimulation factor subunit 3CF-1 77 kDa subunitCSTF 77 kDa subunitcleavage stimulation factor 77 kDa subunitcleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDcleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
	Modification date	20200313	20200313
	UniProtAcc	Q96EB1	Q12996
	Ensembl transtripts involved in fusion gene	ENST00000350638, ENST00000379163, ENST00000395934,	ENST00000431742, ENST00000438862, ENST00000526480, ENST00000323959, ENST00000524827,
Fusion gene scores	* DoF score	15 X 12 X 7=1260	7 X 4 X 6=168
	# samples	14	8
	** MAII score	log2(14/1260*10)=-3.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/168*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ELP4 [Title/Abstract] AND CSTF3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ELP4(31671769)-CSTF3(33129964), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ELP4	GO:0006357	regulation of transcription by RNA polymerase II	11818576

Fusion gene breakpoints across ELP4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CSTF3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-FD-A3B8	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-

Top

Fusion Gene ORF analysis for ELP4-CSTF3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000350638	ENST00000431742	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000350638	ENST00000438862	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000350638	ENST00000526480	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000379163	ENST00000431742	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000379163	ENST00000438862	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000379163	ENST00000526480	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000395934	ENST00000431742	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000395934	ENST00000438862	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
5CDS-intron	ENST00000395934	ENST00000526480	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
In-frame	ENST00000350638	ENST00000323959	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
In-frame	ENST00000350638	ENST00000524827	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
In-frame	ENST00000379163	ENST00000323959	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
In-frame	ENST00000379163	ENST00000524827	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
In-frame	ENST00000395934	ENST00000323959	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-
In-frame	ENST00000395934	ENST00000524827	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000350638	ELP4	chr11	31671769	+	ENST00000323959	CSTF3	chr11	33129964	-	3610	1178	35	3106	1023
ENST00000350638	ELP4	chr11	31671769	+	ENST00000524827	CSTF3	chr11	33129964	-	1415	1178	35	1414	460
ENST00000379163	ELP4	chr11	31671769	+	ENST00000323959	CSTF3	chr11	33129964	-	3593	1161	15	3089	1024
ENST00000379163	ELP4	chr11	31671769	+	ENST00000524827	CSTF3	chr11	33129964	-	1398	1161	15	1397	460
ENST00000395934	ELP4	chr11	31671769	+	ENST00000323959	CSTF3	chr11	33129964	-	3582	1150	7	3078	1023
ENST00000395934	ELP4	chr11	31671769	+	ENST00000524827	CSTF3	chr11	33129964	-	1387	1150	7	1386	460

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000350638	ENST00000323959	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-	0.000292455	0.9997075
ENST00000350638	ENST00000524827	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-	0.000770566	0.99922943
ENST00000379163	ENST00000323959	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-	0.000334951	0.999665
ENST00000379163	ENST00000524827	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-	0.0007071	0.99929285
ENST00000395934	ENST00000323959	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-	0.000296182	0.9997038
ENST00000395934	ENST00000524827	ELP4	chr11	31671769	+	CSTF3	chr11	33129964	-	0.000812475	0.9991875

Top

Fusion Genomic Features for ELP4-CSTF3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ELP4-CSTF3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:31671769/chr11:33129964)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ELP4 Q96EB1	CSTF3 Q12996
FUNCTION: Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation (PubMed:11714725, PubMed:11818576, PubMed:16713582). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). {ECO:0000269\|PubMed:11714725, ECO:0000269\|PubMed:11818576, ECO:0000269\|PubMed:16713582, ECO:0000303\|PubMed:29332244}.	FUNCTION: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

559_626

718.0

Compositional bias

Note=Pro-rich

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

559_626

45.0

Compositional bias

Note=Pro-rich

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

559_626

104.0

Compositional bias

Note=Pro-rich

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

117_152

718.0

Repeat

Note=HAT 3

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

163_196

718.0

Repeat

Note=HAT 4

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

221_261

718.0

Repeat

Note=HAT 5

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

271_303

718.0

Repeat

Note=HAT 6

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

319_352

718.0

Repeat

Note=HAT 7

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

354_387

718.0

Repeat

Note=HAT 8

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

458_494

718.0

Repeat

Note=HAT 9

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

79_110

718.0

Repeat

Note=HAT 2

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

117_152

45.0

Repeat

Note=HAT 3

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

163_196

45.0

Repeat

Note=HAT 4

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

221_261

45.0

Repeat

Note=HAT 5

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

271_303

45.0

Repeat

Note=HAT 6

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

319_352

45.0

Repeat

Note=HAT 7

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

354_387

45.0

Repeat

Note=HAT 8

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

458_494

45.0

Repeat

Note=HAT 9

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

45_77

45.0

Repeat

Note=HAT 1

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000431742

79_110

45.0

Repeat

Note=HAT 2

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

117_152

104.0

Repeat

Note=HAT 3

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

163_196

104.0

Repeat

Note=HAT 4

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

221_261

104.0

Repeat

Note=HAT 5

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

271_303

104.0

Repeat

Note=HAT 6

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

319_352

104.0

Repeat

Note=HAT 7

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

354_387

104.0

Repeat

Note=HAT 8

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

458_494

104.0

Repeat

Note=HAT 9

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

45_77

104.0

Repeat

Note=HAT 1

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000438862

79_110

104.0

Repeat

Note=HAT 2

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

CSTF3

chr11:31671769

chr11:33129964

ENST00000323959

45_77

718.0

Repeat

Note=HAT 1

Top

Fusion Gene Sequence for ELP4-CSTF3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>26333_26333_1_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000350638_CSTF3_chr11_33129964_ENST00000323959_length(transcript)=3610nt_BP=1178nt
AGAGTTCCTATTGGGTTAACACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGG
CGACAGCCAGCAAGAGCAACGTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCA
TTGCGGGCACGCGACCGTCGGTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAG
CCGTTGGAACAGTTCTTCTAATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCA
ATGGGCATACTTTGTTGGTTGCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTA
AAAAGGAATTTGATGAAGATGTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCA
AGATGGAGATTGGACCAGTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAA
ATTGGCATGGATTTTTTCTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGTTCTTTGACCCCTGGCTACACAAAGCTGCTTC
AGTTTATCCAGAACATCATTTATGAGGAAGGATTTGATGGATCCAATCCTCAGAAAAAACAGAGAAACATTTTAAGAATAGGAATTCAGA
ATCTTGGCTCACCTTTATGGGGAGACGATATTTGCTGTGCAGAAAATGGTGGCAACAGTCACAGCCTTACCAAGTTCCTCTATGTTCTCC
GTGGTCTTCTGAGAACCTCTCTTTCAGCCTGCATCATCACAATGCCAACACATCTGATCCAGAATAAAGCCATTATTGCCCGTGTCACAA
CCTTGTCAGATGTAGTAGTTGGTCTGGAATCATTTATTGGTTCTGAGAGAGAAACTAACCCATTGTATAAGGATTATCATGGATTGATTC
ATATACGGCAGATTCCTCGGCTTAATAACTTGATCTGTGATGAATCAGATGTCAAAGACTTAGCTTTTAAATTAAAAAGGAAGCTATTCA
CCATTGAGATTAAAGCTAAAAATTATGACAAGGTTGAAAAGCTATTTCAGAGATGCCTTATGAAGGTTTTGCACATTGATTTATGGAAGT
GTTATCTTTCATATGTCCGAGAAACCAAGGGTAAACTACCAAGTTACAAAGAAAAAATGGCTCAAGCATATGACTTTGCACTGGATAAAA
TTGGAATGGAAATTATGTCCTATCAGATTTGGGTGGATTACATCAATTTCCTAAAAGGCGTGGAAGCTGTAGGATCTTATGCAGAAAATC
AAAGAATAACAGCTGTCCGAAGAGTTTATCAACGAGGTTGTGTTAATCCGATGATCAACATTGAACAGCTCTGGAGAGACTATAACAAGT
ATGAAGAGGGTATCAATATTCATTTAGCTAAAAAAATGATTGAAGATCGGAGTAGAGATTATATGAATGCTAGACGTGTAGCAAAGGAAT
ATGAGACAGTAATGAAAGGCTTGGACCGTAATGCTCCCTCGGTGCCTCCTCAGAATACTCCTCAAGAAGCTCAACAAGTAGATATGTGGA
AGAAATATATACAGTGGGAAAAGAGCAACCCTCTTCGTACAGAGGATCAGACCCTTATAACAAAAAGAGTTATGTTTGCTTATGAACAGT
GCCTGCTTGTGCTGGGCCATCACCCTGATATTTGGTATGAAGCTGCCCAGTATCTTGAGCAGTCAAGTAAACTGCTCGCAGAAAAGGGAG
ATATGAATAATGCCAAATTATTTAGTGATGAAGCTGCTAATATATATGAAAGAGCCATAAGCACTTTATTGAAGAAGAATATGCTTCTTT
ATTTTGCATATGCAGATTATGAAGAGAGTCGCATGAAGTATGAAAAGGTTCACAGTATATATAACAGACTTCTGGCAATTGAGGATATTG
ACCCTACCTTGGTATATATCCAATATATGAAATTTGCACGGAGAGCAGAAGGCATCAAATCTGGAAGAATGATATTTAAAAAAGCAAGAG
AAGATACCAGAACCCGCCACCATGTCTATGTTACTGCAGCACTCATGGAATATTACTGTAGTAAGGACAAATCTGTTGCCTTTAAGATTT
TTGAGCTGGGGCTAAAAAAATATGGAGACATTCCAGAGTATGTCCTGGCCTATATTGACTATCTTTCTCACCTCAATGAGGACAATAATA
CCCGAGTTTTGTTTGAACGAGTTTTAACATCTGGAAGCCTTCCTCCTGAGAAGTCTGGAGAAATCTGGGCCCGATTTCTAGCATTTGAAA
GTAATATTGGTGATCTAGCTAGTATACTCAAAGTGGAGAAAAGACGGTTTACAGCATTCAAAGAAGAGTATGAAGGGAAAGAAACGGCTT
TACTAGTAGATAGATACAAGTTCATGGATTTATATCCTTGCTCTGCAAGTGAATTAAAAGCACTTGGTTATAAGGATGTCTCCCGTGCTA
AGCTAGCAGCTATAATTCCGGACCCAGTTGTAGCTCCTTCTATAGTGCCTGTTCTGAAAGATGAAGTGGATAGAAAACCAGAATACCCTA
AACCAGACACTCAGCAGATGATTCCATTTCAGCCACGACATTTAGCACCTCCAGGTTTACACCCTGTACCTGGTGGAGTGTTCCCAGTCC
CTCCTGCAGCTGTTGTTTTAATGAAACTTCTCCCTCCTCCTATCTGTTTCCAGGGTCCTTTTGTACAAGTGGATGAACTGATGGAAATTT
TCCGAAGATGCAAGATACCAAATACTGTTGAGGAAGCTGTGAGGATCATTACTGGTGGGGCCCCAGAGCTAGCTGTAGAAGGCAACGGCC
CCGTGGAAAGTAATGCAGTACTCACCAAGGCCGTCAAAAGGCCCAACGAGGATTCAGATGAAGATGAAGAAAAGGGAGCCGTTGTCCCCC
CTGTTCATGACATTTACAGAGCACGGCAGCAGAAGCGGATTCGGTAGGGTTTTAAACGCCTCTGCAGAAAACTCCTGTCCAGGATTCCTT
TTGCCTCAAGTGGTATGTTTAAAAGAGACAACGCTTTGTTACAAGGTTCTTGGAAACAAAGTTGTATTGTCATTGGTGCCTCTATCACAT
GGTTCTTGAGAAAAAACAAACCAACCTGTGTGAATTTTAGAATACGGAACAGACCTATGCTCTAAGCAAAATTAGGTTTTCAAAAATGTG
AGAACAGTACAAAGTGGCAGAACCACATTTTGTTCCCTCTTCAAGGGTGTCTTGTATGTGCCGCTTGAAGATTTGTGAGTTTTTCAACAG
TTTTATTTTAAAAACTGGATGGCTTATGATTGTAAAGCATTTTATCACATTTTCTGAAAACAATTGTTCTTGGTTTGCTTATGTAGAGTC
CTGCCTTATTGTTTGTTTTTATTTATGGCAGAATGTATGAAATCCGTTTTGTAGTTTCAAATTTTAAAAGTCCTTTAAAAAATAAAAGGA

>26333_26333_1_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000350638_CSTF3_chr11_33129964_ENST00000323959_length(amino acids)=1023AA_BP=381
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDIC
CAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI
CDESDVKDLAFKLKRKLFTIEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWV
DYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNA
PSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSKLLAEKGDMNNAKLFSDEA
ANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTRHHVYVT
AALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKV
EKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQP
RHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVRIITGGAPELAVEGNGPVESNAVLTKAV

--------------------------------------------------------------
>26333_26333_2_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000350638_CSTF3_chr11_33129964_ENST00000524827_length(transcript)=1415nt_BP=1178nt
AGAGTTCCTATTGGGTTAACACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGG
CGACAGCCAGCAAGAGCAACGTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCA
TTGCGGGCACGCGACCGTCGGTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAG
CCGTTGGAACAGTTCTTCTAATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCA
ATGGGCATACTTTGTTGGTTGCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTA
AAAAGGAATTTGATGAAGATGTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCA
AGATGGAGATTGGACCAGTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAA
ATTGGCATGGATTTTTTCTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGTTCTTTGACCCCTGGCTACACAAAGCTGCTTC
AGTTTATCCAGAACATCATTTATGAGGAAGGATTTGATGGATCCAATCCTCAGAAAAAACAGAGAAACATTTTAAGAATAGGAATTCAGA
ATCTTGGCTCACCTTTATGGGGAGACGATATTTGCTGTGCAGAAAATGGTGGCAACAGTCACAGCCTTACCAAGTTCCTCTATGTTCTCC
GTGGTCTTCTGAGAACCTCTCTTTCAGCCTGCATCATCACAATGCCAACACATCTGATCCAGAATAAAGCCATTATTGCCCGTGTCACAA
CCTTGTCAGATGTAGTAGTTGGTCTGGAATCATTTATTGGTTCTGAGAGAGAAACTAACCCATTGTATAAGGATTATCATGGATTGATTC
ATATACGGCAGATTCCTCGGCTTAATAACTTGATCTGTGATGAATCAGATGTCAAAGACTTAGCTTTTAAATTAAAAAGGAAGCTATTCA
CCATTGAGATTAAAGCTAAAAATTATGACAAGGTTGAAAAGCTATTTCAGAGATGCCTTATGAAGGTTTTGCACATTGATTTATGGAAGT
GTTATCTTTCATATGTCCGAGAAACCAAGGGTAAACTACCAAGTTACAAAGAAAAAATGGCTCAAGCATATGACTTTGCACTGGATAAAA

>26333_26333_2_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000350638_CSTF3_chr11_33129964_ENST00000524827_length(amino acids)=460AA_BP=381
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDIC
CAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI
CDESDVKDLAFKLKRKLFTIEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWV

--------------------------------------------------------------
>26333_26333_3_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000379163_CSTF3_chr11_33129964_ENST00000323959_length(transcript)=3593nt_BP=1161nt
ACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAAC
GTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCG
GTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTA
ATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTT
GCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGAT
GTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGCAGATTGGACCA
GTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTT
CTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGTTCTTTGACCCCTGGCTACACAAAGCTGCTTCAGTTTATCCAGAACATC
ATTTATGAGGAAGGATTTGATGGATCCAATCCTCAGAAAAAACAGAGAAACATTTTAAGAATAGGAATTCAGAATCTTGGCTCACCTTTA
TGGGGAGACGATATTTGCTGTGCAGAAAATGGTGGCAACAGTCACAGCCTTACCAAGTTCCTCTATGTTCTCCGTGGTCTTCTGAGAACC
TCTCTTTCAGCCTGCATCATCACAATGCCAACACATCTGATCCAGAATAAAGCCATTATTGCCCGTGTCACAACCTTGTCAGATGTAGTA
GTTGGTCTGGAATCATTTATTGGTTCTGAGAGAGAAACTAACCCATTGTATAAGGATTATCATGGATTGATTCATATACGGCAGATTCCT
CGGCTTAATAACTTGATCTGTGATGAATCAGATGTCAAAGACTTAGCTTTTAAATTAAAAAGGAAGCTATTCACCATTGAGATTAAAGCT
AAAAATTATGACAAGGTTGAAAAGCTATTTCAGAGATGCCTTATGAAGGTTTTGCACATTGATTTATGGAAGTGTTATCTTTCATATGTC
CGAGAAACCAAGGGTAAACTACCAAGTTACAAAGAAAAAATGGCTCAAGCATATGACTTTGCACTGGATAAAATTGGAATGGAAATTATG
TCCTATCAGATTTGGGTGGATTACATCAATTTCCTAAAAGGCGTGGAAGCTGTAGGATCTTATGCAGAAAATCAAAGAATAACAGCTGTC
CGAAGAGTTTATCAACGAGGTTGTGTTAATCCGATGATCAACATTGAACAGCTCTGGAGAGACTATAACAAGTATGAAGAGGGTATCAAT
ATTCATTTAGCTAAAAAAATGATTGAAGATCGGAGTAGAGATTATATGAATGCTAGACGTGTAGCAAAGGAATATGAGACAGTAATGAAA
GGCTTGGACCGTAATGCTCCCTCGGTGCCTCCTCAGAATACTCCTCAAGAAGCTCAACAAGTAGATATGTGGAAGAAATATATACAGTGG
GAAAAGAGCAACCCTCTTCGTACAGAGGATCAGACCCTTATAACAAAAAGAGTTATGTTTGCTTATGAACAGTGCCTGCTTGTGCTGGGC
CATCACCCTGATATTTGGTATGAAGCTGCCCAGTATCTTGAGCAGTCAAGTAAACTGCTCGCAGAAAAGGGAGATATGAATAATGCCAAA
TTATTTAGTGATGAAGCTGCTAATATATATGAAAGAGCCATAAGCACTTTATTGAAGAAGAATATGCTTCTTTATTTTGCATATGCAGAT
TATGAAGAGAGTCGCATGAAGTATGAAAAGGTTCACAGTATATATAACAGACTTCTGGCAATTGAGGATATTGACCCTACCTTGGTATAT
ATCCAATATATGAAATTTGCACGGAGAGCAGAAGGCATCAAATCTGGAAGAATGATATTTAAAAAAGCAAGAGAAGATACCAGAACCCGC
CACCATGTCTATGTTACTGCAGCACTCATGGAATATTACTGTAGTAAGGACAAATCTGTTGCCTTTAAGATTTTTGAGCTGGGGCTAAAA
AAATATGGAGACATTCCAGAGTATGTCCTGGCCTATATTGACTATCTTTCTCACCTCAATGAGGACAATAATACCCGAGTTTTGTTTGAA
CGAGTTTTAACATCTGGAAGCCTTCCTCCTGAGAAGTCTGGAGAAATCTGGGCCCGATTTCTAGCATTTGAAAGTAATATTGGTGATCTA
GCTAGTATACTCAAAGTGGAGAAAAGACGGTTTACAGCATTCAAAGAAGAGTATGAAGGGAAAGAAACGGCTTTACTAGTAGATAGATAC
AAGTTCATGGATTTATATCCTTGCTCTGCAAGTGAATTAAAAGCACTTGGTTATAAGGATGTCTCCCGTGCTAAGCTAGCAGCTATAATT
CCGGACCCAGTTGTAGCTCCTTCTATAGTGCCTGTTCTGAAAGATGAAGTGGATAGAAAACCAGAATACCCTAAACCAGACACTCAGCAG
ATGATTCCATTTCAGCCACGACATTTAGCACCTCCAGGTTTACACCCTGTACCTGGTGGAGTGTTCCCAGTCCCTCCTGCAGCTGTTGTT
TTAATGAAACTTCTCCCTCCTCCTATCTGTTTCCAGGGTCCTTTTGTACAAGTGGATGAACTGATGGAAATTTTCCGAAGATGCAAGATA
CCAAATACTGTTGAGGAAGCTGTGAGGATCATTACTGGTGGGGCCCCAGAGCTAGCTGTAGAAGGCAACGGCCCCGTGGAAAGTAATGCA
GTACTCACCAAGGCCGTCAAAAGGCCCAACGAGGATTCAGATGAAGATGAAGAAAAGGGAGCCGTTGTCCCCCCTGTTCATGACATTTAC
AGAGCACGGCAGCAGAAGCGGATTCGGTAGGGTTTTAAACGCCTCTGCAGAAAACTCCTGTCCAGGATTCCTTTTGCCTCAAGTGGTATG
TTTAAAAGAGACAACGCTTTGTTACAAGGTTCTTGGAAACAAAGTTGTATTGTCATTGGTGCCTCTATCACATGGTTCTTGAGAAAAAAC
AAACCAACCTGTGTGAATTTTAGAATACGGAACAGACCTATGCTCTAAGCAAAATTAGGTTTTCAAAAATGTGAGAACAGTACAAAGTGG
CAGAACCACATTTTGTTCCCTCTTCAAGGGTGTCTTGTATGTGCCGCTTGAAGATTTGTGAGTTTTTCAACAGTTTTATTTTAAAAACTG
GATGGCTTATGATTGTAAAGCATTTTATCACATTTTCTGAAAACAATTGTTCTTGGTTTGCTTATGTAGAGTCCTGCCTTATTGTTTGTT

>26333_26333_3_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000379163_CSTF3_chr11_33129964_ENST00000323959_length(amino acids)=1024AA_BP=382
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSR
FGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDI
CCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNL
ICDESDVKDLAFKLKRKLFTIEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIW
VDYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRN
APSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSKLLAEKGDMNNAKLFSDE
AANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTRHHVYV
TAALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILK
VEKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQ
PRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVRIITGGAPELAVEGNGPVESNAVLTKA

--------------------------------------------------------------
>26333_26333_4_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000379163_CSTF3_chr11_33129964_ENST00000524827_length(transcript)=1398nt_BP=1161nt
ACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAAC
GTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCG
GTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTA
ATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTT
GCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGAT
GTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGCAGATTGGACCA
GTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTT
CTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGTTCTTTGACCCCTGGCTACACAAAGCTGCTTCAGTTTATCCAGAACATC
ATTTATGAGGAAGGATTTGATGGATCCAATCCTCAGAAAAAACAGAGAAACATTTTAAGAATAGGAATTCAGAATCTTGGCTCACCTTTA
TGGGGAGACGATATTTGCTGTGCAGAAAATGGTGGCAACAGTCACAGCCTTACCAAGTTCCTCTATGTTCTCCGTGGTCTTCTGAGAACC
TCTCTTTCAGCCTGCATCATCACAATGCCAACACATCTGATCCAGAATAAAGCCATTATTGCCCGTGTCACAACCTTGTCAGATGTAGTA
GTTGGTCTGGAATCATTTATTGGTTCTGAGAGAGAAACTAACCCATTGTATAAGGATTATCATGGATTGATTCATATACGGCAGATTCCT
CGGCTTAATAACTTGATCTGTGATGAATCAGATGTCAAAGACTTAGCTTTTAAATTAAAAAGGAAGCTATTCACCATTGAGATTAAAGCT
AAAAATTATGACAAGGTTGAAAAGCTATTTCAGAGATGCCTTATGAAGGTTTTGCACATTGATTTATGGAAGTGTTATCTTTCATATGTC
CGAGAAACCAAGGGTAAACTACCAAGTTACAAAGAAAAAATGGCTCAAGCATATGACTTTGCACTGGATAAAATTGGAATGGAAATTATG

>26333_26333_4_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000379163_CSTF3_chr11_33129964_ENST00000524827_length(amino acids)=460AA_BP=382
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSR
FGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDI
CCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNL
ICDESDVKDLAFKLKRKLFTIEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIW

--------------------------------------------------------------
>26333_26333_5_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000395934_CSTF3_chr11_33129964_ENST00000323959_length(transcript)=3582nt_BP=1150nt
CTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAACGTCACCAG
TTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCGGTGCGGAA
TGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTAATTGAGGA
GGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTTGCATCTGC
TAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGATGTATACAA
TCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGATTGGACCAGTATCATCTTC
AAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTTCTTCCAGAGAA
AATATCTTCAACTCTCAAAGTAGAACCCTGTTCTTTGACCCCTGGCTACACAAAGCTGCTTCAGTTTATCCAGAACATCATTTATGAGGA
AGGATTTGATGGATCCAATCCTCAGAAAAAACAGAGAAACATTTTAAGAATAGGAATTCAGAATCTTGGCTCACCTTTATGGGGAGACGA
TATTTGCTGTGCAGAAAATGGTGGCAACAGTCACAGCCTTACCAAGTTCCTCTATGTTCTCCGTGGTCTTCTGAGAACCTCTCTTTCAGC
CTGCATCATCACAATGCCAACACATCTGATCCAGAATAAAGCCATTATTGCCCGTGTCACAACCTTGTCAGATGTAGTAGTTGGTCTGGA
ATCATTTATTGGTTCTGAGAGAGAAACTAACCCATTGTATAAGGATTATCATGGATTGATTCATATACGGCAGATTCCTCGGCTTAATAA
CTTGATCTGTGATGAATCAGATGTCAAAGACTTAGCTTTTAAATTAAAAAGGAAGCTATTCACCATTGAGATTAAAGCTAAAAATTATGA
CAAGGTTGAAAAGCTATTTCAGAGATGCCTTATGAAGGTTTTGCACATTGATTTATGGAAGTGTTATCTTTCATATGTCCGAGAAACCAA
GGGTAAACTACCAAGTTACAAAGAAAAAATGGCTCAAGCATATGACTTTGCACTGGATAAAATTGGAATGGAAATTATGTCCTATCAGAT
TTGGGTGGATTACATCAATTTCCTAAAAGGCGTGGAAGCTGTAGGATCTTATGCAGAAAATCAAAGAATAACAGCTGTCCGAAGAGTTTA
TCAACGAGGTTGTGTTAATCCGATGATCAACATTGAACAGCTCTGGAGAGACTATAACAAGTATGAAGAGGGTATCAATATTCATTTAGC
TAAAAAAATGATTGAAGATCGGAGTAGAGATTATATGAATGCTAGACGTGTAGCAAAGGAATATGAGACAGTAATGAAAGGCTTGGACCG
TAATGCTCCCTCGGTGCCTCCTCAGAATACTCCTCAAGAAGCTCAACAAGTAGATATGTGGAAGAAATATATACAGTGGGAAAAGAGCAA
CCCTCTTCGTACAGAGGATCAGACCCTTATAACAAAAAGAGTTATGTTTGCTTATGAACAGTGCCTGCTTGTGCTGGGCCATCACCCTGA
TATTTGGTATGAAGCTGCCCAGTATCTTGAGCAGTCAAGTAAACTGCTCGCAGAAAAGGGAGATATGAATAATGCCAAATTATTTAGTGA
TGAAGCTGCTAATATATATGAAAGAGCCATAAGCACTTTATTGAAGAAGAATATGCTTCTTTATTTTGCATATGCAGATTATGAAGAGAG
TCGCATGAAGTATGAAAAGGTTCACAGTATATATAACAGACTTCTGGCAATTGAGGATATTGACCCTACCTTGGTATATATCCAATATAT
GAAATTTGCACGGAGAGCAGAAGGCATCAAATCTGGAAGAATGATATTTAAAAAAGCAAGAGAAGATACCAGAACCCGCCACCATGTCTA
TGTTACTGCAGCACTCATGGAATATTACTGTAGTAAGGACAAATCTGTTGCCTTTAAGATTTTTGAGCTGGGGCTAAAAAAATATGGAGA
CATTCCAGAGTATGTCCTGGCCTATATTGACTATCTTTCTCACCTCAATGAGGACAATAATACCCGAGTTTTGTTTGAACGAGTTTTAAC
ATCTGGAAGCCTTCCTCCTGAGAAGTCTGGAGAAATCTGGGCCCGATTTCTAGCATTTGAAAGTAATATTGGTGATCTAGCTAGTATACT
CAAAGTGGAGAAAAGACGGTTTACAGCATTCAAAGAAGAGTATGAAGGGAAAGAAACGGCTTTACTAGTAGATAGATACAAGTTCATGGA
TTTATATCCTTGCTCTGCAAGTGAATTAAAAGCACTTGGTTATAAGGATGTCTCCCGTGCTAAGCTAGCAGCTATAATTCCGGACCCAGT
TGTAGCTCCTTCTATAGTGCCTGTTCTGAAAGATGAAGTGGATAGAAAACCAGAATACCCTAAACCAGACACTCAGCAGATGATTCCATT
TCAGCCACGACATTTAGCACCTCCAGGTTTACACCCTGTACCTGGTGGAGTGTTCCCAGTCCCTCCTGCAGCTGTTGTTTTAATGAAACT
TCTCCCTCCTCCTATCTGTTTCCAGGGTCCTTTTGTACAAGTGGATGAACTGATGGAAATTTTCCGAAGATGCAAGATACCAAATACTGT
TGAGGAAGCTGTGAGGATCATTACTGGTGGGGCCCCAGAGCTAGCTGTAGAAGGCAACGGCCCCGTGGAAAGTAATGCAGTACTCACCAA
GGCCGTCAAAAGGCCCAACGAGGATTCAGATGAAGATGAAGAAAAGGGAGCCGTTGTCCCCCCTGTTCATGACATTTACAGAGCACGGCA
GCAGAAGCGGATTCGGTAGGGTTTTAAACGCCTCTGCAGAAAACTCCTGTCCAGGATTCCTTTTGCCTCAAGTGGTATGTTTAAAAGAGA
CAACGCTTTGTTACAAGGTTCTTGGAAACAAAGTTGTATTGTCATTGGTGCCTCTATCACATGGTTCTTGAGAAAAAACAAACCAACCTG
TGTGAATTTTAGAATACGGAACAGACCTATGCTCTAAGCAAAATTAGGTTTTCAAAAATGTGAGAACAGTACAAAGTGGCAGAACCACAT
TTTGTTCCCTCTTCAAGGGTGTCTTGTATGTGCCGCTTGAAGATTTGTGAGTTTTTCAACAGTTTTATTTTAAAAACTGGATGGCTTATG
ATTGTAAAGCATTTTATCACATTTTCTGAAAACAATTGTTCTTGGTTTGCTTATGTAGAGTCCTGCCTTATTGTTTGTTTTTATTTATGG

>26333_26333_5_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000395934_CSTF3_chr11_33129964_ENST00000323959_length(amino acids)=1023AA_BP=381
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDIC
CAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI
CDESDVKDLAFKLKRKLFTIEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWV
DYINFLKGVEAVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNA
PSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSKLLAEKGDMNNAKLFSDEA
ANIYERAISTLLKKNMLLYFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTRHHVYVT
AALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASILKV
EKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKPDTQQMIPFQP
RHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRRCKIPNTVEEAVRIITGGAPELAVEGNGPVESNAVLTKAV

--------------------------------------------------------------
>26333_26333_6_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000395934_CSTF3_chr11_33129964_ENST00000524827_length(transcript)=1387nt_BP=1150nt
CTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAACGTCACCAG
TTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCGGTGCGGAA
TGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTAATTGAGGA
GGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTTGCATCTGC
TAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGATGTATACAA
TCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGATTGGACCAGTATCATCTTC
AAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTTCTTCCAGAGAA
AATATCTTCAACTCTCAAAGTAGAACCCTGTTCTTTGACCCCTGGCTACACAAAGCTGCTTCAGTTTATCCAGAACATCATTTATGAGGA
AGGATTTGATGGATCCAATCCTCAGAAAAAACAGAGAAACATTTTAAGAATAGGAATTCAGAATCTTGGCTCACCTTTATGGGGAGACGA
TATTTGCTGTGCAGAAAATGGTGGCAACAGTCACAGCCTTACCAAGTTCCTCTATGTTCTCCGTGGTCTTCTGAGAACCTCTCTTTCAGC
CTGCATCATCACAATGCCAACACATCTGATCCAGAATAAAGCCATTATTGCCCGTGTCACAACCTTGTCAGATGTAGTAGTTGGTCTGGA
ATCATTTATTGGTTCTGAGAGAGAAACTAACCCATTGTATAAGGATTATCATGGATTGATTCATATACGGCAGATTCCTCGGCTTAATAA
CTTGATCTGTGATGAATCAGATGTCAAAGACTTAGCTTTTAAATTAAAAAGGAAGCTATTCACCATTGAGATTAAAGCTAAAAATTATGA
CAAGGTTGAAAAGCTATTTCAGAGATGCCTTATGAAGGTTTTGCACATTGATTTATGGAAGTGTTATCTTTCATATGTCCGAGAAACCAA
GGGTAAACTACCAAGTTACAAAGAAAAAATGGCTCAAGCATATGACTTTGCACTGGATAAAATTGGAATGGAAATTATGTCCTATCAGAT

>26333_26333_6_ELP4-CSTF3_ELP4_chr11_31671769_ENST00000395934_CSTF3_chr11_33129964_ENST00000524827_length(amino acids)=460AA_BP=381
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDIC
CAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLI
CDESDVKDLAFKLKRKLFTIEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ELP4-CSTF3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ELP4-CSTF3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ELP4-CSTF3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source