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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ELP4-FREM1 (FusionGDB2 ID:26337)

Fusion Gene Summary for ELP4-FREM1

check button Fusion gene summary
Fusion gene informationFusion gene name: ELP4-FREM1
Fusion gene ID: 26337
HgeneTgene
Gene symbol

ELP4

FREM1

Gene ID

26610

158326

Gene nameelongator acetyltransferase complex subunit 4FRAS1 related extracellular matrix 1
SynonymsAN|AN2|C11orf19|PAX6NEB|PAXNEB|dJ68P15A.1|hELP4BNAR|C9orf143|C9orf145|C9orf154|MOTA|TILRR|TRIGNO2
Cytomap

11p13

9p22.3

Type of geneprotein-codingprotein-coding
Descriptionelongator complex protein 4PAX6 neighbor gene proteinelongation protein 4 homologFRAS1-related extracellular matrix protein 1extracellular matrix protein QBRICK
Modification date2020031320200321
UniProtAcc

Q96EB1

Q5H8C1

Ensembl transtripts involved in fusion geneENST00000350638, ENST00000379163, 
ENST00000395934, 		ENST00000380894, 
ENST00000486223, ENST00000380880, 
ENST00000380881, ENST00000422223, 
Fusion gene scores* DoF score15 X 12 X 7=12604 X 5 X 4=80
# samples 144
** MAII scorelog2(14/1260*10)=-3.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/80*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ELP4 [Title/Abstract] AND FREM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointELP4(31625454)-FREM1(14816869), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneELP4

GO:0006357

regulation of transcription by RNA polymerase II

11818576


check buttonFusion gene breakpoints across ELP4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FREM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CHOLTCGA-ZU-A8S4-01AELP4chr11

31625454

-FREM1chr9

14816869

-


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Fusion Gene ORF analysis for ELP4-FREM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000350638ENST00000380894ELP4chr11

31625454

-FREM1chr9

14816869

-
5CDS-intronENST00000350638ENST00000486223ELP4chr11

31625454

-FREM1chr9

14816869

-
5CDS-intronENST00000379163ENST00000380894ELP4chr11

31625454

-FREM1chr9

14816869

-
5CDS-intronENST00000379163ENST00000486223ELP4chr11

31625454

-FREM1chr9

14816869

-
5CDS-intronENST00000395934ENST00000380894ELP4chr11

31625454

-FREM1chr9

14816869

-
5CDS-intronENST00000395934ENST00000486223ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000350638ENST00000380880ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000350638ENST00000380881ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000350638ENST00000422223ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000379163ENST00000380880ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000379163ENST00000380881ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000379163ENST00000422223ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000395934ENST00000380880ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000395934ENST00000380881ELP4chr11

31625454

-FREM1chr9

14816869

-
In-frameENST00000395934ENST00000422223ELP4chr11

31625454

-FREM1chr9

14816869

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000350638ELP4chr1131625454-ENST00000422223FREM1chr914816869-74126883546811548
ENST00000350638ELP4chr1131625454-ENST00000380881FREM1chr914816869-74126883546811548
ENST00000350638ELP4chr1131625454-ENST00000380880FREM1chr914816869-46826883546811549
ENST00000379163ELP4chr1131625454-ENST00000422223FREM1chr914816869-73956711546641549
ENST00000379163ELP4chr1131625454-ENST00000380881FREM1chr914816869-73956711546641549
ENST00000379163ELP4chr1131625454-ENST00000380880FREM1chr914816869-46656711546641549
ENST00000395934ELP4chr1131625454-ENST00000422223FREM1chr914816869-7384660746531548
ENST00000395934ELP4chr1131625454-ENST00000380881FREM1chr914816869-7384660746531548
ENST00000395934ELP4chr1131625454-ENST00000380880FREM1chr914816869-4654660746531549

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000350638ENST00000422223ELP4chr1131625454-FREM1chr914816869-0.0001184340.9998815
ENST00000350638ENST00000380881ELP4chr1131625454-FREM1chr914816869-0.0001184340.9998815
ENST00000350638ENST00000380880ELP4chr1131625454-FREM1chr914816869-0.0004967490.99950325
ENST00000379163ENST00000422223ELP4chr1131625454-FREM1chr914816869-0.0001216380.9998784
ENST00000379163ENST00000380881ELP4chr1131625454-FREM1chr914816869-0.0001216380.9998784
ENST00000379163ENST00000380880ELP4chr1131625454-FREM1chr914816869-0.0005281580.99947184
ENST00000395934ENST00000422223ELP4chr1131625454-FREM1chr914816869-0.000116620.9998834
ENST00000395934ENST00000380881ELP4chr1131625454-FREM1chr914816869-0.000116620.9998834
ENST00000395934ENST00000380880ELP4chr1131625454-FREM1chr914816869-0.0004980260.99950194

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Fusion Genomic Features for ELP4-FREM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ELP4-FREM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:31625454/chr9:14816869)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ELP4

Q96EB1

FREM1

Q5H8C1

FUNCTION: Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation (PubMed:11714725, PubMed:11818576, PubMed:16713582). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). {ECO:0000269|PubMed:11714725, ECO:0000269|PubMed:11818576, ECO:0000269|PubMed:16713582, ECO:0000303|PubMed:29332244}.FUNCTION: Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371731_18308482180.0DomainNote=Calx-beta
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013372060_21748482180.0DomainC-type lectin
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141731_18300716.0DomainNote=Calx-beta
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940142060_21740716.0DomainC-type lectin
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381731_18308482180.0DomainNote=Calx-beta
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314382060_21748482180.0DomainC-type lectin
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371907_19098482180.0MotifCell attachment site
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141907_19090716.0MotifCell attachment site
TgeneFREM1chr11:31625454chr9:14816869ENST00000380894014199_2010716.0MotifCell attachment site
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381907_19098482180.0MotifCell attachment site
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371024_11268482180.0RepeatCSPG 7
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371147_12548482180.0RepeatCSPG 8
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371275_13728482180.0RepeatCSPG 9
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371393_14858482180.0RepeatCSPG 10
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371506_15968482180.0RepeatCSPG 11
TgeneFREM1chr11:31625454chr9:14816869ENST0000038088013371628_17248482180.0RepeatCSPG 12
TgeneFREM1chr11:31625454chr9:14816869ENST000003808801337887_9828482180.0RepeatCSPG 6
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141024_11260716.0RepeatCSPG 7
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141147_12540716.0RepeatCSPG 8
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141275_13720716.0RepeatCSPG 9
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141393_14850716.0RepeatCSPG 10
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141506_15960716.0RepeatCSPG 11
TgeneFREM1chr11:31625454chr9:14816869ENST000003808940141628_17240716.0RepeatCSPG 12
TgeneFREM1chr11:31625454chr9:14816869ENST00000380894014296_3900716.0RepeatCSPG 1
TgeneFREM1chr11:31625454chr9:14816869ENST00000380894014413_5000716.0RepeatCSPG 2
TgeneFREM1chr11:31625454chr9:14816869ENST00000380894014521_6150716.0RepeatCSPG 3
TgeneFREM1chr11:31625454chr9:14816869ENST00000380894014642_7540716.0RepeatCSPG 4
TgeneFREM1chr11:31625454chr9:14816869ENST00000380894014776_8670716.0RepeatCSPG 5
TgeneFREM1chr11:31625454chr9:14816869ENST00000380894014887_9820716.0RepeatCSPG 6
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381024_11268482180.0RepeatCSPG 7
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381147_12548482180.0RepeatCSPG 8
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381275_13728482180.0RepeatCSPG 9
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381393_14858482180.0RepeatCSPG 10
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381506_15968482180.0RepeatCSPG 11
TgeneFREM1chr11:31625454chr9:14816869ENST0000042222314381628_17248482180.0RepeatCSPG 12
TgeneFREM1chr11:31625454chr9:14816869ENST000004222231438887_9828482180.0RepeatCSPG 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFREM1chr11:31625454chr9:14816869ENST000003808801337199_2018482180.0MotifCell attachment site
TgeneFREM1chr11:31625454chr9:14816869ENST000004222231438199_2018482180.0MotifCell attachment site
TgeneFREM1chr11:31625454chr9:14816869ENST000003808801337296_3908482180.0RepeatCSPG 1
TgeneFREM1chr11:31625454chr9:14816869ENST000003808801337413_5008482180.0RepeatCSPG 2
TgeneFREM1chr11:31625454chr9:14816869ENST000003808801337521_6158482180.0RepeatCSPG 3
TgeneFREM1chr11:31625454chr9:14816869ENST000003808801337642_7548482180.0RepeatCSPG 4
TgeneFREM1chr11:31625454chr9:14816869ENST000003808801337776_8678482180.0RepeatCSPG 5
TgeneFREM1chr11:31625454chr9:14816869ENST000004222231438296_3908482180.0RepeatCSPG 1
TgeneFREM1chr11:31625454chr9:14816869ENST000004222231438413_5008482180.0RepeatCSPG 2
TgeneFREM1chr11:31625454chr9:14816869ENST000004222231438521_6158482180.0RepeatCSPG 3
TgeneFREM1chr11:31625454chr9:14816869ENST000004222231438642_7548482180.0RepeatCSPG 4
TgeneFREM1chr11:31625454chr9:14816869ENST000004222231438776_8678482180.0RepeatCSPG 5


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Fusion Gene Sequence for ELP4-FREM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26337_26337_1_ELP4-FREM1_ELP4_chr11_31625454_ENST00000350638_FREM1_chr9_14816869_ENST00000380880_length(transcript)=4682nt_BP=688nt
AGAGTTCCTATTGGGTTAACACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGG
CGACAGCCAGCAAGAGCAACGTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCA
TTGCGGGCACGCGACCGTCGGTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAG
CCGTTGGAACAGTTCTTCTAATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCA
ATGGGCATACTTTGTTGGTTGCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTA
AAAAGGAATTTGATGAAGATGTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCA
AGATGGAGATTGGACCAGTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAA
ATTGGCATGGATTTTTTCTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGG
ATGACCTACTCTTGGAGGTCACCGATGGCACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAG
TCTTAAAGGCTGACCTCATGCCTGTCATGAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGG
ACAGCGATAACTTGAAGTTGATGTTTGTGATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCT
CTCAGAGAGATGTTATCTCAGAGGCCGTGACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGG
TGGTTTCGGATGGAGAGGCTGGCCCTTTTGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAG
TGTATGATCTCAACATCACGGTATACCCAGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCT
CAACAGCCCTTACTGTTAACCATTTGTCCGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGT
TTGGCTACCTCGAAAATATACTCCCTTCTGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGA
ACGCTTTTCACATTAACTATGTGCAGTCCAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGC
ATCACTCCTTGGAGATACCATTTTCTATTATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTG
AGGGTCAGATGAAAGAGCTGGACTCTTCCATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAA
AGCCACGCCATGGCCTCCTCATCGATAGGGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCAC
CTGTTCACAGCTTTTCCATGGAACTCCTCAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTA
CAATCCAATTGTCAGATGGGAAACATAAGATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCA
AGAAGGCTGAAATTGCAATGAATATGGGTGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGA
AGATTTACTATGTATTTGAAAGGCTTCCCCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGA
AATGCACTCAGGAGGAAGTGGATCTGAACTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCT
ACCTTTGGGATGGCAACAACAGGTCCCCTGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAA
AACCACTCGTGGTGTCTAAAGGTGATAGAGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGC
TCTATGTCATCACCTCCCCTCCGCGATATGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATG
TAGTGGGGCAGACAGTTTGCTATGTACACAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGA
CCGAGCACGGGGTGTTTGAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAG
GGGCCGTGGGCCTGCTTTCCCCTGACCTCCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCC
CCCAGCATGGCCAGCTCTACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATC
GGCACTCAGGAGGGGACTCCCAGACTGACTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGT
GGGAAGAACCTGTTTTATTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGG
GGCTCCTGAAAAATGGCTGCTACGGGATTTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCT
TTAAAATTCTACAAGGCCCAAAACATGGACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAA
ACAGTAAGACTATTCTTTACATCATAAACCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACT
CGGCCACTCCTCAAATTTTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGC
CCTTGGAAATTATCAGAAGGGGATATTCCATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATT
TCACCGTGATTCCATCTAAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGG
AAGATGATGAGGTCTTTGAAGTAATTCTGAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACT
CAAAAGGAGGACAATGCCATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAG
GGTCTTCCTCATCCACCACTTCTGGTTCCTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACA
CCCTGCGGGGCTTTGATTCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATA
GAAATGGAACAGACATCATCTATAATTATCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCA
AAGTATCCATCATTAGTCAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACT
TCCCCAGACAGGACCAGTTGCCCTCATTTCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGC
TGTATCAGTGCAATGGGATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGC
ACTCAGGCTACTGTCACATCTTGATCACAGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACC
TTGTAACTGTATTCTCCAGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGC
ATGCTGGCCACTGGGAGTGGATCGGTGGTGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGA
GCTGTGTTTTGGTTCAAAGACAAGGGAAATGGCAAACAAAAGACTGTAGGAGAGCCAAACCTCATAATTATGTGTGTTCCAGAAAACTCT

>26337_26337_1_ELP4-FREM1_ELP4_chr11_31625454_ENST00000350638_FREM1_chr9_14816869_ENST00000380880_length(amino acids)=1549AA_BP=218
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNC
SEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVN
GCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVG
FEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSII
SAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKIL
KTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLL
RYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQ
IEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQ
LTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVD
QLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPS
LEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFD
PGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFH
LERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTI
KVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQ
KGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQ

--------------------------------------------------------------
>26337_26337_2_ELP4-FREM1_ELP4_chr11_31625454_ENST00000350638_FREM1_chr9_14816869_ENST00000380881_length(transcript)=7412nt_BP=688nt
AGAGTTCCTATTGGGTTAACACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGG
CGACAGCCAGCAAGAGCAACGTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCA
TTGCGGGCACGCGACCGTCGGTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAG
CCGTTGGAACAGTTCTTCTAATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCA
ATGGGCATACTTTGTTGGTTGCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTA
AAAAGGAATTTGATGAAGATGTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCA
AGATGGAGATTGGACCAGTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAA
ATTGGCATGGATTTTTTCTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGG
ATGACCTACTCTTGGAGGTCACCGATGGCACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAG
TCTTAAAGGCTGACCTCATGCCTGTCATGAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGG
ACAGCGATAACTTGAAGTTGATGTTTGTGATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCT
CTCAGAGAGATGTTATCTCAGAGGCCGTGACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGG
TGGTTTCGGATGGAGAGGCTGGCCCTTTTGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAG
TGTATGATCTCAACATCACGGTATACCCAGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCT
CAACAGCCCTTACTGTTAACCATTTGTCCGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGT
TTGGCTACCTCGAAAATATACTCCCTTCTGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGA
ACGCTTTTCACATTAACTATGTGCAGTCCAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGC
ATCACTCCTTGGAGATACCATTTTCTATTATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTG
AGGGTCAGATGAAAGAGCTGGACTCTTCCATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAA
AGCCACGCCATGGCCTCCTCATCGATAGGGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCAC
CTGTTCACAGCTTTTCCATGGAACTCCTCAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTA
CAATCCAATTGTCAGATGGGAAACATAAGATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCA
AGAAGGCTGAAATTGCAATGAATATGGGTGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGA
AGATTTACTATGTATTTGAAAGGCTTCCCCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGA
AATGCACTCAGGAGGAAGTGGATCTGAACTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCT
ACCTTTGGGATGGCAACAACAGGTCCCCTGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAA
AACCACTCGTGGTGTCTAAAGGTGATAGAGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGC
TCTATGTCATCACCTCCCCTCCGCGATATGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATG
TAGTGGGGCAGACAGTTTGCTATGTACACAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGA
CCGAGCACGGGGTGTTTGAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAG
GGGCCGTGGGCCTGCTTTCCCCTGACCTCCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCC
CCCAGCATGGCCAGCTCTACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATC
GGCACTCAGGAGGGGACTCCCAGACTGACTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGT
GGGAAGAACCTGTTTTATTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGG
GGCTCCTGAAAAATGGCTGCTACGGGATTTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCT
TTAAAATTCTACAAGGCCCAAAACATGGACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAA
ACAGTAAGACTATTCTTTACATCATAAACCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACT
CGGCCACTCCTCAAATTTTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGC
CCTTGGAAATTATCAGAAGGGGATATTCCATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATT
TCACCGTGATTCCATCTAAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGG
AAGATGATGAGGTCTTTGAAGTAATTCTGAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACT
CAAAAGGAGGACAATGCCATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAG
GGTCTTCCTCATCCACCACTTCTGGTTCCTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACA
CCCTGCGGGGCTTTGATTCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATA
GAAATGGAACAGACATCATCTATAATTATCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCA
AAGTATCCATCATTAGTCAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACT
TCCCCAGACAGGACCAGTTGCCCTCATTTCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGC
TGTATCAGTGCAATGGGATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGC
ACTCAGGCTACTGTCACATCTTGATCACAGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACC
TTGTAACTGTATTCTCCAGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGC
ATGCTGGCCACTGGGAGTGGATCGGTGGTGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGA
GCTGTGTTTTGGTTCAAAGACAAGGGAAATGGCAAACAAAAGACTGTAGGAGAGCCAAACCTCATAATTATGTGTGTTCCAGAAAACTCT
AAATATAACAGACCCTACAGGGGGCCACCTGGAGTTTGTCACCTATTTATTCACAGGATCTGTGAATATTGCTCCATAGAAAACAAATTG
TTATGATTGAGTGGGTATACCTTTGTGATTCTGTCTAGTGAAAATGGGACATTTTTAATAGTGCCAGAAAGATTGATAAATAAATATTTT
TTACAAGATAAGATACAATTTTTGTATCTCAATACCTTTTAAAATAAATGCCAGCAGTATTATAAAGTGTAAGGTTTGTTTATTCCAGAA
GACCCTCACCCTTACCCCATTCCAAATCTCAGGGAGCACCAGTCTCATAGTCCTTGGATTTTTTTAAAAAAAATTTTTGGTCCCGTTACC
TCTAATGAATTTATTCTGAAATATGTATCGTAGGTGCTCCTACCACTTTAGTCTGAGTGAAGCTAACTCTACTAGTTCATTAAACCAAAG
TTGAACCGCAAAGTTGTCCCTTTGGAGCCCTTTAAATGTGAAATCTAAGATTAGAGGCTGGGGTTGAAAAAGAGAATTTTCTATGATGAA
AAAGAAAGACTTTAGATGAAAGAATCTTGTAGGTGGAGGCTCATCTACAAAGCTGTAGTTCAGGTAAGAATTCGGGGGGCTGGCTGTACT
CAGAGTTCTACTCATCACTATTCATGAAACAGATCTCCCTTTCCAATTTGAGTGTTGGCATTGTACCATCCCAAAGCTAATGATTGGGTT
TCCCCAGCCTTACAGAGTCATGAGAAATTTCAAGTAACATAATCTGTTCCTCTGTGTTTATTGTACTGACAAGCATTTCTCAGGGACACT
TGGGATAAGGAGTATATATGAATGATGGTTGACACATGGAAGAAAAATACTGCTTCCTCAGAAATGTCCTGATGAACTGTGCTGATGAAC
AGAGAAAAATAATACCGAAAACAGAGCCCCTGAAAGCCTACATTCTCGGAAAGGATTTTGAGGAATTTTGAGCCACCTTAAATCTTTAAT
ATTTGCAGAAATGCCATGTTAACTAGATTCTCTAACGGAAAGGTACCTTATTAATTTATAATCTCAGGTGAGTGGAACATTTTTGTAACA
ATGAAGTATGTTGCAGCGTTACCAGAACTCCCTTCTGAAATCAAGGTTTAACAGTTATAGGAAATTAGAATGTCTGAAACATTTATTTAA
AGTTTTTCTCTTTTCATAATCACTGAGAAATATGGTTGTGCCAAATGTCACTTGCTCTATGAGCACCAATGTAACTTCAGAATCAAATTG
GGGTTATCAAGTAGGCTAGAGCTCTGGTGCTGGTTTTATTATAAAAATACCTTGAGTGTTGTAGACACTAAAACTGCTTGAAGAAAGTCA
GTTCAGTTTCTGGGATATAAAAACATGGCAAGCTTTTTTTATTTCAGTTCATTTATCAAGGTTGTAATTAATAGAAACATTTAGAAAGAG
ATATTGGAATATGATCCAGACATTCTGTCTATTACTTAAATCTAAACATAATTATAGTGTCAGAGGGTCCTTACCTGAGATGTCGCAGGT
GGGCTCCAGATTGGCATAATGTACAGGTTCTCTGTGAGACACAAGCAGTTTCTGGCATTTAACCAAAAGATGCCACACCTATCCTCTTAC
CAGCTCCTTTCAAATTCCTTCTGGTCCACAGGCTTCTTGCAGTATGGAAATGTGAGATTTGGGCTAAAGAAAAAATAGTTGTTTACCTAA
AGGGTTAAGTCCTAGGAAGGAAGTAGAAGTTTGGGAAATGAGGGATTCAAGGGCCACTCCTTCCACTGGAACTCTAAAACTATATAAACC
ATCTAAAACTGGAAATCTAGAACTATGTCAACTGTGTAGAACCTTGTCAGCATGGCAGATTTATTATACATTTCTGCAATATAAATGATA
AATGATACTGAACTAATTGCAAATGTTAGCATAAAGAGTGTTTTGATTTTTATAACAATTAGAAATGCTACAAGAATATTTAAAAATATT
CCTGATCATGAAAGCATTAATCAAATTAGAAAATCCAAGTCATTTTAAGAAGATAAAAATAGAAATTCAGGCAAGTTTGGGTGATGGGCG
GTATTCATCACAACCTTCATTTTATTCTTACAATTGAGCTTTGACTCAGGGGGAAAAGAAGTAAATGATTGTCAAGGTTCCCTCTGCCTT
GATTGATAGTTTCTGATGGGAGTGGGAAGGAAGGAATTGGAGTAATGGGTAGAATGGGAATGAGAGATTACGGGAGAGAGAGATGAGATG
GGTTGAACAGAAGAGGATGGGAACTGATGGTAGCTAGGAAGGAAAGCGTCAAGAAGGACCTGAATGTACCCAGCTTTTCTCCCCAAACTT
CAATACCACCTCAGGAAAAGGCCCACTGTGTCCAGGGGCGTCAGTCCAGCTCAATAGTGTCTAGCTTTTCAGAATCTTCTGATTGTTTGG
TCTTTAACAAAAACATAGCATCTATTTGCTAACAATAAACTTAAGCAACATATGATAATCATTTCATCTCCTTCCAAGAAGTGGTGAAAA
TGAACCAGGTGACATTAATTTAACTTCTGTTTTTGTTTATTTTTAATACAACCAAAAAGATATGCACATATTTTAATTTACATTATGGTA
CTGTATAATTTAAACCATAAACTGGTGCTGATTAATTTCTGCAACAAAGCAGCATATTAAATGTACTACATCTAGTGTTGTAGCAAAATT

>26337_26337_2_ELP4-FREM1_ELP4_chr11_31625454_ENST00000350638_FREM1_chr9_14816869_ENST00000380881_length(amino acids)=1548AA_BP=218
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNC
SEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVN
GCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVG
FEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSII
SAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKIL
KTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLL
RYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQ
IEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQ
LTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVD
QLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPS
LEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFD
PGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFH
LERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTI
KVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQ
KGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQ

--------------------------------------------------------------
>26337_26337_3_ELP4-FREM1_ELP4_chr11_31625454_ENST00000350638_FREM1_chr9_14816869_ENST00000422223_length(transcript)=7412nt_BP=688nt
AGAGTTCCTATTGGGTTAACACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGG
CGACAGCCAGCAAGAGCAACGTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCA
TTGCGGGCACGCGACCGTCGGTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAG
CCGTTGGAACAGTTCTTCTAATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCA
ATGGGCATACTTTGTTGGTTGCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTA
AAAAGGAATTTGATGAAGATGTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCA
AGATGGAGATTGGACCAGTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAA
ATTGGCATGGATTTTTTCTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGG
ATGACCTACTCTTGGAGGTCACCGATGGCACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAG
TCTTAAAGGCTGACCTCATGCCTGTCATGAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGG
ACAGCGATAACTTGAAGTTGATGTTTGTGATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCT
CTCAGAGAGATGTTATCTCAGAGGCCGTGACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGG
TGGTTTCGGATGGAGAGGCTGGCCCTTTTGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAG
TGTATGATCTCAACATCACGGTATACCCAGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCT
CAACAGCCCTTACTGTTAACCATTTGTCCGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGT
TTGGCTACCTCGAAAATATACTCCCTTCTGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGA
ACGCTTTTCACATTAACTATGTGCAGTCCAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGC
ATCACTCCTTGGAGATACCATTTTCTATTATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTG
AGGGTCAGATGAAAGAGCTGGACTCTTCCATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAA
AGCCACGCCATGGCCTCCTCATCGATAGGGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCAC
CTGTTCACAGCTTTTCCATGGAACTCCTCAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTA
CAATCCAATTGTCAGATGGGAAACATAAGATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCA
AGAAGGCTGAAATTGCAATGAATATGGGTGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGA
AGATTTACTATGTATTTGAAAGGCTTCCCCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGA
AATGCACTCAGGAGGAAGTGGATCTGAACTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCT
ACCTTTGGGATGGCAACAACAGGTCCCCTGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAA
AACCACTCGTGGTGTCTAAAGGTGATAGAGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGC
TCTATGTCATCACCTCCCCTCCGCGATATGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATG
TAGTGGGGCAGACAGTTTGCTATGTACACAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGA
CCGAGCACGGGGTGTTTGAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAG
GGGCCGTGGGCCTGCTTTCCCCTGACCTCCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCC
CCCAGCATGGCCAGCTCTACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATC
GGCACTCAGGAGGGGACTCCCAGACTGACTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGT
GGGAAGAACCTGTTTTATTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGG
GGCTCCTGAAAAATGGCTGCTACGGGATTTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCT
TTAAAATTCTACAAGGCCCAAAACATGGACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAA
ACAGTAAGACTATTCTTTACATCATAAACCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACT
CGGCCACTCCTCAAATTTTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGC
CCTTGGAAATTATCAGAAGGGGATATTCCATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATT
TCACCGTGATTCCATCTAAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGG
AAGATGATGAGGTCTTTGAAGTAATTCTGAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACT
CAAAAGGAGGACAATGCCATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAG
GGTCTTCCTCATCCACCACTTCTGGTTCCTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACA
CCCTGCGGGGCTTTGATTCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATA
GAAATGGAACAGACATCATCTATAATTATCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCA
AAGTATCCATCATTAGTCAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACT
TCCCCAGACAGGACCAGTTGCCCTCATTTCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGC
TGTATCAGTGCAATGGGATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGC
ACTCAGGCTACTGTCACATCTTGATCACAGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACC
TTGTAACTGTATTCTCCAGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGC
ATGCTGGCCACTGGGAGTGGATCGGTGGTGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGA
GCTGTGTTTTGGTTCAAAGACAAGGGAAATGGCAAACAAAAGACTGTAGGAGAGCCAAACCTCATAATTATGTGTGTTCCAGAAAACTCT
AAATATAACAGACCCTACAGGGGGCCACCTGGAGTTTGTCACCTATTTATTCACAGGATCTGTGAATATTGCTCCATAGAAAACAAATTG
TTATGATTGAGTGGGTATACCTTTGTGATTCTGTCTAGTGAAAATGGGACATTTTTAATAGTGCCAGAAAGATTGATAAATAAATATTTT
TTACAAGATAAGATACAATTTTTGTATCTCAATACCTTTTAAAATAAATGCCAGCAGTATTATAAAGTGTAAGGTTTGTTTATTCCAGAA
GACCCTCACCCTTACCCCATTCCAAATCTCAGGGAGCACCAGTCTCATAGTCCTTGGATTTTTTTAAAAAAAATTTTTGGTCCCGTTACC
TCTAATGAATTTATTCTGAAATATGTATCGTAGGTGCTCCTACCACTTTAGTCTGAGTGAAGCTAACTCTACTAGTTCATTAAACCAAAG
TTGAACCGCAAAGTTGTCCCTTTGGAGCCCTTTAAATGTGAAATCTAAGATTAGAGGCTGGGGTTGAAAAAGAGAATTTTCTATGATGAA
AAAGAAAGACTTTAGATGAAAGAATCTTGTAGGTGGAGGCTCATCTACAAAGCTGTAGTTCAGGTAAGAATTCGGGGGGCTGGCTGTACT
CAGAGTTCTACTCATCACTATTCATGAAACAGATCTCCCTTTCCAATTTGAGTGTTGGCATTGTACCATCCCAAAGCTAATGATTGGGTT
TCCCCAGCCTTACAGAGTCATGAGAAATTTCAAGTAACATAATCTGTTCCTCTGTGTTTATTGTACTGACAAGCATTTCTCAGGGACACT
TGGGATAAGGAGTATATATGAATGATGGTTGACACATGGAAGAAAAATACTGCTTCCTCAGAAATGTCCTGATGAACTGTGCTGATGAAC
AGAGAAAAATAATACCGAAAACAGAGCCCCTGAAAGCCTACATTCTCGGAAAGGATTTTGAGGAATTTTGAGCCACCTTAAATCTTTAAT
ATTTGCAGAAATGCCATGTTAACTAGATTCTCTAACGGAAAGGTACCTTATTAATTTATAATCTCAGGTGAGTGGAACATTTTTGTAACA
ATGAAGTATGTTGCAGCGTTACCAGAACTCCCTTCTGAAATCAAGGTTTAACAGTTATAGGAAATTAGAATGTCTGAAACATTTATTTAA
AGTTTTTCTCTTTTCATAATCACTGAGAAATATGGTTGTGCCAAATGTCACTTGCTCTATGAGCACCAATGTAACTTCAGAATCAAATTG
GGGTTATCAAGTAGGCTAGAGCTCTGGTGCTGGTTTTATTATAAAAATACCTTGAGTGTTGTAGACACTAAAACTGCTTGAAGAAAGTCA
GTTCAGTTTCTGGGATATAAAAACATGGCAAGCTTTTTTTATTTCAGTTCATTTATCAAGGTTGTAATTAATAGAAACATTTAGAAAGAG
ATATTGGAATATGATCCAGACATTCTGTCTATTACTTAAATCTAAACATAATTATAGTGTCAGAGGGTCCTTACCTGAGATGTCGCAGGT
GGGCTCCAGATTGGCATAATGTACAGGTTCTCTGTGAGACACAAGCAGTTTCTGGCATTTAACCAAAAGATGCCACACCTATCCTCTTAC
CAGCTCCTTTCAAATTCCTTCTGGTCCACAGGCTTCTTGCAGTATGGAAATGTGAGATTTGGGCTAAAGAAAAAATAGTTGTTTACCTAA
AGGGTTAAGTCCTAGGAAGGAAGTAGAAGTTTGGGAAATGAGGGATTCAAGGGCCACTCCTTCCACTGGAACTCTAAAACTATATAAACC
ATCTAAAACTGGAAATCTAGAACTATGTCAACTGTGTAGAACCTTGTCAGCATGGCAGATTTATTATACATTTCTGCAATATAAATGATA
AATGATACTGAACTAATTGCAAATGTTAGCATAAAGAGTGTTTTGATTTTTATAACAATTAGAAATGCTACAAGAATATTTAAAAATATT
CCTGATCATGAAAGCATTAATCAAATTAGAAAATCCAAGTCATTTTAAGAAGATAAAAATAGAAATTCAGGCAAGTTTGGGTGATGGGCG
GTATTCATCACAACCTTCATTTTATTCTTACAATTGAGCTTTGACTCAGGGGGAAAAGAAGTAAATGATTGTCAAGGTTCCCTCTGCCTT
GATTGATAGTTTCTGATGGGAGTGGGAAGGAAGGAATTGGAGTAATGGGTAGAATGGGAATGAGAGATTACGGGAGAGAGAGATGAGATG
GGTTGAACAGAAGAGGATGGGAACTGATGGTAGCTAGGAAGGAAAGCGTCAAGAAGGACCTGAATGTACCCAGCTTTTCTCCCCAAACTT
CAATACCACCTCAGGAAAAGGCCCACTGTGTCCAGGGGCGTCAGTCCAGCTCAATAGTGTCTAGCTTTTCAGAATCTTCTGATTGTTTGG
TCTTTAACAAAAACATAGCATCTATTTGCTAACAATAAACTTAAGCAACATATGATAATCATTTCATCTCCTTCCAAGAAGTGGTGAAAA
TGAACCAGGTGACATTAATTTAACTTCTGTTTTTGTTTATTTTTAATACAACCAAAAAGATATGCACATATTTTAATTTACATTATGGTA
CTGTATAATTTAAACCATAAACTGGTGCTGATTAATTTCTGCAACAAAGCAGCATATTAAATGTACTACATCTAGTGTTGTAGCAAAATT

>26337_26337_3_ELP4-FREM1_ELP4_chr11_31625454_ENST00000350638_FREM1_chr9_14816869_ENST00000422223_length(amino acids)=1548AA_BP=218
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNC
SEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVN
GCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVG
FEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSII
SAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKIL
KTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLL
RYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQ
IEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQ
LTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVD
QLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPS
LEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFD
PGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFH
LERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTI
KVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQ
KGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQ

--------------------------------------------------------------
>26337_26337_4_ELP4-FREM1_ELP4_chr11_31625454_ENST00000379163_FREM1_chr9_14816869_ENST00000380880_length(transcript)=4665nt_BP=671nt
ACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAAC
GTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCG
GTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTA
ATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTT
GCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGAT
GTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGCAGATTGGACCA
GTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTT
CTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGGATGACCTACTCTTGGAG
GTCACCGATGGCACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAGTCTTAAAGGCTGACCTC
ATGCCTGTCATGAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGGACAGCGATAACTTGAAG
TTGATGTTTGTGATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCTCTCAGAGAGATGTTATC
TCAGAGGCCGTGACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGGTGGTTTCGGATGGAGAG
GCTGGCCCTTTTGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAGTGTATGATCTCAACATC
ACGGTATACCCAGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCTCAACAGCCCTTACTGTT
AACCATTTGTCCGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGTTTGGCTACCTCGAAAAT
ATACTCCCTTCTGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGAACGCTTTTCACATTAAC
TATGTGCAGTCCAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGCATCACTCCTTGGAGATA
CCATTTTCTATTATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTGAGGGTCAGATGAAAGAG
CTGGACTCTTCCATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAAAGCCACGCCATGGCCTC
CTCATCGATAGGGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCACCTGTTCACAGCTTTTCC
ATGGAACTCCTCAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTACAATCCAATTGTCAGAT
GGGAAACATAAGATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCAAGAAGGCTGAAATTGCA
ATGAATATGGGTGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGAAGATTTACTATGTATTT
GAAAGGCTTCCCCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGAAATGCACTCAGGAGGAA
GTGGATCTGAACTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCTACCTTTGGGATGGCAAC
AACAGGTCCCCTGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAAAACCACTCGTGGTGTCT
AAAGGTGATAGAGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGCTCTATGTCATCACCTCC
CCTCCGCGATATGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATGTAGTGGGGCAGACAGTT
TGCTATGTACACAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGACCGAGCACGGGGTGTTT
GAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTT
TCCCCTGACCTCCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCCCCCAGCATGGCCAGCTC
TACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGAC
TCCCAGACTGACTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGTGGGAAGAACCTGTTTTA
TTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGC
TGCTACGGGATTTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCTTTAAAATTCTACAAGGC
CCAAAACATGGACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTT
TACATCATAAACCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACTCGGCCACTCCTCAAATT
TTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGA
AGGGGATATTCCATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATTTCACCGTGATTCCATCT
AAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTT
GAAGTAATTCTGAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACTCAAAAGGAGGACAATGC
CATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACC
ACTTCTGGTTCCTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACACCCTGCGGGGCTTTGAT
TCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATC
ATCTATAATTATCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCAAAGTATCCATCATTAGT
CAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAG
TTGCCCTCATTTCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGCTGTATCAGTGCAATGGG
ATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCAC
ATCTTGATCACAGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACCTTGTAACTGTATTCTCC
AGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAG
TGGATCGGTGGTGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGAGCTGTGTTTTGGTTCAA

>26337_26337_4_ELP4-FREM1_ELP4_chr11_31625454_ENST00000379163_FREM1_chr9_14816869_ENST00000380880_length(amino acids)=1549AA_BP=219
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSR
FGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMN
CSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFV
NGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSV
GFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSI
ISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKI
LKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNL
LRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYG
QIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLL
QLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQV
DQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINP
SLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQF
DPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSF
HLERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKT
IKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITE
QKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKW

--------------------------------------------------------------
>26337_26337_5_ELP4-FREM1_ELP4_chr11_31625454_ENST00000379163_FREM1_chr9_14816869_ENST00000380881_length(transcript)=7395nt_BP=671nt
ACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAAC
GTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCG
GTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTA
ATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTT
GCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGAT
GTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGCAGATTGGACCA
GTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTT
CTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGGATGACCTACTCTTGGAG
GTCACCGATGGCACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAGTCTTAAAGGCTGACCTC
ATGCCTGTCATGAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGGACAGCGATAACTTGAAG
TTGATGTTTGTGATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCTCTCAGAGAGATGTTATC
TCAGAGGCCGTGACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGGTGGTTTCGGATGGAGAG
GCTGGCCCTTTTGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAGTGTATGATCTCAACATC
ACGGTATACCCAGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCTCAACAGCCCTTACTGTT
AACCATTTGTCCGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGTTTGGCTACCTCGAAAAT
ATACTCCCTTCTGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGAACGCTTTTCACATTAAC
TATGTGCAGTCCAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGCATCACTCCTTGGAGATA
CCATTTTCTATTATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTGAGGGTCAGATGAAAGAG
CTGGACTCTTCCATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAAAGCCACGCCATGGCCTC
CTCATCGATAGGGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCACCTGTTCACAGCTTTTCC
ATGGAACTCCTCAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTACAATCCAATTGTCAGAT
GGGAAACATAAGATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCAAGAAGGCTGAAATTGCA
ATGAATATGGGTGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGAAGATTTACTATGTATTT
GAAAGGCTTCCCCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGAAATGCACTCAGGAGGAA
GTGGATCTGAACTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCTACCTTTGGGATGGCAAC
AACAGGTCCCCTGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAAAACCACTCGTGGTGTCT
AAAGGTGATAGAGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGCTCTATGTCATCACCTCC
CCTCCGCGATATGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATGTAGTGGGGCAGACAGTT
TGCTATGTACACAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGACCGAGCACGGGGTGTTT
GAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTT
TCCCCTGACCTCCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCCCCCAGCATGGCCAGCTC
TACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGAC
TCCCAGACTGACTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGTGGGAAGAACCTGTTTTA
TTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGC
TGCTACGGGATTTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCTTTAAAATTCTACAAGGC
CCAAAACATGGACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTT
TACATCATAAACCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACTCGGCCACTCCTCAAATT
TTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGA
AGGGGATATTCCATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATTTCACCGTGATTCCATCT
AAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTT
GAAGTAATTCTGAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACTCAAAAGGAGGACAATGC
CATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACC
ACTTCTGGTTCCTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACACCCTGCGGGGCTTTGAT
TCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATC
ATCTATAATTATCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCAAAGTATCCATCATTAGT
CAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAG
TTGCCCTCATTTCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGCTGTATCAGTGCAATGGG
ATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCAC
ATCTTGATCACAGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACCTTGTAACTGTATTCTCC
AGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAG
TGGATCGGTGGTGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGAGCTGTGTTTTGGTTCAA
AGACAAGGGAAATGGCAAACAAAAGACTGTAGGAGAGCCAAACCTCATAATTATGTGTGTTCCAGAAAACTCTAAATATAACAGACCCTA
CAGGGGGCCACCTGGAGTTTGTCACCTATTTATTCACAGGATCTGTGAATATTGCTCCATAGAAAACAAATTGTTATGATTGAGTGGGTA
TACCTTTGTGATTCTGTCTAGTGAAAATGGGACATTTTTAATAGTGCCAGAAAGATTGATAAATAAATATTTTTTACAAGATAAGATACA
ATTTTTGTATCTCAATACCTTTTAAAATAAATGCCAGCAGTATTATAAAGTGTAAGGTTTGTTTATTCCAGAAGACCCTCACCCTTACCC
CATTCCAAATCTCAGGGAGCACCAGTCTCATAGTCCTTGGATTTTTTTAAAAAAAATTTTTGGTCCCGTTACCTCTAATGAATTTATTCT
GAAATATGTATCGTAGGTGCTCCTACCACTTTAGTCTGAGTGAAGCTAACTCTACTAGTTCATTAAACCAAAGTTGAACCGCAAAGTTGT
CCCTTTGGAGCCCTTTAAATGTGAAATCTAAGATTAGAGGCTGGGGTTGAAAAAGAGAATTTTCTATGATGAAAAAGAAAGACTTTAGAT
GAAAGAATCTTGTAGGTGGAGGCTCATCTACAAAGCTGTAGTTCAGGTAAGAATTCGGGGGGCTGGCTGTACTCAGAGTTCTACTCATCA
CTATTCATGAAACAGATCTCCCTTTCCAATTTGAGTGTTGGCATTGTACCATCCCAAAGCTAATGATTGGGTTTCCCCAGCCTTACAGAG
TCATGAGAAATTTCAAGTAACATAATCTGTTCCTCTGTGTTTATTGTACTGACAAGCATTTCTCAGGGACACTTGGGATAAGGAGTATAT
ATGAATGATGGTTGACACATGGAAGAAAAATACTGCTTCCTCAGAAATGTCCTGATGAACTGTGCTGATGAACAGAGAAAAATAATACCG
AAAACAGAGCCCCTGAAAGCCTACATTCTCGGAAAGGATTTTGAGGAATTTTGAGCCACCTTAAATCTTTAATATTTGCAGAAATGCCAT
GTTAACTAGATTCTCTAACGGAAAGGTACCTTATTAATTTATAATCTCAGGTGAGTGGAACATTTTTGTAACAATGAAGTATGTTGCAGC
GTTACCAGAACTCCCTTCTGAAATCAAGGTTTAACAGTTATAGGAAATTAGAATGTCTGAAACATTTATTTAAAGTTTTTCTCTTTTCAT
AATCACTGAGAAATATGGTTGTGCCAAATGTCACTTGCTCTATGAGCACCAATGTAACTTCAGAATCAAATTGGGGTTATCAAGTAGGCT
AGAGCTCTGGTGCTGGTTTTATTATAAAAATACCTTGAGTGTTGTAGACACTAAAACTGCTTGAAGAAAGTCAGTTCAGTTTCTGGGATA
TAAAAACATGGCAAGCTTTTTTTATTTCAGTTCATTTATCAAGGTTGTAATTAATAGAAACATTTAGAAAGAGATATTGGAATATGATCC
AGACATTCTGTCTATTACTTAAATCTAAACATAATTATAGTGTCAGAGGGTCCTTACCTGAGATGTCGCAGGTGGGCTCCAGATTGGCAT
AATGTACAGGTTCTCTGTGAGACACAAGCAGTTTCTGGCATTTAACCAAAAGATGCCACACCTATCCTCTTACCAGCTCCTTTCAAATTC
CTTCTGGTCCACAGGCTTCTTGCAGTATGGAAATGTGAGATTTGGGCTAAAGAAAAAATAGTTGTTTACCTAAAGGGTTAAGTCCTAGGA
AGGAAGTAGAAGTTTGGGAAATGAGGGATTCAAGGGCCACTCCTTCCACTGGAACTCTAAAACTATATAAACCATCTAAAACTGGAAATC
TAGAACTATGTCAACTGTGTAGAACCTTGTCAGCATGGCAGATTTATTATACATTTCTGCAATATAAATGATAAATGATACTGAACTAAT
TGCAAATGTTAGCATAAAGAGTGTTTTGATTTTTATAACAATTAGAAATGCTACAAGAATATTTAAAAATATTCCTGATCATGAAAGCAT
TAATCAAATTAGAAAATCCAAGTCATTTTAAGAAGATAAAAATAGAAATTCAGGCAAGTTTGGGTGATGGGCGGTATTCATCACAACCTT
CATTTTATTCTTACAATTGAGCTTTGACTCAGGGGGAAAAGAAGTAAATGATTGTCAAGGTTCCCTCTGCCTTGATTGATAGTTTCTGAT
GGGAGTGGGAAGGAAGGAATTGGAGTAATGGGTAGAATGGGAATGAGAGATTACGGGAGAGAGAGATGAGATGGGTTGAACAGAAGAGGA
TGGGAACTGATGGTAGCTAGGAAGGAAAGCGTCAAGAAGGACCTGAATGTACCCAGCTTTTCTCCCCAAACTTCAATACCACCTCAGGAA
AAGGCCCACTGTGTCCAGGGGCGTCAGTCCAGCTCAATAGTGTCTAGCTTTTCAGAATCTTCTGATTGTTTGGTCTTTAACAAAAACATA
GCATCTATTTGCTAACAATAAACTTAAGCAACATATGATAATCATTTCATCTCCTTCCAAGAAGTGGTGAAAATGAACCAGGTGACATTA
ATTTAACTTCTGTTTTTGTTTATTTTTAATACAACCAAAAAGATATGCACATATTTTAATTTACATTATGGTACTGTATAATTTAAACCA
TAAACTGGTGCTGATTAATTTCTGCAACAAAGCAGCATATTAAATGTACTACATCTAGTGTTGTAGCAAAATTAATAAACTTGTTTTAAG

>26337_26337_5_ELP4-FREM1_ELP4_chr11_31625454_ENST00000379163_FREM1_chr9_14816869_ENST00000380881_length(amino acids)=1549AA_BP=219
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSR
FGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMN
CSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFV
NGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSV
GFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSI
ISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKI
LKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNL
LRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYG
QIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLL
QLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQV
DQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINP
SLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQF
DPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSF
HLERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKT
IKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITE
QKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKW

--------------------------------------------------------------
>26337_26337_6_ELP4-FREM1_ELP4_chr11_31625454_ENST00000379163_FREM1_chr9_14816869_ENST00000422223_length(transcript)=7395nt_BP=671nt
ACTGGAGGCTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAAC
GTCACCAGTTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCG
GTGCGGAATGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTA
ATTGAGGAGGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTT
GCATCTGCTAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGAT
GTATACAATCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGCAGATTGGACCA
GTATCATCTTCAAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTT
CTTCCAGAGAAAATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGGATGACCTACTCTTGGAG
GTCACCGATGGCACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAGTCTTAAAGGCTGACCTC
ATGCCTGTCATGAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGGACAGCGATAACTTGAAG
TTGATGTTTGTGATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCTCTCAGAGAGATGTTATC
TCAGAGGCCGTGACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGGTGGTTTCGGATGGAGAG
GCTGGCCCTTTTGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAGTGTATGATCTCAACATC
ACGGTATACCCAGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCTCAACAGCCCTTACTGTT
AACCATTTGTCCGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGTTTGGCTACCTCGAAAAT
ATACTCCCTTCTGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGAACGCTTTTCACATTAAC
TATGTGCAGTCCAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGCATCACTCCTTGGAGATA
CCATTTTCTATTATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTGAGGGTCAGATGAAAGAG
CTGGACTCTTCCATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAAAGCCACGCCATGGCCTC
CTCATCGATAGGGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCACCTGTTCACAGCTTTTCC
ATGGAACTCCTCAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTACAATCCAATTGTCAGAT
GGGAAACATAAGATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCAAGAAGGCTGAAATTGCA
ATGAATATGGGTGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGAAGATTTACTATGTATTT
GAAAGGCTTCCCCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGAAATGCACTCAGGAGGAA
GTGGATCTGAACTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCTACCTTTGGGATGGCAAC
AACAGGTCCCCTGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAAAACCACTCGTGGTGTCT
AAAGGTGATAGAGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGCTCTATGTCATCACCTCC
CCTCCGCGATATGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATGTAGTGGGGCAGACAGTT
TGCTATGTACACAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGACCGAGCACGGGGTGTTT
GAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTT
TCCCCTGACCTCCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCCCCCAGCATGGCCAGCTC
TACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGAC
TCCCAGACTGACTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGTGGGAAGAACCTGTTTTA
TTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGC
TGCTACGGGATTTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCTTTAAAATTCTACAAGGC
CCAAAACATGGACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTT
TACATCATAAACCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACTCGGCCACTCCTCAAATT
TTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGA
AGGGGATATTCCATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATTTCACCGTGATTCCATCT
AAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTT
GAAGTAATTCTGAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACTCAAAAGGAGGACAATGC
CATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACC
ACTTCTGGTTCCTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACACCCTGCGGGGCTTTGAT
TCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATC
ATCTATAATTATCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCAAAGTATCCATCATTAGT
CAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAG
TTGCCCTCATTTCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGCTGTATCAGTGCAATGGG
ATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCAC
ATCTTGATCACAGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACCTTGTAACTGTATTCTCC
AGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAG
TGGATCGGTGGTGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGAGCTGTGTTTTGGTTCAA
AGACAAGGGAAATGGCAAACAAAAGACTGTAGGAGAGCCAAACCTCATAATTATGTGTGTTCCAGAAAACTCTAAATATAACAGACCCTA
CAGGGGGCCACCTGGAGTTTGTCACCTATTTATTCACAGGATCTGTGAATATTGCTCCATAGAAAACAAATTGTTATGATTGAGTGGGTA
TACCTTTGTGATTCTGTCTAGTGAAAATGGGACATTTTTAATAGTGCCAGAAAGATTGATAAATAAATATTTTTTACAAGATAAGATACA
ATTTTTGTATCTCAATACCTTTTAAAATAAATGCCAGCAGTATTATAAAGTGTAAGGTTTGTTTATTCCAGAAGACCCTCACCCTTACCC
CATTCCAAATCTCAGGGAGCACCAGTCTCATAGTCCTTGGATTTTTTTAAAAAAAATTTTTGGTCCCGTTACCTCTAATGAATTTATTCT
GAAATATGTATCGTAGGTGCTCCTACCACTTTAGTCTGAGTGAAGCTAACTCTACTAGTTCATTAAACCAAAGTTGAACCGCAAAGTTGT
CCCTTTGGAGCCCTTTAAATGTGAAATCTAAGATTAGAGGCTGGGGTTGAAAAAGAGAATTTTCTATGATGAAAAAGAAAGACTTTAGAT
GAAAGAATCTTGTAGGTGGAGGCTCATCTACAAAGCTGTAGTTCAGGTAAGAATTCGGGGGGCTGGCTGTACTCAGAGTTCTACTCATCA
CTATTCATGAAACAGATCTCCCTTTCCAATTTGAGTGTTGGCATTGTACCATCCCAAAGCTAATGATTGGGTTTCCCCAGCCTTACAGAG
TCATGAGAAATTTCAAGTAACATAATCTGTTCCTCTGTGTTTATTGTACTGACAAGCATTTCTCAGGGACACTTGGGATAAGGAGTATAT
ATGAATGATGGTTGACACATGGAAGAAAAATACTGCTTCCTCAGAAATGTCCTGATGAACTGTGCTGATGAACAGAGAAAAATAATACCG
AAAACAGAGCCCCTGAAAGCCTACATTCTCGGAAAGGATTTTGAGGAATTTTGAGCCACCTTAAATCTTTAATATTTGCAGAAATGCCAT
GTTAACTAGATTCTCTAACGGAAAGGTACCTTATTAATTTATAATCTCAGGTGAGTGGAACATTTTTGTAACAATGAAGTATGTTGCAGC
GTTACCAGAACTCCCTTCTGAAATCAAGGTTTAACAGTTATAGGAAATTAGAATGTCTGAAACATTTATTTAAAGTTTTTCTCTTTTCAT
AATCACTGAGAAATATGGTTGTGCCAAATGTCACTTGCTCTATGAGCACCAATGTAACTTCAGAATCAAATTGGGGTTATCAAGTAGGCT
AGAGCTCTGGTGCTGGTTTTATTATAAAAATACCTTGAGTGTTGTAGACACTAAAACTGCTTGAAGAAAGTCAGTTCAGTTTCTGGGATA
TAAAAACATGGCAAGCTTTTTTTATTTCAGTTCATTTATCAAGGTTGTAATTAATAGAAACATTTAGAAAGAGATATTGGAATATGATCC
AGACATTCTGTCTATTACTTAAATCTAAACATAATTATAGTGTCAGAGGGTCCTTACCTGAGATGTCGCAGGTGGGCTCCAGATTGGCAT
AATGTACAGGTTCTCTGTGAGACACAAGCAGTTTCTGGCATTTAACCAAAAGATGCCACACCTATCCTCTTACCAGCTCCTTTCAAATTC
CTTCTGGTCCACAGGCTTCTTGCAGTATGGAAATGTGAGATTTGGGCTAAAGAAAAAATAGTTGTTTACCTAAAGGGTTAAGTCCTAGGA
AGGAAGTAGAAGTTTGGGAAATGAGGGATTCAAGGGCCACTCCTTCCACTGGAACTCTAAAACTATATAAACCATCTAAAACTGGAAATC
TAGAACTATGTCAACTGTGTAGAACCTTGTCAGCATGGCAGATTTATTATACATTTCTGCAATATAAATGATAAATGATACTGAACTAAT
TGCAAATGTTAGCATAAAGAGTGTTTTGATTTTTATAACAATTAGAAATGCTACAAGAATATTTAAAAATATTCCTGATCATGAAAGCAT
TAATCAAATTAGAAAATCCAAGTCATTTTAAGAAGATAAAAATAGAAATTCAGGCAAGTTTGGGTGATGGGCGGTATTCATCACAACCTT
CATTTTATTCTTACAATTGAGCTTTGACTCAGGGGGAAAAGAAGTAAATGATTGTCAAGGTTCCCTCTGCCTTGATTGATAGTTTCTGAT
GGGAGTGGGAAGGAAGGAATTGGAGTAATGGGTAGAATGGGAATGAGAGATTACGGGAGAGAGAGATGAGATGGGTTGAACAGAAGAGGA
TGGGAACTGATGGTAGCTAGGAAGGAAAGCGTCAAGAAGGACCTGAATGTACCCAGCTTTTCTCCCCAAACTTCAATACCACCTCAGGAA
AAGGCCCACTGTGTCCAGGGGCGTCAGTCCAGCTCAATAGTGTCTAGCTTTTCAGAATCTTCTGATTGTTTGGTCTTTAACAAAAACATA
GCATCTATTTGCTAACAATAAACTTAAGCAACATATGATAATCATTTCATCTCCTTCCAAGAAGTGGTGAAAATGAACCAGGTGACATTA
ATTTAACTTCTGTTTTTGTTTATTTTTAATACAACCAAAAAGATATGCACATATTTTAATTTACATTATGGTACTGTATAATTTAAACCA
TAAACTGGTGCTGATTAATTTCTGCAACAAAGCAGCATATTAAATGTACTACATCTAGTGTTGTAGCAAAATTAATAAACTTGTTTTAAG

>26337_26337_6_ELP4-FREM1_ELP4_chr11_31625454_ENST00000379163_FREM1_chr9_14816869_ENST00000422223_length(amino acids)=1549AA_BP=219
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSR
FGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMN
CSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFV
NGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSV
GFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSI
ISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKI
LKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNL
LRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYG
QIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLL
QLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQV
DQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINP
SLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQF
DPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSF
HLERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKT
IKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITE
QKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKW

--------------------------------------------------------------
>26337_26337_7_ELP4-FREM1_ELP4_chr11_31625454_ENST00000395934_FREM1_chr9_14816869_ENST00000380880_length(transcript)=4654nt_BP=660nt
CTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAACGTCACCAG
TTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCGGTGCGGAA
TGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTAATTGAGGA
GGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTTGCATCTGC
TAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGATGTATACAA
TCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGATTGGACCAGTATCATCTTC
AAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTTCTTCCAGAGAA
AATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGGATGACCTACTCTTGGAGGTCACCGATGG
CACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAGTCTTAAAGGCTGACCTCATGCCTGTCAT
GAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGGACAGCGATAACTTGAAGTTGATGTTTGT
GATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCTCTCAGAGAGATGTTATCTCAGAGGCCGT
GACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGGTGGTTTCGGATGGAGAGGCTGGCCCTTT
TGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAGTGTATGATCTCAACATCACGGTATACCC
AGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCTCAACAGCCCTTACTGTTAACCATTTGTC
CGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGTTTGGCTACCTCGAAAATATACTCCCTTC
TGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGAACGCTTTTCACATTAACTATGTGCAGTC
CAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGCATCACTCCTTGGAGATACCATTTTCTAT
TATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTGAGGGTCAGATGAAAGAGCTGGACTCTTC
CATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAAAGCCACGCCATGGCCTCCTCATCGATAG
GGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCACCTGTTCACAGCTTTTCCATGGAACTCCT
CAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTACAATCCAATTGTCAGATGGGAAACATAA
GATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCAAGAAGGCTGAAATTGCAATGAATATGGG
TGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGAAGATTTACTATGTATTTGAAAGGCTTCC
CCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGAAATGCACTCAGGAGGAAGTGGATCTGAA
CTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCTACCTTTGGGATGGCAACAACAGGTCCCC
TGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAAAACCACTCGTGGTGTCTAAAGGTGATAG
AGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGCTCTATGTCATCACCTCCCCTCCGCGATA
TGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATGTAGTGGGGCAGACAGTTTGCTATGTACA
CAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGACCGAGCACGGGGTGTTTGAGATCACACT
GGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTTTCCCCTGACCT
CCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCCCCCAGCATGGCCAGCTCTACCTGTGGGG
GACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGACTCCCAGACTGA
CTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGTGGGAAGAACCTGTTTTATTCACCATTCA
GGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGCTGCTACGGGAT
TTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCTTTAAAATTCTACAAGGCCCAAAACATGG
ACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTTTACATCATAAA
CCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACTCGGCCACTCCTCAAATTTTGGAACTGAA
GTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGAAGGGGATATTC
CATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATTTCACCGTGATTCCATCTAAACTGATTCA
GTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTTGAAGTAATTCT
GAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACTCAAAAGGAGGACAATGCCATCCTTCATA
TTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACCACTTCTGGTTC
CTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACACCCTGCGGGGCTTTGATTCTACAGATCT
TTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATCATCTATAATTA
TCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCAAAGTATCCATCATTAGTCAGCCACAAAA
GACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAGTTGCCCTCATT
TCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGCTGTATCAGTGCAATGGGATCGCCTGGAA
AGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCACATCTTGATCAC
AGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACCTTGTAACTGTATTCTCCAGGCAGCACAT
GCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAGTGGATCGGTGG
TGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGAGCTGTGTTTTGGTTCAAAGACAAGGGAA

>26337_26337_7_ELP4-FREM1_ELP4_chr11_31625454_ENST00000395934_FREM1_chr9_14816869_ENST00000380880_length(amino acids)=1549AA_BP=218
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNC
SEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVN
GCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVG
FEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSII
SAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKIL
KTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLL
RYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQ
IEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQ
LTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVD
QLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPS
LEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFD
PGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFH
LERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTI
KVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQ
KGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQ

--------------------------------------------------------------
>26337_26337_8_ELP4-FREM1_ELP4_chr11_31625454_ENST00000395934_FREM1_chr9_14816869_ENST00000380881_length(transcript)=7384nt_BP=660nt
CTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAACGTCACCAG
TTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCGGTGCGGAA
TGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTAATTGAGGA
GGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTTGCATCTGC
TAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGATGTATACAA
TCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGATTGGACCAGTATCATCTTC
AAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTTCTTCCAGAGAA
AATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGGATGACCTACTCTTGGAGGTCACCGATGG
CACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAGTCTTAAAGGCTGACCTCATGCCTGTCAT
GAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGGACAGCGATAACTTGAAGTTGATGTTTGT
GATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCTCTCAGAGAGATGTTATCTCAGAGGCCGT
GACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGGTGGTTTCGGATGGAGAGGCTGGCCCTTT
TGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAGTGTATGATCTCAACATCACGGTATACCC
AGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCTCAACAGCCCTTACTGTTAACCATTTGTC
CGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGTTTGGCTACCTCGAAAATATACTCCCTTC
TGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGAACGCTTTTCACATTAACTATGTGCAGTC
CAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGCATCACTCCTTGGAGATACCATTTTCTAT
TATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTGAGGGTCAGATGAAAGAGCTGGACTCTTC
CATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAAAGCCACGCCATGGCCTCCTCATCGATAG
GGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCACCTGTTCACAGCTTTTCCATGGAACTCCT
CAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTACAATCCAATTGTCAGATGGGAAACATAA
GATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCAAGAAGGCTGAAATTGCAATGAATATGGG
TGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGAAGATTTACTATGTATTTGAAAGGCTTCC
CCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGAAATGCACTCAGGAGGAAGTGGATCTGAA
CTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCTACCTTTGGGATGGCAACAACAGGTCCCC
TGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAAAACCACTCGTGGTGTCTAAAGGTGATAG
AGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGCTCTATGTCATCACCTCCCCTCCGCGATA
TGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATGTAGTGGGGCAGACAGTTTGCTATGTACA
CAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGACCGAGCACGGGGTGTTTGAGATCACACT
GGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTTTCCCCTGACCT
CCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCCCCCAGCATGGCCAGCTCTACCTGTGGGG
GACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGACTCCCAGACTGA
CTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGTGGGAAGAACCTGTTTTATTCACCATTCA
GGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGCTGCTACGGGAT
TTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCTTTAAAATTCTACAAGGCCCAAAACATGG
ACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTTTACATCATAAA
CCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACTCGGCCACTCCTCAAATTTTGGAACTGAA
GTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGAAGGGGATATTC
CATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATTTCACCGTGATTCCATCTAAACTGATTCA
GTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTTGAAGTAATTCT
GAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACTCAAAAGGAGGACAATGCCATCCTTCATA
TTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACCACTTCTGGTTC
CTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACACCCTGCGGGGCTTTGATTCTACAGATCT
TTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATCATCTATAATTA
TCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCAAAGTATCCATCATTAGTCAGCCACAAAA
GACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAGTTGCCCTCATT
TCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGCTGTATCAGTGCAATGGGATCGCCTGGAA
AGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCACATCTTGATCAC
AGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACCTTGTAACTGTATTCTCCAGGCAGCACAT
GCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAGTGGATCGGTGG
TGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGAGCTGTGTTTTGGTTCAAAGACAAGGGAA
ATGGCAAACAAAAGACTGTAGGAGAGCCAAACCTCATAATTATGTGTGTTCCAGAAAACTCTAAATATAACAGACCCTACAGGGGGCCAC
CTGGAGTTTGTCACCTATTTATTCACAGGATCTGTGAATATTGCTCCATAGAAAACAAATTGTTATGATTGAGTGGGTATACCTTTGTGA
TTCTGTCTAGTGAAAATGGGACATTTTTAATAGTGCCAGAAAGATTGATAAATAAATATTTTTTACAAGATAAGATACAATTTTTGTATC
TCAATACCTTTTAAAATAAATGCCAGCAGTATTATAAAGTGTAAGGTTTGTTTATTCCAGAAGACCCTCACCCTTACCCCATTCCAAATC
TCAGGGAGCACCAGTCTCATAGTCCTTGGATTTTTTTAAAAAAAATTTTTGGTCCCGTTACCTCTAATGAATTTATTCTGAAATATGTAT
CGTAGGTGCTCCTACCACTTTAGTCTGAGTGAAGCTAACTCTACTAGTTCATTAAACCAAAGTTGAACCGCAAAGTTGTCCCTTTGGAGC
CCTTTAAATGTGAAATCTAAGATTAGAGGCTGGGGTTGAAAAAGAGAATTTTCTATGATGAAAAAGAAAGACTTTAGATGAAAGAATCTT
GTAGGTGGAGGCTCATCTACAAAGCTGTAGTTCAGGTAAGAATTCGGGGGGCTGGCTGTACTCAGAGTTCTACTCATCACTATTCATGAA
ACAGATCTCCCTTTCCAATTTGAGTGTTGGCATTGTACCATCCCAAAGCTAATGATTGGGTTTCCCCAGCCTTACAGAGTCATGAGAAAT
TTCAAGTAACATAATCTGTTCCTCTGTGTTTATTGTACTGACAAGCATTTCTCAGGGACACTTGGGATAAGGAGTATATATGAATGATGG
TTGACACATGGAAGAAAAATACTGCTTCCTCAGAAATGTCCTGATGAACTGTGCTGATGAACAGAGAAAAATAATACCGAAAACAGAGCC
CCTGAAAGCCTACATTCTCGGAAAGGATTTTGAGGAATTTTGAGCCACCTTAAATCTTTAATATTTGCAGAAATGCCATGTTAACTAGAT
TCTCTAACGGAAAGGTACCTTATTAATTTATAATCTCAGGTGAGTGGAACATTTTTGTAACAATGAAGTATGTTGCAGCGTTACCAGAAC
TCCCTTCTGAAATCAAGGTTTAACAGTTATAGGAAATTAGAATGTCTGAAACATTTATTTAAAGTTTTTCTCTTTTCATAATCACTGAGA
AATATGGTTGTGCCAAATGTCACTTGCTCTATGAGCACCAATGTAACTTCAGAATCAAATTGGGGTTATCAAGTAGGCTAGAGCTCTGGT
GCTGGTTTTATTATAAAAATACCTTGAGTGTTGTAGACACTAAAACTGCTTGAAGAAAGTCAGTTCAGTTTCTGGGATATAAAAACATGG
CAAGCTTTTTTTATTTCAGTTCATTTATCAAGGTTGTAATTAATAGAAACATTTAGAAAGAGATATTGGAATATGATCCAGACATTCTGT
CTATTACTTAAATCTAAACATAATTATAGTGTCAGAGGGTCCTTACCTGAGATGTCGCAGGTGGGCTCCAGATTGGCATAATGTACAGGT
TCTCTGTGAGACACAAGCAGTTTCTGGCATTTAACCAAAAGATGCCACACCTATCCTCTTACCAGCTCCTTTCAAATTCCTTCTGGTCCA
CAGGCTTCTTGCAGTATGGAAATGTGAGATTTGGGCTAAAGAAAAAATAGTTGTTTACCTAAAGGGTTAAGTCCTAGGAAGGAAGTAGAA
GTTTGGGAAATGAGGGATTCAAGGGCCACTCCTTCCACTGGAACTCTAAAACTATATAAACCATCTAAAACTGGAAATCTAGAACTATGT
CAACTGTGTAGAACCTTGTCAGCATGGCAGATTTATTATACATTTCTGCAATATAAATGATAAATGATACTGAACTAATTGCAAATGTTA
GCATAAAGAGTGTTTTGATTTTTATAACAATTAGAAATGCTACAAGAATATTTAAAAATATTCCTGATCATGAAAGCATTAATCAAATTA
GAAAATCCAAGTCATTTTAAGAAGATAAAAATAGAAATTCAGGCAAGTTTGGGTGATGGGCGGTATTCATCACAACCTTCATTTTATTCT
TACAATTGAGCTTTGACTCAGGGGGAAAAGAAGTAAATGATTGTCAAGGTTCCCTCTGCCTTGATTGATAGTTTCTGATGGGAGTGGGAA
GGAAGGAATTGGAGTAATGGGTAGAATGGGAATGAGAGATTACGGGAGAGAGAGATGAGATGGGTTGAACAGAAGAGGATGGGAACTGAT
GGTAGCTAGGAAGGAAAGCGTCAAGAAGGACCTGAATGTACCCAGCTTTTCTCCCCAAACTTCAATACCACCTCAGGAAAAGGCCCACTG
TGTCCAGGGGCGTCAGTCCAGCTCAATAGTGTCTAGCTTTTCAGAATCTTCTGATTGTTTGGTCTTTAACAAAAACATAGCATCTATTTG
CTAACAATAAACTTAAGCAACATATGATAATCATTTCATCTCCTTCCAAGAAGTGGTGAAAATGAACCAGGTGACATTAATTTAACTTCT
GTTTTTGTTTATTTTTAATACAACCAAAAAGATATGCACATATTTTAATTTACATTATGGTACTGTATAATTTAAACCATAAACTGGTGC
TGATTAATTTCTGCAACAAAGCAGCATATTAAATGTACTACATCTAGTGTTGTAGCAAAATTAATAAACTTGTTTTAAGTTCTGAGACAC

>26337_26337_8_ELP4-FREM1_ELP4_chr11_31625454_ENST00000395934_FREM1_chr9_14816869_ENST00000380881_length(amino acids)=1548AA_BP=218
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNC
SEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVN
GCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVG
FEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSII
SAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKIL
KTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLL
RYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQ
IEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQ
LTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVD
QLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPS
LEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFD
PGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFH
LERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTI
KVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQ
KGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQ

--------------------------------------------------------------
>26337_26337_9_ELP4-FREM1_ELP4_chr11_31625454_ENST00000395934_FREM1_chr9_14816869_ENST00000422223_length(transcript)=7384nt_BP=660nt
CTCTAAGATGGCGGCAGTGGCAACCTGCGGTAGTGTTGCCGCGAGTACTGGGTCTGCAGTGGCGACAGCCAGCAAGAGCAACGTCACCAG
TTTCCAGAGGAGGGGTCCTAGAGCCAGCGTGACCAACGACAGCGGCCCTCGACTGGTGTCCATTGCGGGCACGCGACCGTCGGTGCGGAA
TGGACAGCTGCTGGTATCAACCGGGCTCCCAGCCCTAGACCAGCTCTTAGGTGGAGGTTTAGCCGTTGGAACAGTTCTTCTAATTGAGGA
GGATAAATATAATATTTACTCACCTTTGCTCTTCAAGTATTTCCTGGCAGAAGGAATTGTCAATGGGCATACTTTGTTGGTTGCATCTGC
TAAAGAGGATCCTGCCAACATTTTACAGGAACTTCCAGCACCATTACTTGATGATAAATGTAAAAAGGAATTTGATGAAGATGTATACAA
TCATAAAACACCAGAATCTAATATTAAGATGAAAATAGCTTGGCGTTACCAGTTATTACCCAAGATGGAGATTGGACCAGTATCATCTTC
AAGATTTGGTCACTATTATGATGCATCAAAAAGAATGCCACAAGAACTAATTGAGGCTTCAAATTGGCATGGATTTTTTCTTCCAGAGAA
AATATCTTCAACTCTCAAAGTAGAACCCTGGTATCAACATGATGGAACTGAAGTTCTTCAGGATGACCTACTCTTGGAGGTCACCGATGG
CACAAATTCAGCAGAATTTGTACTACATGTTGAGGTATTCCCTGTCAACGATGAGCCACCAGTCTTAAAGGCTGACCTCATGCCTGTCAT
GAATTGCTCAGAGGGAGGAGAGGTGGTCATCACCTCTGAATACATTTTTGCTACTGATGTGGACAGCGATAACTTGAAGTTGATGTTTGT
GATTGCTCGCGAACCTCAGCATGGGGTGGTGAGGAGAGCTGGAGTCACAGTGGATCAGTTCTCTCAGAGAGATGTTATCTCAGAGGCCGT
GACATACAAACACACAGGTGGCGAGATTGGCCTGATGCCTTGTTTTGACACCATTACATTGGTGGTTTCGGATGGAGAGGCTGGCCCTTT
TGTGAATGGCTGTTGCTACAATGGACCCAATCCATCTGTTCCACTTCATGCGTCCTTTCCAGTGTATGATCTCAACATCACGGTATACCC
AGTAGACAACCAGCCACCTTCCATTGCAATAGGTCCCGTGTTTGTTGTAGATGAGGGCTGCTCAACAGCCCTTACTGTTAACCATTTGTC
CGCCACTGACCCTGACACTGCAGCAGATGACTTGGAATTTGTTTTGGTTTCTCCTCCTCAGTTTGGCTACCTCGAAAATATACTCCCTTC
TGTGGGTTTTGAAAAAAGCAATATTGGCATAAGTATAGATTCATTTCAGTGGAAAGACATGAACGCTTTTCACATTAACTATGTGCAGTC
CAGGCATCTGAGGATAGAACCAACTGCCGACCAGTTCACGGTGTACGTCACAGATGGGAAGCATCACTCCTTGGAGATACCATTTTCTAT
TATAATCAACCCCACAAATGATGAAGCTCCTGACTTTGTAGTGCAGAATATTACTGTGTGTGAGGGTCAGATGAAAGAGCTGGACTCTTC
CATCATCAGCGCTGTGGACCTGGACATTCCCCAGGATGCCCTGCTGTTCAGCATCACTCAAAAGCCACGCCATGGCCTCCTCATCGATAG
GGGGTTTAGCAAAGACTTCTCTGAGAATAAGCAGCCAGCCAACCCTCACCAGAAACATGCACCTGTTCACAGCTTTTCCATGGAACTCCT
CAAGACTGGAATGAGGTTGACGTACATGCATGATGACTCAGAGAGCCTTGCTGATGATTTTACAATCCAATTGTCAGATGGGAAACATAA
GATACTTAAAACCATTTCAGTAGAGGTCATCCCAGTTAATGATGAAAAACCAATGCTGAGCAAGAAGGCTGAAATTGCAATGAATATGGG
TGAAACTCGTATTATTTCCAGTGCTATTCTTTCAGCCATAGATGAAGACTCACCCAGGGAGAAGATTTACTATGTATTTGAAAGGCTTCC
CCAAAATGGGCAACTTCAGCTTAAGATAGGGAGGGACTGGGTTCCTCTCTCCCCTGGCATGAAATGCACTCAGGAGGAAGTGGATCTGAA
CTTGCTGAGATACACACACACCGGGGCAATGGATTCCCAGAATCAAGATAGCTTCACCTTCTACCTTTGGGATGGCAACAACAGGTCCCC
TGCTCTTGACTGTCAAATCACCATCAAGGACATGGAAAAAGGTGATATTGTCATCCTTACAAAACCACTCGTGGTGTCTAAAGGTGATAG
AGGTTTCTTAACAACCACCACGCTCCTGGCTGTGGACGGAACAGACAAGCCTGAGGAACTGCTCTATGTCATCACCTCCCCTCCGCGATA
TGGCCAGATCGAATATGTTCACTATCCTGGAGTTCCCATTACAAACTTCAGCCAAATGGATGTAGTGGGGCAGACAGTTTGCTATGTACA
CAAGAGCAAGGTGACTGTCTCCAGTGACAGATTCAGATTCATCATCAGCAATGGACTGCGGACCGAGCACGGGGTGTTTGAGATCACACT
GGAGACTGTGGACAGAGCCCTGCCTGTGGTAACCAGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTTTCCCCTGACCT
CCTTCAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCCCCCAGCATGGCCAGCTCTACCTGTGGGG
GACAGGGCTACTTCAACACAATTTCACCCAGCAGGATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGACTCCCAGACTGA
CTGCTTTACTTTCATGGCCACAGATGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGTGGGAAGAACCTGTTTTATTCACCATTCA
GGTAGACCAATTGGACAAAACAGCTCCTCGTATCACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGCTGCTACGGGAT
TTACATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCTTTAAAATTCTACAAGGCCCAAAACATGG
ACATCTGGAGAACACAACAACAGGTGAATTTATCCATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTTTACATCATAAA
CCCATCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACTCGGCCACTCCTCAAATTTTGGAACTGAA
GTGGTCTCATATTGAATGGTCACAGACCGAATATGAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGAAGGGGATATTC
CATGGACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATTTCACCGTGATTCCATCTAAACTGATTCA
GTTTGACCCAGGAATGTCAACTAAGATGTGGAATATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTTGAAGTAATTCT
GAACTCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACTCAAAAGGAGGACAATGCCATCCTTCATA
TTCCTCCAACCAAAGCAAGCACAGCACATGGGAGAAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACCACTTCTGGTTC
CTTTCATCTGGAAAGAAGACCTCTTCCATCTTCCATGCAGCTAGCAGTCATCAGGGGAGACACCCTGCGGGGCTTTGATTCTACAGATCT
TTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGCAAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATCATCTATAATTA
TCATGGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCAAAGTATCCATCATTAGTCAGCCACAAAA
GACAATCAAAGTGGCAGAACTGCCTCAAGCAGATAAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAGTTGCCCTCATT
TCCAAAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGCTGTATCAGTGCAATGGGATCGCCTGGAA
AGCCTGGAGTCCCCAAACCAAGGATGTGGAAGACAAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCACATCTTGATCAC
AGAGCAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACCTTGTAACTGTATTCTCCAGGCAGCACAT
GCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCCTTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAGTGGATCGGTGG
TGAACCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCAACGCTCCAAGCTTGGAAAGAGCTGTGTTTTGGTTCAAAGACAAGGGAA
ATGGCAAACAAAAGACTGTAGGAGAGCCAAACCTCATAATTATGTGTGTTCCAGAAAACTCTAAATATAACAGACCCTACAGGGGGCCAC
CTGGAGTTTGTCACCTATTTATTCACAGGATCTGTGAATATTGCTCCATAGAAAACAAATTGTTATGATTGAGTGGGTATACCTTTGTGA
TTCTGTCTAGTGAAAATGGGACATTTTTAATAGTGCCAGAAAGATTGATAAATAAATATTTTTTACAAGATAAGATACAATTTTTGTATC
TCAATACCTTTTAAAATAAATGCCAGCAGTATTATAAAGTGTAAGGTTTGTTTATTCCAGAAGACCCTCACCCTTACCCCATTCCAAATC
TCAGGGAGCACCAGTCTCATAGTCCTTGGATTTTTTTAAAAAAAATTTTTGGTCCCGTTACCTCTAATGAATTTATTCTGAAATATGTAT
CGTAGGTGCTCCTACCACTTTAGTCTGAGTGAAGCTAACTCTACTAGTTCATTAAACCAAAGTTGAACCGCAAAGTTGTCCCTTTGGAGC
CCTTTAAATGTGAAATCTAAGATTAGAGGCTGGGGTTGAAAAAGAGAATTTTCTATGATGAAAAAGAAAGACTTTAGATGAAAGAATCTT
GTAGGTGGAGGCTCATCTACAAAGCTGTAGTTCAGGTAAGAATTCGGGGGGCTGGCTGTACTCAGAGTTCTACTCATCACTATTCATGAA
ACAGATCTCCCTTTCCAATTTGAGTGTTGGCATTGTACCATCCCAAAGCTAATGATTGGGTTTCCCCAGCCTTACAGAGTCATGAGAAAT
TTCAAGTAACATAATCTGTTCCTCTGTGTTTATTGTACTGACAAGCATTTCTCAGGGACACTTGGGATAAGGAGTATATATGAATGATGG
TTGACACATGGAAGAAAAATACTGCTTCCTCAGAAATGTCCTGATGAACTGTGCTGATGAACAGAGAAAAATAATACCGAAAACAGAGCC
CCTGAAAGCCTACATTCTCGGAAAGGATTTTGAGGAATTTTGAGCCACCTTAAATCTTTAATATTTGCAGAAATGCCATGTTAACTAGAT
TCTCTAACGGAAAGGTACCTTATTAATTTATAATCTCAGGTGAGTGGAACATTTTTGTAACAATGAAGTATGTTGCAGCGTTACCAGAAC
TCCCTTCTGAAATCAAGGTTTAACAGTTATAGGAAATTAGAATGTCTGAAACATTTATTTAAAGTTTTTCTCTTTTCATAATCACTGAGA
AATATGGTTGTGCCAAATGTCACTTGCTCTATGAGCACCAATGTAACTTCAGAATCAAATTGGGGTTATCAAGTAGGCTAGAGCTCTGGT
GCTGGTTTTATTATAAAAATACCTTGAGTGTTGTAGACACTAAAACTGCTTGAAGAAAGTCAGTTCAGTTTCTGGGATATAAAAACATGG
CAAGCTTTTTTTATTTCAGTTCATTTATCAAGGTTGTAATTAATAGAAACATTTAGAAAGAGATATTGGAATATGATCCAGACATTCTGT
CTATTACTTAAATCTAAACATAATTATAGTGTCAGAGGGTCCTTACCTGAGATGTCGCAGGTGGGCTCCAGATTGGCATAATGTACAGGT
TCTCTGTGAGACACAAGCAGTTTCTGGCATTTAACCAAAAGATGCCACACCTATCCTCTTACCAGCTCCTTTCAAATTCCTTCTGGTCCA
CAGGCTTCTTGCAGTATGGAAATGTGAGATTTGGGCTAAAGAAAAAATAGTTGTTTACCTAAAGGGTTAAGTCCTAGGAAGGAAGTAGAA
GTTTGGGAAATGAGGGATTCAAGGGCCACTCCTTCCACTGGAACTCTAAAACTATATAAACCATCTAAAACTGGAAATCTAGAACTATGT
CAACTGTGTAGAACCTTGTCAGCATGGCAGATTTATTATACATTTCTGCAATATAAATGATAAATGATACTGAACTAATTGCAAATGTTA
GCATAAAGAGTGTTTTGATTTTTATAACAATTAGAAATGCTACAAGAATATTTAAAAATATTCCTGATCATGAAAGCATTAATCAAATTA
GAAAATCCAAGTCATTTTAAGAAGATAAAAATAGAAATTCAGGCAAGTTTGGGTGATGGGCGGTATTCATCACAACCTTCATTTTATTCT
TACAATTGAGCTTTGACTCAGGGGGAAAAGAAGTAAATGATTGTCAAGGTTCCCTCTGCCTTGATTGATAGTTTCTGATGGGAGTGGGAA
GGAAGGAATTGGAGTAATGGGTAGAATGGGAATGAGAGATTACGGGAGAGAGAGATGAGATGGGTTGAACAGAAGAGGATGGGAACTGAT
GGTAGCTAGGAAGGAAAGCGTCAAGAAGGACCTGAATGTACCCAGCTTTTCTCCCCAAACTTCAATACCACCTCAGGAAAAGGCCCACTG
TGTCCAGGGGCGTCAGTCCAGCTCAATAGTGTCTAGCTTTTCAGAATCTTCTGATTGTTTGGTCTTTAACAAAAACATAGCATCTATTTG
CTAACAATAAACTTAAGCAACATATGATAATCATTTCATCTCCTTCCAAGAAGTGGTGAAAATGAACCAGGTGACATTAATTTAACTTCT
GTTTTTGTTTATTTTTAATACAACCAAAAAGATATGCACATATTTTAATTTACATTATGGTACTGTATAATTTAAACCATAAACTGGTGC
TGATTAATTTCTGCAACAAAGCAGCATATTAAATGTACTACATCTAGTGTTGTAGCAAAATTAATAAACTTGTTTTAAGTTCTGAGACAC

>26337_26337_9_ELP4-FREM1_ELP4_chr11_31625454_ENST00000395934_FREM1_chr9_14816869_ENST00000422223_length(amino acids)=1548AA_BP=218
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDK
YNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEIGPVSSSRF
GHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPWYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNC
SEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVN
GCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVG
FEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSII
SAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKIL
KTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLL
RYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQ
IEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQ
LTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVD
QLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIINPS
LEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFD
PGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSSTTSGSFH
LERRPLPSSMQLAVIRGDTLRGFDSTDLSQRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKTI
KVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQ
KGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQ

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Fusion Gene PPI Analysis for ELP4-FREM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ELP4-FREM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ELP4-FREM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource