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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EMC1-KNTC1 (FusionGDB2 ID:26363)

Fusion Gene Summary for EMC1-KNTC1

check button Fusion gene summary
Fusion gene informationFusion gene name: EMC1-KNTC1
Fusion gene ID: 26363
HgeneTgene
Gene symbol

EMC1

KNTC1

Gene ID

23065

9735

Gene nameER membrane protein complex subunit 1kinetochore associated 1
SynonymsCAVIPMR|KIAA0090ROD
Cytomap

1p36.13

12q24.31

Type of geneprotein-codingprotein-coding
DescriptionER membrane protein complex subunit 1kinetochore-associated protein 1Rough Deal homolog, centromere/kinetochore protein
Modification date2020031320200313
UniProtAcc

Q8N766

P50748

Ensembl transtripts involved in fusion geneENST00000375199, ENST00000375208, 
ENST00000477853, ENST00000356068, 
ENST00000480380, 		ENST00000436959, 
ENST00000534995, ENST00000537348, 
ENST00000545065, ENST00000333479, 
ENST00000450485, 
Fusion gene scores* DoF score4 X 4 X 3=4811 X 16 X 6=1056
# samples 414
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1056*10)=-2.91511110241349
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EMC1 [Title/Abstract] AND KNTC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEMC1(19553807)-KNTC1(123097657), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneKNTC1

GO:0007093

mitotic cell cycle checkpoint

11146660


check buttonFusion gene breakpoints across EMC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KNTC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAA303951EMC1chr1

19553807

-KNTC1chr12

123097657

+
ChiTaRS5.0N/AAW960543EMC1chr1

19553807

-KNTC1chr12

123097657

+


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Fusion Gene ORF analysis for EMC1-KNTC1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000375199ENST00000436959EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-5UTRENST00000375208ENST00000436959EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-5UTRENST00000477853ENST00000436959EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000375199ENST00000534995EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000375199ENST00000537348EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000375199ENST00000545065EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000375208ENST00000534995EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000375208ENST00000537348EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000375208ENST00000545065EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000477853ENST00000534995EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000477853ENST00000537348EMC1chr1

19553807

-KNTC1chr12

123097657

+
5CDS-intronENST00000477853ENST00000545065EMC1chr1

19553807

-KNTC1chr12

123097657

+
In-frameENST00000375199ENST00000333479EMC1chr1

19553807

-KNTC1chr12

123097657

+
In-frameENST00000375199ENST00000450485EMC1chr1

19553807

-KNTC1chr12

123097657

+
In-frameENST00000375208ENST00000333479EMC1chr1

19553807

-KNTC1chr12

123097657

+
In-frameENST00000375208ENST00000450485EMC1chr1

19553807

-KNTC1chr12

123097657

+
In-frameENST00000477853ENST00000333479EMC1chr1

19553807

-KNTC1chr12

123097657

+
In-frameENST00000477853ENST00000450485EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-3CDSENST00000356068ENST00000333479EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-3CDSENST00000356068ENST00000450485EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-3CDSENST00000480380ENST00000333479EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-3CDSENST00000480380ENST00000450485EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-5UTRENST00000356068ENST00000436959EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-5UTRENST00000480380ENST00000436959EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-intronENST00000356068ENST00000534995EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-intronENST00000356068ENST00000537348EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-intronENST00000356068ENST00000545065EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-intronENST00000480380ENST00000534995EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-intronENST00000480380ENST00000537348EMC1chr1

19553807

-KNTC1chr12

123097657

+
intron-intronENST00000480380ENST00000545065EMC1chr1

19553807

-KNTC1chr12

123097657

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000477853EMC1chr119553807-ENST00000450485KNTC1chr12123097657+335722454332521069
ENST00000477853EMC1chr119553807-ENST00000333479KNTC1chr12123097657+342122454332521069
ENST00000375199EMC1chr119553807-ENST00000450485KNTC1chr12123097657+33112199032061068
ENST00000375199EMC1chr119553807-ENST00000333479KNTC1chr12123097657+33752199032061068
ENST00000375208EMC1chr119553807-ENST00000450485KNTC1chr12123097657+326121491331561047
ENST00000375208EMC1chr119553807-ENST00000333479KNTC1chr12123097657+332521491331561047

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000477853ENST00000450485EMC1chr119553807-KNTC1chr12123097657+0.0010244020.99897563
ENST00000477853ENST00000333479EMC1chr119553807-KNTC1chr12123097657+0.0008730420.999127
ENST00000375199ENST00000450485EMC1chr119553807-KNTC1chr12123097657+0.0010279760.99897206
ENST00000375199ENST00000333479EMC1chr119553807-KNTC1chr12123097657+0.0008734490.9991266
ENST00000375208ENST00000450485EMC1chr119553807-KNTC1chr12123097657+0.0007289560.9992711
ENST00000375208ENST00000333479EMC1chr119553807-KNTC1chr12123097657+0.0005897070.9994103

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Fusion Genomic Features for EMC1-KNTC1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EMC1chr119553806-KNTC1chr12123097658+2.04E-050.9999796
EMC1chr119553806-KNTC1chr12123097658+2.04E-050.9999796

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EMC1-KNTC1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:19553807/chr12:123097657)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EMC1

Q8N766

KNTC1

P50748

FUNCTION: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:30415835, PubMed:29809151, PubMed:29242231, PubMed:32459176, PubMed:32439656). Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:30415835, PubMed:29809151, PubMed:29242231). Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:30415835, PubMed:29809151). It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29809151, PubMed:29242231). By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835). By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable). {ECO:0000269|PubMed:29242231, ECO:0000269|PubMed:29809151, ECO:0000269|PubMed:30415835, ECO:0000269|PubMed:32439656, ECO:0000269|PubMed:32459176, ECO:0000305}.FUNCTION: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores (PubMed:11146660, PubMed:11590237, PubMed:15824131). Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. {ECO:0000269|PubMed:11146660, ECO:0000269|PubMed:11590237, ECO:0000269|PubMed:15824131, ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEMC1chr1:19553807chr12:123097657ENST00000375199-182323_962733993.0Topological domainLumenal
HgeneEMC1chr1:19553807chr12:123097657ENST00000375199-1823984_993733993.0Topological domainCytoplasmic
HgeneEMC1chr1:19553807chr12:123097657ENST00000375208-172223_962712972.0Topological domainLumenal
HgeneEMC1chr1:19553807chr12:123097657ENST00000375208-1722984_993712972.0Topological domainCytoplasmic
HgeneEMC1chr1:19553807chr12:123097657ENST00000477853-182323_962734994.0Topological domainLumenal
HgeneEMC1chr1:19553807chr12:123097657ENST00000477853-1823984_993734994.0Topological domainCytoplasmic
HgeneEMC1chr1:19553807chr12:123097657ENST00000375199-1823963_983733993.0TransmembraneHelical
HgeneEMC1chr1:19553807chr12:123097657ENST00000375208-1722963_983712972.0TransmembraneHelical
HgeneEMC1chr1:19553807chr12:123097657ENST00000477853-1823963_983734994.0TransmembraneHelical


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Fusion Gene Sequence for EMC1-KNTC1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26363_26363_1_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375199_KNTC1_chr12_123097657_ENST00000333479_length(transcript)=3375nt_BP=2199nt
ATGGCGGCTGAGTGGGCTTCTCGTTTCTGGCTTTGGGCTACGCTGCTGATTCCTGCGGCCGCGGTCTACGAAGACCAAGTGGGCAAGTTT
GATTGGAGACAGCAATATGTTGGGAAGGTCAAGTTTGCCTCCTTGGAATTTTCCCCTGGATCCAAGAAGTTGGTTGTAGCCACAGAGAAG
AATGTGATTGCAGCATTAAATTCCCGAACTGGGGAGATCTTGTGGCGCCATGTTGACAAGGGCACGGCAGAAGGGGCTGTGGATGCCATG
CTGCTGCACGGACAGGATGTGATCACTGTGTCCAATGGAGGCCGAATCATGCGTTCCTGGGAGACTAACATCGGGGGCCTGAACTGGGAG
ATAACCCTGGACAGTGGCAGTTTCCAGGCACTTGGGCTGGTTGGCCTGCAGGAGTCTGTAAGGTACATCGCAGTCCTGAAGAAGACTACA
CTTGCCCTCCATCACCTCTCCAGTGGGCACCTCAAGTGGGTGGAACATCTCCCAGAAAGTGACAGCATCCACTACCAGATGGTGTATTCT
TACGGCTCTGGGGTGGTGTGGGCCCTCGGAGTTGTTCCCTTCAGCCATGTGAACATTGTCAAGTTTAATGTGGAAGATGGAGAGATTGTT
CAGCAGGTTAGGGTTTCAACTCCGTGGCTGCAGCACCTGTCTGGAGCCTGTGGTGTGGTGGATGAGGCTGTCCTGGTGTGTCCTGACCCG
AGCTCACGTTCCCTCCAAACTTTGGCTCTGGAGACGGAATGGGAGTTGAGACAGATCCCACTGCAGTCTCTCGACTTAGAATTTGGAAGT
GGATTCCAACCCCGGGTCCTGCCTACCCAGCCCAACCCAGTGGACGCTTCCCGGGCCCAGTTCTTCCTGCACTTGTCCCCAAGCCACTAT
GCTCTGCTGCAGTACCATTATGGAACGCTGAGTTTGCTTAAAAACTTCCCACAGACTGCCCTAGTGAGCTTTGCCACCACTGGGGAGAAG
ACGGTGGCTGCAGTCATGGCCTGTCGGAATGAAGTGAAAAGTAGCAGTTCTGAAGATGGGTCAATGGGGAGCTTTTCGGAGAAGTCTAGT
TCAAAGGACTCTCTGGCTTGCTTCAATCAGACCTACACCATTAACCTATACCTCGTGGAGACAGGTCGGCGGCTGCTGGACACCACGATA
ACATTTAGCCTGGAACAGAGCGGCACTCGGCCTGAGCGGCTGTATATCCAGGTGTTCTTGAAGAAGGATGACTCAGTGGGCTACCGGGCT
TTGGTGCAGACAGAGGATCATCTGCTACTTTTCCTGCAGCAGTTGGCAGGGAAGGTGGTGCTGTGGAGCCGTGAGGAGTCCCTGGCAGAA
GTGGTGTGCCTAGAGATGGTGGACCTCCCCCTGACTGGGGCACAGGCCGAGCTGGAAGGAGAATTTGGCAAAAAGGCAGATGGCTTGCTG
GGGATGTTCCTGAAACGCCTCTCGTCTCAGCTTATCCTGCTGCAAGCATGGACTTCCCACCTCTGGAAAATGTTTTATGATGCTCGGAAG
CCCCGGAGTCAGATTAAGAATGAGATCAACATTGACACCCTGGCCAGAGATGAATTCAACCTCCAGAAGATGATGGTGATGGTAACAGCC
TCAGGCAAGCTTTTTGGCATTGAGAGCAGCTCTGGCACCATCCTGTGGAAACAGTATCTACCCAATGTCAAGCCAGACTCCTCCTTTAAA
CTGATGGTCCAGAGAACTACTGCTCATTTCCCCCATCCCCCACAGTGCACCCTGCTGGTGAAGGACAAGGAGTCGGGAATGAGTTCTCTG
TATGTCTTCAATCCCATTTTTGGGAAGTGGAGTCAGGTAGCTCCCCCAGTGCTGAAGCGCCCCATCTTGCAGTCCTTGCTTCTCCCAGTC
ATGGATCAAGACTACGCCAAGGTGTTGCTGTTGATAGATGATGAATACAAGGTCACAGCTTTTCCAGCCACTCGGAATGTCTTGCGACAG
CTACATGAGCTTGCCCCTTCCATCTTCTTCTATTTGGTGGATGCAGAGCAGGGACGGCTGTGTGGATATCGGCTTCGAAAGGATCTCACC
ACTGAGCTGAGTTGGGAGCTGACCATTCCCCCAGAAGTACAGCGGATCGTCAAGGTGAAGGGGAAACGCAGCAGTGAGCACGTTCATTCC
CAGGGCCGTGTGATGGGGGACCGCAGTGTGCTCTACAAGACATTAGGTATGCATCAGTTAACTTTTGCCCATAGAACTCGAGCTCTTCAG
TGTCTCTTCTATTTGGCTGACAAGGAAACTATAGAATCTCTCTTTAAAAAACCCATTGAAGAAGTGAAATCTTATTTGAGATGTATAACT
TTTCTGGCATCATTTGAGACTTTGAATATCCCCATCACATATGAATTATTTTGCAGCAGTCCTAAAGAAGGAATGATTAAGGGTCTGTGG
AAAAACCACAGCCACGAGTCCATGGCAGTAAGATTGGTGACTGAGCTGTGTTTAGAATACAAAATCTATGACCTGCAGCTTTGGAATGGA
CTCTTGCAAAAGCTTCTGGGCTTCAATATGATTCCTTATCTAAGGAAAGTTTTAAAAGCCATCTCCAGTATCCATTCTTTATGGCAGGTT
CCCTACTTCAGCAAAGCGTGGCAGCGTGTGATACAGATACCACTGCTTTCAGCCTCTTGTCCTTTAAGTCCTGATCAGCTGTCAGATTGT
TCTGAGAGTCTCATCGCTGTCCTCGAATGTCCAGTCTCAGGTGATCTTGACCTGATCGGAGTCGCCAGGCAGTATATCCAGTTAGAACTT
CCGGCTTTTGCATTAGCTTGTCTGATGCTCATGCCCCACTCAGAGAAAAGACACCAGCAAATTAAGAATTTTCTGGGTTCCTGTGACCCT
CAGGTTATTTTAAAGCAATTGGAAGAGCATATGAACACGGGCCAGCTAGCAGGATTTTCACATCAAATTAGAAGTCTGATTTTGAATAAT
ATCATCAATAAGAAGGAGTTTGGGATTTTGGCAAAGACCAAATACTTTCAAATGTTGAAGATGCATGCGATGAATACCAACAATATCACT
GAGCTAGTGAACTATTTGGCAAATGACTTAAGTTTAGATGAAGCTTCAGTCTTGATAACTGAATATTCAAAGCACTGCGGGAAACCTGTG
CCTCCAGACACTGCTCCCTGTGAAATTCTGAAGATGTTTCTTAGTGGATTATCGTAAATCACTGAACCTTTTTTTCAAGAAGGACAAGAA
TTTTGGAGTCTGCTATTAATGGACCATATTTATTACAGTTTTTAAATTGTACAATCTCTGTATTATAGCTATTTGTCTAACATTACCCCA

>26363_26363_1_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375199_KNTC1_chr12_123097657_ENST00000333479_length(amino acids)=1068AA_BP=733
MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEILWRHVDKGTAEGAVDAM
LLHGQDVITVSNGGRIMRSWETNIGGLNWEITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGS
GFQPRVLPTQPNPVDASRAQFFLHLSPSHYALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLAE
VVCLEMVDLPLTGAQAELEGEFGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA
SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPV
MDQDYAKVLLLIDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS
QGRVMGDRSVLYKTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGLW
KNHSHESMAVRLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSDC
SESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILNN

--------------------------------------------------------------
>26363_26363_2_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375199_KNTC1_chr12_123097657_ENST00000450485_length(transcript)=3311nt_BP=2199nt
ATGGCGGCTGAGTGGGCTTCTCGTTTCTGGCTTTGGGCTACGCTGCTGATTCCTGCGGCCGCGGTCTACGAAGACCAAGTGGGCAAGTTT
GATTGGAGACAGCAATATGTTGGGAAGGTCAAGTTTGCCTCCTTGGAATTTTCCCCTGGATCCAAGAAGTTGGTTGTAGCCACAGAGAAG
AATGTGATTGCAGCATTAAATTCCCGAACTGGGGAGATCTTGTGGCGCCATGTTGACAAGGGCACGGCAGAAGGGGCTGTGGATGCCATG
CTGCTGCACGGACAGGATGTGATCACTGTGTCCAATGGAGGCCGAATCATGCGTTCCTGGGAGACTAACATCGGGGGCCTGAACTGGGAG
ATAACCCTGGACAGTGGCAGTTTCCAGGCACTTGGGCTGGTTGGCCTGCAGGAGTCTGTAAGGTACATCGCAGTCCTGAAGAAGACTACA
CTTGCCCTCCATCACCTCTCCAGTGGGCACCTCAAGTGGGTGGAACATCTCCCAGAAAGTGACAGCATCCACTACCAGATGGTGTATTCT
TACGGCTCTGGGGTGGTGTGGGCCCTCGGAGTTGTTCCCTTCAGCCATGTGAACATTGTCAAGTTTAATGTGGAAGATGGAGAGATTGTT
CAGCAGGTTAGGGTTTCAACTCCGTGGCTGCAGCACCTGTCTGGAGCCTGTGGTGTGGTGGATGAGGCTGTCCTGGTGTGTCCTGACCCG
AGCTCACGTTCCCTCCAAACTTTGGCTCTGGAGACGGAATGGGAGTTGAGACAGATCCCACTGCAGTCTCTCGACTTAGAATTTGGAAGT
GGATTCCAACCCCGGGTCCTGCCTACCCAGCCCAACCCAGTGGACGCTTCCCGGGCCCAGTTCTTCCTGCACTTGTCCCCAAGCCACTAT
GCTCTGCTGCAGTACCATTATGGAACGCTGAGTTTGCTTAAAAACTTCCCACAGACTGCCCTAGTGAGCTTTGCCACCACTGGGGAGAAG
ACGGTGGCTGCAGTCATGGCCTGTCGGAATGAAGTGAAAAGTAGCAGTTCTGAAGATGGGTCAATGGGGAGCTTTTCGGAGAAGTCTAGT
TCAAAGGACTCTCTGGCTTGCTTCAATCAGACCTACACCATTAACCTATACCTCGTGGAGACAGGTCGGCGGCTGCTGGACACCACGATA
ACATTTAGCCTGGAACAGAGCGGCACTCGGCCTGAGCGGCTGTATATCCAGGTGTTCTTGAAGAAGGATGACTCAGTGGGCTACCGGGCT
TTGGTGCAGACAGAGGATCATCTGCTACTTTTCCTGCAGCAGTTGGCAGGGAAGGTGGTGCTGTGGAGCCGTGAGGAGTCCCTGGCAGAA
GTGGTGTGCCTAGAGATGGTGGACCTCCCCCTGACTGGGGCACAGGCCGAGCTGGAAGGAGAATTTGGCAAAAAGGCAGATGGCTTGCTG
GGGATGTTCCTGAAACGCCTCTCGTCTCAGCTTATCCTGCTGCAAGCATGGACTTCCCACCTCTGGAAAATGTTTTATGATGCTCGGAAG
CCCCGGAGTCAGATTAAGAATGAGATCAACATTGACACCCTGGCCAGAGATGAATTCAACCTCCAGAAGATGATGGTGATGGTAACAGCC
TCAGGCAAGCTTTTTGGCATTGAGAGCAGCTCTGGCACCATCCTGTGGAAACAGTATCTACCCAATGTCAAGCCAGACTCCTCCTTTAAA
CTGATGGTCCAGAGAACTACTGCTCATTTCCCCCATCCCCCACAGTGCACCCTGCTGGTGAAGGACAAGGAGTCGGGAATGAGTTCTCTG
TATGTCTTCAATCCCATTTTTGGGAAGTGGAGTCAGGTAGCTCCCCCAGTGCTGAAGCGCCCCATCTTGCAGTCCTTGCTTCTCCCAGTC
ATGGATCAAGACTACGCCAAGGTGTTGCTGTTGATAGATGATGAATACAAGGTCACAGCTTTTCCAGCCACTCGGAATGTCTTGCGACAG
CTACATGAGCTTGCCCCTTCCATCTTCTTCTATTTGGTGGATGCAGAGCAGGGACGGCTGTGTGGATATCGGCTTCGAAAGGATCTCACC
ACTGAGCTGAGTTGGGAGCTGACCATTCCCCCAGAAGTACAGCGGATCGTCAAGGTGAAGGGGAAACGCAGCAGTGAGCACGTTCATTCC
CAGGGCCGTGTGATGGGGGACCGCAGTGTGCTCTACAAGACATTAGGTATGCATCAGTTAACTTTTGCCCATAGAACTCGAGCTCTTCAG
TGTCTCTTCTATTTGGCTGACAAGGAAACTATAGAATCTCTCTTTAAAAAACCCATTGAAGAAGTGAAATCTTATTTGAGATGTATAACT
TTTCTGGCATCATTTGAGACTTTGAATATCCCCATCACATATGAATTATTTTGCAGCAGTCCTAAAGAAGGAATGATTAAGGGTCTGTGG
AAAAACCACAGCCACGAGTCCATGGCAGTAAGATTGGTGACTGAGCTGTGTTTAGAATACAAAATCTATGACCTGCAGCTTTGGAATGGA
CTCTTGCAAAAGCTTCTGGGCTTCAATATGATTCCTTATCTAAGGAAAGTTTTAAAAGCCATCTCCAGTATCCATTCTTTATGGCAGGTT
CCCTACTTCAGCAAAGCGTGGCAGCGTGTGATACAGATACCACTGCTTTCAGCCTCTTGTCCTTTAAGTCCTGATCAGCTGTCAGATTGT
TCTGAGAGTCTCATCGCTGTCCTCGAATGTCCAGTCTCAGGTGATCTTGACCTGATCGGAGTCGCCAGGCAGTATATCCAGTTAGAACTT
CCGGCTTTTGCATTAGCTTGTCTGATGCTCATGCCCCACTCAGAGAAAAGACACCAGCAAATTAAGAATTTTCTGGGTTCCTGTGACCCT
CAGGTTATTTTAAAGCAATTGGAAGAGCATATGAACACGGGCCAGCTAGCAGGATTTTCACATCAAATTAGAAGTCTGATTTTGAATAAT
ATCATCAATAAGAAGGAGTTTGGGATTTTGGCAAAGACCAAATACTTTCAAATGTTGAAGATGCATGCGATGAATACCAACAATATCACT
GAGCTAGTGAACTATTTGGCAAATGACTTAAGTTTAGATGAAGCTTCAGTCTTGATAACTGAATATTCAAAGCACTGCGGGAAACCTGTG
CCTCCAGACACTGCTCCCTGTGAAATTCTGAAGATGTTTCTTAGTGGATTATCGTAAATCACTGAACCTTTTTTTCAAGAAGGACAAGAA

>26363_26363_2_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375199_KNTC1_chr12_123097657_ENST00000450485_length(amino acids)=1068AA_BP=733
MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEILWRHVDKGTAEGAVDAM
LLHGQDVITVSNGGRIMRSWETNIGGLNWEITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGS
GFQPRVLPTQPNPVDASRAQFFLHLSPSHYALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLAE
VVCLEMVDLPLTGAQAELEGEFGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA
SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPV
MDQDYAKVLLLIDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS
QGRVMGDRSVLYKTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGLW
KNHSHESMAVRLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSDC
SESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILNN

--------------------------------------------------------------
>26363_26363_3_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375208_KNTC1_chr12_123097657_ENST00000333479_length(transcript)=3325nt_BP=2149nt
ATGCGCTCGCATCATGGCGGCTGAGTGGGCTTCTCGTTTCTGGCTTTGGGCTACGCTGCTGATTCCTGCGGCCGCGGTCTACGAAGACCA
AGTGGGCAAGTTTGATTGGAGACAGCAATATGTTGGGAAGGTCAAGTTTGCCTCCTTGGAATTTTCCCCTGGATCCAAGAAGTTGGTTGT
AGCCACAGAGAAGAATGTGATTGCAGCATTAAATTCCCGAACTGGGGAGATCTATGTGATCACTGTGTCCAATGGAGGCCGAATCATGCG
TTCCTGGGAGACTAACATCGGGGGCCTGAACTGGGAGATAACCCTGGACAGTGGCAGTTTCCAGGCACTTGGGCTGGTTGGCCTGCAGGA
GTCTGTAAGGTACATCGCAGTCCTGAAGAAGACTACACTTGCCCTCCATCACCTCTCCAGTGGGCACCTCAAGTGGGTGGAACATCTCCC
AGAAAGTGACAGCATCCACTACCAGATGGTGTATTCTTACGGCTCTGGGGTGGTGTGGGCCCTCGGAGTTGTTCCCTTCAGCCATGTGAA
CATTGTCAAGTTTAATGTGGAAGATGGAGAGATTGTTCAGCAGGTTAGGGTTTCAACTCCGTGGCTGCAGCACCTGTCTGGAGCCTGTGG
TGTGGTGGATGAGGCTGTCCTGGTGTGTCCTGACCCGAGCTCACGTTCCCTCCAAACTTTGGCTCTGGAGACGGAATGGGAGTTGAGACA
GATCCCACTGCAGTCTCTCGACTTAGAATTTGGAAGTGGATTCCAACCCCGGGTCCTGCCTACCCAGCCCAACCCAGTGGACGCTTCCCG
GGCCCAGTTCTTCCTGCACTTGTCCCCAAGCCACTATGCTCTGCTGCAGTACCATTATGGAACGCTGAGTTTGCTTAAAAACTTCCCACA
GACTGCCCTAGTGAGCTTTGCCACCACTGGGGAGAAGACGGTGGCTGCAGTCATGGCCTGTCGGAATGAAGTGCAGAAAAGTAGCAGTTC
TGAAGATGGGTCAATGGGGAGCTTTTCGGAGAAGTCTAGTTCAAAGGACTCTCTGGCTTGCTTCAATCAGACCTACACCATTAACCTATA
CCTCGTGGAGACAGGTCGGCGGCTGCTGGACACCACGATAACATTTAGCCTGGAACAGAGCGGCACTCGGCCTGAGCGGCTGTATATCCA
GGTGTTCTTGAAGAAGGATGACTCAGTGGGCTACCGGGCTTTGGTGCAGACAGAGGATCATCTGCTACTTTTCCTGCAGCAGTTGGCAGG
GAAGGTGGTGCTGTGGAGCCGTGAGGAGTCCCTGGCAGAAGTGGTGTGCCTAGAGATGGTGGACCTCCCCCTGACTGGGGCACAGGCCGA
GCTGGAAGGAGAATTTGGCAAAAAGGCAGATGGCTTGCTGGGGATGTTCCTGAAACGCCTCTCGTCTCAGCTTATCCTGCTGCAAGCATG
GACTTCCCACCTCTGGAAAATGTTTTATGATGCTCGGAAGCCCCGGAGTCAGATTAAGAATGAGATCAACATTGACACCCTGGCCAGAGA
TGAATTCAACCTCCAGAAGATGATGGTGATGGTAACAGCCTCAGGCAAGCTTTTTGGCATTGAGAGCAGCTCTGGCACCATCCTGTGGAA
ACAGTATCTACCCAATGTCAAGCCAGACTCCTCCTTTAAACTGATGGTCCAGAGAACTACTGCTCATTTCCCCCATCCCCCACAGTGCAC
CCTGCTGGTGAAGGACAAGGAGTCGGGAATGAGTTCTCTGTATGTCTTCAATCCCATTTTTGGGAAGTGGAGTCAGGTAGCTCCCCCAGT
GCTGAAGCGCCCCATCTTGCAGTCCTTGCTTCTCCCAGTCATGGATCAAGACTACGCCAAGGTGTTGCTGTTGATAGATGATGAATACAA
GGTCACAGCTTTTCCAGCCACTCGGAATGTCTTGCGACAGCTACATGAGCTTGCCCCTTCCATCTTCTTCTATTTGGTGGATGCAGAGCA
GGGACGGCTGTGTGGATATCGGCTTCGAAAGGATCTCACCACTGAGCTGAGTTGGGAGCTGACCATTCCCCCAGAAGTACAGCGGATCGT
CAAGGTGAAGGGGAAACGCAGCAGTGAGCACGTTCATTCCCAGGGCCGTGTGATGGGGGACCGCAGTGTGCTCTACAAGACATTAGGTAT
GCATCAGTTAACTTTTGCCCATAGAACTCGAGCTCTTCAGTGTCTCTTCTATTTGGCTGACAAGGAAACTATAGAATCTCTCTTTAAAAA
ACCCATTGAAGAAGTGAAATCTTATTTGAGATGTATAACTTTTCTGGCATCATTTGAGACTTTGAATATCCCCATCACATATGAATTATT
TTGCAGCAGTCCTAAAGAAGGAATGATTAAGGGTCTGTGGAAAAACCACAGCCACGAGTCCATGGCAGTAAGATTGGTGACTGAGCTGTG
TTTAGAATACAAAATCTATGACCTGCAGCTTTGGAATGGACTCTTGCAAAAGCTTCTGGGCTTCAATATGATTCCTTATCTAAGGAAAGT
TTTAAAAGCCATCTCCAGTATCCATTCTTTATGGCAGGTTCCCTACTTCAGCAAAGCGTGGCAGCGTGTGATACAGATACCACTGCTTTC
AGCCTCTTGTCCTTTAAGTCCTGATCAGCTGTCAGATTGTTCTGAGAGTCTCATCGCTGTCCTCGAATGTCCAGTCTCAGGTGATCTTGA
CCTGATCGGAGTCGCCAGGCAGTATATCCAGTTAGAACTTCCGGCTTTTGCATTAGCTTGTCTGATGCTCATGCCCCACTCAGAGAAAAG
ACACCAGCAAATTAAGAATTTTCTGGGTTCCTGTGACCCTCAGGTTATTTTAAAGCAATTGGAAGAGCATATGAACACGGGCCAGCTAGC
AGGATTTTCACATCAAATTAGAAGTCTGATTTTGAATAATATCATCAATAAGAAGGAGTTTGGGATTTTGGCAAAGACCAAATACTTTCA
AATGTTGAAGATGCATGCGATGAATACCAACAATATCACTGAGCTAGTGAACTATTTGGCAAATGACTTAAGTTTAGATGAAGCTTCAGT
CTTGATAACTGAATATTCAAAGCACTGCGGGAAACCTGTGCCTCCAGACACTGCTCCCTGTGAAATTCTGAAGATGTTTCTTAGTGGATT
ATCGTAAATCACTGAACCTTTTTTTCAAGAAGGACAAGAATTTTGGAGTCTGCTATTAATGGACCATATTTATTACAGTTTTTAAATTGT

>26363_26363_3_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375208_KNTC1_chr12_123097657_ENST00000333479_length(amino acids)=1047AA_BP=712
MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEIYVITVSNGGRIMRSWET
NIGGLNWEITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYSYGSGVVWALGVVPFSHVNIVKF
NVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFF
LHLSPSHYALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKSSSKDSLACFNQTYTINLYLVET
GRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGE
FGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTASGKLFGIESSSGTILWKQYLP
NVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAF
PATRNVLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHSQGRVMGDRSVLYKTLGMHQLT
FAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYK
IYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSDCSESLIAVLECPVSGDLDLIGV
ARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKM

--------------------------------------------------------------
>26363_26363_4_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375208_KNTC1_chr12_123097657_ENST00000450485_length(transcript)=3261nt_BP=2149nt
ATGCGCTCGCATCATGGCGGCTGAGTGGGCTTCTCGTTTCTGGCTTTGGGCTACGCTGCTGATTCCTGCGGCCGCGGTCTACGAAGACCA
AGTGGGCAAGTTTGATTGGAGACAGCAATATGTTGGGAAGGTCAAGTTTGCCTCCTTGGAATTTTCCCCTGGATCCAAGAAGTTGGTTGT
AGCCACAGAGAAGAATGTGATTGCAGCATTAAATTCCCGAACTGGGGAGATCTATGTGATCACTGTGTCCAATGGAGGCCGAATCATGCG
TTCCTGGGAGACTAACATCGGGGGCCTGAACTGGGAGATAACCCTGGACAGTGGCAGTTTCCAGGCACTTGGGCTGGTTGGCCTGCAGGA
GTCTGTAAGGTACATCGCAGTCCTGAAGAAGACTACACTTGCCCTCCATCACCTCTCCAGTGGGCACCTCAAGTGGGTGGAACATCTCCC
AGAAAGTGACAGCATCCACTACCAGATGGTGTATTCTTACGGCTCTGGGGTGGTGTGGGCCCTCGGAGTTGTTCCCTTCAGCCATGTGAA
CATTGTCAAGTTTAATGTGGAAGATGGAGAGATTGTTCAGCAGGTTAGGGTTTCAACTCCGTGGCTGCAGCACCTGTCTGGAGCCTGTGG
TGTGGTGGATGAGGCTGTCCTGGTGTGTCCTGACCCGAGCTCACGTTCCCTCCAAACTTTGGCTCTGGAGACGGAATGGGAGTTGAGACA
GATCCCACTGCAGTCTCTCGACTTAGAATTTGGAAGTGGATTCCAACCCCGGGTCCTGCCTACCCAGCCCAACCCAGTGGACGCTTCCCG
GGCCCAGTTCTTCCTGCACTTGTCCCCAAGCCACTATGCTCTGCTGCAGTACCATTATGGAACGCTGAGTTTGCTTAAAAACTTCCCACA
GACTGCCCTAGTGAGCTTTGCCACCACTGGGGAGAAGACGGTGGCTGCAGTCATGGCCTGTCGGAATGAAGTGCAGAAAAGTAGCAGTTC
TGAAGATGGGTCAATGGGGAGCTTTTCGGAGAAGTCTAGTTCAAAGGACTCTCTGGCTTGCTTCAATCAGACCTACACCATTAACCTATA
CCTCGTGGAGACAGGTCGGCGGCTGCTGGACACCACGATAACATTTAGCCTGGAACAGAGCGGCACTCGGCCTGAGCGGCTGTATATCCA
GGTGTTCTTGAAGAAGGATGACTCAGTGGGCTACCGGGCTTTGGTGCAGACAGAGGATCATCTGCTACTTTTCCTGCAGCAGTTGGCAGG
GAAGGTGGTGCTGTGGAGCCGTGAGGAGTCCCTGGCAGAAGTGGTGTGCCTAGAGATGGTGGACCTCCCCCTGACTGGGGCACAGGCCGA
GCTGGAAGGAGAATTTGGCAAAAAGGCAGATGGCTTGCTGGGGATGTTCCTGAAACGCCTCTCGTCTCAGCTTATCCTGCTGCAAGCATG
GACTTCCCACCTCTGGAAAATGTTTTATGATGCTCGGAAGCCCCGGAGTCAGATTAAGAATGAGATCAACATTGACACCCTGGCCAGAGA
TGAATTCAACCTCCAGAAGATGATGGTGATGGTAACAGCCTCAGGCAAGCTTTTTGGCATTGAGAGCAGCTCTGGCACCATCCTGTGGAA
ACAGTATCTACCCAATGTCAAGCCAGACTCCTCCTTTAAACTGATGGTCCAGAGAACTACTGCTCATTTCCCCCATCCCCCACAGTGCAC
CCTGCTGGTGAAGGACAAGGAGTCGGGAATGAGTTCTCTGTATGTCTTCAATCCCATTTTTGGGAAGTGGAGTCAGGTAGCTCCCCCAGT
GCTGAAGCGCCCCATCTTGCAGTCCTTGCTTCTCCCAGTCATGGATCAAGACTACGCCAAGGTGTTGCTGTTGATAGATGATGAATACAA
GGTCACAGCTTTTCCAGCCACTCGGAATGTCTTGCGACAGCTACATGAGCTTGCCCCTTCCATCTTCTTCTATTTGGTGGATGCAGAGCA
GGGACGGCTGTGTGGATATCGGCTTCGAAAGGATCTCACCACTGAGCTGAGTTGGGAGCTGACCATTCCCCCAGAAGTACAGCGGATCGT
CAAGGTGAAGGGGAAACGCAGCAGTGAGCACGTTCATTCCCAGGGCCGTGTGATGGGGGACCGCAGTGTGCTCTACAAGACATTAGGTAT
GCATCAGTTAACTTTTGCCCATAGAACTCGAGCTCTTCAGTGTCTCTTCTATTTGGCTGACAAGGAAACTATAGAATCTCTCTTTAAAAA
ACCCATTGAAGAAGTGAAATCTTATTTGAGATGTATAACTTTTCTGGCATCATTTGAGACTTTGAATATCCCCATCACATATGAATTATT
TTGCAGCAGTCCTAAAGAAGGAATGATTAAGGGTCTGTGGAAAAACCACAGCCACGAGTCCATGGCAGTAAGATTGGTGACTGAGCTGTG
TTTAGAATACAAAATCTATGACCTGCAGCTTTGGAATGGACTCTTGCAAAAGCTTCTGGGCTTCAATATGATTCCTTATCTAAGGAAAGT
TTTAAAAGCCATCTCCAGTATCCATTCTTTATGGCAGGTTCCCTACTTCAGCAAAGCGTGGCAGCGTGTGATACAGATACCACTGCTTTC
AGCCTCTTGTCCTTTAAGTCCTGATCAGCTGTCAGATTGTTCTGAGAGTCTCATCGCTGTCCTCGAATGTCCAGTCTCAGGTGATCTTGA
CCTGATCGGAGTCGCCAGGCAGTATATCCAGTTAGAACTTCCGGCTTTTGCATTAGCTTGTCTGATGCTCATGCCCCACTCAGAGAAAAG
ACACCAGCAAATTAAGAATTTTCTGGGTTCCTGTGACCCTCAGGTTATTTTAAAGCAATTGGAAGAGCATATGAACACGGGCCAGCTAGC
AGGATTTTCACATCAAATTAGAAGTCTGATTTTGAATAATATCATCAATAAGAAGGAGTTTGGGATTTTGGCAAAGACCAAATACTTTCA
AATGTTGAAGATGCATGCGATGAATACCAACAATATCACTGAGCTAGTGAACTATTTGGCAAATGACTTAAGTTTAGATGAAGCTTCAGT
CTTGATAACTGAATATTCAAAGCACTGCGGGAAACCTGTGCCTCCAGACACTGCTCCCTGTGAAATTCTGAAGATGTTTCTTAGTGGATT
ATCGTAAATCACTGAACCTTTTTTTCAAGAAGGACAAGAATTTTGGAGTCTGCTATTAATGGACCATATTTATTACAGTTTTTAAATTGT

>26363_26363_4_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000375208_KNTC1_chr12_123097657_ENST00000450485_length(amino acids)=1047AA_BP=712
MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEIYVITVSNGGRIMRSWET
NIGGLNWEITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYSYGSGVVWALGVVPFSHVNIVKF
NVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFF
LHLSPSHYALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKSSSKDSLACFNQTYTINLYLVET
GRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGE
FGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTASGKLFGIESSSGTILWKQYLP
NVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAF
PATRNVLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHSQGRVMGDRSVLYKTLGMHQLT
FAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYK
IYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSDCSESLIAVLECPVSGDLDLIGV
ARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKM

--------------------------------------------------------------
>26363_26363_5_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000477853_KNTC1_chr12_123097657_ENST00000333479_length(transcript)=3421nt_BP=2245nt
GGTGCATGCCGGGACGGCGGTGGGTGGTGCATGCGCTCGCATCATGGCGGCTGAGTGGGCTTCTCGTTTCTGGCTTTGGGCTACGCTGCT
GATTCCTGCGGCCGCGGTCTACGAAGACCAAGTGGGCAAGTTTGATTGGAGACAGCAATATGTTGGGAAGGTCAAGTTTGCCTCCTTGGA
ATTTTCCCCTGGATCCAAGAAGTTGGTTGTAGCCACAGAGAAGAATGTGATTGCAGCATTAAATTCCCGAACTGGGGAGATCTTGTGGCG
CCATGTTGACAAGGGCACGGCAGAAGGGGCTGTGGATGCCATGCTGCTGCACGGACAGGATGTGATCACTGTGTCCAATGGAGGCCGAAT
CATGCGTTCCTGGGAGACTAACATCGGGGGCCTGAACTGGGAGATAACCCTGGACAGTGGCAGTTTCCAGGCACTTGGGCTGGTTGGCCT
GCAGGAGTCTGTAAGGTACATCGCAGTCCTGAAGAAGACTACACTTGCCCTCCATCACCTCTCCAGTGGGCACCTCAAGTGGGTGGAACA
TCTCCCAGAAAGTGACAGCATCCACTACCAGATGGTGTATTCTTACGGCTCTGGGGTGGTGTGGGCCCTCGGAGTTGTTCCCTTCAGCCA
TGTGAACATTGTCAAGTTTAATGTGGAAGATGGAGAGATTGTTCAGCAGGTTAGGGTTTCAACTCCGTGGCTGCAGCACCTGTCTGGAGC
CTGTGGTGTGGTGGATGAGGCTGTCCTGGTGTGTCCTGACCCGAGCTCACGTTCCCTCCAAACTTTGGCTCTGGAGACGGAATGGGAGTT
GAGACAGATCCCACTGCAGTCTCTCGACTTAGAATTTGGAAGTGGATTCCAACCCCGGGTCCTGCCTACCCAGCCCAACCCAGTGGACGC
TTCCCGGGCCCAGTTCTTCCTGCACTTGTCCCCAAGCCACTATGCTCTGCTGCAGTACCATTATGGAACGCTGAGTTTGCTTAAAAACTT
CCCACAGACTGCCCTAGTGAGCTTTGCCACCACTGGGGAGAAGACGGTGGCTGCAGTCATGGCCTGTCGGAATGAAGTGCAGAAAAGTAG
CAGTTCTGAAGATGGGTCAATGGGGAGCTTTTCGGAGAAGTCTAGTTCAAAGGACTCTCTGGCTTGCTTCAATCAGACCTACACCATTAA
CCTATACCTCGTGGAGACAGGTCGGCGGCTGCTGGACACCACGATAACATTTAGCCTGGAACAGAGCGGCACTCGGCCTGAGCGGCTGTA
TATCCAGGTGTTCTTGAAGAAGGATGACTCAGTGGGCTACCGGGCTTTGGTGCAGACAGAGGATCATCTGCTACTTTTCCTGCAGCAGTT
GGCAGGGAAGGTGGTGCTGTGGAGCCGTGAGGAGTCCCTGGCAGAAGTGGTGTGCCTAGAGATGGTGGACCTCCCCCTGACTGGGGCACA
GGCCGAGCTGGAAGGAGAATTTGGCAAAAAGGCAGATGGCTTGCTGGGGATGTTCCTGAAACGCCTCTCGTCTCAGCTTATCCTGCTGCA
AGCATGGACTTCCCACCTCTGGAAAATGTTTTATGATGCTCGGAAGCCCCGGAGTCAGATTAAGAATGAGATCAACATTGACACCCTGGC
CAGAGATGAATTCAACCTCCAGAAGATGATGGTGATGGTAACAGCCTCAGGCAAGCTTTTTGGCATTGAGAGCAGCTCTGGCACCATCCT
GTGGAAACAGTATCTACCCAATGTCAAGCCAGACTCCTCCTTTAAACTGATGGTCCAGAGAACTACTGCTCATTTCCCCCATCCCCCACA
GTGCACCCTGCTGGTGAAGGACAAGGAGTCGGGAATGAGTTCTCTGTATGTCTTCAATCCCATTTTTGGGAAGTGGAGTCAGGTAGCTCC
CCCAGTGCTGAAGCGCCCCATCTTGCAGTCCTTGCTTCTCCCAGTCATGGATCAAGACTACGCCAAGGTGTTGCTGTTGATAGATGATGA
ATACAAGGTCACAGCTTTTCCAGCCACTCGGAATGTCTTGCGACAGCTACATGAGCTTGCCCCTTCCATCTTCTTCTATTTGGTGGATGC
AGAGCAGGGACGGCTGTGTGGATATCGGCTTCGAAAGGATCTCACCACTGAGCTGAGTTGGGAGCTGACCATTCCCCCAGAAGTACAGCG
GATCGTCAAGGTGAAGGGGAAACGCAGCAGTGAGCACGTTCATTCCCAGGGCCGTGTGATGGGGGACCGCAGTGTGCTCTACAAGACATT
AGGTATGCATCAGTTAACTTTTGCCCATAGAACTCGAGCTCTTCAGTGTCTCTTCTATTTGGCTGACAAGGAAACTATAGAATCTCTCTT
TAAAAAACCCATTGAAGAAGTGAAATCTTATTTGAGATGTATAACTTTTCTGGCATCATTTGAGACTTTGAATATCCCCATCACATATGA
ATTATTTTGCAGCAGTCCTAAAGAAGGAATGATTAAGGGTCTGTGGAAAAACCACAGCCACGAGTCCATGGCAGTAAGATTGGTGACTGA
GCTGTGTTTAGAATACAAAATCTATGACCTGCAGCTTTGGAATGGACTCTTGCAAAAGCTTCTGGGCTTCAATATGATTCCTTATCTAAG
GAAAGTTTTAAAAGCCATCTCCAGTATCCATTCTTTATGGCAGGTTCCCTACTTCAGCAAAGCGTGGCAGCGTGTGATACAGATACCACT
GCTTTCAGCCTCTTGTCCTTTAAGTCCTGATCAGCTGTCAGATTGTTCTGAGAGTCTCATCGCTGTCCTCGAATGTCCAGTCTCAGGTGA
TCTTGACCTGATCGGAGTCGCCAGGCAGTATATCCAGTTAGAACTTCCGGCTTTTGCATTAGCTTGTCTGATGCTCATGCCCCACTCAGA
GAAAAGACACCAGCAAATTAAGAATTTTCTGGGTTCCTGTGACCCTCAGGTTATTTTAAAGCAATTGGAAGAGCATATGAACACGGGCCA
GCTAGCAGGATTTTCACATCAAATTAGAAGTCTGATTTTGAATAATATCATCAATAAGAAGGAGTTTGGGATTTTGGCAAAGACCAAATA
CTTTCAAATGTTGAAGATGCATGCGATGAATACCAACAATATCACTGAGCTAGTGAACTATTTGGCAAATGACTTAAGTTTAGATGAAGC
TTCAGTCTTGATAACTGAATATTCAAAGCACTGCGGGAAACCTGTGCCTCCAGACACTGCTCCCTGTGAAATTCTGAAGATGTTTCTTAG
TGGATTATCGTAAATCACTGAACCTTTTTTTCAAGAAGGACAAGAATTTTGGAGTCTGCTATTAATGGACCATATTTATTACAGTTTTTA
AATTGTACAATCTCTGTATTATAGCTATTTGTCTAACATTACCCCACATGTAATAAATAAAACAATATGAGCATAATTGCCCCATAAAGA

>26363_26363_5_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000477853_KNTC1_chr12_123097657_ENST00000333479_length(amino acids)=1069AA_BP=734
MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEILWRHVDKGTAEGAVDAM
LLHGQDVITVSNGGRIMRSWETNIGGLNWEITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGS
GFQPRVLPTQPNPVDASRAQFFLHLSPSHYALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLA
EVVCLEMVDLPLTGAQAELEGEFGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLP
VMDQDYAKVLLLIDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
SQGRVMGDRSVLYKTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGL
WKNHSHESMAVRLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSD
CSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILN

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>26363_26363_6_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000477853_KNTC1_chr12_123097657_ENST00000450485_length(transcript)=3357nt_BP=2245nt
GGTGCATGCCGGGACGGCGGTGGGTGGTGCATGCGCTCGCATCATGGCGGCTGAGTGGGCTTCTCGTTTCTGGCTTTGGGCTACGCTGCT
GATTCCTGCGGCCGCGGTCTACGAAGACCAAGTGGGCAAGTTTGATTGGAGACAGCAATATGTTGGGAAGGTCAAGTTTGCCTCCTTGGA
ATTTTCCCCTGGATCCAAGAAGTTGGTTGTAGCCACAGAGAAGAATGTGATTGCAGCATTAAATTCCCGAACTGGGGAGATCTTGTGGCG
CCATGTTGACAAGGGCACGGCAGAAGGGGCTGTGGATGCCATGCTGCTGCACGGACAGGATGTGATCACTGTGTCCAATGGAGGCCGAAT
CATGCGTTCCTGGGAGACTAACATCGGGGGCCTGAACTGGGAGATAACCCTGGACAGTGGCAGTTTCCAGGCACTTGGGCTGGTTGGCCT
GCAGGAGTCTGTAAGGTACATCGCAGTCCTGAAGAAGACTACACTTGCCCTCCATCACCTCTCCAGTGGGCACCTCAAGTGGGTGGAACA
TCTCCCAGAAAGTGACAGCATCCACTACCAGATGGTGTATTCTTACGGCTCTGGGGTGGTGTGGGCCCTCGGAGTTGTTCCCTTCAGCCA
TGTGAACATTGTCAAGTTTAATGTGGAAGATGGAGAGATTGTTCAGCAGGTTAGGGTTTCAACTCCGTGGCTGCAGCACCTGTCTGGAGC
CTGTGGTGTGGTGGATGAGGCTGTCCTGGTGTGTCCTGACCCGAGCTCACGTTCCCTCCAAACTTTGGCTCTGGAGACGGAATGGGAGTT
GAGACAGATCCCACTGCAGTCTCTCGACTTAGAATTTGGAAGTGGATTCCAACCCCGGGTCCTGCCTACCCAGCCCAACCCAGTGGACGC
TTCCCGGGCCCAGTTCTTCCTGCACTTGTCCCCAAGCCACTATGCTCTGCTGCAGTACCATTATGGAACGCTGAGTTTGCTTAAAAACTT
CCCACAGACTGCCCTAGTGAGCTTTGCCACCACTGGGGAGAAGACGGTGGCTGCAGTCATGGCCTGTCGGAATGAAGTGCAGAAAAGTAG
CAGTTCTGAAGATGGGTCAATGGGGAGCTTTTCGGAGAAGTCTAGTTCAAAGGACTCTCTGGCTTGCTTCAATCAGACCTACACCATTAA
CCTATACCTCGTGGAGACAGGTCGGCGGCTGCTGGACACCACGATAACATTTAGCCTGGAACAGAGCGGCACTCGGCCTGAGCGGCTGTA
TATCCAGGTGTTCTTGAAGAAGGATGACTCAGTGGGCTACCGGGCTTTGGTGCAGACAGAGGATCATCTGCTACTTTTCCTGCAGCAGTT
GGCAGGGAAGGTGGTGCTGTGGAGCCGTGAGGAGTCCCTGGCAGAAGTGGTGTGCCTAGAGATGGTGGACCTCCCCCTGACTGGGGCACA
GGCCGAGCTGGAAGGAGAATTTGGCAAAAAGGCAGATGGCTTGCTGGGGATGTTCCTGAAACGCCTCTCGTCTCAGCTTATCCTGCTGCA
AGCATGGACTTCCCACCTCTGGAAAATGTTTTATGATGCTCGGAAGCCCCGGAGTCAGATTAAGAATGAGATCAACATTGACACCCTGGC
CAGAGATGAATTCAACCTCCAGAAGATGATGGTGATGGTAACAGCCTCAGGCAAGCTTTTTGGCATTGAGAGCAGCTCTGGCACCATCCT
GTGGAAACAGTATCTACCCAATGTCAAGCCAGACTCCTCCTTTAAACTGATGGTCCAGAGAACTACTGCTCATTTCCCCCATCCCCCACA
GTGCACCCTGCTGGTGAAGGACAAGGAGTCGGGAATGAGTTCTCTGTATGTCTTCAATCCCATTTTTGGGAAGTGGAGTCAGGTAGCTCC
CCCAGTGCTGAAGCGCCCCATCTTGCAGTCCTTGCTTCTCCCAGTCATGGATCAAGACTACGCCAAGGTGTTGCTGTTGATAGATGATGA
ATACAAGGTCACAGCTTTTCCAGCCACTCGGAATGTCTTGCGACAGCTACATGAGCTTGCCCCTTCCATCTTCTTCTATTTGGTGGATGC
AGAGCAGGGACGGCTGTGTGGATATCGGCTTCGAAAGGATCTCACCACTGAGCTGAGTTGGGAGCTGACCATTCCCCCAGAAGTACAGCG
GATCGTCAAGGTGAAGGGGAAACGCAGCAGTGAGCACGTTCATTCCCAGGGCCGTGTGATGGGGGACCGCAGTGTGCTCTACAAGACATT
AGGTATGCATCAGTTAACTTTTGCCCATAGAACTCGAGCTCTTCAGTGTCTCTTCTATTTGGCTGACAAGGAAACTATAGAATCTCTCTT
TAAAAAACCCATTGAAGAAGTGAAATCTTATTTGAGATGTATAACTTTTCTGGCATCATTTGAGACTTTGAATATCCCCATCACATATGA
ATTATTTTGCAGCAGTCCTAAAGAAGGAATGATTAAGGGTCTGTGGAAAAACCACAGCCACGAGTCCATGGCAGTAAGATTGGTGACTGA
GCTGTGTTTAGAATACAAAATCTATGACCTGCAGCTTTGGAATGGACTCTTGCAAAAGCTTCTGGGCTTCAATATGATTCCTTATCTAAG
GAAAGTTTTAAAAGCCATCTCCAGTATCCATTCTTTATGGCAGGTTCCCTACTTCAGCAAAGCGTGGCAGCGTGTGATACAGATACCACT
GCTTTCAGCCTCTTGTCCTTTAAGTCCTGATCAGCTGTCAGATTGTTCTGAGAGTCTCATCGCTGTCCTCGAATGTCCAGTCTCAGGTGA
TCTTGACCTGATCGGAGTCGCCAGGCAGTATATCCAGTTAGAACTTCCGGCTTTTGCATTAGCTTGTCTGATGCTCATGCCCCACTCAGA
GAAAAGACACCAGCAAATTAAGAATTTTCTGGGTTCCTGTGACCCTCAGGTTATTTTAAAGCAATTGGAAGAGCATATGAACACGGGCCA
GCTAGCAGGATTTTCACATCAAATTAGAAGTCTGATTTTGAATAATATCATCAATAAGAAGGAGTTTGGGATTTTGGCAAAGACCAAATA
CTTTCAAATGTTGAAGATGCATGCGATGAATACCAACAATATCACTGAGCTAGTGAACTATTTGGCAAATGACTTAAGTTTAGATGAAGC
TTCAGTCTTGATAACTGAATATTCAAAGCACTGCGGGAAACCTGTGCCTCCAGACACTGCTCCCTGTGAAATTCTGAAGATGTTTCTTAG
TGGATTATCGTAAATCACTGAACCTTTTTTTCAAGAAGGACAAGAATTTTGGAGTCTGCTATTAATGGACCATATTTATTACAGTTTTTA

>26363_26363_6_EMC1-KNTC1_EMC1_chr1_19553807_ENST00000477853_KNTC1_chr12_123097657_ENST00000450485_length(amino acids)=1069AA_BP=734
MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEILWRHVDKGTAEGAVDAM
LLHGQDVITVSNGGRIMRSWETNIGGLNWEITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGS
GFQPRVLPTQPNPVDASRAQFFLHLSPSHYALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLA
EVVCLEMVDLPLTGAQAELEGEFGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLP
VMDQDYAKVLLLIDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
SQGRVMGDRSVLYKTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCITFLASFETLNIPITYELFCSSPKEGMIKGL
WKNHSHESMAVRLVTELCLEYKIYDLQLWNGLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSD
CSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCDPQVILKQLEEHMNTGQLAGFSHQIRSLILN

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Fusion Gene PPI Analysis for EMC1-KNTC1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EMC1-KNTC1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EMC1-KNTC1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource