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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EML4-EPHA3 (FusionGDB2 ID:26460)

Fusion Gene Summary for EML4-EPHA3

check button Fusion gene summary
Fusion gene informationFusion gene name: EML4-EPHA3
Fusion gene ID: 26460
HgeneTgene
Gene symbol

EML4

EPHA3

Gene ID

27436

2042

Gene nameEMAP like 4EPH receptor A3
SynonymsC2orf2|ELP120|EMAP-4|EMAPL4|ROPP120EK4|ETK|ETK1|HEK|HEK4|TYRO4
Cytomap

2p21

3p11.1

Type of geneprotein-codingprotein-coding
Descriptionechinoderm microtubule-associated protein-like 4echinoderm microtubule associated protein like 4restrictedly overexpressed proliferation-associated proteinropp 120ephrin type-A receptor 3EPH-like kinase 4TYRO4 protein tyrosine kinaseeph-like tyrosine kinase 1human embryo kinase 1testicular tissue protein Li 64tyrosine-protein kinase receptor ETK1
Modification date2020031320200313
UniProtAcc

Q9HC35

P29320

Ensembl transtripts involved in fusion geneENST00000318522, ENST00000401738, 
ENST00000402711, ENST00000453191, 
ENST00000482660, 		ENST00000452448, 
ENST00000494014, ENST00000336596, 
Fusion gene scores* DoF score22 X 32 X 18=126728 X 9 X 5=360
# samples 439
** MAII scorelog2(43/12672*10)=-4.88116377049015
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/360*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EML4 [Title/Abstract] AND EPHA3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEML4(42528532)-EPHA3(89498375), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneEPHA3

GO:0018108

peptidyl-tyrosine phosphorylation

11877430

TgeneEPHA3

GO:0032956

regulation of actin cytoskeleton organization

11870224

TgeneEPHA3

GO:0043087

regulation of GTPase activity

11870224

TgeneEPHA3

GO:0045806

negative regulation of endocytosis

11877430

TgeneEPHA3

GO:0048013

ephrin receptor signaling pathway

11870224

TgeneEPHA3

GO:0051893

regulation of focal adhesion assembly

11870224

TgeneEPHA3

GO:0070507

regulation of microtubule cytoskeleton organization

11870224

TgeneEPHA3

GO:1903078

positive regulation of protein localization to plasma membrane

11877430


check buttonFusion gene breakpoints across EML4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EPHA3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-IG-A8O2-01AEML4chr2

42528532

+EPHA3chr3

89498375

+
ChimerDB4ESCATCGA-IG-A8O2EML4chr2

42528532

+EPHA3chr3

89498374

+
ChimerDB4ESCATCGA-IG-A8O2EML4chr2

42528532

+EPHA3chr3

89498375

+


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Fusion Gene ORF analysis for EML4-EPHA3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000318522ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498375

+
5CDS-intronENST00000318522ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498374

+
5CDS-intronENST00000318522ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498375

+
5CDS-intronENST00000318522ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498374

+
5CDS-intronENST00000401738ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498375

+
5CDS-intronENST00000401738ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498374

+
5CDS-intronENST00000401738ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498375

+
5CDS-intronENST00000401738ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498374

+
5CDS-intronENST00000402711ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498375

+
5CDS-intronENST00000402711ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498374

+
5CDS-intronENST00000402711ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498375

+
5CDS-intronENST00000402711ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498374

+
5UTR-3CDSENST00000453191ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498375

+
5UTR-3CDSENST00000453191ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498374

+
5UTR-intronENST00000453191ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498375

+
5UTR-intronENST00000453191ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498374

+
5UTR-intronENST00000453191ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498375

+
5UTR-intronENST00000453191ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498374

+
In-frameENST00000318522ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498375

+
In-frameENST00000318522ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498374

+
In-frameENST00000401738ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498375

+
In-frameENST00000401738ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498374

+
In-frameENST00000402711ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498375

+
In-frameENST00000402711ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498374

+
intron-3CDSENST00000482660ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498375

+
intron-3CDSENST00000482660ENST00000336596EML4chr2

42528532

+EPHA3chr3

89498374

+
intron-intronENST00000482660ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498375

+
intron-intronENST00000482660ENST00000452448EML4chr2

42528532

+EPHA3chr3

89498374

+
intron-intronENST00000482660ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498375

+
intron-intronENST00000482660ENST00000494014EML4chr2

42528532

+EPHA3chr3

89498374

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000318522EML4chr242528532+ENST00000336596EPHA3chr389498375+514119032622508748
ENST00000402711EML4chr242528532+ENST00000336596EPHA3chr389498375+496417262592331690
ENST00000401738EML4chr242528532+ENST00000336596EPHA3chr389498375+506318251512430759
ENST00000318522EML4chr242528532+ENST00000336596EPHA3chr389498374+514119032622508748
ENST00000402711EML4chr242528532+ENST00000336596EPHA3chr389498374+496417262592331690
ENST00000401738EML4chr242528532+ENST00000336596EPHA3chr389498374+506318251512430759

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000318522ENST00000336596EML4chr242528532+EPHA3chr389498375+0.000163080.9998369
ENST00000402711ENST00000336596EML4chr242528532+EPHA3chr389498375+0.0001484150.9998516
ENST00000401738ENST00000336596EML4chr242528532+EPHA3chr389498375+0.0001815110.9998185
ENST00000318522ENST00000336596EML4chr242528532+EPHA3chr389498374+0.000163080.9998369
ENST00000402711ENST00000336596EML4chr242528532+EPHA3chr389498374+0.0001484150.9998516
ENST00000401738ENST00000336596EML4chr242528532+EPHA3chr389498374+0.0001815110.9998185

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Fusion Genomic Features for EML4-EPHA3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EML4chr242528532+EPHA3chr389498374+0.0006709010.9993291
EML4chr242528532+EPHA3chr389498374+0.0006709010.9993291
EML4chr242528532+EPHA3chr389498374+0.0006709010.9993291
EML4chr242528532+EPHA3chr389498374+0.0006709010.9993291

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EML4-EPHA3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:42528532/chr3:89498375)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EML4

Q9HC35

EPHA3

P29320

FUNCTION: Essential for the formation and stability of microtubules (MTs) (PubMed:16890222, PubMed:31409757). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs (PubMed:25789526). Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression (PubMed:25789526). {ECO:0000269|PubMed:16890222, ECO:0000269|PubMed:25789526, ECO:0000269|PubMed:31409757}.FUNCTION: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development. {ECO:0000269|PubMed:11870224}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+14231_249547982.0RegionMicrotubule-binding
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+13221_249489924.0RegionMicrotubule-binding
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+14231_249547982.0RegionMicrotubule-binding
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+13221_249489924.0RegionMicrotubule-binding
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423259_297547982.0RepeatNote=WD 1
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423301_348547982.0RepeatNote=WD 2
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423356_396547982.0RepeatNote=WD 3
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423403_438547982.0RepeatNote=WD 4
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423445_484547982.0RepeatNote=WD 5
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423500_538547982.0RepeatNote=WD 6
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322259_297489924.0RepeatNote=WD 1
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322301_348489924.0RepeatNote=WD 2
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322356_396489924.0RepeatNote=WD 3
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322403_438489924.0RepeatNote=WD 4
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322445_484489924.0RepeatNote=WD 5
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423259_297547982.0RepeatNote=WD 1
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423301_348547982.0RepeatNote=WD 2
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423356_396547982.0RepeatNote=WD 3
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423403_438547982.0RepeatNote=WD 4
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423445_484547982.0RepeatNote=WD 5
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423500_538547982.0RepeatNote=WD 6
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322259_297489924.0RepeatNote=WD 1
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322301_348489924.0RepeatNote=WD 2
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322356_396489924.0RepeatNote=WD 3
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322403_438489924.0RepeatNote=WD 4
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322445_484489924.0RepeatNote=WD 5
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807189_3220540.0Compositional biasNote=Cys-rich
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807189_3220540.0Compositional biasNote=Cys-rich
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217911_975782984.0DomainSAM
TgeneEPHA3chr2:42528532chr3:89498374ENST000004524480729_2070540.0DomainEph LBD
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807325_4350540.0DomainFibronectin type-III 1
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807436_5310540.0DomainFibronectin type-III 2
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807621_8820540.0DomainProtein kinase
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807911_9750540.0DomainSAM
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217911_975782984.0DomainSAM
TgeneEPHA3chr2:42528532chr3:89498375ENST000004524480729_2070540.0DomainEph LBD
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807325_4350540.0DomainFibronectin type-III 1
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807436_5310540.0DomainFibronectin type-III 2
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807621_8820540.0DomainProtein kinase
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807911_9750540.0DomainSAM
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217981_983782984.0MotifPDZ-binding
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807981_9830540.0MotifPDZ-binding
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217981_983782984.0MotifPDZ-binding
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807981_9830540.0MotifPDZ-binding
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807628_6330540.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807700_7060540.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807750_7510540.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807628_6330540.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807700_7060540.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807750_7510540.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498374ENST000004524480721_5410540.0Topological domainExtracellular
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807566_9830540.0Topological domainCytoplasmic
TgeneEPHA3chr2:42528532chr3:89498375ENST000004524480721_5410540.0Topological domainExtracellular
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807566_9830540.0Topological domainCytoplasmic
TgeneEPHA3chr2:42528532chr3:89498374ENST0000045244807542_5650540.0TransmembraneHelical
TgeneEPHA3chr2:42528532chr3:89498375ENST0000045244807542_5650540.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423543_579547982.0RepeatNote=WD 7
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423582_621547982.0RepeatNote=WD 8
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423625_662547982.0RepeatNote=WD 9
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423668_704547982.0RepeatNote=WD 10
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423711_750547982.0RepeatNote=WD 11
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423760_818547982.0RepeatNote=WD 12
HgeneEML4chr2:42528532chr3:89498374ENST00000318522+1423825_864547982.0RepeatNote=WD 13
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322500_538489924.0RepeatNote=WD 6
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322543_579489924.0RepeatNote=WD 7
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322582_621489924.0RepeatNote=WD 8
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322625_662489924.0RepeatNote=WD 9
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322668_704489924.0RepeatNote=WD 10
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322711_750489924.0RepeatNote=WD 11
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322760_818489924.0RepeatNote=WD 12
HgeneEML4chr2:42528532chr3:89498374ENST00000402711+1322825_864489924.0RepeatNote=WD 13
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423543_579547982.0RepeatNote=WD 7
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423582_621547982.0RepeatNote=WD 8
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423625_662547982.0RepeatNote=WD 9
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423668_704547982.0RepeatNote=WD 10
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423711_750547982.0RepeatNote=WD 11
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423760_818547982.0RepeatNote=WD 12
HgeneEML4chr2:42528532chr3:89498375ENST00000318522+1423825_864547982.0RepeatNote=WD 13
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322500_538489924.0RepeatNote=WD 6
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322543_579489924.0RepeatNote=WD 7
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322582_621489924.0RepeatNote=WD 8
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322625_662489924.0RepeatNote=WD 9
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322668_704489924.0RepeatNote=WD 10
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322711_750489924.0RepeatNote=WD 11
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322760_818489924.0RepeatNote=WD 12
HgeneEML4chr2:42528532chr3:89498375ENST00000402711+1322825_864489924.0RepeatNote=WD 13
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217189_322782984.0Compositional biasNote=Cys-rich
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217189_322782984.0Compositional biasNote=Cys-rich
TgeneEPHA3chr2:42528532chr3:89498374ENST00000336596121729_207782984.0DomainEph LBD
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217325_435782984.0DomainFibronectin type-III 1
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217436_531782984.0DomainFibronectin type-III 2
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217621_882782984.0DomainProtein kinase
TgeneEPHA3chr2:42528532chr3:89498375ENST00000336596121729_207782984.0DomainEph LBD
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217325_435782984.0DomainFibronectin type-III 1
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217436_531782984.0DomainFibronectin type-III 2
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217621_882782984.0DomainProtein kinase
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217628_633782984.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217700_706782984.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217750_751782984.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217628_633782984.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217700_706782984.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217750_751782984.0Nucleotide bindingNote=ATP
TgeneEPHA3chr2:42528532chr3:89498374ENST00000336596121721_541782984.0Topological domainExtracellular
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217566_983782984.0Topological domainCytoplasmic
TgeneEPHA3chr2:42528532chr3:89498375ENST00000336596121721_541782984.0Topological domainExtracellular
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217566_983782984.0Topological domainCytoplasmic
TgeneEPHA3chr2:42528532chr3:89498374ENST000003365961217542_565782984.0TransmembraneHelical
TgeneEPHA3chr2:42528532chr3:89498375ENST000003365961217542_565782984.0TransmembraneHelical


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Fusion Gene Sequence for EML4-EPHA3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26460_26460_1_EML4-EPHA3_EML4_chr2_42528532_ENST00000318522_EPHA3_chr3_89498374_ENST00000336596_length(transcript)=5141nt_BP=1903nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGA
TGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAG
AGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCG
ACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGA
TAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGA
GCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTACTGT
ATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAA
TACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATA
TGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAG
CAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTT
CACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
AAGAGAAATAGAGGGAGGGAAGATCCCAATCAGGTGGACATCACCAGAAGCTATAGCCTACCGCAAGTTCACGTCAGCCAGCGATGTATG
GAGTTATGGGATTGTTCTCTGGGAGGTGATGTCTTATGGAGAGAGACCATACTGGGAGATGTCCAATCAGGATGTAATTAAAGCTGTAGA
TGAGGGCTATCGACTGCCACCCCCCATGGACTGCCCAGCTGCCTTGTATCAGCTGATGCTGGACTGCTGGCAGAAAGACAGGAACAACAG
ACCCAAGTTTGAGCAGATTGTTAGTATTCTGGACAAGCTTATCCGGAATCCCGGCAGCCTGAAGATCATCACCAGTGCAGCCGCAAGGCC
ATCAAACCTTCTTCTGGACCAAAGCAATGTGGATATCACTACCTTCCGCACAACAGGTGACTGGCTTAATGGTGTCTGGACAGCACACTG
CAAGGAAATCTTCACGGGTGTGGAGTACAGTTCTTGTGACACAATAGCCAAGATTTCCACAGATGACATGAAAAAGGTTGGTGTCACCGT
GGTTGGGCCACAGAAGAAGATCATCAGTAGCATTAAAGCTCTAGAAACGCAATCAAAGAATGGCCCAGTTCCCGTGTAAAGCACGGGACG
GAAGTGCTTCTGGACGGAAGTGGTGGCTGTGGAAGGCGTAGCATCATCCTGCAGACAGACAATAATTCTGGAGATACTGGTGGAAGTTCC
AAGTCCAATAAGACACTCAAATATGAGTACAAATGCCTTAAAATGGAATTGAAAAACTCTTTATTTTCCCCTATCATTTATTGGATGGGT
GGGTGGGGTATTTTTTTGTAATTGCTTTTTTAAATATTAGTTAATGGATTAAATTTAATTCTTCAGCGTAAAATGGTGAAGAACTAGCAT
ATAGCCATTGATCATAAACTGACTATCATAAAATCAAAACAAGTGAAATAACAAAATGGACATGGTGGCTTTGTTTAGGTAGAGCCACAA
AAGAAAAGACTTGTAATATTTTTATATACAGAGGAAATCTGTAACAGGTATTTTGTTTCTTTTAAAGCAAGCAACACAGAGGAATTTATA
CCTCAAACTATCTGGCCATATTTACTACCTTATCACTGCATTATTCTCTTTTATCTGTTTAAAGCATATAGAGATGAAGTTTGTAGTTGT
TTTAAGTACTACACATTTTTAAATTGTTAGCTTCCTTAAGTATATCATGTAAAGAAATGTCTTAATTTTTGAAAAAAGTACATATTTATT
TTCTTTTGAATTGTTTTTATTGTTTTCTATTTATGCCTTGATGATTTAATATGGATTTGTTACAGCCAAGTGCCAAATGCTCTCTCAAAT
TGTCAGCAATTTAACTAGACACAGATAATAATGGGTTTCTTTCAGATTTTTTGAACCATCCACTTACATATATTTTTAAAAAATGAAATC
CTTTTCCTGTTCATACACTAACCAAATCTCTCAAATCTGTTATCCCAATCATTGTTGCCTCTCCGTTTATTATAAACTGTATGCTCACAA
CTTAGTGTAATATACCAGCTTGTATGCAATGGATTTTCAACCAGATAACATACCTTTCCTGCTCTGGTGCTTAGAGACTATCAACTCCCT
CCTTTAGTGAAGGAGCCGTGTTAGAGCTTCCGAGAATAGCTCCACTGGAGAGAAGTGGAATCCTATATAGAATGCTGCACTAATTGACAA
CACAGCCTATAGGCCAATGCATGAGTAAAAAAAAAAACAATTACTGGCTCACTGGCTTTGAAAAGTCACTTACTATTGTTGCTGAAACTT
GCTGAGCTGTTTATAGAGAATGATGATAACAGAACTTTTCCTCTGTATCACTGGTGTTTAGGTGAATTAATTAAACATTGTGATCATTAG
TACCAGGTATTATTATCTTTAAGAGTCTTCCACTTCAATGCACATGGTGCAGTTTTGGTGTGTAACTTAGAAGGATTGAACTTCTTTGAA
TTTACTGGACATAACATTTTCAGAATAGTTGGTCATCTAGCAACCGCCTCAAAATGTGTAAGCAGGAGAGAAATTTCTCATCACAGGGAT
TTAGACTTACTATTACATAAAGGCTAACTATGAGCTTGCTCATTAATTTTGAAAAGATGTACCTGGTGGATATCTAGCTAGTAATATATT
CTGAAGCAACATTTTAGCTCTATTGATACTCTTTCTAATGCTGATATGATCTTGAGTATAAGAAATGCATATGTCACTAGAATGGATAAA
ATAATGCTGCAAACTTAATGTTCTTATGCAAAATGGAACGCTAATGAAACACAGCTTACAATCGCAAATCAAAACTCACAAGTGCTCATC
TGTTGTAGATTTAGTGTAATAAGACTTAGATTGTGCTCCTTCGGATATGATTGTTTCTCAAATCTTGGCAATATTCCTTAGTCAAATCAG
GCTACTAGAATTCTGTATTGGATATATAAGAGCATGAAATTTTTAAAAATACACTTGTGATTATAAAATTAATCACAAATTTCACTTATA
CCTGCTATCAGCAGCTAGAAAACATTTTTTTTTTAAATCAAGTATTTTGTGTTTGGAATGTTAGAATGAGATCTGAATGTGGTTTCAATC
TAATTTTTTCCCAGACTACTATTTTCTTTTTTAGGTACTATTCTGAGCATACTCAACAAAACCCATGCATTTCATAAACTAATAGAAGTT
GAGGATTGTTGAATCTATTTCACTTATTTTGGCTGTGGTTTCCATCTGAAAGTAGAGGTTGTATACACCATATACTGTTCTTCATTTTAT
TAATATTTTTCTCCTTGACCTCTCATAAATTTACTTTACACAATTCTTACCCTGTACATATGTAAACATAAGTGTACGATTCTTAACCAT
GGAGTAGAGGTACTAGAATGCTTACGGCCATCTCTTTGTACAGGAACTGCATTGACTTTCAGTAAACATAAAGCCACAACTCCTACATGA
TGTTATGTACCATATGATCTGTTTTGTATCTTAAATTTGATTTACATATATTATTTATTTCTGGTAACTCACTCAGTTTATGCTGTGCTA
AATATCAATCAAGCCATGTATAAATGTGATATGATTGGCAATATGTGTTTACTTTAAACTTGTCTTTTCAAAATATTACTCAGTTTATGT
TGTACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTGTAGTGGAAACATTTATATTTTTATAATAAACATAATGAAAATATTTTTT

>26460_26460_1_EML4-EPHA3_EML4_chr2_42528532_ENST00000318522_EPHA3_chr3_89498374_ENST00000336596_length(amino acids)=748AA_BP=547
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKLEWAYGYRGK
DCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLG
TFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGIF
GKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDL
NPEREIEGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDR
NNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVG

--------------------------------------------------------------
>26460_26460_2_EML4-EPHA3_EML4_chr2_42528532_ENST00000318522_EPHA3_chr3_89498375_ENST00000336596_length(transcript)=5141nt_BP=1903nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGA
TGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAG
AGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCG
ACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGA
TAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGA
GCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTACTGT
ATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAA
TACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATA
TGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAG
CAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTT
CACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
AAGAGAAATAGAGGGAGGGAAGATCCCAATCAGGTGGACATCACCAGAAGCTATAGCCTACCGCAAGTTCACGTCAGCCAGCGATGTATG
GAGTTATGGGATTGTTCTCTGGGAGGTGATGTCTTATGGAGAGAGACCATACTGGGAGATGTCCAATCAGGATGTAATTAAAGCTGTAGA
TGAGGGCTATCGACTGCCACCCCCCATGGACTGCCCAGCTGCCTTGTATCAGCTGATGCTGGACTGCTGGCAGAAAGACAGGAACAACAG
ACCCAAGTTTGAGCAGATTGTTAGTATTCTGGACAAGCTTATCCGGAATCCCGGCAGCCTGAAGATCATCACCAGTGCAGCCGCAAGGCC
ATCAAACCTTCTTCTGGACCAAAGCAATGTGGATATCACTACCTTCCGCACAACAGGTGACTGGCTTAATGGTGTCTGGACAGCACACTG
CAAGGAAATCTTCACGGGTGTGGAGTACAGTTCTTGTGACACAATAGCCAAGATTTCCACAGATGACATGAAAAAGGTTGGTGTCACCGT
GGTTGGGCCACAGAAGAAGATCATCAGTAGCATTAAAGCTCTAGAAACGCAATCAAAGAATGGCCCAGTTCCCGTGTAAAGCACGGGACG
GAAGTGCTTCTGGACGGAAGTGGTGGCTGTGGAAGGCGTAGCATCATCCTGCAGACAGACAATAATTCTGGAGATACTGGTGGAAGTTCC
AAGTCCAATAAGACACTCAAATATGAGTACAAATGCCTTAAAATGGAATTGAAAAACTCTTTATTTTCCCCTATCATTTATTGGATGGGT
GGGTGGGGTATTTTTTTGTAATTGCTTTTTTAAATATTAGTTAATGGATTAAATTTAATTCTTCAGCGTAAAATGGTGAAGAACTAGCAT
ATAGCCATTGATCATAAACTGACTATCATAAAATCAAAACAAGTGAAATAACAAAATGGACATGGTGGCTTTGTTTAGGTAGAGCCACAA
AAGAAAAGACTTGTAATATTTTTATATACAGAGGAAATCTGTAACAGGTATTTTGTTTCTTTTAAAGCAAGCAACACAGAGGAATTTATA
CCTCAAACTATCTGGCCATATTTACTACCTTATCACTGCATTATTCTCTTTTATCTGTTTAAAGCATATAGAGATGAAGTTTGTAGTTGT
TTTAAGTACTACACATTTTTAAATTGTTAGCTTCCTTAAGTATATCATGTAAAGAAATGTCTTAATTTTTGAAAAAAGTACATATTTATT
TTCTTTTGAATTGTTTTTATTGTTTTCTATTTATGCCTTGATGATTTAATATGGATTTGTTACAGCCAAGTGCCAAATGCTCTCTCAAAT
TGTCAGCAATTTAACTAGACACAGATAATAATGGGTTTCTTTCAGATTTTTTGAACCATCCACTTACATATATTTTTAAAAAATGAAATC
CTTTTCCTGTTCATACACTAACCAAATCTCTCAAATCTGTTATCCCAATCATTGTTGCCTCTCCGTTTATTATAAACTGTATGCTCACAA
CTTAGTGTAATATACCAGCTTGTATGCAATGGATTTTCAACCAGATAACATACCTTTCCTGCTCTGGTGCTTAGAGACTATCAACTCCCT
CCTTTAGTGAAGGAGCCGTGTTAGAGCTTCCGAGAATAGCTCCACTGGAGAGAAGTGGAATCCTATATAGAATGCTGCACTAATTGACAA
CACAGCCTATAGGCCAATGCATGAGTAAAAAAAAAAACAATTACTGGCTCACTGGCTTTGAAAAGTCACTTACTATTGTTGCTGAAACTT
GCTGAGCTGTTTATAGAGAATGATGATAACAGAACTTTTCCTCTGTATCACTGGTGTTTAGGTGAATTAATTAAACATTGTGATCATTAG
TACCAGGTATTATTATCTTTAAGAGTCTTCCACTTCAATGCACATGGTGCAGTTTTGGTGTGTAACTTAGAAGGATTGAACTTCTTTGAA
TTTACTGGACATAACATTTTCAGAATAGTTGGTCATCTAGCAACCGCCTCAAAATGTGTAAGCAGGAGAGAAATTTCTCATCACAGGGAT
TTAGACTTACTATTACATAAAGGCTAACTATGAGCTTGCTCATTAATTTTGAAAAGATGTACCTGGTGGATATCTAGCTAGTAATATATT
CTGAAGCAACATTTTAGCTCTATTGATACTCTTTCTAATGCTGATATGATCTTGAGTATAAGAAATGCATATGTCACTAGAATGGATAAA
ATAATGCTGCAAACTTAATGTTCTTATGCAAAATGGAACGCTAATGAAACACAGCTTACAATCGCAAATCAAAACTCACAAGTGCTCATC
TGTTGTAGATTTAGTGTAATAAGACTTAGATTGTGCTCCTTCGGATATGATTGTTTCTCAAATCTTGGCAATATTCCTTAGTCAAATCAG
GCTACTAGAATTCTGTATTGGATATATAAGAGCATGAAATTTTTAAAAATACACTTGTGATTATAAAATTAATCACAAATTTCACTTATA
CCTGCTATCAGCAGCTAGAAAACATTTTTTTTTTAAATCAAGTATTTTGTGTTTGGAATGTTAGAATGAGATCTGAATGTGGTTTCAATC
TAATTTTTTCCCAGACTACTATTTTCTTTTTTAGGTACTATTCTGAGCATACTCAACAAAACCCATGCATTTCATAAACTAATAGAAGTT
GAGGATTGTTGAATCTATTTCACTTATTTTGGCTGTGGTTTCCATCTGAAAGTAGAGGTTGTATACACCATATACTGTTCTTCATTTTAT
TAATATTTTTCTCCTTGACCTCTCATAAATTTACTTTACACAATTCTTACCCTGTACATATGTAAACATAAGTGTACGATTCTTAACCAT
GGAGTAGAGGTACTAGAATGCTTACGGCCATCTCTTTGTACAGGAACTGCATTGACTTTCAGTAAACATAAAGCCACAACTCCTACATGA
TGTTATGTACCATATGATCTGTTTTGTATCTTAAATTTGATTTACATATATTATTTATTTCTGGTAACTCACTCAGTTTATGCTGTGCTA
AATATCAATCAAGCCATGTATAAATGTGATATGATTGGCAATATGTGTTTACTTTAAACTTGTCTTTTCAAAATATTACTCAGTTTATGT
TGTACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTGTAGTGGAAACATTTATATTTTTATAATAAACATAATGAAAATATTTTTT

>26460_26460_2_EML4-EPHA3_EML4_chr2_42528532_ENST00000318522_EPHA3_chr3_89498375_ENST00000336596_length(amino acids)=748AA_BP=547
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKLEWAYGYRGK
DCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLG
TFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGIF
GKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDL
NPEREIEGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDR
NNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVG

--------------------------------------------------------------
>26460_26460_3_EML4-EPHA3_EML4_chr2_42528532_ENST00000401738_EPHA3_chr3_89498374_ENST00000336596_length(transcript)=5063nt_BP=1825nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGCAAAAATGTCAACTCGCGAAAAAAACAGCCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTT
CATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGG
AAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGA
GAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGAT
AGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACT
TGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCA
TATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCC
AACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAAT
TTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCAT
GCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGA
TGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGA
TCTGAATCCTGAAAGAGAAATAGAGGGAGGGAAGATCCCAATCAGGTGGACATCACCAGAAGCTATAGCCTACCGCAAGTTCACGTCAGC
CAGCGATGTATGGAGTTATGGGATTGTTCTCTGGGAGGTGATGTCTTATGGAGAGAGACCATACTGGGAGATGTCCAATCAGGATGTAAT
TAAAGCTGTAGATGAGGGCTATCGACTGCCACCCCCCATGGACTGCCCAGCTGCCTTGTATCAGCTGATGCTGGACTGCTGGCAGAAAGA
CAGGAACAACAGACCCAAGTTTGAGCAGATTGTTAGTATTCTGGACAAGCTTATCCGGAATCCCGGCAGCCTGAAGATCATCACCAGTGC
AGCCGCAAGGCCATCAAACCTTCTTCTGGACCAAAGCAATGTGGATATCACTACCTTCCGCACAACAGGTGACTGGCTTAATGGTGTCTG
GACAGCACACTGCAAGGAAATCTTCACGGGTGTGGAGTACAGTTCTTGTGACACAATAGCCAAGATTTCCACAGATGACATGAAAAAGGT
TGGTGTCACCGTGGTTGGGCCACAGAAGAAGATCATCAGTAGCATTAAAGCTCTAGAAACGCAATCAAAGAATGGCCCAGTTCCCGTGTA
AAGCACGGGACGGAAGTGCTTCTGGACGGAAGTGGTGGCTGTGGAAGGCGTAGCATCATCCTGCAGACAGACAATAATTCTGGAGATACT
GGTGGAAGTTCCAAGTCCAATAAGACACTCAAATATGAGTACAAATGCCTTAAAATGGAATTGAAAAACTCTTTATTTTCCCCTATCATT
TATTGGATGGGTGGGTGGGGTATTTTTTTGTAATTGCTTTTTTAAATATTAGTTAATGGATTAAATTTAATTCTTCAGCGTAAAATGGTG
AAGAACTAGCATATAGCCATTGATCATAAACTGACTATCATAAAATCAAAACAAGTGAAATAACAAAATGGACATGGTGGCTTTGTTTAG
GTAGAGCCACAAAAGAAAAGACTTGTAATATTTTTATATACAGAGGAAATCTGTAACAGGTATTTTGTTTCTTTTAAAGCAAGCAACACA
GAGGAATTTATACCTCAAACTATCTGGCCATATTTACTACCTTATCACTGCATTATTCTCTTTTATCTGTTTAAAGCATATAGAGATGAA
GTTTGTAGTTGTTTTAAGTACTACACATTTTTAAATTGTTAGCTTCCTTAAGTATATCATGTAAAGAAATGTCTTAATTTTTGAAAAAAG
TACATATTTATTTTCTTTTGAATTGTTTTTATTGTTTTCTATTTATGCCTTGATGATTTAATATGGATTTGTTACAGCCAAGTGCCAAAT
GCTCTCTCAAATTGTCAGCAATTTAACTAGACACAGATAATAATGGGTTTCTTTCAGATTTTTTGAACCATCCACTTACATATATTTTTA
AAAAATGAAATCCTTTTCCTGTTCATACACTAACCAAATCTCTCAAATCTGTTATCCCAATCATTGTTGCCTCTCCGTTTATTATAAACT
GTATGCTCACAACTTAGTGTAATATACCAGCTTGTATGCAATGGATTTTCAACCAGATAACATACCTTTCCTGCTCTGGTGCTTAGAGAC
TATCAACTCCCTCCTTTAGTGAAGGAGCCGTGTTAGAGCTTCCGAGAATAGCTCCACTGGAGAGAAGTGGAATCCTATATAGAATGCTGC
ACTAATTGACAACACAGCCTATAGGCCAATGCATGAGTAAAAAAAAAAACAATTACTGGCTCACTGGCTTTGAAAAGTCACTTACTATTG
TTGCTGAAACTTGCTGAGCTGTTTATAGAGAATGATGATAACAGAACTTTTCCTCTGTATCACTGGTGTTTAGGTGAATTAATTAAACAT
TGTGATCATTAGTACCAGGTATTATTATCTTTAAGAGTCTTCCACTTCAATGCACATGGTGCAGTTTTGGTGTGTAACTTAGAAGGATTG
AACTTCTTTGAATTTACTGGACATAACATTTTCAGAATAGTTGGTCATCTAGCAACCGCCTCAAAATGTGTAAGCAGGAGAGAAATTTCT
CATCACAGGGATTTAGACTTACTATTACATAAAGGCTAACTATGAGCTTGCTCATTAATTTTGAAAAGATGTACCTGGTGGATATCTAGC
TAGTAATATATTCTGAAGCAACATTTTAGCTCTATTGATACTCTTTCTAATGCTGATATGATCTTGAGTATAAGAAATGCATATGTCACT
AGAATGGATAAAATAATGCTGCAAACTTAATGTTCTTATGCAAAATGGAACGCTAATGAAACACAGCTTACAATCGCAAATCAAAACTCA
CAAGTGCTCATCTGTTGTAGATTTAGTGTAATAAGACTTAGATTGTGCTCCTTCGGATATGATTGTTTCTCAAATCTTGGCAATATTCCT
TAGTCAAATCAGGCTACTAGAATTCTGTATTGGATATATAAGAGCATGAAATTTTTAAAAATACACTTGTGATTATAAAATTAATCACAA
ATTTCACTTATACCTGCTATCAGCAGCTAGAAAACATTTTTTTTTTAAATCAAGTATTTTGTGTTTGGAATGTTAGAATGAGATCTGAAT
GTGGTTTCAATCTAATTTTTTCCCAGACTACTATTTTCTTTTTTAGGTACTATTCTGAGCATACTCAACAAAACCCATGCATTTCATAAA
CTAATAGAAGTTGAGGATTGTTGAATCTATTTCACTTATTTTGGCTGTGGTTTCCATCTGAAAGTAGAGGTTGTATACACCATATACTGT
TCTTCATTTTATTAATATTTTTCTCCTTGACCTCTCATAAATTTACTTTACACAATTCTTACCCTGTACATATGTAAACATAAGTGTACG
ATTCTTAACCATGGAGTAGAGGTACTAGAATGCTTACGGCCATCTCTTTGTACAGGAACTGCATTGACTTTCAGTAAACATAAAGCCACA
ACTCCTACATGATGTTATGTACCATATGATCTGTTTTGTATCTTAAATTTGATTTACATATATTATTTATTTCTGGTAACTCACTCAGTT
TATGCTGTGCTAAATATCAATCAAGCCATGTATAAATGTGATATGATTGGCAATATGTGTTTACTTTAAACTTGTCTTTTCAAAATATTA
CTCAGTTTATGTTGTACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTGTAGTGGAAACATTTATATTTTTATAATAAACATAATG

>26460_26460_3_EML4-EPHA3_EML4_chr2_42528532_ENST00000401738_EPHA3_chr3_89498374_ENST00000336596_length(amino acids)=759AA_BP=558
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKL
KLEWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSV
TLSTLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWS
GNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGK
DRKIILWDHDLNPEREIEGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALY
QLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIA

--------------------------------------------------------------
>26460_26460_4_EML4-EPHA3_EML4_chr2_42528532_ENST00000401738_EPHA3_chr3_89498375_ENST00000336596_length(transcript)=5063nt_BP=1825nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGCAAAAATGTCAACTCGCGAAAAAAACAGCCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTT
CATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGG
AAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGA
GAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGAT
AGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACT
TGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCA
TATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCC
AACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAAT
TTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCAT
GCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGA
TGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGA
TCTGAATCCTGAAAGAGAAATAGAGGGAGGGAAGATCCCAATCAGGTGGACATCACCAGAAGCTATAGCCTACCGCAAGTTCACGTCAGC
CAGCGATGTATGGAGTTATGGGATTGTTCTCTGGGAGGTGATGTCTTATGGAGAGAGACCATACTGGGAGATGTCCAATCAGGATGTAAT
TAAAGCTGTAGATGAGGGCTATCGACTGCCACCCCCCATGGACTGCCCAGCTGCCTTGTATCAGCTGATGCTGGACTGCTGGCAGAAAGA
CAGGAACAACAGACCCAAGTTTGAGCAGATTGTTAGTATTCTGGACAAGCTTATCCGGAATCCCGGCAGCCTGAAGATCATCACCAGTGC
AGCCGCAAGGCCATCAAACCTTCTTCTGGACCAAAGCAATGTGGATATCACTACCTTCCGCACAACAGGTGACTGGCTTAATGGTGTCTG
GACAGCACACTGCAAGGAAATCTTCACGGGTGTGGAGTACAGTTCTTGTGACACAATAGCCAAGATTTCCACAGATGACATGAAAAAGGT
TGGTGTCACCGTGGTTGGGCCACAGAAGAAGATCATCAGTAGCATTAAAGCTCTAGAAACGCAATCAAAGAATGGCCCAGTTCCCGTGTA
AAGCACGGGACGGAAGTGCTTCTGGACGGAAGTGGTGGCTGTGGAAGGCGTAGCATCATCCTGCAGACAGACAATAATTCTGGAGATACT
GGTGGAAGTTCCAAGTCCAATAAGACACTCAAATATGAGTACAAATGCCTTAAAATGGAATTGAAAAACTCTTTATTTTCCCCTATCATT
TATTGGATGGGTGGGTGGGGTATTTTTTTGTAATTGCTTTTTTAAATATTAGTTAATGGATTAAATTTAATTCTTCAGCGTAAAATGGTG
AAGAACTAGCATATAGCCATTGATCATAAACTGACTATCATAAAATCAAAACAAGTGAAATAACAAAATGGACATGGTGGCTTTGTTTAG
GTAGAGCCACAAAAGAAAAGACTTGTAATATTTTTATATACAGAGGAAATCTGTAACAGGTATTTTGTTTCTTTTAAAGCAAGCAACACA
GAGGAATTTATACCTCAAACTATCTGGCCATATTTACTACCTTATCACTGCATTATTCTCTTTTATCTGTTTAAAGCATATAGAGATGAA
GTTTGTAGTTGTTTTAAGTACTACACATTTTTAAATTGTTAGCTTCCTTAAGTATATCATGTAAAGAAATGTCTTAATTTTTGAAAAAAG
TACATATTTATTTTCTTTTGAATTGTTTTTATTGTTTTCTATTTATGCCTTGATGATTTAATATGGATTTGTTACAGCCAAGTGCCAAAT
GCTCTCTCAAATTGTCAGCAATTTAACTAGACACAGATAATAATGGGTTTCTTTCAGATTTTTTGAACCATCCACTTACATATATTTTTA
AAAAATGAAATCCTTTTCCTGTTCATACACTAACCAAATCTCTCAAATCTGTTATCCCAATCATTGTTGCCTCTCCGTTTATTATAAACT
GTATGCTCACAACTTAGTGTAATATACCAGCTTGTATGCAATGGATTTTCAACCAGATAACATACCTTTCCTGCTCTGGTGCTTAGAGAC
TATCAACTCCCTCCTTTAGTGAAGGAGCCGTGTTAGAGCTTCCGAGAATAGCTCCACTGGAGAGAAGTGGAATCCTATATAGAATGCTGC
ACTAATTGACAACACAGCCTATAGGCCAATGCATGAGTAAAAAAAAAAACAATTACTGGCTCACTGGCTTTGAAAAGTCACTTACTATTG
TTGCTGAAACTTGCTGAGCTGTTTATAGAGAATGATGATAACAGAACTTTTCCTCTGTATCACTGGTGTTTAGGTGAATTAATTAAACAT
TGTGATCATTAGTACCAGGTATTATTATCTTTAAGAGTCTTCCACTTCAATGCACATGGTGCAGTTTTGGTGTGTAACTTAGAAGGATTG
AACTTCTTTGAATTTACTGGACATAACATTTTCAGAATAGTTGGTCATCTAGCAACCGCCTCAAAATGTGTAAGCAGGAGAGAAATTTCT
CATCACAGGGATTTAGACTTACTATTACATAAAGGCTAACTATGAGCTTGCTCATTAATTTTGAAAAGATGTACCTGGTGGATATCTAGC
TAGTAATATATTCTGAAGCAACATTTTAGCTCTATTGATACTCTTTCTAATGCTGATATGATCTTGAGTATAAGAAATGCATATGTCACT
AGAATGGATAAAATAATGCTGCAAACTTAATGTTCTTATGCAAAATGGAACGCTAATGAAACACAGCTTACAATCGCAAATCAAAACTCA
CAAGTGCTCATCTGTTGTAGATTTAGTGTAATAAGACTTAGATTGTGCTCCTTCGGATATGATTGTTTCTCAAATCTTGGCAATATTCCT
TAGTCAAATCAGGCTACTAGAATTCTGTATTGGATATATAAGAGCATGAAATTTTTAAAAATACACTTGTGATTATAAAATTAATCACAA
ATTTCACTTATACCTGCTATCAGCAGCTAGAAAACATTTTTTTTTTAAATCAAGTATTTTGTGTTTGGAATGTTAGAATGAGATCTGAAT
GTGGTTTCAATCTAATTTTTTCCCAGACTACTATTTTCTTTTTTAGGTACTATTCTGAGCATACTCAACAAAACCCATGCATTTCATAAA
CTAATAGAAGTTGAGGATTGTTGAATCTATTTCACTTATTTTGGCTGTGGTTTCCATCTGAAAGTAGAGGTTGTATACACCATATACTGT
TCTTCATTTTATTAATATTTTTCTCCTTGACCTCTCATAAATTTACTTTACACAATTCTTACCCTGTACATATGTAAACATAAGTGTACG
ATTCTTAACCATGGAGTAGAGGTACTAGAATGCTTACGGCCATCTCTTTGTACAGGAACTGCATTGACTTTCAGTAAACATAAAGCCACA
ACTCCTACATGATGTTATGTACCATATGATCTGTTTTGTATCTTAAATTTGATTTACATATATTATTTATTTCTGGTAACTCACTCAGTT
TATGCTGTGCTAAATATCAATCAAGCCATGTATAAATGTGATATGATTGGCAATATGTGTTTACTTTAAACTTGTCTTTTCAAAATATTA
CTCAGTTTATGTTGTACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTGTAGTGGAAACATTTATATTTTTATAATAAACATAATG

>26460_26460_4_EML4-EPHA3_EML4_chr2_42528532_ENST00000401738_EPHA3_chr3_89498375_ENST00000336596_length(amino acids)=759AA_BP=558
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKL
KLEWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSV
TLSTLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWS
GNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGK
DRKIILWDHDLNPEREIEGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALY
QLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIA

--------------------------------------------------------------
>26460_26460_5_EML4-EPHA3_EML4_chr2_42528532_ENST00000402711_EPHA3_chr3_89498374_ENST00000336596_length(transcript)=4964nt_BP=1726nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTC
CGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTG
TAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCA
GCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGT
GGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTT
TGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTAC
TGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGC
AAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAA
ATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATG
GAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGT
GTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCC
TGAAAGAGAAATAGAGGGAGGGAAGATCCCAATCAGGTGGACATCACCAGAAGCTATAGCCTACCGCAAGTTCACGTCAGCCAGCGATGT
ATGGAGTTATGGGATTGTTCTCTGGGAGGTGATGTCTTATGGAGAGAGACCATACTGGGAGATGTCCAATCAGGATGTAATTAAAGCTGT
AGATGAGGGCTATCGACTGCCACCCCCCATGGACTGCCCAGCTGCCTTGTATCAGCTGATGCTGGACTGCTGGCAGAAAGACAGGAACAA
CAGACCCAAGTTTGAGCAGATTGTTAGTATTCTGGACAAGCTTATCCGGAATCCCGGCAGCCTGAAGATCATCACCAGTGCAGCCGCAAG
GCCATCAAACCTTCTTCTGGACCAAAGCAATGTGGATATCACTACCTTCCGCACAACAGGTGACTGGCTTAATGGTGTCTGGACAGCACA
CTGCAAGGAAATCTTCACGGGTGTGGAGTACAGTTCTTGTGACACAATAGCCAAGATTTCCACAGATGACATGAAAAAGGTTGGTGTCAC
CGTGGTTGGGCCACAGAAGAAGATCATCAGTAGCATTAAAGCTCTAGAAACGCAATCAAAGAATGGCCCAGTTCCCGTGTAAAGCACGGG
ACGGAAGTGCTTCTGGACGGAAGTGGTGGCTGTGGAAGGCGTAGCATCATCCTGCAGACAGACAATAATTCTGGAGATACTGGTGGAAGT
TCCAAGTCCAATAAGACACTCAAATATGAGTACAAATGCCTTAAAATGGAATTGAAAAACTCTTTATTTTCCCCTATCATTTATTGGATG
GGTGGGTGGGGTATTTTTTTGTAATTGCTTTTTTAAATATTAGTTAATGGATTAAATTTAATTCTTCAGCGTAAAATGGTGAAGAACTAG
CATATAGCCATTGATCATAAACTGACTATCATAAAATCAAAACAAGTGAAATAACAAAATGGACATGGTGGCTTTGTTTAGGTAGAGCCA
CAAAAGAAAAGACTTGTAATATTTTTATATACAGAGGAAATCTGTAACAGGTATTTTGTTTCTTTTAAAGCAAGCAACACAGAGGAATTT
ATACCTCAAACTATCTGGCCATATTTACTACCTTATCACTGCATTATTCTCTTTTATCTGTTTAAAGCATATAGAGATGAAGTTTGTAGT
TGTTTTAAGTACTACACATTTTTAAATTGTTAGCTTCCTTAAGTATATCATGTAAAGAAATGTCTTAATTTTTGAAAAAAGTACATATTT
ATTTTCTTTTGAATTGTTTTTATTGTTTTCTATTTATGCCTTGATGATTTAATATGGATTTGTTACAGCCAAGTGCCAAATGCTCTCTCA
AATTGTCAGCAATTTAACTAGACACAGATAATAATGGGTTTCTTTCAGATTTTTTGAACCATCCACTTACATATATTTTTAAAAAATGAA
ATCCTTTTCCTGTTCATACACTAACCAAATCTCTCAAATCTGTTATCCCAATCATTGTTGCCTCTCCGTTTATTATAAACTGTATGCTCA
CAACTTAGTGTAATATACCAGCTTGTATGCAATGGATTTTCAACCAGATAACATACCTTTCCTGCTCTGGTGCTTAGAGACTATCAACTC
CCTCCTTTAGTGAAGGAGCCGTGTTAGAGCTTCCGAGAATAGCTCCACTGGAGAGAAGTGGAATCCTATATAGAATGCTGCACTAATTGA
CAACACAGCCTATAGGCCAATGCATGAGTAAAAAAAAAAACAATTACTGGCTCACTGGCTTTGAAAAGTCACTTACTATTGTTGCTGAAA
CTTGCTGAGCTGTTTATAGAGAATGATGATAACAGAACTTTTCCTCTGTATCACTGGTGTTTAGGTGAATTAATTAAACATTGTGATCAT
TAGTACCAGGTATTATTATCTTTAAGAGTCTTCCACTTCAATGCACATGGTGCAGTTTTGGTGTGTAACTTAGAAGGATTGAACTTCTTT
GAATTTACTGGACATAACATTTTCAGAATAGTTGGTCATCTAGCAACCGCCTCAAAATGTGTAAGCAGGAGAGAAATTTCTCATCACAGG
GATTTAGACTTACTATTACATAAAGGCTAACTATGAGCTTGCTCATTAATTTTGAAAAGATGTACCTGGTGGATATCTAGCTAGTAATAT
ATTCTGAAGCAACATTTTAGCTCTATTGATACTCTTTCTAATGCTGATATGATCTTGAGTATAAGAAATGCATATGTCACTAGAATGGAT
AAAATAATGCTGCAAACTTAATGTTCTTATGCAAAATGGAACGCTAATGAAACACAGCTTACAATCGCAAATCAAAACTCACAAGTGCTC
ATCTGTTGTAGATTTAGTGTAATAAGACTTAGATTGTGCTCCTTCGGATATGATTGTTTCTCAAATCTTGGCAATATTCCTTAGTCAAAT
CAGGCTACTAGAATTCTGTATTGGATATATAAGAGCATGAAATTTTTAAAAATACACTTGTGATTATAAAATTAATCACAAATTTCACTT
ATACCTGCTATCAGCAGCTAGAAAACATTTTTTTTTTAAATCAAGTATTTTGTGTTTGGAATGTTAGAATGAGATCTGAATGTGGTTTCA
ATCTAATTTTTTCCCAGACTACTATTTTCTTTTTTAGGTACTATTCTGAGCATACTCAACAAAACCCATGCATTTCATAAACTAATAGAA
GTTGAGGATTGTTGAATCTATTTCACTTATTTTGGCTGTGGTTTCCATCTGAAAGTAGAGGTTGTATACACCATATACTGTTCTTCATTT
TATTAATATTTTTCTCCTTGACCTCTCATAAATTTACTTTACACAATTCTTACCCTGTACATATGTAAACATAAGTGTACGATTCTTAAC
CATGGAGTAGAGGTACTAGAATGCTTACGGCCATCTCTTTGTACAGGAACTGCATTGACTTTCAGTAAACATAAAGCCACAACTCCTACA
TGATGTTATGTACCATATGATCTGTTTTGTATCTTAAATTTGATTTACATATATTATTTATTTCTGGTAACTCACTCAGTTTATGCTGTG
CTAAATATCAATCAAGCCATGTATAAATGTGATATGATTGGCAATATGTGTTTACTTTAAACTTGTCTTTTCAAAATATTACTCAGTTTA
TGTTGTACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTGTAGTGGAAACATTTATATTTTTATAATAAACATAATGAAAATATTT

>26460_26460_5_EML4-EPHA3_EML4_chr2_42528532_ENST00000402711_EPHA3_chr3_89498374_ENST00000336596_length(amino acids)=690AA_BP=489
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQEGEYIKMFMRGRPITM
FIPSDVDNYDDIRTELPPEKLKLEWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQ
IAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFH
PTDANTIITCGKSHIFFWTWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAH
DGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDV
IKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGV

--------------------------------------------------------------
>26460_26460_6_EML4-EPHA3_EML4_chr2_42528532_ENST00000402711_EPHA3_chr3_89498375_ENST00000336596_length(transcript)=4964nt_BP=1726nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTC
CGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTG
TAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCA
GCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGT
GGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTT
TGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTAC
TGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGC
AAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAA
ATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATG
GAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGT
GTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCC
TGAAAGAGAAATAGAGGGAGGGAAGATCCCAATCAGGTGGACATCACCAGAAGCTATAGCCTACCGCAAGTTCACGTCAGCCAGCGATGT
ATGGAGTTATGGGATTGTTCTCTGGGAGGTGATGTCTTATGGAGAGAGACCATACTGGGAGATGTCCAATCAGGATGTAATTAAAGCTGT
AGATGAGGGCTATCGACTGCCACCCCCCATGGACTGCCCAGCTGCCTTGTATCAGCTGATGCTGGACTGCTGGCAGAAAGACAGGAACAA
CAGACCCAAGTTTGAGCAGATTGTTAGTATTCTGGACAAGCTTATCCGGAATCCCGGCAGCCTGAAGATCATCACCAGTGCAGCCGCAAG
GCCATCAAACCTTCTTCTGGACCAAAGCAATGTGGATATCACTACCTTCCGCACAACAGGTGACTGGCTTAATGGTGTCTGGACAGCACA
CTGCAAGGAAATCTTCACGGGTGTGGAGTACAGTTCTTGTGACACAATAGCCAAGATTTCCACAGATGACATGAAAAAGGTTGGTGTCAC
CGTGGTTGGGCCACAGAAGAAGATCATCAGTAGCATTAAAGCTCTAGAAACGCAATCAAAGAATGGCCCAGTTCCCGTGTAAAGCACGGG
ACGGAAGTGCTTCTGGACGGAAGTGGTGGCTGTGGAAGGCGTAGCATCATCCTGCAGACAGACAATAATTCTGGAGATACTGGTGGAAGT
TCCAAGTCCAATAAGACACTCAAATATGAGTACAAATGCCTTAAAATGGAATTGAAAAACTCTTTATTTTCCCCTATCATTTATTGGATG
GGTGGGTGGGGTATTTTTTTGTAATTGCTTTTTTAAATATTAGTTAATGGATTAAATTTAATTCTTCAGCGTAAAATGGTGAAGAACTAG
CATATAGCCATTGATCATAAACTGACTATCATAAAATCAAAACAAGTGAAATAACAAAATGGACATGGTGGCTTTGTTTAGGTAGAGCCA
CAAAAGAAAAGACTTGTAATATTTTTATATACAGAGGAAATCTGTAACAGGTATTTTGTTTCTTTTAAAGCAAGCAACACAGAGGAATTT
ATACCTCAAACTATCTGGCCATATTTACTACCTTATCACTGCATTATTCTCTTTTATCTGTTTAAAGCATATAGAGATGAAGTTTGTAGT
TGTTTTAAGTACTACACATTTTTAAATTGTTAGCTTCCTTAAGTATATCATGTAAAGAAATGTCTTAATTTTTGAAAAAAGTACATATTT
ATTTTCTTTTGAATTGTTTTTATTGTTTTCTATTTATGCCTTGATGATTTAATATGGATTTGTTACAGCCAAGTGCCAAATGCTCTCTCA
AATTGTCAGCAATTTAACTAGACACAGATAATAATGGGTTTCTTTCAGATTTTTTGAACCATCCACTTACATATATTTTTAAAAAATGAA
ATCCTTTTCCTGTTCATACACTAACCAAATCTCTCAAATCTGTTATCCCAATCATTGTTGCCTCTCCGTTTATTATAAACTGTATGCTCA
CAACTTAGTGTAATATACCAGCTTGTATGCAATGGATTTTCAACCAGATAACATACCTTTCCTGCTCTGGTGCTTAGAGACTATCAACTC
CCTCCTTTAGTGAAGGAGCCGTGTTAGAGCTTCCGAGAATAGCTCCACTGGAGAGAAGTGGAATCCTATATAGAATGCTGCACTAATTGA
CAACACAGCCTATAGGCCAATGCATGAGTAAAAAAAAAAACAATTACTGGCTCACTGGCTTTGAAAAGTCACTTACTATTGTTGCTGAAA
CTTGCTGAGCTGTTTATAGAGAATGATGATAACAGAACTTTTCCTCTGTATCACTGGTGTTTAGGTGAATTAATTAAACATTGTGATCAT
TAGTACCAGGTATTATTATCTTTAAGAGTCTTCCACTTCAATGCACATGGTGCAGTTTTGGTGTGTAACTTAGAAGGATTGAACTTCTTT
GAATTTACTGGACATAACATTTTCAGAATAGTTGGTCATCTAGCAACCGCCTCAAAATGTGTAAGCAGGAGAGAAATTTCTCATCACAGG
GATTTAGACTTACTATTACATAAAGGCTAACTATGAGCTTGCTCATTAATTTTGAAAAGATGTACCTGGTGGATATCTAGCTAGTAATAT
ATTCTGAAGCAACATTTTAGCTCTATTGATACTCTTTCTAATGCTGATATGATCTTGAGTATAAGAAATGCATATGTCACTAGAATGGAT
AAAATAATGCTGCAAACTTAATGTTCTTATGCAAAATGGAACGCTAATGAAACACAGCTTACAATCGCAAATCAAAACTCACAAGTGCTC
ATCTGTTGTAGATTTAGTGTAATAAGACTTAGATTGTGCTCCTTCGGATATGATTGTTTCTCAAATCTTGGCAATATTCCTTAGTCAAAT
CAGGCTACTAGAATTCTGTATTGGATATATAAGAGCATGAAATTTTTAAAAATACACTTGTGATTATAAAATTAATCACAAATTTCACTT
ATACCTGCTATCAGCAGCTAGAAAACATTTTTTTTTTAAATCAAGTATTTTGTGTTTGGAATGTTAGAATGAGATCTGAATGTGGTTTCA
ATCTAATTTTTTCCCAGACTACTATTTTCTTTTTTAGGTACTATTCTGAGCATACTCAACAAAACCCATGCATTTCATAAACTAATAGAA
GTTGAGGATTGTTGAATCTATTTCACTTATTTTGGCTGTGGTTTCCATCTGAAAGTAGAGGTTGTATACACCATATACTGTTCTTCATTT
TATTAATATTTTTCTCCTTGACCTCTCATAAATTTACTTTACACAATTCTTACCCTGTACATATGTAAACATAAGTGTACGATTCTTAAC
CATGGAGTAGAGGTACTAGAATGCTTACGGCCATCTCTTTGTACAGGAACTGCATTGACTTTCAGTAAACATAAAGCCACAACTCCTACA
TGATGTTATGTACCATATGATCTGTTTTGTATCTTAAATTTGATTTACATATATTATTTATTTCTGGTAACTCACTCAGTTTATGCTGTG
CTAAATATCAATCAAGCCATGTATAAATGTGATATGATTGGCAATATGTGTTTACTTTAAACTTGTCTTTTCAAAATATTACTCAGTTTA
TGTTGTACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTGTAGTGGAAACATTTATATTTTTATAATAAACATAATGAAAATATTT

>26460_26460_6_EML4-EPHA3_EML4_chr2_42528532_ENST00000402711_EPHA3_chr3_89498375_ENST00000336596_length(amino acids)=690AA_BP=489
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQEGEYIKMFMRGRPITM
FIPSDVDNYDDIRTELPPEKLKLEWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQ
IAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFH
PTDANTIITCGKSHIFFWTWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAH
DGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDV
IKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGV

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Fusion Gene PPI Analysis for EML4-EPHA3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EML4-EPHA3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EML4-EPHA3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource