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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:EPB41L4B-PTBP3 (FusionGDB2 ID:26862)

Fusion Gene Summary for EPB41L4B-PTBP3

Fusion gene summary

Fusion gene information	Fusion gene name: EPB41L4B-PTBP3
	Fusion gene ID: 26862
		Hgene	Tgene
	Gene symbol	EPB41L4B	PTBP3
	Gene ID	54566	9991
	Gene name	erythrocyte membrane protein band 4.1 like 4B	polypyrimidine tract binding protein 3
	Synonyms	CG1\|EHM2\|LULU2	ROD1
	Cytomap	9q31.3	9q32
	Type of gene	protein-coding	protein-coding
	Description	band 4.1-like protein 4BFERM-containing protein CG1	polypyrimidine tract-binding protein 3ROD1 regulator of differentiation 1fission yeast differentiation regulatorregulator of differentiation 1
	Modification date	20200313	20200313
	UniProtAcc	Q9H329	.
	Ensembl transtripts involved in fusion gene	ENST00000374557, ENST00000374566,	ENST00000343327, ENST00000374255, ENST00000374257, ENST00000487997, ENST00000334318, ENST00000458258,
Fusion gene scores	* DoF score	6 X 9 X 4=216	12 X 9 X 7=756
	# samples	9	15
	** MAII score	log2(9/216*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(15/756*10)=-2.33342373372519 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: EPB41L4B [Title/Abstract] AND PTBP3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	EPB41L4B(112082421)-PTBP3(115060196), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	EPB41L4B	GO:0031032	actomyosin structure organization	22006950
Hgene	EPB41L4B	GO:0042060	wound healing	23664528
Tgene	PTBP3	GO:0033119	negative regulation of RNA splicing	18335065

Fusion gene breakpoints across EPB41L4B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PTBP3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-ZF-A9RD-01A	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-

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Fusion Gene ORF analysis for EPB41L4B-PTBP3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000374557	ENST00000343327	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
5CDS-5UTR	ENST00000374557	ENST00000374255	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
5CDS-5UTR	ENST00000374557	ENST00000374257	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
5CDS-5UTR	ENST00000374566	ENST00000343327	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
5CDS-5UTR	ENST00000374566	ENST00000374255	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
5CDS-5UTR	ENST00000374566	ENST00000374257	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
5CDS-intron	ENST00000374557	ENST00000487997	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
5CDS-intron	ENST00000374566	ENST00000487997	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
In-frame	ENST00000374557	ENST00000334318	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
In-frame	ENST00000374557	ENST00000458258	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
In-frame	ENST00000374566	ENST00000334318	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-
In-frame	ENST00000374566	ENST00000458258	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000374566	EPB41L4B	chr9	112082421	-	ENST00000458258	PTBP3	chr9	115060196	-	7857	824	518	2440	640
ENST00000374566	EPB41L4B	chr9	112082421	-	ENST00000334318	PTBP3	chr9	115060196	-	7866	824	518	2449	643
ENST00000374557	EPB41L4B	chr9	112082421	-	ENST00000458258	PTBP3	chr9	115060196	-	7857	824	518	2440	640
ENST00000374557	EPB41L4B	chr9	112082421	-	ENST00000334318	PTBP3	chr9	115060196	-	7866	824	518	2449	643

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000374566	ENST00000458258	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-	0.000310712	0.99968934
ENST00000374566	ENST00000334318	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-	0.000282458	0.99971753
ENST00000374557	ENST00000458258	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-	0.000310712	0.99968934
ENST00000374557	ENST00000334318	EPB41L4B	chr9	112082421	-	PTBP3	chr9	115060196	-	0.000282458	0.99971753

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Fusion Genomic Features for EPB41L4B-PTBP3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for EPB41L4B-PTBP3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:112082421/chr9:115060196)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
EPB41L4B Q9H329	.
FUNCTION: Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927). {ECO:0000250\|UniProtKB:Q9JMC8, ECO:0000269\|PubMed:14521927, ECO:0000269\|PubMed:22006950, ECO:0000269\|PubMed:23664528}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000334318

182_258

556.0

Domain

RRM 2

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000334318

358_432

556.0

Domain

RRM 3

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000334318

475_550

556.0

Domain

RRM 4

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000334318

59_143

556.0

Domain

RRM 1

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000343327

182_258

458.0

Domain

RRM 2

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000343327

358_432

458.0

Domain

RRM 3

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000343327

475_550

458.0

Domain

RRM 4

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000343327

59_143

458.0

Domain

RRM 1

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374255

182_258

553.0

Domain

RRM 2

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374255

358_432

553.0

Domain

RRM 3

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374255

475_550

553.0

Domain

RRM 4

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374255

59_143

553.0

Domain

RRM 1

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374257

182_258

525.0

Domain

RRM 2

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374257

358_432

525.0

Domain

RRM 3

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374257

475_550

525.0

Domain

RRM 4

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000374257

59_143

525.0

Domain

RRM 1

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000458258

182_258

559.0

Domain

RRM 2

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000458258

358_432

559.0

Domain

RRM 3

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000458258

475_550

559.0

Domain

RRM 4

Tgene

PTBP3

chr9:112082421

chr9:115060196

ENST00000458258

59_143

559.0

Domain

RRM 1

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

EPB41L4B

chr9:112082421

chr9:115060196

ENST00000374557

504_517

102

519.0

Compositional bias

Note=His-rich

Hgene

EPB41L4B

chr9:112082421

chr9:115060196

ENST00000374566

504_517

102

901.0

Compositional bias

Note=His-rich

Hgene

EPB41L4B

chr9:112082421

chr9:115060196

ENST00000374557

85_369

102

519.0

Domain

FERM

Hgene

EPB41L4B

chr9:112082421

chr9:115060196

ENST00000374566

85_369

102

901.0

Domain

FERM

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Fusion Gene Sequence for EPB41L4B-PTBP3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>26862_26862_1_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374557_PTBP3_chr9_115060196_ENST00000334318_length(transcript)=7866nt_BP=824nt
GGAAAAGGCGCCTTGGGAGCGGGCGCTCGGCGGGGCCTCCTCGGGCCCCGGGCGCGGCGCGGCGAGTGGGAGCGAGCGCGCCAGGACCAC
GCAGGCGCCCTGCTCCGGCTGGCCCTCGGCCGGCGCGCGGCGCGGGAGCAGCCCGCAGCCCGCCTCCCGCGCCCCCGGCAGCCCCCTGGC
AGCCCGCAGCCGCCCGTCCGGAGCAGCCCCTCGGCAGCCCGCGCAGGCCGCCGGCCCGGGAGAGCGCGCGGCGGCGGCGGCGGCGGGACG
GCCCCGAGCGCGCCCTCCCGCCTGCGGCCACTCGCAGCCGGCGCTGGCCGGGCCGGCGCGCCCCGCAGGCGGCTAGAGCGCGGCCTCGGC
CTCGGCGCGGGCTTGCCCCGGGCCGTAGCCCGCGAGAGGCGGCGCGGGCGGCCGAGGGCACTGACGGCGTCGCGGGACGCTCCCGGGCGG
CGGCGCAGCGGCAGCGGCAGCGGCAGCGGCAGCGCAGGGGGCGGAGGCAGGGGGCGCCCCCAGCCAGGATGCTGCGGTTCCTGCGCCGGA
CCTTTGGCCGCCGCTCCATGCAGCGCTACGCGCGGGGCGCGGCGGGGCGCGGGGCCGCCGGGCTGGGGGACGAGCGCGATGGGGGGCCAC
GGGGGGGCCCGGCCGCCGCCGCCTCCTCCTCGGCGCTGCCCGCCGCGCCCGGGGGCAGCGTGTTCCCGGCGGGCGGCGGGCCCCTGCTCA
CCGGCGGCGCGGCCGTGCACATCTCCGCCGCCGGCGCCGCCAAGGCCACCCTCTACTGCCGCGTCTTCCTGCTCGACGGGACCGAAGTGA
GCGTGGACCTGCCGCGGGGATCTGATGAGCTTCTTTCTTCTGGCATCATTAACGGACCTTTTACCATGAATAGTTCTACTCCTTCTACAG
GTGTGTATGCTAATGGGAATGACAGCAAGAAATTTAAACGAGATAGACCTCCCTGTTCGCCTTCCCGTGTTCTCCATCTTCGAAAAATTC
CATGTGATGTCACCGAAGCAGAGATCATATCATTAGGTCTACCATTTGGCAAAGTAACTAATCTTTTGATGTTGAAAGGAAAAAGCCAGG
CTTTCTTAGAAATGGCTTCTGAGGAAGCTGCCGTTACTATGGTGAATTATTACACTCCTATTACTCCTCACCTTCGAAGCCAGCCTGTTT
ATATTCAGTATTCCAATCACAGAGAACTTAAGACTGACAATCTACCTAATCAAGCTCGAGCCCAAGCTGCACTGCAGGCTGTCAGTGCCG
TCCAATCAGGAAGCCTGGCCCTTTCTGGAGGTCCTTCCAATGAAGGCACAGTCCTACCTGGGCAGAGCCCTGTGCTTCGAATAATTATTG
AAAACCTCTTTTACCCTGTTACCCTGGAAGTTCTTCATCAGATATTTTCTAAATTTGGCACAGTCTTGAAGATTATCACCTTTACAAAGA
ATAATCAGTTTCAAGCCTTGCTTCAGTATGCTGACCCAGTAAATGCACATTATGCCAAAATGGCTCTGGATGGCCAGAATATCTATAATG
CATGCTGCACTCTGCGCATTGACTTCTCCAAGCTCACCAGCCTTAATGTGAAATATAATAATGACAAAAGCAGAGACTTCACTCGCTTAG
ACCTTCCTACTGGTGATGGCCAGCCATCCCTTGAACCCCCTATGGCTGCTGCTTTTGGTGCACCGGGTATAATTTCTTCACCATATGCAG
GGGCTGCTGGATTTGCCCCAGCCATTGGATTTCCTCAAGCTACAGGTCTATCAGTTCCAGCTGTTCCTGGAGCTCTTGGTCCTCTCACAA
TCACCTCTTCTGCTGTCACTGGAAGGATGGCCATTCCTGGGGCTAGTGGTATACCAGGAAATTCTGTTCTACTCGTCACAAATCTCAATC
CTGATCTTATCACACCACATGGGCTTTTTATCCTATTTGGAGTCTATGGTGATGTACATCGAGTGAAGATTATGTTTAATAAGAAAGAAA
ATGCCTTGGTTCAGATGGCGGATGCAAATCAAGCTCAGCTAGCAATGAACCATCTAAGTGGTCAGAGACTTTATGGGAAAGTGCTTCGTG
CTACACTGTCCAAACATCAAGCAGTACAGCTTCCTCGAGAGGGACAAGAAGACCAAGGTCTGACTAAGGATTTCAGCAATAGTCCTTTGC
ATCGCTTTAAAAAGCCGGGCTCTAAAAACTTCCAGAATATCTTTCCACCATCAGCCACTCTGCATCTTTCCAACATTCCCCCTTCTGTTA
CAGTGGATGATCTGAAGAACCTTTTCATAGAAGCTGGATGTTCAGTGAAGGCTTTTAAATTCTTTCAGAAAGATCGCAAAATGGCGCTCA
TTCAATTGGGATCTGTGGAAGAAGCAATTCAGGCCCTCATTGAGCTTCATAACCATGACCTTGGAGAAAATCACCACCTCAGAGTTTCCT
TCTCAAAATCTACAATCTGACTTTTCTGTGAATTTTTCTCCTAAAACTGGACCATAATTTCAGTAAAACCTTCAGACATAGACTGAAGCA
GCTCAAGACCAATTTTGCCTCTTTCACAAAAATAACTCTGAGTTTGATATTCAAGTATATTTTAAAAATCAAGGGATTTTTTTTTTTTGT
ATTCCCCCTGCCCCCGCCAGTCAAAGGTTTCTTTTCCCTTTTTACCATGGTTTCTACAAAAATAACCTTCAGGAAAAAGAAAATCAGGAA
AAAAATTTTTTTTCAATAATCTTATTCCCTATATTAAATTAGATTTGAAGAGGATTAACGTTGTTTTAGTTTGGGTCCAGATCAGCCTTA
TACAACATTTCTAAACTCATTTGTACTTTTAAAAAATTTAAACACAGACTTCTAAAATTACTTGATGTAAGTAATTTAAATCACTTATGA
CCAAGTTATTAACCTTATGAATCAGAAGTCTGACCCTTGTAGGAAATTATATTCACATATAAAGTACATCAGATCTTTGCCATATATTGA
TGGTTATTATGCATAAACACATTGAGTTGTGTTGGAAGCAGATTTATAAACCTGCATGTTTTCTTTGAATGATTTCTTTTTTTCACTGTA
AGACACTCCTTTAAATAATGCCTATCTTTAACTTTTTAAGACTATTTGGAAAAATGCAGTGTCTCAGCTGTCCCCAGGGAAATTAAGTGG
AATTCAACTAAGATCTGTTAATAAGATGTCAGAATAACTAATAATTTTATTAGGAAAAAATCATGTTTTAAATTTCAAAATGACACTTAT
TTGTCAAGTAATATGATCTTGGAAAATTTTAAAGAAAAATAATCCTACTTATAAACTACTTTTTTATAATTGTTTTCAGAAAAAAAGTTT
ACAGTCTTAAGGAAAATATTCAGGTCTATCATATGGTTTGACAGATTTTTTAAAAGTTATTTTTGGTAAGGTCTTCTTTTAGAAAAAAAT
TAATCTCAAGGGTTTTTTGTACCACTATAATCTCTAATACTTACTCAGAATTACTGTGTATTTACTTAATTTCTTATTATGTGCCTTATT
ATGTGCTTAAGATACAATAGGTTAGAGTTTAATCTAAATATCTTGAAAGCTATATTGTGGGCTTGGTAAGCATTTTGTTTTTTCTTTCTC
TGTTTTGGTAAGGATTTAAAATTTTTTTCATTGCAATTTTAAGTGGTTTTCAATAAGTAATAGTTTTTATCAAATTTTTGGTGCTTGGTG
CAGAGACGGTGTGGGGAAGGGTGAATGGTTTTGGGAATAATTCAGTGCACACCTGTAGGCCTCTTTACATTGTGACTGATAGGGGTTATT
GCATATCAATTTGGGGCTGTAGAGTGCAATCTCAGTTTCATCTTTTTCACCCATCAGAATTTGTCTCAGGATTACTTGGTTTTTCTCAGT
CCTCAAGCGAGAACTTGCTTTTCTTTGTTAATGTGACTTTCATTACTGAGTACCCACGTATTTGGAGTATGAGAAGGTGGGTTATTTCTC
ATACTCTGTCCCTCTCTTTTTCATTGAATGTAAGAGTACATTTTAATGTTGCTTCAGTGATTGTATAATGTAAAATTGTTTCTTTTTAAT
AAGAAACTTTGCTATTATTTCTTCAATTGTTGATCAGAATTTTTTAAAGCAGAATTTGTCAAAAGGGTCATTTTTTTGTCTACCCCTTTT
ACACTTTTCAGATTCTCAAAGTGTCTCATCTCAACTTTTAAAAGAATAAAGAATATCTTGCTGGGCATGGTGGTGTGCGCCTGTGCGCCT
GTAGTCCCAGCTACAGGCTGAGCCTGTAGGCAGGAGGCTACAGGCAGGAGGATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGCGCTAT
GATCACATTTGTGAATAGCCACTTCACTCCAGCCCTGGAACATAGTGTGACCCCTTCTCTTAAAAGTAAAAATTAAGAAAATCTCAATCT
CTTTGCTGTATTCCAGTGATTAATTTGAACATAGGGAGGTTTTTACAGAAGAAATTTTACCAAAAAATAGAGACTGCAAGAGATGATACA
GATTGTTTAAAAAGCAGAATTCACTCACCACTGAGCAACACTTAGTTGGTAGAATAGAAAGGAGGGATACTAAGTTAAGACTTTTCAAAT
GGATCAGTTTGGCTGAATAGATAGATATACTCATGTATGTAGTTGTGGGAGTTTTTAGTTTTTTGTTTTTTTACTTATGAAATAAGTTTT
GACCTAGACACAAGGGGTATATGAAGGAGGAAAAAAATTTCTTTGCAAAATCTCCCAAAACTTGCTTTTTTTTCCCTTCCACACAGGCAC
TATTATAATTTTCAGTGCCATGTTAAATTGGATTATTTCATTTACTTTAAGTTAGGAATTACTGTGTAATTTATTAATTCATGATTCTCA
TAACATTCAGCATAAGTGTAGCAAAGTTGCTAATAACGGAAGGGGATCATAGTGGTGTTGAATGTAACTTTGAAGTAGGGAATGGCCTTT
TAAGTCTGAGAGAGAACATTTGAATCCTTTTCAGGGATTTGTGTAGGGGTGTGTTTGTGTGTGTGTGTGAATGTGTGTGTGTGTAGATAA
GTGTATATACATAAATACACTCTTCTAAAGTTGTATATACATATGCACATTACATACATTTTAATTTATTGACAAAATTAACCAAATTAA
GATTTGGAGATGTGGGATGTTCTTGTTTTAAAATAGCATGTTTGAAACCATCAGTTTGTGTCTAAAATTAGCTGTAGCACATGGATGTTG
TCCATATTAAGCTATTTGCTGTTTGAATTATAGAGGTCTACAGTATTTGTGTTGGCATAGTTTTTGTAAAAAAAAGATTAAAAAATATCA
GGATGGTGGAAAAACTAGATCTGTGTATCTCTGTTTTGGCATGCATTTATTCAGTATCTTCTAGCAATGGTTTTTCTCTGTTGATCTACC
GTAGTATCCTATTTTTAAGTTTATTTTATTTTTAAGGAGTATTGTCATCACTTTTCAAGGTGTCTTGACTTCTACACAAAGTATATATAT
TCAGGACTTTAAAAAATAGCAGTACACATTTAACAGTAGCGAATTACACCAAAATGATTTACTTTGAGATTTGAATAATTTGCATAGCAG
TAAAATGTGTTTTGTGTAACATACAAATAGAAAAATGACCCAGTATCTTAATTGATACTTACTGGAGAGTATCAGAATTACCCAGCAGCT
CTTACAGAATGCCATAAATTCTTTAAGACTAAATATTGAAATCAATTATTTGAAGTAATGTTTCTGATTTACTGTTAAAAGTTGCTGAGC
TCAGTTTTTGGAGATATCATTTATGCCTGCCTGTTCCCTTATGACAGTGAGGCCTTCTTTGGCTCCACCTAGTATGATAATCATGGGTTC
TGTTTTAGTTGATGAGAAGTGGCTCCTATGAATGCCTCTGCTCAATTTCTTTTTATTTTACTTTATTTTATTTTTAGGGGTCTCGCCAAC
TCCTGGGCTCAAGTGATTCTCCTGCTTCCACCTCCCCACAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCTCTCTGTTCTTTTC
AGTGTCTCCGTGCCATCAGTCAGCAGTGCTTACATGTTTAGCATATTGTCATGCAGTTTCTCTTCTGTTCCCACGAGATATTTTTGGACA
AAAAATTGACAAAAGTACATGTGTTTTTCCCCACCTATCCCTTAGAAAACCTAATGTGTACTGCTATTTTTAAAACCAAAAAGAGACAGC
GTGACGATGCGTAAAGCATTTTTCTTAGCCTTTCCTTTGTCTTGATCTGTTAATGAGAACAAAACTGCCAGACTCAAAATACTCTACTAT
TGTGCTGAAAGAAATACAATTTAGATTGCACAAAATTTGAAAATATAACTCAGCTGTCTTTTAAAAGAGTTGTGTTGTTATCTACAAGAC
TATTAGCAGTCTTTTTTCAGAGCAAATTTTAACAGCTAGTTGTGAGTGGTTTAAAATATAGAAAATTATTAAAATCTTAGTTTGAGGGGT
TTTATAGTGGGAGAAAAAACAGGACCAAAGTTTATGTGCCTTCTTCAGTAGTCTTAATTGACCTTTTCTTCCTATTTGAGACTAAAGTAG
TATCAGTATTCTGGTTTTCAGGAAATATGTACTATATAGTTTTAAAAGAATGTTGTCCCACCAACTATTCATCCAAGCAAAGAATTGTAA
CTATAAATAAAGTCTCAGTTACACTTTTGCCTTTATCACATAATATTCATTGTAGAGCATTGTGCAGGTCCAAGAATAGAGCTGCTCAAA
ATCTTTGTGGTAGTTTCCTTAGTTTTTGTAACCTGAGGCATATGTTCCAGAGAACAGGGATATTTGTCTGGTCCAGTGACCTTGGTGATC
ATAGTCATAATTGAAAGATGCCTATGGCATGCTTAAATCAGCATTGTCAACTGATTTGTTGTTGTATTATTTTCACTTCTTGGATCTATG
TAGTAGTTGTAATAACAAATATTTAAATAGCTATTTTTTTGATGCCATTAAAAAAATCATACTCTGGCCTTTTTTCCCCCTTACTGTTGT
TTCCCAGATCTTTTAAAAATTCATCCCATATCCAGAAAGTACCAGTTATAAAGATTGCTGACCAAGCAAAGTTTTGCATCAAAGTGTCAC
CTCATTGCTCTGACCAAAGACTGACTGTTGTGGTTTTAACTCCTCTCTGTAAAGCATTTTGCATTTTCCCCAAGCTCCTTTCTGAAAGAA
GAACCAGTGCAGAGCGGCCTTTACTTTCAATTTCTACTGCTGAATAGACTACTTAGAGAAAATGTGAGTTTCAGTGTGAACAGAATGGAT
TAGGATGACGAGTTTGATGGGCATTTTCAGTACTGTATCTAAGAAAAAAAAAATAGCACAGCTAGGAGCCTCTGACATTGTCTGGTGTTT
TACGTGGTCTGTTCATCAAAATTCCCCTTTTCAGTTTTTAAGAATGTTCGTCTAACAGAAGAAAATGCTGTAAATATTTGTAACAACATT
TTTTTTAACAAGGCCAAAAAAGAAAAAAAGGTTTTTGGGAACAAATGAACTTATAAAGTGGTTTTATATAAAACATCAATTGTCTTGTAT
ATTTTGGATAAGCAGCAGTACCAGCTTTCATTTGTAACAGTCTGTGGCATTGGAAAAAAAGGAGTCTGTGATTGTTGAAGTGAATTATGT
TATAAATGCAAAGAGAAGATAAAATATTAAAAAACATATTTTCTAAATGCGTAGTGCATGGTTAATTCAAGCTTCTGTACACTACAGTAT
ATTCCATTTTCGTTCAGTTTGTATATTTGCTGACTATTACTTGATATCTCTAATCTCTTTTCCTAACAAATATAGCATTGTAGCATGCCT

>26862_26862_1_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374557_PTBP3_chr9_115060196_ENST00000334318_length(amino acids)=643AA_BP=102
MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVF
LLDGTEVSVDLPRGSDELLSSGIINGPFTMNSSTPSTGVYANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLL
MLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQS
PVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDK
SRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSV
LLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTK
DFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGE

--------------------------------------------------------------
>26862_26862_2_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374557_PTBP3_chr9_115060196_ENST00000458258_length(transcript)=7857nt_BP=824nt
GGAAAAGGCGCCTTGGGAGCGGGCGCTCGGCGGGGCCTCCTCGGGCCCCGGGCGCGGCGCGGCGAGTGGGAGCGAGCGCGCCAGGACCAC
GCAGGCGCCCTGCTCCGGCTGGCCCTCGGCCGGCGCGCGGCGCGGGAGCAGCCCGCAGCCCGCCTCCCGCGCCCCCGGCAGCCCCCTGGC
AGCCCGCAGCCGCCCGTCCGGAGCAGCCCCTCGGCAGCCCGCGCAGGCCGCCGGCCCGGGAGAGCGCGCGGCGGCGGCGGCGGCGGGACG
GCCCCGAGCGCGCCCTCCCGCCTGCGGCCACTCGCAGCCGGCGCTGGCCGGGCCGGCGCGCCCCGCAGGCGGCTAGAGCGCGGCCTCGGC
CTCGGCGCGGGCTTGCCCCGGGCCGTAGCCCGCGAGAGGCGGCGCGGGCGGCCGAGGGCACTGACGGCGTCGCGGGACGCTCCCGGGCGG
CGGCGCAGCGGCAGCGGCAGCGGCAGCGGCAGCGCAGGGGGCGGAGGCAGGGGGCGCCCCCAGCCAGGATGCTGCGGTTCCTGCGCCGGA
CCTTTGGCCGCCGCTCCATGCAGCGCTACGCGCGGGGCGCGGCGGGGCGCGGGGCCGCCGGGCTGGGGGACGAGCGCGATGGGGGGCCAC
GGGGGGGCCCGGCCGCCGCCGCCTCCTCCTCGGCGCTGCCCGCCGCGCCCGGGGGCAGCGTGTTCCCGGCGGGCGGCGGGCCCCTGCTCA
CCGGCGGCGCGGCCGTGCACATCTCCGCCGCCGGCGCCGCCAAGGCCACCCTCTACTGCCGCGTCTTCCTGCTCGACGGGACCGAAGTGA
GCGTGGACCTGCCGCGGGGATCTGATGAGCTTCTTTCTTCTGGCATCATTAACGGACCTTTTACCATGAATAGTTCTACTCCTTCTACAG
CTAATGGGAATGACAGCAAGAAATTTAAACGAGATAGACCTCCCTGTTCGCCTTCCCGTGTTCTCCATCTTCGAAAAATTCCATGTGATG
TCACCGAAGCAGAGATCATATCATTAGGTCTACCATTTGGCAAAGTAACTAATCTTTTGATGTTGAAAGGAAAAAGCCAGGCTTTCTTAG
AAATGGCTTCTGAGGAAGCTGCCGTTACTATGGTGAATTATTACACTCCTATTACTCCTCACCTTCGAAGCCAGCCTGTTTATATTCAGT
ATTCCAATCACAGAGAACTTAAGACTGACAATCTACCTAATCAAGCTCGAGCCCAAGCTGCACTGCAGGCTGTCAGTGCCGTCCAATCAG
GAAGCCTGGCCCTTTCTGGAGGTCCTTCCAATGAAGGCACAGTCCTACCTGGGCAGAGCCCTGTGCTTCGAATAATTATTGAAAACCTCT
TTTACCCTGTTACCCTGGAAGTTCTTCATCAGATATTTTCTAAATTTGGCACAGTCTTGAAGATTATCACCTTTACAAAGAATAATCAGT
TTCAAGCCTTGCTTCAGTATGCTGACCCAGTAAATGCACATTATGCCAAAATGGCTCTGGATGGCCAGAATATCTATAATGCATGCTGCA
CTCTGCGCATTGACTTCTCCAAGCTCACCAGCCTTAATGTGAAATATAATAATGACAAAAGCAGAGACTTCACTCGCTTAGACCTTCCTA
CTGGTGATGGCCAGCCATCCCTTGAACCCCCTATGGCTGCTGCTTTTGGTGCACCGGGTATAATTTCTTCACCATATGCAGGGGCTGCTG
GATTTGCCCCAGCCATTGGATTTCCTCAAGCTACAGGTCTATCAGTTCCAGCTGTTCCTGGAGCTCTTGGTCCTCTCACAATCACCTCTT
CTGCTGTCACTGGAAGGATGGCCATTCCTGGGGCTAGTGGTATACCAGGAAATTCTGTTCTACTCGTCACAAATCTCAATCCTGATCTTA
TCACACCACATGGGCTTTTTATCCTATTTGGAGTCTATGGTGATGTACATCGAGTGAAGATTATGTTTAATAAGAAAGAAAATGCCTTGG
TTCAGATGGCGGATGCAAATCAAGCTCAGCTAGCAATGAACCATCTAAGTGGTCAGAGACTTTATGGGAAAGTGCTTCGTGCTACACTGT
CCAAACATCAAGCAGTACAGCTTCCTCGAGAGGGACAAGAAGACCAAGGTCTGACTAAGGATTTCAGCAATAGTCCTTTGCATCGCTTTA
AAAAGCCGGGCTCTAAAAACTTCCAGAATATCTTTCCACCATCAGCCACTCTGCATCTTTCCAACATTCCCCCTTCTGTTACAGTGGATG
ATCTGAAGAACCTTTTCATAGAAGCTGGATGTTCAGTGAAGGCTTTTAAATTCTTTCAGAAAGATCGCAAAATGGCGCTCATTCAATTGG
GATCTGTGGAAGAAGCAATTCAGGCCCTCATTGAGCTTCATAACCATGACCTTGGAGAAAATCACCACCTCAGAGTTTCCTTCTCAAAAT
CTACAATCTGACTTTTCTGTGAATTTTTCTCCTAAAACTGGACCATAATTTCAGTAAAACCTTCAGACATAGACTGAAGCAGCTCAAGAC
CAATTTTGCCTCTTTCACAAAAATAACTCTGAGTTTGATATTCAAGTATATTTTAAAAATCAAGGGATTTTTTTTTTTTGTATTCCCCCT
GCCCCCGCCAGTCAAAGGTTTCTTTTCCCTTTTTACCATGGTTTCTACAAAAATAACCTTCAGGAAAAAGAAAATCAGGAAAAAAATTTT
TTTTCAATAATCTTATTCCCTATATTAAATTAGATTTGAAGAGGATTAACGTTGTTTTAGTTTGGGTCCAGATCAGCCTTATACAACATT
TCTAAACTCATTTGTACTTTTAAAAAATTTAAACACAGACTTCTAAAATTACTTGATGTAAGTAATTTAAATCACTTATGACCAAGTTAT
TAACCTTATGAATCAGAAGTCTGACCCTTGTAGGAAATTATATTCACATATAAAGTACATCAGATCTTTGCCATATATTGATGGTTATTA
TGCATAAACACATTGAGTTGTGTTGGAAGCAGATTTATAAACCTGCATGTTTTCTTTGAATGATTTCTTTTTTTCACTGTAAGACACTCC
TTTAAATAATGCCTATCTTTAACTTTTTAAGACTATTTGGAAAAATGCAGTGTCTCAGCTGTCCCCAGGGAAATTAAGTGGAATTCAACT
AAGATCTGTTAATAAGATGTCAGAATAACTAATAATTTTATTAGGAAAAAATCATGTTTTAAATTTCAAAATGACACTTATTTGTCAAGT
AATATGATCTTGGAAAATTTTAAAGAAAAATAATCCTACTTATAAACTACTTTTTTATAATTGTTTTCAGAAAAAAAGTTTACAGTCTTA
AGGAAAATATTCAGGTCTATCATATGGTTTGACAGATTTTTTAAAAGTTATTTTTGGTAAGGTCTTCTTTTAGAAAAAAATTAATCTCAA
GGGTTTTTTGTACCACTATAATCTCTAATACTTACTCAGAATTACTGTGTATTTACTTAATTTCTTATTATGTGCCTTATTATGTGCTTA
AGATACAATAGGTTAGAGTTTAATCTAAATATCTTGAAAGCTATATTGTGGGCTTGGTAAGCATTTTGTTTTTTCTTTCTCTGTTTTGGT
AAGGATTTAAAATTTTTTTCATTGCAATTTTAAGTGGTTTTCAATAAGTAATAGTTTTTATCAAATTTTTGGTGCTTGGTGCAGAGACGG
TGTGGGGAAGGGTGAATGGTTTTGGGAATAATTCAGTGCACACCTGTAGGCCTCTTTACATTGTGACTGATAGGGGTTATTGCATATCAA
TTTGGGGCTGTAGAGTGCAATCTCAGTTTCATCTTTTTCACCCATCAGAATTTGTCTCAGGATTACTTGGTTTTTCTCAGTCCTCAAGCG
AGAACTTGCTTTTCTTTGTTAATGTGACTTTCATTACTGAGTACCCACGTATTTGGAGTATGAGAAGGTGGGTTATTTCTCATACTCTGT
CCCTCTCTTTTTCATTGAATGTAAGAGTACATTTTAATGTTGCTTCAGTGATTGTATAATGTAAAATTGTTTCTTTTTAATAAGAAACTT
TGCTATTATTTCTTCAATTGTTGATCAGAATTTTTTAAAGCAGAATTTGTCAAAAGGGTCATTTTTTTGTCTACCCCTTTTACACTTTTC
AGATTCTCAAAGTGTCTCATCTCAACTTTTAAAAGAATAAAGAATATCTTGCTGGGCATGGTGGTGTGCGCCTGTGCGCCTGTAGTCCCA
GCTACAGGCTGAGCCTGTAGGCAGGAGGCTACAGGCAGGAGGATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGCGCTATGATCACATT
TGTGAATAGCCACTTCACTCCAGCCCTGGAACATAGTGTGACCCCTTCTCTTAAAAGTAAAAATTAAGAAAATCTCAATCTCTTTGCTGT
ATTCCAGTGATTAATTTGAACATAGGGAGGTTTTTACAGAAGAAATTTTACCAAAAAATAGAGACTGCAAGAGATGATACAGATTGTTTA
AAAAGCAGAATTCACTCACCACTGAGCAACACTTAGTTGGTAGAATAGAAAGGAGGGATACTAAGTTAAGACTTTTCAAATGGATCAGTT
TGGCTGAATAGATAGATATACTCATGTATGTAGTTGTGGGAGTTTTTAGTTTTTTGTTTTTTTACTTATGAAATAAGTTTTGACCTAGAC
ACAAGGGGTATATGAAGGAGGAAAAAAATTTCTTTGCAAAATCTCCCAAAACTTGCTTTTTTTTCCCTTCCACACAGGCACTATTATAAT
TTTCAGTGCCATGTTAAATTGGATTATTTCATTTACTTTAAGTTAGGAATTACTGTGTAATTTATTAATTCATGATTCTCATAACATTCA
GCATAAGTGTAGCAAAGTTGCTAATAACGGAAGGGGATCATAGTGGTGTTGAATGTAACTTTGAAGTAGGGAATGGCCTTTTAAGTCTGA
GAGAGAACATTTGAATCCTTTTCAGGGATTTGTGTAGGGGTGTGTTTGTGTGTGTGTGTGAATGTGTGTGTGTGTAGATAAGTGTATATA
CATAAATACACTCTTCTAAAGTTGTATATACATATGCACATTACATACATTTTAATTTATTGACAAAATTAACCAAATTAAGATTTGGAG
ATGTGGGATGTTCTTGTTTTAAAATAGCATGTTTGAAACCATCAGTTTGTGTCTAAAATTAGCTGTAGCACATGGATGTTGTCCATATTA
AGCTATTTGCTGTTTGAATTATAGAGGTCTACAGTATTTGTGTTGGCATAGTTTTTGTAAAAAAAAGATTAAAAAATATCAGGATGGTGG
AAAAACTAGATCTGTGTATCTCTGTTTTGGCATGCATTTATTCAGTATCTTCTAGCAATGGTTTTTCTCTGTTGATCTACCGTAGTATCC
TATTTTTAAGTTTATTTTATTTTTAAGGAGTATTGTCATCACTTTTCAAGGTGTCTTGACTTCTACACAAAGTATATATATTCAGGACTT
TAAAAAATAGCAGTACACATTTAACAGTAGCGAATTACACCAAAATGATTTACTTTGAGATTTGAATAATTTGCATAGCAGTAAAATGTG
TTTTGTGTAACATACAAATAGAAAAATGACCCAGTATCTTAATTGATACTTACTGGAGAGTATCAGAATTACCCAGCAGCTCTTACAGAA
TGCCATAAATTCTTTAAGACTAAATATTGAAATCAATTATTTGAAGTAATGTTTCTGATTTACTGTTAAAAGTTGCTGAGCTCAGTTTTT
GGAGATATCATTTATGCCTGCCTGTTCCCTTATGACAGTGAGGCCTTCTTTGGCTCCACCTAGTATGATAATCATGGGTTCTGTTTTAGT
TGATGAGAAGTGGCTCCTATGAATGCCTCTGCTCAATTTCTTTTTATTTTACTTTATTTTATTTTTAGGGGTCTCGCCAACTCCTGGGCT
CAAGTGATTCTCCTGCTTCCACCTCCCCACAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCTCTCTGTTCTTTTCAGTGTCTCC
GTGCCATCAGTCAGCAGTGCTTACATGTTTAGCATATTGTCATGCAGTTTCTCTTCTGTTCCCACGAGATATTTTTGGACAAAAAATTGA
CAAAAGTACATGTGTTTTTCCCCACCTATCCCTTAGAAAACCTAATGTGTACTGCTATTTTTAAAACCAAAAAGAGACAGCGTGACGATG
CGTAAAGCATTTTTCTTAGCCTTTCCTTTGTCTTGATCTGTTAATGAGAACAAAACTGCCAGACTCAAAATACTCTACTATTGTGCTGAA
AGAAATACAATTTAGATTGCACAAAATTTGAAAATATAACTCAGCTGTCTTTTAAAAGAGTTGTGTTGTTATCTACAAGACTATTAGCAG
TCTTTTTTCAGAGCAAATTTTAACAGCTAGTTGTGAGTGGTTTAAAATATAGAAAATTATTAAAATCTTAGTTTGAGGGGTTTTATAGTG
GGAGAAAAAACAGGACCAAAGTTTATGTGCCTTCTTCAGTAGTCTTAATTGACCTTTTCTTCCTATTTGAGACTAAAGTAGTATCAGTAT
TCTGGTTTTCAGGAAATATGTACTATATAGTTTTAAAAGAATGTTGTCCCACCAACTATTCATCCAAGCAAAGAATTGTAACTATAAATA
AAGTCTCAGTTACACTTTTGCCTTTATCACATAATATTCATTGTAGAGCATTGTGCAGGTCCAAGAATAGAGCTGCTCAAAATCTTTGTG
GTAGTTTCCTTAGTTTTTGTAACCTGAGGCATATGTTCCAGAGAACAGGGATATTTGTCTGGTCCAGTGACCTTGGTGATCATAGTCATA
ATTGAAAGATGCCTATGGCATGCTTAAATCAGCATTGTCAACTGATTTGTTGTTGTATTATTTTCACTTCTTGGATCTATGTAGTAGTTG
TAATAACAAATATTTAAATAGCTATTTTTTTGATGCCATTAAAAAAATCATACTCTGGCCTTTTTTCCCCCTTACTGTTGTTTCCCAGAT
CTTTTAAAAATTCATCCCATATCCAGAAAGTACCAGTTATAAAGATTGCTGACCAAGCAAAGTTTTGCATCAAAGTGTCACCTCATTGCT
CTGACCAAAGACTGACTGTTGTGGTTTTAACTCCTCTCTGTAAAGCATTTTGCATTTTCCCCAAGCTCCTTTCTGAAAGAAGAACCAGTG
CAGAGCGGCCTTTACTTTCAATTTCTACTGCTGAATAGACTACTTAGAGAAAATGTGAGTTTCAGTGTGAACAGAATGGATTAGGATGAC
GAGTTTGATGGGCATTTTCAGTACTGTATCTAAGAAAAAAAAAATAGCACAGCTAGGAGCCTCTGACATTGTCTGGTGTTTTACGTGGTC
TGTTCATCAAAATTCCCCTTTTCAGTTTTTAAGAATGTTCGTCTAACAGAAGAAAATGCTGTAAATATTTGTAACAACATTTTTTTTAAC
AAGGCCAAAAAAGAAAAAAAGGTTTTTGGGAACAAATGAACTTATAAAGTGGTTTTATATAAAACATCAATTGTCTTGTATATTTTGGAT
AAGCAGCAGTACCAGCTTTCATTTGTAACAGTCTGTGGCATTGGAAAAAAAGGAGTCTGTGATTGTTGAAGTGAATTATGTTATAAATGC
AAAGAGAAGATAAAATATTAAAAAACATATTTTCTAAATGCGTAGTGCATGGTTAATTCAAGCTTCTGTACACTACAGTATATTCCATTT
TCGTTCAGTTTGTATATTTGCTGACTATTACTTGATATCTCTAATCTCTTTTCCTAACAAATATAGCATTGTAGCATGCCTTTTAATAAA

>26862_26862_2_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374557_PTBP3_chr9_115060196_ENST00000458258_length(amino acids)=640AA_BP=102
MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVF
LLDGTEVSVDLPRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLK
GKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVL
RIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRD
FTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLV
TNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFS
NSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHH

--------------------------------------------------------------
>26862_26862_3_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374566_PTBP3_chr9_115060196_ENST00000334318_length(transcript)=7866nt_BP=824nt
GGAAAAGGCGCCTTGGGAGCGGGCGCTCGGCGGGGCCTCCTCGGGCCCCGGGCGCGGCGCGGCGAGTGGGAGCGAGCGCGCCAGGACCAC
GCAGGCGCCCTGCTCCGGCTGGCCCTCGGCCGGCGCGCGGCGCGGGAGCAGCCCGCAGCCCGCCTCCCGCGCCCCCGGCAGCCCCCTGGC
AGCCCGCAGCCGCCCGTCCGGAGCAGCCCCTCGGCAGCCCGCGCAGGCCGCCGGCCCGGGAGAGCGCGCGGCGGCGGCGGCGGCGGGACG
GCCCCGAGCGCGCCCTCCCGCCTGCGGCCACTCGCAGCCGGCGCTGGCCGGGCCGGCGCGCCCCGCAGGCGGCTAGAGCGCGGCCTCGGC
CTCGGCGCGGGCTTGCCCCGGGCCGTAGCCCGCGAGAGGCGGCGCGGGCGGCCGAGGGCACTGACGGCGTCGCGGGACGCTCCCGGGCGG
CGGCGCAGCGGCAGCGGCAGCGGCAGCGGCAGCGCAGGGGGCGGAGGCAGGGGGCGCCCCCAGCCAGGATGCTGCGGTTCCTGCGCCGGA
CCTTTGGCCGCCGCTCCATGCAGCGCTACGCGCGGGGCGCGGCGGGGCGCGGGGCCGCCGGGCTGGGGGACGAGCGCGATGGGGGGCCAC
GGGGGGGCCCGGCCGCCGCCGCCTCCTCCTCGGCGCTGCCCGCCGCGCCCGGGGGCAGCGTGTTCCCGGCGGGCGGCGGGCCCCTGCTCA
CCGGCGGCGCGGCCGTGCACATCTCCGCCGCCGGCGCCGCCAAGGCCACCCTCTACTGCCGCGTCTTCCTGCTCGACGGGACCGAAGTGA
GCGTGGACCTGCCGCGGGGATCTGATGAGCTTCTTTCTTCTGGCATCATTAACGGACCTTTTACCATGAATAGTTCTACTCCTTCTACAG
GTGTGTATGCTAATGGGAATGACAGCAAGAAATTTAAACGAGATAGACCTCCCTGTTCGCCTTCCCGTGTTCTCCATCTTCGAAAAATTC
CATGTGATGTCACCGAAGCAGAGATCATATCATTAGGTCTACCATTTGGCAAAGTAACTAATCTTTTGATGTTGAAAGGAAAAAGCCAGG
CTTTCTTAGAAATGGCTTCTGAGGAAGCTGCCGTTACTATGGTGAATTATTACACTCCTATTACTCCTCACCTTCGAAGCCAGCCTGTTT
ATATTCAGTATTCCAATCACAGAGAACTTAAGACTGACAATCTACCTAATCAAGCTCGAGCCCAAGCTGCACTGCAGGCTGTCAGTGCCG
TCCAATCAGGAAGCCTGGCCCTTTCTGGAGGTCCTTCCAATGAAGGCACAGTCCTACCTGGGCAGAGCCCTGTGCTTCGAATAATTATTG
AAAACCTCTTTTACCCTGTTACCCTGGAAGTTCTTCATCAGATATTTTCTAAATTTGGCACAGTCTTGAAGATTATCACCTTTACAAAGA
ATAATCAGTTTCAAGCCTTGCTTCAGTATGCTGACCCAGTAAATGCACATTATGCCAAAATGGCTCTGGATGGCCAGAATATCTATAATG
CATGCTGCACTCTGCGCATTGACTTCTCCAAGCTCACCAGCCTTAATGTGAAATATAATAATGACAAAAGCAGAGACTTCACTCGCTTAG
ACCTTCCTACTGGTGATGGCCAGCCATCCCTTGAACCCCCTATGGCTGCTGCTTTTGGTGCACCGGGTATAATTTCTTCACCATATGCAG
GGGCTGCTGGATTTGCCCCAGCCATTGGATTTCCTCAAGCTACAGGTCTATCAGTTCCAGCTGTTCCTGGAGCTCTTGGTCCTCTCACAA
TCACCTCTTCTGCTGTCACTGGAAGGATGGCCATTCCTGGGGCTAGTGGTATACCAGGAAATTCTGTTCTACTCGTCACAAATCTCAATC
CTGATCTTATCACACCACATGGGCTTTTTATCCTATTTGGAGTCTATGGTGATGTACATCGAGTGAAGATTATGTTTAATAAGAAAGAAA
ATGCCTTGGTTCAGATGGCGGATGCAAATCAAGCTCAGCTAGCAATGAACCATCTAAGTGGTCAGAGACTTTATGGGAAAGTGCTTCGTG
CTACACTGTCCAAACATCAAGCAGTACAGCTTCCTCGAGAGGGACAAGAAGACCAAGGTCTGACTAAGGATTTCAGCAATAGTCCTTTGC
ATCGCTTTAAAAAGCCGGGCTCTAAAAACTTCCAGAATATCTTTCCACCATCAGCCACTCTGCATCTTTCCAACATTCCCCCTTCTGTTA
CAGTGGATGATCTGAAGAACCTTTTCATAGAAGCTGGATGTTCAGTGAAGGCTTTTAAATTCTTTCAGAAAGATCGCAAAATGGCGCTCA
TTCAATTGGGATCTGTGGAAGAAGCAATTCAGGCCCTCATTGAGCTTCATAACCATGACCTTGGAGAAAATCACCACCTCAGAGTTTCCT
TCTCAAAATCTACAATCTGACTTTTCTGTGAATTTTTCTCCTAAAACTGGACCATAATTTCAGTAAAACCTTCAGACATAGACTGAAGCA
GCTCAAGACCAATTTTGCCTCTTTCACAAAAATAACTCTGAGTTTGATATTCAAGTATATTTTAAAAATCAAGGGATTTTTTTTTTTTGT
ATTCCCCCTGCCCCCGCCAGTCAAAGGTTTCTTTTCCCTTTTTACCATGGTTTCTACAAAAATAACCTTCAGGAAAAAGAAAATCAGGAA
AAAAATTTTTTTTCAATAATCTTATTCCCTATATTAAATTAGATTTGAAGAGGATTAACGTTGTTTTAGTTTGGGTCCAGATCAGCCTTA
TACAACATTTCTAAACTCATTTGTACTTTTAAAAAATTTAAACACAGACTTCTAAAATTACTTGATGTAAGTAATTTAAATCACTTATGA
CCAAGTTATTAACCTTATGAATCAGAAGTCTGACCCTTGTAGGAAATTATATTCACATATAAAGTACATCAGATCTTTGCCATATATTGA
TGGTTATTATGCATAAACACATTGAGTTGTGTTGGAAGCAGATTTATAAACCTGCATGTTTTCTTTGAATGATTTCTTTTTTTCACTGTA
AGACACTCCTTTAAATAATGCCTATCTTTAACTTTTTAAGACTATTTGGAAAAATGCAGTGTCTCAGCTGTCCCCAGGGAAATTAAGTGG
AATTCAACTAAGATCTGTTAATAAGATGTCAGAATAACTAATAATTTTATTAGGAAAAAATCATGTTTTAAATTTCAAAATGACACTTAT
TTGTCAAGTAATATGATCTTGGAAAATTTTAAAGAAAAATAATCCTACTTATAAACTACTTTTTTATAATTGTTTTCAGAAAAAAAGTTT
ACAGTCTTAAGGAAAATATTCAGGTCTATCATATGGTTTGACAGATTTTTTAAAAGTTATTTTTGGTAAGGTCTTCTTTTAGAAAAAAAT
TAATCTCAAGGGTTTTTTGTACCACTATAATCTCTAATACTTACTCAGAATTACTGTGTATTTACTTAATTTCTTATTATGTGCCTTATT
ATGTGCTTAAGATACAATAGGTTAGAGTTTAATCTAAATATCTTGAAAGCTATATTGTGGGCTTGGTAAGCATTTTGTTTTTTCTTTCTC
TGTTTTGGTAAGGATTTAAAATTTTTTTCATTGCAATTTTAAGTGGTTTTCAATAAGTAATAGTTTTTATCAAATTTTTGGTGCTTGGTG
CAGAGACGGTGTGGGGAAGGGTGAATGGTTTTGGGAATAATTCAGTGCACACCTGTAGGCCTCTTTACATTGTGACTGATAGGGGTTATT
GCATATCAATTTGGGGCTGTAGAGTGCAATCTCAGTTTCATCTTTTTCACCCATCAGAATTTGTCTCAGGATTACTTGGTTTTTCTCAGT
CCTCAAGCGAGAACTTGCTTTTCTTTGTTAATGTGACTTTCATTACTGAGTACCCACGTATTTGGAGTATGAGAAGGTGGGTTATTTCTC
ATACTCTGTCCCTCTCTTTTTCATTGAATGTAAGAGTACATTTTAATGTTGCTTCAGTGATTGTATAATGTAAAATTGTTTCTTTTTAAT
AAGAAACTTTGCTATTATTTCTTCAATTGTTGATCAGAATTTTTTAAAGCAGAATTTGTCAAAAGGGTCATTTTTTTGTCTACCCCTTTT
ACACTTTTCAGATTCTCAAAGTGTCTCATCTCAACTTTTAAAAGAATAAAGAATATCTTGCTGGGCATGGTGGTGTGCGCCTGTGCGCCT
GTAGTCCCAGCTACAGGCTGAGCCTGTAGGCAGGAGGCTACAGGCAGGAGGATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGCGCTAT
GATCACATTTGTGAATAGCCACTTCACTCCAGCCCTGGAACATAGTGTGACCCCTTCTCTTAAAAGTAAAAATTAAGAAAATCTCAATCT
CTTTGCTGTATTCCAGTGATTAATTTGAACATAGGGAGGTTTTTACAGAAGAAATTTTACCAAAAAATAGAGACTGCAAGAGATGATACA
GATTGTTTAAAAAGCAGAATTCACTCACCACTGAGCAACACTTAGTTGGTAGAATAGAAAGGAGGGATACTAAGTTAAGACTTTTCAAAT
GGATCAGTTTGGCTGAATAGATAGATATACTCATGTATGTAGTTGTGGGAGTTTTTAGTTTTTTGTTTTTTTACTTATGAAATAAGTTTT
GACCTAGACACAAGGGGTATATGAAGGAGGAAAAAAATTTCTTTGCAAAATCTCCCAAAACTTGCTTTTTTTTCCCTTCCACACAGGCAC
TATTATAATTTTCAGTGCCATGTTAAATTGGATTATTTCATTTACTTTAAGTTAGGAATTACTGTGTAATTTATTAATTCATGATTCTCA
TAACATTCAGCATAAGTGTAGCAAAGTTGCTAATAACGGAAGGGGATCATAGTGGTGTTGAATGTAACTTTGAAGTAGGGAATGGCCTTT
TAAGTCTGAGAGAGAACATTTGAATCCTTTTCAGGGATTTGTGTAGGGGTGTGTTTGTGTGTGTGTGTGAATGTGTGTGTGTGTAGATAA
GTGTATATACATAAATACACTCTTCTAAAGTTGTATATACATATGCACATTACATACATTTTAATTTATTGACAAAATTAACCAAATTAA
GATTTGGAGATGTGGGATGTTCTTGTTTTAAAATAGCATGTTTGAAACCATCAGTTTGTGTCTAAAATTAGCTGTAGCACATGGATGTTG
TCCATATTAAGCTATTTGCTGTTTGAATTATAGAGGTCTACAGTATTTGTGTTGGCATAGTTTTTGTAAAAAAAAGATTAAAAAATATCA
GGATGGTGGAAAAACTAGATCTGTGTATCTCTGTTTTGGCATGCATTTATTCAGTATCTTCTAGCAATGGTTTTTCTCTGTTGATCTACC
GTAGTATCCTATTTTTAAGTTTATTTTATTTTTAAGGAGTATTGTCATCACTTTTCAAGGTGTCTTGACTTCTACACAAAGTATATATAT
TCAGGACTTTAAAAAATAGCAGTACACATTTAACAGTAGCGAATTACACCAAAATGATTTACTTTGAGATTTGAATAATTTGCATAGCAG
TAAAATGTGTTTTGTGTAACATACAAATAGAAAAATGACCCAGTATCTTAATTGATACTTACTGGAGAGTATCAGAATTACCCAGCAGCT
CTTACAGAATGCCATAAATTCTTTAAGACTAAATATTGAAATCAATTATTTGAAGTAATGTTTCTGATTTACTGTTAAAAGTTGCTGAGC
TCAGTTTTTGGAGATATCATTTATGCCTGCCTGTTCCCTTATGACAGTGAGGCCTTCTTTGGCTCCACCTAGTATGATAATCATGGGTTC
TGTTTTAGTTGATGAGAAGTGGCTCCTATGAATGCCTCTGCTCAATTTCTTTTTATTTTACTTTATTTTATTTTTAGGGGTCTCGCCAAC
TCCTGGGCTCAAGTGATTCTCCTGCTTCCACCTCCCCACAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCTCTCTGTTCTTTTC
AGTGTCTCCGTGCCATCAGTCAGCAGTGCTTACATGTTTAGCATATTGTCATGCAGTTTCTCTTCTGTTCCCACGAGATATTTTTGGACA
AAAAATTGACAAAAGTACATGTGTTTTTCCCCACCTATCCCTTAGAAAACCTAATGTGTACTGCTATTTTTAAAACCAAAAAGAGACAGC
GTGACGATGCGTAAAGCATTTTTCTTAGCCTTTCCTTTGTCTTGATCTGTTAATGAGAACAAAACTGCCAGACTCAAAATACTCTACTAT
TGTGCTGAAAGAAATACAATTTAGATTGCACAAAATTTGAAAATATAACTCAGCTGTCTTTTAAAAGAGTTGTGTTGTTATCTACAAGAC
TATTAGCAGTCTTTTTTCAGAGCAAATTTTAACAGCTAGTTGTGAGTGGTTTAAAATATAGAAAATTATTAAAATCTTAGTTTGAGGGGT
TTTATAGTGGGAGAAAAAACAGGACCAAAGTTTATGTGCCTTCTTCAGTAGTCTTAATTGACCTTTTCTTCCTATTTGAGACTAAAGTAG
TATCAGTATTCTGGTTTTCAGGAAATATGTACTATATAGTTTTAAAAGAATGTTGTCCCACCAACTATTCATCCAAGCAAAGAATTGTAA
CTATAAATAAAGTCTCAGTTACACTTTTGCCTTTATCACATAATATTCATTGTAGAGCATTGTGCAGGTCCAAGAATAGAGCTGCTCAAA
ATCTTTGTGGTAGTTTCCTTAGTTTTTGTAACCTGAGGCATATGTTCCAGAGAACAGGGATATTTGTCTGGTCCAGTGACCTTGGTGATC
ATAGTCATAATTGAAAGATGCCTATGGCATGCTTAAATCAGCATTGTCAACTGATTTGTTGTTGTATTATTTTCACTTCTTGGATCTATG
TAGTAGTTGTAATAACAAATATTTAAATAGCTATTTTTTTGATGCCATTAAAAAAATCATACTCTGGCCTTTTTTCCCCCTTACTGTTGT
TTCCCAGATCTTTTAAAAATTCATCCCATATCCAGAAAGTACCAGTTATAAAGATTGCTGACCAAGCAAAGTTTTGCATCAAAGTGTCAC
CTCATTGCTCTGACCAAAGACTGACTGTTGTGGTTTTAACTCCTCTCTGTAAAGCATTTTGCATTTTCCCCAAGCTCCTTTCTGAAAGAA
GAACCAGTGCAGAGCGGCCTTTACTTTCAATTTCTACTGCTGAATAGACTACTTAGAGAAAATGTGAGTTTCAGTGTGAACAGAATGGAT
TAGGATGACGAGTTTGATGGGCATTTTCAGTACTGTATCTAAGAAAAAAAAAATAGCACAGCTAGGAGCCTCTGACATTGTCTGGTGTTT
TACGTGGTCTGTTCATCAAAATTCCCCTTTTCAGTTTTTAAGAATGTTCGTCTAACAGAAGAAAATGCTGTAAATATTTGTAACAACATT
TTTTTTAACAAGGCCAAAAAAGAAAAAAAGGTTTTTGGGAACAAATGAACTTATAAAGTGGTTTTATATAAAACATCAATTGTCTTGTAT
ATTTTGGATAAGCAGCAGTACCAGCTTTCATTTGTAACAGTCTGTGGCATTGGAAAAAAAGGAGTCTGTGATTGTTGAAGTGAATTATGT
TATAAATGCAAAGAGAAGATAAAATATTAAAAAACATATTTTCTAAATGCGTAGTGCATGGTTAATTCAAGCTTCTGTACACTACAGTAT
ATTCCATTTTCGTTCAGTTTGTATATTTGCTGACTATTACTTGATATCTCTAATCTCTTTTCCTAACAAATATAGCATTGTAGCATGCCT

>26862_26862_3_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374566_PTBP3_chr9_115060196_ENST00000334318_length(amino acids)=643AA_BP=102
MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVF
LLDGTEVSVDLPRGSDELLSSGIINGPFTMNSSTPSTGVYANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLL
MLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQS
PVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDK
SRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSV
LLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTK
DFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGE

--------------------------------------------------------------
>26862_26862_4_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374566_PTBP3_chr9_115060196_ENST00000458258_length(transcript)=7857nt_BP=824nt
GGAAAAGGCGCCTTGGGAGCGGGCGCTCGGCGGGGCCTCCTCGGGCCCCGGGCGCGGCGCGGCGAGTGGGAGCGAGCGCGCCAGGACCAC
GCAGGCGCCCTGCTCCGGCTGGCCCTCGGCCGGCGCGCGGCGCGGGAGCAGCCCGCAGCCCGCCTCCCGCGCCCCCGGCAGCCCCCTGGC
AGCCCGCAGCCGCCCGTCCGGAGCAGCCCCTCGGCAGCCCGCGCAGGCCGCCGGCCCGGGAGAGCGCGCGGCGGCGGCGGCGGCGGGACG
GCCCCGAGCGCGCCCTCCCGCCTGCGGCCACTCGCAGCCGGCGCTGGCCGGGCCGGCGCGCCCCGCAGGCGGCTAGAGCGCGGCCTCGGC
CTCGGCGCGGGCTTGCCCCGGGCCGTAGCCCGCGAGAGGCGGCGCGGGCGGCCGAGGGCACTGACGGCGTCGCGGGACGCTCCCGGGCGG
CGGCGCAGCGGCAGCGGCAGCGGCAGCGGCAGCGCAGGGGGCGGAGGCAGGGGGCGCCCCCAGCCAGGATGCTGCGGTTCCTGCGCCGGA
CCTTTGGCCGCCGCTCCATGCAGCGCTACGCGCGGGGCGCGGCGGGGCGCGGGGCCGCCGGGCTGGGGGACGAGCGCGATGGGGGGCCAC
GGGGGGGCCCGGCCGCCGCCGCCTCCTCCTCGGCGCTGCCCGCCGCGCCCGGGGGCAGCGTGTTCCCGGCGGGCGGCGGGCCCCTGCTCA
CCGGCGGCGCGGCCGTGCACATCTCCGCCGCCGGCGCCGCCAAGGCCACCCTCTACTGCCGCGTCTTCCTGCTCGACGGGACCGAAGTGA
GCGTGGACCTGCCGCGGGGATCTGATGAGCTTCTTTCTTCTGGCATCATTAACGGACCTTTTACCATGAATAGTTCTACTCCTTCTACAG
CTAATGGGAATGACAGCAAGAAATTTAAACGAGATAGACCTCCCTGTTCGCCTTCCCGTGTTCTCCATCTTCGAAAAATTCCATGTGATG
TCACCGAAGCAGAGATCATATCATTAGGTCTACCATTTGGCAAAGTAACTAATCTTTTGATGTTGAAAGGAAAAAGCCAGGCTTTCTTAG
AAATGGCTTCTGAGGAAGCTGCCGTTACTATGGTGAATTATTACACTCCTATTACTCCTCACCTTCGAAGCCAGCCTGTTTATATTCAGT
ATTCCAATCACAGAGAACTTAAGACTGACAATCTACCTAATCAAGCTCGAGCCCAAGCTGCACTGCAGGCTGTCAGTGCCGTCCAATCAG
GAAGCCTGGCCCTTTCTGGAGGTCCTTCCAATGAAGGCACAGTCCTACCTGGGCAGAGCCCTGTGCTTCGAATAATTATTGAAAACCTCT
TTTACCCTGTTACCCTGGAAGTTCTTCATCAGATATTTTCTAAATTTGGCACAGTCTTGAAGATTATCACCTTTACAAAGAATAATCAGT
TTCAAGCCTTGCTTCAGTATGCTGACCCAGTAAATGCACATTATGCCAAAATGGCTCTGGATGGCCAGAATATCTATAATGCATGCTGCA
CTCTGCGCATTGACTTCTCCAAGCTCACCAGCCTTAATGTGAAATATAATAATGACAAAAGCAGAGACTTCACTCGCTTAGACCTTCCTA
CTGGTGATGGCCAGCCATCCCTTGAACCCCCTATGGCTGCTGCTTTTGGTGCACCGGGTATAATTTCTTCACCATATGCAGGGGCTGCTG
GATTTGCCCCAGCCATTGGATTTCCTCAAGCTACAGGTCTATCAGTTCCAGCTGTTCCTGGAGCTCTTGGTCCTCTCACAATCACCTCTT
CTGCTGTCACTGGAAGGATGGCCATTCCTGGGGCTAGTGGTATACCAGGAAATTCTGTTCTACTCGTCACAAATCTCAATCCTGATCTTA
TCACACCACATGGGCTTTTTATCCTATTTGGAGTCTATGGTGATGTACATCGAGTGAAGATTATGTTTAATAAGAAAGAAAATGCCTTGG
TTCAGATGGCGGATGCAAATCAAGCTCAGCTAGCAATGAACCATCTAAGTGGTCAGAGACTTTATGGGAAAGTGCTTCGTGCTACACTGT
CCAAACATCAAGCAGTACAGCTTCCTCGAGAGGGACAAGAAGACCAAGGTCTGACTAAGGATTTCAGCAATAGTCCTTTGCATCGCTTTA
AAAAGCCGGGCTCTAAAAACTTCCAGAATATCTTTCCACCATCAGCCACTCTGCATCTTTCCAACATTCCCCCTTCTGTTACAGTGGATG
ATCTGAAGAACCTTTTCATAGAAGCTGGATGTTCAGTGAAGGCTTTTAAATTCTTTCAGAAAGATCGCAAAATGGCGCTCATTCAATTGG
GATCTGTGGAAGAAGCAATTCAGGCCCTCATTGAGCTTCATAACCATGACCTTGGAGAAAATCACCACCTCAGAGTTTCCTTCTCAAAAT
CTACAATCTGACTTTTCTGTGAATTTTTCTCCTAAAACTGGACCATAATTTCAGTAAAACCTTCAGACATAGACTGAAGCAGCTCAAGAC
CAATTTTGCCTCTTTCACAAAAATAACTCTGAGTTTGATATTCAAGTATATTTTAAAAATCAAGGGATTTTTTTTTTTTGTATTCCCCCT
GCCCCCGCCAGTCAAAGGTTTCTTTTCCCTTTTTACCATGGTTTCTACAAAAATAACCTTCAGGAAAAAGAAAATCAGGAAAAAAATTTT
TTTTCAATAATCTTATTCCCTATATTAAATTAGATTTGAAGAGGATTAACGTTGTTTTAGTTTGGGTCCAGATCAGCCTTATACAACATT
TCTAAACTCATTTGTACTTTTAAAAAATTTAAACACAGACTTCTAAAATTACTTGATGTAAGTAATTTAAATCACTTATGACCAAGTTAT
TAACCTTATGAATCAGAAGTCTGACCCTTGTAGGAAATTATATTCACATATAAAGTACATCAGATCTTTGCCATATATTGATGGTTATTA
TGCATAAACACATTGAGTTGTGTTGGAAGCAGATTTATAAACCTGCATGTTTTCTTTGAATGATTTCTTTTTTTCACTGTAAGACACTCC
TTTAAATAATGCCTATCTTTAACTTTTTAAGACTATTTGGAAAAATGCAGTGTCTCAGCTGTCCCCAGGGAAATTAAGTGGAATTCAACT
AAGATCTGTTAATAAGATGTCAGAATAACTAATAATTTTATTAGGAAAAAATCATGTTTTAAATTTCAAAATGACACTTATTTGTCAAGT
AATATGATCTTGGAAAATTTTAAAGAAAAATAATCCTACTTATAAACTACTTTTTTATAATTGTTTTCAGAAAAAAAGTTTACAGTCTTA
AGGAAAATATTCAGGTCTATCATATGGTTTGACAGATTTTTTAAAAGTTATTTTTGGTAAGGTCTTCTTTTAGAAAAAAATTAATCTCAA
GGGTTTTTTGTACCACTATAATCTCTAATACTTACTCAGAATTACTGTGTATTTACTTAATTTCTTATTATGTGCCTTATTATGTGCTTA
AGATACAATAGGTTAGAGTTTAATCTAAATATCTTGAAAGCTATATTGTGGGCTTGGTAAGCATTTTGTTTTTTCTTTCTCTGTTTTGGT
AAGGATTTAAAATTTTTTTCATTGCAATTTTAAGTGGTTTTCAATAAGTAATAGTTTTTATCAAATTTTTGGTGCTTGGTGCAGAGACGG
TGTGGGGAAGGGTGAATGGTTTTGGGAATAATTCAGTGCACACCTGTAGGCCTCTTTACATTGTGACTGATAGGGGTTATTGCATATCAA
TTTGGGGCTGTAGAGTGCAATCTCAGTTTCATCTTTTTCACCCATCAGAATTTGTCTCAGGATTACTTGGTTTTTCTCAGTCCTCAAGCG
AGAACTTGCTTTTCTTTGTTAATGTGACTTTCATTACTGAGTACCCACGTATTTGGAGTATGAGAAGGTGGGTTATTTCTCATACTCTGT
CCCTCTCTTTTTCATTGAATGTAAGAGTACATTTTAATGTTGCTTCAGTGATTGTATAATGTAAAATTGTTTCTTTTTAATAAGAAACTT
TGCTATTATTTCTTCAATTGTTGATCAGAATTTTTTAAAGCAGAATTTGTCAAAAGGGTCATTTTTTTGTCTACCCCTTTTACACTTTTC
AGATTCTCAAAGTGTCTCATCTCAACTTTTAAAAGAATAAAGAATATCTTGCTGGGCATGGTGGTGTGCGCCTGTGCGCCTGTAGTCCCA
GCTACAGGCTGAGCCTGTAGGCAGGAGGCTACAGGCAGGAGGATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGCGCTATGATCACATT
TGTGAATAGCCACTTCACTCCAGCCCTGGAACATAGTGTGACCCCTTCTCTTAAAAGTAAAAATTAAGAAAATCTCAATCTCTTTGCTGT
ATTCCAGTGATTAATTTGAACATAGGGAGGTTTTTACAGAAGAAATTTTACCAAAAAATAGAGACTGCAAGAGATGATACAGATTGTTTA
AAAAGCAGAATTCACTCACCACTGAGCAACACTTAGTTGGTAGAATAGAAAGGAGGGATACTAAGTTAAGACTTTTCAAATGGATCAGTT
TGGCTGAATAGATAGATATACTCATGTATGTAGTTGTGGGAGTTTTTAGTTTTTTGTTTTTTTACTTATGAAATAAGTTTTGACCTAGAC
ACAAGGGGTATATGAAGGAGGAAAAAAATTTCTTTGCAAAATCTCCCAAAACTTGCTTTTTTTTCCCTTCCACACAGGCACTATTATAAT
TTTCAGTGCCATGTTAAATTGGATTATTTCATTTACTTTAAGTTAGGAATTACTGTGTAATTTATTAATTCATGATTCTCATAACATTCA
GCATAAGTGTAGCAAAGTTGCTAATAACGGAAGGGGATCATAGTGGTGTTGAATGTAACTTTGAAGTAGGGAATGGCCTTTTAAGTCTGA
GAGAGAACATTTGAATCCTTTTCAGGGATTTGTGTAGGGGTGTGTTTGTGTGTGTGTGTGAATGTGTGTGTGTGTAGATAAGTGTATATA
CATAAATACACTCTTCTAAAGTTGTATATACATATGCACATTACATACATTTTAATTTATTGACAAAATTAACCAAATTAAGATTTGGAG
ATGTGGGATGTTCTTGTTTTAAAATAGCATGTTTGAAACCATCAGTTTGTGTCTAAAATTAGCTGTAGCACATGGATGTTGTCCATATTA
AGCTATTTGCTGTTTGAATTATAGAGGTCTACAGTATTTGTGTTGGCATAGTTTTTGTAAAAAAAAGATTAAAAAATATCAGGATGGTGG
AAAAACTAGATCTGTGTATCTCTGTTTTGGCATGCATTTATTCAGTATCTTCTAGCAATGGTTTTTCTCTGTTGATCTACCGTAGTATCC
TATTTTTAAGTTTATTTTATTTTTAAGGAGTATTGTCATCACTTTTCAAGGTGTCTTGACTTCTACACAAAGTATATATATTCAGGACTT
TAAAAAATAGCAGTACACATTTAACAGTAGCGAATTACACCAAAATGATTTACTTTGAGATTTGAATAATTTGCATAGCAGTAAAATGTG
TTTTGTGTAACATACAAATAGAAAAATGACCCAGTATCTTAATTGATACTTACTGGAGAGTATCAGAATTACCCAGCAGCTCTTACAGAA
TGCCATAAATTCTTTAAGACTAAATATTGAAATCAATTATTTGAAGTAATGTTTCTGATTTACTGTTAAAAGTTGCTGAGCTCAGTTTTT
GGAGATATCATTTATGCCTGCCTGTTCCCTTATGACAGTGAGGCCTTCTTTGGCTCCACCTAGTATGATAATCATGGGTTCTGTTTTAGT
TGATGAGAAGTGGCTCCTATGAATGCCTCTGCTCAATTTCTTTTTATTTTACTTTATTTTATTTTTAGGGGTCTCGCCAACTCCTGGGCT
CAAGTGATTCTCCTGCTTCCACCTCCCCACAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCTCTCTGTTCTTTTCAGTGTCTCC
GTGCCATCAGTCAGCAGTGCTTACATGTTTAGCATATTGTCATGCAGTTTCTCTTCTGTTCCCACGAGATATTTTTGGACAAAAAATTGA
CAAAAGTACATGTGTTTTTCCCCACCTATCCCTTAGAAAACCTAATGTGTACTGCTATTTTTAAAACCAAAAAGAGACAGCGTGACGATG
CGTAAAGCATTTTTCTTAGCCTTTCCTTTGTCTTGATCTGTTAATGAGAACAAAACTGCCAGACTCAAAATACTCTACTATTGTGCTGAA
AGAAATACAATTTAGATTGCACAAAATTTGAAAATATAACTCAGCTGTCTTTTAAAAGAGTTGTGTTGTTATCTACAAGACTATTAGCAG
TCTTTTTTCAGAGCAAATTTTAACAGCTAGTTGTGAGTGGTTTAAAATATAGAAAATTATTAAAATCTTAGTTTGAGGGGTTTTATAGTG
GGAGAAAAAACAGGACCAAAGTTTATGTGCCTTCTTCAGTAGTCTTAATTGACCTTTTCTTCCTATTTGAGACTAAAGTAGTATCAGTAT
TCTGGTTTTCAGGAAATATGTACTATATAGTTTTAAAAGAATGTTGTCCCACCAACTATTCATCCAAGCAAAGAATTGTAACTATAAATA
AAGTCTCAGTTACACTTTTGCCTTTATCACATAATATTCATTGTAGAGCATTGTGCAGGTCCAAGAATAGAGCTGCTCAAAATCTTTGTG
GTAGTTTCCTTAGTTTTTGTAACCTGAGGCATATGTTCCAGAGAACAGGGATATTTGTCTGGTCCAGTGACCTTGGTGATCATAGTCATA
ATTGAAAGATGCCTATGGCATGCTTAAATCAGCATTGTCAACTGATTTGTTGTTGTATTATTTTCACTTCTTGGATCTATGTAGTAGTTG
TAATAACAAATATTTAAATAGCTATTTTTTTGATGCCATTAAAAAAATCATACTCTGGCCTTTTTTCCCCCTTACTGTTGTTTCCCAGAT
CTTTTAAAAATTCATCCCATATCCAGAAAGTACCAGTTATAAAGATTGCTGACCAAGCAAAGTTTTGCATCAAAGTGTCACCTCATTGCT
CTGACCAAAGACTGACTGTTGTGGTTTTAACTCCTCTCTGTAAAGCATTTTGCATTTTCCCCAAGCTCCTTTCTGAAAGAAGAACCAGTG
CAGAGCGGCCTTTACTTTCAATTTCTACTGCTGAATAGACTACTTAGAGAAAATGTGAGTTTCAGTGTGAACAGAATGGATTAGGATGAC
GAGTTTGATGGGCATTTTCAGTACTGTATCTAAGAAAAAAAAAATAGCACAGCTAGGAGCCTCTGACATTGTCTGGTGTTTTACGTGGTC
TGTTCATCAAAATTCCCCTTTTCAGTTTTTAAGAATGTTCGTCTAACAGAAGAAAATGCTGTAAATATTTGTAACAACATTTTTTTTAAC
AAGGCCAAAAAAGAAAAAAAGGTTTTTGGGAACAAATGAACTTATAAAGTGGTTTTATATAAAACATCAATTGTCTTGTATATTTTGGAT
AAGCAGCAGTACCAGCTTTCATTTGTAACAGTCTGTGGCATTGGAAAAAAAGGAGTCTGTGATTGTTGAAGTGAATTATGTTATAAATGC
AAAGAGAAGATAAAATATTAAAAAACATATTTTCTAAATGCGTAGTGCATGGTTAATTCAAGCTTCTGTACACTACAGTATATTCCATTT
TCGTTCAGTTTGTATATTTGCTGACTATTACTTGATATCTCTAATCTCTTTTCCTAACAAATATAGCATTGTAGCATGCCTTTTAATAAA

>26862_26862_4_EPB41L4B-PTBP3_EPB41L4B_chr9_112082421_ENST00000374566_PTBP3_chr9_115060196_ENST00000458258_length(amino acids)=640AA_BP=102
MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVF
LLDGTEVSVDLPRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLK
GKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVL
RIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRD
FTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLV
TNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFS
NSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHH

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for EPB41L4B-PTBP3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for EPB41L4B-PTBP3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for EPB41L4B-PTBP3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source