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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AFF3-SAP130 (FusionGDB2 ID:2693)

Fusion Gene Summary for AFF3-SAP130

check button Fusion gene summary
Fusion gene informationFusion gene name: AFF3-SAP130
Fusion gene ID: 2693
HgeneTgene
Gene symbol

AFF3

SAP130

Gene ID

3899

79595

Gene nameAF4/FMR2 family member 3Sin3A associated protein 130
SynonymsLAF4|MLLT2-like-
Cytomap

2q11.2

2q14.3

Type of geneprotein-codingprotein-coding
DescriptionAF4/FMR2 family member 3MLLT2-related proteinlymphoid nuclear protein 4lymphoid nuclear protein related to AF4protein LAF-4histone deacetylase complex subunit SAP130130 kDa Sin3-associated polypeptideSin3-associated polypeptide p130Sin3A associated protein 130kDa
Modification date2020031320200313
UniProtAcc

P51826

.
Ensembl transtripts involved in fusion geneENST00000409236, ENST00000317233, 
ENST00000356421, ENST00000409579, 
ENST00000483600, 		ENST00000259234, 
ENST00000259235, ENST00000357702, 
Fusion gene scores* DoF score17 X 13 X 7=15478 X 6 X 4=192
# samples 178
** MAII scorelog2(17/1547*10)=-3.18586654531133
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/192*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AFF3 [Title/Abstract] AND SAP130 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAFF3(100720862)-SAP130(128770729), # samples:1
Anticipated loss of major functional domain due to fusion event.AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
AFF3-SAP130 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
AFF3-SAP130 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
AFF3-SAP130 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AFF3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SAP130 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ADA775410AFF3chr2

100720862

-SAP130chr2

128770729

-


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Fusion Gene ORF analysis for AFF3-SAP130

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000409236ENST00000259234AFF3chr2

100720862

-SAP130chr2

128770729

-
Frame-shiftENST00000409236ENST00000259235AFF3chr2

100720862

-SAP130chr2

128770729

-
Frame-shiftENST00000409236ENST00000357702AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000317233ENST00000259234AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000317233ENST00000259235AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000317233ENST00000357702AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000356421ENST00000259234AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000356421ENST00000259235AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000356421ENST00000357702AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000409579ENST00000259234AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000409579ENST00000259235AFF3chr2

100720862

-SAP130chr2

128770729

-
In-frameENST00000409579ENST00000357702AFF3chr2

100720862

-SAP130chr2

128770729

-
intron-3CDSENST00000483600ENST00000259234AFF3chr2

100720862

-SAP130chr2

128770729

-
intron-3CDSENST00000483600ENST00000259235AFF3chr2

100720862

-SAP130chr2

128770729

-
intron-3CDSENST00000483600ENST00000357702AFF3chr2

100720862

-SAP130chr2

128770729

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356421AFF3chr2100720862-ENST00000357702SAP130chr2128770729-35411972172751844
ENST00000356421AFF3chr2100720862-ENST00000259235SAP130chr2128770729-34351972172646809
ENST00000356421AFF3chr2100720862-ENST00000259234SAP130chr2128770729-35311972172748843
ENST00000317233AFF3chr2100720862-ENST00000357702SAP130chr2128770729-36332893092843844
ENST00000317233AFF3chr2100720862-ENST00000259235SAP130chr2128770729-35272893092738809
ENST00000317233AFF3chr2100720862-ENST00000259234SAP130chr2128770729-36232893092840843
ENST00000409579AFF3chr2100720862-ENST00000357702SAP130chr2128770729-36302863062840844
ENST00000409579AFF3chr2100720862-ENST00000259235SAP130chr2128770729-35242863062735809
ENST00000409579AFF3chr2100720862-ENST00000259234SAP130chr2128770729-36202863062837843

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356421ENST00000357702AFF3chr2100720862-SAP130chr2128770729-0.0048294790.99517053
ENST00000356421ENST00000259235AFF3chr2100720862-SAP130chr2128770729-0.0054929960.994507
ENST00000356421ENST00000259234AFF3chr2100720862-SAP130chr2128770729-0.0048990320.99510103
ENST00000317233ENST00000357702AFF3chr2100720862-SAP130chr2128770729-0.0053885170.9946115
ENST00000317233ENST00000259235AFF3chr2100720862-SAP130chr2128770729-0.0060795330.99392045
ENST00000317233ENST00000259234AFF3chr2100720862-SAP130chr2128770729-0.0055122730.9944877
ENST00000409579ENST00000357702AFF3chr2100720862-SAP130chr2128770729-0.0047085170.9952915
ENST00000409579ENST00000259235AFF3chr2100720862-SAP130chr2128770729-0.0052712080.99472886
ENST00000409579ENST00000259234AFF3chr2100720862-SAP130chr2128770729-0.004816640.9951834

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Fusion Genomic Features for AFF3-SAP130


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AFF3-SAP130


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:100720862/chr2:128770729)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AFF3

P51826

.
FUNCTION: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double-stranded DNA.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSAP130chr2:100720862chr2:128770729ENST00000259235420234_2382321049.0Compositional biasNote=Poly-Ala
TgeneSAP130chr2:100720862chr2:128770729ENST00000259235420709_8362321049.0Compositional biasNote=Pro-rich
TgeneSAP130chr2:100720862chr2:128770729ENST00000357702421234_2382321084.0Compositional biasNote=Poly-Ala
TgeneSAP130chr2:100720862chr2:128770729ENST00000357702421709_8362321084.0Compositional biasNote=Pro-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAFF3chr2:100720862chr2:128770729ENST00000317233-324413_419171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000317233-324422_432171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000317233-324440_445171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000317233-324670_679171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000356421-224413_419171252.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000356421-224422_432171252.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000356421-224440_445171252.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000356421-224670_679171252.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409236-223413_419171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409236-223422_432171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409236-223440_445171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409236-223670_679171227.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409579-325413_419171252.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409579-325422_432171252.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409579-325440_445171252.0Compositional biasNote=Poly-Ser
HgeneAFF3chr2:100720862chr2:128770729ENST00000409579-325670_679171252.0Compositional biasNote=Poly-Ser
TgeneSAP130chr2:100720862chr2:128770729ENST00000259235420124_1692321049.0Compositional biasNote=Pro-rich
TgeneSAP130chr2:100720862chr2:128770729ENST0000025923542081_852321049.0Compositional biasNote=Poly-Ser
TgeneSAP130chr2:100720862chr2:128770729ENST00000357702421124_1692321084.0Compositional biasNote=Pro-rich
TgeneSAP130chr2:100720862chr2:128770729ENST0000035770242181_852321084.0Compositional biasNote=Poly-Ser


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Fusion Gene Sequence for AFF3-SAP130


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2693_2693_1_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259234_length(transcript)=3623nt_BP=289nt
CGCCAGCGAGAAGAGAGCTCCACGCTCAGCCTCAGAAGAAAGACGTTCAACGACTTACTGGGGAGAGAAAGAAAAGGAACGGGAGCTGAG
AGCTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGG
CGGCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAAT
GGGACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCA
AATGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCT
CCTGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGT
AGGCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACA
CTACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCT
GCAGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGT
ACCATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAG
CAGATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCC
AATCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCA
TACCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCT
GCCATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGA
CATATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTT
GGCACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGA
AAGACTTCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTG
GTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACA
GATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCT
GGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCC
AATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGT
CCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCT
CCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGAT
ATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCT
ACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAG
ACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGAT
GAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCAC
CACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGT
GCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTG
CAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGT
AAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAG
AACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAG
AATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGC
AGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTA
AACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCC
TTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTAT
CTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAG
TGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAA
GTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGAT
CCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAA

>2693_2693_1_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259234_length(amino acids)=843AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ
PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK
PRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDS

--------------------------------------------------------------
>2693_2693_2_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259235_length(transcript)=3527nt_BP=289nt
CGCCAGCGAGAAGAGAGCTCCACGCTCAGCCTCAGAAGAAAGACGTTCAACGACTTACTGGGGAGAGAAAGAAAAGGAACGGGAGCTGAG
AGCTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGG
CGGCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAAT
GGGACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCA
AATGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCT
CCTGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGT
AGGCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACA
CTACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCT
GCAGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGT
ACCATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAG
CAGATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCC
AATCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCA
TACCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCT
GCCATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGA
CATATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTT
GGCACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGA
AAGACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACC
GTGGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCC
ACAGATGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAATCAAAATAAT
GATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCCCCGTCACAA
CCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCATCAGTCACT
GTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATCATGAGGCCA
GTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACAAGTGACCTA
CCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACAAACAGCACT
GATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAGGAAGGTGTG
AGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCACTTTCAGAGG
TACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCTCAAGGCTGG
AAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAGGAAGGGATT
ATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAACTTGTGATG
GATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAACGGGACTGTC
AAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAATGATGGTGGG
GGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGAGGAACCCAT
GACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAACCTGATCTGT
GTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTCCGGTTTATA
GACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTCTCTACACTG
AAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGCCACGGCACC
AAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTGAAATTGTTA
TATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCTTGTTCTGAA
GTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAAAGGACTCAA

>2693_2693_2_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000259235_length(amino acids)=809AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS
MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV
PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVK
AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLT

--------------------------------------------------------------
>2693_2693_3_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000357702_length(transcript)=3633nt_BP=289nt
CGCCAGCGAGAAGAGAGCTCCACGCTCAGCCTCAGAAGAAAGACGTTCAACGACTTACTGGGGAGAGAAAGAAAAGGAACGGGAGCTGAG
AGCTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGG
CGGCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAAT
GGGACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCA
AATGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCT
CCTGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGT
AGGCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACA
CTACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCT
GCAGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGT
ACCATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAG
CAGATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCC
AATCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCA
TACCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCT
GCCATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGA
CATATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTT
GGCACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGA
AAGACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACC
GTGGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCC
ACAGATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACG
TCTGGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTA
TCCAATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCC
AGTCCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCA
CCTCCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATG
GATATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATG
CCTACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATG
GAGACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATT
GATGAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTAC
CACCACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGT
CGTGCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAAC
CTGCAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGG
TGTAAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAAC
AAGAACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATG
AAGAATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAA
AGCAGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTG
TTAAACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCA
GCCTTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGT
TATCTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAG
CAGTGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCC
CAAGTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCA
GATCCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGT

>2693_2693_3_AFF3-SAP130_AFF3_chr2_100720862_ENST00000317233_SAP130_chr2_128770729_ENST00000357702_length(amino acids)=844AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP
QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI
PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRK
KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKE
EKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARD

--------------------------------------------------------------
>2693_2693_4_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259234_length(transcript)=3531nt_BP=197nt
CTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCG
GCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGG
GACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAA
TGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCC
TGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAG
GCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACT
ACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGC
AGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTAC
CATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCA
GATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAA
TCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATA
CCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGC
CATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACA
TATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGG
CACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAA
GACTTCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTGGT
GCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACAGA
TGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCTGG
GTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAA
TCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCC
CCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCC
ATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATAT
CATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTAC
AAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGAC
AAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGA
GGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCA
CTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGC
TCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCA
GGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAA
ACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAA
CGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAA
TGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAG
AGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAA
CCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTT
CCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCT
CTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTG
CCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGT
GAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCC
TTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATA

>2693_2693_4_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259234_length(amino acids)=843AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ
PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK
PRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDS

--------------------------------------------------------------
>2693_2693_5_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259235_length(transcript)=3435nt_BP=197nt
CTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCG
GCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGG
GACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAA
TGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCC
TGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAG
GCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACT
ACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGC
AGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTAC
CATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCA
GATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAA
TCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATA
CCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGC
CATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACA
TATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGG
CACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAA
GACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGT
GGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCAC
AGATGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAATCAAAATAATGA
TCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCCCCGTCACAACC
AGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCATCAGTCACTGT
GGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATCATGAGGCCAGT
TTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACAAGTGACCTACC
ACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACAAACAGCACTGA
TGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAGGAAGGTGTGAG
ATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCACTTTCAGAGGTA
CAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCTCAAGGCTGGAA
AGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAGGAAGGGATTAT
CCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAACTTGTGATGGA
TCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAACGGGACTGTCAA
AAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAATGATGGTGGGGG
TGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGAGGAACCCATGA
CATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAACCTGATCTGTGT
CATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTCCGGTTTATAGA
CTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTCTCTACACTGAA
AATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGCCACGGCACCAA
GCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTGAAATTGTTATA
TCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCTTGTTCTGAAGT
ACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAAAGGACTCAAAG

>2693_2693_5_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000259235_length(amino acids)=809AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS
MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV
PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVK
AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLT

--------------------------------------------------------------
>2693_2693_6_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000357702_length(transcript)=3541nt_BP=197nt
CTGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCG
GCCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGG
GACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAA
TGCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCC
TGCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAG
GCCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACT
ACCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGC
AGCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTAC
CATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCA
GATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAA
TCCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATA
CCCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGC
CATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACA
TATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGG
CACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAA
GACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGT
GGTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCAC
AGATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTC
TGGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATC
CAATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAG
TCCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACC
TCCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGA
TATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCC
TACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGA
GACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGA
TGAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCA
CCACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCG
TGCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCT
GCAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTG
TAAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAA
GAACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAA
GAATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAG
CAGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTT
AAACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGC
CTTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTA
TCTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCA
GTGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCA
AGTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGA
TCCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTA

>2693_2693_6_AFF3-SAP130_AFF3_chr2_100720862_ENST00000356421_SAP130_chr2_128770729_ENST00000357702_length(amino acids)=844AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP
QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI
PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRK
KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKE
EKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARD

--------------------------------------------------------------
>2693_2693_7_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259234_length(transcript)=3620nt_BP=286nt
AAATCCGATCTCAAATAGGAAAGAAGTCTCATTGGCCTTTTGGTCTTCTACCTGTGTCCTGAATTGAGTTTGTTAATCCTCATTCGGAGC
TGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCGG
CCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGGG
ACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAAT
GCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCCT
GCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAGG
CCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACTA
CCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGCA
GCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTACC
ATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCAG
ATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAAT
CCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATAC
CCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGCC
ATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACAT
ATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGGC
ACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAAG
ACTTCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTGGTG
CAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACAGAT
GGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCTGGG
TCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAAT
CAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCC
CCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCA
TCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATC
ATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACA
AGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACA
AACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAG
GAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCAC
TTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCT
CAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAG
GAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAA
CTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAAC
GGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAAT
GATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGA
GGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAAC
CTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTC
CGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTC
TCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGC
CACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTG
AAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCT
TGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAA

>2693_2693_7_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259234_length(amino acids)=843AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPPQ
PPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK
PRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDS

--------------------------------------------------------------
>2693_2693_8_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259235_length(transcript)=3524nt_BP=286nt
AAATCCGATCTCAAATAGGAAAGAAGTCTCATTGGCCTTTTGGTCTTCTACCTGTGTCCTGAATTGAGTTTGTTAATCCTCATTCGGAGC
TGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCGG
CCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGGG
ACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAAT
GCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCCT
GCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAGG
CCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACTA
CCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGCA
GCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTACC
ATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCAG
ATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAAT
CCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATAC
CCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGCC
ATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACAT
ATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGGC
ACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAAG
ACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTG
GTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACA
GATGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCCAATCAAAATAATGAT
CAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGTCCCCCGTCACAACCA
GCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCTCCATCAGTCACTGTG
GGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGATATCATGAGGCCAGTT
TCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCTACAAGTGACCTACCA
CCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAGACAAACAGCACTGAT
GATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGATGAGGAAGGTGTGAGA
TATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCACCACTTTCAGAGGTAC
AGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGTGCTCAAGGCTGGAAA
GTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTGCAGGAAGGGATTATC
CCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGTAAACTTGTGATGGAT
CAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAGAACGGGACTGTCAAA
AAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAGAATGATGGTGGGGGT
GGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGCAGAGGAACCCATGAC
ATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTAAACCTGATCTGTGTC
ATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCCTTCCGGTTTATAGAC
TGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTATCTCTCTACACTGAAA
ATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAGTGCCACGGCACCAAG
CGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAAGTGAAATTGTTATAT
CGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGATCCTTGTTCTGAAGTA
CATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAATAAAGGACTCAAAGA

>2693_2693_8_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000259235_length(amino acids)=809AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS
MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV
PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVK
AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLT

--------------------------------------------------------------
>2693_2693_9_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000357702_length(transcript)=3630nt_BP=286nt
AAATCCGATCTCAAATAGGAAAGAAGTCTCATTGGCCTTTTGGTCTTCTACCTGTGTCCTGAATTGAGTTTGTTAATCCTCATTCGGAGC
TGATCACCTGCCTTTCCAGACCGGAGACGGGCGGCAAGTTTGAAGTCGACACCCAGAGGCCAGTTTGTCCCCCTTCCCGCGCGCGGGCGG
CCCGAGCCTCGGCGGCGGCGGTAGCGGCGGCGGCGACGCTGACACCTCCCACCATGGACAGCTTCGACTTAGCCCTGCTCCAGGAATGGG
ACCTCGAGTCACTGTGGTGCAGCTGCTGCTGCTGTGATGTCCAGTTCTAAAGTAACCACAGTCCTGAGGCCGACCTCACAGCTGCCAAAT
GCTGCTACTGCTCAGCCAGCAGTACAGCACATCATTCACCAACCAATCCAGTCTCGGCCACCTGTGACCACCTCCAATGCCATCCCTCCT
GCTGTGGTAGCAACTGTCTCAGCCACCAGAGCTCAGTCTCCAGTCATCACTACGACAGCGGCGCATGCTACTGATTCAGCACTTAGTAGG
CCAACCTTGTCTATCCAGCATCCTCCATCTGCAGCAATCAGTATTCAGCGTCCTGCCCAGTCACGAGATGTCACAACAAGAATCACACTA
CCATCTCACCCTGCATTAGGGACGCCAAAACAGCAGCTTCATACAATGGCTCAGAAAACAATCTTCAGTACTGGCACGCCAGTGGCTGCA
GCCACAGTAGCACCTATTTTGGCAACCAACACCATTCCTTCAGCGACCACAGCTGGATCTGTGTCACACACGCAAGCTCCCACAAGTACC
ATTGTTACCATGACAGTACCCTCCCATTCCTCCCATGCTACTGCTGTGACCACCTCAAACATCCCAGTCGCCAAGGTGGTGCCCCAGCAG
ATCACGCACACTTCTCCTCGGATCCAGCCAGACTACCCTGCCGAGAGGAGTAGCCTGATTCCCATCTCCGGACATCGGGCCTCTCCCAAT
CCTGTGGCCATGGAAACCCGAAGTGACAACAGACCGTCTGTTCCCGTTCAGTTCCAATATTTTTTGCCAACTTACCCCCCTTCTGCATAC
CCACTGGCGGCACATACCTACACCCCAATCACCAGTTCCGTGTCCACTATCCGACAGTATCCAGTTTCAGCTCAGGCTCCAAACTCTGCC
ATCACAGCTCAGACTGGTGTTGGGGTAGCGTCTACCGTCCACCTAAACCCCATGCAGTTGATGACAGTGGATGCATCGCATGCTCGACAT
ATTCAAGGGATCCAGCCAGCACCCATCAGTACCCAGGGTATCCAGCCGGCCCCCATTGGGACCCCAGGGATACAGCCTGCACCACTTGGC
ACACAGGGAATTCACTCAGCAACCCCAATCAACACACAAGGGCTTCAGCCTGCACCTATGGGTACTCAGCAGCCTCAGCCTGAAGGAAAG
ACTTCAGCAGTGGTGTTGGCAGATGGAGCCACAATTGTGGCCAACCCTATTAGCAATCCATTCAGTGCTGCTCCAGCAGCAACAACCGTG
GTGCAGACCCACAGCCAGAGTGCTAGCACCAACGCTCCCGCCCAGGGCTCATCGCCACGGCCAAGCATACTCCGGAAGAAACCTGCCACA
GATGGAATGGCAGTTCGGAAAACCCTCATTCCTCCTCAGCCTCCTGATGTTGCTAGTCCTCGAGTGGAAAGCTCTATGCGGAGTACGTCT
GGGTCACCTAGGCCTGCAGGTGCCAAACCCAAGTCTGAAATCCACGTGTCTATGGCCACTCCGGTCACTGTGTCCATGGAGACTGTATCC
AATCAAAATAATGATCAGCCTACCATTGCCGTCCCTCCAACTGCCCAGCAGCCCCCACCGACCATTCCAACTATGATTGCAGCAGCCAGT
CCCCCGTCACAACCAGCCGTTGCCCTTTCAACCATTCCTGGAGCGGTCCCCATCACTCCACCCATCACCACCATTGCAGCTGCACCACCT
CCATCAGTCACTGTGGGTGGCAGTCTTTCCTCCGTCTTGGGCCCTCCCGTTCCTGAAATTAAAGTGAAAGAAGAAGTAGAACCAATGGAT
ATCATGAGGCCAGTTTCTGCAGTTCCTCCACTGGCTACCAACACTGTGTCTCCATCTCTTGCATTGCTGGCAAACAACTTGTCCATGCCT
ACAAGTGACCTACCACCTGGTGCCTCCCCAAGGAAAAAGCCTCGAAAGCAACAGCATGTGATCTCAACAGAAGAAGGTGACATGATGGAG
ACAAACAGCACTGATGATGAGAAGTCCACTGCCAAGAGTCTTCTGGTGAAGGCTGAGAAGCGCAAGTCTCCTCCCAAGGAGTATATTGAT
GAGGAAGGTGTGAGATATGTCCCAGTGCGTCCAAGACCCCCCATTACTTTGCTTCGTCACTATCGGAACCCCTGGAAAGCTGCTTACCAC
CACTTTCAGAGGTACAGTGACGTCCGGGTCAAAGAGGAGAAGAAAGCTATGCTGCAGGAAATAGCTAATCAGAAAGGAGTATCCTGTCGT
GCTCAAGGCTGGAAAGTCCACCTCTGTGCTGCCCAGTTACTACAGCTGACGAATCTAGAACATGATGTCTATGAAAGACTTACTAACCTG
CAGGAAGGGATTATCCCAAAGAAAAAAGCAGCAACAGATGATGATCTCCACCGAATAAACGAACTGATACAGGGAAATATGCAGAGGTGT
AAACTTGTGATGGATCAAATCAGTGAAGCCAGAGACTCCATGCTTAAGGTTTTAGATCATAAAGACCGTGTCCTGAAGCTGCTTAACAAG
AACGGGACTGTCAAAAAAGTGTCCAAATTGAAGCGAAAGGAAAAAGTCTAGACCCAGAACAATCAGGAGATTGGAAGCAAATTTATGAAG
AATGATGGTGGGGGTGGGGGGAGGGTTTTGGTTTTTTCCAAAGTGGAACATTGAAATAAAGGAAGTGTTCCTTAGTTCCCGTGTGAAAGC
AGAGGAACCCATGACATCCAAGGGCGTGAAAGGATCAGAGCTGACTGGACATAGTGAGCTGCCTTCTTGCGTTCGGGTGCACCCCTGTTA
AACCTGATCTGTGTCATAAGTGACTCCGGATGCATCAGTGTCCACCAGTTGGAAGCAATGACAAGGATGGCTGGCTGGTGTTTTTCAGCC
TTCCGGTTTATAGACTGTATTTATCTAGTGGATTCCTGCAGGCCCCATACTGAGCCTGGACTGAAAGTATCCACTCGGACCATCTGTTAT
CTCTCTACACTGAAAATAAAACCTCTTCCACCCACCCCATTCGGTTCTTCTGCCTGACCTTCAAATGCCCATGTTGGCCTTTTACAGCAG
TGCCACGGCACCAAGCGAGCTGCCACATCTCACACTCTAAAGGGTTTGAACTATTAGTTCTTGTCATTTTTTAAAAAAAACCATTCCCAA
GTGAAATTGTTATATCGTCTGTCTTGCGTGTGTCAGAACTGGGTTTTTGTGGAGGTTCAGAGCAGGCAACACCATAAGTTGCTCTCAGAT
CCTTGTTCTGAAGTACATTCTTGGTTATCTGTACTTCTGTAGCTGGTGTGATGCTGTTAATTGTATGTACCACACATCTCCAGACGTTAA

>2693_2693_9_AFF3-SAP130_AFF3_chr2_100720862_ENST00000409579_SAP130_chr2_128770729_ENST00000357702_length(amino acids)=844AA_BP=
MSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA
ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH
ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS
SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINT
QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGMAVRKTLIPP
QPPDVASPRVESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI
PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRK
KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKE
EKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARD

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Fusion Gene PPI Analysis for AFF3-SAP130


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AFF3-SAP130


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AFF3-SAP130


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource