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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EPS15L1-ZNF451 (FusionGDB2 ID:27084)

Fusion Gene Summary for EPS15L1-ZNF451

check button Fusion gene summary
Fusion gene informationFusion gene name: EPS15L1-ZNF451
Fusion gene ID: 27084
HgeneTgene
Gene symbol

EPS15L1

ZNF451

Gene ID

58513

26036

Gene nameepidermal growth factor receptor pathway substrate 15 like 1zinc finger protein 451
SynonymsEPS15RCOASTER|dJ417I1.1
Cytomap

19p13.11

6p12.1

Type of geneprotein-codingprotein-coding
Descriptionepidermal growth factor receptor substrate 15-like 1epidermal growth factor receptor substrate EPS15Reps15-related proteinE3 SUMO-protein ligase ZNF451E3 SUMO-protein transferase ZNF451coactivator for steroid receptors
Modification date2020031320200320
UniProtAcc

Q9UBC2

.
Ensembl transtripts involved in fusion geneENST00000248070, ENST00000455140, 
ENST00000535753, ENST00000594975, 
ENST00000597937, ENST00000602009, 
ENST00000370702, ENST00000370708, 
ENST00000370710, ENST00000510989, 
ENST00000357489, ENST00000370706, 
ENST00000491832, 
Fusion gene scores* DoF score23 X 17 X 14=54747 X 6 X 7=294
# samples 348
** MAII scorelog2(34/5474*10)=-4.00898878322726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/294*10)=-1.877744249949
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EPS15L1 [Title/Abstract] AND ZNF451 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEPS15L1(16495940)-ZNF451(57018659), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneZNF451

GO:0016925

protein sumoylation

26524494


check buttonFusion gene breakpoints across EPS15L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZNF451 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-TM-A7CF-01AEPS15L1chr19

16495940

-ZNF451chr6

57018659

+


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Fusion Gene ORF analysis for EPS15L1-ZNF451

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000248070ENST00000370702EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000248070ENST00000370708EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000248070ENST00000370710EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000248070ENST00000510989EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000455140ENST00000370702EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000455140ENST00000370708EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000455140ENST00000370710EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000455140ENST00000510989EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000535753ENST00000370702EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000535753ENST00000370708EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000535753ENST00000370710EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000535753ENST00000510989EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000594975ENST00000370702EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000594975ENST00000370708EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000594975ENST00000370710EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
5CDS-intronENST00000594975ENST00000510989EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000248070ENST00000357489EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000248070ENST00000370706EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000248070ENST00000491832EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000455140ENST00000357489EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000455140ENST00000370706EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000455140ENST00000491832EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000535753ENST00000357489EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000535753ENST00000370706EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000535753ENST00000491832EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000594975ENST00000357489EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000594975ENST00000370706EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
In-frameENST00000594975ENST00000491832EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-3CDSENST00000597937ENST00000357489EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-3CDSENST00000597937ENST00000370706EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-3CDSENST00000597937ENST00000491832EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-3CDSENST00000602009ENST00000357489EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-3CDSENST00000602009ENST00000370706EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-3CDSENST00000602009ENST00000491832EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000597937ENST00000370702EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000597937ENST00000370708EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000597937ENST00000370710EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000597937ENST00000510989EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000602009ENST00000370702EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000602009ENST00000370708EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000602009ENST00000370710EPS15L1chr19

16495940

-ZNF451chr6

57018659

+
intron-intronENST00000602009ENST00000510989EPS15L1chr19

16495940

-ZNF451chr6

57018659

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000455140EPS15L1chr1916495940-ENST00000370706ZNF451chr657018659+44552314672616849
ENST00000455140EPS15L1chr1916495940-ENST00000357489ZNF451chr657018659+43492314672616849
ENST00000455140EPS15L1chr1916495940-ENST00000491832ZNF451chr657018659+29982314672556829
ENST00000248070EPS15L1chr1916495940-ENST00000370706ZNF451chr657018659+4528238722689895
ENST00000248070EPS15L1chr1916495940-ENST00000357489ZNF451chr657018659+4422238722689895
ENST00000248070EPS15L1chr1916495940-ENST00000491832ZNF451chr657018659+3071238722629875
ENST00000535753EPS15L1chr1916495940-ENST00000370706ZNF451chr657018659+44192278312580849
ENST00000535753EPS15L1chr1916495940-ENST00000357489ZNF451chr657018659+43132278312580849
ENST00000535753EPS15L1chr1916495940-ENST00000491832ZNF451chr657018659+29622278312520829
ENST00000594975EPS15L1chr1916495940-ENST00000370706ZNF451chr657018659+4534239322695897
ENST00000594975EPS15L1chr1916495940-ENST00000357489ZNF451chr657018659+4428239322695897
ENST00000594975EPS15L1chr1916495940-ENST00000491832ZNF451chr657018659+3077239322635877

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000455140ENST00000370706EPS15L1chr1916495940-ZNF451chr657018659+0.0004336270.9995664
ENST00000455140ENST00000357489EPS15L1chr1916495940-ZNF451chr657018659+0.0004584430.99954164
ENST00000455140ENST00000491832EPS15L1chr1916495940-ZNF451chr657018659+0.0055197390.99448025
ENST00000248070ENST00000370706EPS15L1chr1916495940-ZNF451chr657018659+0.000576880.99942315
ENST00000248070ENST00000357489EPS15L1chr1916495940-ZNF451chr657018659+0.0006111390.9993888
ENST00000248070ENST00000491832EPS15L1chr1916495940-ZNF451chr657018659+0.0065104810.9934895
ENST00000535753ENST00000370706EPS15L1chr1916495940-ZNF451chr657018659+0.0004242110.9995758
ENST00000535753ENST00000357489EPS15L1chr1916495940-ZNF451chr657018659+0.0004477290.9995522
ENST00000535753ENST00000491832EPS15L1chr1916495940-ZNF451chr657018659+0.005332570.9946674
ENST00000594975ENST00000370706EPS15L1chr1916495940-ZNF451chr657018659+0.0005275260.99947244
ENST00000594975ENST00000357489EPS15L1chr1916495940-ZNF451chr657018659+0.0005587290.9994412
ENST00000594975ENST00000491832EPS15L1chr1916495940-ZNF451chr657018659+0.0062331280.9937669

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Fusion Genomic Features for EPS15L1-ZNF451


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EPS15L1chr1916495939-ZNF451chr657018658+0.0090899970.99091
EPS15L1chr1916495939-ZNF451chr657018658+0.0090899970.99091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EPS15L1-ZNF451


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:16495940/chr6:57018659)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EPS15L1

Q9UBC2

.
FUNCTION: Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. {ECO:0000269|PubMed:22648170, ECO:0000269|PubMed:9407958}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123172_184749865.0Calcium bindingOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124172_184749911.0Calcium bindingOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122172_184749755.0Calcium bindingOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123386_553749865.0Coiled coilOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124386_553749911.0Coiled coilOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122386_553749755.0Coiled coilOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123127_215749865.0DomainEH 2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123159_194749865.0DomainEF-hand
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-212315_104749865.0DomainEH 1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123275_365749865.0DomainEH 3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124127_215749911.0DomainEH 2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124159_194749911.0DomainEF-hand
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-212415_104749911.0DomainEH 1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124275_365749911.0DomainEH 3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122127_215749755.0DomainEH 2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122159_194749755.0DomainEF-hand
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-212215_104749755.0DomainEH 1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122275_365749755.0DomainEH 3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123618_620749865.0RepeatNote=1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123640_642749865.0RepeatNote=2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123645_647749865.0RepeatNote=3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123650_652749865.0RepeatNote=4
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123656_658749865.0RepeatNote=5
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123661_663749865.0RepeatNote=6
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123667_669749865.0RepeatNote=7
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123685_687749865.0RepeatNote=8
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123690_692749865.0RepeatNote=9
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123709_711749865.0RepeatNote=10
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123728_730749865.0RepeatNote=11
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124618_620749911.0RepeatNote=1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124640_642749911.0RepeatNote=2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124645_647749911.0RepeatNote=3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124650_652749911.0RepeatNote=4
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124656_658749911.0RepeatNote=5
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124661_663749911.0RepeatNote=6
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124667_669749911.0RepeatNote=7
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124685_687749911.0RepeatNote=8
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124690_692749911.0RepeatNote=9
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124709_711749911.0RepeatNote=10
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124728_730749911.0RepeatNote=11
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122618_620749755.0RepeatNote=1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122640_642749755.0RepeatNote=2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122645_647749755.0RepeatNote=3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122650_652749755.0RepeatNote=4
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122656_658749755.0RepeatNote=5
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122661_663749755.0RepeatNote=6
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122667_669749755.0RepeatNote=7
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122685_687749755.0RepeatNote=8
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122690_692749755.0RepeatNote=9
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122709_711749755.0RepeatNote=10
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122728_730749755.0RepeatNote=11
TgeneZNF451chr19:16495940chr6:57018659ENST0000035748910141050_10619131014.0RegionImportant for ubiquitin binding
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070611151050_10619611062.0RegionImportant for ubiquitin binding
TgeneZNF451chr19:16495940chr6:57018659ENST00000370708041050_10610560.0RegionImportant for ubiquitin binding
TgeneZNF451chr19:16495940chr6:57018659ENST00000370708041_2460560.0RegionSufficient for E3 SUMO-protein ligase activity
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804169_1950560.0Zinc fingerC2H2-type 1
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804253_2770560.0Zinc fingerC2H2-type 2
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804315_3370560.0Zinc fingerC2H2-type 3
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804362_3860560.0Zinc fingerC2H2-type 4
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804498_5210560.0Zinc fingerC2H2-type 5
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804531_5540560.0Zinc fingerC2H2-type 6
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804606_6310560.0Zinc fingerC2H2-type 7%3B atypical
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804636_6590560.0Zinc fingerC2H2-type 8
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804667_6900560.0Zinc fingerC2H2-type 9
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804753_7760560.0Zinc fingerC2H2-type 10
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070804789_8120560.0Zinc fingerC2H2-type 11

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116172_1840602.0Calcium bindingOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116386_5530602.0Coiled coilOntology_term=ECO:0000255
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123750_816749865.0Compositional biasNote=Pro-rich
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124750_816749911.0Compositional biasNote=Pro-rich
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122750_816749755.0Compositional biasNote=Pro-rich
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116750_8160602.0Compositional biasNote=Pro-rich
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116127_2150602.0DomainEH 2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116159_1940602.0DomainEF-hand
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-11615_1040602.0DomainEH 1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116275_3650602.0DomainEH 3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123618_835749865.0RegionNote=15 X 3 AA repeats of D-P-F
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124618_835749911.0RegionNote=15 X 3 AA repeats of D-P-F
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122618_835749755.0RegionNote=15 X 3 AA repeats of D-P-F
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116618_8350602.0RegionNote=15 X 3 AA repeats of D-P-F
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123754_756749865.0RepeatNote=12
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123806_808749865.0RepeatNote=13
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123812_814749865.0RepeatNote=14
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-2123833_835749865.0RepeatNote=15
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124754_756749911.0RepeatNote=12
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124806_808749911.0RepeatNote=13
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124812_814749911.0RepeatNote=14
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-2124833_835749911.0RepeatNote=15
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122754_756749755.0RepeatNote=12
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122806_808749755.0RepeatNote=13
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122812_814749755.0RepeatNote=14
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-2122833_835749755.0RepeatNote=15
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116618_6200602.0RepeatNote=1
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116640_6420602.0RepeatNote=2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116645_6470602.0RepeatNote=3
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116650_6520602.0RepeatNote=4
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116656_6580602.0RepeatNote=5
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116661_6630602.0RepeatNote=6
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116667_6690602.0RepeatNote=7
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116685_6870602.0RepeatNote=8
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116690_6920602.0RepeatNote=9
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116709_7110602.0RepeatNote=10
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116728_7300602.0RepeatNote=11
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116754_7560602.0RepeatNote=12
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116806_8080602.0RepeatNote=13
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116812_8140602.0RepeatNote=14
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-116833_8350602.0RepeatNote=15
TgeneZNF451chr19:16495940chr6:57018659ENST0000035748910141_2469131014.0RegionSufficient for E3 SUMO-protein ligase activity
TgeneZNF451chr19:16495940chr6:57018659ENST0000037070611151_2469611062.0RegionSufficient for E3 SUMO-protein ligase activity
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014169_1959131014.0Zinc fingerC2H2-type 1
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014253_2779131014.0Zinc fingerC2H2-type 2
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014315_3379131014.0Zinc fingerC2H2-type 3
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014362_3869131014.0Zinc fingerC2H2-type 4
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014498_5219131014.0Zinc fingerC2H2-type 5
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014531_5549131014.0Zinc fingerC2H2-type 6
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014606_6319131014.0Zinc fingerC2H2-type 7%3B atypical
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014636_6599131014.0Zinc fingerC2H2-type 8
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014667_6909131014.0Zinc fingerC2H2-type 9
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014753_7769131014.0Zinc fingerC2H2-type 10
TgeneZNF451chr19:16495940chr6:57018659ENST000003574891014789_8129131014.0Zinc fingerC2H2-type 11
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115169_1959611062.0Zinc fingerC2H2-type 1
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115253_2779611062.0Zinc fingerC2H2-type 2
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115315_3379611062.0Zinc fingerC2H2-type 3
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115362_3869611062.0Zinc fingerC2H2-type 4
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115498_5219611062.0Zinc fingerC2H2-type 5
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115531_5549611062.0Zinc fingerC2H2-type 6
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115606_6319611062.0Zinc fingerC2H2-type 7%3B atypical
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115636_6599611062.0Zinc fingerC2H2-type 8
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115667_6909611062.0Zinc fingerC2H2-type 9
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115753_7769611062.0Zinc fingerC2H2-type 10
TgeneZNF451chr19:16495940chr6:57018659ENST000003707061115789_8129611062.0Zinc fingerC2H2-type 11


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Fusion Gene Sequence for EPS15L1-ZNF451


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27084_27084_1_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000248070_ZNF451_chr6_57018659_ENST00000357489_length(transcript)=4422nt_BP=2387nt
ACATGCGTGGCCCTGTCTACGGCCCCGCCCTCTCCCGGGACAGGCGGCCTGCGCACCGCCCTCCCGTCGTCCCAGTGCGCACGCGTGGCT
GCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCA
CTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAA
AGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCT
ATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTC
ACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGA
TTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCC
TGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAG
CCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCC
CCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCC
TGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCC
TGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAG
CACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGG
TCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCT
CTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGG
AACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCA
GTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGA
GCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCC
AGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAG
TCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCC
GCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCG
AAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAG
AGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGA
ATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCA
CTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACC
CCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGT
CCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTCCTTTCA
CCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACT
TAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAACATGGGTGCCAAAAATA
CTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGAAATGTAATTAAAGATAT
TACCACACAACATCAAGTGGCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCAGAAATCCACTATTACAA
ATGTATTTGAAAACATGTTTTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGTGCAAACATGTACAGAAG
AAATAGAATACATGTTCATGCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTTGAATTTATATATTTAGA
TTTAAAGGATTAAAAAAAAGGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTGTACTGTACAAATGATGC
TAGTTTATTTTTTTAGCAGTGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTTCTCATGTGGCACTATTA
TATAATACCTTTGAGATCTTTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAAATTTTATCAGCAATGTT
CTTTGTGGGTGCCATGCATATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACCTTAATTTTTAAGAAATA
ATTTAAATGAAACAATTTCCATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAAGGGAATGGTGTCAGAAT
ATTTGCATAAAATTATTTTTCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATAATGTTGAAAGCCTACTC
AGGAATAATCTTCCTTAACTCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATTGTCAGTTTCCTTCATTT
GGTATTACATATTTAATTCTTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGACTAAGAAGGGCTTGTCAT
ATTATCTTTGTGTATATGCTTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTATTTACCAAACTTAAAAA
CATTTCTATAAATATAAAGCTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTGTAACACTAAATATTTTA
GTGTGAAATTGAATTTTTTTATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTCACTTCTGTTCCTCCCTG
CTTGCATTTTTTAAAAACTAGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTGCTTTTAGTTTGTATGTT
TAAGTGGTCAAGCAAGGCTCTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAATGGGAGCAAAAGAGGCA
TTCCAGAAAGAAGAGTAGTTAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTCTACACAAAGGTGTGATG
GACACTGATGCTCTATTAAGAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGGAAAGGGATATTTCATCA
TGACTGTTAAGAAAAGGTAACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATTTCTACTTGTTAAATAATTAAAAATC

>27084_27084_1_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000248070_ZNF451_chr6_57018659_ENST00000357489_length(amino acids)=895AA_BP=795
MRGPVYGPALSRDRRPAHRPPVVPVRTRGCSPAPVPPALGARVRGKMAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLK
KSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGI
FESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVP
VLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLA
HIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLE
QDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQ
EDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSE
GVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSAT
DDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFT

--------------------------------------------------------------
>27084_27084_2_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000248070_ZNF451_chr6_57018659_ENST00000370706_length(transcript)=4528nt_BP=2387nt
ACATGCGTGGCCCTGTCTACGGCCCCGCCCTCTCCCGGGACAGGCGGCCTGCGCACCGCCCTCCCGTCGTCCCAGTGCGCACGCGTGGCT
GCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCA
CTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAA
AGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCT
ATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTC
ACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGA
TTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCC
TGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAG
CCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCC
CCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCC
TGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCC
TGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAG
CACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGG
TCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCT
CTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGG
AACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCA
GTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGA
GCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCC
AGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAG
TCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCC
GCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCG
AAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAG
AGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGA
ATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCA
CTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACC
CCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGT
CCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTCCTTTCA
CCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACT
TAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAACATGGGTGCCAAAAATA
CTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGAAATGTAATTAAAGATAT
TACCACACAACATCAAGTGGCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCAGAAATCCACTATTACAA
ATGTATTTGAAAACATGTTTTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGTGCAAACATGTACAGAAG
AAATAGAATACATGTTCATGCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTTGAATTTATATATTTAGA
TTTAAAGGATTAAAAAAAAGGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTGTACTGTACAAATGATGC
TAGTTTATTTTTTTAGCAGTGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTTCTCATGTGGCACTATTA
TATAATACCTTTGAGATCTTTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAAATTTTATCAGCAATGTT
CTTTGTGGGTGCCATGCATATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACCTTAATTTTTAAGAAATA
ATTTAAATGAAACAATTTCCATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAAGGGAATGGTGTCAGAAT
ATTTGCATAAAATTATTTTTCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATAATGTTGAAAGCCTACTC
AGGAATAATCTTCCTTAACTCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATTGTCAGTTTCCTTCATTT
GGTATTACATATTTAATTCTTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGACTAAGAAGGGCTTGTCAT
ATTATCTTTGTGTATATGCTTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTATTTACCAAACTTAAAAA
CATTTCTATAAATATAAAGCTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTGTAACACTAAATATTTTA
GTGTGAAATTGAATTTTTTTATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTCACTTCTGTTCCTCCCTG
CTTGCATTTTTTAAAAACTAGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTGCTTTTAGTTTGTATGTT
TAAGTGGTCAAGCAAGGCTCTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAATGGGAGCAAAAGAGGCA
TTCCAGAAAGAAGAGTAGTTAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTCTACACAAAGGTGTGATG
GACACTGATGCTCTATTAAGAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGGAAAGGGATATTTCATCA
TGACTGTTAAGAAAAGGTAACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATTTCTACTTGTTAAATAATTAAAAATC
ATCTTAAAATTCATACTTTGACTTTAATTTAGACACAAGGAGATGTAATCGCTGTGTAACATCAGAGAAAGCTATATGGATTATCGTCAG

>27084_27084_2_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000248070_ZNF451_chr6_57018659_ENST00000370706_length(amino acids)=895AA_BP=795
MRGPVYGPALSRDRRPAHRPPVVPVRTRGCSPAPVPPALGARVRGKMAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLK
KSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGI
FESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVP
VLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLA
HIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLE
QDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQ
EDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSE
GVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSAT
DDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFT

--------------------------------------------------------------
>27084_27084_3_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000248070_ZNF451_chr6_57018659_ENST00000491832_length(transcript)=3071nt_BP=2387nt
ACATGCGTGGCCCTGTCTACGGCCCCGCCCTCTCCCGGGACAGGCGGCCTGCGCACCGCCCTCCCGTCGTCCCAGTGCGCACGCGTGGCT
GCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCA
CTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAA
AGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCT
ATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTC
ACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGA
TTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCC
TGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAG
CCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCC
CCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCC
TGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCC
TGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAG
CACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGG
TCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCT
CTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGG
AACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCA
GTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGA
GCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCC
AGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAG
TCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCC
GCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCG
AAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAG
AGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGA
ATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCA
CTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACC
CCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGT
CCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTCCTTTCA
CCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACT
TAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGGTACGCAGCTGCAGTCACAGTGCAAACCACCCAAGA
GGAGGAGACTTCACTGCTGAGAGAAACCAATAAACTGCTGTCCGCTAGTGAACTGTTGCCTGCTTGCTAAACCATCATGTTCTCTTACTT
CTATCTTACTTATCTTTTTTAAAAAAATCTCACTTTCATTCTTTAGTGTTTTAGAAGGAGGATGAATTCATAATAATTTTCTGGAGCTTT
TTTTGATCTAGTAGATAAAATCTATATTGATGTATATAAAACATATATTCATGTGTTACAGTATGTTACTACAATTTTAAAAGCTCAGAA
TTCAGATCTTCACTTTGTTTCTGAAATTCCAAGTTGACCTTCAGTTTTTTAGAAAGCAGTGCGCTTAGAGGTGAAAACCAGAAAGCAATA
ACAAAGGTGATCATTTAAGAGGTTGACAGTGACAAAATAAAACGCTGATAGGCTTTTAGGTCCTTAGAGAAGTGGGTACATCCTATCTTA

>27084_27084_3_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000248070_ZNF451_chr6_57018659_ENST00000491832_length(amino acids)=875AA_BP=795
MRGPVYGPALSRDRRPAHRPPVVPVRTRGCSPAPVPPALGARVRGKMAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLK
KSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGI
FESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVP
VLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLA
HIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLE
QDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQ
EDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSE
GVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSAT
DDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFT

--------------------------------------------------------------
>27084_27084_4_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000455140_ZNF451_chr6_57018659_ENST00000357489_length(transcript)=4349nt_BP=2314nt
AGTGCGCACGCGTGGCTGCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCT
CTCCCAGCAGATTCCCACTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGA
AGCTGCGCTTTTTCTAAAGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTT
GGACAAACAGGGTTTCTATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCAT
GCCACCGCCTAAATTTCACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAA
GGCCAAATTTGATGGGATTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAA
GCTGCCTCTTGATGTCCTGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCAT
GCACTTGGTGTACCGAGCCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGT
GTTCCCTGGCGCCGTCCCCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCT
CAACAGCACAGGGAGCCTGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCG
ATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCT
CACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTA
TTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGG
CCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAG
AGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCT
AGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAA
GCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGA
ATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAG
CATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTC
CCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGA
CCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATT
TAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAA
AGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCC
ATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTT
ACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGA
TCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACC
CAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATAT
ACTAAACCCTCACCACTTAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAA
CATGGGTGCCAAAAATACTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGA
AATGTAATTAAAGATATTACCACACAACATCAAGTGGCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCA
GAAATCCACTATTACAAATGTATTTGAAAACATGTTTTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGT
GCAAACATGTACAGAAGAAATAGAATACATGTTCATGCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTT
GAATTTATATATTTAGATTTAAAGGATTAAAAAAAAGGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTG
TACTGTACAAATGATGCTAGTTTATTTTTTTAGCAGTGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTT
CTCATGTGGCACTATTATATAATACCTTTGAGATCTTTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAA
ATTTTATCAGCAATGTTCTTTGTGGGTGCCATGCATATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACC
TTAATTTTTAAGAAATAATTTAAATGAAACAATTTCCATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAA
GGGAATGGTGTCAGAATATTTGCATAAAATTATTTTTCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATA
ATGTTGAAAGCCTACTCAGGAATAATCTTCCTTAACTCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATT
GTCAGTTTCCTTCATTTGGTATTACATATTTAATTCTTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGAC
TAAGAAGGGCTTGTCATATTATCTTTGTGTATATGCTTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTA
TTTACCAAACTTAAAAACATTTCTATAAATATAAAGCTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTG
TAACACTAAATATTTTAGTGTGAAATTGAATTTTTTTATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTC
ACTTCTGTTCCTCCCTGCTTGCATTTTTTAAAAACTAGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTG
CTTTTAGTTTGTATGTTTAAGTGGTCAAGCAAGGCTCTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAA
TGGGAGCAAAAGAGGCATTCCAGAAAGAAGAGTAGTTAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTC
TACACAAAGGTGTGATGGACACTGATGCTCTATTAAGAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGG
AAAGGGATATTTCATCATGACTGTTAAGAAAAGGTAACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATTTCTACTTG

>27084_27084_4_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000455140_ZNF451_chr6_57018659_ENST00000357489_length(amino acids)=849AA_BP=749
MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT
LSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD
RDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWV
VPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP
PSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLD
EMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI
NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDP
FKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKG
SDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTT

--------------------------------------------------------------
>27084_27084_5_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000455140_ZNF451_chr6_57018659_ENST00000370706_length(transcript)=4455nt_BP=2314nt
AGTGCGCACGCGTGGCTGCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCT
CTCCCAGCAGATTCCCACTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGA
AGCTGCGCTTTTTCTAAAGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTT
GGACAAACAGGGTTTCTATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCAT
GCCACCGCCTAAATTTCACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAA
GGCCAAATTTGATGGGATTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAA
GCTGCCTCTTGATGTCCTGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCAT
GCACTTGGTGTACCGAGCCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGT
GTTCCCTGGCGCCGTCCCCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCT
CAACAGCACAGGGAGCCTGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCG
ATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCT
CACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTA
TTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGG
CCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAG
AGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCT
AGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAA
GCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGA
ATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAG
CATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTC
CCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGA
CCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATT
TAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAA
AGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCC
ATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTT
ACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGA
TCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACC
CAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATAT
ACTAAACCCTCACCACTTAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAA
CATGGGTGCCAAAAATACTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGA
AATGTAATTAAAGATATTACCACACAACATCAAGTGGCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCA
GAAATCCACTATTACAAATGTATTTGAAAACATGTTTTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGT
GCAAACATGTACAGAAGAAATAGAATACATGTTCATGCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTT
GAATTTATATATTTAGATTTAAAGGATTAAAAAAAAGGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTG
TACTGTACAAATGATGCTAGTTTATTTTTTTAGCAGTGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTT
CTCATGTGGCACTATTATATAATACCTTTGAGATCTTTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAA
ATTTTATCAGCAATGTTCTTTGTGGGTGCCATGCATATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACC
TTAATTTTTAAGAAATAATTTAAATGAAACAATTTCCATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAA
GGGAATGGTGTCAGAATATTTGCATAAAATTATTTTTCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATA
ATGTTGAAAGCCTACTCAGGAATAATCTTCCTTAACTCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATT
GTCAGTTTCCTTCATTTGGTATTACATATTTAATTCTTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGAC
TAAGAAGGGCTTGTCATATTATCTTTGTGTATATGCTTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTA
TTTACCAAACTTAAAAACATTTCTATAAATATAAAGCTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTG
TAACACTAAATATTTTAGTGTGAAATTGAATTTTTTTATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTC
ACTTCTGTTCCTCCCTGCTTGCATTTTTTAAAAACTAGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTG
CTTTTAGTTTGTATGTTTAAGTGGTCAAGCAAGGCTCTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAA
TGGGAGCAAAAGAGGCATTCCAGAAAGAAGAGTAGTTAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTC
TACACAAAGGTGTGATGGACACTGATGCTCTATTAAGAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGG
AAAGGGATATTTCATCATGACTGTTAAGAAAAGGTAACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATTTCTACTTG
TTAAATAATTAAAAATCATCTTAAAATTCATACTTTGACTTTAATTTAGACACAAGGAGATGTAATCGCTGTGTAACATCAGAGAAAGCT

>27084_27084_5_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000455140_ZNF451_chr6_57018659_ENST00000370706_length(amino acids)=849AA_BP=749
MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT
LSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD
RDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWV
VPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP
PSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLD
EMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI
NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDP
FKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKG
SDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTT

--------------------------------------------------------------
>27084_27084_6_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000455140_ZNF451_chr6_57018659_ENST00000491832_length(transcript)=2998nt_BP=2314nt
AGTGCGCACGCGTGGCTGCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCT
CTCCCAGCAGATTCCCACTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGA
AGCTGCGCTTTTTCTAAAGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTT
GGACAAACAGGGTTTCTATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCAT
GCCACCGCCTAAATTTCACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAA
GGCCAAATTTGATGGGATTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAA
GCTGCCTCTTGATGTCCTGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCAT
GCACTTGGTGTACCGAGCCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGT
GTTCCCTGGCGCCGTCCCCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCT
CAACAGCACAGGGAGCCTGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCG
ATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCT
CACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTA
TTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGG
CCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAG
AGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCT
AGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAA
GCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGA
ATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAG
CATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTC
CCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGA
CCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATT
TAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAA
AGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCC
ATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTT
ACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGA
TCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACC
CAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATAT
ACTAAACCCTCACCACTTAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGGTACGCAGCTGCAGTCACA
GTGCAAACCACCCAAGAGGAGGAGACTTCACTGCTGAGAGAAACCAATAAACTGCTGTCCGCTAGTGAACTGTTGCCTGCTTGCTAAACC
ATCATGTTCTCTTACTTCTATCTTACTTATCTTTTTTAAAAAAATCTCACTTTCATTCTTTAGTGTTTTAGAAGGAGGATGAATTCATAA
TAATTTTCTGGAGCTTTTTTTGATCTAGTAGATAAAATCTATATTGATGTATATAAAACATATATTCATGTGTTACAGTATGTTACTACA
ATTTTAAAAGCTCAGAATTCAGATCTTCACTTTGTTTCTGAAATTCCAAGTTGACCTTCAGTTTTTTAGAAAGCAGTGCGCTTAGAGGTG
AAAACCAGAAAGCAATAACAAAGGTGATCATTTAAGAGGTTGACAGTGACAAAATAAAACGCTGATAGGCTTTTAGGTCCTTAGAGAAGT

>27084_27084_6_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000455140_ZNF451_chr6_57018659_ENST00000491832_length(amino acids)=829AA_BP=749
MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT
LSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD
RDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWV
VPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP
PSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLD
EMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI
NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDP
FKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKG
SDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTT

--------------------------------------------------------------
>27084_27084_7_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000535753_ZNF451_chr6_57018659_ENST00000357489_length(transcript)=4313nt_BP=2278nt
CCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCACTGGAAATTCGTTGTATGA
ATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAAAGAAGTCTGGCCTCTCGGA
CATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCTATGTTGCACTGAGACTGGT
GGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTCACGACACCAGCAGCCCTCT
GATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGATTTTTGAAAGCCTCTTGCC
CATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCCTGGGCAGGGTCTGGGACCT
CAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAGCCCTGGAGAAGGAGCCCGT
GCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCCCCGTCCTGCCTGCCAGCCC
CCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCCTGTCCCCCAAGCACAGCCT
CAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG
CTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCA
AGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACTTAGAGGGAGATATGATGTG
TGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAACATGGGTGCCAAAAATACTTCAATAGGAGAAGAATT
TATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGAAATGTAATTAAAGATATTACCACACAACATCAAGTG
GCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCAGAAATCCACTATTACAAATGTATTTGAAAACATGTT
TTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGTGCAAACATGTACAGAAGAAATAGAATACATGTTCAT
GCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTTGAATTTATATATTTAGATTTAAAGGATTAAAAAAAA
GGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTGTACTGTACAAATGATGCTAGTTTATTTTTTTAGCAG
TGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTTCTCATGTGGCACTATTATATAATACCTTTGAGATCT
TTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAAATTTTATCAGCAATGTTCTTTGTGGGTGCCATGCAT
ATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACCTTAATTTTTAAGAAATAATTTAAATGAAACAATTTC
CATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAAGGGAATGGTGTCAGAATATTTGCATAAAATTATTTT
TCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATAATGTTGAAAGCCTACTCAGGAATAATCTTCCTTAAC
TCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATTGTCAGTTTCCTTCATTTGGTATTACATATTTAATTC
TTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGACTAAGAAGGGCTTGTCATATTATCTTTGTGTATATGC
TTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTATTTACCAAACTTAAAAACATTTCTATAAATATAAAG
CTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTGTAACACTAAATATTTTAGTGTGAAATTGAATTTTTT
TATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTCACTTCTGTTCCTCCCTGCTTGCATTTTTTAAAAACT
AGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTGCTTTTAGTTTGTATGTTTAAGTGGTCAAGCAAGGCT
CTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAATGGGAGCAAAAGAGGCATTCCAGAAAGAAGAGTAGT
TAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTCTACACAAAGGTGTGATGGACACTGATGCTCTATTAA
GAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGGAAAGGGATATTTCATCATGACTGTTAAGAAAAGGTA

>27084_27084_7_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000535753_ZNF451_chr6_57018659_ENST00000357489_length(amino acids)=849AA_BP=749
MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT
LSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD
RDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWV
VPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP
PSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLD
EMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI
NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDP
FKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKG
SDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTT

--------------------------------------------------------------
>27084_27084_8_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000535753_ZNF451_chr6_57018659_ENST00000370706_length(transcript)=4419nt_BP=2278nt
CCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCACTGGAAATTCGTTGTATGA
ATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAAAGAAGTCTGGCCTCTCGGA
CATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCTATGTTGCACTGAGACTGGT
GGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTCACGACACCAGCAGCCCTCT
GATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGATTTTTGAAAGCCTCTTGCC
CATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCCTGGGCAGGGTCTGGGACCT
CAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAGCCCTGGAGAAGGAGCCCGT
GCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCCCCGTCCTGCCTGCCAGCCC
CCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCCTGTCCCCCAAGCACAGCCT
CAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG
CTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCA
AGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACTTAGAGGGAGATATGATGTG
TGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAACATGGGTGCCAAAAATACTTCAATAGGAGAAGAATT
TATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGAAATGTAATTAAAGATATTACCACACAACATCAAGTG
GCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCAGAAATCCACTATTACAAATGTATTTGAAAACATGTT
TTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGTGCAAACATGTACAGAAGAAATAGAATACATGTTCAT
GCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTTGAATTTATATATTTAGATTTAAAGGATTAAAAAAAA
GGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTGTACTGTACAAATGATGCTAGTTTATTTTTTTAGCAG
TGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTTCTCATGTGGCACTATTATATAATACCTTTGAGATCT
TTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAAATTTTATCAGCAATGTTCTTTGTGGGTGCCATGCAT
ATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACCTTAATTTTTAAGAAATAATTTAAATGAAACAATTTC
CATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAAGGGAATGGTGTCAGAATATTTGCATAAAATTATTTT
TCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATAATGTTGAAAGCCTACTCAGGAATAATCTTCCTTAAC
TCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATTGTCAGTTTCCTTCATTTGGTATTACATATTTAATTC
TTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGACTAAGAAGGGCTTGTCATATTATCTTTGTGTATATGC
TTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTATTTACCAAACTTAAAAACATTTCTATAAATATAAAG
CTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTGTAACACTAAATATTTTAGTGTGAAATTGAATTTTTT
TATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTCACTTCTGTTCCTCCCTGCTTGCATTTTTTAAAAACT
AGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTGCTTTTAGTTTGTATGTTTAAGTGGTCAAGCAAGGCT
CTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAATGGGAGCAAAAGAGGCATTCCAGAAAGAAGAGTAGT
TAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTCTACACAAAGGTGTGATGGACACTGATGCTCTATTAA
GAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGGAAAGGGATATTTCATCATGACTGTTAAGAAAAGGTA
ACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATTTCTACTTGTTAAATAATTAAAAATCATCTTAAAATTCATACTTT
GACTTTAATTTAGACACAAGGAGATGTAATCGCTGTGTAACATCAGAGAAAGCTATATGGATTATCGTCAGAAGTAAATGTTTCTAACAT

>27084_27084_8_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000535753_ZNF451_chr6_57018659_ENST00000370706_length(amino acids)=849AA_BP=749
MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT
LSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD
RDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWV
VPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP
PSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLD
EMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI
NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDP
FKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKG
SDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTT

--------------------------------------------------------------
>27084_27084_9_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000535753_ZNF451_chr6_57018659_ENST00000491832_length(transcript)=2962nt_BP=2278nt
CCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCACTGGAAATTCGTTGTATGA
ATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAAAGAAGTCTGGCCTCTCGGA
CATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCTATGTTGCACTGAGACTGGT
GGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTCACGACACCAGCAGCCCTCT
GATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGATTTTTGAAAGCCTCTTGCC
CATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCCTGGGCAGGGTCTGGGACCT
CAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAGCCCTGGAGAAGGAGCCCGT
GCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCCCCGTCCTGCCTGCCAGCCC
CCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCCTGTCCCCCAAGCACAGCCT
CAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG
CTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTCCTTTCACCATCCTCTCAGGAGATCA
AGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTCACCACTTAGAGGGAGATATGATGTG
TGCCTTGTTAAATAGCATATCTGATACCACCAAAGGTACGCAGCTGCAGTCACAGTGCAAACCACCCAAGAGGAGGAGACTTCACTGCTG
AGAGAAACCAATAAACTGCTGTCCGCTAGTGAACTGTTGCCTGCTTGCTAAACCATCATGTTCTCTTACTTCTATCTTACTTATCTTTTT
TAAAAAAATCTCACTTTCATTCTTTAGTGTTTTAGAAGGAGGATGAATTCATAATAATTTTCTGGAGCTTTTTTTGATCTAGTAGATAAA
ATCTATATTGATGTATATAAAACATATATTCATGTGTTACAGTATGTTACTACAATTTTAAAAGCTCAGAATTCAGATCTTCACTTTGTT
TCTGAAATTCCAAGTTGACCTTCAGTTTTTTAGAAAGCAGTGCGCTTAGAGGTGAAAACCAGAAAGCAATAACAAAGGTGATCATTTAAG

>27084_27084_9_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000535753_ZNF451_chr6_57018659_ENST00000491832_length(amino acids)=829AA_BP=749
MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT
LSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD
RDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWV
VPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP
PSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLD
EMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI
NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDP
FKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKG
SDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIPFTILSGDQGFLELENQFKKTQRPAHILNPHHLEGDMMCALLNSISDTT

--------------------------------------------------------------
>27084_27084_10_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000594975_ZNF451_chr6_57018659_ENST00000357489_length(transcript)=4428nt_BP=2393nt
ACATGCGTGGCCCTGTCTACGGCCCCGCCCTCTCCCGGGACAGGCGGCCTGCGCACCGCCCTCCCGTCGTCCCAGTGCGCACGCGTGGCT
GCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCA
CTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAA
AGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCT
ATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTC
ACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGA
TTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCC
TGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAG
CCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCC
CCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCC
TGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCC
TGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAG
CACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGG
TCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCT
CTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGG
AACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCA
GTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGA
GCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCC
AGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAG
TCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCC
GCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCG
AAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACA
CGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGT
TCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCT
CTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGC
TCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAA
GTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTC
CTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTC
ACCACTTAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAACATGGGTGCCA
AAAATACTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGAAATGTAATTAA
AGATATTACCACACAACATCAAGTGGCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCAGAAATCCACTA
TTACAAATGTATTTGAAAACATGTTTTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGTGCAAACATGTA
CAGAAGAAATAGAATACATGTTCATGCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTTGAATTTATATA
TTTAGATTTAAAGGATTAAAAAAAAGGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTGTACTGTACAAA
TGATGCTAGTTTATTTTTTTAGCAGTGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTTCTCATGTGGCA
CTATTATATAATACCTTTGAGATCTTTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAAATTTTATCAGC
AATGTTCTTTGTGGGTGCCATGCATATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACCTTAATTTTTAA
GAAATAATTTAAATGAAACAATTTCCATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAAGGGAATGGTGT
CAGAATATTTGCATAAAATTATTTTTCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATAATGTTGAAAGC
CTACTCAGGAATAATCTTCCTTAACTCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATTGTCAGTTTCCT
TCATTTGGTATTACATATTTAATTCTTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGACTAAGAAGGGCT
TGTCATATTATCTTTGTGTATATGCTTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTATTTACCAAACT
TAAAAACATTTCTATAAATATAAAGCTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTGTAACACTAAAT
ATTTTAGTGTGAAATTGAATTTTTTTATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTCACTTCTGTTCC
TCCCTGCTTGCATTTTTTAAAAACTAGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTGCTTTTAGTTTG
TATGTTTAAGTGGTCAAGCAAGGCTCTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAATGGGAGCAAAA
GAGGCATTCCAGAAAGAAGAGTAGTTAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTCTACACAAAGGT
GTGATGGACACTGATGCTCTATTAAGAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGGAAAGGGATATT
TCATCATGACTGTTAAGAAAAGGTAACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATTTCTACTTGTTAAATAATTA

>27084_27084_10_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000594975_ZNF451_chr6_57018659_ENST00000357489_length(amino acids)=897AA_BP=797
MRGPVYGPALSRDRRPAHRPPVVPVRTRGCSPAPVPPALGARVRGKMAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLK
KSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGI
FESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVP
VLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLA
HIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLE
QDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQ
EDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSE
GVSLAERGSFGAMVKDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGS
ATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIP

--------------------------------------------------------------
>27084_27084_11_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000594975_ZNF451_chr6_57018659_ENST00000370706_length(transcript)=4534nt_BP=2393nt
ACATGCGTGGCCCTGTCTACGGCCCCGCCCTCTCCCGGGACAGGCGGCCTGCGCACCGCCCTCCCGTCGTCCCAGTGCGCACGCGTGGCT
GCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCA
CTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAA
AGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCT
ATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTC
ACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGA
TTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCC
TGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAG
CCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCC
CCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCC
TGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCC
TGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAG
CACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGG
TCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCT
CTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGG
AACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCA
GTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGA
GCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCC
AGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAG
TCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCC
GCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCG
AAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACA
CGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGT
TCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCT
CTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGC
TCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAA
GTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTC
CTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTC
ACCACTTAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGAATGTGACAGTGATGATAACATGGGTGCCA
AAAATACTTCAATAGGAGAAGAATTTATATCCACAGAAGATGTGGAATTAGAAGAAGCTATTAGAAGAAGTCTTGAGGAAATGTAATTAA
AGATATTACCACACAACATCAAGTGGCCTTGAAGAGACTGAGATAACGAATTCTTGAGTTTGTTTTCTAAAGGAGACCAGAAATCCACTA
TTACAAATGTATTTGAAAACATGTTTTTGCTTTCATATGTTCAAAATCTGATCTTTGTTTTGTATTTTTGTGCTAATGTGCAAACATGTA
CAGAAGAAATAGAATACATGTTCATGCAAATATAAATTATGTATTCTAATATAGGTGTAACAGTTTCCCAGTTAACTTTGAATTTATATA
TTTAGATTTAAAGGATTAAAAAAAAGGAAAGCTCTTGACAGTTGTTTCCCAAATAGCATTAGTTCTTTAATTTTATTTGTACTGTACAAA
TGATGCTAGTTTATTTTTTTAGCAGTGAAAATGAATATAAAAAAGGTGACATAGGTCAAGTTTTCCATAAATTCTACTTCTCATGTGGCA
CTATTATATAATACCTTTGAGATCTTTGTTTATGTTTATTAGAAGAGGGTAATGGAAACTGATCATGGAAACATTTAAAATTTTATCAGC
AATGTTCTTTGTGGGTGCCATGCATATGTAAATTATTGCTTTAATTAGAGCAGCACATTGCTAAAATAAAAAATACACCTTAATTTTTAA
GAAATAATTTAAATGAAACAATTTCCATTCCTTTTACCTGCTTAGACTTTTATGTGACTTGTATGGTCTCCTGGTTAAAGGGAATGGTGT
CAGAATATTTGCATAAAATTATTTTTCATAACAGTCCTTTTTTATATATTGGTGTAAACATAATATTCTTCAAGAAATAATGTTGAAAGC
CTACTCAGGAATAATCTTCCTTAACTCTTTAAATTTTTATTTCATGTGAAGTGTTTTCAGTTTAGTTATTCACTGAATTGTCAGTTTCCT
TCATTTGGTATTACATATTTAATTCTTAAATATTGAGGCCCCATTGTGAGTAATAAAAAATACGACATAAGTAGAAGACTAAGAAGGGCT
TGTCATATTATCTTTGTGTATATGCTTCATGTTATTTAACCAGAAATGTCTTATCTCTAAAAATTTTTAGTAGTAATTATTTACCAAACT
TAAAAACATTTCTATAAATATAAAGCTTTTCTTTATATTTAAGACAAAATATAAAGGCTAGAATTTGGTTCCTTCTCTGTAACACTAAAT
ATTTTAGTGTGAAATTGAATTTTTTTATTACTATAGTCTTTTCAATCTATAATTTGTGTTTTTAATTTCTTGATATGTCACTTCTGTTCC
TCCCTGCTTGCATTTTTTAAAAACTAGACATTGTGGCTTGAGAATTTATCAATCATCTTTCCGAAATGACCACATTGTGCTTTTAGTTTG
TATGTTTAAGTGGTCAAGCAAGGCTCTAGGAGGTAGTCACTGAGCTGGACCTTAAACACATCTGCAGGAGCTCACAAAATGGGAGCAAAA
GAGGCATTCCAGAAAGAAGAGTAGTTAAGCAGATGTGGGGGCAGGGCAAGAGGAGACAGCACCTTGTTGCCAGAGATTCTACACAAAGGT
GTGATGGACACTGATGCTCTATTAAGAAGCTTTTGTGGTGTGTGTGGTAGAGAATAATTAAGGCTTCTGATAAGACAGGAAAGGGATATT
TCATCATGACTGTTAAGAAAAGGTAACTGGGTTGTTTAATGTTTTAATTGATAATTGTCACTGATCGTATTTCTACTTGTTAAATAATTA
AAAATCATCTTAAAATTCATACTTTGACTTTAATTTAGACACAAGGAGATGTAATCGCTGTGTAACATCAGAGAAAGCTATATGGATTAT

>27084_27084_11_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000594975_ZNF451_chr6_57018659_ENST00000370706_length(amino acids)=897AA_BP=797
MRGPVYGPALSRDRRPAHRPPVVPVRTRGCSPAPVPPALGARVRGKMAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLK
KSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGI
FESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVP
VLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLA
HIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLE
QDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQ
EDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSE
GVSLAERGSFGAMVKDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGS
ATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIP

--------------------------------------------------------------
>27084_27084_12_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000594975_ZNF451_chr6_57018659_ENST00000491832_length(transcript)=3077nt_BP=2393nt
ACATGCGTGGCCCTGTCTACGGCCCCGCCCTCTCCCGGGACAGGCGGCCTGCGCACCGCCCTCCCGTCGTCCCAGTGCGCACGCGTGGCT
GCAGCCCCGCCCCCGTTCCCCCGGCGCTCGGAGCCCGAGTCCGCGGGAAGATGGCGGCGCCGCTCATCCCCCTCTCCCAGCAGATTCCCA
CTGGAAATTCGTTGTATGAATCTTATTACAAGCAGGTCGATCCGGCATACACAGGGAGGGTGGGGGCGAGTGAAGCTGCGCTTTTTCTAA
AGAAGTCTGGCCTCTCGGACATTATCCTTGGGAAGATATGGGACTTGGCCGATCCAGAAGGTAAAGGGTTCTTGGACAAACAGGGTTTCT
ATGTTGCACTGAGACTGGTGGCCTGTGCACAGAGTGGCCATGAAGTTACCTTGAGCAATCTGAATTTGAGCATGCCACCGCCTAAATTTC
ACGACACCAGCAGCCCTCTGATGGTCACACCGCCCTCTGCAGAGGCCCACTGGGCTGTGAGGGTGGAAGAAAAGGCCAAATTTGATGGGA
TTTTTGAAAGCCTCTTGCCCATCAATGGTTTGCTCTCTGGAGACAAAGTCAAGCCAGTCCTCATGAACTCAAAGCTGCCTCTTGATGTCC
TGGGCAGGGTCTGGGACCTCAGTGACATTGACAAGGATGGGCACTTGGATCGAGATGAGTTCGCTGTGGCCATGCACTTGGTGTACCGAG
CCCTGGAGAAGGAGCCCGTGCCCTCCGCCCTGCCCCCGTCCCTCATCCCACCCTCCAAGAGAAAGAAGACTGTGTTCCCTGGCGCCGTCC
CCGTCCTGCCTGCCAGCCCCCCACCAAAAGACAGCCTCCGCTCCACGCCGTCCCACGGCAGCGTCAGCAGCCTCAACAGCACAGGGAGCC
TGTCCCCCAAGCACAGCCTCAAGCAAACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCC
TGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAG
CACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGG
TCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCT
CTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGG
AACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCA
GTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGA
GCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCC
AGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAG
TCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCC
GCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCG
AAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACA
CGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGT
TCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCT
CTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGC
TCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAA
GTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGCTGGCCGTCTAGATGAACAACTACCCAAGCAAATTC
CTTTCACCATCCTCTCAGGAGATCAAGGTTTTCTGGAGCTAGAGAATCAATTTAAGAAGACTCAGAGGCCAGCTCATATACTAAACCCTC
ACCACTTAGAGGGAGATATGATGTGTGCCTTGTTAAATAGCATATCTGATACCACCAAAGGTACGCAGCTGCAGTCACAGTGCAAACCAC
CCAAGAGGAGGAGACTTCACTGCTGAGAGAAACCAATAAACTGCTGTCCGCTAGTGAACTGTTGCCTGCTTGCTAAACCATCATGTTCTC
TTACTTCTATCTTACTTATCTTTTTTAAAAAAATCTCACTTTCATTCTTTAGTGTTTTAGAAGGAGGATGAATTCATAATAATTTTCTGG
AGCTTTTTTTGATCTAGTAGATAAAATCTATATTGATGTATATAAAACATATATTCATGTGTTACAGTATGTTACTACAATTTTAAAAGC
TCAGAATTCAGATCTTCACTTTGTTTCTGAAATTCCAAGTTGACCTTCAGTTTTTTAGAAAGCAGTGCGCTTAGAGGTGAAAACCAGAAA
GCAATAACAAAGGTGATCATTTAAGAGGTTGACAGTGACAAAATAAAACGCTGATAGGCTTTTAGGTCCTTAGAGAAGTGGGTACATCCT

>27084_27084_12_EPS15L1-ZNF451_EPS15L1_chr19_16495940_ENST00000594975_ZNF451_chr6_57018659_ENST00000491832_length(amino acids)=877AA_BP=797
MRGPVYGPALSRDRRPAHRPPVVPVRTRGCSPAPVPPALGARVRGKMAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLK
KSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGI
FESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVP
VLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLA
HIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLE
QDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQ
EDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSE
GVSLAERGSFGAMVKDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGS
ATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKAGRLDEQLPKQIP

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Fusion Gene PPI Analysis for EPS15L1-ZNF451


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000248070-212315_368749.0865.0DAB2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000455140-212415_368749.0911.0DAB2
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000535753-212215_368749.0755.0DAB2
TgeneZNF451chr19:16495940chr6:57018659ENST000003707080430_370560.0SUMO2 1
TgeneZNF451chr19:16495940chr6:57018659ENST000003707080442_500560.0SUMO2 2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneEPS15L1chr19:16495940chr6:57018659ENST00000597937-11615_3680602.0DAB2
TgeneZNF451chr19:16495940chr6:57018659ENST00000357489101430_37913.01014.0SUMO2 1
TgeneZNF451chr19:16495940chr6:57018659ENST00000370706111530_37961.01062.0SUMO2 1
TgeneZNF451chr19:16495940chr6:57018659ENST00000357489101442_50913.01014.0SUMO2 2
TgeneZNF451chr19:16495940chr6:57018659ENST00000370706111542_50961.01062.0SUMO2 2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EPS15L1-ZNF451


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EPS15L1-ZNF451


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource