FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ERC1-GPC5 (FusionGDB2 ID:27263)

Fusion Gene Summary for ERC1-GPC5

check button Fusion gene summary
Fusion gene informationFusion gene name: ERC1-GPC5
Fusion gene ID: 27263
HgeneTgene
Gene symbol

ERC1

GPC5

Gene ID

23085

2262

Gene nameELKS/RAB6-interacting/CAST family member 1glypican 5
SynonymsCast2|ELKS|ERC-1|RAB6IP2-
Cytomap

12p13.33

13q31.3

Type of geneprotein-codingprotein-coding
DescriptionELKS/Rab6-interacting/CAST family member 1RAB6 interacting protein 2glypican-5bA93M14.1glypican proteoglycan 5
Modification date2020031320200313
UniProtAcc

Q8IUD2

P78333

Ensembl transtripts involved in fusion geneENST00000536573, ENST00000355446, 
ENST00000360905, ENST00000397203, 
ENST00000543086, ENST00000546231, 
ENST00000589028, 		ENST00000377067, 
ENST00000483422, 
Fusion gene scores* DoF score32 X 23 X 16=1177618 X 14 X 8=2016
# samples 3820
** MAII scorelog2(38/11776*10)=-4.95370634772607
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/2016*10)=-3.33342373372519
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ERC1 [Title/Abstract] AND GPC5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointERC1(1250953)-GPC5(93518535), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneERC1

GO:0007252

I-kappaB phosphorylation

15218148


check buttonFusion gene breakpoints across ERC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GPC5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4READTCGA-F5-6864-01AERC1chr12

1250953

-GPC5chr13

93518535

+


Top

Fusion Gene ORF analysis for ERC1-GPC5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000536573ENST00000377067ERC1chr12

1250953

-GPC5chr13

93518535

+
3UTR-intronENST00000536573ENST00000483422ERC1chr12

1250953

-GPC5chr13

93518535

+
5CDS-intronENST00000355446ENST00000483422ERC1chr12

1250953

-GPC5chr13

93518535

+
5CDS-intronENST00000360905ENST00000483422ERC1chr12

1250953

-GPC5chr13

93518535

+
5CDS-intronENST00000397203ENST00000483422ERC1chr12

1250953

-GPC5chr13

93518535

+
5CDS-intronENST00000543086ENST00000483422ERC1chr12

1250953

-GPC5chr13

93518535

+
5CDS-intronENST00000546231ENST00000483422ERC1chr12

1250953

-GPC5chr13

93518535

+
5CDS-intronENST00000589028ENST00000483422ERC1chr12

1250953

-GPC5chr13

93518535

+
In-frameENST00000355446ENST00000377067ERC1chr12

1250953

-GPC5chr13

93518535

+
In-frameENST00000360905ENST00000377067ERC1chr12

1250953

-GPC5chr13

93518535

+
In-frameENST00000397203ENST00000377067ERC1chr12

1250953

-GPC5chr13

93518535

+
In-frameENST00000543086ENST00000377067ERC1chr12

1250953

-GPC5chr13

93518535

+
In-frameENST00000546231ENST00000377067ERC1chr12

1250953

-GPC5chr13

93518535

+
In-frameENST00000589028ENST00000377067ERC1chr12

1250953

-GPC5chr13

93518535

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000543086ERC1chr121250953-ENST00000377067GPC5chr1393518535+288019242711941556
ENST00000546231ERC1chr121250953-ENST00000377067GPC5chr1393518535+322122655282282584
ENST00000397203ERC1chr121250953-ENST00000377067GPC5chr1393518535+309921434062160584
ENST00000360905ERC1chr121250953-ENST00000377067GPC5chr1393518535+287419181811935584
ENST00000589028ERC1chr121250953-ENST00000377067GPC5chr1393518535+285018941571911584
ENST00000355446ERC1chr121250953-ENST00000377067GPC5chr1393518535+282518691321886584

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000543086ENST00000377067ERC1chr121250953-GPC5chr1393518535+0.0012779980.998722
ENST00000546231ENST00000377067ERC1chr121250953-GPC5chr1393518535+0.001888620.99811137
ENST00000397203ENST00000377067ERC1chr121250953-GPC5chr1393518535+0.0019529640.998047
ENST00000360905ENST00000377067ERC1chr121250953-GPC5chr1393518535+0.0016898280.9983102
ENST00000589028ENST00000377067ERC1chr121250953-GPC5chr1393518535+0.0015345980.9984654
ENST00000355446ENST00000377067ERC1chr121250953-GPC5chr1393518535+0.0016129780.998387

Top

Fusion Genomic Features for ERC1-GPC5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ERC1-GPC5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:1250953/chr13:93518535)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ERC1

Q8IUD2

GPC5

P78333

FUNCTION: Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. {ECO:0000269|PubMed:15218148}.FUNCTION: Cell surface proteoglycan that bears heparan sulfate. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERC1chr12:1250953chr13:93518535ENST00000360905-8191060_11005791117.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000360905-819144_9885791117.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000397203-8191060_11005791117.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000397203-819144_9885791117.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000543086-7181060_11005511089.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000543086-718144_9885511089.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000589028-7181060_11005791117.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000589028-718144_9885791117.0Coiled coilOntology_term=ECO:0000255
HgeneERC1chr12:1250953chr13:93518535ENST00000360905-8191046_11085791117.0DomainFIP-RBD
HgeneERC1chr12:1250953chr13:93518535ENST00000397203-8191046_11085791117.0DomainFIP-RBD
HgeneERC1chr12:1250953chr13:93518535ENST00000543086-7181046_11085511089.0DomainFIP-RBD
HgeneERC1chr12:1250953chr13:93518535ENST00000589028-7181046_11085791117.0DomainFIP-RBD


Top

Fusion Gene Sequence for ERC1-GPC5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27263_27263_1_ERC1-GPC5_ERC1_chr12_1250953_ENST00000355446_GPC5_chr13_93518535_ENST00000377067_length(transcript)=2825nt_BP=1869nt
GATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGT
TGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAG
AGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTT
GGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGAC
CATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCT
ATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCA
TCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGAT
CTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAG
GAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAG
ATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAA
CCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAG
ACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTG
CAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTA
GAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGAGATGCATCGAAGGTTTGAGAATGCTCCTGATTCTGCCAAA
ACAAAAGCTCTGCAAACTGTTATTGAGATGAAGGATTCAAAAATTTCCTCTATGGAGCGTGGGCTTCGAGACCTGGAAGAGGAAATTCAG
ATGCTGAAATCGAATGGTGCTTTGAGTACTGAGGAAAGGGAAGAAGAAATGAAGCAAATGGAAGTGTATCGGAGCCATTCTAAATTTATG
AAAAATAAGGTAGAACAACTGAAGGAGGAACTAAGTTCGAAAGAGGCTCAATGGGAGGAGCTGAAAAAGAAAGCGGCTGGTCTTCAGGCT
GAGATTGGCCAGGTGAAACAGGAGCTGTCCAGAAAGGACACAGAACTACTCGCCCTGCAGACAAAGCTAGAAACACTCACAAACCAGTTC
TCAGATAGTAAACAGCACATTGAAGTGTTGAAGGAGTCCTTGACTGCTAAGGAGCAGAGGGCTGCCATCCTGCAGACTGAGGTGGATGCT
CTCCGATTGCGTTTGGAAGAGAAGGAAACCATGTTGAATAAAAAGACAAAACAAATTCAGGATATGGCTGAAGAGAAGGGGACACAAGCT
GGAGAGATACATGACCTCAAGGACATGTTGGATGTGAAGGAGCGGAAGGTTAATGTTCTTCAGAAGAAGGGATGCCAGATGATATGAACT
TCAGTGATGTAAAGCAAATCCATCAAACAGACACTGGCAGTACTTTAGACACAACAGGAGCAGGATGTGCAGTGGCGACTGAATCTATGA
CATTCACTCTGATAAGTGTGGTGATGTTACTTCCCGGGATTTGGTAACTGAACTCTTCTGTCCTGACATACCTTACTGAAGTCTCGATTT
CTTCTCTCTCTGCATATGCCTGGAATAAGAGATCCTTTTTCAATGTAACAATTATATTTATGAAAAGATATGTTACACTAACTTCTCAGA
AGCCAAGCTGAAATATTCATAAAGTCCCTAAAACTCAACGTTTAAATGACACACTTTAAAAATATGTCTTTTTTCAATCTAACTGAAAAC
CTTCTTAACTTCTAATATATTAAATCTGAAGATGTGAAGGGCACAGAAGTGACTTTGAATAAGAAGAATTTAGTGTATCTGTAATTTTAT
TATCAATTCCAAGCCCCTTCCTTTCTAAATTAAAAATGTTTTCATTTGAAAGTGTATTTGCCAGACAATGAAAACAGTATGCAGTATTTC
TTAAAGTATTGAAATTAGAATATCATGAAATAAATCAAAACATACAATGGCAAGTAGTATGCATGCATATTCAAGAGACTCTTCCATTTT
TGCAAGCTGTAGAAGGAAATGTCTGAATGTCTATAAGTTATGGGGTAGATTCTTGAGAAGCATTTCATATAATTTCACTGAAGAACCTTG
ATAATTTTGACCCACTGTAACTTAGCCACTGATGAACCTTAAAGCTGAGTATTTTATTAACACCTGATTTGTATTCCATTATATTCAAAA
TGCATCTTTGGTATTGTGCCTCTGCTCCCATCTCTCTCTTTGCCTCATAGATTTAGCTATGTTGGGAAGCACATGCTTGCTCTAGGAATA

>27263_27263_1_ERC1-GPC5_ERC1_chr12_1250953_ENST00000355446_GPC5_chr13_93518535_ENST00000377067_length(amino acids)=584AA_BP=
MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT
LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL
HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSK
EAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK

--------------------------------------------------------------
>27263_27263_2_ERC1-GPC5_ERC1_chr12_1250953_ENST00000360905_GPC5_chr13_93518535_ENST00000377067_length(transcript)=2874nt_BP=1918nt
AGCAGTAGCGGCAGCCCTGAGGACGATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACC
AACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAAC
CATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTT
GGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACA
ATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGAC
ACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAG
TGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACAC
AATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAG
TTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCAT
TTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAG
GGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCT
TCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCA
GACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCA
TGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTT
GAGAGAGGAGATGCATCGAAGGTTTGAGAATGCTCCTGATTCTGCCAAAACAAAAGCTCTGCAAACTGTTATTGAGATGAAGGATTCAAA
AATTTCCTCTATGGAGCGTGGGCTTCGAGACCTGGAAGAGGAAATTCAGATGCTGAAATCGAATGGTGCTTTGAGTACTGAGGAAAGGGA
AGAAGAAATGAAGCAAATGGAAGTGTATCGGAGCCATTCTAAATTTATGAAAAATAAGGTAGAACAACTGAAGGAGGAACTAAGTTCGAA
AGAGGCTCAATGGGAGGAGCTGAAAAAGAAAGCGGCTGGTCTTCAGGCTGAGATTGGCCAGGTGAAACAGGAGCTGTCCAGAAAGGACAC
AGAACTACTCGCCCTGCAGACAAAGCTAGAAACACTCACAAACCAGTTCTCAGATAGTAAACAGCACATTGAAGTGTTGAAGGAGTCCTT
GACTGCTAAGGAGCAGAGGGCTGCCATCCTGCAGACTGAGGTGGATGCTCTCCGATTGCGTTTGGAAGAGAAGGAAACCATGTTGAATAA
AAAGACAAAACAAATTCAGGATATGGCTGAAGAGAAGGGGACACAAGCTGGAGAGATACATGACCTCAAGGACATGTTGGATGTGAAGGA
GCGGAAGGTTAATGTTCTTCAGAAGAAGGGATGCCAGATGATATGAACTTCAGTGATGTAAAGCAAATCCATCAAACAGACACTGGCAGT
ACTTTAGACACAACAGGAGCAGGATGTGCAGTGGCGACTGAATCTATGACATTCACTCTGATAAGTGTGGTGATGTTACTTCCCGGGATT
TGGTAACTGAACTCTTCTGTCCTGACATACCTTACTGAAGTCTCGATTTCTTCTCTCTCTGCATATGCCTGGAATAAGAGATCCTTTTTC
AATGTAACAATTATATTTATGAAAAGATATGTTACACTAACTTCTCAGAAGCCAAGCTGAAATATTCATAAAGTCCCTAAAACTCAACGT
TTAAATGACACACTTTAAAAATATGTCTTTTTTCAATCTAACTGAAAACCTTCTTAACTTCTAATATATTAAATCTGAAGATGTGAAGGG
CACAGAAGTGACTTTGAATAAGAAGAATTTAGTGTATCTGTAATTTTATTATCAATTCCAAGCCCCTTCCTTTCTAAATTAAAAATGTTT
TCATTTGAAAGTGTATTTGCCAGACAATGAAAACAGTATGCAGTATTTCTTAAAGTATTGAAATTAGAATATCATGAAATAAATCAAAAC
ATACAATGGCAAGTAGTATGCATGCATATTCAAGAGACTCTTCCATTTTTGCAAGCTGTAGAAGGAAATGTCTGAATGTCTATAAGTTAT
GGGGTAGATTCTTGAGAAGCATTTCATATAATTTCACTGAAGAACCTTGATAATTTTGACCCACTGTAACTTAGCCACTGATGAACCTTA
AAGCTGAGTATTTTATTAACACCTGATTTGTATTCCATTATATTCAAAATGCATCTTTGGTATTGTGCCTCTGCTCCCATCTCTCTCTTT

>27263_27263_2_ERC1-GPC5_ERC1_chr12_1250953_ENST00000360905_GPC5_chr13_93518535_ENST00000377067_length(amino acids)=584AA_BP=
MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT
LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL
HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSK
EAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK

--------------------------------------------------------------
>27263_27263_3_ERC1-GPC5_ERC1_chr12_1250953_ENST00000397203_GPC5_chr13_93518535_ENST00000377067_length(transcript)=3099nt_BP=2143nt
GTGCTGTGGCGGCGGCGGCGGCGGTAGTGGCGGCGGCGGCGGTGCCTGGGCGGCAGCAGCAGCAGTAGCGGCAGCCCTGAGGACGGTGAG
ACGGCCGCGGCGGCGGCGACAGCGCGGAAGTCGCGCGGGACCCAGAGCTTCCCCCCTGTCGCTAGTGCTGAGGCTTTCGCCTTTCCTACC
CAGCTTCTTGCTCACGGCCCGGGCTGGGCTGGGCAGGGCAACGCGCCCCCGGGGAGGGGCGGAGCTGTAGATATGGTGTAAGATACTTCT
TCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTG
TTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAG
CCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAG
TGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAG
TGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGAC
TGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTAT
GGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAA
TGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAA
GAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACAT
GCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGG
CGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCG
AAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAAT
GTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCA
CCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGAGATGCATCGAAGGTTTGAGAATGCTCCTGATTCTGC
CAAAACAAAAGCTCTGCAAACTGTTATTGAGATGAAGGATTCAAAAATTTCCTCTATGGAGCGTGGGCTTCGAGACCTGGAAGAGGAAAT
TCAGATGCTGAAATCGAATGGTGCTTTGAGTACTGAGGAAAGGGAAGAAGAAATGAAGCAAATGGAAGTGTATCGGAGCCATTCTAAATT
TATGAAAAATAAGGTAGAACAACTGAAGGAGGAACTAAGTTCGAAAGAGGCTCAATGGGAGGAGCTGAAAAAGAAAGCGGCTGGTCTTCA
GGCTGAGATTGGCCAGGTGAAACAGGAGCTGTCCAGAAAGGACACAGAACTACTCGCCCTGCAGACAAAGCTAGAAACACTCACAAACCA
GTTCTCAGATAGTAAACAGCACATTGAAGTGTTGAAGGAGTCCTTGACTGCTAAGGAGCAGAGGGCTGCCATCCTGCAGACTGAGGTGGA
TGCTCTCCGATTGCGTTTGGAAGAGAAGGAAACCATGTTGAATAAAAAGACAAAACAAATTCAGGATATGGCTGAAGAGAAGGGGACACA
AGCTGGAGAGATACATGACCTCAAGGACATGTTGGATGTGAAGGAGCGGAAGGTTAATGTTCTTCAGAAGAAGGGATGCCAGATGATATG
AACTTCAGTGATGTAAAGCAAATCCATCAAACAGACACTGGCAGTACTTTAGACACAACAGGAGCAGGATGTGCAGTGGCGACTGAATCT
ATGACATTCACTCTGATAAGTGTGGTGATGTTACTTCCCGGGATTTGGTAACTGAACTCTTCTGTCCTGACATACCTTACTGAAGTCTCG
ATTTCTTCTCTCTCTGCATATGCCTGGAATAAGAGATCCTTTTTCAATGTAACAATTATATTTATGAAAAGATATGTTACACTAACTTCT
CAGAAGCCAAGCTGAAATATTCATAAAGTCCCTAAAACTCAACGTTTAAATGACACACTTTAAAAATATGTCTTTTTTCAATCTAACTGA
AAACCTTCTTAACTTCTAATATATTAAATCTGAAGATGTGAAGGGCACAGAAGTGACTTTGAATAAGAAGAATTTAGTGTATCTGTAATT
TTATTATCAATTCCAAGCCCCTTCCTTTCTAAATTAAAAATGTTTTCATTTGAAAGTGTATTTGCCAGACAATGAAAACAGTATGCAGTA
TTTCTTAAAGTATTGAAATTAGAATATCATGAAATAAATCAAAACATACAATGGCAAGTAGTATGCATGCATATTCAAGAGACTCTTCCA
TTTTTGCAAGCTGTAGAAGGAAATGTCTGAATGTCTATAAGTTATGGGGTAGATTCTTGAGAAGCATTTCATATAATTTCACTGAAGAAC
CTTGATAATTTTGACCCACTGTAACTTAGCCACTGATGAACCTTAAAGCTGAGTATTTTATTAACACCTGATTTGTATTCCATTATATTC
AAAATGCATCTTTGGTATTGTGCCTCTGCTCCCATCTCTCTCTTTGCCTCATAGATTTAGCTATGTTGGGAAGCACATGCTTGCTCTAGG

>27263_27263_3_ERC1-GPC5_ERC1_chr12_1250953_ENST00000397203_GPC5_chr13_93518535_ENST00000377067_length(amino acids)=584AA_BP=
MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT
LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL
HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSK
EAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK

--------------------------------------------------------------
>27263_27263_4_ERC1-GPC5_ERC1_chr12_1250953_ENST00000543086_GPC5_chr13_93518535_ENST00000377067_length(transcript)=2880nt_BP=1924nt
GGGCGCGGTGACGTCGCGGGCGCCTGGGCCGTGCTGTGGCGGCGGCGGCGGCGGTAGTGGCGGCGGCGGCGGTGCCTGGGCGGCAGCAGC
AGCAGTAGCGGCAGCCCTGAGGACGATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACC
AACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAAC
CATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTT
GGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACA
ATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGAC
ACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAG
TGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACAC
AATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAG
TTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCAT
TTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAG
GGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCT
TCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCA
GACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCA
TGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTT
GAGAGAGGAGATGCATCGAAGGTTTGAGAATGCTCCTGATTCTGCCAAAACAAAAGCTCTGCAAACTGTTATTGAGATGAAGGATTCAAA
AATTTCCTCTATGGAGCGTGGGCTTCGAGACCTGGAAGAGGAAATTCAGATGCTGAAATCGAATGGTGCTTTGAGTACTGAGGAAAGGGA
AGAAGAAATGAAGCAAATGGAAGTGTATCGGAGCCATTCTAAATTTATGAAAAATAAGATTGGCCAGGTGAAACAGGAGCTGTCCAGAAA
GGACACAGAACTACTCGCCCTGCAGACAAAGCTAGAAACACTCACAAACCAGTTCTCAGATAGTAAACAGCACATTGAAGTGTTGAAGGA
GTCCTTGACTGCTAAGGAGCAGAGGGCTGCCATCCTGCAGACTGAGGTGGATGCTCTCCGATTGCGTTTGGAAGAGAAGGAAACCATGTT
GAATAAAAAGACAAAACAAATTCAGGATATGGCTGAAGAGAAGGGGACACAAGCTGGAGAGATACATGACCTCAAGGACATGTTGGATGT
GAAGGAGCGGAAGGTTAATGTTCTTCAGAAGAAGGGATGCCAGATGATATGAACTTCAGTGATGTAAAGCAAATCCATCAAACAGACACT
GGCAGTACTTTAGACACAACAGGAGCAGGATGTGCAGTGGCGACTGAATCTATGACATTCACTCTGATAAGTGTGGTGATGTTACTTCCC
GGGATTTGGTAACTGAACTCTTCTGTCCTGACATACCTTACTGAAGTCTCGATTTCTTCTCTCTCTGCATATGCCTGGAATAAGAGATCC
TTTTTCAATGTAACAATTATATTTATGAAAAGATATGTTACACTAACTTCTCAGAAGCCAAGCTGAAATATTCATAAAGTCCCTAAAACT
CAACGTTTAAATGACACACTTTAAAAATATGTCTTTTTTCAATCTAACTGAAAACCTTCTTAACTTCTAATATATTAAATCTGAAGATGT
GAAGGGCACAGAAGTGACTTTGAATAAGAAGAATTTAGTGTATCTGTAATTTTATTATCAATTCCAAGCCCCTTCCTTTCTAAATTAAAA
ATGTTTTCATTTGAAAGTGTATTTGCCAGACAATGAAAACAGTATGCAGTATTTCTTAAAGTATTGAAATTAGAATATCATGAAATAAAT
CAAAACATACAATGGCAAGTAGTATGCATGCATATTCAAGAGACTCTTCCATTTTTGCAAGCTGTAGAAGGAAATGTCTGAATGTCTATA
AGTTATGGGGTAGATTCTTGAGAAGCATTTCATATAATTTCACTGAAGAACCTTGATAATTTTGACCCACTGTAACTTAGCCACTGATGA
ACCTTAAAGCTGAGTATTTTATTAACACCTGATTTGTATTCCATTATATTCAAAATGCATCTTTGGTATTGTGCCTCTGCTCCCATCTCT
CTCTTTGCCTCATAGATTTAGCTATGTTGGGAAGCACATGCTTGCTCTAGGAATATCTCCAATAAAGCTGTTAACTATTTGGTGGAAAAA

>27263_27263_4_ERC1-GPC5_ERC1_chr12_1250953_ENST00000543086_GPC5_chr13_93518535_ENST00000377067_length(amino acids)=556AA_BP=
MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT
LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL
HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRK
DTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV

--------------------------------------------------------------
>27263_27263_5_ERC1-GPC5_ERC1_chr12_1250953_ENST00000546231_GPC5_chr13_93518535_ENST00000377067_length(transcript)=3221nt_BP=2265nt
GGGCCGTGCTGTGGCGGCGGCGGCGGCGGTAGTGGCGGCGGCGGCGGTGCCTGGGCGGCAGCAGCAGCAGTAGCGGCAGCCCTGAGGACG
GTGAGACGGCCGCGGCGGCGGCGACAGCGCGGAAGTCGCGCGGGACCCAGAGCTTCCCCCCTGTCGCTAGTGCTGAGGCTTTCGCCTTTC
CTACCCAGCTTCTTGCTCACGGCCCGGGCTGGGCTGGGCAGGGCAACGCGCCCCCGGGGAGGGGCGGAGCTGTAGGTTGGTCTTGAACTC
CTGGCCTCAAGCGATCTTCCTACCTTGGCCTCCCAGAGCGCTGGGATTATAGGCATGAGCCATTGCACTTGGCACTTTTTTTGTTTGTTT
TCCAGTTGCATGATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCAT
AGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGT
GCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGA
ACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCT
GCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCT
GGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCA
TTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTG
CAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAAT
AGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAG
TACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAG
CTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCAT
GAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCT
CGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGA
CGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGAGATG
CATCGAAGGTTTGAGAATGCTCCTGATTCTGCCAAAACAAAAGCTCTGCAAACTGTTATTGAGATGAAGGATTCAAAAATTTCCTCTATG
GAGCGTGGGCTTCGAGACCTGGAAGAGGAAATTCAGATGCTGAAATCGAATGGTGCTTTGAGTACTGAGGAAAGGGAAGAAGAAATGAAG
CAAATGGAAGTGTATCGGAGCCATTCTAAATTTATGAAAAATAAGGTAGAACAACTGAAGGAGGAACTAAGTTCGAAAGAGGCTCAATGG
GAGGAGCTGAAAAAGAAAGCGGCTGGTCTTCAGGCTGAGATTGGCCAGGTGAAACAGGAGCTGTCCAGAAAGGACACAGAACTACTCGCC
CTGCAGACAAAGCTAGAAACACTCACAAACCAGTTCTCAGATAGTAAACAGCACATTGAAGTGTTGAAGGAGTCCTTGACTGCTAAGGAG
CAGAGGGCTGCCATCCTGCAGACTGAGGTGGATGCTCTCCGATTGCGTTTGGAAGAGAAGGAAACCATGTTGAATAAAAAGACAAAACAA
ATTCAGGATATGGCTGAAGAGAAGGGGACACAAGCTGGAGAGATACATGACCTCAAGGACATGTTGGATGTGAAGGAGCGGAAGGTTAAT
GTTCTTCAGAAGAAGGGATGCCAGATGATATGAACTTCAGTGATGTAAAGCAAATCCATCAAACAGACACTGGCAGTACTTTAGACACAA
CAGGAGCAGGATGTGCAGTGGCGACTGAATCTATGACATTCACTCTGATAAGTGTGGTGATGTTACTTCCCGGGATTTGGTAACTGAACT
CTTCTGTCCTGACATACCTTACTGAAGTCTCGATTTCTTCTCTCTCTGCATATGCCTGGAATAAGAGATCCTTTTTCAATGTAACAATTA
TATTTATGAAAAGATATGTTACACTAACTTCTCAGAAGCCAAGCTGAAATATTCATAAAGTCCCTAAAACTCAACGTTTAAATGACACAC
TTTAAAAATATGTCTTTTTTCAATCTAACTGAAAACCTTCTTAACTTCTAATATATTAAATCTGAAGATGTGAAGGGCACAGAAGTGACT
TTGAATAAGAAGAATTTAGTGTATCTGTAATTTTATTATCAATTCCAAGCCCCTTCCTTTCTAAATTAAAAATGTTTTCATTTGAAAGTG
TATTTGCCAGACAATGAAAACAGTATGCAGTATTTCTTAAAGTATTGAAATTAGAATATCATGAAATAAATCAAAACATACAATGGCAAG
TAGTATGCATGCATATTCAAGAGACTCTTCCATTTTTGCAAGCTGTAGAAGGAAATGTCTGAATGTCTATAAGTTATGGGGTAGATTCTT
GAGAAGCATTTCATATAATTTCACTGAAGAACCTTGATAATTTTGACCCACTGTAACTTAGCCACTGATGAACCTTAAAGCTGAGTATTT
TATTAACACCTGATTTGTATTCCATTATATTCAAAATGCATCTTTGGTATTGTGCCTCTGCTCCCATCTCTCTCTTTGCCTCATAGATTT

>27263_27263_5_ERC1-GPC5_ERC1_chr12_1250953_ENST00000546231_GPC5_chr13_93518535_ENST00000377067_length(amino acids)=584AA_BP=
MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT
LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL
HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSK
EAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK

--------------------------------------------------------------
>27263_27263_6_ERC1-GPC5_ERC1_chr12_1250953_ENST00000589028_GPC5_chr13_93518535_ENST00000377067_length(transcript)=2850nt_BP=1894nt
GATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCATAGAGACACCTC
ACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGTGCCCGCTCTGT
TGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGAACCAACAGTAC
GGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCTGCCTATGCCAC
CTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCTGGGGGACGTCT
GCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCATTTGGAGAGCA
TCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTGCAGACACAGCT
GAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAATAGCATCAAGAC
CTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAGTACAGAGTTGT
ACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAGCTGTTTCAGCA
GGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCATGAGCGGCAGGC
CAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCTCGGGATGAATC
CATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGACGACTGGCAGA
GGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGAGATGCATCGAAGGTT
TGAGAATGCTCCTGATTCTGCCAAAACAAAAGCTCTGCAAACTGTTATTGAGATGAAGGATTCAAAAATTTCCTCTATGGAGCGTGGGCT
TCGAGACCTGGAAGAGGAAATTCAGATGCTGAAATCGAATGGTGCTTTGAGTACTGAGGAAAGGGAAGAAGAAATGAAGCAAATGGAAGT
GTATCGGAGCCATTCTAAATTTATGAAAAATAAGGTAGAACAACTGAAGGAGGAACTAAGTTCGAAAGAGGCTCAATGGGAGGAGCTGAA
AAAGAAAGCGGCTGGTCTTCAGGCTGAGATTGGCCAGGTGAAACAGGAGCTGTCCAGAAAGGACACAGAACTACTCGCCCTGCAGACAAA
GCTAGAAACACTCACAAACCAGTTCTCAGATAGTAAACAGCACATTGAAGTGTTGAAGGAGTCCTTGACTGCTAAGGAGCAGAGGGCTGC
CATCCTGCAGACTGAGGTGGATGCTCTCCGATTGCGTTTGGAAGAGAAGGAAACCATGTTGAATAAAAAGACAAAACAAATTCAGGATAT
GGCTGAAGAGAAGGGGACACAAGCTGGAGAGATACATGACCTCAAGGACATGTTGGATGTGAAGGAGCGGAAGGTTAATGTTCTTCAGAA
GAAGGGATGCCAGATGATATGAACTTCAGTGATGTAAAGCAAATCCATCAAACAGACACTGGCAGTACTTTAGACACAACAGGAGCAGGA
TGTGCAGTGGCGACTGAATCTATGACATTCACTCTGATAAGTGTGGTGATGTTACTTCCCGGGATTTGGTAACTGAACTCTTCTGTCCTG
ACATACCTTACTGAAGTCTCGATTTCTTCTCTCTCTGCATATGCCTGGAATAAGAGATCCTTTTTCAATGTAACAATTATATTTATGAAA
AGATATGTTACACTAACTTCTCAGAAGCCAAGCTGAAATATTCATAAAGTCCCTAAAACTCAACGTTTAAATGACACACTTTAAAAATAT
GTCTTTTTTCAATCTAACTGAAAACCTTCTTAACTTCTAATATATTAAATCTGAAGATGTGAAGGGCACAGAAGTGACTTTGAATAAGAA
GAATTTAGTGTATCTGTAATTTTATTATCAATTCCAAGCCCCTTCCTTTCTAAATTAAAAATGTTTTCATTTGAAAGTGTATTTGCCAGA
CAATGAAAACAGTATGCAGTATTTCTTAAAGTATTGAAATTAGAATATCATGAAATAAATCAAAACATACAATGGCAAGTAGTATGCATG
CATATTCAAGAGACTCTTCCATTTTTGCAAGCTGTAGAAGGAAATGTCTGAATGTCTATAAGTTATGGGGTAGATTCTTGAGAAGCATTT
CATATAATTTCACTGAAGAACCTTGATAATTTTGACCCACTGTAACTTAGCCACTGATGAACCTTAAAGCTGAGTATTTTATTAACACCT
GATTTGTATTCCATTATATTCAAAATGCATCTTTGGTATTGTGCCTCTGCTCCCATCTCTCTCTTTGCCTCATAGATTTAGCTATGTTGG

>27263_27263_6_ERC1-GPC5_ERC1_chr12_1250953_ENST00000589028_GPC5_chr13_93518535_ENST00000377067_length(amino acids)=584AA_BP=
MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT
LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL
HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSK
EAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ERC1-GPC5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ERC1-GPC5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ERC1-GPC5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource