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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ERMP1-RBBP8 (FusionGDB2 ID:27437)

Fusion Gene Summary for ERMP1-RBBP8

check button Fusion gene summary
Fusion gene informationFusion gene name: ERMP1-RBBP8
Fusion gene ID: 27437
HgeneTgene
Gene symbol

ERMP1

RBBP8

Gene ID

79956

5932

Gene nameendoplasmic reticulum metallopeptidase 1RB binding protein 8, endonuclease
SynonymsFXNA|KIAA1815|bA207C16.3COM1|CTIP|JWDS|RIM|SAE2|SCKL2
Cytomap

9p24.1

18q11.2

Type of geneprotein-codingprotein-coding
Descriptionendoplasmic reticulum metallopeptidase 1Felix-inaaminopeptidase FxnabA207C16.3 (novel protein similar to predicted yeast, plant and worm proteins)DNA endonuclease RBBP8CTBP-interacting proteinRBBP-8retinoblastoma binding protein 8sporulation in the absence of SPO11 protein 2 homolog
Modification date2020032020200328
UniProtAcc

Q7Z2K6

RBBP8NL,C20orf151

Ensembl transtripts involved in fusion geneENST00000339450, ENST00000214893, 
ENST00000381506, ENST00000543230, 
ENST00000581687, ENST00000327155, 
ENST00000360790, ENST00000399722, 
ENST00000399725, 
Fusion gene scores* DoF score6 X 5 X 5=15012 X 12 X 6=864
# samples 615
** MAII scorelog2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/864*10)=-2.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ERMP1 [Title/Abstract] AND RBBP8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointERMP1(5830727)-RBBP8(20555116), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ERMP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RBBP8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-6A-AB49-01AERMP1chr9

5830727

-RBBP8chr18

20555116

+


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Fusion Gene ORF analysis for ERMP1-RBBP8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000339450ENST00000581687ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000214893ENST00000327155ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000214893ENST00000360790ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000214893ENST00000399722ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000214893ENST00000399725ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000381506ENST00000327155ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000381506ENST00000360790ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000381506ENST00000399722ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-3CDSENST00000381506ENST00000399725ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-intronENST00000214893ENST00000581687ERMP1chr9

5830727

-RBBP8chr18

20555116

+
5UTR-intronENST00000381506ENST00000581687ERMP1chr9

5830727

-RBBP8chr18

20555116

+
In-frameENST00000339450ENST00000327155ERMP1chr9

5830727

-RBBP8chr18

20555116

+
In-frameENST00000339450ENST00000360790ERMP1chr9

5830727

-RBBP8chr18

20555116

+
In-frameENST00000339450ENST00000399722ERMP1chr9

5830727

-RBBP8chr18

20555116

+
In-frameENST00000339450ENST00000399725ERMP1chr9

5830727

-RBBP8chr18

20555116

+
intron-3CDSENST00000543230ENST00000327155ERMP1chr9

5830727

-RBBP8chr18

20555116

+
intron-3CDSENST00000543230ENST00000360790ERMP1chr9

5830727

-RBBP8chr18

20555116

+
intron-3CDSENST00000543230ENST00000399722ERMP1chr9

5830727

-RBBP8chr18

20555116

+
intron-3CDSENST00000543230ENST00000399725ERMP1chr9

5830727

-RBBP8chr18

20555116

+
intron-intronENST00000543230ENST00000581687ERMP1chr9

5830727

-RBBP8chr18

20555116

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000339450ERMP1chr95830727-ENST00000327155RBBP8chr1820555116+33097305430621002
ENST00000339450ERMP1chr95830727-ENST00000399722RBBP8chr1820555116+33117305430621002
ENST00000339450ERMP1chr95830727-ENST00000399725RBBP8chr1820555116+3212730542972972
ENST00000339450ERMP1chr95830727-ENST00000360790RBBP8chr1820555116+32087305430771007

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000339450ENST00000327155ERMP1chr95830727-RBBP8chr1820555116+0.0002532090.99974674
ENST00000339450ENST00000399722ERMP1chr95830727-RBBP8chr1820555116+0.0002497120.9997503
ENST00000339450ENST00000399725ERMP1chr95830727-RBBP8chr1820555116+0.0003219830.999678
ENST00000339450ENST00000360790ERMP1chr95830727-RBBP8chr1820555116+0.0003315870.9996685

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Fusion Genomic Features for ERMP1-RBBP8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ERMP1chr95830726-RBBP8chr1820555115+4.42E-050.9999558
ERMP1chr95830726-RBBP8chr1820555115+4.42E-050.9999558

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ERMP1-RBBP8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:5830727/chr18:20555116)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ERMP1

Q7Z2K6

RBBP8

RBBP8NL,C20orf151

FUNCTION: Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures. {ECO:0000250|UniProtKB:Q6UPR8}.664

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-2151_63213905.0Topological domainCytoplasmic
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-21564_84213905.0TransmembraneHelical%3B Name%3D1
TgeneRBBP8chr9:5830727chr18:20555116ENST00000327155419490_494120898.0MotifNote=PXDLS motif
TgeneRBBP8chr9:5830727chr18:20555116ENST00000327155419840_842120898.0MotifKLHL15-binding
TgeneRBBP8chr9:5830727chr18:20555116ENST00000399722419490_494120898.0MotifNote=PXDLS motif
TgeneRBBP8chr9:5830727chr18:20555116ENST00000399722419840_842120898.0MotifKLHL15-binding
TgeneRBBP8chr9:5830727chr18:20555116ENST00000399725418490_494120868.0MotifNote=PXDLS motif
TgeneRBBP8chr9:5830727chr18:20555116ENST00000399725418840_842120868.0MotifKLHL15-binding
TgeneRBBP8chr9:5830727chr18:20555116ENST00000327155419509_557120898.0RegionNote=Damage-recruitment motif
TgeneRBBP8chr9:5830727chr18:20555116ENST00000399722419509_557120898.0RegionNote=Damage-recruitment motif
TgeneRBBP8chr9:5830727chr18:20555116ENST00000399725418509_557120868.0RegionNote=Damage-recruitment motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215421_457213905.0Topological domainCytoplasmic
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215479_489213905.0Topological domainLumenal
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215511_519213905.0Topological domainCytoplasmic
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215541_541213905.0Topological domainLumenal
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215563_579213905.0Topological domainCytoplasmic
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215601_621213905.0Topological domainLumenal
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215643_651213905.0Topological domainCytoplasmic
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215673_904213905.0Topological domainLumenal
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-21585_399213905.0Topological domainLumenal
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215400_420213905.0TransmembraneHelical%3B Name%3D2
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215458_478213905.0TransmembraneHelical%3B Name%3D3
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215490_510213905.0TransmembraneHelical%3B Name%3D4
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215520_540213905.0TransmembraneHelical%3B Name%3D5
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215542_562213905.0TransmembraneHelical%3B Name%3D6
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215580_600213905.0TransmembraneHelical%3B Name%3D7
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215622_642213905.0TransmembraneHelical%3B Name%3D8
HgeneERMP1chr9:5830727chr18:20555116ENST00000339450-215652_672213905.0TransmembraneHelical%3B Name%3D9
TgeneRBBP8chr9:5830727chr18:20555116ENST0000032715541928_157120898.0Coiled coilOntology_term=ECO:0000255
TgeneRBBP8chr9:5830727chr18:20555116ENST0000039972241928_157120898.0Coiled coilOntology_term=ECO:0000255
TgeneRBBP8chr9:5830727chr18:20555116ENST0000039972541828_157120868.0Coiled coilOntology_term=ECO:0000255
TgeneRBBP8chr9:5830727chr18:20555116ENST0000032715541922_45120898.0RegionNote=Essential for binding to the MRN complex and for RPA focus formation on DNA damage
TgeneRBBP8chr9:5830727chr18:20555116ENST0000039972241922_45120898.0RegionNote=Essential for binding to the MRN complex and for RPA focus formation on DNA damage
TgeneRBBP8chr9:5830727chr18:20555116ENST0000039972541822_45120868.0RegionNote=Essential for binding to the MRN complex and for RPA focus formation on DNA damage


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Fusion Gene Sequence for ERMP1-RBBP8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27437_27437_1_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000327155_length(transcript)=3309nt_BP=730nt
AGGAGGCGCTGCGGCAGCGACGGCGGCGTCGGCGGCGGCCGGGGCTGTCGCGGGTTGGGGCGGTTGGGCTGGCAGCTGAGGCTCGTGGCC
ATGGAGTGGGGTTCTGAGTCGGCTGCTGTGAGGCGGCACCGCGTCGGAGTAGAGCGTCGAGAGGGAGCGGCGGCCGCGCCACCGCCGGAG
AGGGAGGCCCGAGCGCAGGAGCCTCTGGTGGATGGGTGCAGCGGCGGCGGGAGGACGCGGAAGAGGAGCCCCGGGGGTAGCGGCGGCGCG
AGCAGGGGCGCGGGGACCGGGCTGTCTGAGGTGCGCGCCGCGCTGGGGCTCGCGCTCTACCTGATCGCGCTGCGGACGCTGGTGCAGCTC
TCGCTGCAGCAGCTCGTGCTACGCGGGGCCGCTGGACACCGCGGGGAGTTCGACGCGCTCCAAGCCAGGGATTATCTTGAACACATAACC
TCCATTGGCCCCAGGACTACAGGAAGTCCAGAAAATGAAATTCTGACCGTGCACTACCTTTTGGAACAGATTAAACTGATTGAAGTGCAA
AGCAACAGCCTTCATAAGATTTCAGTAGATGTACAACGGCCCACAGGCTCTTTTAGCATTGATTTCTTGGGAGGTTTTACAAGCTATTAT
GACAACATCACCAATGTTGTGGTAAAGCTGGAACCCAGAGATGGAGCCCAGCATGCTGTCTTGGCTAATTGTCATTTTGACTCAGTAGCA
AACTCACCAGTGAATGAAAGGAATACTCTACAGGAAGAAAATAAAAAGCTTTCTGAACAACTCCAGCAGAAAATTGAGAATGATCAACAG
CATCAAGCAGCTGAGCTTGAATGTGAGGAAGACGTTATTCCAGATTCACCGATAACAGCCTTCTCATTTTCTGGCGTTAACCGGCTACGA
AGAAAGGAGAACCCCCATGTCCGATACATAGAACAAACACATACTAAATTGGAGCACTCTGTGTGTGCAAATGAAATGAGAAAAGTTTCC
AAGTCTTCAACTCATCCACAACATAATCCTAATGAAAATGAAATTCTAGTAGCTGACACTTATGACCAAAGTCAATCTCCAATGGCCAAA
GCACATGGAACAAGCAGCTATACCCCTGATAAGTCATCTTTTAATTTAGCTACAGTTGTTGCTGAAACACTTGGACTTGGTGTTCAAGAA
GAATCTGAAACTCAAGGTCCCATGAGCCCCCTTGGTGATGAGCTCTACCACTGTCTGGAAGGAAATCACAAGAAACAGCCTTTTGAGGAA
TCTACAAGAAATACTGAAGATAGTTTAAGATTTTCAGATTCTACTTCAAAGACTCCTCCTCAAGAAGAATTACCTACTCGAGTGTCATCT
CCTGTATTTGGAGCTACCTCTAGTATCAAAAGTGGTTTAGATTTGAATACAAGTTTGTCCCCTTCTCTTTTACAGCCTGGGAAAAAAAAA
CATCTGAAAACACTCCCTTTTAGCAACACTTGTATATCTAGATTAGAAAAAACTAGATCAAAATCTGAAGATAGTGCCCTTTTCACACAT
CACAGTCTTGGGTCTGAAGTGAACAAGATCATTATCCAGTCATCTAATAAACAGATACTTATAAATAAAAATATAAGTGAATCCCTAGGT
GAACAGAATAGGACTGAGTACGGTAAAGATTCTAACACTGATAAACATTTGGAGCCCCTGAAATCATTGGGAGGCCGAACATCCAAAAGG
AAGAAAACTGAGGAAGAAAGTGAACATGAAGTAAGCTGCCCCCAAGCTTCTTTTGATAAAGAAAATGCTTTCCCTTTTCCAATGGATAAT
CAGTTTTCCATGAATGGAGACTGTGTGATGGATAAACCTCTGGATCTGTCTGATCGATTTTCAGCTATTCAGCGTCAAGAGAAAAGCCAA
GGAAGTGAGACTTCTAAAAACAAATTTAGGCAAGTGACTCTTTATGAGGCTTTGAAGACCATTCCAAAGGGCTTTTCCTCAAGCCGTAAG
GCCTCAGATGGCAACTGCACGTTGCCCAAAGATTCCCCAGGGGAGCCCTGTTCACAGGAATGCATCATCCTTCAGCCCTTGAATAAATGC
TCTCCAGACAATAAACCATCATTACAAATAAAAGAAGAAAATGCTGTCTTTAAAATTCCTCTACGTCCACGTGAAAGTTTGGAGACTGAG
AATGTTTTAGATGACATAAAGAGTGCTGGTTCTCATGAGCCAATAAAAATACAAACCAGGTCAGACCATGGAGGATGTGAACTTGCATCA
GTTCTTCAGTTAAATCCATGTAGAACTGGTAAAATAAAGTCTCTACAAAACAACCAAGATGTATCCTTTGAAAATATCCAGTGGAGTATA
GATCCGGGAGCAGACCTTTCTCAGTATAAAATGGATGTTACTGTAATAGATACAAAGGATGGCAGTCAGTCAAAATTAGGAGGAGAGACA
GTGGACATGGACTGTACATTGGTTAGTGAAACCGTTCTCTTAAAAATGAAGAAGCAAGAGCAGAAGGGAGAAAAAAGTTCAAATGAAGAA
AGAAAAATGAATGATAGCTTGGAAGATATGTTTGATCGGACAACACATGAAGAGTATGAATCCTGTTTGGCAGACAGTTTCTCCCAAGCA
GCAGATGAAGAGGAGGAATTGTCTACTGCCACAAAGAAACTACACACTCATGGTGATAAACAAGACAAAGTCAAGCAGAAAGCGTTTGTG
GAGCCGTATTTTAAAGGTGATGAAAGAGAGACTAGCTTGCAAAATTTTCCTCATATTGAGGTGGTTCGGAAAAAAGAGGAGAGAAGAAAA
CTGCTTGGGCACACGTGTAAGGAATGTGAAATTTATTATGCAGATATGCCAGCAGAAGAAAGAGAAAAGAAATTGGCTTCCTGCTCAAGA
CACCGATTCCGCTACATTCCACCCAACACACCAGAGAATTTTTGGGAAGTTGGTTTTCCTTCCACTCAGACTTGTATGGAAAGAGGTTAT
ATTAAGGAAGATCTTGATCCTTGTCCTCGTCCAAAAAGACGTCAGCCTTACAACGCAATATTTTCTCCAAAAGGCAAGGAGCAGAAGACA
TAGACGTTGAAACAGAAACAGAAGGATGAAGGACAGTTTTTTCCTTCTTAGTTATTTATAGTTAAAGTTGGTACTAAACATTGATTTTTT
TGATCTTCTGTAAATGGATTTATAAATCAGTTTTCTATTGAAAATGTTTGTGATATTTTGCTTTTGCACCTTTAAAACAATAAGGCGCTT

>27437_27437_1_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000327155_length(amino acids)=1002AA_BP=225
MGRLGWQLRLVAMEWGSESAAVRRHRVGVERREGAAAAPPPEREARAQEPLVDGCSGGGRTRKRSPGGSGGASRGAGTGLSEVRAALGLA
LYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISVDVQRPTGSF
SIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPVNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPI
TAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLAT
VVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTS
LSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLE
PLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEAL
KTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQ
TRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKK
QEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERETSLQNFPH
IEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYN

--------------------------------------------------------------
>27437_27437_2_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000360790_length(transcript)=3208nt_BP=730nt
AGGAGGCGCTGCGGCAGCGACGGCGGCGTCGGCGGCGGCCGGGGCTGTCGCGGGTTGGGGCGGTTGGGCTGGCAGCTGAGGCTCGTGGCC
ATGGAGTGGGGTTCTGAGTCGGCTGCTGTGAGGCGGCACCGCGTCGGAGTAGAGCGTCGAGAGGGAGCGGCGGCCGCGCCACCGCCGGAG
AGGGAGGCCCGAGCGCAGGAGCCTCTGGTGGATGGGTGCAGCGGCGGCGGGAGGACGCGGAAGAGGAGCCCCGGGGGTAGCGGCGGCGCG
AGCAGGGGCGCGGGGACCGGGCTGTCTGAGGTGCGCGCCGCGCTGGGGCTCGCGCTCTACCTGATCGCGCTGCGGACGCTGGTGCAGCTC
TCGCTGCAGCAGCTCGTGCTACGCGGGGCCGCTGGACACCGCGGGGAGTTCGACGCGCTCCAAGCCAGGGATTATCTTGAACACATAACC
TCCATTGGCCCCAGGACTACAGGAAGTCCAGAAAATGAAATTCTGACCGTGCACTACCTTTTGGAACAGATTAAACTGATTGAAGTGCAA
AGCAACAGCCTTCATAAGATTTCAGTAGATGTACAACGGCCCACAGGCTCTTTTAGCATTGATTTCTTGGGAGGTTTTACAAGCTATTAT
GACAACATCACCAATGTTGTGGTAAAGCTGGAACCCAGAGATGGAGCCCAGCATGCTGTCTTGGCTAATTGTCATTTTGACTCAGTAGCA
AACTCACCAGTGAATGAAAGGAATACTCTACAGGAAGAAAATAAAAAGCTTTCTGAACAACTCCAGCAGAAAATTGAGAATGATCAACAG
CATCAAGCAGCTGAGCTTGAATGTGAGGAAGACGTTATTCCAGATTCACCGATAACAGCCTTCTCATTTTCTGGCGTTAACCGGCTACGA
AGAAAGGAGAACCCCCATGTCCGATACATAGAACAAACACATACTAAATTGGAGCACTCTGTGTGTGCAAATGAAATGAGAAAAGTTTCC
AAGTCTTCAACTCATCCACAACATAATCCTAATGAAAATGAAATTCTAGTAGCTGACACTTATGACCAAAGTCAATCTCCAATGGCCAAA
GCACATGGAACAAGCAGCTATACCCCTGATAAGTCATCTTTTAATTTAGCTACAGTTGTTGCTGAAACACTTGGACTTGGTGTTCAAGAA
GAATCTGAAACTCAAGGTCCCATGAGCCCCCTTGGTGATGAGCTCTACCACTGTCTGGAAGGAAATCACAAGAAACAGCCTTTTGAGGAA
TCTACAAGAAATACTGAAGATAGTTTAAGATTTTCAGATTCTACTTCAAAGACTCCTCCTCAAGAAGAATTACCTACTCGAGTGTCATCT
CCTGTATTTGGAGCTACCTCTAGTATCAAAAGTGGTTTAGATTTGAATACAAGTTTGTCCCCTTCTCTTTTACAGCCTGGGAAAAAAAAA
CATCTGAAAACACTCCCTTTTAGCAACACTTGTATATCTAGATTAGAAAAAACTAGATCAAAATCTGAAGATAGTGCCCTTTTCACACAT
CACAGTCTTGGGTCTGAAGTGAACAAGATCATTATCCAGTCATCTAATAAACAGATACTTATAAATAAAAATATAAGTGAATCCCTAGGT
GAACAGAATAGGACTGAGTACGGTAAAGATTCTAACACTGATAAACATTTGGAGCCCCTGAAATCATTGGGAGGCCGAACATCCAAAAGG
AAGAAAACTGAGGAAGAAAGTGAACATGAAGTAAGCTGCCCCCAAGCTTCTTTTGATAAAGAAAATGCTTTCCCTTTTCCAATGGATAAT
CAGTTTTCCATGAATGGAGACTGTGTGATGGATAAACCTCTGGATCTGTCTGATCGATTTTCAGCTATTCAGCGTCAAGAGAAAAGCCAA
GGAAGTGAGACTTCTAAAAACAAATTTAGGCAAGTGACTCTTTATGAGGCTTTGAAGACCATTCCAAAGGGCTTTTCCTCAAGCCGTAAG
GCCTCAGATGGCAACTGCACGTTGCCCAAAGATTCCCCAGGGGAGCCCTGTTCACAGGAATGCATCATCCTTCAGCCCTTGAATAAATGC
TCTCCAGACAATAAACCATCATTACAAATAAAAGAAGAAAATGCTGTCTTTAAAATTCCTCTACGTCCACGTGAAAGTTTGGAGACTGAG
AATGTTTTAGATGACATAAAGAGTGCTGGTTCTCATGAGCCAATAAAAATACAAACCAGGTCAGACCATGGAGGATGTGAACTTGCATCA
GTTCTTCAGTTAAATCCATGTAGAACTGGTAAAATAAAGTCTCTACAAAACAACCAAGATGTATCCTTTGAAAATATCCAGTGGAGTATA
GATCCGGGAGCAGACCTTTCTCAGTATAAAATGGATGTTACTGTAATAGATACAAAGGATGGCAGTCAGTCAAAATTAGGAGGAGAGACA
GTGGACATGGACTGTACATTGGTTAGTGAAACCGTTCTCTTAAAAATGAAGAAGCAAGAGCAGAAGGGAGAAAAAAGTTCAATGCTCTTT
TACATAGATGAAGAAAGAAAAATGAATGATAGCTTGGAAGATATGTTTGATCGGACAACACATGAAGAGTATGAATCCTGTTTGGCAGAC
AGTTTCTCCCAAGCAGCAGATGAAGAGGAGGAATTGTCTACTGCCACAAAGAAACTACACACTCATGGTGATAAACAAGACAAAGTCAAG
CAGAAAGCGTTTGTGGAGCCGTATTTTAAAGGTGATGAAAGAGAGACTAGCTTGCAAAATTTTCCTCATATTGAGGTGGTTCGGAAAAAA
GAGGAGAGAAGAAAACTGCTTGGGCACACGTGTAAGGAATGTGAAATTTATTATGCAGATATGCCAGCAGAAGAAAGAGAAAAGAAATTG
GCTTCCTGCTCAAGACACCGATTCCGCTACATTCCACCCAACACACCAGAGAATTTTTGGGAAGTTGGTTTTCCTTCCACTCAGACTTGT
ATGGAAAGAGGTTATATTAAGGAAGATCTTGATCCTTGTCCTCGTCCAAAAAGACGTCAGCCTTACAACGCAATATTTTCTCCAAAAGGC
AAGGAGCAGAAGACATAGACGTTGAAACAGAAACAGAAGGATGAAGGACAGTTTTTTCCTTCTTAGTTATTTATAGTTAAAGTTGGTACT

>27437_27437_2_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000360790_length(amino acids)=1007AA_BP=225
MGRLGWQLRLVAMEWGSESAAVRRHRVGVERREGAAAAPPPEREARAQEPLVDGCSGGGRTRKRSPGGSGGASRGAGTGLSEVRAALGLA
LYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISVDVQRPTGSF
SIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPVNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPI
TAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLAT
VVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTS
LSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLE
PLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEAL
KTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQ
TRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKK
QEQKGEKSSMLFYIDEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERETSL
QNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKR

--------------------------------------------------------------
>27437_27437_3_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000399722_length(transcript)=3311nt_BP=730nt
AGGAGGCGCTGCGGCAGCGACGGCGGCGTCGGCGGCGGCCGGGGCTGTCGCGGGTTGGGGCGGTTGGGCTGGCAGCTGAGGCTCGTGGCC
ATGGAGTGGGGTTCTGAGTCGGCTGCTGTGAGGCGGCACCGCGTCGGAGTAGAGCGTCGAGAGGGAGCGGCGGCCGCGCCACCGCCGGAG
AGGGAGGCCCGAGCGCAGGAGCCTCTGGTGGATGGGTGCAGCGGCGGCGGGAGGACGCGGAAGAGGAGCCCCGGGGGTAGCGGCGGCGCG
AGCAGGGGCGCGGGGACCGGGCTGTCTGAGGTGCGCGCCGCGCTGGGGCTCGCGCTCTACCTGATCGCGCTGCGGACGCTGGTGCAGCTC
TCGCTGCAGCAGCTCGTGCTACGCGGGGCCGCTGGACACCGCGGGGAGTTCGACGCGCTCCAAGCCAGGGATTATCTTGAACACATAACC
TCCATTGGCCCCAGGACTACAGGAAGTCCAGAAAATGAAATTCTGACCGTGCACTACCTTTTGGAACAGATTAAACTGATTGAAGTGCAA
AGCAACAGCCTTCATAAGATTTCAGTAGATGTACAACGGCCCACAGGCTCTTTTAGCATTGATTTCTTGGGAGGTTTTACAAGCTATTAT
GACAACATCACCAATGTTGTGGTAAAGCTGGAACCCAGAGATGGAGCCCAGCATGCTGTCTTGGCTAATTGTCATTTTGACTCAGTAGCA
AACTCACCAGTGAATGAAAGGAATACTCTACAGGAAGAAAATAAAAAGCTTTCTGAACAACTCCAGCAGAAAATTGAGAATGATCAACAG
CATCAAGCAGCTGAGCTTGAATGTGAGGAAGACGTTATTCCAGATTCACCGATAACAGCCTTCTCATTTTCTGGCGTTAACCGGCTACGA
AGAAAGGAGAACCCCCATGTCCGATACATAGAACAAACACATACTAAATTGGAGCACTCTGTGTGTGCAAATGAAATGAGAAAAGTTTCC
AAGTCTTCAACTCATCCACAACATAATCCTAATGAAAATGAAATTCTAGTAGCTGACACTTATGACCAAAGTCAATCTCCAATGGCCAAA
GCACATGGAACAAGCAGCTATACCCCTGATAAGTCATCTTTTAATTTAGCTACAGTTGTTGCTGAAACACTTGGACTTGGTGTTCAAGAA
GAATCTGAAACTCAAGGTCCCATGAGCCCCCTTGGTGATGAGCTCTACCACTGTCTGGAAGGAAATCACAAGAAACAGCCTTTTGAGGAA
TCTACAAGAAATACTGAAGATAGTTTAAGATTTTCAGATTCTACTTCAAAGACTCCTCCTCAAGAAGAATTACCTACTCGAGTGTCATCT
CCTGTATTTGGAGCTACCTCTAGTATCAAAAGTGGTTTAGATTTGAATACAAGTTTGTCCCCTTCTCTTTTACAGCCTGGGAAAAAAAAA
CATCTGAAAACACTCCCTTTTAGCAACACTTGTATATCTAGATTAGAAAAAACTAGATCAAAATCTGAAGATAGTGCCCTTTTCACACAT
CACAGTCTTGGGTCTGAAGTGAACAAGATCATTATCCAGTCATCTAATAAACAGATACTTATAAATAAAAATATAAGTGAATCCCTAGGT
GAACAGAATAGGACTGAGTACGGTAAAGATTCTAACACTGATAAACATTTGGAGCCCCTGAAATCATTGGGAGGCCGAACATCCAAAAGG
AAGAAAACTGAGGAAGAAAGTGAACATGAAGTAAGCTGCCCCCAAGCTTCTTTTGATAAAGAAAATGCTTTCCCTTTTCCAATGGATAAT
CAGTTTTCCATGAATGGAGACTGTGTGATGGATAAACCTCTGGATCTGTCTGATCGATTTTCAGCTATTCAGCGTCAAGAGAAAAGCCAA
GGAAGTGAGACTTCTAAAAACAAATTTAGGCAAGTGACTCTTTATGAGGCTTTGAAGACCATTCCAAAGGGCTTTTCCTCAAGCCGTAAG
GCCTCAGATGGCAACTGCACGTTGCCCAAAGATTCCCCAGGGGAGCCCTGTTCACAGGAATGCATCATCCTTCAGCCCTTGAATAAATGC
TCTCCAGACAATAAACCATCATTACAAATAAAAGAAGAAAATGCTGTCTTTAAAATTCCTCTACGTCCACGTGAAAGTTTGGAGACTGAG
AATGTTTTAGATGACATAAAGAGTGCTGGTTCTCATGAGCCAATAAAAATACAAACCAGGTCAGACCATGGAGGATGTGAACTTGCATCA
GTTCTTCAGTTAAATCCATGTAGAACTGGTAAAATAAAGTCTCTACAAAACAACCAAGATGTATCCTTTGAAAATATCCAGTGGAGTATA
GATCCGGGAGCAGACCTTTCTCAGTATAAAATGGATGTTACTGTAATAGATACAAAGGATGGCAGTCAGTCAAAATTAGGAGGAGAGACA
GTGGACATGGACTGTACATTGGTTAGTGAAACCGTTCTCTTAAAAATGAAGAAGCAAGAGCAGAAGGGAGAAAAAAGTTCAAATGAAGAA
AGAAAAATGAATGATAGCTTGGAAGATATGTTTGATCGGACAACACATGAAGAGTATGAATCCTGTTTGGCAGACAGTTTCTCCCAAGCA
GCAGATGAAGAGGAGGAATTGTCTACTGCCACAAAGAAACTACACACTCATGGTGATAAACAAGACAAAGTCAAGCAGAAAGCGTTTGTG
GAGCCGTATTTTAAAGGTGATGAAAGAGAGACTAGCTTGCAAAATTTTCCTCATATTGAGGTGGTTCGGAAAAAAGAGGAGAGAAGAAAA
CTGCTTGGGCACACGTGTAAGGAATGTGAAATTTATTATGCAGATATGCCAGCAGAAGAAAGAGAAAAGAAATTGGCTTCCTGCTCAAGA
CACCGATTCCGCTACATTCCACCCAACACACCAGAGAATTTTTGGGAAGTTGGTTTTCCTTCCACTCAGACTTGTATGGAAAGAGGTTAT
ATTAAGGAAGATCTTGATCCTTGTCCTCGTCCAAAAAGACGTCAGCCTTACAACGCAATATTTTCTCCAAAAGGCAAGGAGCAGAAGACA
TAGACGTTGAAACAGAAACAGAAGGATGAAGGACAGTTTTTTCCTTCTTAGTTATTTATAGTTAAAGTTGGTACTAAACATTGATTTTTT
TGATCTTCTGTAAATGGATTTATAAATCAGTTTTCTATTGAAAATGTTTGTGATATTTTGCTTTTGCACCTTTAAAACAATAAGGCGCTT

>27437_27437_3_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000399722_length(amino acids)=1002AA_BP=225
MGRLGWQLRLVAMEWGSESAAVRRHRVGVERREGAAAAPPPEREARAQEPLVDGCSGGGRTRKRSPGGSGGASRGAGTGLSEVRAALGLA
LYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISVDVQRPTGSF
SIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPVNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPI
TAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLAT
VVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTS
LSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLE
PLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEAL
KTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQ
TRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKK
QEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERETSLQNFPH
IEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYN

--------------------------------------------------------------
>27437_27437_4_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000399725_length(transcript)=3212nt_BP=730nt
AGGAGGCGCTGCGGCAGCGACGGCGGCGTCGGCGGCGGCCGGGGCTGTCGCGGGTTGGGGCGGTTGGGCTGGCAGCTGAGGCTCGTGGCC
ATGGAGTGGGGTTCTGAGTCGGCTGCTGTGAGGCGGCACCGCGTCGGAGTAGAGCGTCGAGAGGGAGCGGCGGCCGCGCCACCGCCGGAG
AGGGAGGCCCGAGCGCAGGAGCCTCTGGTGGATGGGTGCAGCGGCGGCGGGAGGACGCGGAAGAGGAGCCCCGGGGGTAGCGGCGGCGCG
AGCAGGGGCGCGGGGACCGGGCTGTCTGAGGTGCGCGCCGCGCTGGGGCTCGCGCTCTACCTGATCGCGCTGCGGACGCTGGTGCAGCTC
TCGCTGCAGCAGCTCGTGCTACGCGGGGCCGCTGGACACCGCGGGGAGTTCGACGCGCTCCAAGCCAGGGATTATCTTGAACACATAACC
TCCATTGGCCCCAGGACTACAGGAAGTCCAGAAAATGAAATTCTGACCGTGCACTACCTTTTGGAACAGATTAAACTGATTGAAGTGCAA
AGCAACAGCCTTCATAAGATTTCAGTAGATGTACAACGGCCCACAGGCTCTTTTAGCATTGATTTCTTGGGAGGTTTTACAAGCTATTAT
GACAACATCACCAATGTTGTGGTAAAGCTGGAACCCAGAGATGGAGCCCAGCATGCTGTCTTGGCTAATTGTCATTTTGACTCAGTAGCA
AACTCACCAGTGAATGAAAGGAATACTCTACAGGAAGAAAATAAAAAGCTTTCTGAACAACTCCAGCAGAAAATTGAGAATGATCAACAG
CATCAAGCAGCTGAGCTTGAATGTGAGGAAGACGTTATTCCAGATTCACCGATAACAGCCTTCTCATTTTCTGGCGTTAACCGGCTACGA
AGAAAGGAGAACCCCCATGTCCGATACATAGAACAAACACATACTAAATTGGAGCACTCTGTGTGTGCAAATGAAATGAGAAAAGTTTCC
AAGTCTTCAACTCATCCACAACATAATCCTAATGAAAATGAAATTCTAGTAGCTGACACTTATGACCAAAGTCAATCTCCAATGGCCAAA
GCACATGGAACAAGCAGCTATACCCCTGATAAGTCATCTTTTAATTTAGCTACAGTTGTTGCTGAAACACTTGGACTTGGTGTTCAAGAA
GAATCTGAAACTCAAGGTCCCATGAGCCCCCTTGGTGATGAGCTCTACCACTGTCTGGAAGGAAATCACAAGAAACAGCCTTTTGAGGAA
TCTACAAGAAATACTGAAGATAGTTTAAGATTTTCAGATTCTACTTCAAAGACTCCTCCTCAAGAAGAATTACCTACTCGAGTGTCATCT
CCTGTATTTGGAGCTACCTCTAGTATCAAAAGTGGTTTAGATTTGAATACAAGTTTGTCCCCTTCTCTTTTACAGCCTGGGAAAAAAAAA
CATCTGAAAACACTCCCTTTTAGCAACACTTGTATATCTAGATTAGAAAAAACTAGATCAAAATCTGAAGATAGTGCCCTTTTCACACAT
CACAGTCTTGGGTCTGAAGTGAACAAGATCATTATCCAGTCATCTAATAAACAGATACTTATAAATAAAAATATAAGTGAATCCCTAGGT
GAACAGAATAGGACTGAGTACGGTAAAGATTCTAACACTGATAAACATTTGGAGCCCCTGAAATCATTGGGAGGCCGAACATCCAAAAGG
AAGAAAACTGAGGAAGAAAGTGAACATGAAGTAAGCTGCCCCCAAGCTTCTTTTGATAAAGAAAATGCTTTCCCTTTTCCAATGGATAAT
CAGTTTTCCATGAATGGAGACTGTGTGATGGATAAACCTCTGGATCTGTCTGATCGATTTTCAGCTATTCAGCGTCAAGAGAAAAGCCAA
GGAAGTGAGACTTCTAAAAACAAATTTAGGCAAGTGACTCTTTATGAGGCTTTGAAGACCATTCCAAAGGGCTTTTCCTCAAGCCGTAAG
GCCTCAGATGGCAACTGCACGTTGCCCAAAGATTCCCCAGGGGAGCCCTGTTCACAGGAATGCATCATCCTTCAGCCCTTGAATAAATGC
TCTCCAGACAATAAACCATCATTACAAATAAAAGAAGAAAATGCTGTCTTTAAAATTCCTCTACGTCCACGTGAAAGTTTGGAGACTGAG
AATGTTTTAGATGACATAAAGAGTGCTGGTTCTCATGAGCCAATAAAAATACAAACCAGGTCAGACCATGGAGGATGTGAACTTGCATCA
GTTCTTCAGTTAAATCCATGTAGAACTGGTAAAATAAAGTCTCTACAAAACAACCAAGATGTATCCTTTGAAAATATCCAGTGGAGTATA
GATCCGGGAGCAGACCTTTCTCAGTATAAAATGGATGTTACTGTAATAGATACAAAGGATGGCAGTCAGTCAAAATTAGGAGGAGAGACA
GTGGACATGGACTGTACATTGGTTAGTGAAACCGTTCTCTTAAAAATGAAGAAGCAAGAGCAGAAGGGAGAAAAAAGTTCAAATGAAGAA
AGAAAAATGAATGATAGCTTGGAAGATATGTTTGATCGGACAACACATGAAGAGTATGAATCCTGTTTGGCAGACAGTTTCTCCCAAGCA
GCAGATGAAGAGGAGGAATTGTCTACTGCCACAAAGAAACTACACACTCATGGTGATAAACAAGACAAAGTCAAGCAGAAAGCGTTTGTG
GAGCCGTATTTTAAAGGTGATGAAAGTATTATGCAGATATGCCAGCAGAAGAAAGAGAAAAGAAATTGGCTTCCTGCTCAAGACACCGAT
TCCGCTACATTCCACCCAACACACCAGAGAATTTTTGGGAAGTTGGTTTTCCTTCCACTCAGACTTGTATGGAAAGAGGTTATATTAAGG
AAGATCTTGATCCTTGTCCTCGTCCAAAAAGACGTCAGCCTTACAACGCAATATTTTCTCCAAAAGGCAAGGAGCAGAAGACATAGACGT
TGAAACAGAAACAGAAGGATGAAGGACAGTTTTTTCCTTCTTAGTTATTTATAGTTAAAGTTGGTACTAAACATTGATTTTTTTGATCTT
CTGTAAATGGATTTATAAATCAGTTTTCTATTGAAAATGTTTGTGATATTTTGCTTTTGCACCTTTAAAACAATAAGGCGCTTTCATTTT

>27437_27437_4_ERMP1-RBBP8_ERMP1_chr9_5830727_ENST00000339450_RBBP8_chr18_20555116_ENST00000399725_length(amino acids)=972AA_BP=225
MGRLGWQLRLVAMEWGSESAAVRRHRVGVERREGAAAAPPPEREARAQEPLVDGCSGGGRTRKRSPGGSGGASRGAGTGLSEVRAALGLA
LYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISVDVQRPTGSF
SIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPVNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPI
TAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLAT
VVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTS
LSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLE
PLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEAL
KTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQ
TRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKK
QEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDESIMQICQQKK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ERMP1-RBBP8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ERMP1-RBBP8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ERMP1-RBBP8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource