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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AFTPH-ELF1 (FusionGDB2 ID:2747)

Fusion Gene Summary for AFTPH-ELF1

check button Fusion gene summary
Fusion gene informationFusion gene name: AFTPH-ELF1
Fusion gene ID: 2747
HgeneTgene
Gene symbol

AFTPH

ELF1

Gene ID

54812

84337

Gene nameaftiphilinelongation factor 1 homolog
SynonymsNbla10388ELF1
Cytomap

2p14

19p13.2

Type of geneprotein-codingprotein-coding
Descriptionaftiphilinaftiphilin proteintranscription elongation factor 1 homologELF1 homolog, elongation factor 1elongation factor 1 homolog (ELF1, S. cerevisiae)
Modification date2020031320200313
UniProtAcc

Q6ULP2

P32519

Ensembl transtripts involved in fusion geneENST00000238855, ENST00000238856, 
ENST00000409183, ENST00000409933, 
ENST00000422803, ENST00000487769, 
ENST00000239882, ENST00000498824, 
ENST00000442101, 
Fusion gene scores* DoF score7 X 6 X 5=21013 X 11 X 5=715
# samples 813
** MAII scorelog2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/715*10)=-2.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AFTPH [Title/Abstract] AND ELF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAFTPH(64796813)-ELF1(41556418), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across AFTPH (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ELF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4READTCGA-G5-6235-01AAFTPHchr2

64796813

-ELF1chr13

41556418

-
ChimerDB4READTCGA-G5-6235-01AAFTPHchr2

64796813

+ELF1chr13

41556418

-
ChimerDB4READTCGA-G5-6235AFTPHchr2

64796813

+ELF1chr13

41556418

-


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Fusion Gene ORF analysis for AFTPH-ELF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000238855ENST00000239882AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-5UTRENST00000238856ENST00000239882AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-5UTRENST00000409183ENST00000239882AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-5UTRENST00000409933ENST00000239882AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-5UTRENST00000422803ENST00000239882AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-intronENST00000238855ENST00000498824AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-intronENST00000238856ENST00000498824AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-intronENST00000409183ENST00000498824AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-intronENST00000409933ENST00000498824AFTPHchr2

64796813

+ELF1chr13

41556418

-
5CDS-intronENST00000422803ENST00000498824AFTPHchr2

64796813

+ELF1chr13

41556418

-
In-frameENST00000238855ENST00000442101AFTPHchr2

64796813

+ELF1chr13

41556418

-
In-frameENST00000238856ENST00000442101AFTPHchr2

64796813

+ELF1chr13

41556418

-
In-frameENST00000409183ENST00000442101AFTPHchr2

64796813

+ELF1chr13

41556418

-
In-frameENST00000409933ENST00000442101AFTPHchr2

64796813

+ELF1chr13

41556418

-
In-frameENST00000422803ENST00000442101AFTPHchr2

64796813

+ELF1chr13

41556418

-
intron-3CDSENST00000487769ENST00000442101AFTPHchr2

64796813

+ELF1chr13

41556418

-
intron-5UTRENST00000487769ENST00000239882AFTPHchr2

64796813

+ELF1chr13

41556418

-
intron-intronENST00000487769ENST00000498824AFTPHchr2

64796813

+ELF1chr13

41556418

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000238855AFTPHchr264796813+ENST00000442101ELF1chr1341556418-610625853142638774
ENST00000422803AFTPHchr264796813+ENST00000442101ELF1chr1341556418-610625853142638774
ENST00000238856AFTPHchr264796813+ENST00000442101ELF1chr1341556418-610625853142638774
ENST00000409933AFTPHchr264796813+ENST00000442101ELF1chr1341556418-5792227102324774
ENST00000409183AFTPHchr264796813+ENST00000442101ELF1chr1341556418-4755123414623249595

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000238855ENST00000442101AFTPHchr264796813+ELF1chr1341556418-0.0002716270.9997284
ENST00000422803ENST00000442101AFTPHchr264796813+ELF1chr1341556418-0.0002716270.9997284
ENST00000238856ENST00000442101AFTPHchr264796813+ELF1chr1341556418-0.0002716270.9997284
ENST00000409933ENST00000442101AFTPHchr264796813+ELF1chr1341556418-0.0002749860.99972504
ENST00000409183ENST00000442101AFTPHchr264796813+ELF1chr1341556418-0.0001507840.9998492

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Fusion Genomic Features for AFTPH-ELF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AFTPH-ELF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:64796813/chr13:41556418)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AFTPH

Q6ULP2

ELF1

P32519

FUNCTION: Component of clathrin-coated vesicles (PubMed:15758025). Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (PubMed:15758025). {ECO:0000269|PubMed:15758025}.FUNCTION: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. {ECO:0000269|PubMed:8756667}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238855+51028_31757937.0MotifNote=WXXF motif 1
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238855+510432_435757937.0MotifNote=WXXF motif 2
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238855+510436_438757937.0MotifNote=WXXF motif 3 (partial)
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238855+510478_481757937.0MotifNote=WXXF motif 4
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238856+5928_31757910.0MotifNote=WXXF motif 1
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238856+59432_435757910.0MotifNote=WXXF motif 2
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238856+59436_438757910.0MotifNote=WXXF motif 3 (partial)
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238856+59478_481757910.0MotifNote=WXXF motif 4
HgeneAFTPHchr2:64796813chr13:41556418ENST00000409933+4928_31757937.0MotifNote=WXXF motif 1
HgeneAFTPHchr2:64796813chr13:41556418ENST00000409933+49432_435757937.0MotifNote=WXXF motif 2
HgeneAFTPHchr2:64796813chr13:41556418ENST00000409933+49436_438757937.0MotifNote=WXXF motif 3 (partial)
HgeneAFTPHchr2:64796813chr13:41556418ENST00000409933+49478_481757937.0MotifNote=WXXF motif 4
HgeneAFTPHchr2:64796813chr13:41556418ENST00000422803+51028_31757938.0MotifNote=WXXF motif 1
HgeneAFTPHchr2:64796813chr13:41556418ENST00000422803+510432_435757938.0MotifNote=WXXF motif 2
HgeneAFTPHchr2:64796813chr13:41556418ENST00000422803+510436_438757938.0MotifNote=WXXF motif 3 (partial)
HgeneAFTPHchr2:64796813chr13:41556418ENST00000422803+510478_481757938.0MotifNote=WXXF motif 4
TgeneELF1chr2:64796813chr13:41556418ENST000002398820975_800620.0Compositional biasNote=Poly-Asp
TgeneELF1chr2:64796813chr13:41556418ENST00000442101-1875_8024596.0Compositional biasNote=Poly-Asp
TgeneELF1chr2:64796813chr13:41556418ENST0000023988209208_2900620.0DNA bindingETS
TgeneELF1chr2:64796813chr13:41556418ENST00000442101-18208_29024596.0DNA bindingETS

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238855+510825_829757937.0RegionClathrin-binding
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238856+59825_829757910.0RegionClathrin-binding
HgeneAFTPHchr2:64796813chr13:41556418ENST00000409933+49825_829757937.0RegionClathrin-binding
HgeneAFTPHchr2:64796813chr13:41556418ENST00000422803+510825_829757938.0RegionClathrin-binding


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Fusion Gene Sequence for AFTPH-ELF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2747_2747_1_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000238855_ELF1_chr13_41556418_ENST00000442101_length(transcript)=6106nt_BP=2585nt
GCATGATGGGAGAGTGTGTGGAGTGGGCGGGGGGTCTCCGCGGAGGAGGTGGAGGAGGCGGCGGCGGCGGCGGAAGAGGGCGGAGGGTAG
TGGGATGGGGGTCCCGCGGCAGCGGTGAAACTCCGGGTGGGCGTCCATGGTGCTGCTGCGCTGACAGGGCTGTGAGCAGCCGGCCTTCCG
CTCTCACCAGTTCCGCGTCGGAATAGACGGTCCTTCCCCGGGGAGTCAGTTCCTCCCCGGGCCCCTGAGCCATGCCCATCGCAGCCGCCC
CGAAGGAGCCAGGTGTAAATTAATTATTTGAAAGCAACTGAACAATGGAGCCAGACATCATTCGAATGTACTCTTCATCCCCACCACCAT
TAGACAATGGAGCAGAGGATGATGATGATGATGAATTTGGGGAATTTGGTGGGTTTTCAGAAGTTAGCCCTTCTGGTGTAGGGTTTGTTG
ATTTCGATACACCAGATTATACTCGTCCCAAGGAAGAGTTTGTACCTTCAAACCATTTTATGCCAATTCATGAATTCTCAGAAAATGTAG
ATAGCCTTACAAGCTTTAAGTCCATTAAAAATGGTAATGATAAGGACATCACTGCTGAACTTTCTGCTCCTGTGAAAGGACAGTCTGATG
TTTTACTTTCTACCACCAGCAAAGAAATAATTTCATCTGAAATGTTAGCTACTTCCATTGATGGCATGGAAAGACCAGGAAATTTAAATA
AAGTAGTGGAGCAGAGACAGAATGTTGGAACACTTGAAAGTTTCTCTCCAGGAGATTTTAGAACTAATATGAATGTTGTTCATCAAAACA
AGCAGTTAGAGAGCTGCAATGGTGAAAAGCCTCCTTGTCTGGAGATTCTAACAAATGGGTTTGCAGTGTTGGAAACTGTAAATCCTCAGG
GAACAGATGATCTGGACAATGTAGCTGATTCAAAGGGACGGAAGCCTCTTAGCACTCATAGCACTGAGTATAATTTAGACTCTGTACCTA
GTCCTGCTGAGGAATTTGCAGATTTTGCCACATTTTCCAAAAAGGAAAGGATACAATTAGAAGAAATAGAATGTGCAGTTTTAAATGATA
GAGAAGCACTAACCATTCGGGAAAACAATAAAATTAATAGAGTCAATGAACTGAATTCTGTAAAAGAAGTGGCTTTGGGTAGAAGCTTGG
ATAACAAAGGAGACACTGATGGAGAGGATCAGGTTTGTGTTTCAGAAATAAGCATAGTGACTAACAGAGGTTTCAGTGTTGAAAAACAAG
GCCTTCCAACACTGCAACAGGATGAATTTTTACAGTCAGGTGTTCAGTCAAAGGCTTGGAGTTTGGTAGACTCAGCTGATAATTCAGAAG
CCATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTACTTACTTCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTT
CTGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTTACTAATTTCCAAAGCCCAAACATTGACCCCACAGAAGAAAATGATT
TGGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGACTTTGTGACTTGCAATGATATCAATGAAGATGATTTTGGTGATTTTG
GTGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACTGGTACTCAAGATTCAATGAGTGATGCCACTTTTGAAGAGTCTTCAG
AGCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAATTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAA
CAAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAATGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTG
CAAAACTTAAAAATGGGCAAGAAGGTGAGATTGGACATTTTGATTCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTG
ATGATTTTGCAGACTTCAGTTCAGCTGGTCCTAGCCAAGTTGTAGATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGG
CTGCTTTTGGAGACCAGCAGGCTACTGAATCTCATCATCGAAAGGAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAG
GAACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAAAGGAGCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGA
CAGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTTCCTTCCATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGA
AGCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAGGCCTTACCTGAAAGTGGGGAATTGCTAGATGTGTGGACTGAGCTAC
AGGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGCTCCCATAGCAACAAGAAGCTTTTGTCCTCCTTGGGAATAGACACCC
GAAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTGCCCATGTATGCAGCAGGATTGGCCAAGAAGCTTGAGAGAAGAAAAA
TTTCAGAAAAATTGTCTCAATTTGACTAGAATATCAATGAACCAGGAAAACTGAAGCACCTTCCCTAAAGAAAACTTGGGTATACAATTA
CTCCACAGACAGAGCTGAGGGTTTTTTACCCAAATCAGTCACTGGATTTTGCTGCCTGATACGTGAATCTTCTTGGAATTTTTCTCATGT
GGATCTAAGGGGAATGCTTTATTATGGCTGCTGTTGTCCAACAGAACGACCTAGTATTTGAATTTGCTAGTAACGTCATGGAGGATGAAC
GACAGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCT
GTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCC
TTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCC
CTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCT
CATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGA
AGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAAT
ACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAAC
CTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGT
ATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTT
CATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAAC
CAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTC
CATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGC
AGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGC
AGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTA
TTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAA
TTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCAT
CCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTA
TCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGC
AGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCA
ACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATA
AATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTC
TTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGC
TATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAG
GCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCT
TTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATT
GGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTAT
GTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGT
TCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAAT
GTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAA
CTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACT
CTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGAT
CATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACT
TTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAA
AAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTC
TAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGA

>2747_2747_1_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000238855_ELF1_chr13_41556418_ENST00000442101_length(amino acids)=774AA_BP=757
MEPDIIRMYSSSPPPLDNGAEDDDDDEFGEFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPSNHFMPIHEFSENVDSLTSFKSIKNGNDK
DITAELSAPVKGQSDVLLSTTSKEIISSEMLATSIDGMERPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVVHQNKQLESCNGEKPPCLE
ILTNGFAVLETVNPQGTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAEEFADFATFSKKERIQLEEIECAVLNDREALTIRENNKINRV
NELNSVKEVALGRSLDNKGDTDGEDQVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSGVQSKAWSLVDSADNSEAIRREQCKTEEKLDL
LTSKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQSPNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINEDDFGDFGDFGSASGSTPPFVT
GTQDSMSDATFEESSEHFPHFSEPGDDFGEFGDINAVSCQEETILTKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLKNGQEGEIGHFD
SVPNIQDDCNGFQDSDDFADFSSAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATESHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSKG
AVASGHLQESATSVQTALLNRLERIFEACFPSILVPDAEEEVTSLKHLLETSTLPIKTREALPESGELLDVWTELQDIHDAHGLRYQWGG

--------------------------------------------------------------
>2747_2747_2_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000238856_ELF1_chr13_41556418_ENST00000442101_length(transcript)=6106nt_BP=2585nt
GCATGATGGGAGAGTGTGTGGAGTGGGCGGGGGGTCTCCGCGGAGGAGGTGGAGGAGGCGGCGGCGGCGGCGGAAGAGGGCGGAGGGTAG
TGGGATGGGGGTCCCGCGGCAGCGGTGAAACTCCGGGTGGGCGTCCATGGTGCTGCTGCGCTGACAGGGCTGTGAGCAGCCGGCCTTCCG
CTCTCACCAGTTCCGCGTCGGAATAGACGGTCCTTCCCCGGGGAGTCAGTTCCTCCCCGGGCCCCTGAGCCATGCCCATCGCAGCCGCCC
CGAAGGAGCCAGGTGTAAATTAATTATTTGAAAGCAACTGAACAATGGAGCCAGACATCATTCGAATGTACTCTTCATCCCCACCACCAT
TAGACAATGGAGCAGAGGATGATGATGATGATGAATTTGGGGAATTTGGTGGGTTTTCAGAAGTTAGCCCTTCTGGTGTAGGGTTTGTTG
ATTTCGATACACCAGATTATACTCGTCCCAAGGAAGAGTTTGTACCTTCAAACCATTTTATGCCAATTCATGAATTCTCAGAAAATGTAG
ATAGCCTTACAAGCTTTAAGTCCATTAAAAATGGTAATGATAAGGACATCACTGCTGAACTTTCTGCTCCTGTGAAAGGACAGTCTGATG
TTTTACTTTCTACCACCAGCAAAGAAATAATTTCATCTGAAATGTTAGCTACTTCCATTGATGGCATGGAAAGACCAGGAAATTTAAATA
AAGTAGTGGAGCAGAGACAGAATGTTGGAACACTTGAAAGTTTCTCTCCAGGAGATTTTAGAACTAATATGAATGTTGTTCATCAAAACA
AGCAGTTAGAGAGCTGCAATGGTGAAAAGCCTCCTTGTCTGGAGATTCTAACAAATGGGTTTGCAGTGTTGGAAACTGTAAATCCTCAGG
GAACAGATGATCTGGACAATGTAGCTGATTCAAAGGGACGGAAGCCTCTTAGCACTCATAGCACTGAGTATAATTTAGACTCTGTACCTA
GTCCTGCTGAGGAATTTGCAGATTTTGCCACATTTTCCAAAAAGGAAAGGATACAATTAGAAGAAATAGAATGTGCAGTTTTAAATGATA
GAGAAGCACTAACCATTCGGGAAAACAATAAAATTAATAGAGTCAATGAACTGAATTCTGTAAAAGAAGTGGCTTTGGGTAGAAGCTTGG
ATAACAAAGGAGACACTGATGGAGAGGATCAGGTTTGTGTTTCAGAAATAAGCATAGTGACTAACAGAGGTTTCAGTGTTGAAAAACAAG
GCCTTCCAACACTGCAACAGGATGAATTTTTACAGTCAGGTGTTCAGTCAAAGGCTTGGAGTTTGGTAGACTCAGCTGATAATTCAGAAG
CCATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTACTTACTTCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTT
CTGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTTACTAATTTCCAAAGCCCAAACATTGACCCCACAGAAGAAAATGATT
TGGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGACTTTGTGACTTGCAATGATATCAATGAAGATGATTTTGGTGATTTTG
GTGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACTGGTACTCAAGATTCAATGAGTGATGCCACTTTTGAAGAGTCTTCAG
AGCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAATTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAA
CAAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAATGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTG
CAAAACTTAAAAATGGGCAAGAAGGTGAGATTGGACATTTTGATTCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTG
ATGATTTTGCAGACTTCAGTTCAGCTGGTCCTAGCCAAGTTGTAGATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGG
CTGCTTTTGGAGACCAGCAGGCTACTGAATCTCATCATCGAAAGGAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAG
GAACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAAAGGAGCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGA
CAGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTTCCTTCCATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGA
AGCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAGGCCTTACCTGAAAGTGGGGAATTGCTAGATGTGTGGACTGAGCTAC
AGGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGCTCCCATAGCAACAAGAAGCTTTTGTCCTCCTTGGGAATAGACACCC
GAAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTGCCCATGTATGCAGCAGGATTGGCCAAGAAGCTTGAGAGAAGAAAAA
TTTCAGAAAAATTGTCTCAATTTGACTAGAATATCAATGAACCAGGAAAACTGAAGCACCTTCCCTAAAGAAAACTTGGGTATACAATTA
CTCCACAGACAGAGCTGAGGGTTTTTTACCCAAATCAGTCACTGGATTTTGCTGCCTGATACGTGAATCTTCTTGGAATTTTTCTCATGT
GGATCTAAGGGGAATGCTTTATTATGGCTGCTGTTGTCCAACAGAACGACCTAGTATTTGAATTTGCTAGTAACGTCATGGAGGATGAAC
GACAGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCT
GTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCC
TTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCC
CTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCT
CATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGA
AGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAAT
ACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAAC
CTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGT
ATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTT
CATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAAC
CAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTC
CATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGC
AGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGC
AGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTA
TTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAA
TTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCAT
CCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTA
TCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGC
AGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCA
ACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATA
AATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTC
TTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGC
TATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAG
GCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCT
TTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATT
GGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTAT
GTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGT
TCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAAT
GTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAA
CTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACT
CTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGAT
CATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACT
TTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAA
AAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTC
TAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGA

>2747_2747_2_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000238856_ELF1_chr13_41556418_ENST00000442101_length(amino acids)=774AA_BP=757
MEPDIIRMYSSSPPPLDNGAEDDDDDEFGEFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPSNHFMPIHEFSENVDSLTSFKSIKNGNDK
DITAELSAPVKGQSDVLLSTTSKEIISSEMLATSIDGMERPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVVHQNKQLESCNGEKPPCLE
ILTNGFAVLETVNPQGTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAEEFADFATFSKKERIQLEEIECAVLNDREALTIRENNKINRV
NELNSVKEVALGRSLDNKGDTDGEDQVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSGVQSKAWSLVDSADNSEAIRREQCKTEEKLDL
LTSKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQSPNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINEDDFGDFGDFGSASGSTPPFVT
GTQDSMSDATFEESSEHFPHFSEPGDDFGEFGDINAVSCQEETILTKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLKNGQEGEIGHFD
SVPNIQDDCNGFQDSDDFADFSSAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATESHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSKG
AVASGHLQESATSVQTALLNRLERIFEACFPSILVPDAEEEVTSLKHLLETSTLPIKTREALPESGELLDVWTELQDIHDAHGLRYQWGG

--------------------------------------------------------------
>2747_2747_3_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000409183_ELF1_chr13_41556418_ENST00000442101_length(transcript)=4755nt_BP=1234nt
CATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTACTTACTTCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTTC
TGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTTACTAATTTCCAAAGCCCAAACATTGACCCCACAGAAGAAAATGATTT
GGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGACTTTGTGACTTGCAATGATATCAATGAAGATGATTTTGGTGATTTTGG
TGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACTGGTACTCAAGATTCAATGAGTGATGCCACTTTTGAAGAGTCTTCAGA
GCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAATTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAAC
AAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAATGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTGC
AAAACTTAAAAATGGGCAAGAAGGTGAGATTGGACATTTTGATTCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTGA
TGATTTTGCAGACTTCAGTTCAGCTGGTCCTAGCCAAGTTGTAGATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGGC
TGCTTTTGGAGACCAGCAGGCTACTGAATCTCATCATCGAAAGGAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAGG
AACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAAAGGAGCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGAC
AGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTTCCTTCCATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGAA
GCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAGGCCTTACCTGAAAGTGGGGAATTGCTAGATGTGTGGACTGAGCTACA
GGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGCTCCCATAGCAACAAGAAGCTTTTGTCCTCCTTGGGAATAGACACCCG
AAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTGCCCATGTATGCAGCAGGATTGGCCAAGAAGCTTGAGAGAAGAAAAAT
TTCAGAAAAATTGTCTCAATTTGACTAGAATATCAATGAACCAGGAAAACTGAAGCACCTTCCCTAAAGAAAACTTGGGTATACAATTAC
TCCACAGACAGAGCTGAGGGTTTTTTACCCAAATCAGTCACTGGATTTTGCTGCCTGATACGTGAATCTTCTTGGAATTTTTCTCATGTG
GATCTAAGGGGAATGCTTTATTATGGCTGCTGTTGTCCAACAGAACGACCTAGTATTTGAATTTGCTAGTAACGTCATGGAGGATGAACG
ACAGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCTG
TGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCCT
TACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCCC
TATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCTC
ATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGAA
GAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAATA
CATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAACC
TGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTA
TCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTTC
ATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAACC
AGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCC
ATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGCA
GGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCA
GTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTAT
TTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAAT
TGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCATC
CTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTAT
CAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGCA
GCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCAA
CTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATAA
ATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTCT
TTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGCT
ATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAGG
CAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCTT
TGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATTG
GAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTATG
TAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGTT
CTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAATG
TTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAAC
TCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACTC
TTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGATC
ATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACTT
TTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAAA
AAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTCT
AAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAA

>2747_2747_3_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000409183_ELF1_chr13_41556418_ENST00000442101_length(amino acids)=595AA_BP=
MAAVVQQNDLVFEFASNVMEDERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCH
DGDETIETIEAAEALLNMDSPGPMLDEKRINGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGK
GNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPK
DLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFR
TVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSS
QPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKT

--------------------------------------------------------------
>2747_2747_4_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000409933_ELF1_chr13_41556418_ENST00000442101_length(transcript)=5792nt_BP=2271nt
ATGGAGCCAGACATCATTCGAATGTACTCTTCATCCCCACCACCATTAGACAATGGAGCAGAGGATGATGATGATGATGAATTTGGGGAA
TTTGGTGGGTTTTCAGAAGTTAGCCCTTCTGGTGTAGGGTTTGTTGATTTCGATACACCAGATTATACTCGTCCCAAGGAAGAGTTTGTA
CCTTCAAACCATTTTATGCCAATTCATGAATTCTCAGAAAATGTAGATAGCCTTACAAGCTTTAAGTCCATTAAAAATGGTAATGATAAG
GACATCACTGCTGAACTTTCTGCTCCTGTGAAAGGACAGTCTGATGTTTTACTTTCTACCACCAGCAAAGAAATAATTTCATCTGAAATG
TTAGCTACTTCCATTGATGGCATGGAAAGACCAGGAAATTTAAATAAAGTAGTGGAGCAGAGACAGAATGTTGGAACACTTGAAAGTTTC
TCTCCAGGAGATTTTAGAACTAATATGAATGTTGTTCATCAAAACAAGCAGTTAGAGAGCTGCAATGGTGAAAAGCCTCCTTGTCTGGAG
ATTCTAACAAATGGGTTTGCAGTGTTGGAAACTGTAAATCCTCAGGGAACAGATGATCTGGACAATGTAGCTGATTCAAAGGGACGGAAG
CCTCTTAGCACTCATAGCACTGAGTATAATTTAGACTCTGTACCTAGTCCTGCTGAGGAATTTGCAGATTTTGCCACATTTTCCAAAAAG
GAAAGGATACAATTAGAAGAAATAGAATGTGCAGTTTTAAATGATAGAGAAGCACTAACCATTCGGGAAAACAATAAAATTAATAGAGTC
AATGAACTGAATTCTGTAAAAGAAGTGGCTTTGGGTAGAAGCTTGGATAACAAAGGAGACACTGATGGAGAGGATCAGGTTTGTGTTTCA
GAAATAAGCATAGTGACTAACAGAGGTTTCAGTGTTGAAAAACAAGGCCTTCCAACACTGCAACAGGATGAATTTTTACAGTCAGGTGTT
CAGTCAAAGGCTTGGAGTTTGGTAGACTCAGCTGATAATTCAGAAGCCATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTA
CTTACTTCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTTCTGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTT
ACTAATTTCCAAAGCCCAAACATTGACCCCACAGAAGAAAATGATTTGGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGAC
TTTGTGACTTGCAATGATATCAATGAAGATGATTTTGGTGATTTTGGTGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACT
GGTACTCAAGATTCAATGAGTGATGCCACTTTTGAAGAGTCTTCAGAGCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAA
TTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAACAAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAA
TGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTGCAAAACTTAAAAATGGGCAAGAAGGTGAGATTGGACATTTTGAT
TCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTGATGATTTTGCAGACTTCAGTTCAGCTGGTCCTAGCCAAGTTGTA
GATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGGCTGCTTTTGGAGACCAGCAGGCTACTGAATCTCATCATCGAAAG
GAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAGGAACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAAAGGA
GCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGACAGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTT
CCTTCCATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGAAGCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAG
GCCTTACCTGAAAGTGGGGAATTGCTAGATGTGTGGACTGAGCTACAGGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGC
TCCCATAGCAACAAGAAGCTTTTGTCCTCCTTGGGAATAGACACCCGAAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTG
CCCATGTATGCAGCAGGATTGGCCAAGAAGCTTGAGAGAAGAAAAATTTCAGAAAAATTGTCTCAATTTGACTAGAATATCAATGAACCA
GGAAAACTGAAGCACCTTCCCTAAAGAAAACTTGGGTATACAATTACTCCACAGACAGAGCTGAGGGTTTTTTACCCAAATCAGTCACTG
GATTTTGCTGCCTGATACGTGAATCTTCTTGGAATTTTTCTCATGTGGATCTAAGGGGAATGCTTTATTATGGCTGCTGTTGTCCAACAG
AACGACCTAGTATTTGAATTTGCTAGTAACGTCATGGAGGATGAACGACAGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAA
CATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCTGTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGAT
GTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCCTTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAA
ACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCCCTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATG
GAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCTCATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAA
CCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGAAGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGG
GAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAATACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTG
GATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAACCTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTAT
TACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGTATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGAT
GAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTTCATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTA
TCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAACCAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTT
GCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTCCATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCA
GTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGCAGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATA
CAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGCAGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTT
ATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTATTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAA
GAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAATTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAAT
GTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCATCCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGT
TCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTATCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAA
AAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGCAGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGA
TTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCAACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGT
TAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATAAATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGT
TAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTCTTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGC
ATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGCTATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTG
TATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAGGCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGT
AAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCTTTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGC
ACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATTGGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATA
GTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTATGTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAA
GAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGTTCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCA
ATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAATGTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTA
TGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAACTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGT
TGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACTCTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCT
GGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGATCATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGA
TAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACTTTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAA
TGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAAAAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTA
CAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTCTAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCA
TATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGAATAAGTGTGCAGAGAATATTACTAGAACATCAGCATTACTTAAT

>2747_2747_4_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000409933_ELF1_chr13_41556418_ENST00000442101_length(amino acids)=774AA_BP=757
MEPDIIRMYSSSPPPLDNGAEDDDDDEFGEFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPSNHFMPIHEFSENVDSLTSFKSIKNGNDK
DITAELSAPVKGQSDVLLSTTSKEIISSEMLATSIDGMERPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVVHQNKQLESCNGEKPPCLE
ILTNGFAVLETVNPQGTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAEEFADFATFSKKERIQLEEIECAVLNDREALTIRENNKINRV
NELNSVKEVALGRSLDNKGDTDGEDQVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSGVQSKAWSLVDSADNSEAIRREQCKTEEKLDL
LTSKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQSPNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINEDDFGDFGDFGSASGSTPPFVT
GTQDSMSDATFEESSEHFPHFSEPGDDFGEFGDINAVSCQEETILTKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLKNGQEGEIGHFD
SVPNIQDDCNGFQDSDDFADFSSAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATESHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSKG
AVASGHLQESATSVQTALLNRLERIFEACFPSILVPDAEEEVTSLKHLLETSTLPIKTREALPESGELLDVWTELQDIHDAHGLRYQWGG

--------------------------------------------------------------
>2747_2747_5_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000422803_ELF1_chr13_41556418_ENST00000442101_length(transcript)=6106nt_BP=2585nt
GCATGATGGGAGAGTGTGTGGAGTGGGCGGGGGGTCTCCGCGGAGGAGGTGGAGGAGGCGGCGGCGGCGGCGGAAGAGGGCGGAGGGTAG
TGGGATGGGGGTCCCGCGGCAGCGGTGAAACTCCGGGTGGGCGTCCATGGTGCTGCTGCGCTGACAGGGCTGTGAGCAGCCGGCCTTCCG
CTCTCACCAGTTCCGCGTCGGAATAGACGGTCCTTCCCCGGGGAGTCAGTTCCTCCCCGGGCCCCTGAGCCATGCCCATCGCAGCCGCCC
CGAAGGAGCCAGGTGTAAATTAATTATTTGAAAGCAACTGAACAATGGAGCCAGACATCATTCGAATGTACTCTTCATCCCCACCACCAT
TAGACAATGGAGCAGAGGATGATGATGATGATGAATTTGGGGAATTTGGTGGGTTTTCAGAAGTTAGCCCTTCTGGTGTAGGGTTTGTTG
ATTTCGATACACCAGATTATACTCGTCCCAAGGAAGAGTTTGTACCTTCAAACCATTTTATGCCAATTCATGAATTCTCAGAAAATGTAG
ATAGCCTTACAAGCTTTAAGTCCATTAAAAATGGTAATGATAAGGACATCACTGCTGAACTTTCTGCTCCTGTGAAAGGACAGTCTGATG
TTTTACTTTCTACCACCAGCAAAGAAATAATTTCATCTGAAATGTTAGCTACTTCCATTGATGGCATGGAAAGACCAGGAAATTTAAATA
AAGTAGTGGAGCAGAGACAGAATGTTGGAACACTTGAAAGTTTCTCTCCAGGAGATTTTAGAACTAATATGAATGTTGTTCATCAAAACA
AGCAGTTAGAGAGCTGCAATGGTGAAAAGCCTCCTTGTCTGGAGATTCTAACAAATGGGTTTGCAGTGTTGGAAACTGTAAATCCTCAGG
GAACAGATGATCTGGACAATGTAGCTGATTCAAAGGGACGGAAGCCTCTTAGCACTCATAGCACTGAGTATAATTTAGACTCTGTACCTA
GTCCTGCTGAGGAATTTGCAGATTTTGCCACATTTTCCAAAAAGGAAAGGATACAATTAGAAGAAATAGAATGTGCAGTTTTAAATGATA
GAGAAGCACTAACCATTCGGGAAAACAATAAAATTAATAGAGTCAATGAACTGAATTCTGTAAAAGAAGTGGCTTTGGGTAGAAGCTTGG
ATAACAAAGGAGACACTGATGGAGAGGATCAGGTTTGTGTTTCAGAAATAAGCATAGTGACTAACAGAGGTTTCAGTGTTGAAAAACAAG
GCCTTCCAACACTGCAACAGGATGAATTTTTACAGTCAGGTGTTCAGTCAAAGGCTTGGAGTTTGGTAGACTCAGCTGATAATTCAGAAG
CCATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTACTTACTTCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTT
CTGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTTACTAATTTCCAAAGCCCAAACATTGACCCCACAGAAGAAAATGATT
TGGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGACTTTGTGACTTGCAATGATATCAATGAAGATGATTTTGGTGATTTTG
GTGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACTGGTACTCAAGATTCAATGAGTGATGCCACTTTTGAAGAGTCTTCAG
AGCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAATTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAA
CAAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAATGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTG
CAAAACTTAAAAATGGGCAAGAAGGTGAGATTGGACATTTTGATTCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTG
ATGATTTTGCAGACTTCAGTTCAGCTGGTCCTAGCCAAGTTGTAGATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGG
CTGCTTTTGGAGACCAGCAGGCTACTGAATCTCATCATCGAAAGGAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAG
GAACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAAAGGAGCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGA
CAGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTTCCTTCCATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGA
AGCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAGGCCTTACCTGAAAGTGGGGAATTGCTAGATGTGTGGACTGAGCTAC
AGGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGCTCCCATAGCAACAAGAAGCTTTTGTCCTCCTTGGGAATAGACACCC
GAAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTGCCCATGTATGCAGCAGGATTGGCCAAGAAGCTTGAGAGAAGAAAAA
TTTCAGAAAAATTGTCTCAATTTGACTAGAATATCAATGAACCAGGAAAACTGAAGCACCTTCCCTAAAGAAAACTTGGGTATACAATTA
CTCCACAGACAGAGCTGAGGGTTTTTTACCCAAATCAGTCACTGGATTTTGCTGCCTGATACGTGAATCTTCTTGGAATTTTTCTCATGT
GGATCTAAGGGGAATGCTTTATTATGGCTGCTGTTGTCCAACAGAACGACCTAGTATTTGAATTTGCTAGTAACGTCATGGAGGATGAAC
GACAGCTTGGTGATCCAGCTATTTTTCCTGCCGTAATTGTGGAACATGTTCCTGGTGCTGATATTCTCAATAGTTATGCCGGTCTAGCCT
GTGTGGAAGAGCCCAATGACATGATTACTGAGAGTTCACTGGATGTTGCTGAAGAAGAAATCATAGACGATGATGATGATGACATCACCC
TTACAGTTGAAGCTTCTTGTCATGACGGGGATGAAACAATTGAAACTATTGAGGCTGCTGAGGCACTCCTCAATATGGATTCCCCTGGCC
CTATGCTGGATGAAAAACGAATAAATGGGATTCCTGAAGTGATGGAAACACAGCAGGTGCAAGAAAAATATGCAGACTCACCGGGAGCCT
CATCACCAGAACAGCCTAAGAGGAAAAAAGGAAGAAAAACTAAACCACCACGACCAGATTCCCCAGCCACTACGCCAAATATATCTGTGA
AGAAGAAAAACAAAGATGGAAAGGGAAACACAATTTATCTTTGGGAGTTTTTACTGGCACTGCTCCAGGACAAGGCTACTTGTCCTAAAT
ACATCAAGTGGACCCAGCGAGAGAAAGGCATTTTTAAATTGGTGGATTCTAAAGCAGTGTCCAGGTTGTGGGGGAAGCACAAAAACAAAC
CTGATATGAATTATGAGACCATGGGAAGAGCACTCAGGTACTATTACCAAAGGGGTATTCTGGCAAAAGTGGAAGGTCAGCGCTTGGTGT
ATCAGTTTAAAGAAATGCCAAAAGATCTTATATATATAAATGATGAGGATCCAAGTTCCAGCATAGAGTCTTCAGATCCATCGCTATCTT
CATCAGCCACTTCAAATAGGAATCAAACCAGCCGGTCGAGAGTATCTTCAAGTCCAGGGGTAAAAGGAGGAGCCACTACAGTTCTAAAAC
CAGGGAATTCTAAAGCTGCAAAACCCAAAGATCCTGTGGAAGTTGCACAACCATCAGAAGTTTTGAGGACAGTGCAGCCCACGCAGTCTC
CATATCCTACCCAGCTCTTCCGGACTGTTCATGTAGTACAGCCAGTACAGGCTGTCCCAGAGGGAGAAGCAGCTAGAACCAGTACCATGC
AGGATGAAACATTAAATTCTTCCGTTCAGAGTATTAGGACTATACAGGCTCCAACCCAAGTTCCAGTGGTTGTGTCTCCTAGGAATCAGC
AGTTGCATACAGTAACACTCCAAACAGTGCCACTCACAACAGTTATAGCCAGCACAGATCCATCAGCAGGTACTGGATCTCAGAAGTTTA
TTTTACAAGCCATTCCATCATCACAGCCCATGACAGTACTGAAAGAAAATGTCATGCTGCAGTCACAAAAGGCGGGCTCTCCTCCTTCAA
TTGTCTTGGGCCCTGCCCAGGTTCAGCAGGTCCTTACTAGCAATGTTCAGACCATTTGCAATGGAACCGTCAGTGTGGCTTCCTCTCCAT
CCTTCAGTGCTACTGCACCTGTGGTGACCTTTTCTCCTCGCAGTTCACAGCTGGTTGCTCACCCACCTGGCACTGTAATCACTTCAGTTA
TCAAAACTCAAGAAACAAAAACTCTTACACAGGAAGTAGAGAAAAAGGAATCTGAAGATCATTTGAAAGAGAACACTGAGAAAACGGAGC
AGCAGCCACAGCCTTATGTGATGGTAGTGTCCAGTTCCAATGGATTTACTTCTCAGGTAGCTATGAAACAAAACGAACTGCTGGAACCCA
ACTCTTTTTAGTTAATATACCAAAGCTTATGAATAATTGTTTGTTAATTGAACATTTTCAATTATATGCAGACTGACTGATTCTAAGATA
AATTCTAAGGAGGTTTCTAATTTTGTAATTGTTAAAAATAGAGTTAATTTTGACTTTGTTAGATGAGGGAGGAAAACTCAACTGTTTCTC
TTTGTTATCTAAATGTTTCAGAATTCAATCGTGAAGGAACAGGCATTTTACACTATGAAGACATTCTTTTGAGATTTTTATTTCAGTTGC
TATATCATAAGCATTTTTAAAGTTTCTTTTCTAATTTTACATTGTATTAGATTTTCTGATTCTTTTGTAAATACAGAACTTAAATAGAAG
GCAACAGGAAATTTATATAGGAACTATTTTCATTCCACTTGTGTAAGTTAAGTCTTGACTCTTTCAAATGCAAAAAACCTATTTTATGCT
TTGTTAAAATTATGGTGTCACTTAGATTGACTTTAGTTGACTGCACTATATAATATAGAACTATGAATATGTAGAATAACATGAAAAATT
GGAGGTGCTGGTGGTATGGCTGACCCTGTTTCAGAAGCAGGATAGTATAAAAGCATCAGCCTAAGAATGGCACTCCCACTAACTAGCTAT
GTAATCTTGACCTCTTTGGGCTTTAGTTCCTCTCATAAAAGGAAGAGATGTATTGGATTAGACTAGATGATCACCACTTTCTCTTCTAGT
TCTAATTTTTTTAATTCTAATACCTATATTTTCAAGTTATGTCAATTAAATCATTATCAGGTTATTTCCTAATGTAAGAATAGCTAAAAT
GTTGCAGAGAAATAAGTGACCCAACAAAATTTATTCATCTGTTATGGGTAAGATCTGCCATAAATTCTTCCTAAATAATTTGTTTACTAA
CTCTTTAGGCCACTGTGCTTTGCGGTCCATTAGTAAACTTGTGTTGCTAAGTGCTAAACAGAATACTGCTATTTTGAGAGAGTCAAGACT
CTTTCTTAAGGGCCAAGAAAGCAACTTGAGCCTTGGGCTAATCTGGCTGAGTAGTCAGTTATAAAAGCATAATTGCTTTATATTTTGGAT
CATTTTTTACTGGGGGCGGACTTGGGGGGGGTTGCATACAAAGATAACATATATATCCAACTTTCTGAAATGAAATGTTTTTAGATTACT
TTTTCAACTGTAAATAATGTACATTTAATGTCACAAGAAAAAAATGTCTTCTGCAAATTTTCTAGTATAACAGAAATTTTTGTAGATGAA
AAAAATCATTATGTTTAGAGGTCTAATGCTATGTTTTCATATTACAGAGTGAATTTGTATTTAAACAAAAATTTAAATTTTGGAATCCTC
TAAACATTTTTGTATCTTTAATTGGTTTATTATTAAATAAATCATATAAAAATTCTCAGTGTCTGTTTTCAGGCAAAAGTTTCTTAAAGA

>2747_2747_5_AFTPH-ELF1_AFTPH_chr2_64796813_ENST00000422803_ELF1_chr13_41556418_ENST00000442101_length(amino acids)=774AA_BP=757
MEPDIIRMYSSSPPPLDNGAEDDDDDEFGEFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPSNHFMPIHEFSENVDSLTSFKSIKNGNDK
DITAELSAPVKGQSDVLLSTTSKEIISSEMLATSIDGMERPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVVHQNKQLESCNGEKPPCLE
ILTNGFAVLETVNPQGTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAEEFADFATFSKKERIQLEEIECAVLNDREALTIRENNKINRV
NELNSVKEVALGRSLDNKGDTDGEDQVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSGVQSKAWSLVDSADNSEAIRREQCKTEEKLDL
LTSKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQSPNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINEDDFGDFGDFGSASGSTPPFVT
GTQDSMSDATFEESSEHFPHFSEPGDDFGEFGDINAVSCQEETILTKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLKNGQEGEIGHFD
SVPNIQDDCNGFQDSDDFADFSSAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATESHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSKG
AVASGHLQESATSVQTALLNRLERIFEACFPSILVPDAEEEVTSLKHLLETSTLPIKTREALPESGELLDVWTELQDIHDAHGLRYQWGG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AFTPH-ELF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238855+5101_523757.0937.0AP1G1%2C AP1G2%2C GGA1 and GGA3
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238856+591_523757.0910.0AP1G1%2C AP1G2%2C GGA1 and GGA3
HgeneAFTPHchr2:64796813chr13:41556418ENST00000409933+491_523757.0937.0AP1G1%2C AP1G2%2C GGA1 and GGA3
HgeneAFTPHchr2:64796813chr13:41556418ENST00000422803+5101_523757.0938.0AP1G1%2C AP1G2%2C GGA1 and GGA3
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238855+510386_610757.0937.0AP1G1
HgeneAFTPHchr2:64796813chr13:41556418ENST00000238856+59386_610757.0910.0AP1G1
HgeneAFTPHchr2:64796813chr13:41556418ENST00000409933+49386_610757.0937.0AP1G1
HgeneAFTPHchr2:64796813chr13:41556418ENST00000422803+510386_610757.0938.0AP1G1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AFTPH-ELF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AFTPH-ELF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource