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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ESR1-C6orf211 (FusionGDB2 ID:27537)

Fusion Gene Summary for ESR1-C6orf211

check button Fusion gene summary
Fusion gene informationFusion gene name: ESR1-C6orf211
Fusion gene ID: 27537
HgeneTgene
Gene symbol

ESR1

C6orf211

Gene ID

2099

79624

Gene nameestrogen receptor 1acidic residue methyltransferase 1
SynonymsER|ESR|ESRA|ESTRR|Era|NR3A1C6orf211
Cytomap

6q25.1-q25.2

6q25.1

Type of geneprotein-codingprotein-coding
Descriptionestrogen receptorE2 receptor alphaER-alphaestradiol receptorestrogen nuclear receptor alphaestrogen receptor alpha E1-E2-1-2estrogen receptor alpha E1-N2-E2-1-2nuclear receptor subfamily 3 group A member 1oestrogen receptor alphadamage-control phosphatase ARMT1UPF0364 protein C6orf211protein-glutamate O-methyltransferasesugar phosphate phosphatase ARMT1
Modification date2020032920200313
UniProtAcc

P03372

.
Ensembl transtripts involved in fusion geneENST00000206249, ENST00000338799, 
ENST00000406599, ENST00000440973, 
ENST00000443427, ENST00000456483, 
ENST00000427531, ENST00000482101, 
ENST00000483931, ENST00000545879, 
ENST00000367294, 
Fusion gene scores* DoF score21 X 18 X 8=30243 X 3 X 4=36
# samples 354
** MAII scorelog2(35/3024*10)=-3.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ESR1 [Title/Abstract] AND C6orf211 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointESR1(152023140)-C6orf211(151785588), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneESR1

GO:0006366

transcription by RNA polymerase II

15831516

HgeneESR1

GO:0010629

negative regulation of gene expression

21695196

HgeneESR1

GO:0030520

intracellular estrogen receptor signaling pathway

9841876

HgeneESR1

GO:0032355

response to estradiol

15304487

HgeneESR1

GO:0043124

negative regulation of I-kappaB kinase/NF-kappaB signaling

7651415|16043358

HgeneESR1

GO:0043433

negative regulation of DNA-binding transcription factor activity

10816575

HgeneESR1

GO:0043627

response to estrogen

11581164

HgeneESR1

GO:0045893

positive regulation of transcription, DNA-templated

9841876|20074560

HgeneESR1

GO:0045899

positive regulation of RNA polymerase II transcriptional preinitiation complex assembly

9841876

HgeneESR1

GO:0045944

positive regulation of transcription by RNA polymerase II

11544182|12047722|15345745|15831516|18563714

HgeneESR1

GO:0051091

positive regulation of DNA-binding transcription factor activity

9328340|10681512

HgeneESR1

GO:0071392

cellular response to estradiol stimulus

15831516

TgeneC6orf211

GO:0032259

methylation

25732820


check buttonFusion gene breakpoints across ESR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C6orf211 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A1NA-01AESR1chr6

152023140

-C6orf211chr6

151785588

+
ChimerDB4BRCATCGA-E9-A1NA-01AESR1chr6

152023140

+C6orf211chr6

151785588

+
ChimerDB4OVTCGA-23-1111-01AESR1chr6

152129499

+C6orf211chr6

151775683

+


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Fusion Gene ORF analysis for ESR1-C6orf211

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000206249ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-3UTRENST00000338799ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-3UTRENST00000406599ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-3UTRENST00000440973ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-3UTRENST00000443427ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-3UTRENST00000456483ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-intronENST00000206249ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-intronENST00000338799ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-intronENST00000406599ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-intronENST00000440973ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-intronENST00000443427ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+
5CDS-intronENST00000456483ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+
5UTR-3CDSENST00000440973ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
5UTR-3CDSENST00000440973ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
5UTR-3UTRENST00000440973ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
In-frameENST00000206249ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
In-frameENST00000338799ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
In-frameENST00000406599ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
In-frameENST00000440973ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
In-frameENST00000443427ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
In-frameENST00000456483ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
intron-3CDSENST00000206249ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000206249ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000338799ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000338799ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000406599ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000406599ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000427531ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000427531ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
intron-3CDSENST00000427531ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000443427ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000443427ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000456483ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000456483ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000482101ENST00000367294ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3CDSENST00000482101ENST00000367294ESR1chr6

152129499

+C6orf211chr6

151775683

+
intron-3CDSENST00000482101ENST00000545879ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000206249ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000338799ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000406599ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000427531ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000427531ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
intron-3UTRENST00000443427ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000456483ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000482101ENST00000483931ESR1chr6

152023140

+C6orf211chr6

151785588

+
intron-3UTRENST00000482101ENST00000483931ESR1chr6

152129499

+C6orf211chr6

151775683

+
intron-intronENST00000427531ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+
intron-intronENST00000482101ENST00000545879ESR1chr6

152129499

+C6orf211chr6

151775683

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000440973ESR1chr6152129499+ENST00000367294C6orf211chr6151775683+30988223702106578
ENST00000338799ESR1chr6152129499+ENST00000367294C6orf211chr6151775683+4188191214603196578
ENST00000456483ESR1chr6152129499+ENST00000367294C6orf211chr6151775683+29466702181954578
ENST00000443427ESR1chr6152129499+ENST00000367294C6orf211chr6151775683+29897132611997578
ENST00000206249ESR1chr6152129499+ENST00000367294C6orf211chr6151775683+30908143622098578
ENST00000406599ESR1chr6152129499+ENST00000367294C6orf211chr6151775683+29626862341970578

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000440973ENST00000367294ESR1chr6152129499+C6orf211chr6151775683+0.0003773670.9996226
ENST00000338799ENST00000367294ESR1chr6152129499+C6orf211chr6151775683+0.0003830760.99961686
ENST00000456483ENST00000367294ESR1chr6152129499+C6orf211chr6151775683+0.0003207630.9996792
ENST00000443427ENST00000367294ESR1chr6152129499+C6orf211chr6151775683+0.0003499870.99965
ENST00000206249ENST00000367294ESR1chr6152129499+C6orf211chr6151775683+0.0003159840.999684
ENST00000406599ENST00000367294ESR1chr6152129499+C6orf211chr6151775683+0.0003145850.9996854

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Fusion Genomic Features for ESR1-C6orf211


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ESR1chr6152023140+C6orf211chr6151785587+4.94E-060.9999951
ESR1chr6152129499+C6orf211chr6151775682+2.07E-060.999998
ESR1chr6152023140+C6orf211chr6151785587+4.94E-060.9999951
ESR1chr6152129499+C6orf211chr6151775682+2.07E-060.999998

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ESR1-C6orf211


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:152023140/chr6:151785588)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ESR1

P03372

.
FUNCTION: Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences. Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP. Can activate the transcriptional activity of TFF1. Also mediates membrane-initiated estrogen signaling involving various kinase cascades. Isoform 3 is involved in activation of NOS3 and endothelial nitric oxide production. Isoforms lacking one or several functional domains are thought to modulate transcriptional activity by competitive ligand or DNA binding and/or heterodimerization with the full-length receptor. Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3. Isoform 3 can bind to ERE and inhibit isoform 1. {ECO:0000269|PubMed:10681512, ECO:0000269|PubMed:10816575, ECO:0000269|PubMed:11477071, ECO:0000269|PubMed:11682626, ECO:0000269|PubMed:14764652, ECO:0000269|PubMed:15078875, ECO:0000269|PubMed:15891768, ECO:0000269|PubMed:16043358, ECO:0000269|PubMed:16617102, ECO:0000269|PubMed:16684779, ECO:0000269|PubMed:17922032, ECO:0000269|PubMed:17932106, ECO:0000269|PubMed:18247370, ECO:0000269|PubMed:19350539, ECO:0000269|PubMed:20074560, ECO:0000269|PubMed:20705611, ECO:0000269|PubMed:21330404, ECO:0000269|PubMed:22083956, ECO:0000269|PubMed:7651415, ECO:0000269|PubMed:9328340}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneC6orf211chr6:152129499chr6:151775683ENST0000036729405401_40413442.0MotifSubfamily III RTxK motif
TgeneC6orf211chr6:152129499chr6:151775683ENST0000036729405253_25413442.0RegionSubstrate binding
TgeneC6orf211chr6:152129499chr6:151775683ENST0000036729405367_37113442.0RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18185_250150596.0DNA bindingNuclear receptor
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29185_250150596.0DNA bindingNuclear receptor
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310185_250150596.0DNA bindingNuclear receptor
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29185_250150596.0DNA bindingNuclear receptor
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28185_250150484.0DNA bindingNuclear receptor
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18311_547150596.0DomainNR LBD
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29311_547150596.0DomainNR LBD
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310311_547150596.0DomainNR LBD
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29311_547150596.0DomainNR LBD
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28311_547150484.0DomainNR LBD
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18251_310150596.0RegionNote=Hinge
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18264_595150596.0RegionNote=Self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18311_595150596.0RegionNote=Transactivation AF-2
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29251_310150596.0RegionNote=Hinge
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29264_595150596.0RegionNote=Self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29311_595150596.0RegionNote=Transactivation AF-2
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310251_310150596.0RegionNote=Hinge
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310264_595150596.0RegionNote=Self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310311_595150596.0RegionNote=Transactivation AF-2
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29251_310150596.0RegionNote=Hinge
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29264_595150596.0RegionNote=Self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29311_595150596.0RegionNote=Transactivation AF-2
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28251_310150484.0RegionNote=Hinge
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28264_595150484.0RegionNote=Self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28311_595150484.0RegionNote=Transactivation AF-2
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18185_205150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18221_245150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29185_205150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29221_245150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310185_205150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310221_245150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29185_205150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29221_245150596.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28185_205150484.0Zinc fingerNR C4-type
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28221_245150484.0Zinc fingerNR C4-type


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Fusion Gene Sequence for ESR1-C6orf211


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27537_27537_1_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000206249_C6orf211_chr6_151775683_ENST00000367294_length(transcript)=3090nt_BP=814nt
GAGTTGTGCCTGGAGTGATGTTTAAGCCAATGTCAGGGCAAGGCAACAGTCCCTGGCCGTCCTCCAGCACCTTTGTAATGCATATGAGCT
CGGGAGACCAGTACTTAAAGTTGGAGGCCCGGGAGCCCAGGAGCTGGCGGAGGGCGTTCGTCCTGGGACTGCACTTGCTCCCGTCGGGTC
GCCCGGCTTCACCGGACCCGCAGGCTCCCGGGGCAGGGCCGGGGCCAGAGCTCGCGTGTCGGCGGGACATGCGCTGCGTCGCCTCTAACC
TCGGGCTGTGCTCTTTTTCCAGGTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGA
CCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGC
AGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCT
ACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCCTCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCG
GCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGCCGCCGCAGCTGTCGCCTT
TCCTGCAGCCCCACGGCCAGCAGGTGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCT
ACAGATCATTTGCATATCTTACAATTAAAGACAGAATACCACAGATCTTAACTAAGGTTATTGATACATTGCATCGACATAAAAGTGAAT
TTTTTGAGAAACACGGAGAGGAAGGCGTGGAAGCTGAAAAGAAAGCTATCTCTCTCCTTTCTAAATTACGGAATGAATTGCAAACAGATA
AACCATTTATCCCCTTGGTTGAGAAATTTGTTGATACTGATATATGGAATCAGTACCTAGAATATCAACAGAGTCTTTTAAATGAAAGTG
ATGGAAAATCAAGATGGTTCTACTCACCGTGGTTGTTGGTAGAATGTTACATGTATCGAAGAATTCATGAAGCAATTATCCAGAGTCCAC
CAATCGATTACTTTGATGTATTTAAAGAATCAAAAGAGCAAAATTTCTATGGGTCACAGGAATCCATCATTGCTTTATGTACTCACCTGC
AACAATTGATAAGAACTATTGAAGACCTAGATGAAAATCAGCTGAAAGATGAGTTTTTTAAACTTCTGCAGATTTCACTGTGGGGAAATA
AGTGTGATCTGTCTCTCTCAGGTGGAGAAAGTAGTTCTCAGAATACCAATGTACTAAATTCATTGGAAGACCTAAAACCTTTCATTTTAT
TGAATGATATGGAACATCTTTGGTCATTGCTTAGCAATTGCAAGAAAACAAGAGAAAAAGCTTCTGCTACTAGAGTGTATATTGTTCTCG
ATAATTCTGGATTTGAGCTTGTTACAGATTTAATATTAGCCGACTTCTTGTTGTCCTCTGAACTGGCTACTGAGGTTCATTTTTATGGAA
AAACAATTCCATGGTTTGTTTCTGATACTACTATACATGATTTTAATTGGTTAATTGAACAGGTAAAACACAGTAATCATAAGTGGATGT
CCAAGTGTGGGGCTGACTGGGAAGAGTATATTAAAATGGGTAAATGGGTTTACCACAATCATATATTTTGGACTCTGCCTCATGAGTACT
GTGCAATGCCTCAGGTTGCACCTGACTTATATGCTGAACTACAGAAGGCACATTTAATTTTATTCAAGGGTGATTTGAATTACAGGAAGT
TGACAGGTGACAGAAAATGGGAGTTTTCTGTTCCATTTCATCAGGCTCTGAATGGCTTCCATCCTGCACCACTCTGTACCATAAGAACAT
TAAAAGCTGAAATTCAGGTTGGTCTGCAGCCTGGGCAAGGGGAACAGCTCCTGGCCTCTGAGCCCAGCTGGTGGACCACTGGAAAATATG
GAATATTTCAGTACGATGGTCCCCTTTGACTTGATTTAGGAGCTCTCAGTTGCATAGAAAGATCTGGTGAGCACCTTTTCATCCCCAGAA
AAGGAGCACGTGAATTGAGTCGCCTGGCGGCTCTGTACGCGCTCAGGGAAGCTTAGCTTCTTGGTGCCCATCTACGTGCACTGGATGATT
TTTCTTTTGAACATTTTGCCCCACTACACTGTTTTGGGGATAGCTGGGTTAAGCAAGTTAAAGATATTTACATTTATATTGGAATTTTAG
CAACTTTTTTTCAGGTTAAATATATAATTTCAAGTGCTTTTAATGAACTTATTTTTAATTGGCTAGGGAGCAAAAAATAAGTGAGTTCTG
CTTTTAGTTAGTTAACCTTGTTCTTTTCTTAAATAGTACACTGCATGGTATTTAATATTCCAGGAAGCATGGGATTTTATTTTGCTTGAT
TTTGGGCACATGAAATAATAGCTCTAGGAAAATGCGCATCTTAATGACTCTTTGTAAAGAGAGGCATTTCTTACAACTGTGATGTTTGCT
TACATAAAAGTTACCTCATAAGTTAATTCTAACTTTTATTCTTGAATTTTATTTCATTTCAATAGCTTGTTTCATTTGCACGCCTTTGTA
TTTTGATTGACCTGTAGAATGGATGTTAGGAAACTCAAAATTGAACACAGTGAAACAAATGGTATTTGAAGAAATGTAATATCTTTTATA
TTCTATTTATGATATCCATAATCAAATGAGATTATTTTACCACATAAATGTTTTAAATATCAGATTTTTAGTTTGCAGTTTTAGGAAAAT
GCTTTAGATAGAAAAGGTTCTTATGCATTGAATTTGGAGTACTACCAACAATGAATGAATTTATTTTTTATATTCTTACACATTTTATTG
GTCATTGTCACAGATAGTAAATACTAAAAATTTCAGGTCAGTTTGTTTTGAAACTGAAATTGGAAATAAATCTGGAAATGTTTTGTTGCA

>27537_27537_1_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000206249_C6orf211_chr6_151775683_ENST00000367294_length(amino acids)=578AA_BP=148
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFG
SNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRSFAYLTIKDRIPQILTKVIDTLHRHKSEF
FEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPP
IDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILL
NDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMS
KCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTL

--------------------------------------------------------------
>27537_27537_2_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000338799_C6orf211_chr6_151775683_ENST00000367294_length(transcript)=4188nt_BP=1912nt
CTAGAGCATGGGTGGCCATTGTTGACCTACAGGAGGCACCACTGTCACCAACAAAGGGTAACAGTCTTTCTTTTCAATATTTATTTATAT
CCAGTATTTATTTTCAATACTGACTATGGAGAGAGCTCTCCTGTGCTCAAACACTGCAATACTGGGGGTCTTTCAAAGCACAAAAACATA
TATTTGCATGATGGCATCATTAACATTTTTATGGCTTTCTATTTCTTTTTTGTACTGGTCTCAAGAGCCACTCATAAATCTCTCAGTAAC
TGCATAGTGTCCCAGGGCCAGAGACCGGCCACTCCTGGCATTGTGATTAGAGTCATTTAATATCCAAGGTGGTGACTAATGTCTGGCAAC
AAAGCCTCCATTGGGTGTCATGTGTCCTGGGACCCTGAGCGTGGGCACTCTAGGAGCACCTCAGTATTGCGTGTTAGTACTATGGCCGAG
AGAATAGTTGAGAAAGTGGTCAAGAGGTGGATCCATGTGAACGCCACTGGGAAATGAGAGACCTCGTTCCCAATCACGGTCAGTGCAACT
CGAAAGCCTAAAATCAGTTTAAAACAAAGGTATCTACCTTTATCTTATGTTCATATCCTAGGCTTTTAATAATACGTATTTTTCACATGT
TTACAGAAAGCAGTCAACTGAGCTATTCATGGAAAGGTTTGTGGGTTTGGTTAACGAAGTGGAGGAGTATTACATTTCAGCTGGAAACAC
ATCCCTAGAATGCCAAAACATTTATTCCAAAGTCTGGTTTCCTGGTGCAATCGGAGGCATGGCAATGCCTCTGTTCAGAGACTGGGGGCT
AGGGCCAGTAAGGCATTTGATCCACATGTATCCCAGAAGGCTTTTATTGTTAAATTATATTCTTTCGGAAAAACCACCCATGTCCTATTT
TGTAAACTTGATATCCATACACTTTTGACTGGCATTCTATTTTAGCCGTAAGACTATGATTCACAGCAAGCCTGTTTTTCCTCTTGCTTG
GGGTGGCAGCAGAAAGCATAGGGTACTTTCCAGCCTCCAAGGGTAGGGGCAAAGGGGCTGGGGTTTCTCCTCCCCAGTACAGCTTTCTCT
GGCTGTGCCACACTGCTCCCTGTGAGCAGACAGCAAGTCTCCCCTCACTCCCCACTGCCATTCATCCAGCGCTGTGCAGTAGCCCAGCTG
CGTGTCTGCCGGGAGGGGCTGCCAAGTGCCCTGCCTACTGGCTGCTTCCCGAATCCCTGCCATTCCACGCACAAACACATCCACACACTC
TCTCTGCCTAGTTCACACACTGAGCCACTCGCACATGCGAGCACATTCCTTCCTTCCTTCTCACTCTCTCGGCCCTTGACTTCTACAAGC
CCATGGAACATTTCTGGAAAGACGTTCTTGATCCAGCAGGGTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCAC
CCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGATCCAAGGGAACGAGCTGG
AGCCCCTGAACCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACT
ACCCCGAGGGCGCCGCCTACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCCTCCCCTACGGCCCCGGGT
CTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGC
CGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCAGGTGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGG
CCGGCCCGCCGGCATTCTACAGATCATTTGCATATCTTACAATTAAAGACAGAATACCACAGATCTTAACTAAGGTTATTGATACATTGC
ATCGACATAAAAGTGAATTTTTTGAGAAACACGGAGAGGAAGGCGTGGAAGCTGAAAAGAAAGCTATCTCTCTCCTTTCTAAATTACGGA
ATGAATTGCAAACAGATAAACCATTTATCCCCTTGGTTGAGAAATTTGTTGATACTGATATATGGAATCAGTACCTAGAATATCAACAGA
GTCTTTTAAATGAAAGTGATGGAAAATCAAGATGGTTCTACTCACCGTGGTTGTTGGTAGAATGTTACATGTATCGAAGAATTCATGAAG
CAATTATCCAGAGTCCACCAATCGATTACTTTGATGTATTTAAAGAATCAAAAGAGCAAAATTTCTATGGGTCACAGGAATCCATCATTG
CTTTATGTACTCACCTGCAACAATTGATAAGAACTATTGAAGACCTAGATGAAAATCAGCTGAAAGATGAGTTTTTTAAACTTCTGCAGA
TTTCACTGTGGGGAAATAAGTGTGATCTGTCTCTCTCAGGTGGAGAAAGTAGTTCTCAGAATACCAATGTACTAAATTCATTGGAAGACC
TAAAACCTTTCATTTTATTGAATGATATGGAACATCTTTGGTCATTGCTTAGCAATTGCAAGAAAACAAGAGAAAAAGCTTCTGCTACTA
GAGTGTATATTGTTCTCGATAATTCTGGATTTGAGCTTGTTACAGATTTAATATTAGCCGACTTCTTGTTGTCCTCTGAACTGGCTACTG
AGGTTCATTTTTATGGAAAAACAATTCCATGGTTTGTTTCTGATACTACTATACATGATTTTAATTGGTTAATTGAACAGGTAAAACACA
GTAATCATAAGTGGATGTCCAAGTGTGGGGCTGACTGGGAAGAGTATATTAAAATGGGTAAATGGGTTTACCACAATCATATATTTTGGA
CTCTGCCTCATGAGTACTGTGCAATGCCTCAGGTTGCACCTGACTTATATGCTGAACTACAGAAGGCACATTTAATTTTATTCAAGGGTG
ATTTGAATTACAGGAAGTTGACAGGTGACAGAAAATGGGAGTTTTCTGTTCCATTTCATCAGGCTCTGAATGGCTTCCATCCTGCACCAC
TCTGTACCATAAGAACATTAAAAGCTGAAATTCAGGTTGGTCTGCAGCCTGGGCAAGGGGAACAGCTCCTGGCCTCTGAGCCCAGCTGGT
GGACCACTGGAAAATATGGAATATTTCAGTACGATGGTCCCCTTTGACTTGATTTAGGAGCTCTCAGTTGCATAGAAAGATCTGGTGAGC
ACCTTTTCATCCCCAGAAAAGGAGCACGTGAATTGAGTCGCCTGGCGGCTCTGTACGCGCTCAGGGAAGCTTAGCTTCTTGGTGCCCATC
TACGTGCACTGGATGATTTTTCTTTTGAACATTTTGCCCCACTACACTGTTTTGGGGATAGCTGGGTTAAGCAAGTTAAAGATATTTACA
TTTATATTGGAATTTTAGCAACTTTTTTTCAGGTTAAATATATAATTTCAAGTGCTTTTAATGAACTTATTTTTAATTGGCTAGGGAGCA
AAAAATAAGTGAGTTCTGCTTTTAGTTAGTTAACCTTGTTCTTTTCTTAAATAGTACACTGCATGGTATTTAATATTCCAGGAAGCATGG
GATTTTATTTTGCTTGATTTTGGGCACATGAAATAATAGCTCTAGGAAAATGCGCATCTTAATGACTCTTTGTAAAGAGAGGCATTTCTT
ACAACTGTGATGTTTGCTTACATAAAAGTTACCTCATAAGTTAATTCTAACTTTTATTCTTGAATTTTATTTCATTTCAATAGCTTGTTT
CATTTGCACGCCTTTGTATTTTGATTGACCTGTAGAATGGATGTTAGGAAACTCAAAATTGAACACAGTGAAACAAATGGTATTTGAAGA
AATGTAATATCTTTTATATTCTATTTATGATATCCATAATCAAATGAGATTATTTTACCACATAAATGTTTTAAATATCAGATTTTTAGT
TTGCAGTTTTAGGAAAATGCTTTAGATAGAAAAGGTTCTTATGCATTGAATTTGGAGTACTACCAACAATGAATGAATTTATTTTTTATA
TTCTTACACATTTTATTGGTCATTGTCACAGATAGTAAATACTAAAAATTTCAGGTCAGTTTGTTTTGAAACTGAAATTGGAAATAAATC

>27537_27537_2_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000338799_C6orf211_chr6_151775683_ENST00000367294_length(amino acids)=578AA_BP=148
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFG
SNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRSFAYLTIKDRIPQILTKVIDTLHRHKSEF
FEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPP
IDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILL
NDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMS
KCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTL

--------------------------------------------------------------
>27537_27537_3_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000406599_C6orf211_chr6_151775683_ENST00000367294_length(transcript)=2962nt_BP=686nt
AGGAGCTGGCGGAGGGCGTTCGTCCTGGGACTGCACTTGCTCCCGTCGGGTCGCCCGGCTTCACCGGACCCGCAGGCTCCCGGGGCAGGG
CCGGGGCCAGAGCTCGCGTGTCGGCGGGACATGCGCTGCGTCGCCTCTAACCTCGGGCTGTGCTCTTTTTCCAGGTGGCCCGCCGGTTTC
TGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATG
GCCCTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTG
TACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTC
TACGGTCAGACCGGCCTCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGC
GTGTCTCCGAGCCCGCTGATGCTACTGCACCCGCCGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCAGGTGCCCTACTACCTG
GAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGATCATTTGCATATCTTACAATTAAAGACAGAATA
CCACAGATCTTAACTAAGGTTATTGATACATTGCATCGACATAAAAGTGAATTTTTTGAGAAACACGGAGAGGAAGGCGTGGAAGCTGAA
AAGAAAGCTATCTCTCTCCTTTCTAAATTACGGAATGAATTGCAAACAGATAAACCATTTATCCCCTTGGTTGAGAAATTTGTTGATACT
GATATATGGAATCAGTACCTAGAATATCAACAGAGTCTTTTAAATGAAAGTGATGGAAAATCAAGATGGTTCTACTCACCGTGGTTGTTG
GTAGAATGTTACATGTATCGAAGAATTCATGAAGCAATTATCCAGAGTCCACCAATCGATTACTTTGATGTATTTAAAGAATCAAAAGAG
CAAAATTTCTATGGGTCACAGGAATCCATCATTGCTTTATGTACTCACCTGCAACAATTGATAAGAACTATTGAAGACCTAGATGAAAAT
CAGCTGAAAGATGAGTTTTTTAAACTTCTGCAGATTTCACTGTGGGGAAATAAGTGTGATCTGTCTCTCTCAGGTGGAGAAAGTAGTTCT
CAGAATACCAATGTACTAAATTCATTGGAAGACCTAAAACCTTTCATTTTATTGAATGATATGGAACATCTTTGGTCATTGCTTAGCAAT
TGCAAGAAAACAAGAGAAAAAGCTTCTGCTACTAGAGTGTATATTGTTCTCGATAATTCTGGATTTGAGCTTGTTACAGATTTAATATTA
GCCGACTTCTTGTTGTCCTCTGAACTGGCTACTGAGGTTCATTTTTATGGAAAAACAATTCCATGGTTTGTTTCTGATACTACTATACAT
GATTTTAATTGGTTAATTGAACAGGTAAAACACAGTAATCATAAGTGGATGTCCAAGTGTGGGGCTGACTGGGAAGAGTATATTAAAATG
GGTAAATGGGTTTACCACAATCATATATTTTGGACTCTGCCTCATGAGTACTGTGCAATGCCTCAGGTTGCACCTGACTTATATGCTGAA
CTACAGAAGGCACATTTAATTTTATTCAAGGGTGATTTGAATTACAGGAAGTTGACAGGTGACAGAAAATGGGAGTTTTCTGTTCCATTT
CATCAGGCTCTGAATGGCTTCCATCCTGCACCACTCTGTACCATAAGAACATTAAAAGCTGAAATTCAGGTTGGTCTGCAGCCTGGGCAA
GGGGAACAGCTCCTGGCCTCTGAGCCCAGCTGGTGGACCACTGGAAAATATGGAATATTTCAGTACGATGGTCCCCTTTGACTTGATTTA
GGAGCTCTCAGTTGCATAGAAAGATCTGGTGAGCACCTTTTCATCCCCAGAAAAGGAGCACGTGAATTGAGTCGCCTGGCGGCTCTGTAC
GCGCTCAGGGAAGCTTAGCTTCTTGGTGCCCATCTACGTGCACTGGATGATTTTTCTTTTGAACATTTTGCCCCACTACACTGTTTTGGG
GATAGCTGGGTTAAGCAAGTTAAAGATATTTACATTTATATTGGAATTTTAGCAACTTTTTTTCAGGTTAAATATATAATTTCAAGTGCT
TTTAATGAACTTATTTTTAATTGGCTAGGGAGCAAAAAATAAGTGAGTTCTGCTTTTAGTTAGTTAACCTTGTTCTTTTCTTAAATAGTA
CACTGCATGGTATTTAATATTCCAGGAAGCATGGGATTTTATTTTGCTTGATTTTGGGCACATGAAATAATAGCTCTAGGAAAATGCGCA
TCTTAATGACTCTTTGTAAAGAGAGGCATTTCTTACAACTGTGATGTTTGCTTACATAAAAGTTACCTCATAAGTTAATTCTAACTTTTA
TTCTTGAATTTTATTTCATTTCAATAGCTTGTTTCATTTGCACGCCTTTGTATTTTGATTGACCTGTAGAATGGATGTTAGGAAACTCAA
AATTGAACACAGTGAAACAAATGGTATTTGAAGAAATGTAATATCTTTTATATTCTATTTATGATATCCATAATCAAATGAGATTATTTT
ACCACATAAATGTTTTAAATATCAGATTTTTAGTTTGCAGTTTTAGGAAAATGCTTTAGATAGAAAAGGTTCTTATGCATTGAATTTGGA
GTACTACCAACAATGAATGAATTTATTTTTTATATTCTTACACATTTTATTGGTCATTGTCACAGATAGTAAATACTAAAAATTTCAGGT

>27537_27537_3_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000406599_C6orf211_chr6_151775683_ENST00000367294_length(amino acids)=578AA_BP=148
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFG
SNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRSFAYLTIKDRIPQILTKVIDTLHRHKSEF
FEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPP
IDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILL
NDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMS
KCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTL

--------------------------------------------------------------
>27537_27537_4_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000440973_C6orf211_chr6_151775683_ENST00000367294_length(transcript)=3098nt_BP=822nt
ATGGTCATAACAGCCTCCTGTCTACCGACTCAGAACGGATTTTACCAAAACTGAAAATGCAGGCTCCATGCTCAGAAGCTCTTTAACAGG
CTCGAAAGGTCCATGCTCCTTTCTCCTGCCCATTCTATAGCATAAGAAGACAGTCTCTGAGTGATAATCTTCTCTTCAAGAAGAAGAAAA
CTAGGAAGGAGTAAGCACAAAGATCTCTTCACATTCTCCGGGACTGCGGTACCAAATATCAGCACAGCACTTCTTGAAAAAGGATGTAGA
TTTTAATCTGAACTTTGAACCATCACTGAGGTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCG
GCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAA
CCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGG
CGCCGCCTACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCCTCCCCTACGGCCCCGGGTCTGAGGCTGC
GGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGCCGCCGCAGCT
GTCGCCTTTCCTGCAGCCCCACGGCCAGCAGGTGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCC
GGCATTCTACAGATCATTTGCATATCTTACAATTAAAGACAGAATACCACAGATCTTAACTAAGGTTATTGATACATTGCATCGACATAA
AAGTGAATTTTTTGAGAAACACGGAGAGGAAGGCGTGGAAGCTGAAAAGAAAGCTATCTCTCTCCTTTCTAAATTACGGAATGAATTGCA
AACAGATAAACCATTTATCCCCTTGGTTGAGAAATTTGTTGATACTGATATATGGAATCAGTACCTAGAATATCAACAGAGTCTTTTAAA
TGAAAGTGATGGAAAATCAAGATGGTTCTACTCACCGTGGTTGTTGGTAGAATGTTACATGTATCGAAGAATTCATGAAGCAATTATCCA
GAGTCCACCAATCGATTACTTTGATGTATTTAAAGAATCAAAAGAGCAAAATTTCTATGGGTCACAGGAATCCATCATTGCTTTATGTAC
TCACCTGCAACAATTGATAAGAACTATTGAAGACCTAGATGAAAATCAGCTGAAAGATGAGTTTTTTAAACTTCTGCAGATTTCACTGTG
GGGAAATAAGTGTGATCTGTCTCTCTCAGGTGGAGAAAGTAGTTCTCAGAATACCAATGTACTAAATTCATTGGAAGACCTAAAACCTTT
CATTTTATTGAATGATATGGAACATCTTTGGTCATTGCTTAGCAATTGCAAGAAAACAAGAGAAAAAGCTTCTGCTACTAGAGTGTATAT
TGTTCTCGATAATTCTGGATTTGAGCTTGTTACAGATTTAATATTAGCCGACTTCTTGTTGTCCTCTGAACTGGCTACTGAGGTTCATTT
TTATGGAAAAACAATTCCATGGTTTGTTTCTGATACTACTATACATGATTTTAATTGGTTAATTGAACAGGTAAAACACAGTAATCATAA
GTGGATGTCCAAGTGTGGGGCTGACTGGGAAGAGTATATTAAAATGGGTAAATGGGTTTACCACAATCATATATTTTGGACTCTGCCTCA
TGAGTACTGTGCAATGCCTCAGGTTGCACCTGACTTATATGCTGAACTACAGAAGGCACATTTAATTTTATTCAAGGGTGATTTGAATTA
CAGGAAGTTGACAGGTGACAGAAAATGGGAGTTTTCTGTTCCATTTCATCAGGCTCTGAATGGCTTCCATCCTGCACCACTCTGTACCAT
AAGAACATTAAAAGCTGAAATTCAGGTTGGTCTGCAGCCTGGGCAAGGGGAACAGCTCCTGGCCTCTGAGCCCAGCTGGTGGACCACTGG
AAAATATGGAATATTTCAGTACGATGGTCCCCTTTGACTTGATTTAGGAGCTCTCAGTTGCATAGAAAGATCTGGTGAGCACCTTTTCAT
CCCCAGAAAAGGAGCACGTGAATTGAGTCGCCTGGCGGCTCTGTACGCGCTCAGGGAAGCTTAGCTTCTTGGTGCCCATCTACGTGCACT
GGATGATTTTTCTTTTGAACATTTTGCCCCACTACACTGTTTTGGGGATAGCTGGGTTAAGCAAGTTAAAGATATTTACATTTATATTGG
AATTTTAGCAACTTTTTTTCAGGTTAAATATATAATTTCAAGTGCTTTTAATGAACTTATTTTTAATTGGCTAGGGAGCAAAAAATAAGT
GAGTTCTGCTTTTAGTTAGTTAACCTTGTTCTTTTCTTAAATAGTACACTGCATGGTATTTAATATTCCAGGAAGCATGGGATTTTATTT
TGCTTGATTTTGGGCACATGAAATAATAGCTCTAGGAAAATGCGCATCTTAATGACTCTTTGTAAAGAGAGGCATTTCTTACAACTGTGA
TGTTTGCTTACATAAAAGTTACCTCATAAGTTAATTCTAACTTTTATTCTTGAATTTTATTTCATTTCAATAGCTTGTTTCATTTGCACG
CCTTTGTATTTTGATTGACCTGTAGAATGGATGTTAGGAAACTCAAAATTGAACACAGTGAAACAAATGGTATTTGAAGAAATGTAATAT
CTTTTATATTCTATTTATGATATCCATAATCAAATGAGATTATTTTACCACATAAATGTTTTAAATATCAGATTTTTAGTTTGCAGTTTT
AGGAAAATGCTTTAGATAGAAAAGGTTCTTATGCATTGAATTTGGAGTACTACCAACAATGAATGAATTTATTTTTTATATTCTTACACA
TTTTATTGGTCATTGTCACAGATAGTAAATACTAAAAATTTCAGGTCAGTTTGTTTTGAAACTGAAATTGGAAATAAATCTGGAAATGTT

>27537_27537_4_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000440973_C6orf211_chr6_151775683_ENST00000367294_length(amino acids)=578AA_BP=148
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFG
SNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRSFAYLTIKDRIPQILTKVIDTLHRHKSEF
FEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPP
IDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILL
NDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMS
KCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTL

--------------------------------------------------------------
>27537_27537_5_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000443427_C6orf211_chr6_151775683_ENST00000367294_length(transcript)=2989nt_BP=713nt
GACAAACAGAGATATATCGGAGTCTGGCACGGGGCACATAAGGCAGCACATTAGAGAAAGCCGGCCCCTGGATCCGTCTTTCGCGTTTAT
TTTAAGCCCAGTCTTCCCTGGGCCACCTTTAGCAGATCCTCGTGCGCCCCCGCCCCCTGGCCGTGAAACTCAGCCTCTATCCAGCAGCGA
CGACAAGTAAAGTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATG
ACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGCAGCTCAAGATC
CCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAAC
GCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCCTCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGC
CTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGCCGCCGCAGCTGTCGCCTTTCCTGCAGCCC
CACGGCCAGCAGGTGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGATCATTT
GCATATCTTACAATTAAAGACAGAATACCACAGATCTTAACTAAGGTTATTGATACATTGCATCGACATAAAAGTGAATTTTTTGAGAAA
CACGGAGAGGAAGGCGTGGAAGCTGAAAAGAAAGCTATCTCTCTCCTTTCTAAATTACGGAATGAATTGCAAACAGATAAACCATTTATC
CCCTTGGTTGAGAAATTTGTTGATACTGATATATGGAATCAGTACCTAGAATATCAACAGAGTCTTTTAAATGAAAGTGATGGAAAATCA
AGATGGTTCTACTCACCGTGGTTGTTGGTAGAATGTTACATGTATCGAAGAATTCATGAAGCAATTATCCAGAGTCCACCAATCGATTAC
TTTGATGTATTTAAAGAATCAAAAGAGCAAAATTTCTATGGGTCACAGGAATCCATCATTGCTTTATGTACTCACCTGCAACAATTGATA
AGAACTATTGAAGACCTAGATGAAAATCAGCTGAAAGATGAGTTTTTTAAACTTCTGCAGATTTCACTGTGGGGAAATAAGTGTGATCTG
TCTCTCTCAGGTGGAGAAAGTAGTTCTCAGAATACCAATGTACTAAATTCATTGGAAGACCTAAAACCTTTCATTTTATTGAATGATATG
GAACATCTTTGGTCATTGCTTAGCAATTGCAAGAAAACAAGAGAAAAAGCTTCTGCTACTAGAGTGTATATTGTTCTCGATAATTCTGGA
TTTGAGCTTGTTACAGATTTAATATTAGCCGACTTCTTGTTGTCCTCTGAACTGGCTACTGAGGTTCATTTTTATGGAAAAACAATTCCA
TGGTTTGTTTCTGATACTACTATACATGATTTTAATTGGTTAATTGAACAGGTAAAACACAGTAATCATAAGTGGATGTCCAAGTGTGGG
GCTGACTGGGAAGAGTATATTAAAATGGGTAAATGGGTTTACCACAATCATATATTTTGGACTCTGCCTCATGAGTACTGTGCAATGCCT
CAGGTTGCACCTGACTTATATGCTGAACTACAGAAGGCACATTTAATTTTATTCAAGGGTGATTTGAATTACAGGAAGTTGACAGGTGAC
AGAAAATGGGAGTTTTCTGTTCCATTTCATCAGGCTCTGAATGGCTTCCATCCTGCACCACTCTGTACCATAAGAACATTAAAAGCTGAA
ATTCAGGTTGGTCTGCAGCCTGGGCAAGGGGAACAGCTCCTGGCCTCTGAGCCCAGCTGGTGGACCACTGGAAAATATGGAATATTTCAG
TACGATGGTCCCCTTTGACTTGATTTAGGAGCTCTCAGTTGCATAGAAAGATCTGGTGAGCACCTTTTCATCCCCAGAAAAGGAGCACGT
GAATTGAGTCGCCTGGCGGCTCTGTACGCGCTCAGGGAAGCTTAGCTTCTTGGTGCCCATCTACGTGCACTGGATGATTTTTCTTTTGAA
CATTTTGCCCCACTACACTGTTTTGGGGATAGCTGGGTTAAGCAAGTTAAAGATATTTACATTTATATTGGAATTTTAGCAACTTTTTTT
CAGGTTAAATATATAATTTCAAGTGCTTTTAATGAACTTATTTTTAATTGGCTAGGGAGCAAAAAATAAGTGAGTTCTGCTTTTAGTTAG
TTAACCTTGTTCTTTTCTTAAATAGTACACTGCATGGTATTTAATATTCCAGGAAGCATGGGATTTTATTTTGCTTGATTTTGGGCACAT
GAAATAATAGCTCTAGGAAAATGCGCATCTTAATGACTCTTTGTAAAGAGAGGCATTTCTTACAACTGTGATGTTTGCTTACATAAAAGT
TACCTCATAAGTTAATTCTAACTTTTATTCTTGAATTTTATTTCATTTCAATAGCTTGTTTCATTTGCACGCCTTTGTATTTTGATTGAC
CTGTAGAATGGATGTTAGGAAACTCAAAATTGAACACAGTGAAACAAATGGTATTTGAAGAAATGTAATATCTTTTATATTCTATTTATG
ATATCCATAATCAAATGAGATTATTTTACCACATAAATGTTTTAAATATCAGATTTTTAGTTTGCAGTTTTAGGAAAATGCTTTAGATAG
AAAAGGTTCTTATGCATTGAATTTGGAGTACTACCAACAATGAATGAATTTATTTTTTATATTCTTACACATTTTATTGGTCATTGTCAC
AGATAGTAAATACTAAAAATTTCAGGTCAGTTTGTTTTGAAACTGAAATTGGAAATAAATCTGGAAATGTTTTGTTGCACTAAAATAATA

>27537_27537_5_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000443427_C6orf211_chr6_151775683_ENST00000367294_length(amino acids)=578AA_BP=148
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFG
SNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRSFAYLTIKDRIPQILTKVIDTLHRHKSEF
FEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPP
IDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILL
NDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMS
KCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTL

--------------------------------------------------------------
>27537_27537_6_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000456483_C6orf211_chr6_151775683_ENST00000367294_length(transcript)=2946nt_BP=670nt
AAACACATCCACACACTCTCTCTGCCTAGTTCACACACTGAGCCACTCGCACATGCGAGCACATTCCTTCCTTCCTTCTCACTCTCTCGG
CCCTTGACTTCTACAAGCCCATGGAACATTTCTGGAAAGACGTTCTTGATCCAGCAGGGTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTG
CGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGA
TCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCA
AGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCC
TCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGC
TGATGCTACTGCACCCGCCGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCAGGTGCCCTACTACCTGGAGAACGAGCCCAGCG
GCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGATCATTTGCATATCTTACAATTAAAGACAGAATACCACAGATCTTAACTA
AGGTTATTGATACATTGCATCGACATAAAAGTGAATTTTTTGAGAAACACGGAGAGGAAGGCGTGGAAGCTGAAAAGAAAGCTATCTCTC
TCCTTTCTAAATTACGGAATGAATTGCAAACAGATAAACCATTTATCCCCTTGGTTGAGAAATTTGTTGATACTGATATATGGAATCAGT
ACCTAGAATATCAACAGAGTCTTTTAAATGAAAGTGATGGAAAATCAAGATGGTTCTACTCACCGTGGTTGTTGGTAGAATGTTACATGT
ATCGAAGAATTCATGAAGCAATTATCCAGAGTCCACCAATCGATTACTTTGATGTATTTAAAGAATCAAAAGAGCAAAATTTCTATGGGT
CACAGGAATCCATCATTGCTTTATGTACTCACCTGCAACAATTGATAAGAACTATTGAAGACCTAGATGAAAATCAGCTGAAAGATGAGT
TTTTTAAACTTCTGCAGATTTCACTGTGGGGAAATAAGTGTGATCTGTCTCTCTCAGGTGGAGAAAGTAGTTCTCAGAATACCAATGTAC
TAAATTCATTGGAAGACCTAAAACCTTTCATTTTATTGAATGATATGGAACATCTTTGGTCATTGCTTAGCAATTGCAAGAAAACAAGAG
AAAAAGCTTCTGCTACTAGAGTGTATATTGTTCTCGATAATTCTGGATTTGAGCTTGTTACAGATTTAATATTAGCCGACTTCTTGTTGT
CCTCTGAACTGGCTACTGAGGTTCATTTTTATGGAAAAACAATTCCATGGTTTGTTTCTGATACTACTATACATGATTTTAATTGGTTAA
TTGAACAGGTAAAACACAGTAATCATAAGTGGATGTCCAAGTGTGGGGCTGACTGGGAAGAGTATATTAAAATGGGTAAATGGGTTTACC
ACAATCATATATTTTGGACTCTGCCTCATGAGTACTGTGCAATGCCTCAGGTTGCACCTGACTTATATGCTGAACTACAGAAGGCACATT
TAATTTTATTCAAGGGTGATTTGAATTACAGGAAGTTGACAGGTGACAGAAAATGGGAGTTTTCTGTTCCATTTCATCAGGCTCTGAATG
GCTTCCATCCTGCACCACTCTGTACCATAAGAACATTAAAAGCTGAAATTCAGGTTGGTCTGCAGCCTGGGCAAGGGGAACAGCTCCTGG
CCTCTGAGCCCAGCTGGTGGACCACTGGAAAATATGGAATATTTCAGTACGATGGTCCCCTTTGACTTGATTTAGGAGCTCTCAGTTGCA
TAGAAAGATCTGGTGAGCACCTTTTCATCCCCAGAAAAGGAGCACGTGAATTGAGTCGCCTGGCGGCTCTGTACGCGCTCAGGGAAGCTT
AGCTTCTTGGTGCCCATCTACGTGCACTGGATGATTTTTCTTTTGAACATTTTGCCCCACTACACTGTTTTGGGGATAGCTGGGTTAAGC
AAGTTAAAGATATTTACATTTATATTGGAATTTTAGCAACTTTTTTTCAGGTTAAATATATAATTTCAAGTGCTTTTAATGAACTTATTT
TTAATTGGCTAGGGAGCAAAAAATAAGTGAGTTCTGCTTTTAGTTAGTTAACCTTGTTCTTTTCTTAAATAGTACACTGCATGGTATTTA
ATATTCCAGGAAGCATGGGATTTTATTTTGCTTGATTTTGGGCACATGAAATAATAGCTCTAGGAAAATGCGCATCTTAATGACTCTTTG
TAAAGAGAGGCATTTCTTACAACTGTGATGTTTGCTTACATAAAAGTTACCTCATAAGTTAATTCTAACTTTTATTCTTGAATTTTATTT
CATTTCAATAGCTTGTTTCATTTGCACGCCTTTGTATTTTGATTGACCTGTAGAATGGATGTTAGGAAACTCAAAATTGAACACAGTGAA
ACAAATGGTATTTGAAGAAATGTAATATCTTTTATATTCTATTTATGATATCCATAATCAAATGAGATTATTTTACCACATAAATGTTTT
AAATATCAGATTTTTAGTTTGCAGTTTTAGGAAAATGCTTTAGATAGAAAAGGTTCTTATGCATTGAATTTGGAGTACTACCAACAATGA
ATGAATTTATTTTTTATATTCTTACACATTTTATTGGTCATTGTCACAGATAGTAAATACTAAAAATTTCAGGTCAGTTTGTTTTGAAAC

>27537_27537_6_ESR1-C6orf211_ESR1_chr6_152129499_ENST00000456483_C6orf211_chr6_151775683_ENST00000367294_length(amino acids)=578AA_BP=148
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFG
SNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRSFAYLTIKDRIPQILTKVIDTLHRHKSEF
FEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPP
IDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILL
NDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMS
KCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTL

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Fusion Gene PPI Analysis for ESR1-C6orf211


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+18262_595150.66666666666666596.0AKAP13
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+29262_595150.66666666666666596.0AKAP13
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+310262_595150.66666666666666596.0AKAP13
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+29262_595150.66666666666666596.0AKAP13
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+28262_595150.66666666666666484.0AKAP13
HgeneESR1chr6:152129499chr6:151775683ENST00000206249+1835_174150.66666666666666596.0DDX5%3B self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000338799+2935_174150.66666666666666596.0DDX5%3B self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000440973+31035_174150.66666666666666596.0DDX5%3B self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000443427+2935_174150.66666666666666596.0DDX5%3B self-association
HgeneESR1chr6:152129499chr6:151775683ENST00000456483+2835_174150.66666666666666484.0DDX5%3B self-association


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ESR1-C6orf211


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ESR1-C6orf211


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource