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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ETHE1-PLAUR (FusionGDB2 ID:27649)

Fusion Gene Summary for ETHE1-PLAUR

check button Fusion gene summary
Fusion gene informationFusion gene name: ETHE1-PLAUR
Fusion gene ID: 27649
HgeneTgene
Gene symbol

ETHE1

PLAUR

Gene ID

23474

5329

Gene nameETHE1 persulfide dioxygenaseplasminogen activator, urokinase receptor
SynonymsHSCO|YF13H12CD87|U-PAR|UPAR|URKR
Cytomap

19q13.31

19q13.31

Type of geneprotein-codingprotein-coding
Descriptionpersulfide dioxygenase ETHE1, mitochondrialethylmalonic encephalopathy 1hepatoma subtracted clone one proteinprotein ETHE1, mitochondrialsulfur dioxygenase ETHE1urokinase plasminogen activator surface receptormonocyte activation antigen Mo3u-plasminogen activator receptor form 2urokinase-type plasminogen activator (uPA) receptor
Modification date2020031320200329
UniProtAcc

O95571

.
Ensembl transtripts involved in fusion geneENST00000292147, ENST00000600651, 
ENST00000221264, ENST00000340093, 
ENST00000601723, ENST00000339082, 
Fusion gene scores* DoF score10 X 7 X 8=5605 X 4 X 5=100
# samples 116
** MAII scorelog2(11/560*10)=-2.34792330342031
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ETHE1 [Title/Abstract] AND PLAUR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointETHE1(44030667)-PLAUR(44159725), # samples:3
Anticipated loss of major functional domain due to fusion event.ETHE1-PLAUR seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ETHE1-PLAUR seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ETHE1-PLAUR seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ETHE1-PLAUR seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneETHE1

GO:0006749

glutathione metabolic process

23144459

HgeneETHE1

GO:0070813

hydrogen sulfide metabolic process

23144459

TgenePLAUR

GO:0043388

positive regulation of DNA binding

22984561


check buttonFusion gene breakpoints across ETHE1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PLAUR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A8NI-01AETHE1chr19

44030667

-PLAURchr19

44159725

-
ChimerDB4ESCATCGA-L5-A8NIETHE1chr19

44030353

-PLAURchr19

44159725

-
ChimerDB4ESCATCGA-L5-A8NIETHE1chr19

44030666

-PLAURchr19

44156523

-
ChimerDB4ESCATCGA-L5-A8NIETHE1chr19

44030666

-PLAURchr19

44159725

-
ChimerDB4ESCATCGA-L5-A8NIETHE1chr19

44030667

-PLAURchr19

44156523

-
ChimerDB4ESCATCGA-L5-A8NIETHE1chr19

44030667

-PLAURchr19

44159725

-


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Fusion Gene ORF analysis for ETHE1-PLAUR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000292147ENST00000221264ETHE1chr19

44030667

-PLAURchr19

44159725

-
5CDS-intronENST00000292147ENST00000221264ETHE1chr19

44030353

-PLAURchr19

44159725

-
5CDS-intronENST00000292147ENST00000221264ETHE1chr19

44030666

-PLAURchr19

44156523

-
5CDS-intronENST00000292147ENST00000221264ETHE1chr19

44030666

-PLAURchr19

44159725

-
5CDS-intronENST00000292147ENST00000221264ETHE1chr19

44030667

-PLAURchr19

44156523

-
5CDS-intronENST00000292147ENST00000340093ETHE1chr19

44030666

-PLAURchr19

44156523

-
5CDS-intronENST00000292147ENST00000340093ETHE1chr19

44030667

-PLAURchr19

44156523

-
5CDS-intronENST00000292147ENST00000601723ETHE1chr19

44030666

-PLAURchr19

44156523

-
5CDS-intronENST00000292147ENST00000601723ETHE1chr19

44030667

-PLAURchr19

44156523

-
5CDS-intronENST00000600651ENST00000221264ETHE1chr19

44030667

-PLAURchr19

44159725

-
5CDS-intronENST00000600651ENST00000221264ETHE1chr19

44030353

-PLAURchr19

44159725

-
5CDS-intronENST00000600651ENST00000221264ETHE1chr19

44030666

-PLAURchr19

44156523

-
5CDS-intronENST00000600651ENST00000221264ETHE1chr19

44030666

-PLAURchr19

44159725

-
5CDS-intronENST00000600651ENST00000221264ETHE1chr19

44030667

-PLAURchr19

44156523

-
5CDS-intronENST00000600651ENST00000340093ETHE1chr19

44030666

-PLAURchr19

44156523

-
5CDS-intronENST00000600651ENST00000340093ETHE1chr19

44030667

-PLAURchr19

44156523

-
5CDS-intronENST00000600651ENST00000601723ETHE1chr19

44030666

-PLAURchr19

44156523

-
5CDS-intronENST00000600651ENST00000601723ETHE1chr19

44030667

-PLAURchr19

44156523

-
Frame-shiftENST00000292147ENST00000339082ETHE1chr19

44030353

-PLAURchr19

44159725

-
Frame-shiftENST00000292147ENST00000340093ETHE1chr19

44030353

-PLAURchr19

44159725

-
Frame-shiftENST00000292147ENST00000601723ETHE1chr19

44030353

-PLAURchr19

44159725

-
Frame-shiftENST00000600651ENST00000339082ETHE1chr19

44030353

-PLAURchr19

44159725

-
Frame-shiftENST00000600651ENST00000340093ETHE1chr19

44030353

-PLAURchr19

44159725

-
Frame-shiftENST00000600651ENST00000601723ETHE1chr19

44030353

-PLAURchr19

44159725

-
In-frameENST00000292147ENST00000339082ETHE1chr19

44030667

-PLAURchr19

44159725

-
In-frameENST00000292147ENST00000339082ETHE1chr19

44030666

-PLAURchr19

44156523

-
In-frameENST00000292147ENST00000339082ETHE1chr19

44030666

-PLAURchr19

44159725

-
In-frameENST00000292147ENST00000339082ETHE1chr19

44030667

-PLAURchr19

44156523

-
In-frameENST00000292147ENST00000340093ETHE1chr19

44030667

-PLAURchr19

44159725

-
In-frameENST00000292147ENST00000340093ETHE1chr19

44030666

-PLAURchr19

44159725

-
In-frameENST00000292147ENST00000601723ETHE1chr19

44030667

-PLAURchr19

44159725

-
In-frameENST00000292147ENST00000601723ETHE1chr19

44030666

-PLAURchr19

44159725

-
In-frameENST00000600651ENST00000339082ETHE1chr19

44030667

-PLAURchr19

44159725

-
In-frameENST00000600651ENST00000339082ETHE1chr19

44030666

-PLAURchr19

44156523

-
In-frameENST00000600651ENST00000339082ETHE1chr19

44030666

-PLAURchr19

44159725

-
In-frameENST00000600651ENST00000339082ETHE1chr19

44030667

-PLAURchr19

44156523

-
In-frameENST00000600651ENST00000340093ETHE1chr19

44030667

-PLAURchr19

44159725

-
In-frameENST00000600651ENST00000340093ETHE1chr19

44030666

-PLAURchr19

44159725

-
In-frameENST00000600651ENST00000601723ETHE1chr19

44030667

-PLAURchr19

44159725

-
In-frameENST00000600651ENST00000601723ETHE1chr19

44030666

-PLAURchr19

44159725

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000292147ETHE1chr1944030667-ENST00000339082PLAURchr1944159725-102929367666199
ENST00000292147ETHE1chr1944030667-ENST00000601723PLAURchr1944159725-99329367681204
ENST00000292147ETHE1chr1944030667-ENST00000340093PLAURchr1944159725-113929367828253
ENST00000600651ETHE1chr1944030667-ENST00000339082PLAURchr1944159725-98625024623199
ENST00000600651ETHE1chr1944030667-ENST00000601723PLAURchr1944159725-95025024638204
ENST00000600651ETHE1chr1944030667-ENST00000340093PLAURchr1944159725-109625024785253
ENST00000292147ETHE1chr1944030666-ENST00000339082PLAURchr1944159725-102929367666199
ENST00000292147ETHE1chr1944030666-ENST00000601723PLAURchr1944159725-99329367681204
ENST00000292147ETHE1chr1944030666-ENST00000340093PLAURchr1944159725-113929367828253
ENST00000600651ETHE1chr1944030666-ENST00000339082PLAURchr1944159725-98625024623199
ENST00000600651ETHE1chr1944030666-ENST00000601723PLAURchr1944159725-95025024638204
ENST00000600651ETHE1chr1944030666-ENST00000340093PLAURchr1944159725-109625024785253
ENST00000292147ETHE1chr1944030666-ENST00000339082PLAURchr1944156523-89429367531154
ENST00000600651ETHE1chr1944030666-ENST00000339082PLAURchr1944156523-85125024488154
ENST00000292147ETHE1chr1944030667-ENST00000339082PLAURchr1944156523-89429367531154
ENST00000600651ETHE1chr1944030667-ENST00000339082PLAURchr1944156523-85125024488154

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000292147ENST00000339082ETHE1chr1944030667-PLAURchr1944159725-0.059958070.94004196
ENST00000292147ENST00000601723ETHE1chr1944030667-PLAURchr1944159725-0.30675920.6932408
ENST00000292147ENST00000340093ETHE1chr1944030667-PLAURchr1944159725-0.121237720.8787623
ENST00000600651ENST00000339082ETHE1chr1944030667-PLAURchr1944159725-0.063714910.9362851
ENST00000600651ENST00000601723ETHE1chr1944030667-PLAURchr1944159725-0.341762570.6582374
ENST00000600651ENST00000340093ETHE1chr1944030667-PLAURchr1944159725-0.119967070.88003296
ENST00000292147ENST00000339082ETHE1chr1944030666-PLAURchr1944159725-0.059958070.94004196
ENST00000292147ENST00000601723ETHE1chr1944030666-PLAURchr1944159725-0.30675920.6932408
ENST00000292147ENST00000340093ETHE1chr1944030666-PLAURchr1944159725-0.121237720.8787623
ENST00000600651ENST00000339082ETHE1chr1944030666-PLAURchr1944159725-0.063714910.9362851
ENST00000600651ENST00000601723ETHE1chr1944030666-PLAURchr1944159725-0.341762570.6582374
ENST00000600651ENST00000340093ETHE1chr1944030666-PLAURchr1944159725-0.119967070.88003296
ENST00000292147ENST00000339082ETHE1chr1944030666-PLAURchr1944156523-0.097724610.90227544
ENST00000600651ENST00000339082ETHE1chr1944030666-PLAURchr1944156523-0.115517150.88448286
ENST00000292147ENST00000339082ETHE1chr1944030667-PLAURchr1944156523-0.097724610.90227544
ENST00000600651ENST00000339082ETHE1chr1944030667-PLAURchr1944156523-0.115517150.88448286

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Fusion Genomic Features for ETHE1-PLAUR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ETHE1-PLAUR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:44030667/chr19:44159725)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ETHE1

O95571

.
FUNCTION: Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897). {ECO:0000269|PubMed:12398897, ECO:0000269|PubMed:14732903, ECO:0000269|PubMed:19136963, ECO:0000269|PubMed:23144459}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePLAURchr19:44030666chr19:44156523ENST0000022126436214_305157291.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030666chr19:44156523ENST0000033908247214_305202282.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030666chr19:44156523ENST0000034009347214_305202336.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030666chr19:44159725ENST0000022126406115_2130291.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030666chr19:44159725ENST0000022126406214_3050291.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030666chr19:44159725ENST000002212640623_1140291.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030666chr19:44159725ENST0000033908237214_305157282.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030666chr19:44159725ENST0000034009337214_305157336.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030667chr19:44156523ENST0000022126436214_305157291.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030667chr19:44156523ENST0000033908247214_305202282.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030667chr19:44156523ENST0000034009347214_305202336.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030667chr19:44159725ENST0000022126406115_2130291.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030667chr19:44159725ENST0000022126406214_3050291.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030667chr19:44159725ENST000002212640623_1140291.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030667chr19:44159725ENST0000033908237214_305157282.0DomainNote=UPAR/Ly6 3
TgenePLAURchr19:44030667chr19:44159725ENST0000034009337214_305157336.0DomainNote=UPAR/Ly6 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePLAURchr19:44030666chr19:44156523ENST0000022126436115_213157291.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030666chr19:44156523ENST000002212643623_114157291.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030666chr19:44156523ENST0000033908247115_213202282.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030666chr19:44156523ENST000003390824723_114202282.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030666chr19:44156523ENST0000034009347115_213202336.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030666chr19:44156523ENST000003400934723_114202336.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030666chr19:44159725ENST0000033908237115_213157282.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030666chr19:44159725ENST000003390823723_114157282.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030666chr19:44159725ENST0000034009337115_213157336.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030666chr19:44159725ENST000003400933723_114157336.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030667chr19:44156523ENST0000022126436115_213157291.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030667chr19:44156523ENST000002212643623_114157291.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030667chr19:44156523ENST0000033908247115_213202282.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030667chr19:44156523ENST000003390824723_114202282.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030667chr19:44156523ENST0000034009347115_213202336.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030667chr19:44156523ENST000003400934723_114202336.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030667chr19:44159725ENST0000033908237115_213157282.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030667chr19:44159725ENST000003390823723_114157282.0DomainNote=UPAR/Ly6 1
TgenePLAURchr19:44030667chr19:44159725ENST0000034009337115_213157336.0DomainNote=UPAR/Ly6 2
TgenePLAURchr19:44030667chr19:44159725ENST000003400933723_114157336.0DomainNote=UPAR/Ly6 1


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Fusion Gene Sequence for ETHE1-PLAUR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27649_27649_1_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44156523_ENST00000339082_length(transcript)=894nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGTCCTGGAGCTTGAAAATCTGCCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCA
TGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCACT
CTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGACCACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCATG
TGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCACCAGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGCAG
ATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTTCCTAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAACAC
ATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGTGGCTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAAGA

>27649_27649_1_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44156523_ENST00000339082_length(amino acids)=154AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVLELENLPQNGRQCY

--------------------------------------------------------------
>27649_27649_2_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44159725_ENST00000339082_length(transcript)=1029nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGCCACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGG
TTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAACACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCC
GCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCC
CATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCACTCTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGACC
ACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCATGTGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCACC
AGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGCAGATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTTCC
TAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAACACATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGTGG
CTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAAGATCTCTTGAGCTCAGGAGTTCAAGATCAGCCTGGGCAACACAGTGA

>27649_27649_2_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44159725_ENST00000339082_length(amino acids)=199AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHERSLWGSWLPC

--------------------------------------------------------------
>27649_27649_3_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44159725_ENST00000340093_length(transcript)=1139nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGCCACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGG
TTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAACACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCC
GCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCC
CATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACCGAAAAACCAAAGCTATATGGTAAGAGGCTGTGCAACCGCCTCAATGTGCCA
ACATGCCCACCTGGGTGACGCCTTCAGCATGAACCACATTGATGTCTCCTGCTGTACTAAAAGTGGCTGTAACCACCCAGACCTGGATGT
CCAGTACCGCAGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCATCTCAGCCTCACCATCACCCTGCTAATGACTGCCAGACTGTGGGGAGG
CACTCTCCTCTGGACCTAAACCTGAAATCCCCCTCTCTGCCCTGGCTGGATCCGGGGGACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCT
ACAGACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCTCAGTTTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGT
GTGAAGCAGAAGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATGGGAGAGCTCTTGTTATTATTAATATTGTTGCCGCTGTTGTGTTGTTG

>27649_27649_3_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44159725_ENST00000340093_length(amino acids)=253AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRG

--------------------------------------------------------------
>27649_27649_4_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44159725_ENST00000601723_length(transcript)=993nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGCCACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGG
TTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAACACCACCAAATGCAACGAGGGCCCAAAACCGAAAAACCAAAGCTATAT
GGTAAGAGGCTGTGCAACCGCCTCAATGTGCCAACATGCCCACCTGGGTGACGCCTTCAGCATGAACCACATTGATGTCTCCTGCTGTAC
TAAAAGTGGCTGTAACCACCCAGACCTGGATGTCCAGTACCGCAGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCATCTCAGCCTCACCAT
CACCCTGCTAATGACTGCCAGACTGTGGGGAGGCACTCTCCTCTGGACCTAAACCTGAAATCCCCCTCTCTGCCCTGGCTGGATCCGGGG
GACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCTACAGACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCTCAGTTTTC
CCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGAAGCAGAAGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATGGGAGAGCTCTTGTT
ATTATTAATATTGTTGCCGCTGTTGTGTTGTTGTTATTAATTAATATTCATATTATTTATTTTATACTTACATAAAGATTTTGTACCAGT

>27649_27649_4_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000292147_PLAUR_chr19_44159725_ENST00000601723_length(amino acids)=204AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPKPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPG

--------------------------------------------------------------
>27649_27649_5_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44156523_ENST00000339082_length(transcript)=851nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGTCCTGGAGCTTGAAAATCTG
CCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGC
CCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCACTCTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGA
CCACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCATGTGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCA
CCAGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGCAGATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTT
CCTAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAACACATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGT
GGCTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAAGATCTCTTGAGCTCAGGAGTTCAAGATCAGCCTGGGCAACACAGT

>27649_27649_5_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44156523_ENST00000339082_length(amino acids)=154AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVLELENLPQNGRQCY

--------------------------------------------------------------
>27649_27649_6_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44159725_ENST00000339082_length(transcript)=986nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGC
CACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGGTTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAAC
ACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACC
CATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCA
CTCTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGACCACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCA
TGTGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCACCAGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGC
AGATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTTCCTAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAAC
ACATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGTGGCTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAA

>27649_27649_6_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44159725_ENST00000339082_length(amino acids)=199AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHERSLWGSWLPC

--------------------------------------------------------------
>27649_27649_7_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44159725_ENST00000340093_length(transcript)=1096nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGC
CACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGGTTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAAC
ACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACC
CATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACCGAAA
AACCAAAGCTATATGGTAAGAGGCTGTGCAACCGCCTCAATGTGCCAACATGCCCACCTGGGTGACGCCTTCAGCATGAACCACATTGAT
GTCTCCTGCTGTACTAAAAGTGGCTGTAACCACCCAGACCTGGATGTCCAGTACCGCAGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCAT
CTCAGCCTCACCATCACCCTGCTAATGACTGCCAGACTGTGGGGAGGCACTCTCCTCTGGACCTAAACCTGAAATCCCCCTCTCTGCCCT
GGCTGGATCCGGGGGACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCTACAGACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCT
GGGCCTCAGTTTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGAAGCAGAAGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATG
GGAGAGCTCTTGTTATTATTAATATTGTTGCCGCTGTTGTGTTGTTGTTATTAATTAATATTCATATTATTTATTTTATACTTACATAAA

>27649_27649_7_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44159725_ENST00000340093_length(amino acids)=253AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRG

--------------------------------------------------------------
>27649_27649_8_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44159725_ENST00000601723_length(transcript)=950nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGC
CACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGGTTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAAC
ACCACCAAATGCAACGAGGGCCCAAAACCGAAAAACCAAAGCTATATGGTAAGAGGCTGTGCAACCGCCTCAATGTGCCAACATGCCCAC
CTGGGTGACGCCTTCAGCATGAACCACATTGATGTCTCCTGCTGTACTAAAAGTGGCTGTAACCACCCAGACCTGGATGTCCAGTACCGC
AGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCATCTCAGCCTCACCATCACCCTGCTAATGACTGCCAGACTGTGGGGAGGCACTCTCCTC
TGGACCTAAACCTGAAATCCCCCTCTCTGCCCTGGCTGGATCCGGGGGACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCTACAGACTTGC
TGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCTCAGTTTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGAAGCAGA
AGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATGGGAGAGCTCTTGTTATTATTAATATTGTTGCCGCTGTTGTGTTGTTGTTATTAATTA

>27649_27649_8_ETHE1-PLAUR_ETHE1_chr19_44030666_ENST00000600651_PLAUR_chr19_44159725_ENST00000601723_length(amino acids)=204AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPKPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPG

--------------------------------------------------------------
>27649_27649_9_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44156523_ENST00000339082_length(transcript)=894nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGTCCTGGAGCTTGAAAATCTGCCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCA
TGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCACT
CTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGACCACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCATG
TGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCACCAGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGCAG
ATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTTCCTAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAACAC
ATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGTGGCTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAAGA

>27649_27649_9_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44156523_ENST00000339082_length(amino acids)=154AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVLELENLPQNGRQCY

--------------------------------------------------------------
>27649_27649_10_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44159725_ENST00000339082_length(transcript)=1029nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGCCACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGG
TTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAACACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCC
GCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCC
CATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCACTCTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGACC
ACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCATGTGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCACC
AGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGCAGATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTTCC
TAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAACACATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGTGG
CTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAAGATCTCTTGAGCTCAGGAGTTCAAGATCAGCCTGGGCAACACAGTGA

>27649_27649_10_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44159725_ENST00000339082_length(amino acids)=199AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHERSLWGSWLPC

--------------------------------------------------------------
>27649_27649_11_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44159725_ENST00000340093_length(transcript)=1139nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGCCACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGG
TTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAACACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCC
GCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCC
CATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACCGAAAAACCAAAGCTATATGGTAAGAGGCTGTGCAACCGCCTCAATGTGCCA
ACATGCCCACCTGGGTGACGCCTTCAGCATGAACCACATTGATGTCTCCTGCTGTACTAAAAGTGGCTGTAACCACCCAGACCTGGATGT
CCAGTACCGCAGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCATCTCAGCCTCACCATCACCCTGCTAATGACTGCCAGACTGTGGGGAGG
CACTCTCCTCTGGACCTAAACCTGAAATCCCCCTCTCTGCCCTGGCTGGATCCGGGGGACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCT
ACAGACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCTCAGTTTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGT
GTGAAGCAGAAGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATGGGAGAGCTCTTGTTATTATTAATATTGTTGCCGCTGTTGTGTTGTTG

>27649_27649_11_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44159725_ENST00000340093_length(amino acids)=253AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRG

--------------------------------------------------------------
>27649_27649_12_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44159725_ENST00000601723_length(transcript)=993nt_BP=293nt
AGTGCCGTAGCGCCCGGCTCCTGCAGGCGCTCGGCCTCCGCTCATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGT
CGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCCATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTA
CCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGACCCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCT
GGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGCCACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGG
TTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAACACCACCAAATGCAACGAGGGCCCAAAACCGAAAAACCAAAGCTATAT
GGTAAGAGGCTGTGCAACCGCCTCAATGTGCCAACATGCCCACCTGGGTGACGCCTTCAGCATGAACCACATTGATGTCTCCTGCTGTAC
TAAAAGTGGCTGTAACCACCCAGACCTGGATGTCCAGTACCGCAGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCATCTCAGCCTCACCAT
CACCCTGCTAATGACTGCCAGACTGTGGGGAGGCACTCTCCTCTGGACCTAAACCTGAAATCCCCCTCTCTGCCCTGGCTGGATCCGGGG
GACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCTACAGACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCTCAGTTTTC
CCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGAAGCAGAAGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATGGGAGAGCTCTTGTT
ATTATTAATATTGTTGCCGCTGTTGTGTTGTTGTTATTAATTAATATTCATATTATTTATTTTATACTTACATAAAGATTTTGTACCAGT

>27649_27649_12_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000292147_PLAUR_chr19_44159725_ENST00000601723_length(amino acids)=204AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPKPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPG

--------------------------------------------------------------
>27649_27649_13_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44156523_ENST00000339082_length(transcript)=851nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGTCCTGGAGCTTGAAAATCTG
CCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGC
CCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCACTCTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGA
CCACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCATGTGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCA
CCAGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGCAGATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTT
CCTAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAACACATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGT
GGCTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAAGATCTCTTGAGCTCAGGAGTTCAAGATCAGCCTGGGCAACACAGT

>27649_27649_13_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44156523_ENST00000339082_length(amino acids)=154AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVLELENLPQNGRQCY

--------------------------------------------------------------
>27649_27649_14_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44159725_ENST00000339082_length(transcript)=986nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGC
CACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGGTTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAAC
ACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACC
CATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACGCTCA
CTCTGGGGAAGCTGGTTGCCATGTAAAAGTACTACTGCCCTGAGACCACCATGCTGTGAGGAAGCCCAAGCTACTCATGTATAAATGCCA
TGTGGAGATAGAGCCCCAGATGTTTCAGCCATCTCAGCCCAGGCACCAGACAAGTGGGTGAAGAAGCCACCTTGGACATGTAGCCCCAGC
AGATGTGATATAGAGAAGAAACAGGAAACTTGGCTATATTAGTTTCCTAGGGCTGCCTGTGATAAATTATTACAAACTTTATAAACTAAC
ACATTGTGTGCCTATATCAAAACATCATGGAAGGACAGGCACAGTGGCTCATGCCTGTAGTCCTAGCACTTTGGGAGGGTGAGAAAGGAA

>27649_27649_14_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44159725_ENST00000339082_length(amino acids)=199AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHERSLWGSWLPC

--------------------------------------------------------------
>27649_27649_15_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44159725_ENST00000340093_length(transcript)=1096nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGC
CACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGGTTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAAC
ACCACCAAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCCGCAGAATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACC
CATGGATGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCCCATGAATCAATGTCTGGTAGCCACCGGCACTCACGAACCGAAA
AACCAAAGCTATATGGTAAGAGGCTGTGCAACCGCCTCAATGTGCCAACATGCCCACCTGGGTGACGCCTTCAGCATGAACCACATTGAT
GTCTCCTGCTGTACTAAAAGTGGCTGTAACCACCCAGACCTGGATGTCCAGTACCGCAGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCAT
CTCAGCCTCACCATCACCCTGCTAATGACTGCCAGACTGTGGGGAGGCACTCTCCTCTGGACCTAAACCTGAAATCCCCCTCTCTGCCCT
GGCTGGATCCGGGGGACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCTACAGACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCT
GGGCCTCAGTTTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGAAGCAGAAGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATG
GGAGAGCTCTTGTTATTATTAATATTGTTGCCGCTGTTGTGTTGTTGTTATTAATTAATATTCATATTATTTATTTTATACTTACATAAA

>27649_27649_15_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44159725_ENST00000340093_length(amino acids)=253AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRG

--------------------------------------------------------------
>27649_27649_16_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44159725_ENST00000601723_length(transcript)=950nt_BP=250nt
ATTCCTGACCCCGCAGTGGGCGCGATGGCGGAGGCTGTACTGAGGGTCGCCCGGCGGCAGCTGAGCCAGCGCGGCGGGTCTGGAGCCCCC
ATCCTCCTGCGGCAGATGTTCGAGCCTGTGAGCTGCACCTTCACGTACCTGCTGGGTGACAGAGAGTCCCGGGAGGCCGTTCTGATCGAC
CCAGTCCTGGAAACAGCGCCTCGGGATGCCCAGCTGATCAAGGAGCTGGGGCTGCGGCTGCTCTATGCTGGGCGTCCAAAGGATGACCGC
CACCTCCGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGGTTTCCACAACAACGACACCTTCCACTTCCTGAAATGCTGCAAC
ACCACCAAATGCAACGAGGGCCCAAAACCGAAAAACCAAAGCTATATGGTAAGAGGCTGTGCAACCGCCTCAATGTGCCAACATGCCCAC
CTGGGTGACGCCTTCAGCATGAACCACATTGATGTCTCCTGCTGTACTAAAAGTGGCTGTAACCACCCAGACCTGGATGTCCAGTACCGC
AGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCATCTCAGCCTCACCATCACCCTGCTAATGACTGCCAGACTGTGGGGAGGCACTCTCCTC
TGGACCTAAACCTGAAATCCCCCTCTCTGCCCTGGCTGGATCCGGGGGACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCTACAGACTTGC
TGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCTCAGTTTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGAAGCAGA
AGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATGGGAGAGCTCTTGTTATTATTAATATTGTTGCCGCTGTTGTGTTGTTGTTATTAATTA

>27649_27649_16_ETHE1-PLAUR_ETHE1_chr19_44030667_ENST00000600651_PLAUR_chr19_44159725_ENST00000601723_length(amino acids)=204AA_BP=75
MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAGRPKDDRHLRGCGYL
PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPKPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ETHE1-PLAUR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ETHE1-PLAUR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ETHE1-PLAUR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource