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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ETV4-TCAP (FusionGDB2 ID:27694)

Fusion Gene Summary for ETV4-TCAP

check button Fusion gene summary
Fusion gene informationFusion gene name: ETV4-TCAP
Fusion gene ID: 27694
HgeneTgene
Gene symbol

ETV4

TCAP

Gene ID

2118

8557

Gene nameETS variant transcription factor 4titin-cap
SynonymsE1A-F|E1AF|PEA3|PEAS3CMD1N|CMH25|LGMD2G|LGMDR7|T-cap|TELE|telethonin
Cytomap

17q21.31

17q12

Type of geneprotein-codingprotein-coding
DescriptionETS translocation variant 4ETS variant 4EWS protein/E1A enhancer binding protein chimeraadenovirus E1A enhancer-binding proteinets variant gene 4 (E1A enhancer-binding protein, E1AF)polyomavirus enhancer activator 3 homologtelethonin19 kDa sarcomeric proteinlimb girdle muscular dystrophy 2G (autosomal recessive)teneurin C-terminal associated peptidetitin cap protein
Modification date2020031320200327
UniProtAcc

P43268

.
Ensembl transtripts involved in fusion geneENST00000319349, ENST00000393664, 
ENST00000538265, ENST00000545089, 
ENST00000545954, ENST00000591713, 
ENST00000586826, 		ENST00000578283, 
ENST00000309889, 
Fusion gene scores* DoF score4 X 4 X 3=486 X 6 X 6=216
# samples 78
** MAII scorelog2(7/48*10)=0.54432051622381
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(8/216*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ETV4 [Title/Abstract] AND TCAP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointETV4(41610042)-TCAP(37821969), # samples:3
Anticipated loss of major functional domain due to fusion event.ETV4-TCAP seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
ETV4-TCAP seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneETV4

GO:0045944

positive regulation of transcription by RNA polymerase II

24983502


check buttonFusion gene breakpoints across ETV4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TCAP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A4OW-01AETV4chr17

41610042

-TCAPchr17

37821969

+
ChimerDB4ESCATCGA-L5-A4OWETV4chr17

41610041

-TCAPchr17

37821968

+
ChimerDB4ESCATCGA-L5-A4OWETV4chr17

41610042

-TCAPchr17

37821969

+


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Fusion Gene ORF analysis for ETV4-TCAP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000319349ENST00000578283ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000319349ENST00000578283ETV4chr17

41610041

-TCAPchr17

37821968

+
Frame-shiftENST00000393664ENST00000578283ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000393664ENST00000578283ETV4chr17

41610041

-TCAPchr17

37821968

+
Frame-shiftENST00000538265ENST00000309889ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000538265ENST00000309889ETV4chr17

41610041

-TCAPchr17

37821968

+
Frame-shiftENST00000538265ENST00000578283ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000538265ENST00000578283ETV4chr17

41610041

-TCAPchr17

37821968

+
Frame-shiftENST00000545089ENST00000578283ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000545089ENST00000578283ETV4chr17

41610041

-TCAPchr17

37821968

+
Frame-shiftENST00000545954ENST00000309889ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000545954ENST00000309889ETV4chr17

41610041

-TCAPchr17

37821968

+
Frame-shiftENST00000545954ENST00000578283ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000545954ENST00000578283ETV4chr17

41610041

-TCAPchr17

37821968

+
Frame-shiftENST00000591713ENST00000578283ETV4chr17

41610042

-TCAPchr17

37821969

+
Frame-shiftENST00000591713ENST00000578283ETV4chr17

41610041

-TCAPchr17

37821968

+
In-frameENST00000319349ENST00000309889ETV4chr17

41610042

-TCAPchr17

37821969

+
In-frameENST00000319349ENST00000309889ETV4chr17

41610041

-TCAPchr17

37821968

+
In-frameENST00000393664ENST00000309889ETV4chr17

41610042

-TCAPchr17

37821969

+
In-frameENST00000393664ENST00000309889ETV4chr17

41610041

-TCAPchr17

37821968

+
In-frameENST00000545089ENST00000309889ETV4chr17

41610042

-TCAPchr17

37821969

+
In-frameENST00000545089ENST00000309889ETV4chr17

41610041

-TCAPchr17

37821968

+
In-frameENST00000591713ENST00000309889ETV4chr17

41610042

-TCAPchr17

37821969

+
In-frameENST00000591713ENST00000309889ETV4chr17

41610041

-TCAPchr17

37821968

+
intron-3CDSENST00000586826ENST00000309889ETV4chr17

41610042

-TCAPchr17

37821969

+
intron-3CDSENST00000586826ENST00000309889ETV4chr17

41610041

-TCAPchr17

37821968

+
intron-3CDSENST00000586826ENST00000578283ETV4chr17

41610042

-TCAPchr17

37821969

+
intron-3CDSENST00000586826ENST00000578283ETV4chr17

41610041

-TCAPchr17

37821968

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000319349ETV4chr1741610042-ENST00000309889TCAPchr1737821969+19501110801201373
ENST00000393664ETV4chr1741610042-ENST00000309889TCAPchr1737821969+170586554956300
ENST00000545089ETV4chr1741610042-ENST00000309889TCAPchr1737821969+158574596836246
ENST00000591713ETV4chr1741610042-ENST00000309889TCAPchr1737821969+174190190992300
ENST00000319349ETV4chr1741610041-ENST00000309889TCAPchr1737821968+19501110801201373
ENST00000393664ETV4chr1741610041-ENST00000309889TCAPchr1737821968+170586554956300
ENST00000545089ETV4chr1741610041-ENST00000309889TCAPchr1737821968+158574596836246
ENST00000591713ETV4chr1741610041-ENST00000309889TCAPchr1737821968+174190190992300

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000319349ENST00000309889ETV4chr1741610042-TCAPchr1737821969+0.0657471640.93425286
ENST00000393664ENST00000309889ETV4chr1741610042-TCAPchr1737821969+0.062708970.93729097
ENST00000545089ENST00000309889ETV4chr1741610042-TCAPchr1737821969+0.0285827350.9714173
ENST00000591713ENST00000309889ETV4chr1741610042-TCAPchr1737821969+0.065294590.9347054
ENST00000319349ENST00000309889ETV4chr1741610041-TCAPchr1737821968+0.0657471640.93425286
ENST00000393664ENST00000309889ETV4chr1741610041-TCAPchr1737821968+0.062708970.93729097
ENST00000545089ENST00000309889ETV4chr1741610041-TCAPchr1737821968+0.0285827350.9714173
ENST00000591713ENST00000309889ETV4chr1741610041-TCAPchr1737821968+0.065294590.9347054

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Fusion Genomic Features for ETV4-TCAP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ETV4chr1741610041-TCAPchr1737821968+4.74E-070.9999995
ETV4chr1741610041-TCAPchr1737821968+4.74E-070.9999995
ETV4chr1741610041-TCAPchr1737821968+4.74E-070.9999995
ETV4chr1741610041-TCAPchr1737821968+4.74E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ETV4-TCAP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:41610042/chr17:37821969)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ETV4

P43268

.
FUNCTION: Transcriptional activator (PubMed:19307308, PubMed:31552090). May play a role in keratinocyte differentiation (PubMed:31552090). {ECO:0000269|PubMed:19307308, ECO:0000269|PubMed:31552090}.; FUNCTION: (Microbial infection) Binds to the enhancer of the adenovirus E1A gene and acts as a transcriptional activator; the core-binding sequence is 5'-[AC]GGA[AT]GT-3'. {ECO:0000269|PubMed:8441666}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneETV4chr17:41610041chr17:37821968ENST00000319349-813148_244270485.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610041chr17:37821968ENST00000319349-81349_75270485.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610041chr17:37821968ENST00000393664-712148_244270485.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610041chr17:37821968ENST00000393664-71249_75270485.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610041chr17:37821968ENST00000538265-71249_75231446.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610041chr17:37821968ENST00000545954-71249_75231446.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610041chr17:37821968ENST00000591713-813148_244270485.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610041chr17:37821968ENST00000591713-81349_75270485.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610042chr17:37821969ENST00000319349-813148_244270485.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610042chr17:37821969ENST00000319349-81349_75270485.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610042chr17:37821969ENST00000393664-712148_244270485.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610042chr17:37821969ENST00000393664-71249_75270485.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610042chr17:37821969ENST00000538265-71249_75231446.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610042chr17:37821969ENST00000545954-71249_75231446.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneETV4chr17:41610042chr17:37821969ENST00000591713-813148_244270485.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610042chr17:37821969ENST00000591713-81349_75270485.0Compositional biasNote=Asp/Glu-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneETV4chr17:41610041chr17:37821968ENST00000538265-712148_244231446.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610041chr17:37821968ENST00000545954-712148_244231446.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610042chr17:37821969ENST00000538265-712148_244231446.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610042chr17:37821969ENST00000545954-712148_244231446.0Compositional biasNote=Gln-rich
HgeneETV4chr17:41610041chr17:37821968ENST00000319349-813341_421270485.0DNA bindingETS
HgeneETV4chr17:41610041chr17:37821968ENST00000393664-712341_421270485.0DNA bindingETS
HgeneETV4chr17:41610041chr17:37821968ENST00000538265-712341_421231446.0DNA bindingETS
HgeneETV4chr17:41610041chr17:37821968ENST00000545954-712341_421231446.0DNA bindingETS
HgeneETV4chr17:41610041chr17:37821968ENST00000591713-813341_421270485.0DNA bindingETS
HgeneETV4chr17:41610042chr17:37821969ENST00000319349-813341_421270485.0DNA bindingETS
HgeneETV4chr17:41610042chr17:37821969ENST00000393664-712341_421270485.0DNA bindingETS
HgeneETV4chr17:41610042chr17:37821969ENST00000538265-712341_421231446.0DNA bindingETS
HgeneETV4chr17:41610042chr17:37821969ENST00000545954-712341_421231446.0DNA bindingETS
HgeneETV4chr17:41610042chr17:37821969ENST00000591713-813341_421270485.0DNA bindingETS


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Fusion Gene Sequence for ETV4-TCAP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27694_27694_1_ETV4-TCAP_ETV4_chr17_41610041_ENST00000319349_TCAP_chr17_37821968_ENST00000309889_length(transcript)=1950nt_BP=1110nt
GAAACAAAGGGAAACGGGGGGCGGTGTGGCGGGGCGGGGGGTGGAGAGCTGAGGCCGAGCGAAGGAAATGCACCAATCAGCTGCTCCCCC
GGGCTCACAACTGTCTGCTGCGCCCGAAAAACAAGTCGGTGCGCTGGGGACCCGGGGCCGGGGCCGCCTTACTCCGGCCTAGCCCCGCGG
CCCTCGGTGCGGGCTCCAGGGCATGCTCGGGACCCCCCGCGGCTCCAGCCCAGACGCCCCGGCCTCAGGTCTCGGCCCCCGCTTGGGGCC
CCGGCCGTGCGGCCGGAGGGAGCGGCCGGATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAGCAAGTGCCCTACACCTTCAGCAGCA
AATCGCCCGGAAATGGGAGCTTGCGCGAAGCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCGGGCTCCCTGCCGCCCCTCGACTCTG
AAGATCTCTTCCAGGATCTAAGTCACTTCCAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGACAGTGATGAGCAGTTTGTTCCTGATT
TCCATTCAGAAAACCTAGCTTTCCACAGCCCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCCCGCACAGACCCGGCCCTGTCCTGCA
GCAGGAAGCCGCCACTCCCCTACCACCATGGCGAGCAGTGCCTTTACTCCAGTGCCTATGACCCCCCCAGACAAATCGCCATCAAGTCCC
CTGCCCCTGGTGCCCTTGGACAGTCGCCCCTACAGCCCTTTCCCCGGGCAGAGCAACGGAATTTCCTGAGATCCTCTGGCACCTCCCAGC
CCCACCCTGGCCATGGGTACCTCGGGGAACATAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGCCACTCCTTCACATCTCAGGGAGGGG
GCCGGGAACCCCTCCCAGCCCCCTACCAACACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAGCAGAGCTTTAAGCAAGAATACCATG
ATCCCCTGTATGAACAGGCGGGCCAGCCAGCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTACCCAGGGGCGGGGGTGGTGATCAAAC
AGGAACAGACGGACTTCGCCTACGACTCAGCTGCTCCCTGCATGAGGAGGACACCCAGAGACATGAGACCTACCACCAGCAGGGGCAGTG
CCAGGTGCTGGTGCAGCGCTCGCCCTGGCTGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGCAGGAGTACCAGCTGCCCTACCAGCG
GGTACTGCCGCTGCCCATCTTCACCCCTGCCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACACCCCCATCCAGCTTCAGGAGCTGCT
GGCGCTGGAGACAGCCCTGGGTGGCCAGTGTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGCAGCTGCCCCCTGTGGTGCCTGTCAG
CAAGCCCGGTGCACTTCGTCGCTCCCTGTCCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAGAGGGACTGTGACTTGGGCTCCGCTG
TGCCCGCCCTGGGCTGGGCCCTTCCTGGCTAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCTTTGTAGTTTGCCCAGAGTTGGGGGC
TAGGGGAGGGGGGAGCCAGAGGCCAGGATGCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCAGAGACAGTGGGCACTAAGGGTGGAG
AGTTGGGGGCCAGCACAGCTGAGGACCCTCAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGGGCAAGAGGTGCCTGGGAGGAGTGGC
CCTGATCCAGGAAAATGTGAGGGGAATCTGGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGGGAGGTGAAAAGGGCAGAGGCAAGGA

>27694_27694_1_ETV4-TCAP_ETV4_chr17_41610041_ENST00000319349_TCAP_chr17_37821968_ENST00000309889_length(amino acids)=373AA_BP=343
MLPRAHNCLLRPKNKSVRWGPGAGAALLRPSPAALGAGSRACSGPPAAPAQTPRPQVSAPAWGPGRAAGGSGRMERRMKAGYLDQQVPYT
FSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPA
LSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPLDICHSFTS
QGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSAAPCMRRTPRDMRPTTS

--------------------------------------------------------------
>27694_27694_2_ETV4-TCAP_ETV4_chr17_41610041_ENST00000393664_TCAP_chr17_37821968_ENST00000309889_length(transcript)=1705nt_BP=865nt
CAGGTCTCGGCCCCCGCTTGGGGCCCCGGCCGTGCGGCCGGAGGGAGCGGCCGGATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAG
CAAGTGCCCTACACCTTCAGCAGCAAATCGCCCGGAAATGGGAGCTTGCGCGAAGCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCG
GGCTCCCTGCCGCCCCTCGACTCTGAAGATCTCTTCCAGGATCTAAGTCACTTCCAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGAC
AGTGATGAGCAGTTTGTTCCTGATTTCCATTCAGAAAACCTAGCTTTCCACAGCCCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCC
CGCACAGACCCGGCCCTGTCCTGCAGCAGGAAGCCGCCACTCCCCTACCACCATGGCGAGCAGTGCCTTTACTCCAGTGCCTATGACCCC
CCCAGACAAATCGCCATCAAGTCCCCTGCCCCTGGTGCCCTTGGACAGTCGCCCCTACAGCCCTTTCCCCGGGCAGAGCAACGGAATTTC
CTGAGATCCTCTGGCACCTCCCAGCCCCACCCTGGCCATGGGTACCTCGGGGAACATAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGC
CACTCCTTCACATCTCAGGGAGGGGGCCGGGAACCCCTCCCAGCCCCCTACCAACACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAG
CAGAGCTTTAAGCAAGAATACCATGATCCCCTGTATGAACAGGCGGGCCAGCCAGCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTAC
CCAGGGGCGGGGGTGGTGATCAAACAGGAACAGACGGACTTCGCCTACGACTCAGCTGCTCCCTGCATGAGGAGGACACCCAGAGACATG
AGACCTACCACCAGCAGGGGCAGTGCCAGGTGCTGGTGCAGCGCTCGCCCTGGCTGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGC
AGGAGTACCAGCTGCCCTACCAGCGGGTACTGCCGCTGCCCATCTTCACCCCTGCCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACA
CCCCCATCCAGCTTCAGGAGCTGCTGGCGCTGGAGACAGCCCTGGGTGGCCAGTGTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGC
AGCTGCCCCCTGTGGTGCCTGTCAGCAAGCCCGGTGCACTTCGTCGCTCCCTGTCCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAG
AGGGACTGTGACTTGGGCTCCGCTGTGCCCGCCCTGGGCTGGGCCCTTCCTGGCTAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCT
TTGTAGTTTGCCCAGAGTTGGGGGCTAGGGGAGGGGGGAGCCAGAGGCCAGGATGCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCA
GAGACAGTGGGCACTAAGGGTGGAGAGTTGGGGGCCAGCACAGCTGAGGACCCTCAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGG
GCAAGAGGTGCCTGGGAGGAGTGGCCCTGATCCAGGAAAATGTGAGGGGAATCTGGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGG

>27694_27694_2_ETV4-TCAP_ETV4_chr17_41610041_ENST00000393664_TCAP_chr17_37821968_ENST00000309889_length(amino acids)=300AA_BP=270
MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHS
PTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDS

--------------------------------------------------------------
>27694_27694_3_ETV4-TCAP_ETV4_chr17_41610041_ENST00000545089_TCAP_chr17_37821968_ENST00000309889_length(transcript)=1585nt_BP=745nt
AGCCCTCCCTGGACGGTGTGCGAACGCAGCCCCCTCCCCCACCAGGTCTCGGCCCCCGCTTGGGGCCCCGGCCGTGCGGCCGGAGGGAGC
GGCCGGATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAGCAAGTGCCCTACACCTTCAGCAGCAAATCGCCCGGAAATGGGAGCTTG
CGCGAAGCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCGGGCTCCCTGCCGCCCCTCGACTCTGAAGATCTCTTCCAGGATCTAAGT
CACTTCCAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGACAGTGATGAGCAGTTTGTTCCTGATTTCCATTCAGAAAACCTAGCTTTC
CACAGCCCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCCCGCACAGACCCGGCCCTGTCCTGCAGCAGGAAGCCGCCACTCCCCTAC
CACCATGGCGAGCAGTGCCTTTACTCCAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGCCACTCCTTCACATCTCAGGGAGGGGGCCGG
GAACCCCTCCCAGCCCCCTACCAACACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAGCAGAGCTTTAAGCAAGAATACCATGATCCC
CTGTATGAACAGGCGGGCCAGCCAGCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTACCCAGGGGCGGGGGTGGTGATCAAACAGGAA
CAGACGGACTTCGCCTACGACTCAGCTGCTCCCTGCATGAGGAGGACACCCAGAGACATGAGACCTACCACCAGCAGGGGCAGTGCCAGG
TGCTGGTGCAGCGCTCGCCCTGGCTGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGCAGGAGTACCAGCTGCCCTACCAGCGGGTAC
TGCCGCTGCCCATCTTCACCCCTGCCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACACCCCCATCCAGCTTCAGGAGCTGCTGGCGC
TGGAGACAGCCCTGGGTGGCCAGTGTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGCAGCTGCCCCCTGTGGTGCCTGTCAGCAAGC
CCGGTGCACTTCGTCGCTCCCTGTCCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAGAGGGACTGTGACTTGGGCTCCGCTGTGCCC
GCCCTGGGCTGGGCCCTTCCTGGCTAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCTTTGTAGTTTGCCCAGAGTTGGGGGCTAGGG
GAGGGGGGAGCCAGAGGCCAGGATGCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCAGAGACAGTGGGCACTAAGGGTGGAGAGTTG
GGGGCCAGCACAGCTGAGGACCCTCAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGGGCAAGAGGTGCCTGGGAGGAGTGGCCCTGA
TCCAGGAAAATGTGAGGGGAATCTGGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGGGAGGTGAAAAGGGCAGAGGCAAGGATGGTG

>27694_27694_3_ETV4-TCAP_ETV4_chr17_41610041_ENST00000545089_TCAP_chr17_37821968_ENST00000309889_length(amino acids)=246AA_BP=216
MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHS
PTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLY

--------------------------------------------------------------
>27694_27694_4_ETV4-TCAP_ETV4_chr17_41610041_ENST00000591713_TCAP_chr17_37821968_ENST00000309889_length(transcript)=1741nt_BP=901nt
GCAGAAAGCAGAAACGGCGAGCCCGGCTCCTGGGAGCAGGTCTCGGCCCCCGCTTGGGGCCCCGGCCGTGCGGCCGGAGGGAGCGGCCGG
ATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAGCAAGTGCCCTACACCTTCAGCAGCAAATCGCCCGGAAATGGGAGCTTGCGCGAA
GCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCGGGCTCCCTGCCGCCCCTCGACTCTGAAGATCTCTTCCAGGATCTAAGTCACTTC
CAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGACAGTGATGAGCAGTTTGTTCCTGATTTCCATTCAGAAAACCTAGCTTTCCACAGC
CCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCCCGCACAGACCCGGCCCTGTCCTGCAGCAGGAAGCCGCCACTCCCCTACCACCAT
GGCGAGCAGTGCCTTTACTCCAGTGCCTATGACCCCCCCAGACAAATCGCCATCAAGTCCCCTGCCCCTGGTGCCCTTGGACAGTCGCCC
CTACAGCCCTTTCCCCGGGCAGAGCAACGGAATTTCCTGAGATCCTCTGGCACCTCCCAGCCCCACCCTGGCCATGGGTACCTCGGGGAA
CATAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGCCACTCCTTCACATCTCAGGGAGGGGGCCGGGAACCCCTCCCAGCCCCCTACCAA
CACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAGCAGAGCTTTAAGCAAGAATACCATGATCCCCTGTATGAACAGGCGGGCCAGCCA
GCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTACCCAGGGGCGGGGGTGGTGATCAAACAGGAACAGACGGACTTCGCCTACGACTCA
GCTGCTCCCTGCATGAGGAGGACACCCAGAGACATGAGACCTACCACCAGCAGGGGCAGTGCCAGGTGCTGGTGCAGCGCTCGCCCTGGC
TGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGCAGGAGTACCAGCTGCCCTACCAGCGGGTACTGCCGCTGCCCATCTTCACCCCTG
CCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACACCCCCATCCAGCTTCAGGAGCTGCTGGCGCTGGAGACAGCCCTGGGTGGCCAGT
GTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGCAGCTGCCCCCTGTGGTGCCTGTCAGCAAGCCCGGTGCACTTCGTCGCTCCCTGT
CCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAGAGGGACTGTGACTTGGGCTCCGCTGTGCCCGCCCTGGGCTGGGCCCTTCCTGGC
TAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCTTTGTAGTTTGCCCAGAGTTGGGGGCTAGGGGAGGGGGGAGCCAGAGGCCAGGAT
GCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCAGAGACAGTGGGCACTAAGGGTGGAGAGTTGGGGGCCAGCACAGCTGAGGACCCT
CAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGGGCAAGAGGTGCCTGGGAGGAGTGGCCCTGATCCAGGAAAATGTGAGGGGAATCT
GGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGGGAGGTGAAAAGGGCAGAGGCAAGGATGGTGGGGCCCCCAGCACCCTCTGTTAGT

>27694_27694_4_ETV4-TCAP_ETV4_chr17_41610041_ENST00000591713_TCAP_chr17_37821968_ENST00000309889_length(amino acids)=300AA_BP=270
MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHS
PTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDS

--------------------------------------------------------------
>27694_27694_5_ETV4-TCAP_ETV4_chr17_41610042_ENST00000319349_TCAP_chr17_37821969_ENST00000309889_length(transcript)=1950nt_BP=1110nt
GAAACAAAGGGAAACGGGGGGCGGTGTGGCGGGGCGGGGGGTGGAGAGCTGAGGCCGAGCGAAGGAAATGCACCAATCAGCTGCTCCCCC
GGGCTCACAACTGTCTGCTGCGCCCGAAAAACAAGTCGGTGCGCTGGGGACCCGGGGCCGGGGCCGCCTTACTCCGGCCTAGCCCCGCGG
CCCTCGGTGCGGGCTCCAGGGCATGCTCGGGACCCCCCGCGGCTCCAGCCCAGACGCCCCGGCCTCAGGTCTCGGCCCCCGCTTGGGGCC
CCGGCCGTGCGGCCGGAGGGAGCGGCCGGATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAGCAAGTGCCCTACACCTTCAGCAGCA
AATCGCCCGGAAATGGGAGCTTGCGCGAAGCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCGGGCTCCCTGCCGCCCCTCGACTCTG
AAGATCTCTTCCAGGATCTAAGTCACTTCCAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGACAGTGATGAGCAGTTTGTTCCTGATT
TCCATTCAGAAAACCTAGCTTTCCACAGCCCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCCCGCACAGACCCGGCCCTGTCCTGCA
GCAGGAAGCCGCCACTCCCCTACCACCATGGCGAGCAGTGCCTTTACTCCAGTGCCTATGACCCCCCCAGACAAATCGCCATCAAGTCCC
CTGCCCCTGGTGCCCTTGGACAGTCGCCCCTACAGCCCTTTCCCCGGGCAGAGCAACGGAATTTCCTGAGATCCTCTGGCACCTCCCAGC
CCCACCCTGGCCATGGGTACCTCGGGGAACATAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGCCACTCCTTCACATCTCAGGGAGGGG
GCCGGGAACCCCTCCCAGCCCCCTACCAACACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAGCAGAGCTTTAAGCAAGAATACCATG
ATCCCCTGTATGAACAGGCGGGCCAGCCAGCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTACCCAGGGGCGGGGGTGGTGATCAAAC
AGGAACAGACGGACTTCGCCTACGACTCAGCTGCTCCCTGCATGAGGAGGACACCCAGAGACATGAGACCTACCACCAGCAGGGGCAGTG
CCAGGTGCTGGTGCAGCGCTCGCCCTGGCTGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGCAGGAGTACCAGCTGCCCTACCAGCG
GGTACTGCCGCTGCCCATCTTCACCCCTGCCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACACCCCCATCCAGCTTCAGGAGCTGCT
GGCGCTGGAGACAGCCCTGGGTGGCCAGTGTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGCAGCTGCCCCCTGTGGTGCCTGTCAG
CAAGCCCGGTGCACTTCGTCGCTCCCTGTCCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAGAGGGACTGTGACTTGGGCTCCGCTG
TGCCCGCCCTGGGCTGGGCCCTTCCTGGCTAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCTTTGTAGTTTGCCCAGAGTTGGGGGC
TAGGGGAGGGGGGAGCCAGAGGCCAGGATGCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCAGAGACAGTGGGCACTAAGGGTGGAG
AGTTGGGGGCCAGCACAGCTGAGGACCCTCAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGGGCAAGAGGTGCCTGGGAGGAGTGGC
CCTGATCCAGGAAAATGTGAGGGGAATCTGGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGGGAGGTGAAAAGGGCAGAGGCAAGGA

>27694_27694_5_ETV4-TCAP_ETV4_chr17_41610042_ENST00000319349_TCAP_chr17_37821969_ENST00000309889_length(amino acids)=373AA_BP=343
MLPRAHNCLLRPKNKSVRWGPGAGAALLRPSPAALGAGSRACSGPPAAPAQTPRPQVSAPAWGPGRAAGGSGRMERRMKAGYLDQQVPYT
FSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPA
LSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPLDICHSFTS
QGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSAAPCMRRTPRDMRPTTS

--------------------------------------------------------------
>27694_27694_6_ETV4-TCAP_ETV4_chr17_41610042_ENST00000393664_TCAP_chr17_37821969_ENST00000309889_length(transcript)=1705nt_BP=865nt
CAGGTCTCGGCCCCCGCTTGGGGCCCCGGCCGTGCGGCCGGAGGGAGCGGCCGGATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAG
CAAGTGCCCTACACCTTCAGCAGCAAATCGCCCGGAAATGGGAGCTTGCGCGAAGCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCG
GGCTCCCTGCCGCCCCTCGACTCTGAAGATCTCTTCCAGGATCTAAGTCACTTCCAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGAC
AGTGATGAGCAGTTTGTTCCTGATTTCCATTCAGAAAACCTAGCTTTCCACAGCCCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCC
CGCACAGACCCGGCCCTGTCCTGCAGCAGGAAGCCGCCACTCCCCTACCACCATGGCGAGCAGTGCCTTTACTCCAGTGCCTATGACCCC
CCCAGACAAATCGCCATCAAGTCCCCTGCCCCTGGTGCCCTTGGACAGTCGCCCCTACAGCCCTTTCCCCGGGCAGAGCAACGGAATTTC
CTGAGATCCTCTGGCACCTCCCAGCCCCACCCTGGCCATGGGTACCTCGGGGAACATAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGC
CACTCCTTCACATCTCAGGGAGGGGGCCGGGAACCCCTCCCAGCCCCCTACCAACACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAG
CAGAGCTTTAAGCAAGAATACCATGATCCCCTGTATGAACAGGCGGGCCAGCCAGCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTAC
CCAGGGGCGGGGGTGGTGATCAAACAGGAACAGACGGACTTCGCCTACGACTCAGCTGCTCCCTGCATGAGGAGGACACCCAGAGACATG
AGACCTACCACCAGCAGGGGCAGTGCCAGGTGCTGGTGCAGCGCTCGCCCTGGCTGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGC
AGGAGTACCAGCTGCCCTACCAGCGGGTACTGCCGCTGCCCATCTTCACCCCTGCCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACA
CCCCCATCCAGCTTCAGGAGCTGCTGGCGCTGGAGACAGCCCTGGGTGGCCAGTGTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGC
AGCTGCCCCCTGTGGTGCCTGTCAGCAAGCCCGGTGCACTTCGTCGCTCCCTGTCCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAG
AGGGACTGTGACTTGGGCTCCGCTGTGCCCGCCCTGGGCTGGGCCCTTCCTGGCTAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCT
TTGTAGTTTGCCCAGAGTTGGGGGCTAGGGGAGGGGGGAGCCAGAGGCCAGGATGCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCA
GAGACAGTGGGCACTAAGGGTGGAGAGTTGGGGGCCAGCACAGCTGAGGACCCTCAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGG
GCAAGAGGTGCCTGGGAGGAGTGGCCCTGATCCAGGAAAATGTGAGGGGAATCTGGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGG

>27694_27694_6_ETV4-TCAP_ETV4_chr17_41610042_ENST00000393664_TCAP_chr17_37821969_ENST00000309889_length(amino acids)=300AA_BP=270
MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHS
PTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDS

--------------------------------------------------------------
>27694_27694_7_ETV4-TCAP_ETV4_chr17_41610042_ENST00000545089_TCAP_chr17_37821969_ENST00000309889_length(transcript)=1585nt_BP=745nt
AGCCCTCCCTGGACGGTGTGCGAACGCAGCCCCCTCCCCCACCAGGTCTCGGCCCCCGCTTGGGGCCCCGGCCGTGCGGCCGGAGGGAGC
GGCCGGATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAGCAAGTGCCCTACACCTTCAGCAGCAAATCGCCCGGAAATGGGAGCTTG
CGCGAAGCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCGGGCTCCCTGCCGCCCCTCGACTCTGAAGATCTCTTCCAGGATCTAAGT
CACTTCCAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGACAGTGATGAGCAGTTTGTTCCTGATTTCCATTCAGAAAACCTAGCTTTC
CACAGCCCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCCCGCACAGACCCGGCCCTGTCCTGCAGCAGGAAGCCGCCACTCCCCTAC
CACCATGGCGAGCAGTGCCTTTACTCCAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGCCACTCCTTCACATCTCAGGGAGGGGGCCGG
GAACCCCTCCCAGCCCCCTACCAACACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAGCAGAGCTTTAAGCAAGAATACCATGATCCC
CTGTATGAACAGGCGGGCCAGCCAGCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTACCCAGGGGCGGGGGTGGTGATCAAACAGGAA
CAGACGGACTTCGCCTACGACTCAGCTGCTCCCTGCATGAGGAGGACACCCAGAGACATGAGACCTACCACCAGCAGGGGCAGTGCCAGG
TGCTGGTGCAGCGCTCGCCCTGGCTGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGCAGGAGTACCAGCTGCCCTACCAGCGGGTAC
TGCCGCTGCCCATCTTCACCCCTGCCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACACCCCCATCCAGCTTCAGGAGCTGCTGGCGC
TGGAGACAGCCCTGGGTGGCCAGTGTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGCAGCTGCCCCCTGTGGTGCCTGTCAGCAAGC
CCGGTGCACTTCGTCGCTCCCTGTCCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAGAGGGACTGTGACTTGGGCTCCGCTGTGCCC
GCCCTGGGCTGGGCCCTTCCTGGCTAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCTTTGTAGTTTGCCCAGAGTTGGGGGCTAGGG
GAGGGGGGAGCCAGAGGCCAGGATGCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCAGAGACAGTGGGCACTAAGGGTGGAGAGTTG
GGGGCCAGCACAGCTGAGGACCCTCAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGGGCAAGAGGTGCCTGGGAGGAGTGGCCCTGA
TCCAGGAAAATGTGAGGGGAATCTGGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGGGAGGTGAAAAGGGCAGAGGCAAGGATGGTG

>27694_27694_7_ETV4-TCAP_ETV4_chr17_41610042_ENST00000545089_TCAP_chr17_37821969_ENST00000309889_length(amino acids)=246AA_BP=216
MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHS
PTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLY

--------------------------------------------------------------
>27694_27694_8_ETV4-TCAP_ETV4_chr17_41610042_ENST00000591713_TCAP_chr17_37821969_ENST00000309889_length(transcript)=1741nt_BP=901nt
GCAGAAAGCAGAAACGGCGAGCCCGGCTCCTGGGAGCAGGTCTCGGCCCCCGCTTGGGGCCCCGGCCGTGCGGCCGGAGGGAGCGGCCGG
ATGGAGCGGAGGATGAAAGCCGGATACTTGGACCAGCAAGTGCCCTACACCTTCAGCAGCAAATCGCCCGGAAATGGGAGCTTGCGCGAA
GCGCTGATCGGCCCGCTGGGGAAGCTCATGGACCCGGGCTCCCTGCCGCCCCTCGACTCTGAAGATCTCTTCCAGGATCTAAGTCACTTC
CAGGAGACGTGGCTCGCTGAAGCTCAGGTACCAGACAGTGATGAGCAGTTTGTTCCTGATTTCCATTCAGAAAACCTAGCTTTCCACAGC
CCCACCACCAGGATCAAGAAGGAGCCCCAGAGTCCCCGCACAGACCCGGCCCTGTCCTGCAGCAGGAAGCCGCCACTCCCCTACCACCAT
GGCGAGCAGTGCCTTTACTCCAGTGCCTATGACCCCCCCAGACAAATCGCCATCAAGTCCCCTGCCCCTGGTGCCCTTGGACAGTCGCCC
CTACAGCCCTTTCCCCGGGCAGAGCAACGGAATTTCCTGAGATCCTCTGGCACCTCCCAGCCCCACCCTGGCCATGGGTACCTCGGGGAA
CATAGCTCCGTCTTCCAGCAGCCCCTGGACATTTGCCACTCCTTCACATCTCAGGGAGGGGGCCGGGAACCCCTCCCAGCCCCCTACCAA
CACCAGCTGTCGGAGCCCTGCCCACCCTATCCCCAGCAGAGCTTTAAGCAAGAATACCATGATCCCCTGTATGAACAGGCGGGCCAGCCA
GCCGTGGACCAGGGTGGGGTCAATGGGCACAGGTACCCAGGGGCGGGGGTGGTGATCAAACAGGAACAGACGGACTTCGCCTACGACTCA
GCTGCTCCCTGCATGAGGAGGACACCCAGAGACATGAGACCTACCACCAGCAGGGGCAGTGCCAGGTGCTGGTGCAGCGCTCGCCCTGGC
TGATGATGCGGATGGGCATCCTCGGCCGTGGGCTGCAGGAGTACCAGCTGCCCTACCAGCGGGTACTGCCGCTGCCCATCTTCACCCCTG
CCAAGATGGGCGCCACCAAGGAGGAGCGTGAGGACACCCCCATCCAGCTTCAGGAGCTGCTGGCGCTGGAGACAGCCCTGGGTGGCCAGT
GTGTGGACCGCCAGGAGGTGGCTGAGATCACAAAGCAGCTGCCCCCTGTGGTGCCTGTCAGCAAGCCCGGTGCACTTCGTCGCTCCCTGT
CCCGCTCCATGTCCCAGGAAGCACAGAGAGGCTGAGAGGGACTGTGACTTGGGCTCCGCTGTGCCCGCCCTGGGCTGGGCCCTTCCTGGC
TAGGACTGTGGAGGGGAGCTGCTGGCCATGGCTGCTTTGTAGTTTGCCCAGAGTTGGGGGCTAGGGGAGGGGGGAGCCAGAGGCCAGGAT
GCCTGAGCCCCCTGAGTTCCCAAAGGGAGGGTGGCAGAGACAGTGGGCACTAAGGGTGGAGAGTTGGGGGCCAGCACAGCTGAGGACCCT
CAGCCCCAGGAGAAGGGACAAAAGGTACTGGTGAGGGCAAGAGGTGCCTGGGAGGAGTGGCCCTGATCCAGGAAAATGTGAGGGGAATCT
GGAACGCTCTAGGCAGAAGAAGCTGGGAGGGAGGGGGAGGTGAAAAGGGCAGAGGCAAGGATGGTGGGGCCCCCAGCACCCTCTGTTAGT

>27694_27694_8_ETV4-TCAP_ETV4_chr17_41610042_ENST00000591713_TCAP_chr17_37821969_ENST00000309889_length(amino acids)=300AA_BP=270
MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHS
PTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ETV4-TCAP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ETV4-TCAP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ETV4-TCAP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource