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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ETV6-ACSL6 (FusionGDB2 ID:27700)

Fusion Gene Summary for ETV6-ACSL6

check button Fusion gene summary
Fusion gene informationFusion gene name: ETV6-ACSL6
Fusion gene ID: 27700
HgeneTgene
Gene symbol

ETV6

ACSL6

Gene ID

2120

23305

Gene nameETS variant transcription factor 6acyl-CoA synthetase long chain family member 6
SynonymsTEL|TEL/ABL|THC5ACS2|FACL6|LACS 6|LACS2|LACS5
Cytomap

12p13.2

5q31.1

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor ETV6ETS translocation variant 6ETS variant 6ETS-related protein Tel1TEL1 oncogeneets variant gene 6 (TEL oncogene)long-chain-fatty-acid--CoA ligase 6arachidonate--CoA ligasefatty-acid-Coenzyme A ligase, long-chain 6long fatty acyl-CoA synthetase 2
Modification date2020031320200313
UniProtAcc

P41212

Q9UKU0

Ensembl transtripts involved in fusion geneENST00000544715, ENST00000396373, 
ENST00000296869, ENST00000379244, 
ENST00000379246, ENST00000379249, 
ENST00000379255, ENST00000379264, 
ENST00000379272, ENST00000543479, 
ENST00000544770, ENST00000379240, 
ENST00000431707, ENST00000477640, 
ENST00000357096, 
Fusion gene scores* DoF score59 X 37 X 25=545756 X 8 X 8=384
# samples 5810
** MAII scorelog2(58/54575*10)=-6.55604351475058
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/384*10)=-1.94110631094643
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ETV6 [Title/Abstract] AND ACSL6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointETV6(11803094)-ACSL6(131308480), # samples:1
ETV6(11803094)-ACSL6(131329946), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneETV6

GO:0000122

negative regulation of transcription by RNA polymerase II

10514502

TgeneACSL6

GO:0001676

long-chain fatty acid metabolic process

24269233


check buttonFusion gene breakpoints across ETV6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ACSL6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4acute myeloid leukemia;chronic myeloid leukemiaAF102845ETV6chr12

11803094

ACSL6chr5

131308480
ChimerKB3..ETV6chr12

11803094

+ACSL6chr5

131329944

-
ChimerKB4..ETV6chr12

11803094

+ACSL6chr5

131329944

-
ChiTaRS5.0N/AAF102845ETV6chr12

11803094

+ACSL6chr5

131329946

-


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Fusion Gene ORF analysis for ETV6-ACSL6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000544715ENST00000296869ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000379244ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000379246ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000379249ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000379255ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000379264ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000379272ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000543479ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-3CDSENST00000544715ENST00000544770ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-5UTRENST00000544715ENST00000296869ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000296869ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000379240ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000379240ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000379244ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000379244ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000379246ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000379246ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000379249ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000379249ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000379255ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000379255ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000379264ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000379264ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000379272ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000379272ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000431707ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000431707ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000477640ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000477640ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000543479ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000543479ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-5UTRENST00000544715ENST00000544770ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-5UTRENST00000544715ENST00000544770ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-intronENST00000544715ENST00000357096ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-intronENST00000544715ENST00000357096ETV6chr12

11803094

+ACSL6chr5

131329944

-
3UTR-intronENST00000544715ENST00000357096ETV6chr12

11803094

+ACSL6chr5

131329946

-
3UTR-intronENST00000544715ENST00000379240ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-intronENST00000544715ENST00000431707ETV6chr12

11803094

ACSL6chr5

131308480

3UTR-intronENST00000544715ENST00000477640ETV6chr12

11803094

ACSL6chr5

131308480

5CDS-5UTRENST00000396373ENST00000296869ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000296869ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000379240ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000379240ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000379244ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000379244ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000379246ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000379246ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000379249ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000379249ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000379255ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000379255ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000379264ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000379264ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000379272ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000379272ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000431707ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000431707ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000477640ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000477640ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000543479ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000543479ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-5UTRENST00000396373ENST00000544770ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-5UTRENST00000396373ENST00000544770ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-intronENST00000396373ENST00000357096ETV6chr12

11803094

ACSL6chr5

131308480

5CDS-intronENST00000396373ENST00000357096ETV6chr12

11803094

+ACSL6chr5

131329944

-
5CDS-intronENST00000396373ENST00000357096ETV6chr12

11803094

+ACSL6chr5

131329946

-
5CDS-intronENST00000396373ENST00000379240ETV6chr12

11803094

ACSL6chr5

131308480

5CDS-intronENST00000396373ENST00000431707ETV6chr12

11803094

ACSL6chr5

131308480

5CDS-intronENST00000396373ENST00000477640ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000296869ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000379244ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000379246ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000379249ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000379255ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000379264ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000379272ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000543479ETV6chr12

11803094

ACSL6chr5

131308480

In-frameENST00000396373ENST00000544770ETV6chr12

11803094

ACSL6chr5

131308480


check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396373ETV6chr1211803094ENST00000379249ACSL6chr51313084801112307358798146
ENST00000396373ETV6chr1211803094ENST00000379264ACSL6chr5131308480546330747095149146
ENST00000396373ETV6chr1211803094ENST00000379272ACSL6chr5131308480383230730363518160
ENST00000396373ETV6chr1211803094ENST00000379255ACSL6chr513130848015383077841224146
ENST00000396373ETV6chr1211803094ENST00000296869ACSL6chr513130848015343077801220146
ENST00000396373ETV6chr1211803094ENST00000379246ACSL6chr513130848015313077771217146
ENST00000396373ETV6chr1211803094ENST00000379244ACSL6chr513130848015293076401215191
ENST00000396373ETV6chr1211803094ENST00000544770ACSL6chr513130848015243077701210146
ENST00000396373ETV6chr1211803094ENST00000543479ACSL6chr51313084801202307448888146

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396373ENST00000379249ETV6chr1211803094ACSL6chr51313084800.0105514090.98944855
ENST00000396373ENST00000379264ETV6chr1211803094ACSL6chr51313084800.0075312390.9924688
ENST00000396373ENST00000379272ETV6chr1211803094ACSL6chr51313084800.0073040120.99269605
ENST00000396373ENST00000379255ETV6chr1211803094ACSL6chr51313084800.0065747710.99342525
ENST00000396373ENST00000296869ETV6chr1211803094ACSL6chr51313084800.0064334890.9935666
ENST00000396373ENST00000379246ETV6chr1211803094ACSL6chr51313084800.0057052960.9942947
ENST00000396373ENST00000379244ETV6chr1211803094ACSL6chr51313084800.0032151370.9967848
ENST00000396373ENST00000544770ETV6chr1211803094ACSL6chr51313084800.0062719140.99372804
ENST00000396373ENST00000543479ETV6chr1211803094ACSL6chr51313084800.0075071310.99249285

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Fusion Genomic Features for ETV6-ACSL6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ETV6-ACSL6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:11803094/chr5:131308480)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ETV6

P41212

ACSL6

Q9UKU0

FUNCTION: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation. {ECO:0000269|PubMed:25581430}.FUNCTION: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490, PubMed:24269233). Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. {ECO:0000269|PubMed:22633490, ECO:0000269|PubMed:24269233}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for ETV6-ACSL6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27700_27700_1_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000296869_length(transcript)=1534nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTC
AAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGA
ATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTT
TATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCAC
TAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAAAAACATAAGATCTGAAGAAAGCCATTTTGGAAGATATGGTG
AGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGG
GCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATA
TTTAAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCAT
GGGGACAGCTTAAAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGC
GATGGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATG
TTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCA
CCACTCCTGGCGACTGGACCTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTG
GGATTTCTCCGGGCAGCTCTAGGGTGCCAGGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTCTTTAATAAGAT

>27700_27700_1_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000296869_length(amino acids)=146AA_BP=
MKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIR

--------------------------------------------------------------
>27700_27700_2_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379244_length(transcript)=1529nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTC
AAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGA
ATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTT
TATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCAC
TAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAAAAAGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTT
AGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCA
GAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAA
ACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGA
CAGCTTAAAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGG
CTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAG
GAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACT
CCTGGCGACTGGACCTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATT

>27700_27700_2_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379244_length(amino acids)=191AA_BP=
MILWWTAKNITNGNVKIKTFSQELCTTKSNILSMFTELLNIKEKDLKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRG
IEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKICVRGPNVFKGYLKDPDRTKEALDSDGWLH

--------------------------------------------------------------
>27700_27700_3_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379246_length(transcript)=1531nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTC
AAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGA
ATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTT
TATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCAC
TAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAAAAACAGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGG
TTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCC
CAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTT
AAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGG
GACAGCTTAAAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGAT
GGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTG
AGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCA
CTCCTGGCGACTGGACCTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGA
TTTCTCCGGGCAGCTCTAGGGTGCCAGGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTCTTTAATAAGATTCA

>27700_27700_3_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379246_length(amino acids)=146AA_BP=
MKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIR

--------------------------------------------------------------
>27700_27700_4_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379249_length(transcript)=1112nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGACCTACCACAGTGCTTAATACAGATTAAGGTGTTCAGTAAATATTGAGATCT
GAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGCCTTTTTGGTAGGCATTGTTGT
GCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGCAGGAACTCT
TAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAG
CCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCC
AGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCGGGCACGTAGGGGCGCCACTT
CCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGGTTTATGAAGGTTATGGCCAA
ACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACCTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGG
AGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGGGTCCGGAGTGGAATCATCAGGAATGATAGTA

>27700_27700_4_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379249_length(amino acids)=146AA_BP=
MKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIR

--------------------------------------------------------------
>27700_27700_5_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379255_length(transcript)=1538nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTC
AAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGA
ATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTT
TATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCAC
TAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAAAAACATAAGTGAGATCTGAAGAAAGCCATTTTGGAAGATAT
GGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTC
CTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCA
TATATTTAAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGT
CCATGGGGACAGCTTAAAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGA
CAGCGATGGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTT
GATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACC
TTCACCACTCCTGGCGACTGGACCTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGT
TCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTCTTTAATA

>27700_27700_5_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379255_length(amino acids)=146AA_BP=
MKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIR

--------------------------------------------------------------
>27700_27700_6_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379264_length(transcript)=5463nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTC
AAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGA
ATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTT
TATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCAC
TAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAAAAACATAAGTGATATATTCTACTTAATTATTTGTGAATCAG
TAACCAGATGCAGCAAATATCTAGGCAATGTGGACTACCTCATTCAGTAACTGATTGTCAAAATCACAATTAAATCAGACTTCAAAAATT
AAAGCTAGGTGTATAGAATCATGCTAAAAGAAAACATGATAACTCATAGTCTACGTAACTTCAGAGTCTTTAAACATGACAATCCACATT
GTCATATGTGAAAATTTTCTCTCTGATTTTTACTTTCATTCATGAAAAATGAAAATTCAGAAATTCTTTTTTTCCTTTTTGTTTTGAGAC
AGGGTCTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTTAATCATGGCTCATTGCAGTCTCCATCTCCTGGGCTCGAGTGATCCTCCTGT
CTCACCTCCCAAGTAGCTGAGACTACAGTACAGGCACATGCCACCACACCTGGCTAATAGAAATTTTTTTTTTAGAGATTTTGCTCAGGC
TGGTCTCAAACTCCTGAGCTCAAGGGATCCTCCCGCCTTGGCCTCCCTAAGTGCTAGGATTACAGGCATGAGCCATTGTTCCCAGCCAAA
TTCAGATATTATTAAAACACATGTCATATTTATATAGTAACTTACAAAGACCTTTCAATACATTTTCTCATTTATTAAGCTCATTAAAGT
ATTCAGGAACTACCTAGAAAAAATATAATGTAAAACTATTCAAGGATAGTGTGTGTATGTTCATGGACTTCTTATTATAATGAATTCTAA
AAGACATCTGTTGACTCTACAATGAATGGATCCTTGAGGAATACTTGGGAGAAGAAACTCAGAGTTATTTCTCAGGGTAGGCAGCAATTA
ATGTACCTACATTCCTTGCTGGGGTCTTCTAGTCTTCCATTCCCAATGTGCCCATGCTATGCCTGGAAACCCTATATGGTTGTAATTCTG
AACAATTTCACTTTTTTTCCAGTAAGAATATCAAGGCAGAAGGTGGGAAGGAGGGGACATTATTTCCAGGGAAAATAGTTTTTCAACAAT
ATAACTTTGATAAACCTCTTTAAAATGCCCCAAGAAAACTTTTTAAGTCCATAGACAAAGAAATACTGCCTAATGGCATAATTACATTCC
TAAAATCTTTAAGCGTGCCGAAGTTTAACCACTAAAACCTCCTTTCTTGCATTATGTATTTAGATGCACCCTGTATTGGGGTGTCAACAA
TTTCTTATAATTAAAGGCCAGATACCATGGACAGCAATTAAGTTCCAAGCTATAGATTGTGCCTCTGAAAAAGGCATGGACCCCAGGAAC
GTGTTTTTCTTCTGTAGAGACAAGACTCTAAAAGCATATCAACAATCCATATGCAATTCATGTGTTAATTTAAAATGTATGTGCTCAGTG
TTTGTAGTCTAGAAGCTCCTTTCCCTTGGAGGAATGCCAAGCAGTTTGCAAAAATAAATGCTGTTAGTTAAAAACCACATAATCACATGG
GCCTACTGAATAAATATGCATCAGTGATTATATACTTATATTTCAGTCTTGTCAAAAGTGAATCACTGTTTCATTTGATGTATTTACCCA
GTCTTTTTATCCAGTTTTTCTTGGGCATATTCTCTCTGAAGACCCACTGTTGCACTTCTAAATTTGACAGTTAAGAAATGAGCTAGTTCT
ATACACACTGATTTTTAAAGGCGTTTCTGAATAAACTAATACTTAAAATGTCCAAAGTCACATCTGTACAGCATTAGATTTTTATATTTA
ATATATATTTGACTAATTAAAAGTGAAAGTTGTTACCTGAACTGGATATTCATACTATTTTAAGGGCAAGTTGCTTACATTTCAATAACA
ACAAAAAAAGAATCTGTTTCCCATTGTCCTCCTACTCAACTAAAATTCATAGTTGGCTTTAAGCCCAAAAGAATTTTGAACAATGTGACA
GAAACAAGTAATGTAAAACTTATTTTGTTTTATTTATACTTTATAATAGTTAGATATAACAGATTATGGACAACTTAATATTTCTTCTTT
TTGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAAGTCAGGAGATCGAGACCATCC
TGGCTAACACAGTGAAACCCCGTCTCTACTAAAAAAATACAAAAAATTAGCCGGGCGTTGTGGCGGGCGCCTGTAGTCCCAGCTACTCGG
GAGGCTGAGGCAGGAGAATGGCATGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGTACTCCAGCCTGGGCAACAGA
ACGAGACTCCGTCTCAAAAAGAAAGAAAAAAAAAAAACAAAAACAAGGTTTCTTCTTTTTGCCACTTAAAATATCTTATATTTCTAGATT
TCCAGGTCTATGTGGAAATCATCACACTTGGGCCAATAAATGGGTTAGTTCAGATGTGCTGAGAAAAGTAAATAGTGTACCCTAAATATC
TTGCATGTACATTTATCTATTTCTCTGTTTAATGCCACTTAATTTTGTAAGAAATGAGAAATGAAACCCTATGTATCAGTGGAAAAATCC
TTCTTGCTTCAGATTTCCCAACTTTATTCTGGAGGAGAAAAAAATCTGTATTTCTCATTAACAGAGATAGAAAAAGGTGATGTACTTACG
ATGGTCACATTCATATTGGGCATTGGATCTATTTAAGCCTAGAAGTATAACAGATAATCAGTTCCTTAAGTGTAAATATGTTCTTAAATG
TTTGGCCTTTTTATCTGTTATTCAAATGTATTAGTAATTCTCATATTTTGCAAACAGATCCTTTTGTGTATATTATAAAATATATACCAA
ATCTGTTTTTCCTTTTGCTGTGGAAGATGTCTTTATATAATATTGAGACTTCCCTTGCAAATGAGAGACGGGACTCTGGTCAGGTATAGT
GTGTAGGCCTAGCCCCATGTATTAGGAACTCATAAACTCAGAAATCCAAGGATTAAACATTTTATGTCTCCTTCATTTATGCAAGTCATG
CTTTCATTCTACATGTAGTTAAAACTACAAGTATGAGAAAAAATAGAACTTTCCATTGGAATTTTTTCCAATCAGGTAATGTTTTAGCAA
CTTGAAATCAGCACTTAATTTGATTGTATTACCTATCAAAGAACCAATAACCTTTCCTTTTTCTGCAGTAAAGAAAATGAAATATCCTTT
ATTTTCCAAATGTATGAAGCACAAATGCAATATAGTTATTTAAAATATAAAATACTTTAAAATGAATGTGAAGAATGGGAAAATATATTT
TTGCATGAAAACAGACTACTTACAAATGTGCTTAATATCTCAGGAAAAAAAGAATGAATAACCGTATATAAAATTGGTAAACTATAAATT
GGCTGTATTTCCTTGCCGGTTTTAATTTTAAGGAAGCATTTACATGAAAAGAAAAAAGGATCCTAGTAGTCTGAATTTCCTCTCAAGTAT
GCTAGAAAATACTTTCTATGAATTTACAATTAACTGCAATAAGAAGTGGGTTAGCATTCAAGTAAGGTCAATACCCCAAATGAGAAACTC
TTCAGTTAGAACACATTAGTGGTTGTAACACAGAGGCAGTAGATAAATATTTGAAATGTGAGCATTTCTAAACTTGGTACCAAATGGAAA
GGGTTTCATGAGGTGACAGTGGCTTTTAAACATTCATTTGACCGATTATTCTAATTTTCCTTGTTAAATCATTGCAACAGTTGCATGGGG
GAGAATGGATATTTTTTGAAGAATTGCTTATTCCACTTTCAATTTTTAAAAATCGAGGGGATTAAAATATTACTTTTTAAATATGCATAA
AAGTATCTTAACTGTAATTACATTTTCAGTTGCTTTGTTATAGTAGCATGCATATTAAATATAAAATGCATTTATGAAAATTTTTGTAAA
AAATAAAAGATTTTTCATTTCTCAAAGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTT
TTGAGCAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATG
CAGATCTCTGCACAAATAAGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAATATGTTGCAC
CCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGATATGTGTGAGAGGAC
CAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTTCACACTGGAGACATCGGAA
AATGGCTGCCGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGG
AGAGGGAGAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACCTCAGGCCAGTC
TTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGG

>27700_27700_6_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379264_length(amino acids)=146AA_BP=
MKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIR

--------------------------------------------------------------
>27700_27700_7_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379272_length(transcript)=3832nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTC
AAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGA
ATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTT
TATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCAC
TAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAAAAACATAAGTGATATATTCTACTTAATTATTTGTGAATCAG
TAACCAGATGCAGCAAATATCTAGGCAATGTGGACTACCTCATTCAGTAACTGATTGTCAAAATCACAATTAAATCAGACTTCAAAAATT
AAAGCTAGGTGTATAGAATCATGCTAAAAGAAAACATGATAACTCATAGTCTACGTAACTTCAGAGTCTTTAAACATGACAATCCACATT
GTCATATGTGAAAATTTTCTCTCTGATTTTTACTTTCATTCATGAAAAATGAAAATTCAGAAATTCTTTTTTTCCTTTTTGTTTTGAGAC
AGGGTCTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTTAATCATGGCTCATTGCAGTCTCCATCTCCTGGGCTCGAGTGATCCTCCTGT
CTCACCTCCCAAGTAGCTGAGACTACAGTACAGGCACATGCCACCACACCTGGCTAATAGAAATTTTTTTTTTAGAGATTTTGCTCAGGC
TGGTCTCAAACTCCTGAGCTCAAGGGATCCTCCCGCCTTGGCCTCCCTAAGTGCTAGGATTACAGGCATGAGCCATTGTTCCCAGCCAAA
TTCAGATATTATTAAAACACATGTCATATTTATATAGTAACTTACAAAGACCTTTCAATACATTTTCTCATTTATTAAGCTCATTAAAGT
ATTCAGGAACTACCTAGAAAAAATATAATGTAAAACTATTCAAGGATAGTGTGTGTATGTTCATGGACTTCTTATTATAATGAATTCTAA
AAGACATCTGTTGACTCTACAATGAATGGATCCTTGAGGAATACTTGGGAGAAGAAACTCAGAGTTATTTCTCAGGGTAGGCAGCAATTA
ATGTACCTACATTCCTTGCTGGGGTCTTCTAGTCTTCCATTCCCAATGTGCCCATGCTATGCCTGGAAACCCTATATGGTTGTAATTCTG
AACAATTTCACTTTTTTTCCAGTAAGAATATCAAGGCAGAAGGTGGGAAGGAGGGGACATTATTTCCAGGGAAAATAGTTTTTCAACAAT
ATAACTTTGATAAACCTCTTTAAAATGCCCCAAGAAAACTTTTTAAGTCCATAGACAAAGAAATACTGCCTAATGGCATAATTACATTCC
TAAAATCTTTAAGCGTGCCGAAGTTTAACCACTAAAACCTCCTTTCTTGCATTATGTATTTAGATGCACCCTGTATTGGGGTGTCAACAA
TTTCTTATAATTAAAGGCCAGATACCATGGACAGCAATTAAGTTCCAAGCTATAGATTGTGCCTCTGAAAAAGGCATGGACCCCAGGAAC
GTGTTTTTCTTCTGTAGAGACAAGACTCTAAAAGCATATCAACAATCCATATGCAATTCATGTGTTAATTTAAAATGTATGTGCTCAGTG
TTTGTAGTCTAGAAGCTCCTTTCCCTTGGAGGAATGCCAAGCAGTTTGCAAAAATAAATGCTGTTAGTTAAAAACCACATAATCACATGG
GCCTACTGAATAAATATGCATCAGTGATTATATACTTATATTTCAGTCTTGTCAAAAGTGAATCACTGTTTCATTTGATGTATTTACCCA
GTCTTTTTATCCAGTTTTTCTTGGGCATATTCTCTCTGAAGACCCACTGTTGCACTTCTAAATTTGACAGTTAAGAAATGAGCTAGTTCT
ATACACACTGATTTTTAAAGGCGTTTCTGAATAAACTAATACTTAAAATGTCCAAAGTCACATCTGTACAGCATTAGATTTTTATATTTA
ATATATATTTGACTAATTAAAAGTGAAAGTTGTTACCTGAACTGGATATTCATACTATTTTAAGGGCAAGTTGCTTACATTTCAATAACA
ACAAAAAAAGAATCTGTTTCCCATTGTCCTCCTACTCAACTAAAATTCATAGTTGGCTTTAAGCCCAAAAGAATTTTGAACAATGTGACA
GAAACAAGTAATGTAAAACTTATTTTGTTTTATTTATACTTTATAATAGTTAGATATAACAGATTATGGACAACTTAATATTTCTTCTTT
TTGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAAGTCAGGAGATCGAGACCATCC
TGGCTAACACAGTGAAACCCCGTCTCTACTAAAAAAATACAAAAAATTAGCCGGGCGTTGTGGCGGGCGCCTGTAGTCCCAGCTACTCGG
GAGGCTGAGGCAGGAGAATGGCATGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGTACTCCAGCCTGGGCAACAGA
ACGAGACTCCGTCTCGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGCC
TTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGC
ACAAATAAGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATT
GAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGATATGTGTGAGAGGACCAAATGTGTTC
AAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCG
GGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGG
TTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACCTCAGGCCAGTCTTGGTGGGTGT
GTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGGGTCCGGAGTGG

>27700_27700_7_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000379272_length(amino acids)=160AA_BP=
MYSSLGNRTRLRLDLKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQG

--------------------------------------------------------------
>27700_27700_8_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000543479_length(transcript)=1202nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAGATCT
GAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGCCTTTTTGGTAGGCATTGTTGT
GCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGCAGGAACTCT
TAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAG
CCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCC
AGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCGGGCACGTAGGGGCGCCACTT
CCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGGTTTATGAAGGTTATGGCCAA
ACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACCTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGG
AGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGGGTCCGGAGTGGAATCATCAGGAATGATAGTA

>27700_27700_8_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000543479_length(amino acids)=146AA_BP=
MKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIR

--------------------------------------------------------------
>27700_27700_9_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000544770_length(transcript)=1524nt_BP=307nt
GCGTCCCGGGTCCCCGCGCCGCGCCGCGACCTGCAGACCCCGCCGCCGCGCTCGGGCCCGTCTCCCACGCCCCCGCCGCCCCGCGCGCCC
AACTCCGCCGGCCGCCCCGCCCCGCCCCGCGCGCTCCAGACCCCCGGGGCGGCTGCCGGGAGAGATGCTGGAAGAAACTTCTTAAATGAC
CGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTG
AGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCT
GACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTC
AAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGA
ATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTT
TATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCAC
TAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAA
AAGAAAGTGGACTCCATTCTTTTGAGCAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGA
GAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTG
CTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCT
TAAAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGC
TTCACACTGGAGACATCGGAAAATGGCTGCCGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACT
GAACTACTGGGCCTGCAAAGGAGAGGGAGAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGG
CGACTGGACCTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTCC

>27700_27700_9_ETV6-ACSL6_ETV6_chr12_11803094_ENST00000396373_ACSL6_chr5_131308480_ENST00000544770_length(amino acids)=146AA_BP=
MKKAILEDMVRLGKESGLHSFEQAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ETV6-ACSL6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ETV6-ACSL6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ETV6-ACSL6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource