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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AGAP1-UBE2F (FusionGDB2 ID:2791)

Fusion Gene Summary for AGAP1-UBE2F

check button Fusion gene summary
Fusion gene informationFusion gene name: AGAP1-UBE2F
Fusion gene ID: 2791
HgeneTgene
Gene symbol

AGAP1

UBE2F

Gene ID

116987

140739

Gene nameArfGAP with GTPase domain, ankyrin repeat and PH domain 1ubiquitin conjugating enzyme E2 F (putative)
SynonymsAGAP-1|CENTG2|GGAP1|cnt-g2NCE2
Cytomap

2q37.2

2q37.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2NEDD8-conjugating enzyme UBE2FNEDD8 carrier protein UBE2FNEDD8 protein ligase UBE2FNEDD8-conjugating enzyme 2RING-type E3 NEDD8 transferase UBE2Fubiquitin-conjugating enzyme E2F (putative)
Modification date2020031320200313
UniProtAcc

Q9UPQ3

.
Ensembl transtripts involved in fusion geneENST00000304032, ENST00000336665, 
ENST00000409457, ENST00000409538, 
ENST00000428334, 		ENST00000272930, 
ENST00000409332, ENST00000409633, 
ENST00000414443, ENST00000409953, 
Fusion gene scores* DoF score49 X 18 X 17=149943 X 5 X 3=45
# samples 484
** MAII scorelog2(48/14994*10)=-4.96520709119934
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/45*10)=-0.169925001442312
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AGAP1 [Title/Abstract] AND UBE2F [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGAP1(236403493)-UBE2F(238881734), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneUBE2F

GO:0045116

protein neddylation

19250909


check buttonFusion gene breakpoints across AGAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UBE2F (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CR-6484-01AAGAP1chr2

236403493

-UBE2Fchr2

238881734

+
ChimerDB4HNSCTCGA-CR-6484-01AAGAP1chr2

236403493

+UBE2Fchr2

238881734

+
ChimerDB4HNSCTCGA-CR-6484AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
ChimerDB4HNSCTCGA-CR-6484AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
ChimerDB4HNSCTCGA-CR-6484AGAP1chr2

236403493

+UBE2Fchr2

238896605

+


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Fusion Gene ORF analysis for AGAP1-UBE2F

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000304032ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000304032ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000304032ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000304032ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000304032ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000304032ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000304032ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000304032ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000336665ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000336665ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000336665ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000336665ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000336665ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000336665ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000336665ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000336665ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000409457ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000409457ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000409457ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000409457ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000409457ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000409457ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-5UTRENST00000409457ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-5UTRENST00000409457ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-intronENST00000304032ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000304032ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-intronENST00000304032ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-intronENST00000304032ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000304032ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000336665ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000336665ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-intronENST00000336665ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-intronENST00000336665ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000336665ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000409457ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000409457ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
5CDS-intronENST00000409457ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
5CDS-intronENST00000409457ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
5CDS-intronENST00000409457ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
In-frameENST00000304032ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
In-frameENST00000304032ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
In-frameENST00000336665ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
In-frameENST00000336665ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
In-frameENST00000409457ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
In-frameENST00000409457ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-3CDSENST00000409538ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-3CDSENST00000409538ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-3CDSENST00000428334ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-3CDSENST00000428334ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-5UTRENST00000409538ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000409538ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-5UTRENST00000409538ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000409538ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-5UTRENST00000409538ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000409538ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-5UTRENST00000409538ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000409538ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-5UTRENST00000428334ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000428334ENST00000272930AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-5UTRENST00000428334ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000428334ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-5UTRENST00000428334ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000428334ENST00000409633AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-5UTRENST00000428334ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-5UTRENST00000428334ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-intronENST00000409538ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-intronENST00000409538ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-intronENST00000409538ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-intronENST00000409538ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-intronENST00000409538ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-intronENST00000428334ENST00000409332AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-intronENST00000428334ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881734

+
intron-intronENST00000428334ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238881733

+
intron-intronENST00000428334ENST00000409953AGAP1chr2

236403493

+UBE2Fchr2

238896605

+
intron-intronENST00000428334ENST00000414443AGAP1chr2

236403493

+UBE2Fchr2

238896605

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336665AGAP1chr2236403493+ENST00000272930UBE2Fchr2238896605+24407434211182253
ENST00000336665AGAP1chr2236403493+ENST00000409633UBE2Fchr2238896605+13277434211119232
ENST00000304032AGAP1chr2236403493+ENST00000272930UBE2Fchr2238896605+24407434211182253
ENST00000304032AGAP1chr2236403493+ENST00000409633UBE2Fchr2238896605+13277434211119232
ENST00000409457AGAP1chr2236403493+ENST00000272930UBE2Fchr2238896605+24587614391200253
ENST00000409457AGAP1chr2236403493+ENST00000409633UBE2Fchr2238896605+13457614391137232

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336665ENST00000272930AGAP1chr2236403493+UBE2Fchr2238896605+0.0013794320.9986206
ENST00000336665ENST00000409633AGAP1chr2236403493+UBE2Fchr2238896605+0.0019580880.99804187
ENST00000304032ENST00000272930AGAP1chr2236403493+UBE2Fchr2238896605+0.0013794320.9986206
ENST00000304032ENST00000409633AGAP1chr2236403493+UBE2Fchr2238896605+0.0019580880.99804187
ENST00000409457ENST00000272930AGAP1chr2236403493+UBE2Fchr2238896605+0.0016664130.99833363
ENST00000409457ENST00000409633AGAP1chr2236403493+UBE2Fchr2238896605+0.0021940410.997806

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Fusion Genomic Features for AGAP1-UBE2F


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AGAP1chr2236403493+UBE2Fchr2238881733+2.39E-121
AGAP1chr2236403493+UBE2Fchr2238881733+2.39E-121
AGAP1chr2236403493+UBE2Fchr2238896604+1.79E-101
AGAP1chr2236403493+UBE2Fchr2238881733+2.39E-121
AGAP1chr2236403493+UBE2Fchr2238881733+2.39E-121
AGAP1chr2236403493+UBE2Fchr2238896604+1.79E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for AGAP1-UBE2F


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:236403493/chr2:238881734)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AGAP1

Q9UPQ3

.
FUNCTION: GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. {ECO:0000269|PubMed:12640130}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUBE2Fchr2:236403493chr2:238896605ENST000004144430832_1850154.0DomainUBC core

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+118346_58854858.0DomainPH
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+118609_72954858.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+117346_58854805.0DomainPH
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+117609_72954805.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+110346_58854406.0DomainPH
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+110609_72954406.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+118122_12654858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+118178_18154858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+11878_8554858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+117122_12654805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+117178_18154805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+11778_8554805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+110122_12654406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+110178_18154406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+11078_8554406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+11866_27654858.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+11766_27654805.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+11066_27654406.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+118768_79754858.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+118801_83054858.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+117768_79754805.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+117801_83054805.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+110768_79754406.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+110801_83054406.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr2:238896605ENST00000304032+118624_64754858.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr2:238896605ENST00000336665+117624_64754805.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr2:238896605ENST00000409457+110624_64754406.0Zinc fingerC4-type
TgeneUBE2Fchr2:236403493chr2:238896605ENST0000027293011032_18539186.0DomainUBC core


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Fusion Gene Sequence for AGAP1-UBE2F


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2791_2791_1_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000304032_UBE2F_chr2_238896605_ENST00000272930_length(transcript)=2440nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGAGGTTGCAGAACTTGAAGCTAATTTACCTTGTACATGTAAAGTGCATTTTCCTGATCCAAACAAGCT
TCATTGTTTTCAGCTAACAGTAACCCCAGATGAGGGTTACTACCAGGGTGGAAAATTTCAGTTTGAAACTGAAGTTCCCGATGCGTACAA
CATGGTGCCTCCCAAAGTGAAATGCCTGACCAAGATCTGGCACCCCAACATCACAGAGACAGGGGAAATATGTCTGAGTTTATTGAGAGA
ACATTCAATTGATGGCACTGGCTGGGCTCCCACAAGAACATTAAAGGATGTCGTTTGGGGATTAAACTCTTTGTTTACTGATCTTTTGAA
TTTTGATGATCCACTGAATATTGAAGCTGCAGAACATCATTTGCGGGACAAGGAGGACTTCCGGAATAAAGTGGATGACTACATCAAACG
TTATGCCAGATGATAAAAGGGGACGATTGCAGGCCCATGGACTGTGTTACAGTTTGTCTCTAACATGAAACAGCAAGAGGTAGCCCCCTC
TCCCGTCCTCATGCTCCCTCTCAGTCCCCTGGATTGCCCCAGTCCTGTGACCATGTTGCCCTGAAGAAGACCATCTTCATGACTGCTCAT
TGTAGATGGAGAATTCAACATAAATACAGCAAGAAAATGTGTTTGGGCTTCTGAAGAGTTGTCTGCTTACCTTAACATGTTTACTTTTTT
GAACTTGTACTGTATAGGCTGTTGGTGAAATTCTTAAGAAGTTGTAATGAACTCAAAATTGAGGCCAGAGCTTGCTTTCCCTTTTCCCAA
ACAAAATTGGTTTTCTGCACAAGCGATGCTAATGATGTGTTCAGTGTAACTCGCAGATTGGCAATAAGATACCCGCTACAAACTGTGATT
GGATGCAAAATCTCTTAGCTTCTTTCACGAATGTTGGCCCTGCCTAGATGTTGTGAAGCCTCCCAGAATGCATAGAGTCATTCACTGTAG
ATCTCTTATTGAAATGCGTATTTTATTTAATGTAAGTATATTTTGGAACAGATTTGTAATTTGTACAATTCAATGCTTTAATTATTTTTT
CTATTCTCATTTAGTTTGTATTTTCATTGTATAGAGCAGACAGAAAGATGTTGGGTCAAGCAACTATTGAAGAGAAATACAAAGAAAATA
TGAAAGGCACATTATTCATTTTGTCCAAATGCAATGAGAATCTCACTCTTAAAAATCAGCTCTTGCTTTCGGGTCCGGATGTGGTGAGCA
CATTTTGGAGCCCTTTGAAGCTAGATTTGGATGATCAAAACAAAAAGGCAGGGAGCCCATTCTAACATGCTGCCCAGAGGAAACTGGCTG
GAGCCTGGACCAGCTGGGGTTGATGCTTTTGCAGTGGTCATGTGATTGTGACCTGGTAGCTACTTATCAGAGAGCCAGACCCTGCTGTCC
TGGGAGACAGGAGCGATGCCTCAGGAATCAGCCCAATGTCTGATGTCACTGAGACTGTACCTGTGGCCTTCTTCTGAGTTTGCTATGGCT
CCAGGCCCTGCCGGTGGGGTGAGCCTCCTAGGCCTTGGAGGACCAGGAGTCAACAGTGGCATATGCCATCCTCGGCCAGGTTAATATACT
GCAGAGGAAAAGCCCTGAAGAGAGGCAAGTGGATTTACTCCAGCATGTAGACATTTGAACCAGTGAAATCAAACACAAAATAAATGTCTG

>2791_2791_1_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000304032_UBE2F_chr2_238896605_ENST00000272930_length(amino acids)=253AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITET

--------------------------------------------------------------
>2791_2791_2_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000304032_UBE2F_chr2_238896605_ENST00000409633_length(transcript)=1327nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGAGGTTGCAGAACTTGAAGCTAATTTACCTTGTACATGTAAAGTGCATTTTCCTGATCCAAACAAGCT
TCATTGTTTTCAGCTAACAGTAACCCCAGATGAGGGTTACTACCAGGGTGGAAAATTTCAGTTTGAAACTGAAGTTCCCGATGCGTACAA
CATGGTGCCTCCCAAAGTGAAATGCCTGACCAAGATCTGGCACCCCAACATCACAGAGACAGGGGAAATATGTCTGAGTTTATTGAGAGA
ACATTCAATTGATGGCACTGGCTGGGCTCCCACAAGAACATTAAAGGATGTCGTTTGGGGATTAAACTCTTTGTTTACTGAGGACTTCCG
GAATAAAGTGGATGACTACATCAAACGTTATGCCAGATGATAAAAGGGGACGATTGCAGGCCCATGGACTGTGTTACAGTTTGTCTCTAA
CATGAAACAGCAAGAGGTAGCCCCCTCTCCCGTCCTCATGCTCCCTCTCAGTCCCCTGGATTGCCCCAGTCCTGTGACCATGTTGCCCTG

>2791_2791_2_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000304032_UBE2F_chr2_238896605_ENST00000409633_length(amino acids)=232AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITET

--------------------------------------------------------------
>2791_2791_3_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000336665_UBE2F_chr2_238896605_ENST00000272930_length(transcript)=2440nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGAGGTTGCAGAACTTGAAGCTAATTTACCTTGTACATGTAAAGTGCATTTTCCTGATCCAAACAAGCT
TCATTGTTTTCAGCTAACAGTAACCCCAGATGAGGGTTACTACCAGGGTGGAAAATTTCAGTTTGAAACTGAAGTTCCCGATGCGTACAA
CATGGTGCCTCCCAAAGTGAAATGCCTGACCAAGATCTGGCACCCCAACATCACAGAGACAGGGGAAATATGTCTGAGTTTATTGAGAGA
ACATTCAATTGATGGCACTGGCTGGGCTCCCACAAGAACATTAAAGGATGTCGTTTGGGGATTAAACTCTTTGTTTACTGATCTTTTGAA
TTTTGATGATCCACTGAATATTGAAGCTGCAGAACATCATTTGCGGGACAAGGAGGACTTCCGGAATAAAGTGGATGACTACATCAAACG
TTATGCCAGATGATAAAAGGGGACGATTGCAGGCCCATGGACTGTGTTACAGTTTGTCTCTAACATGAAACAGCAAGAGGTAGCCCCCTC
TCCCGTCCTCATGCTCCCTCTCAGTCCCCTGGATTGCCCCAGTCCTGTGACCATGTTGCCCTGAAGAAGACCATCTTCATGACTGCTCAT
TGTAGATGGAGAATTCAACATAAATACAGCAAGAAAATGTGTTTGGGCTTCTGAAGAGTTGTCTGCTTACCTTAACATGTTTACTTTTTT
GAACTTGTACTGTATAGGCTGTTGGTGAAATTCTTAAGAAGTTGTAATGAACTCAAAATTGAGGCCAGAGCTTGCTTTCCCTTTTCCCAA
ACAAAATTGGTTTTCTGCACAAGCGATGCTAATGATGTGTTCAGTGTAACTCGCAGATTGGCAATAAGATACCCGCTACAAACTGTGATT
GGATGCAAAATCTCTTAGCTTCTTTCACGAATGTTGGCCCTGCCTAGATGTTGTGAAGCCTCCCAGAATGCATAGAGTCATTCACTGTAG
ATCTCTTATTGAAATGCGTATTTTATTTAATGTAAGTATATTTTGGAACAGATTTGTAATTTGTACAATTCAATGCTTTAATTATTTTTT
CTATTCTCATTTAGTTTGTATTTTCATTGTATAGAGCAGACAGAAAGATGTTGGGTCAAGCAACTATTGAAGAGAAATACAAAGAAAATA
TGAAAGGCACATTATTCATTTTGTCCAAATGCAATGAGAATCTCACTCTTAAAAATCAGCTCTTGCTTTCGGGTCCGGATGTGGTGAGCA
CATTTTGGAGCCCTTTGAAGCTAGATTTGGATGATCAAAACAAAAAGGCAGGGAGCCCATTCTAACATGCTGCCCAGAGGAAACTGGCTG
GAGCCTGGACCAGCTGGGGTTGATGCTTTTGCAGTGGTCATGTGATTGTGACCTGGTAGCTACTTATCAGAGAGCCAGACCCTGCTGTCC
TGGGAGACAGGAGCGATGCCTCAGGAATCAGCCCAATGTCTGATGTCACTGAGACTGTACCTGTGGCCTTCTTCTGAGTTTGCTATGGCT
CCAGGCCCTGCCGGTGGGGTGAGCCTCCTAGGCCTTGGAGGACCAGGAGTCAACAGTGGCATATGCCATCCTCGGCCAGGTTAATATACT
GCAGAGGAAAAGCCCTGAAGAGAGGCAAGTGGATTTACTCCAGCATGTAGACATTTGAACCAGTGAAATCAAACACAAAATAAATGTCTG

>2791_2791_3_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000336665_UBE2F_chr2_238896605_ENST00000272930_length(amino acids)=253AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITET

--------------------------------------------------------------
>2791_2791_4_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000336665_UBE2F_chr2_238896605_ENST00000409633_length(transcript)=1327nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGAGGTTGCAGAACTTGAAGCTAATTTACCTTGTACATGTAAAGTGCATTTTCCTGATCCAAACAAGCT
TCATTGTTTTCAGCTAACAGTAACCCCAGATGAGGGTTACTACCAGGGTGGAAAATTTCAGTTTGAAACTGAAGTTCCCGATGCGTACAA
CATGGTGCCTCCCAAAGTGAAATGCCTGACCAAGATCTGGCACCCCAACATCACAGAGACAGGGGAAATATGTCTGAGTTTATTGAGAGA
ACATTCAATTGATGGCACTGGCTGGGCTCCCACAAGAACATTAAAGGATGTCGTTTGGGGATTAAACTCTTTGTTTACTGAGGACTTCCG
GAATAAAGTGGATGACTACATCAAACGTTATGCCAGATGATAAAAGGGGACGATTGCAGGCCCATGGACTGTGTTACAGTTTGTCTCTAA
CATGAAACAGCAAGAGGTAGCCCCCTCTCCCGTCCTCATGCTCCCTCTCAGTCCCCTGGATTGCCCCAGTCCTGTGACCATGTTGCCCTG

>2791_2791_4_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000336665_UBE2F_chr2_238896605_ENST00000409633_length(amino acids)=232AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITET

--------------------------------------------------------------
>2791_2791_5_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000409457_UBE2F_chr2_238896605_ENST00000272930_length(transcript)=2458nt_BP=761nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGAGGTTGCAGAACTTGAAGCTAATTTACCTTGTACATGTAAAGTGCATTT
TCCTGATCCAAACAAGCTTCATTGTTTTCAGCTAACAGTAACCCCAGATGAGGGTTACTACCAGGGTGGAAAATTTCAGTTTGAAACTGA
AGTTCCCGATGCGTACAACATGGTGCCTCCCAAAGTGAAATGCCTGACCAAGATCTGGCACCCCAACATCACAGAGACAGGGGAAATATG
TCTGAGTTTATTGAGAGAACATTCAATTGATGGCACTGGCTGGGCTCCCACAAGAACATTAAAGGATGTCGTTTGGGGATTAAACTCTTT
GTTTACTGATCTTTTGAATTTTGATGATCCACTGAATATTGAAGCTGCAGAACATCATTTGCGGGACAAGGAGGACTTCCGGAATAAAGT
GGATGACTACATCAAACGTTATGCCAGATGATAAAAGGGGACGATTGCAGGCCCATGGACTGTGTTACAGTTTGTCTCTAACATGAAACA
GCAAGAGGTAGCCCCCTCTCCCGTCCTCATGCTCCCTCTCAGTCCCCTGGATTGCCCCAGTCCTGTGACCATGTTGCCCTGAAGAAGACC
ATCTTCATGACTGCTCATTGTAGATGGAGAATTCAACATAAATACAGCAAGAAAATGTGTTTGGGCTTCTGAAGAGTTGTCTGCTTACCT
TAACATGTTTACTTTTTTGAACTTGTACTGTATAGGCTGTTGGTGAAATTCTTAAGAAGTTGTAATGAACTCAAAATTGAGGCCAGAGCT
TGCTTTCCCTTTTCCCAAACAAAATTGGTTTTCTGCACAAGCGATGCTAATGATGTGTTCAGTGTAACTCGCAGATTGGCAATAAGATAC
CCGCTACAAACTGTGATTGGATGCAAAATCTCTTAGCTTCTTTCACGAATGTTGGCCCTGCCTAGATGTTGTGAAGCCTCCCAGAATGCA
TAGAGTCATTCACTGTAGATCTCTTATTGAAATGCGTATTTTATTTAATGTAAGTATATTTTGGAACAGATTTGTAATTTGTACAATTCA
ATGCTTTAATTATTTTTTCTATTCTCATTTAGTTTGTATTTTCATTGTATAGAGCAGACAGAAAGATGTTGGGTCAAGCAACTATTGAAG
AGAAATACAAAGAAAATATGAAAGGCACATTATTCATTTTGTCCAAATGCAATGAGAATCTCACTCTTAAAAATCAGCTCTTGCTTTCGG
GTCCGGATGTGGTGAGCACATTTTGGAGCCCTTTGAAGCTAGATTTGGATGATCAAAACAAAAAGGCAGGGAGCCCATTCTAACATGCTG
CCCAGAGGAAACTGGCTGGAGCCTGGACCAGCTGGGGTTGATGCTTTTGCAGTGGTCATGTGATTGTGACCTGGTAGCTACTTATCAGAG
AGCCAGACCCTGCTGTCCTGGGAGACAGGAGCGATGCCTCAGGAATCAGCCCAATGTCTGATGTCACTGAGACTGTACCTGTGGCCTTCT
TCTGAGTTTGCTATGGCTCCAGGCCCTGCCGGTGGGGTGAGCCTCCTAGGCCTTGGAGGACCAGGAGTCAACAGTGGCATATGCCATCCT
CGGCCAGGTTAATATACTGCAGAGGAAAAGCCCTGAAGAGAGGCAAGTGGATTTACTCCAGCATGTAGACATTTGAACCAGTGAAATCAA

>2791_2791_5_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000409457_UBE2F_chr2_238896605_ENST00000272930_length(amino acids)=253AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITET

--------------------------------------------------------------
>2791_2791_6_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000409457_UBE2F_chr2_238896605_ENST00000409633_length(transcript)=1345nt_BP=761nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGAGGTTGCAGAACTTGAAGCTAATTTACCTTGTACATGTAAAGTGCATTT
TCCTGATCCAAACAAGCTTCATTGTTTTCAGCTAACAGTAACCCCAGATGAGGGTTACTACCAGGGTGGAAAATTTCAGTTTGAAACTGA
AGTTCCCGATGCGTACAACATGGTGCCTCCCAAAGTGAAATGCCTGACCAAGATCTGGCACCCCAACATCACAGAGACAGGGGAAATATG
TCTGAGTTTATTGAGAGAACATTCAATTGATGGCACTGGCTGGGCTCCCACAAGAACATTAAAGGATGTCGTTTGGGGATTAAACTCTTT
GTTTACTGAGGACTTCCGGAATAAAGTGGATGACTACATCAAACGTTATGCCAGATGATAAAAGGGGACGATTGCAGGCCCATGGACTGT
GTTACAGTTTGTCTCTAACATGAAACAGCAAGAGGTAGCCCCCTCTCCCGTCCTCATGCTCCCTCTCAGTCCCCTGGATTGCCCCAGTCC

>2791_2791_6_AGAP1-UBE2F_AGAP1_chr2_236403493_ENST00000409457_UBE2F_chr2_238896605_ENST00000409633_length(amino acids)=232AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITET

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AGAP1-UBE2F


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneUBE2Fchr2:236403493chr2:238896605ENST00000414443081_290154.0UBA3


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneUBE2Fchr2:236403493chr2:238896605ENST000002729301101_2939.333333333333336186.0UBA3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AGAP1-UBE2F


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AGAP1-UBE2F


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource