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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAF1-EIF5 (FusionGDB2 ID:28231)

Fusion Gene Summary for FAF1-EIF5

check button Fusion gene summary
Fusion gene informationFusion gene name: FAF1-EIF5
Fusion gene ID: 28231
HgeneTgene
Gene symbol

FAF1

EIF5

Gene ID

11124

1983

Gene nameFas associated factor 1eukaryotic translation initiation factor 5
SynonymsCGI-03|HFAF1s|UBXD12|UBXN3A|hFAF1EIF-5|EIF-5A
Cytomap

1p32.3

14q32.32

Type of geneprotein-codingprotein-coding
DescriptionFAS-associated factor 1Fas (TNFRSF6) associated factor 1TNFRSF6-associated factor 1UBX domain protein 3AUBX domain-containing protein 12UBX domain-containing protein 3Aeukaryotic translation initiation factor 5
Modification date2020031320200313
UniProtAcc

Q9UNN5

O60841

Ensembl transtripts involved in fusion geneENST00000371778, ENST00000396153, 
ENST00000545823, ENST00000472808, 
ENST00000392715, ENST00000560200, 
ENST00000216554, ENST00000558506, 
Fusion gene scores* DoF score23 X 21 X 9=434711 X 10 X 6=660
# samples 3113
** MAII scorelog2(31/4347*10)=-3.80967997500385
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/660*10)=-2.34395440121736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAF1 [Title/Abstract] AND EIF5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAF1(51048290)-EIF5(103805509), # samples:1
Anticipated loss of major functional domain due to fusion event.FAF1-EIF5 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
FAF1-EIF5 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
FAF1-EIF5 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFAF1

GO:0010942

positive regulation of cell death

15596450

TgeneEIF5

GO:0006446

regulation of translational initiation

22156057


check buttonFusion gene breakpoints across FAF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-14-1034-01AFAF1chr1

51048290

-EIF5chr14

103805509

+


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Fusion Gene ORF analysis for FAF1-EIF5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000371778ENST00000392715FAF1chr1

51048290

-EIF5chr14

103805509

+
5CDS-intronENST00000371778ENST00000560200FAF1chr1

51048290

-EIF5chr14

103805509

+
5CDS-intronENST00000396153ENST00000392715FAF1chr1

51048290

-EIF5chr14

103805509

+
5CDS-intronENST00000396153ENST00000560200FAF1chr1

51048290

-EIF5chr14

103805509

+
5CDS-intronENST00000545823ENST00000392715FAF1chr1

51048290

-EIF5chr14

103805509

+
5CDS-intronENST00000545823ENST00000560200FAF1chr1

51048290

-EIF5chr14

103805509

+
5UTR-3CDSENST00000472808ENST00000216554FAF1chr1

51048290

-EIF5chr14

103805509

+
5UTR-3CDSENST00000472808ENST00000558506FAF1chr1

51048290

-EIF5chr14

103805509

+
5UTR-intronENST00000472808ENST00000392715FAF1chr1

51048290

-EIF5chr14

103805509

+
5UTR-intronENST00000472808ENST00000560200FAF1chr1

51048290

-EIF5chr14

103805509

+
Frame-shiftENST00000371778ENST00000216554FAF1chr1

51048290

-EIF5chr14

103805509

+
Frame-shiftENST00000371778ENST00000558506FAF1chr1

51048290

-EIF5chr14

103805509

+
In-frameENST00000396153ENST00000216554FAF1chr1

51048290

-EIF5chr14

103805509

+
In-frameENST00000396153ENST00000558506FAF1chr1

51048290

-EIF5chr14

103805509

+
In-frameENST00000545823ENST00000216554FAF1chr1

51048290

-EIF5chr14

103805509

+
In-frameENST00000545823ENST00000558506FAF1chr1

51048290

-EIF5chr14

103805509

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396153FAF1chr151048290-ENST00000216554EIF5chr14103805509+609015651402116658
ENST00000396153FAF1chr151048290-ENST00000558506EIF5chr14103805509+429315651402116658
ENST00000545823FAF1chr151048290-ENST00000216554EIF5chr14103805509+50625371501088312
ENST00000545823FAF1chr151048290-ENST00000558506EIF5chr14103805509+32655371501088312

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396153ENST00000216554FAF1chr151048290-EIF5chr14103805509+0.0001254040.9998746
ENST00000396153ENST00000558506FAF1chr151048290-EIF5chr14103805509+0.0001481740.9998518
ENST00000545823ENST00000216554FAF1chr151048290-EIF5chr14103805509+8.72E-050.99991274
ENST00000545823ENST00000558506FAF1chr151048290-EIF5chr14103805509+8.37E-050.9999163

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Fusion Genomic Features for FAF1-EIF5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FAF1chr151048289-EIF5chr14103805508+0.001884420.99811554
FAF1chr151048289-EIF5chr14103805508+0.001884420.99811554

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FAF1-EIF5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:51048290/chr14:103805509)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FAF1

Q9UNN5

EIF5

O60841

FUNCTION: Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564). Potentiates but cannot initiate FAS-induced apoptosis (By similarity). {ECO:0000250|UniProtKB:P54731, ECO:0000269|PubMed:19722279, ECO:0000269|PubMed:26842564}.FUNCTION: Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes. {ECO:0000250|UniProtKB:P39730}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAF1chr1:51048290chr14:103805509ENST00000371778-13201_57371651.0DomainUBA
HgeneFAF1chr1:51048290chr14:103805509ENST00000396153-12191_57371651.0DomainUBA
TgeneEIF5chr1:51048290chr14:103805509ENST00000216554712384_402248432.0Compositional biasNote=Asp/Glu-rich (highly acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000216554712423_429248432.0Compositional biasNote=Asp-rich (acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000392715611384_402248432.0Compositional biasNote=Asp/Glu-rich (highly acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000392715611423_429248432.0Compositional biasNote=Asp-rich (acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000558506510384_402248432.0Compositional biasNote=Asp/Glu-rich (highly acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000558506510423_429248432.0Compositional biasNote=Asp-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAF1chr1:51048290chr14:103805509ENST00000371778-1320569_646371651.0DomainUBX
HgeneFAF1chr1:51048290chr14:103805509ENST00000396153-1219569_646371651.0DomainUBX
TgeneEIF5chr1:51048290chr14:103805509ENST00000216554712196_202248432.0Compositional biasNote=Asp/Glu-rich (highly acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000392715611196_202248432.0Compositional biasNote=Asp/Glu-rich (highly acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000558506510196_202248432.0Compositional biasNote=Asp/Glu-rich (highly acidic)
TgeneEIF5chr1:51048290chr14:103805509ENST00000216554712233_392248432.0DomainW2
TgeneEIF5chr1:51048290chr14:103805509ENST00000392715611233_392248432.0DomainW2
TgeneEIF5chr1:51048290chr14:103805509ENST00000558506510233_392248432.0DomainW2
TgeneEIF5chr1:51048290chr14:103805509ENST0000021655471227_34248432.0Nucleotide bindingGTP
TgeneEIF5chr1:51048290chr14:103805509ENST0000039271561127_34248432.0Nucleotide bindingGTP
TgeneEIF5chr1:51048290chr14:103805509ENST0000055850651027_34248432.0Nucleotide bindingGTP


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Fusion Gene Sequence for FAF1-EIF5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>28231_28231_1_FAF1-EIF5_FAF1_chr1_51048290_ENST00000396153_EIF5_chr14_103805509_ENST00000216554_length(transcript)=6090nt_BP=1565nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC
TTGAACAAAATAATTGGGACTTAGTGGCAGCTATCAATGGTGTAATACCACAGGAAAATGGCATTCTACAAAGTGAATATGGAGGTGAGA
CCATACCAGGACCTGCATTTAATCCAGCAAGTCATCCAGCTTCAGCTCCTACTTCCTCTTCTTCTTCAGCGTTTCGACCTGTAATGCCAT
CCAGGCAGATTGTAGAAAGGCAACCTCGGATGCTGGACTTCAGGGTTGAATACAGAGACAGAAATGTTGATGTGGTACTTGAAGACACCT
GTACTGTTGGAGAGATTAAACAGATTCTAGAAAATGAACTTCAGATACCTGTGTCCAAAATGCTGTTAAAAGGCTGGAAGACGGGAGATG
TGGAAGACAGTACGGTCCTAAAATCTCTACACTTGCCAAAAAACAACAGTCTTTATGTCCTTACACCAGATTTGCCACCACCTTCATCAT
CTAGTCATGCTGGTGCCCTGCAGGAGTCATTAAATCAAAACTTCATGCTGATCATCACCCACCGAGAAGTCCAGCGGGAGTACAACCTGA
ACTTCTCAGGAAGCAGTACTATTCAAGAGGTAAAGAGAAATGTGTATGACCTTACAAGTATCCCCGTTCGCCACCAATTATGGGAGGGCT
GGCCAACTTCTGCTACAGACGACTCAATGTGTCTTGCTGAATCAGGGCTCTCTTATCCCTGCCATCGACTTACAGTGGGAAGAAGATCTT
CACCTGCACAGACCCGGGAACAGTCGGAAGAACAAATCACCGATGTTCATATGGTTAGTGATAGCGATGGAGATGACTTTGAAGATGCTA
CAGAATTTGGGGTGGATGATGGAGAAGTATTTGGCATGGCGTCATCTGCCTTGAGAAAATCTCCAATGATGCCAGAAAACGCAGAAAATG
AAGGAGATGCCTTATTACAATTTACAGCAGAGTTTTCTTCAAGATATGGTGATTGCCATCCTGTATTTTTTATTGGCTCATTAGAAGCTG
CTTTTCAAGAGGCCTTCTATGTGAAAGCCCGAGATAAAAAGAAAGAAGAGGGTGTTATTGATTCATCTGACAAAGAAATCGTTGCTGAAG
CAGAAAGACTGGATGTAAAAGCCATGGGCCCTCTTGTTCTAACTGAAGTTCTTTTTAATGAGAAGATTAGAGAACAGATTAAGAAATACA
GGCGCCATTTCCTACGATTTTGTCACAACAACAAAAAAGCCCAACGGTACCTTCTTCATGGTTTGGAGTGTGTGGTAGCAATGCATCAAG
CTCAGCTTATCTCCAAGATTCCACATATCTTGAAGGAGATGTACGATGCAGACCTTTTAGAAGAAGAGGTCATCATCAGCTGGTCGGAAA
AGGCCTCTAAGAAATATGTCTCCAAAGAACTTGCCAAAGAGATTCGTGTCAAAGCAGAACCATTTATAAAATGGTTGAAGGAGGCAGAGG
AAGAATCTTCTGGTGGCGAAGAAGAAGATGAAGATGAGAACATTGAGGTGGTGTATTCGAAGGCTGCCAGTGTACCGAAAGTTGAGACTG
TAAAGTCAGACAACAAGGATGACGACATCGATATTGATGCCATTTAAAGGGATGGATGCAACCTAGCTTAACAGTATAATGCTGCAAATT
TTCCTCCATTATCAGCCAGAAGTGCAACATGTATGTGCAAAAGCTAAAATGGCTTAACATCATGCTACACTTTACACTAAAAATCTATTA
CTGTGAGTGGTCTGTTATTAAGCCCAATGAGACATCTAGGGAGTCCATACACATCAGTGAGCAGATGTAGTTTGCTTATTTATAGCATGT
TTCTTTTTGAAAAACTAGTGGTGGACACATTTGGATCACATTTATACAGTTATAAAAATAAAGGTTTGATTTTGGTCGTTCTTCAGATGT
TTGGCTCTGAATGACTTAAGCTGAAGTAACTGGCTCCTTACTTTAAATGTTCTGCCATCATTTCACCTGATGAGCATTCTTGGAGCCTGC
CAGATATTGTTAGGTCCTGGGGCTGCAAAGAGGTCCTCAACAGGATGTAAAGCAAACTTAATTGTAATTAATTTATTCAGCCCATTAAGA
AAGTACTAAAGTTTTATCTCTGTAGTTCCTCAAATTGGCATCTGGTAATGTACATTGTGAGGTAGACTGATAATGAAATGACAGTGTAAC
ATCTTAACCAAGAAGTAAATATGACCTCAGTGTCCTATAAATAATGTAAGAGCAGGATTTGAAACTTGGAGAGCTGTTTTCTCATTTCAT
GTACACTTGCCCCAAATTGTCTTTGAAGTCGTGTGCATTGCACGTTGGATGAGCCAGGGAAATTATTACATTAACAAGCATTTTGTGTGT
ACGTAGTAGTTACTTTGTACTGAGAGAACTTGCTTTGGGGTGCAATTAATAAACTGATTTTATTTGGGAGAAACAAGGAAGGGTGCACTT
AACTAGCAACCTAAGCATGATTTTTCAGCTTTTGCCCTTAGGGTTTAAATTACAATTCCAAAATGTTAGACATACTGTATTTTTTCGTTC
AGTGTGGCTTTAATTTTCCCCTCTTGCAGTTTGTTCTGTAATGCCTTTTACATTTGGACACATAGTTTATGCTTTTTAGATTTTGGTTGC
TTTCTTGCCAAAATAAGTGTTAACTGTGTTTCAAACTTGATTTTCTTTCCTTTTTCTTTTTTTTTTCTTCCAGAATGTCTTATTTAAAAA
GAAAGCTAAAAGCATACTTCTAAGTCAGAGCCTCTATTTTGGTGTAAGACTTGGGATATTTTTTACTTCACATTGAATATAGCCAGGCAC
CCAAGAAGTCTGATGGCCACCTGAGTGCAGGTGACAAGGACCTGACAGAGCCCATGCAGGGCTTTAGATTTGGACACACAAGAGTTGATA
ACTTCCTCATGAACTCCTTGCCTGATCTAAACTCATATTATGGGTTCTGACTGTTTGAGTAATCATCTTCAAGGTTAAACCTCTTGGCAG
TTACCCTTTTCACAAAGTGCACAGTGGGAATCGAGAATCGATAGGGTTAATTTTGGAGCAGTGGCTTATACCATTCACCTCTGTTTTTTT
GTGATTATTTCACAGATAATGAGACCTTAATAACAAATAGGCGTAAAAAAATTTTCACATTGAAATGATAGAAACATTTGATGTAATAAA
ACTTGGTTGGCTTGATATTTTAAGGAATTGAAACCTAGCAATCTTATTGGAGAGACAAGAATTGGTCTCCAGCTGCCTTTGATCAAGATT
CGGGTGCAAGTGGAGCAGGAGCCATATACCTGGAGGGAATGTGCTTTGTCACACCAAAGAGGATTTTTTTTTCTTCAAACTTGTATGTTG
CCTAGGTTTCAAATTCTTTGCCGCAAGGCTGATCTGCTTTCATTAACTGGAATTCTGTAGGAGATACTGGTGACCTAAGCTAAGTTGCAC
TCAGCATACTCAGTGTCAAGCTAATGAGGTTCTATTATAAAGGTTCTACTTTTAATCTGAGGGAAAACATGTTCAGGGCTTCTAGAACAC
TAAAAAATTTGGCTTAAACCAGTGTTCAGTCTGGTGCCAAACTTCGAATGGAATACAAATTCACATAATCTGAACTTTGTTCACAGGTTA
TCCTAATAGAGTAATTCTTCACTTTGCTCTATTGAACTGTCTTAAGGATTTGTTTAAACAGCTAAGTTACTTGATTAAAATAATGATAAA
ATTGTATTTTGTCTTTGCTTTAATATTAAAGTTAACAAGTTTTCATTTTATAATGAGATCAAAGCATTGGAATCTGCCCTGTTTTGTAGC
CGTTGCTTTGGATTTGTGTTGGATGTATCCTGCAGTTACACTTGCCAGCCCCACTCACAAAAGTTGTTCATTTCATTGGGTCACTGGCTT
TATTTGCTAGTCTTGTCTGTGAACTGAGCATCTGCCTCAGTTTTATTACTTGAAATCTTGGCAGGTGCTTAATAGGGAACATACATACAG
CTATGTAACTGTGAATAATTGTATATATCTCTAGTTAAGAATGAGGGAATGGGGAGGTTTGCTTTCTAAACAAGTGCATTCTGAAATTGA
CTTAAAAATTTTTAGTGTGGGTCCTAAAGTTTAGAGATGGGCAAGGAGGTCTCTAATCCACCGCTTCCCGCTTGAGAAGGGAGGGGTATC
AAAATTGAGCCCCAAGCTGTTTGTTCCAGTGTACCAAGCACTGACTTTATGCCTTTGGCCTGGAGATGGCAGAAGTGAAAGCTGGCCATC
TGCAAAAAGCAGATAAGTGAGTTTGAACCTTTTGCATTTTGTTAGCTCAGTCAGTCCTCATCGTGGTCCTGAGGCATAGGTACTGTTGTA
CCAAGGTCACTTATCTAACAAAATAACCCTTCATGTATTTTAAATTTATTTGACAAGTCTGCAGACAATCCTTATCTAACCAGCTATTTT
CTTAATTGCTACAGCTTGACCTACCAGTATTCCGGAGTAACCAGCAAATGCAAAGTTGACCTTGTTCCTGCATCATCTTTTTGATGGTTC
AAATTTCAGCCTCCCTGACTACTACAAAGCCAGAGCAGTCTTAGTACCAGAAACAGTGTTGCACTTTCGTTGCATGTGCTGTGTGACCCC
AAGGGGACAGGGAGTCACTTTGGTCATCTCTGTCCCCAGTACAGATCTTGATTCATAGTGACATTCCATAAGTGGGGTGACAGCAAATGA
CTTGCAGGTAGTCTCATTGTAGGTTTGTGCACCAGAGTGACCCTGTGAGCCTTTGTTAATAGGTTGGGAGCTCAGGGTGTTTATGTCCAC
CTGTCTGGTCTAGCCAAACAGTTTTTTTCTGGGAATCAAATTTCTGTGGTTTTTATGGCCAGAAATTTTAAGGACTTGTGTGTGCTGGGA
TATGAGAATAGAAGCTACAGAGTTCTTTTCTTGGGACCTAGACTGGGAGGTGCAATGTCAGGACCTCCAGGTGAATGGTAGGATCTGAGT
TGACCCTGCAGTTCGGTTATGCAGTCAATTATTTCTTTTTAAGAGGAGGAGGATTCACTTGGGTGTTGGGATCAAATTTGGATTCTGTCC
CAGGCCTTACTGTAAAACTAGGGGATTGCCTTTCCATATCTGCTGGGGGTGGAGACCCTTATGTGCAGCACTCAATCCCACTGGAAGCCT
AATGCTGCAGTCAGAAGCAATGCCTGGCTGGGGCAGTAGGGGAAATTCCACCCAATTTTGCTATGAGCCTAAAACCTCTTTAAAAACGGT
CAGTTAACTAAAAAATAAAAATCAAGTCTTTAGGAGAGTAGAAAACACAATTAACTAAAAAGCAGGGACATCTGAAAGAGACGTATTAAG
TTAACATTTTTAAAAATCCAAATGAAAGTAAATGGAATAAATGTATCAGGTAAAGGACAAGTTGTAAGCTTGGATTTTTAGGTCTAGCAA
TACACTGTTTACAAGAGCATCACCTAAAATGTGACAAAAGATGTTGAAAGGATGAAAAAAGGTATAGTAGACATACACTAACCAAAAATG

>28231_28231_1_FAF1-EIF5_FAF1_chr1_51048290_ENST00000396153_EIF5_chr14_103805509_ENST00000216554_length(amino acids)=658AA_BP=475
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPASHPASAP
TSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTCTVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNS
LYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGWPTSATDDSMCLAESGL
SYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDATEFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYG
DCHPVFFIGSLEAAFQEAFYVKARDKKKEEGVIDSSDKEIVAEAERLDVKAMGPLVLTEVLFNEKIREQIKKYRRHFLRFCHNNKKAQRY
LLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEV

--------------------------------------------------------------
>28231_28231_2_FAF1-EIF5_FAF1_chr1_51048290_ENST00000396153_EIF5_chr14_103805509_ENST00000558506_length(transcript)=4293nt_BP=1565nt
AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC
CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC
ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC
ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC
GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG
CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC
TTGAACAAAATAATTGGGACTTAGTGGCAGCTATCAATGGTGTAATACCACAGGAAAATGGCATTCTACAAAGTGAATATGGAGGTGAGA
CCATACCAGGACCTGCATTTAATCCAGCAAGTCATCCAGCTTCAGCTCCTACTTCCTCTTCTTCTTCAGCGTTTCGACCTGTAATGCCAT
CCAGGCAGATTGTAGAAAGGCAACCTCGGATGCTGGACTTCAGGGTTGAATACAGAGACAGAAATGTTGATGTGGTACTTGAAGACACCT
GTACTGTTGGAGAGATTAAACAGATTCTAGAAAATGAACTTCAGATACCTGTGTCCAAAATGCTGTTAAAAGGCTGGAAGACGGGAGATG
TGGAAGACAGTACGGTCCTAAAATCTCTACACTTGCCAAAAAACAACAGTCTTTATGTCCTTACACCAGATTTGCCACCACCTTCATCAT
CTAGTCATGCTGGTGCCCTGCAGGAGTCATTAAATCAAAACTTCATGCTGATCATCACCCACCGAGAAGTCCAGCGGGAGTACAACCTGA
ACTTCTCAGGAAGCAGTACTATTCAAGAGGTAAAGAGAAATGTGTATGACCTTACAAGTATCCCCGTTCGCCACCAATTATGGGAGGGCT
GGCCAACTTCTGCTACAGACGACTCAATGTGTCTTGCTGAATCAGGGCTCTCTTATCCCTGCCATCGACTTACAGTGGGAAGAAGATCTT
CACCTGCACAGACCCGGGAACAGTCGGAAGAACAAATCACCGATGTTCATATGGTTAGTGATAGCGATGGAGATGACTTTGAAGATGCTA
CAGAATTTGGGGTGGATGATGGAGAAGTATTTGGCATGGCGTCATCTGCCTTGAGAAAATCTCCAATGATGCCAGAAAACGCAGAAAATG
AAGGAGATGCCTTATTACAATTTACAGCAGAGTTTTCTTCAAGATATGGTGATTGCCATCCTGTATTTTTTATTGGCTCATTAGAAGCTG
CTTTTCAAGAGGCCTTCTATGTGAAAGCCCGAGATAAAAAGAAAGAAGAGGGTGTTATTGATTCATCTGACAAAGAAATCGTTGCTGAAG
CAGAAAGACTGGATGTAAAAGCCATGGGCCCTCTTGTTCTAACTGAAGTTCTTTTTAATGAGAAGATTAGAGAACAGATTAAGAAATACA
GGCGCCATTTCCTACGATTTTGTCACAACAACAAAAAAGCCCAACGGTACCTTCTTCATGGTTTGGAGTGTGTGGTAGCAATGCATCAAG
CTCAGCTTATCTCCAAGATTCCACATATCTTGAAGGAGATGTACGATGCAGACCTTTTAGAAGAAGAGGTCATCATCAGCTGGTCGGAAA
AGGCCTCTAAGAAATATGTCTCCAAAGAACTTGCCAAAGAGATTCGTGTCAAAGCAGAACCATTTATAAAATGGTTGAAGGAGGCAGAGG
AAGAATCTTCTGGTGGCGAAGAAGAAGATGAAGATGAGAACATTGAGGTGGTGTATTCGAAGGCTGCCAGTGTACCGAAAGTTGAGACTG
TAAAGTCAGACAACAAGGATGACGACATCGATATTGATGCCATTTAAAGGGATGGATGCAACCTAGCTTAACAGTATAATGCTGCAAATT
TTCCTCCATTATCAGCCAGAAGTGCAACATGTATGTGCAAAAGCTAAAATGGCTTAACATCATGCTACACTTTACACTAAAAATCTATTA
CTGTGAGTGGTCTGTTATTAAGCCCAATGAGACATCTAGGGAGTCCATACACATCAGTGAGCAGATGTAGTTTGCTTATTTATAGCATGT
TTCTTTTTGAAAAACTAGTGGTGGACACATTTGGATCACATTTATACAGTTATAAAAATAAAGGTTTGATTTTGGTCGTTCTTCAGATGT
TTGGCTCTGAATGACTTAAGCTGAAGTAACTGGCTCCTTACTTTAAATGTTCTGCCATCATTTCACCTGATGAGCATTCTTGGAGCCTGC
CAGATATTGTTAGGTCCTGGGGCTGCAAAGAGGTCCTCAACAGGATGTAAAGCAAACTTAATTGTAATTAATTTATTCAGCCCATTAAGA
AAGTACTAAAGTTTTATCTCTGTAGTTCCTCAAATTGGCATCTGGTAATGTACATTGTGAGGTAGACTGATAATGAAATGACAGTGTAAC
ATCTTAACCAAGAAGTAAATATGACCTCAGTGTCCTATAAATAATGTAAGAGCAGGATTTGAAACTTGGAGAGCTGTTTTCTCATTTCAT
GTACACTTGCCCCAAATTGTCTTTGAAGTCGTGTGCATTGCACGTTGGATGAGCCAGGGAAATTATTACATTAACAAGCATTTTGTGTGT
ACGTAGTAGTTACTTTGTACTGAGAGAACTTGCTTTGGGGTGCAATTAATAAACTGATTTTATTTGGGAGAAACAAGGAAGGGTGCACTT
AACTAGCAACCTAAGCATGATTTTTCAGCTTTTGCCCTTAGGGTTTAAATTACAATTCCAAAATGTTAGACATACTGTATTTTTTCGTTC
AGTGTGGCTTTAATTTTCCCCTCTTGCAGTTTGTTCTGTAATGCCTTTTACATTTGGACACATAGTTTATGCTTTTTAGATTTTGGTTGC
TTTCTTGCCAAAATAAGTGTTAACTGTGTTTCAAACTTGATTTTCTTTCCTTTTTCTTTTTTTTTTCTTCCAGAATGTCTTATTTAAAAA
GAAAGCTAAAAGCATACTTCTAAGTCAGAGCCTCTATTTTGGTGTAAGACTTGGGATATTTTTTACTTCACATTGAATATAGCCAGGCAC
CCAAGAAGTCTGATGGCCACCTGAGTGCAGGTGACAAGGACCTGACAGAGCCCATGCAGGGCTTTAGATTTGGACACACAAGAGTTGATA
ACTTCCTCATGAACTCCTTGCCTGATCTAAACTCATATTATGGGTTCTGACTGTTTGAGTAATCATCTTCAAGGTTAAACCTCTTGGCAG
TTACCCTTTTCACAAAGTGCACAGTGGGAATCGAGAATCGATAGGGTTAATTTTGGAGCAGTGGCTTATACCATTCACCTCTGTTTTTTT
GTGATTATTTCACAGATAATGAGACCTTAATAACAAATAGGCGTAAAAAAATTTTCACATTGAAATGATAGAAACATTTGATGTAATAAA
ACTTGGTTGGCTTGATATTTTAAGGAATTGAAACCTAGCAATCTTATTGGAGAGACAAGAATTGGTCTCCAGCTGCCTTTGATCAAGATT
CGGGTGCAAGTGGAGCAGGAGCCATATACCTGGAGGGAATGTGCTTTGTCACACCAAAGAGGATTTTTTTTTCTTCAAACTTGTATGTTG
CCTAGGTTTCAAATTCTTTGCCGCAAGGCTGATCTGCTTTCATTAACTGGAATTCTGTAGGAGATACTGGTGACCTAAGCTAAGTTGCAC
TCAGCATACTCAGTGTCAAGCTAATGAGGTTCTATTATAAAGGTTCTACTTTTAATCTGAGGGAAAACATGTTCAGGGCTTCTAGAACAC
TAAAAAATTTGGCTTAAACCAGTGTTCAGTCTGGTGCCAAACTTCGAATGGAATACAAATTCACATAATCTGAACTTTGTTCACAGGTTA
TCCTAATAGAGTAATTCTTCACTTTGCTCTATTGAACTGTCTTAAGGATTTGTTTAAACAGCTAAGTTACTTGATTAAAATAATGATAAA

>28231_28231_2_FAF1-EIF5_FAF1_chr1_51048290_ENST00000396153_EIF5_chr14_103805509_ENST00000558506_length(amino acids)=658AA_BP=475
MPSSWPATVRPDPHPDQSSCPGCCDAGSAGCRRAAGAPEGYRVHERLALPALPRPLARRPARRLARQPLGARRRRRRWRRRSQEVPSASQ
VRASLPEPRNSAAAMASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPASHPASAP
TSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTCTVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNS
LYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGWPTSATDDSMCLAESGL
SYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDATEFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYG
DCHPVFFIGSLEAAFQEAFYVKARDKKKEEGVIDSSDKEIVAEAERLDVKAMGPLVLTEVLFNEKIREQIKKYRRHFLRFCHNNKKAQRY
LLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEV

--------------------------------------------------------------
>28231_28231_3_FAF1-EIF5_FAF1_chr1_51048290_ENST00000545823_EIF5_chr14_103805509_ENST00000216554_length(transcript)=5062nt_BP=537nt
ATACAAAGCAGGCTTGAGATGTATCCTTGCATATTTGAAGGTTCTGTGGTTATGATGAGCTGAAATGACCACTGATTAATACAGTAGCTC
TCTAAAATAATGAGGTTTCTCCACTAACGGAACCTCTTTATTTATCAAACTTATAATAAAATGAGGAATCTGCTTGAGATGTGTCTTGCT
GAATCAGGGCTCTCTTATCCCTGCCATCGACTTACAGTGGGAAGAAGATCTTCACCTGCACAGACCCGGGAACAGTCGGAAGAACAAATC
ACCGATGTTCATATGGTTAGTGATAGCGATGGAGATGACTTTGAAGATGCTACAGAATTTGGGGTGGATGATGGAGAAGTATTTGGCATG
GCGTCATCTGCCTTGAGAAAATCTCCAATGATGCCAGAAAACGCAGAAAATGAAGGAGATGCCTTATTACAATTTACAGCAGAGTTTTCT
TCAAGATATGGTGATTGCCATCCTGTATTTTTTATTGGCTCATTAGAAGCTGCTTTTCAAGAGGCCTTCTATGTGAAAGCCCGAGATAAA
AAGAAAGAAGAGGGTGTTATTGATTCATCTGACAAAGAAATCGTTGCTGAAGCAGAAAGACTGGATGTAAAAGCCATGGGCCCTCTTGTT
CTAACTGAAGTTCTTTTTAATGAGAAGATTAGAGAACAGATTAAGAAATACAGGCGCCATTTCCTACGATTTTGTCACAACAACAAAAAA
GCCCAACGGTACCTTCTTCATGGTTTGGAGTGTGTGGTAGCAATGCATCAAGCTCAGCTTATCTCCAAGATTCCACATATCTTGAAGGAG
ATGTACGATGCAGACCTTTTAGAAGAAGAGGTCATCATCAGCTGGTCGGAAAAGGCCTCTAAGAAATATGTCTCCAAAGAACTTGCCAAA
GAGATTCGTGTCAAAGCAGAACCATTTATAAAATGGTTGAAGGAGGCAGAGGAAGAATCTTCTGGTGGCGAAGAAGAAGATGAAGATGAG
AACATTGAGGTGGTGTATTCGAAGGCTGCCAGTGTACCGAAAGTTGAGACTGTAAAGTCAGACAACAAGGATGACGACATCGATATTGAT
GCCATTTAAAGGGATGGATGCAACCTAGCTTAACAGTATAATGCTGCAAATTTTCCTCCATTATCAGCCAGAAGTGCAACATGTATGTGC
AAAAGCTAAAATGGCTTAACATCATGCTACACTTTACACTAAAAATCTATTACTGTGAGTGGTCTGTTATTAAGCCCAATGAGACATCTA
GGGAGTCCATACACATCAGTGAGCAGATGTAGTTTGCTTATTTATAGCATGTTTCTTTTTGAAAAACTAGTGGTGGACACATTTGGATCA
CATTTATACAGTTATAAAAATAAAGGTTTGATTTTGGTCGTTCTTCAGATGTTTGGCTCTGAATGACTTAAGCTGAAGTAACTGGCTCCT
TACTTTAAATGTTCTGCCATCATTTCACCTGATGAGCATTCTTGGAGCCTGCCAGATATTGTTAGGTCCTGGGGCTGCAAAGAGGTCCTC
AACAGGATGTAAAGCAAACTTAATTGTAATTAATTTATTCAGCCCATTAAGAAAGTACTAAAGTTTTATCTCTGTAGTTCCTCAAATTGG
CATCTGGTAATGTACATTGTGAGGTAGACTGATAATGAAATGACAGTGTAACATCTTAACCAAGAAGTAAATATGACCTCAGTGTCCTAT
AAATAATGTAAGAGCAGGATTTGAAACTTGGAGAGCTGTTTTCTCATTTCATGTACACTTGCCCCAAATTGTCTTTGAAGTCGTGTGCAT
TGCACGTTGGATGAGCCAGGGAAATTATTACATTAACAAGCATTTTGTGTGTACGTAGTAGTTACTTTGTACTGAGAGAACTTGCTTTGG
GGTGCAATTAATAAACTGATTTTATTTGGGAGAAACAAGGAAGGGTGCACTTAACTAGCAACCTAAGCATGATTTTTCAGCTTTTGCCCT
TAGGGTTTAAATTACAATTCCAAAATGTTAGACATACTGTATTTTTTCGTTCAGTGTGGCTTTAATTTTCCCCTCTTGCAGTTTGTTCTG
TAATGCCTTTTACATTTGGACACATAGTTTATGCTTTTTAGATTTTGGTTGCTTTCTTGCCAAAATAAGTGTTAACTGTGTTTCAAACTT
GATTTTCTTTCCTTTTTCTTTTTTTTTTCTTCCAGAATGTCTTATTTAAAAAGAAAGCTAAAAGCATACTTCTAAGTCAGAGCCTCTATT
TTGGTGTAAGACTTGGGATATTTTTTACTTCACATTGAATATAGCCAGGCACCCAAGAAGTCTGATGGCCACCTGAGTGCAGGTGACAAG
GACCTGACAGAGCCCATGCAGGGCTTTAGATTTGGACACACAAGAGTTGATAACTTCCTCATGAACTCCTTGCCTGATCTAAACTCATAT
TATGGGTTCTGACTGTTTGAGTAATCATCTTCAAGGTTAAACCTCTTGGCAGTTACCCTTTTCACAAAGTGCACAGTGGGAATCGAGAAT
CGATAGGGTTAATTTTGGAGCAGTGGCTTATACCATTCACCTCTGTTTTTTTGTGATTATTTCACAGATAATGAGACCTTAATAACAAAT
AGGCGTAAAAAAATTTTCACATTGAAATGATAGAAACATTTGATGTAATAAAACTTGGTTGGCTTGATATTTTAAGGAATTGAAACCTAG
CAATCTTATTGGAGAGACAAGAATTGGTCTCCAGCTGCCTTTGATCAAGATTCGGGTGCAAGTGGAGCAGGAGCCATATACCTGGAGGGA
ATGTGCTTTGTCACACCAAAGAGGATTTTTTTTTCTTCAAACTTGTATGTTGCCTAGGTTTCAAATTCTTTGCCGCAAGGCTGATCTGCT
TTCATTAACTGGAATTCTGTAGGAGATACTGGTGACCTAAGCTAAGTTGCACTCAGCATACTCAGTGTCAAGCTAATGAGGTTCTATTAT
AAAGGTTCTACTTTTAATCTGAGGGAAAACATGTTCAGGGCTTCTAGAACACTAAAAAATTTGGCTTAAACCAGTGTTCAGTCTGGTGCC
AAACTTCGAATGGAATACAAATTCACATAATCTGAACTTTGTTCACAGGTTATCCTAATAGAGTAATTCTTCACTTTGCTCTATTGAACT
GTCTTAAGGATTTGTTTAAACAGCTAAGTTACTTGATTAAAATAATGATAAAATTGTATTTTGTCTTTGCTTTAATATTAAAGTTAACAA
GTTTTCATTTTATAATGAGATCAAAGCATTGGAATCTGCCCTGTTTTGTAGCCGTTGCTTTGGATTTGTGTTGGATGTATCCTGCAGTTA
CACTTGCCAGCCCCACTCACAAAAGTTGTTCATTTCATTGGGTCACTGGCTTTATTTGCTAGTCTTGTCTGTGAACTGAGCATCTGCCTC
AGTTTTATTACTTGAAATCTTGGCAGGTGCTTAATAGGGAACATACATACAGCTATGTAACTGTGAATAATTGTATATATCTCTAGTTAA
GAATGAGGGAATGGGGAGGTTTGCTTTCTAAACAAGTGCATTCTGAAATTGACTTAAAAATTTTTAGTGTGGGTCCTAAAGTTTAGAGAT
GGGCAAGGAGGTCTCTAATCCACCGCTTCCCGCTTGAGAAGGGAGGGGTATCAAAATTGAGCCCCAAGCTGTTTGTTCCAGTGTACCAAG
CACTGACTTTATGCCTTTGGCCTGGAGATGGCAGAAGTGAAAGCTGGCCATCTGCAAAAAGCAGATAAGTGAGTTTGAACCTTTTGCATT
TTGTTAGCTCAGTCAGTCCTCATCGTGGTCCTGAGGCATAGGTACTGTTGTACCAAGGTCACTTATCTAACAAAATAACCCTTCATGTAT
TTTAAATTTATTTGACAAGTCTGCAGACAATCCTTATCTAACCAGCTATTTTCTTAATTGCTACAGCTTGACCTACCAGTATTCCGGAGT
AACCAGCAAATGCAAAGTTGACCTTGTTCCTGCATCATCTTTTTGATGGTTCAAATTTCAGCCTCCCTGACTACTACAAAGCCAGAGCAG
TCTTAGTACCAGAAACAGTGTTGCACTTTCGTTGCATGTGCTGTGTGACCCCAAGGGGACAGGGAGTCACTTTGGTCATCTCTGTCCCCA
GTACAGATCTTGATTCATAGTGACATTCCATAAGTGGGGTGACAGCAAATGACTTGCAGGTAGTCTCATTGTAGGTTTGTGCACCAGAGT
GACCCTGTGAGCCTTTGTTAATAGGTTGGGAGCTCAGGGTGTTTATGTCCACCTGTCTGGTCTAGCCAAACAGTTTTTTTCTGGGAATCA
AATTTCTGTGGTTTTTATGGCCAGAAATTTTAAGGACTTGTGTGTGCTGGGATATGAGAATAGAAGCTACAGAGTTCTTTTCTTGGGACC
TAGACTGGGAGGTGCAATGTCAGGACCTCCAGGTGAATGGTAGGATCTGAGTTGACCCTGCAGTTCGGTTATGCAGTCAATTATTTCTTT
TTAAGAGGAGGAGGATTCACTTGGGTGTTGGGATCAAATTTGGATTCTGTCCCAGGCCTTACTGTAAAACTAGGGGATTGCCTTTCCATA
TCTGCTGGGGGTGGAGACCCTTATGTGCAGCACTCAATCCCACTGGAAGCCTAATGCTGCAGTCAGAAGCAATGCCTGGCTGGGGCAGTA
GGGGAAATTCCACCCAATTTTGCTATGAGCCTAAAACCTCTTTAAAAACGGTCAGTTAACTAAAAAATAAAAATCAAGTCTTTAGGAGAG
TAGAAAACACAATTAACTAAAAAGCAGGGACATCTGAAAGAGACGTATTAAGTTAACATTTTTAAAAATCCAAATGAAAGTAAATGGAAT
AAATGTATCAGGTAAAGGACAAGTTGTAAGCTTGGATTTTTAGGTCTAGCAATACACTGTTTACAAGAGCATCACCTAAAATGTGACAAA
AGATGTTGAAAGGATGAAAAAAGGTATAGTAGACATACACTAACCAAAAATGTAGCTCTTTGAATCTCAGAAAAAAGTAGATTTTAATAA

>28231_28231_3_FAF1-EIF5_FAF1_chr1_51048290_ENST00000545823_EIF5_chr14_103805509_ENST00000216554_length(amino acids)=312AA_BP=129
MRNLLEMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDATEFGVDDGEVFGMASSALRKSPMMPENAENEGD
ALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDKKKEEGVIDSSDKEIVAEAERLDVKAMGPLVLTEVLFNEKIREQIKKYRRH
FLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEES

--------------------------------------------------------------
>28231_28231_4_FAF1-EIF5_FAF1_chr1_51048290_ENST00000545823_EIF5_chr14_103805509_ENST00000558506_length(transcript)=3265nt_BP=537nt
ATACAAAGCAGGCTTGAGATGTATCCTTGCATATTTGAAGGTTCTGTGGTTATGATGAGCTGAAATGACCACTGATTAATACAGTAGCTC
TCTAAAATAATGAGGTTTCTCCACTAACGGAACCTCTTTATTTATCAAACTTATAATAAAATGAGGAATCTGCTTGAGATGTGTCTTGCT
GAATCAGGGCTCTCTTATCCCTGCCATCGACTTACAGTGGGAAGAAGATCTTCACCTGCACAGACCCGGGAACAGTCGGAAGAACAAATC
ACCGATGTTCATATGGTTAGTGATAGCGATGGAGATGACTTTGAAGATGCTACAGAATTTGGGGTGGATGATGGAGAAGTATTTGGCATG
GCGTCATCTGCCTTGAGAAAATCTCCAATGATGCCAGAAAACGCAGAAAATGAAGGAGATGCCTTATTACAATTTACAGCAGAGTTTTCT
TCAAGATATGGTGATTGCCATCCTGTATTTTTTATTGGCTCATTAGAAGCTGCTTTTCAAGAGGCCTTCTATGTGAAAGCCCGAGATAAA
AAGAAAGAAGAGGGTGTTATTGATTCATCTGACAAAGAAATCGTTGCTGAAGCAGAAAGACTGGATGTAAAAGCCATGGGCCCTCTTGTT
CTAACTGAAGTTCTTTTTAATGAGAAGATTAGAGAACAGATTAAGAAATACAGGCGCCATTTCCTACGATTTTGTCACAACAACAAAAAA
GCCCAACGGTACCTTCTTCATGGTTTGGAGTGTGTGGTAGCAATGCATCAAGCTCAGCTTATCTCCAAGATTCCACATATCTTGAAGGAG
ATGTACGATGCAGACCTTTTAGAAGAAGAGGTCATCATCAGCTGGTCGGAAAAGGCCTCTAAGAAATATGTCTCCAAAGAACTTGCCAAA
GAGATTCGTGTCAAAGCAGAACCATTTATAAAATGGTTGAAGGAGGCAGAGGAAGAATCTTCTGGTGGCGAAGAAGAAGATGAAGATGAG
AACATTGAGGTGGTGTATTCGAAGGCTGCCAGTGTACCGAAAGTTGAGACTGTAAAGTCAGACAACAAGGATGACGACATCGATATTGAT
GCCATTTAAAGGGATGGATGCAACCTAGCTTAACAGTATAATGCTGCAAATTTTCCTCCATTATCAGCCAGAAGTGCAACATGTATGTGC
AAAAGCTAAAATGGCTTAACATCATGCTACACTTTACACTAAAAATCTATTACTGTGAGTGGTCTGTTATTAAGCCCAATGAGACATCTA
GGGAGTCCATACACATCAGTGAGCAGATGTAGTTTGCTTATTTATAGCATGTTTCTTTTTGAAAAACTAGTGGTGGACACATTTGGATCA
CATTTATACAGTTATAAAAATAAAGGTTTGATTTTGGTCGTTCTTCAGATGTTTGGCTCTGAATGACTTAAGCTGAAGTAACTGGCTCCT
TACTTTAAATGTTCTGCCATCATTTCACCTGATGAGCATTCTTGGAGCCTGCCAGATATTGTTAGGTCCTGGGGCTGCAAAGAGGTCCTC
AACAGGATGTAAAGCAAACTTAATTGTAATTAATTTATTCAGCCCATTAAGAAAGTACTAAAGTTTTATCTCTGTAGTTCCTCAAATTGG
CATCTGGTAATGTACATTGTGAGGTAGACTGATAATGAAATGACAGTGTAACATCTTAACCAAGAAGTAAATATGACCTCAGTGTCCTAT
AAATAATGTAAGAGCAGGATTTGAAACTTGGAGAGCTGTTTTCTCATTTCATGTACACTTGCCCCAAATTGTCTTTGAAGTCGTGTGCAT
TGCACGTTGGATGAGCCAGGGAAATTATTACATTAACAAGCATTTTGTGTGTACGTAGTAGTTACTTTGTACTGAGAGAACTTGCTTTGG
GGTGCAATTAATAAACTGATTTTATTTGGGAGAAACAAGGAAGGGTGCACTTAACTAGCAACCTAAGCATGATTTTTCAGCTTTTGCCCT
TAGGGTTTAAATTACAATTCCAAAATGTTAGACATACTGTATTTTTTCGTTCAGTGTGGCTTTAATTTTCCCCTCTTGCAGTTTGTTCTG
TAATGCCTTTTACATTTGGACACATAGTTTATGCTTTTTAGATTTTGGTTGCTTTCTTGCCAAAATAAGTGTTAACTGTGTTTCAAACTT
GATTTTCTTTCCTTTTTCTTTTTTTTTTCTTCCAGAATGTCTTATTTAAAAAGAAAGCTAAAAGCATACTTCTAAGTCAGAGCCTCTATT
TTGGTGTAAGACTTGGGATATTTTTTACTTCACATTGAATATAGCCAGGCACCCAAGAAGTCTGATGGCCACCTGAGTGCAGGTGACAAG
GACCTGACAGAGCCCATGCAGGGCTTTAGATTTGGACACACAAGAGTTGATAACTTCCTCATGAACTCCTTGCCTGATCTAAACTCATAT
TATGGGTTCTGACTGTTTGAGTAATCATCTTCAAGGTTAAACCTCTTGGCAGTTACCCTTTTCACAAAGTGCACAGTGGGAATCGAGAAT
CGATAGGGTTAATTTTGGAGCAGTGGCTTATACCATTCACCTCTGTTTTTTTGTGATTATTTCACAGATAATGAGACCTTAATAACAAAT
AGGCGTAAAAAAATTTTCACATTGAAATGATAGAAACATTTGATGTAATAAAACTTGGTTGGCTTGATATTTTAAGGAATTGAAACCTAG
CAATCTTATTGGAGAGACAAGAATTGGTCTCCAGCTGCCTTTGATCAAGATTCGGGTGCAAGTGGAGCAGGAGCCATATACCTGGAGGGA
ATGTGCTTTGTCACACCAAAGAGGATTTTTTTTTCTTCAAACTTGTATGTTGCCTAGGTTTCAAATTCTTTGCCGCAAGGCTGATCTGCT
TTCATTAACTGGAATTCTGTAGGAGATACTGGTGACCTAAGCTAAGTTGCACTCAGCATACTCAGTGTCAAGCTAATGAGGTTCTATTAT
AAAGGTTCTACTTTTAATCTGAGGGAAAACATGTTCAGGGCTTCTAGAACACTAAAAAATTTGGCTTAAACCAGTGTTCAGTCTGGTGCC
AAACTTCGAATGGAATACAAATTCACATAATCTGAACTTTGTTCACAGGTTATCCTAATAGAGTAATTCTTCACTTTGCTCTATTGAACT
GTCTTAAGGATTTGTTTAAACAGCTAAGTTACTTGATTAAAATAATGATAAAATTGTATTTTGTCTTTGCTTTAATATTAAAGTTAACAA

>28231_28231_4_FAF1-EIF5_FAF1_chr1_51048290_ENST00000545823_EIF5_chr14_103805509_ENST00000558506_length(amino acids)=312AA_BP=129
MRNLLEMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDATEFGVDDGEVFGMASSALRKSPMMPENAENEGD
ALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDKKKEEGVIDSSDKEIVAEAERLDVKAMGPLVLTEVLFNEKIREQIKKYRRH
FLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEES

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FAF1-EIF5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAF1-EIF5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAF1-EIF5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource