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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAM222B-UNC5D (FusionGDB2 ID:28983)

Fusion Gene Summary for FAM222B-UNC5D

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM222B-UNC5D
Fusion gene ID: 28983
HgeneTgene
Gene symbol

FAM222B

UNC5D

Gene ID

55731

137970

Gene namefamily with sequence similarity 222 member Bunc-5 netrin receptor D
SynonymsC17orf63PRO34692|Unc5h4
Cytomap

17q11.2

8p12

Type of geneprotein-codingprotein-coding
Descriptionprotein FAM222Buncharacterized protein C17orf63netrin receptor UNC5Dnetrin receptor Unc5h4protein unc-5 homolog 4protein unc-5 homolog Dunc-5 homolog 4unc-5 homolog D
Modification date2020031320200313
UniProtAcc

Q8WU58

.
Ensembl transtripts involved in fusion geneENST00000452648, ENST00000581381, 
ENST00000581407, ENST00000582059, 
ENST00000582266, ENST00000583953, 
ENST00000341217, ENST00000577682, 
ENST00000583522, 		ENST00000287272, 
ENST00000404895, ENST00000416672, 
ENST00000420357, ENST00000449677, 
ENST00000453357, 
Fusion gene scores* DoF score29 X 15 X 15=652517 X 13 X 6=1326
# samples 4320
** MAII scorelog2(43/6525*10)=-3.92356933675515
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1326*10)=-2.72900887033786
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAM222B [Title/Abstract] AND UNC5D [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAM222B(27139227)-UNC5D(35608100), # samples:1
FAM222B(27093604)-UNC5D(35608100), # samples:1
Anticipated loss of major functional domain due to fusion event.FAM222B-UNC5D seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneUNC5D

GO:0098742

cell-cell adhesion via plasma-membrane adhesion molecules

26235030


check buttonFusion gene breakpoints across FAM222B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UNC5D (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-50-6673-01AFAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
ChimerDB4LUADTCGA-50-6673-01AFAM222Bchr17

27139227

-UNC5Dchr8

35608100

+


Top

Fusion Gene ORF analysis for FAM222B-UNC5D

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000452648ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
5UTR-3CDSENST00000452648ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
5UTR-3CDSENST00000452648ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
5UTR-3CDSENST00000452648ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
5UTR-3CDSENST00000452648ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
5UTR-3CDSENST00000452648ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
Frame-shiftENST00000452648ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000452648ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000452648ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000452648ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000452648ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000452648ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581381ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581381ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581381ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581381ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581381ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581381ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581407ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581407ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581407ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581407ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581407ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000581407ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582059ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582059ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582059ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582059ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582059ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582059ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582266ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582266ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582266ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582266ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582266ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000582266ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000583953ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000583953ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000583953ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000583953ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000583953ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
Frame-shiftENST00000583953ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000341217ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000341217ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000341217ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000341217ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000341217ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000341217ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000577682ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000577682ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000577682ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000577682ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000577682ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000577682ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000583522ENST00000287272FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000583522ENST00000404895FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000583522ENST00000416672FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000583522ENST00000420357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000583522ENST00000449677FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
In-frameENST00000583522ENST00000453357FAM222Bchr17

27093604

-UNC5Dchr8

35608100

+
intron-3CDSENST00000341217ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000341217ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000341217ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000341217ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000341217ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000341217ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000577682ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000577682ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000577682ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000577682ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000577682ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000577682ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581381ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581381ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581381ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581381ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581381ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581381ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581407ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581407ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581407ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581407ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581407ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000581407ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582059ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582059ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582059ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582059ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582059ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582059ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582266ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582266ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582266ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582266ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582266ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000582266ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583522ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583522ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583522ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583522ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583522ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583522ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583953ENST00000287272FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583953ENST00000404895FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583953ENST00000416672FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583953ENST00000420357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583953ENST00000449677FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+
intron-3CDSENST00000583953ENST00000453357FAM222Bchr17

27139227

-UNC5Dchr8

35608100

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341217FAM222Bchr1727093604-ENST00000287272UNC5Dchr835608100+72122982831224313
ENST00000341217FAM222Bchr1727093604-ENST00000453357UNC5Dchr835608100+53242982831224313
ENST00000341217FAM222Bchr1727093604-ENST00000404895UNC5Dchr835608100+12872982831224313
ENST00000341217FAM222Bchr1727093604-ENST00000420357UNC5Dchr835608100+15102982831224313
ENST00000341217FAM222Bchr1727093604-ENST00000416672UNC5Dchr835608100+18702982831224313
ENST00000341217FAM222Bchr1727093604-ENST00000449677UNC5Dchr835608100+19722982831224313
ENST00000577682FAM222Bchr1727093604-ENST00000287272UNC5Dchr835608100+71792652501191313
ENST00000577682FAM222Bchr1727093604-ENST00000453357UNC5Dchr835608100+52912652501191313
ENST00000577682FAM222Bchr1727093604-ENST00000404895UNC5Dchr835608100+12542652501191313
ENST00000577682FAM222Bchr1727093604-ENST00000420357UNC5Dchr835608100+14772652501191313
ENST00000577682FAM222Bchr1727093604-ENST00000416672UNC5Dchr835608100+18372652501191313
ENST00000577682FAM222Bchr1727093604-ENST00000449677UNC5Dchr835608100+19392652501191313
ENST00000583522FAM222Bchr1727093604-ENST00000287272UNC5Dchr835608100+72763623471288313
ENST00000583522FAM222Bchr1727093604-ENST00000453357UNC5Dchr835608100+53883623471288313
ENST00000583522FAM222Bchr1727093604-ENST00000404895UNC5Dchr835608100+13513623471288313
ENST00000583522FAM222Bchr1727093604-ENST00000420357UNC5Dchr835608100+15743623471288313
ENST00000583522FAM222Bchr1727093604-ENST00000416672UNC5Dchr835608100+19343623471288313
ENST00000583522FAM222Bchr1727093604-ENST00000449677UNC5Dchr835608100+20363623471288313

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341217ENST00000287272FAM222Bchr1727093604-UNC5Dchr835608100+0.0016713110.99832875
ENST00000341217ENST00000453357FAM222Bchr1727093604-UNC5Dchr835608100+0.0020678410.9979322
ENST00000341217ENST00000404895FAM222Bchr1727093604-UNC5Dchr835608100+0.0177244670.9822756
ENST00000341217ENST00000420357FAM222Bchr1727093604-UNC5Dchr835608100+0.0105507880.98944926
ENST00000341217ENST00000416672FAM222Bchr1727093604-UNC5Dchr835608100+0.0085725080.99142754
ENST00000341217ENST00000449677FAM222Bchr1727093604-UNC5Dchr835608100+0.0077698570.9922301
ENST00000577682ENST00000287272FAM222Bchr1727093604-UNC5Dchr835608100+0.0016679380.9983321
ENST00000577682ENST00000453357FAM222Bchr1727093604-UNC5Dchr835608100+0.0020633040.9979367
ENST00000577682ENST00000404895FAM222Bchr1727093604-UNC5Dchr835608100+0.0152578470.98474216
ENST00000577682ENST00000420357FAM222Bchr1727093604-UNC5Dchr835608100+0.0100253860.98997456
ENST00000577682ENST00000416672FAM222Bchr1727093604-UNC5Dchr835608100+0.0079276660.9920723
ENST00000577682ENST00000449677FAM222Bchr1727093604-UNC5Dchr835608100+0.006847570.9931524
ENST00000583522ENST00000287272FAM222Bchr1727093604-UNC5Dchr835608100+0.0016810830.99831885
ENST00000583522ENST00000453357FAM222Bchr1727093604-UNC5Dchr835608100+0.0021040080.99789596
ENST00000583522ENST00000404895FAM222Bchr1727093604-UNC5Dchr835608100+0.0164517240.9835482
ENST00000583522ENST00000420357FAM222Bchr1727093604-UNC5Dchr835608100+0.0104868780.9895131
ENST00000583522ENST00000416672FAM222Bchr1727093604-UNC5Dchr835608100+0.0089703640.9910296
ENST00000583522ENST00000449677FAM222Bchr1727093604-UNC5Dchr835608100+0.007822230.9921778

Top

Fusion Genomic Features for FAM222B-UNC5D


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FAM222Bchr1727093603-UNC5Dchr835608099+0.0038640850.9961359
FAM222Bchr1727139226-UNC5Dchr835608099+0.0005855320.99941444
FAM222Bchr1727093603-UNC5Dchr835608099+0.0038640850.9961359
FAM222Bchr1727139226-UNC5Dchr835608099+0.0005855320.99941444

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FAM222B-UNC5D


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:27139227/chr8:35608100)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FAM222B

Q8WU58

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004048951117859_936645954.0DomainNote=Death
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004533571117859_936640949.0DomainNote=Death

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAM222Bchr17:27093604chr8:35608100ENST00000341217-23148_22027563.0Compositional biasNote=Gln-rich
HgeneFAM222Bchr17:27093604chr8:35608100ENST00000452648-23148_22027563.0Compositional biasNote=Gln-rich
HgeneFAM222Bchr17:27093604chr8:35608100ENST00000581407-23148_22027563.0Compositional biasNote=Gln-rich
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004048951117153_244645954.0DomainNote=Ig-like C2-type
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004048951117252_306645954.0DomainTSP type-1 1
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004048951117308_360645954.0DomainTSP type-1 2
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004048951117542_682645954.0DomainZU5
TgeneUNC5Dchr17:27093604chr8:35608100ENST00000404895111754_151645954.0DomainNote=Ig-like
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004533571117153_244640949.0DomainNote=Ig-like C2-type
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004533571117252_306640949.0DomainTSP type-1 1
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004533571117308_360640949.0DomainTSP type-1 2
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004533571117542_682640949.0DomainZU5
TgeneUNC5Dchr17:27093604chr8:35608100ENST00000453357111754_151640949.0DomainNote=Ig-like
TgeneUNC5Dchr17:27093604chr8:35608100ENST00000404895111733_379645954.0Topological domainExtracellular
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004048951117401_953645954.0Topological domainCytoplasmic
TgeneUNC5Dchr17:27093604chr8:35608100ENST00000453357111733_379640949.0Topological domainExtracellular
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004533571117401_953640949.0Topological domainCytoplasmic
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004048951117380_400645954.0TransmembraneHelical
TgeneUNC5Dchr17:27093604chr8:35608100ENST000004533571117380_400640949.0TransmembraneHelical


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Fusion Gene Sequence for FAM222B-UNC5D


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>28983_28983_1_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000287272_length(transcript)=7212nt_BP=298nt
ACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGC
GGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGAGTAGTGGTGGAGGGGGAGTGTTCATTACAGTGTG
AGCCACTGCCCCATGTTGTGTTGATGCCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCAC
ACGCAGATGAACACTGGACTTCAGAAATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTG
TCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTT
TGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGA
TGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGA
TATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCT
GCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACA
GATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGAC
TGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCA
GATGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGA
AGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTC
AGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGC
TTGGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTC
CCCTGTTGAAGAAACTAAATTTTATATAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCT
CCTTGGAATCCACATTTGGGTTAACTCCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTA
TGATAATGCTGGGAAGGCAGAGATTGATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTA
CTAGATTGTCAGAGTTTTCTACCAACTGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAAC
CCATTTGTATGACTTCAACAACGTCAAGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTA
GCCACTTAATGGAGACACAATGGAGAGGTAAGACAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAA
ATCTACCCTTATTCTTTCTTCCTCTTCCTTACCCCTTGCAGTAGGGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGT
TTTTTCTAACACAACAAAGTGGGACCATCTCTATTCCCATCTAAGCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGG
ATATGGGGACAGGAGAGATTAAAGCAGGTTCAAAAACACATGAACTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACAC
GTGTTGATCTAGTTATCTAACATTGTTGTTATAAGAAAATGAGTTTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGG
GTACTGTGTCATCACAAAATCTCTCAGTAAGGCTATATGTGATCCTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAAT
GATATCTGAGTAAATAGACTTGAGGAATCCTCTACCACAGTGTCCCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTAT
TCAGCCTCCCTGAATATGCTTTCTCTATAGAACCACTAACATATGGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATA
TTGTGGAAGATTGAAATCCACAGATAATTCATGACCCTCATCTTATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAG
ATGTCCTGGTAGACTAAAGGTGAACAGATTTGCTCTTGCTCATCTTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAA
GTCAAGGACCCAGATGAACCACAAGGCAGCTAGTCAGCTACTTAGAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGG
TGGGGAGTTGGGGAGTACTTGGCAGTTGGGATATGATCCATTTTTTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAAT
GTTGTGAATCTCCATGCCAAGTGAAAAAGGCCTAAAGATGAGTTGAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTG
TTGGCCATTTTCTCTAACTAACATGTGGTATGTATGGTCCCCTATATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCT
TTTCTCAGGAACCAAAGGCTTATGATGTAGGACAAAGAAATCATCTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGG
AAAACACCCTTTTGCTAGTGTGCTTAACTTATTTATTTCTTCTAGGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCA
CTGATAGAATTTCTGAAAGAGAAAGAGAAGTAGATGGTCAACCAGTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCAT
TCACTATTGAGTAAAAACTTGTAGAAAGCACATTATAGAGCTTATGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGC
ATTTTCCCTCTTCCCTTCTAATGGGCATTATAATTGTTTCATCTACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACAT
TTTAAGTATTTTTAAATAGATGAAAATTCTAAATGATTTTCCCTCAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAAT
CCCTGAATGTCTGGAGTTACCTCCCATGGATTTTTTTTTCCTTTGGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAA
CAAAGGAGGAAGTTAACTTAATTCACCTCAGACTTCAGCCTAAGATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGT
TTCTTTTACTTATTGCTGCTAGGATCCTACATAGGATTTCTATAGAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGT
ATGTTACAATACAATTTCAAAGAGAACCCACATTTGTGAGATTTACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAA
AAGTGAGCTTACACTTGAACTTAGTTATTCACTGTGACCTAAATTTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCT
TGAAAGAGATTTACTCATCTATCCAAGCACTTAATTTGGAAATTTTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAG
TACTTGGTAAGTTACTTAAAATTTTTACAAAAATATCCCACTCAATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCAT
GCTTTAAATATGGCTTTAAATTATGCCACCAAAATGGTGCACTTCACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTT
TACAACATTGCTTCTACATTCTTACTGGTTTACATTAAAATCCTTTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCA
TTTACCAGTGCAGGAAGTCTCATAAAACTCAGATGTACTCCCACAAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACAC
AGTTCTCTTTAAAGAGAAGAACTTTTTTATTATTATTTTTATCTCCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTT
CAGTTGTCTTTGGGAGGGGATGTTAAGTCAAATCACTAAAACAGGGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCC
TTGAGAAACATTCTCAGCATCAGGATTGATAAACAAATGTAGATGATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAA
ACTTCTGGCAAATTTACCTGTGAATTTCAAAATGTTATAAAATCTCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATT
TCTTAGTCCCTCTGCCCTCTGTAAATGTGTTGAGTGATATAGCTATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAG
CTCTGTAAAGGTCACAGGAATCGTGAAGGAGCTGAGAAATCTTCCTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGA
AACATTGCAGAGTTTGAATCCTCAGTAACTCTCATTGACTGGATTAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTAC
AGAGAATGACACAATTTTATTCGCCTTTGGTGTTAGTTGCCATAGTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCA
CCGTTTCCGTAGTTTCCACTGTTTTGTCTGCATAGAATTTTCCTGAACTACAAGCAAAAATGTATTTTGTCCAATGTCACAAAAGTGAAA
ATGTTACTAATCTTAGATGTGTTGCATATTTTGTGTTTTTACGTTCCAAACTCTTTCAAAAGCTGCCGTTACAAAGCTGTTTGGCTGTAT
TGACAGCATGTGGTGTTTTTACAAAAGCAATTCTAGGAGAGCCAGTGTCTACCATGAACTCCTGACATCCCCACTCCAGGGTCATTCATG
ACATTGAAATGGCAACTTGTACACTGTAATTCTTCGAAAAGTAACAGGGGATGGAAATCAGACCTGGCCGTTAGTCACTAGTGTGTAGTA
CCGTGATCTGAAGTAGGAAATTTAACTGACATAGAATAATTGTGGTTTTTGAAGCAGCTACTCATTGCTTTTTCCTTTTGCTGTGAAGAT
CATGGATTGGGAATGTCCTCGTGAGGTGGACCTAAGGCAGTAACATTTAAACTTCATGTCCTAGCACCCGCCCTCCATCTGACCCAAAGA
TAAAAAAGGCATCAAGCTTCATGGTTATGCCTAAGCTTAAAAATTCCCTTCCCCACTACTAATATTGAGTTCAGCAGGGCCCCATCTTAC
TTATTTTTCAAAAAAGTTATAGCTTTGAATTATAGACTATATTACTAAATTTGGTAAGGTAGTTCTTTGCATGAATGGGAATGTGTGTCA
AAATACTTTCACAAAAGGCATGATTACAATGGAAATGCCCCTTTGCCTCCAGTTTTGCTAACCCTAAAAAGTATTTCACTAATTTCAAGC
ACTGTTTACACTCAAATCCCAAAATTGGCCAAATTATATAATTCTCTTAAATTTTCATTTCTGTAGGTGGAGATTTAACTATGGTTCTGG
TGAATCATAGAAGGGAGAGACAATATTTGAGGGGAGTTTATCAGCAGAATATCATGCCTTATGACCCCATTACTGAAACACAGACATTAC
AATCAGAAATAGACCTAATAATTCCAATATCCCTCCATTAACTAGTTCCAGTGATGCTGAGAGACACAGCACCCTGTGCCAGGTATCAGA
AATATAAGCCTCAGCAGAGGGTAACTGAAAACTTTCAATCAGAAACACTCTCCAAGGCTTATGGCTAGATTATGTAGGTCACTACCATTC
AAAACTTTTCTATACAAAGGTGGAAAAGCACTCAGAATCTGGGAATTTTCTGGTTGGAAGAACAATGTTCTCCTTTTCCAAATTGGAATA
AAGACTCAGAATTACCCATTCTTCATAATCATGTCTGATTGGTACATACACTCCAGGAAGTCTCAACCTAGAAACATTTCCAACCTAAGC
ATTTAAAGGAAAACTGGCTCATTCTTCTGACCCAAACTCAAAAAATATGAGTACTTGCGTACCTCCATTTCTGCATGAAGATTTTAAAAC
AGATTTCATTTTTTTCTGTTTATTTTGGGAAGGTGCGTGGGGGTGTTCTTTCAAGTGATTCACATCTCAAACCCATACCACTCTCAACTT
TTATTTGATGTGTTCAAAGCCAAAAAATAAAATAAAATAAAGCAGGGCTGAACACTTAATTTGACATGAAGCTGAAGGACTGAGCAAGCC
AGAGGAGAGAGGTTGAATGAAGCATAGCCTTGGCTTCATACCACACTTTTTGTGCCTTGTATTATCAATGTAAATTCTGAATGTTGTACA
GTAAACTTGGATGGACTTCTTAGAAAAGGCTGCACTGGCTTCTTTTTCAGCACATGTACATATCTATAAATATATATACATATATATTTG
GTAATGCCAAACAGCTCTGTTATATTGTATTGAACAAAATGGACGGTTTGGATGTTTTATGTCGAGTTTGCAAAAAAAAAAAAAAAAAAA
AAAACTGGATGGTTGCAGACTTTTCAAGATAAATGTACAGACGTAAATTACTGCATATCAGTTATTTATGAATAAAGAGTCTTTTATTGA

>28983_28983_1_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000287272_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

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>28983_28983_2_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000404895_length(transcript)=1287nt_BP=298nt
ACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGC
GGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGAGTAGTGGTGGAGGGGGAGTGTTCATTACAGTGTG
AGCCACTGCCCCATGTTGTGTTGATGCCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCAC
ACGCAGATGAACACTGGACTTCAGAAATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTG
TCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTT
TGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGA
TGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGA
TATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCT
GCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACA
GATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGAC
TGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCA
GATGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGA
AGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTC
AGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGC

>28983_28983_2_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000404895_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

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>28983_28983_3_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000416672_length(transcript)=1870nt_BP=298nt
ACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGC
GGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGAGTAGTGGTGGAGGGGGAGTGTTCATTACAGTGTG
AGCCACTGCCCCATGTTGTGTTGATGCCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCAC
ACGCAGATGAACACTGGACTTCAGAAATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTG
TCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTT
TGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGA
TGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGA
TATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCT
GCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACA
GATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGAC
TGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCA
GATGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGA
AGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTC
AGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGC
TTGGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTC
CCCTGTTGAAGAAACTAAATTTTATATAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCT
CCTTGGAATCCACATTTGGGTTAACTCCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTA
TGATAATGCTGGGAAGGCAGAGATTGATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTA
CTAGATTGTCAGAGTTTTCTACCAACTGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAAC
CCATTTGTATGACTTCAACAACGTCAAGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTA

>28983_28983_3_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000416672_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

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>28983_28983_4_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000420357_length(transcript)=1510nt_BP=298nt
ACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGC
GGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGAGTAGTGGTGGAGGGGGAGTGTTCATTACAGTGTG
AGCCACTGCCCCATGTTGTGTTGATGCCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCAC
ACGCAGATGAACACTGGACTTCAGAAATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTG
TCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTT
TGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGA
TGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGA
TATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCT
GCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACA
GATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGAC
TGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCA
GATGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGA
AGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTC
AGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGC
TTGGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTC
CCCTGTTGAAGAAACTAAATTTTATATAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCT

>28983_28983_4_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000420357_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_5_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000449677_length(transcript)=1972nt_BP=298nt
ACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGC
GGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGAGTAGTGGTGGAGGGGGAGTGTTCATTACAGTGTG
AGCCACTGCCCCATGTTGTGTTGATGCCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCAC
ACGCAGATGAACACTGGACTTCAGAAATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTG
TCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTT
TGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGA
TGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGA
TATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCT
GCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACA
GATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGAC
TGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCA
GATGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGA
AGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTC
AGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGC
TTGGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTC
CCCTGTTGAAGAAACTAAATTTTATATAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCT
CCTTGGAATCCACATTTGGGTTAACTCCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTA
TGATAATGCTGGGAAGGCAGAGATTGATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTA
CTAGATTGTCAGAGTTTTCTACCAACTGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAAC
CCATTTGTATGACTTCAACAACGTCAAGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTA
GCCACTTAATGGAGACACAATGGAGAGGTAAGACAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAA

>28983_28983_5_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000449677_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_6_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000453357_length(transcript)=5324nt_BP=298nt
ACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGC
GGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGAGTAGTGGTGGAGGGGGAGTGTTCATTACAGTGTG
AGCCACTGCCCCATGTTGTGTTGATGCCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCAC
ACGCAGATGAACACTGGACTTCAGAAATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTG
TCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTT
TGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGA
TGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGA
TATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCT
GCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACA
GATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGAC
TGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCA
GATGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGA
AGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTC
AGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGC
TTGGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTC
CCCTGTTGAAGAAACTAAATTTTATATAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCT
CCTTGGAATCCACATTTGGGTTAACTCCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTA
TGATAATGCTGGGAAGGCAGAGATTGATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTA
CTAGATTGTCAGAGTTTTCTACCAACTGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAAC
CCATTTGTATGACTTCAACAACGTCAAGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTA
GCCACTTAATGGAGACACAATGGAGAGGTAAGACAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAA
ATCTACCCTTATTCTTTCTTCCTCTTCCTTACCCCTTGCAGTAGGGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGT
TTTTTCTAACACAACAAAGTGGGACCATCTCTATTCCCATCTAAGCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGG
ATATGGGGACAGGAGAGATTAAAGCAGGTTCAAAAACACATGAACTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACAC
GTGTTGATCTAGTTATCTAACATTGTTGTTATAAGAAAATGAGTTTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGG
GTACTGTGTCATCACAAAATCTCTCAGTAAGGCTATATGTGATCCTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAAT
GATATCTGAGTAAATAGACTTGAGGAATCCTCTACCACAGTGTCCCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTAT
TCAGCCTCCCTGAATATGCTTTCTCTATAGAACCACTAACATATGGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATA
TTGTGGAAGATTGAAATCCACAGATAATTCATGACCCTCATCTTATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAG
ATGTCCTGGTAGACTAAAGGTGAACAGATTTGCTCTTGCTCATCTTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAA
GTCAAGGACCCAGATGAACCACAAGGCAGCTAGTCAGCTACTTAGAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGG
TGGGGAGTTGGGGAGTACTTGGCAGTTGGGATATGATCCATTTTTTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAAT
GTTGTGAATCTCCATGCCAAGTGAAAAAGGCCTAAAGATGAGTTGAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTG
TTGGCCATTTTCTCTAACTAACATGTGGTATGTATGGTCCCCTATATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCT
TTTCTCAGGAACCAAAGGCTTATGATGTAGGACAAAGAAATCATCTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGG
AAAACACCCTTTTGCTAGTGTGCTTAACTTATTTATTTCTTCTAGGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCA
CTGATAGAATTTCTGAAAGAGAAAGAGAAGTAGATGGTCAACCAGTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCAT
TCACTATTGAGTAAAAACTTGTAGAAAGCACATTATAGAGCTTATGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGC
ATTTTCCCTCTTCCCTTCTAATGGGCATTATAATTGTTTCATCTACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACAT
TTTAAGTATTTTTAAATAGATGAAAATTCTAAATGATTTTCCCTCAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAAT
CCCTGAATGTCTGGAGTTACCTCCCATGGATTTTTTTTTCCTTTGGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAA
CAAAGGAGGAAGTTAACTTAATTCACCTCAGACTTCAGCCTAAGATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGT
TTCTTTTACTTATTGCTGCTAGGATCCTACATAGGATTTCTATAGAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGT
ATGTTACAATACAATTTCAAAGAGAACCCACATTTGTGAGATTTACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAA
AAGTGAGCTTACACTTGAACTTAGTTATTCACTGTGACCTAAATTTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCT
TGAAAGAGATTTACTCATCTATCCAAGCACTTAATTTGGAAATTTTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAG
TACTTGGTAAGTTACTTAAAATTTTTACAAAAATATCCCACTCAATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCAT
GCTTTAAATATGGCTTTAAATTATGCCACCAAAATGGTGCACTTCACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTT
TACAACATTGCTTCTACATTCTTACTGGTTTACATTAAAATCCTTTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCA
TTTACCAGTGCAGGAAGTCTCATAAAACTCAGATGTACTCCCACAAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACAC
AGTTCTCTTTAAAGAGAAGAACTTTTTTATTATTATTTTTATCTCCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTT
CAGTTGTCTTTGGGAGGGGATGTTAAGTCAAATCACTAAAACAGGGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCC
TTGAGAAACATTCTCAGCATCAGGATTGATAAACAAATGTAGATGATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAA
ACTTCTGGCAAATTTACCTGTGAATTTCAAAATGTTATAAAATCTCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATT
TCTTAGTCCCTCTGCCCTCTGTAAATGTGTTGAGTGATATAGCTATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAG
CTCTGTAAAGGTCACAGGAATCGTGAAGGAGCTGAGAAATCTTCCTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGA
AACATTGCAGAGTTTGAATCCTCAGTAACTCTCATTGACTGGATTAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTAC
AGAGAATGACACAATTTTATTCGCCTTTGGTGTTAGTTGCCATAGTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCA
CCGTTTCCGTAGTTTCCACTGTTTTGTCTGCATAGAATTTTCCTGAACTACAAGCAAAAATGTATTTTGTCCAATGTCACAAAAGTGAAA

>28983_28983_6_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000341217_UNC5D_chr8_35608100_ENST00000453357_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_7_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000287272_length(transcript)=7179nt_BP=265nt
AGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGG
CCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAGTTTTTAAACCAGTGTGAGCCACTGCCCCATGTTGTGTTGATGCCAATCT
GCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAAATGAAGT
GATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGC
GCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAA
CTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGA
ACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATT
CACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCC
CACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAG
TGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCAT
CAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAA
TTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTC
CCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTA
CAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAAAGAGGCC
GCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATATAGGTAA
AACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACTCCTCAGA
TTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTGATTAAGT
GCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAACTGGCATC
TGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCAAGGAGGG
CATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGAGGTAAGA
CAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTTCTTCCTCTTCCTTACC
CCTTGCAGTAGGGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGTTTTTTCTAACACAACAAAGTGGGACCATCTCTA
TTCCCATCTAAGCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGGATATGGGGACAGGAGAGATTAAAGCAGGTTCAA
AAACACATGAACTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACACGTGTTGATCTAGTTATCTAACATTGTTGTTATA
AGAAAATGAGTTTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGGGTACTGTGTCATCACAAAATCTCTCAGTAAGGC
TATATGTGATCCTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAATGATATCTGAGTAAATAGACTTGAGGAATCCTCT
ACCACAGTGTCCCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTATTCAGCCTCCCTGAATATGCTTTCTCTATAGAAC
CACTAACATATGGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATATTGTGGAAGATTGAAATCCACAGATAATTCATG
ACCCTCATCTTATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAGATGTCCTGGTAGACTAAAGGTGAACAGATTTGC
TCTTGCTCATCTTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAAGTCAAGGACCCAGATGAACCACAAGGCAGCTAG
TCAGCTACTTAGAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGGTGGGGAGTTGGGGAGTACTTGGCAGTTGGGATA
TGATCCATTTTTTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAATGTTGTGAATCTCCATGCCAAGTGAAAAAGGCCT
AAAGATGAGTTGAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTGTTGGCCATTTTCTCTAACTAACATGTGGTATGT
ATGGTCCCCTATATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCTTTTCTCAGGAACCAAAGGCTTATGATGTAGGAC
AAAGAAATCATCTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGGAAAACACCCTTTTGCTAGTGTGCTTAACTTATT
TATTTCTTCTAGGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCACTGATAGAATTTCTGAAAGAGAAAGAGAAGTAG
ATGGTCAACCAGTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCATTCACTATTGAGTAAAAACTTGTAGAAAGCACAT
TATAGAGCTTATGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGCATTTTCCCTCTTCCCTTCTAATGGGCATTATAA
TTGTTTCATCTACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACATTTTAAGTATTTTTAAATAGATGAAAATTCTAAA
TGATTTTCCCTCAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAATCCCTGAATGTCTGGAGTTACCTCCCATGGATTT
TTTTTTCCTTTGGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAACAAAGGAGGAAGTTAACTTAATTCACCTCAGAC
TTCAGCCTAAGATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGTTTCTTTTACTTATTGCTGCTAGGATCCTACATA
GGATTTCTATAGAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGTATGTTACAATACAATTTCAAAGAGAACCCACAT
TTGTGAGATTTACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAAAAGTGAGCTTACACTTGAACTTAGTTATTCACT
GTGACCTAAATTTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCTTGAAAGAGATTTACTCATCTATCCAAGCACTTA
ATTTGGAAATTTTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAGTACTTGGTAAGTTACTTAAAATTTTTACAAAAA
TATCCCACTCAATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCATGCTTTAAATATGGCTTTAAATTATGCCACCAAA
ATGGTGCACTTCACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTTTACAACATTGCTTCTACATTCTTACTGGTTTAC
ATTAAAATCCTTTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCATTTACCAGTGCAGGAAGTCTCATAAAACTCAGA
TGTACTCCCACAAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACACAGTTCTCTTTAAAGAGAAGAACTTTTTTATTAT
TATTTTTATCTCCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTTCAGTTGTCTTTGGGAGGGGATGTTAAGTCAAAT
CACTAAAACAGGGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCCTTGAGAAACATTCTCAGCATCAGGATTGATAAA
CAAATGTAGATGATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAAACTTCTGGCAAATTTACCTGTGAATTTCAAAAT
GTTATAAAATCTCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATTTCTTAGTCCCTCTGCCCTCTGTAAATGTGTTGA
GTGATATAGCTATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAGCTCTGTAAAGGTCACAGGAATCGTGAAGGAGCT
GAGAAATCTTCCTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGAAACATTGCAGAGTTTGAATCCTCAGTAACTCTC
ATTGACTGGATTAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTACAGAGAATGACACAATTTTATTCGCCTTTGGTGT
TAGTTGCCATAGTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCACCGTTTCCGTAGTTTCCACTGTTTTGTCTGCAT
AGAATTTTCCTGAACTACAAGCAAAAATGTATTTTGTCCAATGTCACAAAAGTGAAAATGTTACTAATCTTAGATGTGTTGCATATTTTG
TGTTTTTACGTTCCAAACTCTTTCAAAAGCTGCCGTTACAAAGCTGTTTGGCTGTATTGACAGCATGTGGTGTTTTTACAAAAGCAATTC
TAGGAGAGCCAGTGTCTACCATGAACTCCTGACATCCCCACTCCAGGGTCATTCATGACATTGAAATGGCAACTTGTACACTGTAATTCT
TCGAAAAGTAACAGGGGATGGAAATCAGACCTGGCCGTTAGTCACTAGTGTGTAGTACCGTGATCTGAAGTAGGAAATTTAACTGACATA
GAATAATTGTGGTTTTTGAAGCAGCTACTCATTGCTTTTTCCTTTTGCTGTGAAGATCATGGATTGGGAATGTCCTCGTGAGGTGGACCT
AAGGCAGTAACATTTAAACTTCATGTCCTAGCACCCGCCCTCCATCTGACCCAAAGATAAAAAAGGCATCAAGCTTCATGGTTATGCCTA
AGCTTAAAAATTCCCTTCCCCACTACTAATATTGAGTTCAGCAGGGCCCCATCTTACTTATTTTTCAAAAAAGTTATAGCTTTGAATTAT
AGACTATATTACTAAATTTGGTAAGGTAGTTCTTTGCATGAATGGGAATGTGTGTCAAAATACTTTCACAAAAGGCATGATTACAATGGA
AATGCCCCTTTGCCTCCAGTTTTGCTAACCCTAAAAAGTATTTCACTAATTTCAAGCACTGTTTACACTCAAATCCCAAAATTGGCCAAA
TTATATAATTCTCTTAAATTTTCATTTCTGTAGGTGGAGATTTAACTATGGTTCTGGTGAATCATAGAAGGGAGAGACAATATTTGAGGG
GAGTTTATCAGCAGAATATCATGCCTTATGACCCCATTACTGAAACACAGACATTACAATCAGAAATAGACCTAATAATTCCAATATCCC
TCCATTAACTAGTTCCAGTGATGCTGAGAGACACAGCACCCTGTGCCAGGTATCAGAAATATAAGCCTCAGCAGAGGGTAACTGAAAACT
TTCAATCAGAAACACTCTCCAAGGCTTATGGCTAGATTATGTAGGTCACTACCATTCAAAACTTTTCTATACAAAGGTGGAAAAGCACTC
AGAATCTGGGAATTTTCTGGTTGGAAGAACAATGTTCTCCTTTTCCAAATTGGAATAAAGACTCAGAATTACCCATTCTTCATAATCATG
TCTGATTGGTACATACACTCCAGGAAGTCTCAACCTAGAAACATTTCCAACCTAAGCATTTAAAGGAAAACTGGCTCATTCTTCTGACCC
AAACTCAAAAAATATGAGTACTTGCGTACCTCCATTTCTGCATGAAGATTTTAAAACAGATTTCATTTTTTTCTGTTTATTTTGGGAAGG
TGCGTGGGGGTGTTCTTTCAAGTGATTCACATCTCAAACCCATACCACTCTCAACTTTTATTTGATGTGTTCAAAGCCAAAAAATAAAAT
AAAATAAAGCAGGGCTGAACACTTAATTTGACATGAAGCTGAAGGACTGAGCAAGCCAGAGGAGAGAGGTTGAATGAAGCATAGCCTTGG
CTTCATACCACACTTTTTGTGCCTTGTATTATCAATGTAAATTCTGAATGTTGTACAGTAAACTTGGATGGACTTCTTAGAAAAGGCTGC
ACTGGCTTCTTTTTCAGCACATGTACATATCTATAAATATATATACATATATATTTGGTAATGCCAAACAGCTCTGTTATATTGTATTGA
ACAAAATGGACGGTTTGGATGTTTTATGTCGAGTTTGCAAAAAAAAAAAAAAAAAAAAAAACTGGATGGTTGCAGACTTTTCAAGATAAA

>28983_28983_7_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000287272_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_8_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000404895_length(transcript)=1254nt_BP=265nt
AGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGG
CCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAGTTTTTAAACCAGTGTGAGCCACTGCCCCATGTTGTGTTGATGCCAATCT
GCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAAATGAAGT
GATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGC
GCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAA
CTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGA
ACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATT
CACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCC
CACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAG
TGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCAT
CAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAA
TTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTC
CCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTA

>28983_28983_8_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000404895_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_9_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000416672_length(transcript)=1837nt_BP=265nt
AGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGG
CCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAGTTTTTAAACCAGTGTGAGCCACTGCCCCATGTTGTGTTGATGCCAATCT
GCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAAATGAAGT
GATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGC
GCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAA
CTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGA
ACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATT
CACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCC
CACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAG
TGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCAT
CAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAA
TTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTC
CCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTA
CAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAAAGAGGCC
GCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATATAGGTAA
AACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACTCCTCAGA
TTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTGATTAAGT
GCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAACTGGCATC
TGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCAAGGAGGG
CATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGAGGTAAGA

>28983_28983_9_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000416672_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_10_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000420357_length(transcript)=1477nt_BP=265nt
AGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGG
CCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAGTTTTTAAACCAGTGTGAGCCACTGCCCCATGTTGTGTTGATGCCAATCT
GCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAAATGAAGT
GATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGC
GCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAA
CTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGA
ACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATT
CACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCC
CACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAG
TGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCAT
CAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAA
TTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTC
CCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTA
CAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAAAGAGGCC
GCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATATAGGTAA
AACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACTCCTCAGA

>28983_28983_10_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000420357_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_11_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000449677_length(transcript)=1939nt_BP=265nt
AGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGG
CCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAGTTTTTAAACCAGTGTGAGCCACTGCCCCATGTTGTGTTGATGCCAATCT
GCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAAATGAAGT
GATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGC
GCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAA
CTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGA
ACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATT
CACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCC
CACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAG
TGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCAT
CAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAA
TTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTC
CCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTA
CAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAAAGAGGCC
GCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATATAGGTAA
AACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACTCCTCAGA
TTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTGATTAAGT
GCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAACTGGCATC
TGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCAAGGAGGG
CATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGAGGTAAGA
CAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTTCTTCCTCTTCCTTACC

>28983_28983_11_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000449677_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_12_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000453357_length(transcript)=5291nt_BP=265nt
AGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTGGAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGG
CCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAGTTTTTAAACCAGTGTGAGCCACTGCCCCATGTTGTGTTGATGCCAATCT
GCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAAATGAAGT
GATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGC
GCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAA
CTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGA
ACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATT
CACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCC
CACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAG
TGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCAT
CAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAA
TTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTC
CCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTA
CAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAAAGAGGCC
GCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATATAGGTAA
AACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACTCCTCAGA
TTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTGATTAAGT
GCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAACTGGCATC
TGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCAAGGAGGG
CATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGAGGTAAGA
CAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTTCTTCCTCTTCCTTACC
CCTTGCAGTAGGGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGTTTTTTCTAACACAACAAAGTGGGACCATCTCTA
TTCCCATCTAAGCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGGATATGGGGACAGGAGAGATTAAAGCAGGTTCAA
AAACACATGAACTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACACGTGTTGATCTAGTTATCTAACATTGTTGTTATA
AGAAAATGAGTTTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGGGTACTGTGTCATCACAAAATCTCTCAGTAAGGC
TATATGTGATCCTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAATGATATCTGAGTAAATAGACTTGAGGAATCCTCT
ACCACAGTGTCCCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTATTCAGCCTCCCTGAATATGCTTTCTCTATAGAAC
CACTAACATATGGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATATTGTGGAAGATTGAAATCCACAGATAATTCATG
ACCCTCATCTTATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAGATGTCCTGGTAGACTAAAGGTGAACAGATTTGC
TCTTGCTCATCTTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAAGTCAAGGACCCAGATGAACCACAAGGCAGCTAG
TCAGCTACTTAGAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGGTGGGGAGTTGGGGAGTACTTGGCAGTTGGGATA
TGATCCATTTTTTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAATGTTGTGAATCTCCATGCCAAGTGAAAAAGGCCT
AAAGATGAGTTGAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTGTTGGCCATTTTCTCTAACTAACATGTGGTATGT
ATGGTCCCCTATATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCTTTTCTCAGGAACCAAAGGCTTATGATGTAGGAC
AAAGAAATCATCTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGGAAAACACCCTTTTGCTAGTGTGCTTAACTTATT
TATTTCTTCTAGGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCACTGATAGAATTTCTGAAAGAGAAAGAGAAGTAG
ATGGTCAACCAGTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCATTCACTATTGAGTAAAAACTTGTAGAAAGCACAT
TATAGAGCTTATGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGCATTTTCCCTCTTCCCTTCTAATGGGCATTATAA
TTGTTTCATCTACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACATTTTAAGTATTTTTAAATAGATGAAAATTCTAAA
TGATTTTCCCTCAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAATCCCTGAATGTCTGGAGTTACCTCCCATGGATTT
TTTTTTCCTTTGGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAACAAAGGAGGAAGTTAACTTAATTCACCTCAGAC
TTCAGCCTAAGATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGTTTCTTTTACTTATTGCTGCTAGGATCCTACATA
GGATTTCTATAGAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGTATGTTACAATACAATTTCAAAGAGAACCCACAT
TTGTGAGATTTACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAAAAGTGAGCTTACACTTGAACTTAGTTATTCACT
GTGACCTAAATTTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCTTGAAAGAGATTTACTCATCTATCCAAGCACTTA
ATTTGGAAATTTTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAGTACTTGGTAAGTTACTTAAAATTTTTACAAAAA
TATCCCACTCAATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCATGCTTTAAATATGGCTTTAAATTATGCCACCAAA
ATGGTGCACTTCACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTTTACAACATTGCTTCTACATTCTTACTGGTTTAC
ATTAAAATCCTTTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCATTTACCAGTGCAGGAAGTCTCATAAAACTCAGA
TGTACTCCCACAAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACACAGTTCTCTTTAAAGAGAAGAACTTTTTTATTAT
TATTTTTATCTCCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTTCAGTTGTCTTTGGGAGGGGATGTTAAGTCAAAT
CACTAAAACAGGGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCCTTGAGAAACATTCTCAGCATCAGGATTGATAAA
CAAATGTAGATGATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAAACTTCTGGCAAATTTACCTGTGAATTTCAAAAT
GTTATAAAATCTCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATTTCTTAGTCCCTCTGCCCTCTGTAAATGTGTTGA
GTGATATAGCTATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAGCTCTGTAAAGGTCACAGGAATCGTGAAGGAGCT
GAGAAATCTTCCTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGAAACATTGCAGAGTTTGAATCCTCAGTAACTCTC
ATTGACTGGATTAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTACAGAGAATGACACAATTTTATTCGCCTTTGGTGT
TAGTTGCCATAGTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCACCGTTTCCGTAGTTTCCACTGTTTTGTCTGCAT

>28983_28983_12_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000577682_UNC5D_chr8_35608100_ENST00000453357_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_13_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000287272_length(transcript)=7276nt_BP=362nt
AAAGGGCCCAGGCGCTACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTG
GAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAG
TTTTTAAACCAGGAATATCACAGGAGTGATGCTGTGTTCTTCACTGCATGATTTCAAAAGTGTGAGCCACTGCCCCATGTTGTGTTGATG
CCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAA
ATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGA
CCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGG
ATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCC
TGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTA
AACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTT
ATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCC
TAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCT
ACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCA
ACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATC
TTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACT
TCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAA
AGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATA
TAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACT
CCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTG
ATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAAC
TGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCA
AGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGA
GGTAAGACAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTTCTTCCTCTT
CCTTACCCCTTGCAGTAGGGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGTTTTTTCTAACACAACAAAGTGGGACC
ATCTCTATTCCCATCTAAGCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGGATATGGGGACAGGAGAGATTAAAGCA
GGTTCAAAAACACATGAACTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACACGTGTTGATCTAGTTATCTAACATTGT
TGTTATAAGAAAATGAGTTTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGGGTACTGTGTCATCACAAAATCTCTCA
GTAAGGCTATATGTGATCCTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAATGATATCTGAGTAAATAGACTTGAGGA
ATCCTCTACCACAGTGTCCCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTATTCAGCCTCCCTGAATATGCTTTCTCT
ATAGAACCACTAACATATGGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATATTGTGGAAGATTGAAATCCACAGATA
ATTCATGACCCTCATCTTATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAGATGTCCTGGTAGACTAAAGGTGAACA
GATTTGCTCTTGCTCATCTTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAAGTCAAGGACCCAGATGAACCACAAGG
CAGCTAGTCAGCTACTTAGAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGGTGGGGAGTTGGGGAGTACTTGGCAGT
TGGGATATGATCCATTTTTTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAATGTTGTGAATCTCCATGCCAAGTGAAA
AAGGCCTAAAGATGAGTTGAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTGTTGGCCATTTTCTCTAACTAACATGT
GGTATGTATGGTCCCCTATATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCTTTTCTCAGGAACCAAAGGCTTATGAT
GTAGGACAAAGAAATCATCTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGGAAAACACCCTTTTGCTAGTGTGCTTA
ACTTATTTATTTCTTCTAGGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCACTGATAGAATTTCTGAAAGAGAAAGA
GAAGTAGATGGTCAACCAGTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCATTCACTATTGAGTAAAAACTTGTAGAA
AGCACATTATAGAGCTTATGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGCATTTTCCCTCTTCCCTTCTAATGGGC
ATTATAATTGTTTCATCTACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACATTTTAAGTATTTTTAAATAGATGAAAA
TTCTAAATGATTTTCCCTCAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAATCCCTGAATGTCTGGAGTTACCTCCCA
TGGATTTTTTTTTCCTTTGGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAACAAAGGAGGAAGTTAACTTAATTCAC
CTCAGACTTCAGCCTAAGATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGTTTCTTTTACTTATTGCTGCTAGGATC
CTACATAGGATTTCTATAGAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGTATGTTACAATACAATTTCAAAGAGAA
CCCACATTTGTGAGATTTACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAAAAGTGAGCTTACACTTGAACTTAGTT
ATTCACTGTGACCTAAATTTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCTTGAAAGAGATTTACTCATCTATCCAA
GCACTTAATTTGGAAATTTTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAGTACTTGGTAAGTTACTTAAAATTTTT
ACAAAAATATCCCACTCAATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCATGCTTTAAATATGGCTTTAAATTATGC
CACCAAAATGGTGCACTTCACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTTTACAACATTGCTTCTACATTCTTACT
GGTTTACATTAAAATCCTTTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCATTTACCAGTGCAGGAAGTCTCATAAA
ACTCAGATGTACTCCCACAAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACACAGTTCTCTTTAAAGAGAAGAACTTTT
TTATTATTATTTTTATCTCCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTTCAGTTGTCTTTGGGAGGGGATGTTAA
GTCAAATCACTAAAACAGGGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCCTTGAGAAACATTCTCAGCATCAGGAT
TGATAAACAAATGTAGATGATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAAACTTCTGGCAAATTTACCTGTGAATT
TCAAAATGTTATAAAATCTCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATTTCTTAGTCCCTCTGCCCTCTGTAAAT
GTGTTGAGTGATATAGCTATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAGCTCTGTAAAGGTCACAGGAATCGTGA
AGGAGCTGAGAAATCTTCCTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGAAACATTGCAGAGTTTGAATCCTCAGT
AACTCTCATTGACTGGATTAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTACAGAGAATGACACAATTTTATTCGCCT
TTGGTGTTAGTTGCCATAGTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCACCGTTTCCGTAGTTTCCACTGTTTTG
TCTGCATAGAATTTTCCTGAACTACAAGCAAAAATGTATTTTGTCCAATGTCACAAAAGTGAAAATGTTACTAATCTTAGATGTGTTGCA
TATTTTGTGTTTTTACGTTCCAAACTCTTTCAAAAGCTGCCGTTACAAAGCTGTTTGGCTGTATTGACAGCATGTGGTGTTTTTACAAAA
GCAATTCTAGGAGAGCCAGTGTCTACCATGAACTCCTGACATCCCCACTCCAGGGTCATTCATGACATTGAAATGGCAACTTGTACACTG
TAATTCTTCGAAAAGTAACAGGGGATGGAAATCAGACCTGGCCGTTAGTCACTAGTGTGTAGTACCGTGATCTGAAGTAGGAAATTTAAC
TGACATAGAATAATTGTGGTTTTTGAAGCAGCTACTCATTGCTTTTTCCTTTTGCTGTGAAGATCATGGATTGGGAATGTCCTCGTGAGG
TGGACCTAAGGCAGTAACATTTAAACTTCATGTCCTAGCACCCGCCCTCCATCTGACCCAAAGATAAAAAAGGCATCAAGCTTCATGGTT
ATGCCTAAGCTTAAAAATTCCCTTCCCCACTACTAATATTGAGTTCAGCAGGGCCCCATCTTACTTATTTTTCAAAAAAGTTATAGCTTT
GAATTATAGACTATATTACTAAATTTGGTAAGGTAGTTCTTTGCATGAATGGGAATGTGTGTCAAAATACTTTCACAAAAGGCATGATTA
CAATGGAAATGCCCCTTTGCCTCCAGTTTTGCTAACCCTAAAAAGTATTTCACTAATTTCAAGCACTGTTTACACTCAAATCCCAAAATT
GGCCAAATTATATAATTCTCTTAAATTTTCATTTCTGTAGGTGGAGATTTAACTATGGTTCTGGTGAATCATAGAAGGGAGAGACAATAT
TTGAGGGGAGTTTATCAGCAGAATATCATGCCTTATGACCCCATTACTGAAACACAGACATTACAATCAGAAATAGACCTAATAATTCCA
ATATCCCTCCATTAACTAGTTCCAGTGATGCTGAGAGACACAGCACCCTGTGCCAGGTATCAGAAATATAAGCCTCAGCAGAGGGTAACT
GAAAACTTTCAATCAGAAACACTCTCCAAGGCTTATGGCTAGATTATGTAGGTCACTACCATTCAAAACTTTTCTATACAAAGGTGGAAA
AGCACTCAGAATCTGGGAATTTTCTGGTTGGAAGAACAATGTTCTCCTTTTCCAAATTGGAATAAAGACTCAGAATTACCCATTCTTCAT
AATCATGTCTGATTGGTACATACACTCCAGGAAGTCTCAACCTAGAAACATTTCCAACCTAAGCATTTAAAGGAAAACTGGCTCATTCTT
CTGACCCAAACTCAAAAAATATGAGTACTTGCGTACCTCCATTTCTGCATGAAGATTTTAAAACAGATTTCATTTTTTTCTGTTTATTTT
GGGAAGGTGCGTGGGGGTGTTCTTTCAAGTGATTCACATCTCAAACCCATACCACTCTCAACTTTTATTTGATGTGTTCAAAGCCAAAAA
ATAAAATAAAATAAAGCAGGGCTGAACACTTAATTTGACATGAAGCTGAAGGACTGAGCAAGCCAGAGGAGAGAGGTTGAATGAAGCATA
GCCTTGGCTTCATACCACACTTTTTGTGCCTTGTATTATCAATGTAAATTCTGAATGTTGTACAGTAAACTTGGATGGACTTCTTAGAAA
AGGCTGCACTGGCTTCTTTTTCAGCACATGTACATATCTATAAATATATATACATATATATTTGGTAATGCCAAACAGCTCTGTTATATT
GTATTGAACAAAATGGACGGTTTGGATGTTTTATGTCGAGTTTGCAAAAAAAAAAAAAAAAAAAAAAACTGGATGGTTGCAGACTTTTCA

>28983_28983_13_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000287272_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_14_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000404895_length(transcript)=1351nt_BP=362nt
AAAGGGCCCAGGCGCTACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTG
GAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAG
TTTTTAAACCAGGAATATCACAGGAGTGATGCTGTGTTCTTCACTGCATGATTTCAAAAGTGTGAGCCACTGCCCCATGTTGTGTTGATG
CCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAA
ATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGA
CCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGG
ATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCC
TGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTA
AACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTT
ATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCC
TAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCT
ACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCA
ACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATC
TTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACT
TCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAA

>28983_28983_14_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000404895_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_15_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000416672_length(transcript)=1934nt_BP=362nt
AAAGGGCCCAGGCGCTACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTG
GAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAG
TTTTTAAACCAGGAATATCACAGGAGTGATGCTGTGTTCTTCACTGCATGATTTCAAAAGTGTGAGCCACTGCCCCATGTTGTGTTGATG
CCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAA
ATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGA
CCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGG
ATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCC
TGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTA
AACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTT
ATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCC
TAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCT
ACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCA
ACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATC
TTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACT
TCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAA
AGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATA
TAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACT
CCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTG
ATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAAC
TGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCA
AGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGA

>28983_28983_15_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000416672_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_16_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000420357_length(transcript)=1574nt_BP=362nt
AAAGGGCCCAGGCGCTACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTG
GAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAG
TTTTTAAACCAGGAATATCACAGGAGTGATGCTGTGTTCTTCACTGCATGATTTCAAAAGTGTGAGCCACTGCCCCATGTTGTGTTGATG
CCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAA
ATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGA
CCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGG
ATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCC
TGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTA
AACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTT
ATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCC
TAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCT
ACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCA
ACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATC
TTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACT
TCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAA
AGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATA
TAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACT

>28983_28983_16_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000420357_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_17_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000449677_length(transcript)=2036nt_BP=362nt
AAAGGGCCCAGGCGCTACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTG
GAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAG
TTTTTAAACCAGGAATATCACAGGAGTGATGCTGTGTTCTTCACTGCATGATTTCAAAAGTGTGAGCCACTGCCCCATGTTGTGTTGATG
CCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAA
ATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGA
CCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGG
ATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCC
TGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTA
AACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTT
ATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCC
TAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCT
ACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCA
ACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATC
TTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACT
TCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAA
AGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATA
TAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACT
CCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTG
ATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAAC
TGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCA
AGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGA
GGTAAGACAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTTCTTCCTCTT

>28983_28983_17_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000449677_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

--------------------------------------------------------------
>28983_28983_18_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000453357_length(transcript)=5388nt_BP=362nt
AAAGGGCCCAGGCGCTACACGCTGCGCAGGCGCAGGAGCGGCTCCGGGTAGTCCCCACAGCTGCGCCGGTGACTGAGGGGCCGGGCAGTG
GAGAAGTGGTGGCGGCGGGCGGCGGGCGGCAAAGGAGCAGCCATGAGGGCCGGGCCCAGTCACCGACCGTGCTGAGGAGTCATGGAAGAG
TTTTTAAACCAGGAATATCACAGGAGTGATGCTGTGTTCTTCACTGCATGATTTCAAAAGTGTGAGCCACTGCCCCATGTTGTGTTGATG
CCAATCTGCCATGCTAGCCTGTCTACCAGGGCCAGGTGACCTGTCCTTTCAGCTTCTTTCTCACACGCAGATGAACACTGGACTTCAGAA
ATGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGA
CCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGG
ATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCC
TGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTA
AACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTT
ATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCC
TAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCT
ACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCA
ACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATC
TTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACT
TCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAA
AGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATA
TAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACT
CCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTG
ATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAAC
TGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCA
AGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGA
GGTAAGACAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTTCTTCCTCTT
CCTTACCCCTTGCAGTAGGGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGTTTTTTCTAACACAACAAAGTGGGACC
ATCTCTATTCCCATCTAAGCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGGATATGGGGACAGGAGAGATTAAAGCA
GGTTCAAAAACACATGAACTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACACGTGTTGATCTAGTTATCTAACATTGT
TGTTATAAGAAAATGAGTTTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGGGTACTGTGTCATCACAAAATCTCTCA
GTAAGGCTATATGTGATCCTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAATGATATCTGAGTAAATAGACTTGAGGA
ATCCTCTACCACAGTGTCCCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTATTCAGCCTCCCTGAATATGCTTTCTCT
ATAGAACCACTAACATATGGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATATTGTGGAAGATTGAAATCCACAGATA
ATTCATGACCCTCATCTTATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAGATGTCCTGGTAGACTAAAGGTGAACA
GATTTGCTCTTGCTCATCTTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAAGTCAAGGACCCAGATGAACCACAAGG
CAGCTAGTCAGCTACTTAGAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGGTGGGGAGTTGGGGAGTACTTGGCAGT
TGGGATATGATCCATTTTTTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAATGTTGTGAATCTCCATGCCAAGTGAAA
AAGGCCTAAAGATGAGTTGAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTGTTGGCCATTTTCTCTAACTAACATGT
GGTATGTATGGTCCCCTATATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCTTTTCTCAGGAACCAAAGGCTTATGAT
GTAGGACAAAGAAATCATCTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGGAAAACACCCTTTTGCTAGTGTGCTTA
ACTTATTTATTTCTTCTAGGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCACTGATAGAATTTCTGAAAGAGAAAGA
GAAGTAGATGGTCAACCAGTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCATTCACTATTGAGTAAAAACTTGTAGAA
AGCACATTATAGAGCTTATGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGCATTTTCCCTCTTCCCTTCTAATGGGC
ATTATAATTGTTTCATCTACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACATTTTAAGTATTTTTAAATAGATGAAAA
TTCTAAATGATTTTCCCTCAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAATCCCTGAATGTCTGGAGTTACCTCCCA
TGGATTTTTTTTTCCTTTGGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAACAAAGGAGGAAGTTAACTTAATTCAC
CTCAGACTTCAGCCTAAGATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGTTTCTTTTACTTATTGCTGCTAGGATC
CTACATAGGATTTCTATAGAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGTATGTTACAATACAATTTCAAAGAGAA
CCCACATTTGTGAGATTTACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAAAAGTGAGCTTACACTTGAACTTAGTT
ATTCACTGTGACCTAAATTTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCTTGAAAGAGATTTACTCATCTATCCAA
GCACTTAATTTGGAAATTTTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAGTACTTGGTAAGTTACTTAAAATTTTT
ACAAAAATATCCCACTCAATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCATGCTTTAAATATGGCTTTAAATTATGC
CACCAAAATGGTGCACTTCACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTTTACAACATTGCTTCTACATTCTTACT
GGTTTACATTAAAATCCTTTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCATTTACCAGTGCAGGAAGTCTCATAAA
ACTCAGATGTACTCCCACAAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACACAGTTCTCTTTAAAGAGAAGAACTTTT
TTATTATTATTTTTATCTCCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTTCAGTTGTCTTTGGGAGGGGATGTTAA
GTCAAATCACTAAAACAGGGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCCTTGAGAAACATTCTCAGCATCAGGAT
TGATAAACAAATGTAGATGATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAAACTTCTGGCAAATTTACCTGTGAATT
TCAAAATGTTATAAAATCTCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATTTCTTAGTCCCTCTGCCCTCTGTAAAT
GTGTTGAGTGATATAGCTATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAGCTCTGTAAAGGTCACAGGAATCGTGA
AGGAGCTGAGAAATCTTCCTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGAAACATTGCAGAGTTTGAATCCTCAGT
AACTCTCATTGACTGGATTAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTACAGAGAATGACACAATTTTATTCGCCT
TTGGTGTTAGTTGCCATAGTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCACCGTTTCCGTAGTTTCCACTGTTTTG

>28983_28983_18_FAM222B-UNC5D_FAM222B_chr17_27093604_ENST00000583522_UNC5D_chr8_35608100_ENST00000453357_length(amino acids)=313AA_BP=5
MDFRNEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQ
GGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQV
QTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQ

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Fusion Gene PPI Analysis for FAM222B-UNC5D


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAM222B-UNC5D


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAM222B-UNC5D


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource