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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:FAM49B-GNAL (FusionGDB2 ID:29067) |
Fusion Gene Summary for FAM49B-GNAL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FAM49B-GNAL | Fusion gene ID: 29067 | Hgene | Tgene | Gene symbol | FAM49B | GNAL | Gene ID | 51571 | 2774 |
| Gene name | CYFIP related Rac1 interactor B | G protein subunit alpha L | |
| Synonyms | BM-009|CYRI|CYRI-B|FAM49B|L1 | DYT25 | |
| Cytomap | 8q24.21 | 18p11.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein FAM49BFAM49B/JPH1 fusionMTSS1/FAM49B fusionfamily with sequence similarity 49 member B | guanine nucleotide-binding protein G(olf) subunit alphaadenylate cyclase-stimulating G alpha protein, olfactory typeguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory typeguanine nucleotide binding protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | P38405 | |
| Ensembl transtripts involved in fusion gene | ENST00000401979, ENST00000517654, ENST00000519110, ENST00000519540, ENST00000519824, ENST00000522746, ENST00000523509, ENST00000522250, ENST00000522941, ENST00000518879, | ENST00000602628, ENST00000590972, ENST00000269162, ENST00000334049, ENST00000423027, ENST00000535121, | |
| Fusion gene scores | * DoF score | 30 X 20 X 14=8400 | 11 X 10 X 6=660 |
| # samples | 37 | 12 | |
| ** MAII score | log2(37/8400*10)=-4.50479215203717 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/660*10)=-2.4594316186373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FAM49B [Title/Abstract] AND GNAL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | FAM49B(130883621)-GNAL(11862394), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | FAM49B-GNAL seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across FAM49B (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GNAL (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | COAD | TCGA-DM-A1D6-01A | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
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Fusion Gene ORF analysis for FAM49B-GNAL |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000401979 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-5UTR | ENST00000517654 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-5UTR | ENST00000519110 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-5UTR | ENST00000519540 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-5UTR | ENST00000519824 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-5UTR | ENST00000522746 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-5UTR | ENST00000523509 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-intron | ENST00000401979 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-intron | ENST00000517654 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-intron | ENST00000519110 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-intron | ENST00000519540 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-intron | ENST00000519824 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-intron | ENST00000522746 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5CDS-intron | ENST00000523509 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522250 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522250 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522250 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522250 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522941 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522941 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522941 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-3CDS | ENST00000522941 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-5UTR | ENST00000522250 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-5UTR | ENST00000522941 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-intron | ENST00000522250 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| 5UTR-intron | ENST00000522941 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000401979 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000401979 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000401979 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000401979 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000517654 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000517654 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000517654 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000517654 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000519110 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000519110 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000519110 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000519110 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000522746 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000522746 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000522746 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000522746 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000523509 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000523509 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000523509 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| Frame-shift | ENST00000523509 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519540 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519540 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519540 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519540 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519824 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519824 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519824 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| In-frame | ENST00000519824 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| intron-3CDS | ENST00000518879 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| intron-3CDS | ENST00000518879 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| intron-3CDS | ENST00000518879 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| intron-3CDS | ENST00000518879 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| intron-5UTR | ENST00000518879 | ENST00000602628 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| intron-intron | ENST00000518879 | ENST00000590972 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000519824 | FAM49B | chr8 | 130883621 | - | ENST00000334049 | GNAL | chr18 | 11862394 | + | 5674 | 469 | 407 | 1123 | 238 |
| ENST00000519824 | FAM49B | chr8 | 130883621 | - | ENST00000535121 | GNAL | chr18 | 11862394 | + | 1124 | 469 | 407 | 1123 | 239 |
| ENST00000519824 | FAM49B | chr8 | 130883621 | - | ENST00000269162 | GNAL | chr18 | 11862394 | + | 1399 | 469 | 407 | 1123 | 238 |
| ENST00000519824 | FAM49B | chr8 | 130883621 | - | ENST00000423027 | GNAL | chr18 | 11862394 | + | 1912 | 469 | 407 | 1123 | 238 |
| ENST00000519540 | FAM49B | chr8 | 130883621 | - | ENST00000334049 | GNAL | chr18 | 11862394 | + | 5801 | 596 | 534 | 1250 | 238 |
| ENST00000519540 | FAM49B | chr8 | 130883621 | - | ENST00000535121 | GNAL | chr18 | 11862394 | + | 1251 | 596 | 534 | 1250 | 238 |
| ENST00000519540 | FAM49B | chr8 | 130883621 | - | ENST00000269162 | GNAL | chr18 | 11862394 | + | 1526 | 596 | 534 | 1250 | 238 |
| ENST00000519540 | FAM49B | chr8 | 130883621 | - | ENST00000423027 | GNAL | chr18 | 11862394 | + | 2039 | 596 | 534 | 1250 | 238 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000519824 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.001707169 | 0.99829286 |
| ENST00000519824 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.004835425 | 0.9951645 |
| ENST00000519824 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.004619095 | 0.9953809 |
| ENST00000519824 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.005587676 | 0.99441236 |
| ENST00000519540 | ENST00000334049 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.001808773 | 0.9981912 |
| ENST00000519540 | ENST00000535121 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.004315631 | 0.9956844 |
| ENST00000519540 | ENST00000269162 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.003886607 | 0.9961134 |
| ENST00000519540 | ENST00000423027 | FAM49B | chr8 | 130883621 | - | GNAL | chr18 | 11862394 | + | 0.005965082 | 0.99403495 |
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Fusion Genomic Features for FAM49B-GNAL |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FAM49B | chr8 | 130883620 | - | GNAL | chr18 | 11862393 | + | 5.53E-08 | 1 |
| FAM49B | chr8 | 130883620 | - | GNAL | chr18 | 11862393 | + | 5.53E-08 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for FAM49B-GNAL |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:130883621/chr18:11862394) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | GNAL |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 41_381 | 0 | 175.0 | Domain | G-alpha | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 185_191 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 210_214 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 279_282 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 279_282 | 240 | 459.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 185_191 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 210_214 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 279_282 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 185_191 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 210_214 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 279_282 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 185_191 | 0 | 175.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 210_214 | 0 | 175.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 279_282 | 0 | 175.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 49_56 | 0 | 175.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 183_191 | 163 | 382.0 | Region | G2 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 206_215 | 163 | 382.0 | Region | G3 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 275_282 | 163 | 382.0 | Region | G4 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 351_356 | 163 | 382.0 | Region | G5 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 275_282 | 240 | 459.0 | Region | G4 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 351_356 | 240 | 459.0 | Region | G5 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 183_191 | 163 | 382.0 | Region | G2 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 206_215 | 163 | 382.0 | Region | G3 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 275_282 | 163 | 382.0 | Region | G4 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 351_356 | 163 | 382.0 | Region | G5 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 183_191 | 163 | 382.0 | Region | G2 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 206_215 | 163 | 382.0 | Region | G3 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 275_282 | 163 | 382.0 | Region | G4 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 351_356 | 163 | 382.0 | Region | G5 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 183_191 | 0 | 175.0 | Region | G2 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 206_215 | 0 | 175.0 | Region | G3 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 275_282 | 0 | 175.0 | Region | G4 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 351_356 | 0 | 175.0 | Region | G5 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000602628 | 0 | 8 | 44_57 | 0 | 175.0 | Region | G1 motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 41_381 | 163 | 382.0 | Domain | G-alpha | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 41_381 | 240 | 459.0 | Domain | G-alpha | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 41_381 | 163 | 382.0 | Domain | G-alpha | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 41_381 | 163 | 382.0 | Domain | G-alpha | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 49_56 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 185_191 | 240 | 459.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 210_214 | 240 | 459.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 49_56 | 240 | 459.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 49_56 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 49_56 | 163 | 382.0 | Nucleotide binding | GTP | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000269162 | 5 | 13 | 44_57 | 163 | 382.0 | Region | G1 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 183_191 | 240 | 459.0 | Region | G2 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 206_215 | 240 | 459.0 | Region | G3 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000334049 | 4 | 12 | 44_57 | 240 | 459.0 | Region | G1 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000423027 | 4 | 12 | 44_57 | 163 | 382.0 | Region | G1 motif | |
| Tgene | GNAL | chr8:130883621 | chr18:11862394 | ENST00000535121 | 5 | 13 | 44_57 | 163 | 382.0 | Region | G1 motif |
Top |
Fusion Gene Sequence for FAM49B-GNAL |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >29067_29067_1_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000269162_length(transcript)=1526nt_BP=596nt CGGCGCCCTCACTTCCTGGCATTCCCTCCTCCCCCTCCCCGTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCC GCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGAGGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTC CCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGAGGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGGTAAT TCATTTGCACACCTGTTAGCAAGAAACAGAAGTTGAAGGACTGGAACAAGTGAACTAGGAAAGAGGGAACGCCAATCCAAGGATAGAAGG ACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCTTAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGC CAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTACAGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAG AAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGCTGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTT GACTACACACCCACAGACCAGGACCTCCTCAGATGCAGAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAAC TTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGAGGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCA GCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATAACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAAC AACAGGTGGTTACGGACCATTTCTATCATCTTGTTCTTGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATT GAAGACTATTTCCCAGAATATGCAAATTATACTGTTCCTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAG TTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGGCCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGAC ACAGAGAACATCCGCAGGGTGTTCAACGACTGCCGCGACATCATCCAGCGGATGCACCTCAAGCAGTATGAGCTCTTGTGAGGATGCTGC CGCCACCCTGCGACGGAGCGGCGCCCCGGACTGCCTGACTGCCAGCCCCATGCCATGGTAGGAGGCAGAGTCTCTAGTTCCATCTCGCTG CCGTCTGTCCCGTTCTGTGTCGACCACCAAGCCTCTGGCTACCTCTGTCCCCTCAGGTTTGGTTGTGTAGCTTCTGTTGTCATTGAATAC >29067_29067_1_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000269162_length(amino acids)=238AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- >29067_29067_2_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000334049_length(transcript)=5801nt_BP=596nt CGGCGCCCTCACTTCCTGGCATTCCCTCCTCCCCCTCCCCGTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCC GCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGAGGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTC CCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGAGGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGGTAAT TCATTTGCACACCTGTTAGCAAGAAACAGAAGTTGAAGGACTGGAACAAGTGAACTAGGAAAGAGGGAACGCCAATCCAAGGATAGAAGG ACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCTTAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGC CAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTACAGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAG AAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGCTGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTT GACTACACACCCACAGACCAGGACCTCCTCAGATGCAGAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAAC TTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGAGGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCA GCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATAACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAAC AACAGGTGGTTACGGACCATTTCTATCATCTTGTTCTTGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATT GAAGACTATTTCCCAGAATATGCAAATTATACTGTTCCTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAG TTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGGCCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGAC ACAGAGAACATCCGCAGGGTGTTCAACGACTGCCGCGACATCATCCAGCGGATGCACCTCAAGCAGTATGAGCTCTTGTGAGGATGCTGC CGCCACCCTGCGACGGAGCGGCGCCCCGGACTGCCTGACTGCCAGCCCCATGCCATGGTAGGAGGCAGAGTCTCTAGTTCCATCTCGCTG CCGTCTGTCCCGTTCTGTGTCGACCACCAAGCCTCTGGCTACCTCTGTCCCCTCAGGTTTGGTTGTGTAGCTTCTGTTGTCATTGAATAC GGCCTCCCGCAGCATCCCACCCCCAAACCACCGACTCTCATTGCCGACACTGCAGCAGAATCTCTCCGGGTGGGAGCCCCATTATTCATT CTCCCTTTATTGATTCATCGAGGAGAACTTGGTAGATGGGGAGAAAACACAGTTGGTTTTTTTTTCCACGTTATCAACCGTGACTGCAAG AGCGTTCGTGCAGTGCCCTGAGCCACGGCCGTCTCTGATTCTCCCTTTATGAAGCTGCAGGCTGACGAGAGATGGTCCCTTCCCATTGGC CTTAGCCCAAGACTTGGAGTCGACCCCAAGCGACAGAGTGACCAGAAACCCTTTTACAGTCACATTCAGAGTCGCTGCTGGCCTCAGGCA TTTGAATTAGAGCTACTTTGAGCCTCTTAGGCAGAAAACCTACCACATTCACTACTGCAAAATGTGTCCTGTCTAAAAATGATTCTCTAA ACTTTCCCTATACTTAGGCATAGTCTTCTTTCTTAGATTCTCTTTGTTGTTGTCCCTATTGCTGGTTTATTACACTGTACAGACCACAAA ATGTAATATTCTTTTGTATAACTACTAAAGAAAAATCCTTGTAGATCTTTGTGCCTTCACCATGGCTATCTATACCTGTACATGAAATGT GTTTGTATTGTGCTGAAGAGCTTAATGTCAACATTACCTGCTGCTTACTCTGAAAAAAGGAATGAATGGTAGCTGTAGAATTTAGGATAT TTTATCAGGTTGGCACTTTATAAAATACTCCCTGATTTAAAAAATTGTAAGTTATACACGTTAATCATCCACATTCTATCGACAATGTAC CAACATCACAAGCTGTTGCAACCACCTGCTGTTACTTCTCTGAGCTGTAAAAACCTGAACTCAATTCAGGGGTACAAATTGCAATCTAAT CTTTTCAGGGAACCAGGGATTTTTTTCTCTCTCTCTAGACAATATGTTTCCTCATTAGTCTGCTAATGAAACACTTCTTCAAGTTCCCCA AGTGGGAACAGGTCCATCATTCCCTTAGTCAAAACTTTGGACACAGGCTACGTCATACAAGTAAGCAAACAGTAAGAGAAAAACAAAATG TGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGCCAGGAGATCAAGACCATCCT GGCTAACATGGCGAAACCCTGTCTCTACCAAAAATACAAAAATTAGCCAGGCGTGGTGGCGGGCACCTGTAATCTCAGCTACTCGAGAGG CTGAGGCAGGAGAATCTCTTGAACCTGGGAGGTGGAGATTGCAGTGAGCCGAGGTCGTGCCATCGCACTCCAGCCTGGACATCAAAGTGA GACTCAGGCCAAAAAAAAAAAAAAAAAAAACCTTGACGTGTCAATGTTTGTGTCTGGCCTAGGAGAATGAGGATGACAGCTTCACTTGCC TTTTGAAGAAGAAACATTACAAAACCTTAATCTGAAGTATAAAGTCAAAAGATACGGCTCTTTCTCACACTTGCAAGACTTACAAATACA GCCTCAAACATTATGACACACCAACAATATCTAGAAAGTAAGAACTGGTGTAGCAATGATGCTTCATATTCTAGCTGTAGCCACAGAGTT GAGGGTAGTTTTTGTAGGTCTAAAATAATAATCTATAAAGATGTCCAAAGTTAAATTTTCAACAATACAAATCTAGAGAAGTGACAGCCT ACATTACTTCATTATTACTCTTCTTTTAGTCTTTAGTCTTTAATATTTTAAAGTTTACTCTATAAATCAGCATTTTGTAATCCTTTATAA ACTCATCCAGATTTAAATGCTACTTTTTCATGAAGAAAGGATAACTTTATAGACAGTCAGTGCAACACACACATTTTATCTCATCACCGT CTTACTGCCTCCCCATCCACTGTCTCATAAAGCCCTCAGCTGAACTAAGATAAATAATACAATGGAAATTATTTTCAGTTCCCCTTGCAC TGTCAAAGTAAAACAAGAAAACTGAAAAGCTGCACCCCCAGCAAGAAAGGGAAGTATGCTGTTGTATGCATCATTACTCAACAATTACCC TCTAACTAAACATCCTGTTTAAGAGTTTAATTCAAACAACAGCCAGACTGTTAAGAAAAAAAACAAAAAGAATAACTTTTATCTGGCTTA CAATTATTAAAGCATTTATTTTCAGGTACCAAAAGCCATATCCCATTCCACTTTTTAAGTTTCTTTTGATCACTGACAGGCATTAACAGA TGTAGCAACGTGGTCTCCTATAGAGAAAATTACACTTATCTAAAAATCTGATTCCATTAATTGATCAAGTATAAAAATCTACGAAAACAA TATGTTCTGCACATCACATCTGTACTTTTTTTTTTTTAAATATATTTTTTGAGACGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGT GGCATGATCTTGGCTCACTGCAACCTCCGCCTCCCGGGCTCAAGGGATTCTCCTGCCTCAGCCTCAGCTGGTATTATAGGCACTTGCTAC CATGCTTGGCTAATTTTTGTATTTCTAGCGGAGACGAGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCA CCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCCCGGCCACATCTGTACTTTTAAGGGTACAGCTTTACAGTA CATAGGAATTTGAGAACCACTTCACAGGAAGAGGGAAACAGCCCAATATTTATTTATGTATACACATAATCCCAAGTGTGTGCTGGGGCC ACCAGGCCCTTCCTGGGGGAACAAGGACTGTCGTGCATGTGAGTGACGACATTAATAGCATTTACATACTGTACAGATGCAACCTTTGAT GATACATATATTTGATAAAAATGAGAAAACAGATTTGTTGTAGAGTACCTGTCCACTTTTATAGCATGAGAACAGTACAATCAACTATTT ATTTTGCAGTTACTCATTTCAGTGATTGAGAATTTCTGTGCTGTGCAGAGAGACGGCCTGTAATTGGTCTCATCATCCACTTGATTCTAA CATGATCTCTGCCCAAAGTTCCATTTCTTGGGCTTTGATATTTATAATGGCGCCTGCTCTTCATCTTGTCTTACGCTTTCCGAGCAAGTT CAAACCAGAAAGAAAAGGTGAGGCTAGAAGCCCAAAGTGAGTGAGTGTGAGGACCACAAGGAAGCCCACCACTCCACAGTAGATGATCAA AACCACATCCTCACGTGGGAGGTAGCACTTGGAGAGGGTGTAGTCTGTGGGCGTGATGCTACCCTGGAAAGGAGAAGGGAAAGTTATGCT GAGAGCACCAGGCACACGTTGAACACCGCAGTCTTAGAAACAGCAGAGGGAAGACTGCCTTCTCAGGTCCCCCTCAGGTGAGGCAGGGAA CGGGCCCTCCTCACCTGAGACCAAGGGGGCCCAGCCTTCTCCCTGCACAGCTCACCCCCGACCAGCCCAGGCTCCAGCAGGAGAGACAAG TAAGGCCCAAGTGTGCCTGAGTGGAAAATGTCTGGGACACTGACCTGTCAAAACTGGCCCCTGGCTCACTGGGTTCCCATCAAATATAGT GGGGGATCCATAACAGAGATTCAGAGAGGCACCGTGGAGTTCCAGGGTCATCGGTCAGCGAGGAACAAGGAGGGAAAGGTGTCTTCCTGC CCCTTGATGCTCAACTAAGCATCTGTTCCCTAGAAATACATGTGTCCAGGTCGTCTCCATGGGCTTTTCTTTGCAGATACTTTTATGTGG AACAACAGTGGCAAATGTTTTCATTTACTTTGAATTTGAAAATGTTAGGGTTTCCTCCACCTTTTTATGAAGTAAAAGAACCTGTCGTAC CAGCATCATGAGCTGGATGCAGGAGCCCATGGCTGAAAGGAGTTAAAACGCCCAGTGGTCATTAAGTGAAACATCTTTTATCAACCTGCA AAAGCTGCAGCGTTCTCTGCCAGGTCAAATGGGCATGTTTAGAAAATAAGAGAAGATGGCTGAGTATAGCTAATGAATAAATGGTTGTTT CTTTAGAAAATTAAACACACACAGAGTGTAAGAGGAGAGGATACGGCCCTCCCTGAAGGATAAAGTCCACCTGGACGGTGCCCTGCCCTC GCTTCTCACATTAACTGCCCAGGAATGTCATGCTGATTGGTTCCCGGAAGGGTGTTTGGCAAGGGGCAGTGTATGGAGCTACGTGTAGAA GGAGAGAAATTTGTGTGTGGCTTTTGTAAATTTTGACCGATTGCAGCAATTAAATAGTTGATTACTGTGTTGATTTAAATACTTATGAAA >29067_29067_2_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000334049_length(amino acids)=238AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- >29067_29067_3_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000423027_length(transcript)=2039nt_BP=596nt CGGCGCCCTCACTTCCTGGCATTCCCTCCTCCCCCTCCCCGTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCC GCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGAGGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTC CCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGAGGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGGTAAT TCATTTGCACACCTGTTAGCAAGAAACAGAAGTTGAAGGACTGGAACAAGTGAACTAGGAAAGAGGGAACGCCAATCCAAGGATAGAAGG ACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCTTAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGC CAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTACAGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAG AAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGCTGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTT GACTACACACCCACAGACCAGGACCTCCTCAGATGCAGAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAAC TTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGAGGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCA GCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATAACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAAC AACAGGTGGTTACGGACCATTTCTATCATCTTGTTCTTGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATT GAAGACTATTTCCCAGAATATGCAAATTATACTGTTCCTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAG TTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGGCCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGAC ACAGAGAACATCCGCAGGGTGTTCAACGACTGCCGCGACATCATCCAGCGGATGCACCTCAAGCAGTATGAGCTCTTGTGAGGATGCTGC CGCCACCCTGCGACGGAGCGGCGCCCCGGACTGCCTGACTGCCAGCCCCATGCCATGGTAGGAGGCAGAGTCTCTAGTTCCATCTCGCTG CCGTCTGTCCCGTTCTGTGTCGACCACCAAGCCTCTGGCTACCTCTGTCCCCTCAGGTTTGGTTGTGTAGCTTCTGTTGTCATTGAATAC GGCCTCCCGCAGCATCCCACCCCCAAACCACCGACTCTCATTGCCGACACTGCAGCAGAATCTCTCCGGGTGGGAGCCCCATTATTCATT CTCCCTTTATTGATTCATCGAGGAGAACTTGGTAGATGGGGAGAAAACACAGTTGGTTTTTTTTTCCACGTTATCAACCGTGACTGCAAG AGCGTTCGTGCAGTGCCCTGAGCCACGGCCGTCTCTGATTCTCCCTTTATGAAGCTGCAGGCTGACGAGAGATGGTCCCTTCCCATTGGC CTTAGCCCAAGACTTGGAGTCGACCCCAAGCGACAGAGTGACCAGAAACCCTTTTACAGTCACATTCAGAGTCGCTGCTGGCCTCAGGCA TTTGAATTAGAGCTACTTTGAGCCTCTTAGGCAGAAAACCTACCACATTCACTACTGCAAAATGTGTCCTGTCTAAAAATGATTCTCTAA ACTTTCCCTATACTTAGGCATAGTCTTCTTTCTTAGATTCTCTTTGTTGTTGTCCCTATTGCTGGTTTATTACACTGTACAGACCACAAA >29067_29067_3_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000423027_length(amino acids)=238AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- >29067_29067_4_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000535121_length(transcript)=1251nt_BP=596nt CGGCGCCCTCACTTCCTGGCATTCCCTCCTCCCCCTCCCCGTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCC GCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGAGGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTC CCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGAGGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGGTAAT TCATTTGCACACCTGTTAGCAAGAAACAGAAGTTGAAGGACTGGAACAAGTGAACTAGGAAAGAGGGAACGCCAATCCAAGGATAGAAGG ACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCTTAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGC CAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTACAGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAG AAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGCTGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTT GACTACACACCCACAGACCAGGACCTCCTCAGATGCAGAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAAC TTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGAGGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCA GCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATAACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAAC AACAGGTGGTTACGGACCATTTCTATCATCTTGTTCTTGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATT GAAGACTATTTCCCAGAATATGCAAATTATACTGTTCCTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAG TTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGGCCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGAC >29067_29067_4_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519540_GNAL_chr18_11862394_ENST00000535121_length(amino acids)=238AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- >29067_29067_5_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000269162_length(transcript)=1399nt_BP=469nt GTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCCGCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGA GGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTCCCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGA GGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGATAGAAGGACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCT TAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGCCAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTAC AGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAGAAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGC TGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTTGACTACACACCCACAGACCAGGACCTCCTCAGATGCA GAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAACTTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGA GGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCAGCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATA ACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAACAACAGGTGGTTACGGACCATTTCTATCATCTTGTTCT TGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATTGAAGACTATTTCCCAGAATATGCAAATTATACTGTTC CTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAGTTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGG CCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGACACAGAGAACATCCGCAGGGTGTTCAACGACTGCCGCG ACATCATCCAGCGGATGCACCTCAAGCAGTATGAGCTCTTGTGAGGATGCTGCCGCCACCCTGCGACGGAGCGGCGCCCCGGACTGCCTG ACTGCCAGCCCCATGCCATGGTAGGAGGCAGAGTCTCTAGTTCCATCTCGCTGCCGTCTGTCCCGTTCTGTGTCGACCACCAAGCCTCTG GCTACCTCTGTCCCCTCAGGTTTGGTTGTGTAGCTTCTGTTGTCATTGAATACGGCCTCCCGCAGCATCCCACCCCCAAACCACCGACTC >29067_29067_5_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000269162_length(amino acids)=238AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- >29067_29067_6_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000334049_length(transcript)=5674nt_BP=469nt GTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCCGCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGA GGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTCCCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGA GGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGATAGAAGGACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCT TAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGCCAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTAC AGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAGAAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGC TGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTTGACTACACACCCACAGACCAGGACCTCCTCAGATGCA GAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAACTTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGA GGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCAGCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATA ACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAACAACAGGTGGTTACGGACCATTTCTATCATCTTGTTCT TGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATTGAAGACTATTTCCCAGAATATGCAAATTATACTGTTC CTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAGTTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGG CCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGACACAGAGAACATCCGCAGGGTGTTCAACGACTGCCGCG ACATCATCCAGCGGATGCACCTCAAGCAGTATGAGCTCTTGTGAGGATGCTGCCGCCACCCTGCGACGGAGCGGCGCCCCGGACTGCCTG ACTGCCAGCCCCATGCCATGGTAGGAGGCAGAGTCTCTAGTTCCATCTCGCTGCCGTCTGTCCCGTTCTGTGTCGACCACCAAGCCTCTG GCTACCTCTGTCCCCTCAGGTTTGGTTGTGTAGCTTCTGTTGTCATTGAATACGGCCTCCCGCAGCATCCCACCCCCAAACCACCGACTC TCATTGCCGACACTGCAGCAGAATCTCTCCGGGTGGGAGCCCCATTATTCATTCTCCCTTTATTGATTCATCGAGGAGAACTTGGTAGAT GGGGAGAAAACACAGTTGGTTTTTTTTTCCACGTTATCAACCGTGACTGCAAGAGCGTTCGTGCAGTGCCCTGAGCCACGGCCGTCTCTG ATTCTCCCTTTATGAAGCTGCAGGCTGACGAGAGATGGTCCCTTCCCATTGGCCTTAGCCCAAGACTTGGAGTCGACCCCAAGCGACAGA GTGACCAGAAACCCTTTTACAGTCACATTCAGAGTCGCTGCTGGCCTCAGGCATTTGAATTAGAGCTACTTTGAGCCTCTTAGGCAGAAA ACCTACCACATTCACTACTGCAAAATGTGTCCTGTCTAAAAATGATTCTCTAAACTTTCCCTATACTTAGGCATAGTCTTCTTTCTTAGA TTCTCTTTGTTGTTGTCCCTATTGCTGGTTTATTACACTGTACAGACCACAAAATGTAATATTCTTTTGTATAACTACTAAAGAAAAATC CTTGTAGATCTTTGTGCCTTCACCATGGCTATCTATACCTGTACATGAAATGTGTTTGTATTGTGCTGAAGAGCTTAATGTCAACATTAC CTGCTGCTTACTCTGAAAAAAGGAATGAATGGTAGCTGTAGAATTTAGGATATTTTATCAGGTTGGCACTTTATAAAATACTCCCTGATT TAAAAAATTGTAAGTTATACACGTTAATCATCCACATTCTATCGACAATGTACCAACATCACAAGCTGTTGCAACCACCTGCTGTTACTT CTCTGAGCTGTAAAAACCTGAACTCAATTCAGGGGTACAAATTGCAATCTAATCTTTTCAGGGAACCAGGGATTTTTTTCTCTCTCTCTA GACAATATGTTTCCTCATTAGTCTGCTAATGAAACACTTCTTCAAGTTCCCCAAGTGGGAACAGGTCCATCATTCCCTTAGTCAAAACTT TGGACACAGGCTACGTCATACAAGTAAGCAAACAGTAAGAGAAAAACAAAATGTGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCA CTTTGGGAGGCCGAGGCAGGCGGATCACGAGGCCAGGAGATCAAGACCATCCTGGCTAACATGGCGAAACCCTGTCTCTACCAAAAATAC AAAAATTAGCCAGGCGTGGTGGCGGGCACCTGTAATCTCAGCTACTCGAGAGGCTGAGGCAGGAGAATCTCTTGAACCTGGGAGGTGGAG ATTGCAGTGAGCCGAGGTCGTGCCATCGCACTCCAGCCTGGACATCAAAGTGAGACTCAGGCCAAAAAAAAAAAAAAAAAAAACCTTGAC GTGTCAATGTTTGTGTCTGGCCTAGGAGAATGAGGATGACAGCTTCACTTGCCTTTTGAAGAAGAAACATTACAAAACCTTAATCTGAAG TATAAAGTCAAAAGATACGGCTCTTTCTCACACTTGCAAGACTTACAAATACAGCCTCAAACATTATGACACACCAACAATATCTAGAAA GTAAGAACTGGTGTAGCAATGATGCTTCATATTCTAGCTGTAGCCACAGAGTTGAGGGTAGTTTTTGTAGGTCTAAAATAATAATCTATA AAGATGTCCAAAGTTAAATTTTCAACAATACAAATCTAGAGAAGTGACAGCCTACATTACTTCATTATTACTCTTCTTTTAGTCTTTAGT CTTTAATATTTTAAAGTTTACTCTATAAATCAGCATTTTGTAATCCTTTATAAACTCATCCAGATTTAAATGCTACTTTTTCATGAAGAA AGGATAACTTTATAGACAGTCAGTGCAACACACACATTTTATCTCATCACCGTCTTACTGCCTCCCCATCCACTGTCTCATAAAGCCCTC AGCTGAACTAAGATAAATAATACAATGGAAATTATTTTCAGTTCCCCTTGCACTGTCAAAGTAAAACAAGAAAACTGAAAAGCTGCACCC CCAGCAAGAAAGGGAAGTATGCTGTTGTATGCATCATTACTCAACAATTACCCTCTAACTAAACATCCTGTTTAAGAGTTTAATTCAAAC AACAGCCAGACTGTTAAGAAAAAAAACAAAAAGAATAACTTTTATCTGGCTTACAATTATTAAAGCATTTATTTTCAGGTACCAAAAGCC ATATCCCATTCCACTTTTTAAGTTTCTTTTGATCACTGACAGGCATTAACAGATGTAGCAACGTGGTCTCCTATAGAGAAAATTACACTT ATCTAAAAATCTGATTCCATTAATTGATCAAGTATAAAAATCTACGAAAACAATATGTTCTGCACATCACATCTGTACTTTTTTTTTTTT AAATATATTTTTTGAGACGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTCCGCCTCCCGG GCTCAAGGGATTCTCCTGCCTCAGCCTCAGCTGGTATTATAGGCACTTGCTACCATGCTTGGCTAATTTTTGTATTTCTAGCGGAGACGA GGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTG TGAGCCACTGTGCCCGGCCACATCTGTACTTTTAAGGGTACAGCTTTACAGTACATAGGAATTTGAGAACCACTTCACAGGAAGAGGGAA ACAGCCCAATATTTATTTATGTATACACATAATCCCAAGTGTGTGCTGGGGCCACCAGGCCCTTCCTGGGGGAACAAGGACTGTCGTGCA TGTGAGTGACGACATTAATAGCATTTACATACTGTACAGATGCAACCTTTGATGATACATATATTTGATAAAAATGAGAAAACAGATTTG TTGTAGAGTACCTGTCCACTTTTATAGCATGAGAACAGTACAATCAACTATTTATTTTGCAGTTACTCATTTCAGTGATTGAGAATTTCT GTGCTGTGCAGAGAGACGGCCTGTAATTGGTCTCATCATCCACTTGATTCTAACATGATCTCTGCCCAAAGTTCCATTTCTTGGGCTTTG ATATTTATAATGGCGCCTGCTCTTCATCTTGTCTTACGCTTTCCGAGCAAGTTCAAACCAGAAAGAAAAGGTGAGGCTAGAAGCCCAAAG TGAGTGAGTGTGAGGACCACAAGGAAGCCCACCACTCCACAGTAGATGATCAAAACCACATCCTCACGTGGGAGGTAGCACTTGGAGAGG GTGTAGTCTGTGGGCGTGATGCTACCCTGGAAAGGAGAAGGGAAAGTTATGCTGAGAGCACCAGGCACACGTTGAACACCGCAGTCTTAG AAACAGCAGAGGGAAGACTGCCTTCTCAGGTCCCCCTCAGGTGAGGCAGGGAACGGGCCCTCCTCACCTGAGACCAAGGGGGCCCAGCCT TCTCCCTGCACAGCTCACCCCCGACCAGCCCAGGCTCCAGCAGGAGAGACAAGTAAGGCCCAAGTGTGCCTGAGTGGAAAATGTCTGGGA CACTGACCTGTCAAAACTGGCCCCTGGCTCACTGGGTTCCCATCAAATATAGTGGGGGATCCATAACAGAGATTCAGAGAGGCACCGTGG AGTTCCAGGGTCATCGGTCAGCGAGGAACAAGGAGGGAAAGGTGTCTTCCTGCCCCTTGATGCTCAACTAAGCATCTGTTCCCTAGAAAT ACATGTGTCCAGGTCGTCTCCATGGGCTTTTCTTTGCAGATACTTTTATGTGGAACAACAGTGGCAAATGTTTTCATTTACTTTGAATTT GAAAATGTTAGGGTTTCCTCCACCTTTTTATGAAGTAAAAGAACCTGTCGTACCAGCATCATGAGCTGGATGCAGGAGCCCATGGCTGAA AGGAGTTAAAACGCCCAGTGGTCATTAAGTGAAACATCTTTTATCAACCTGCAAAAGCTGCAGCGTTCTCTGCCAGGTCAAATGGGCATG TTTAGAAAATAAGAGAAGATGGCTGAGTATAGCTAATGAATAAATGGTTGTTTCTTTAGAAAATTAAACACACACAGAGTGTAAGAGGAG AGGATACGGCCCTCCCTGAAGGATAAAGTCCACCTGGACGGTGCCCTGCCCTCGCTTCTCACATTAACTGCCCAGGAATGTCATGCTGAT TGGTTCCCGGAAGGGTGTTTGGCAAGGGGCAGTGTATGGAGCTACGTGTAGAAGGAGAGAAATTTGTGTGTGGCTTTTGTAAATTTTGAC CGATTGCAGCAATTAAATAGTTGATTACTGTGTTGATTTAAATACTTATGAAAGCTTTCAGACAAAAATAAACTTTCACGTTACCATGAT >29067_29067_6_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000334049_length(amino acids)=238AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- >29067_29067_7_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000423027_length(transcript)=1912nt_BP=469nt GTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCCGCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGA GGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTCCCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGA GGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGATAGAAGGACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCT TAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGCCAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTAC AGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAGAAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGC TGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTTGACTACACACCCACAGACCAGGACCTCCTCAGATGCA GAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAACTTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGA GGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCAGCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATA ACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAACAACAGGTGGTTACGGACCATTTCTATCATCTTGTTCT TGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATTGAAGACTATTTCCCAGAATATGCAAATTATACTGTTC CTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAGTTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGG CCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGACACAGAGAACATCCGCAGGGTGTTCAACGACTGCCGCG ACATCATCCAGCGGATGCACCTCAAGCAGTATGAGCTCTTGTGAGGATGCTGCCGCCACCCTGCGACGGAGCGGCGCCCCGGACTGCCTG ACTGCCAGCCCCATGCCATGGTAGGAGGCAGAGTCTCTAGTTCCATCTCGCTGCCGTCTGTCCCGTTCTGTGTCGACCACCAAGCCTCTG GCTACCTCTGTCCCCTCAGGTTTGGTTGTGTAGCTTCTGTTGTCATTGAATACGGCCTCCCGCAGCATCCCACCCCCAAACCACCGACTC TCATTGCCGACACTGCAGCAGAATCTCTCCGGGTGGGAGCCCCATTATTCATTCTCCCTTTATTGATTCATCGAGGAGAACTTGGTAGAT GGGGAGAAAACACAGTTGGTTTTTTTTTCCACGTTATCAACCGTGACTGCAAGAGCGTTCGTGCAGTGCCCTGAGCCACGGCCGTCTCTG ATTCTCCCTTTATGAAGCTGCAGGCTGACGAGAGATGGTCCCTTCCCATTGGCCTTAGCCCAAGACTTGGAGTCGACCCCAAGCGACAGA GTGACCAGAAACCCTTTTACAGTCACATTCAGAGTCGCTGCTGGCCTCAGGCATTTGAATTAGAGCTACTTTGAGCCTCTTAGGCAGAAA ACCTACCACATTCACTACTGCAAAATGTGTCCTGTCTAAAAATGATTCTCTAAACTTTCCCTATACTTAGGCATAGTCTTCTTTCTTAGA TTCTCTTTGTTGTTGTCCCTATTGCTGGTTTATTACACTGTACAGACCACAAAATGTAATATTCTTTTGTATAACTACTAAAGAAAAATC >29067_29067_7_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000423027_length(amino acids)=238AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- >29067_29067_8_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000535121_length(transcript)=1124nt_BP=469nt GTCGTTACCCTGTACATCCGGGTCACTTGCCCTCCCCGCTCGGAGCTGCCGCCTGGCTTGTCGCGGCTCTGCCACAGGGGCAGGTGTTGA GGGGCTCCCGGTCCGGCTGCCGCCGCTCCCCCGCTCCGGACCCGGGGCTCCCCCTAGCGCCGCTGAGGAGCCGCCTCTGCGGCTCCAGGA GGGCGCAGGAGCGGGACTGAGAGCGCCTGGAGGCTCGAGCGGAGGATAGAAGGACAAGGACAGAATCACCAGCACTGGCTGAAGGTACCT TAACATGGGGAATCTTCTTAAAGTTTTGACATGCACAGACCTTGAGCAGGGGCCAAATTTTTTCCTTGATTTTGAAAATGCCCAGCCTAC AGAGTCTGAGAAGGAAATTTATAATCAGGTGAATGTAGTATTAAAAGATGCAGAAGGCATCTTGGAGGACTTGCAGTCATACAGAGGAGC TGGCCACGAAATACGAGAGCTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTTGACTACACACCCACAGACCAGGACCTCCTCAGATGCA GAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAAGTAAACTTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGA GGAGAAAATGGATCCAGTGCTTTAACGATGTCACAGCTATCATTTACGTCGCAGCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATA ACAACACCAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAACAACAGGTGGTTACGGACCATTTCTATCATCTTGTTCT TGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATTGAAGACTATTTCCCAGAATATGCAAATTATACTGTTC CTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAAAGTTACAAGAGCCAAGTTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGG CCACCGGTGACGGCAAACATTACTGCTACCCGCACTTCACCTGCGCCGTGGACACAGAGAACATCCGCAGGGTGTTCAACGACTGCCGCG >29067_29067_8_FAM49B-GNAL_FAM49B_chr8_130883621_ENST00000519824_GNAL_chr18_11862394_ENST00000535121_length(amino acids)=239AA_BP=20 MQKASWRTCSHTEELATKYESFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIY VAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTR -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for FAM49B-GNAL |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for FAM49B-GNAL |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for FAM49B-GNAL |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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