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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FARS2-LYRM4 (FusionGDB2 ID:29404)

Fusion Gene Summary for FARS2-LYRM4

check button Fusion gene summary
Fusion gene informationFusion gene name: FARS2-LYRM4
Fusion gene ID: 29404
HgeneTgene
Gene symbol

FARS2

LYRM4

Gene ID

10667

57128

Gene namephenylalanyl-tRNA synthetase 2, mitochondrialLYR motif containing 4
SynonymsCOXPD14|FARS1|HSPC320|PheRS|SPG77|mtPheRSC6orf149|CGI-203|COXPD19|ISD11
Cytomap

6p25.1

6p25.1

Type of geneprotein-codingprotein-coding
Descriptionphenylalanine--tRNA ligase, mitochondrialdJ236A3.1 (phenylalanine-tRNA synthetase)dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase))mitochondrial PHERSphenylalanine tRNA ligase 2, mitochondrialphenylalanine translasephenylalanine-tRNA synthetase 1 (LYR motif-containing protein 4homolog of yeast Isd11mitochondrial matrix Nfs1 interacting protein
Modification date2020031320200313
UniProtAcc

O95363

Q9HD34

Ensembl transtripts involved in fusion geneENST00000274680, ENST00000324331, 
ENST00000464010, ENST00000468929, 
ENST00000480566, ENST00000500576, 
ENST00000606472, ENST00000330636, 
Fusion gene scores* DoF score19 X 11 X 13=271710 X 6 X 6=360
# samples 2111
** MAII scorelog2(21/2717*10)=-3.69355333255585
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/360*10)=-1.71049338280502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FARS2 [Title/Abstract] AND LYRM4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFARS2(5613553)-LYRM4(5216971), # samples:2
LYRM4(5260881)-FARS2(5771524), # samples:2
Anticipated loss of major functional domain due to fusion event.LYRM4-FARS2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
LYRM4-FARS2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFARS2

GO:0006432

phenylalanyl-tRNA aminoacylation

10329163

HgeneFARS2

GO:0008033

tRNA processing

10329163


check buttonFusion gene breakpoints across FARS2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LYRM4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D3-A2J9-06AFARS2chr6

5613553

-LYRM4chr6

5216971

-
ChimerDB4SKCMTCGA-D3-A2J9-06AFARS2chr6

5613553

+LYRM4chr6

5216971

-
ChimerDB4STADTCGA-HU-A4GN-01AFARS2chr6

5261893

+LYRM4chr6

5216971

-


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Fusion Gene ORF analysis for FARS2-LYRM4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000274680ENST00000464010FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000274680ENST00000468929FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000274680ENST00000480566FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000274680ENST00000500576FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000274680ENST00000606472FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000324331ENST00000464010FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000324331ENST00000468929FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000324331ENST00000480566FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000324331ENST00000500576FARS2chr6

5613553

+LYRM4chr6

5216971

-
5CDS-intronENST00000324331ENST00000606472FARS2chr6

5613553

+LYRM4chr6

5216971

-
5UTR-3CDSENST00000274680ENST00000330636FARS2chr6

5261893

+LYRM4chr6

5216971

-
5UTR-intronENST00000274680ENST00000464010FARS2chr6

5261893

+LYRM4chr6

5216971

-
5UTR-intronENST00000274680ENST00000468929FARS2chr6

5261893

+LYRM4chr6

5216971

-
5UTR-intronENST00000274680ENST00000480566FARS2chr6

5261893

+LYRM4chr6

5216971

-
5UTR-intronENST00000274680ENST00000500576FARS2chr6

5261893

+LYRM4chr6

5216971

-
5UTR-intronENST00000274680ENST00000606472FARS2chr6

5261893

+LYRM4chr6

5216971

-
In-frameENST00000274680ENST00000330636FARS2chr6

5613553

+LYRM4chr6

5216971

-
In-frameENST00000324331ENST00000330636FARS2chr6

5613553

+LYRM4chr6

5216971

-
intron-3CDSENST00000324331ENST00000330636FARS2chr6

5261893

+LYRM4chr6

5216971

-
intron-intronENST00000324331ENST00000464010FARS2chr6

5261893

+LYRM4chr6

5216971

-
intron-intronENST00000324331ENST00000468929FARS2chr6

5261893

+LYRM4chr6

5216971

-
intron-intronENST00000324331ENST00000480566FARS2chr6

5261893

+LYRM4chr6

5216971

-
intron-intronENST00000324331ENST00000500576FARS2chr6

5261893

+LYRM4chr6

5216971

-
intron-intronENST00000324331ENST00000606472FARS2chr6

5261893

+LYRM4chr6

5216971

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000324331FARS2chr65613553+ENST00000330636LYRM4chr65216971-857315533361742468
ENST00000274680FARS2chr65613553+ENST00000330636LYRM4chr65216971-839313731561562468

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000324331ENST00000330636FARS2chr65613553+LYRM4chr65216971-0.0030101480.99698985
ENST00000274680ENST00000330636FARS2chr65613553+LYRM4chr65216971-0.0026639860.997336

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Fusion Genomic Features for FARS2-LYRM4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FARS2-LYRM4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:5613553/chr6:5216971)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FARS2

O95363

LYRM4

Q9HD34

FUNCTION: Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. {ECO:0000269|PubMed:19549855, ECO:0000269|PubMed:22833457}.FUNCTION: Required for nuclear and mitochondrial iron-sulfur protein biosynthesis. {ECO:0000269|PubMed:17331979, ECO:0000269|PubMed:19454487}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFARS2chr6:5613553chr6:5216971ENST00000274680+67157_160405452.0RegionNote=Substrate binding
HgeneFARS2chr6:5613553chr6:5216971ENST00000274680+67186_188405452.0RegionNote=Substrate binding
HgeneFARS2chr6:5613553chr6:5216971ENST00000274680+67193_195405452.0RegionNote=Substrate binding
HgeneFARS2chr6:5613553chr6:5216971ENST00000324331+67157_160405452.0RegionNote=Substrate binding
HgeneFARS2chr6:5613553chr6:5216971ENST00000324331+67186_188405452.0RegionNote=Substrate binding
HgeneFARS2chr6:5613553chr6:5216971ENST00000324331+67193_195405452.0RegionNote=Substrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFARS2chr6:5613553chr6:5216971ENST00000274680+67358_450405452.0DomainFDX-ACB
HgeneFARS2chr6:5613553chr6:5216971ENST00000324331+67358_450405452.0DomainFDX-ACB


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Fusion Gene Sequence for FARS2-LYRM4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>29404_29404_1_FARS2-LYRM4_FARS2_chr6_5613553_ENST00000274680_LYRM4_chr6_5216971_ENST00000330636_length(transcript)=8393nt_BP=1373nt
GTCAAAATGGCAGCGCCCAGCGTGCGCGGGTATCTCTGAAGTTGGGGTTTAAGATTCTTGCCCGTGAGAGCGAACGAGCCTGCCGTACTT
CTGATTTTGAAACACCTGGGTCTGGGCTTCCCGGGCGAGCGGTGGAACCTGTGAGAAGTTTCTACAATGGTGGGCTCAGCTCTCAGGAGA
GGTGCCCATGCATATGTCTACCTGGTGAGTAAGGCCAGTCACATCTCCAGAGGCCATCAGCACCAGGCCTGGGGATCGAGGCCTCCTGCA
GCAGAGTGTGCCACCCAAAGAGCTCCAGGCAGTGTGGTGGAGCTGCTGGGCAAATCCTACCCTCAGGACGACCACAGCAACCTCACCCGG
AAGGTCCTCACCAGAGTTGGCAGGAACCTGCACAACCAGCAGCATCACCCTCTGTGGCTGATCAAGGAGAGGGTGAAGGAGCACTTCTAC
AAGCAGTATGTGGGCCGCTTTGGGACCCCGTTGTTCTCGGTCTACGACAACCTTTCTCCAGTGGTCACGACCTGGCAGAACTTTGACAGC
CTGCTCATCCCAGCTGATCACCCCAGCAGGAAGAAGGGGGACAACTATTACCTGAATCGGACTCACATGCTGAGAGCGCACACGTCTGCA
CACCAGTGGGACTTGCTGCACGCGGGACTGGATGCCTTCCTGGTGGTGGGTGATGTCTACAGGCGTGACCAGATCGACTCCCAGCACTAC
CCTATTTTCCACCAGCTGGAGGCCGTGCGGCTCTTCTCCAAGCATGAGTTATTTGCTGGTATAAAGGATGGAGAAAGCCTGCAGCTCTTT
GAACAAAGTTCTCGCTCTGCGCATAAACAAGAGACACACACCATGGAGGCCGTGAAGCTTGTAGAGTTTGATCTTAAGCAAACGCTTACC
AGGCTCATGGCACATCTTTTTGGAGATGAGCTGGAGATAAGATGGGTAGACTGCTACTTCCCTTTTACACATCCTTCCTTTGAGATGGAG
ATCAACTTTCATGGAGAATGGCTGGAAGTTCTTGGCTGCGGGGTGATGGAACAACAACTGGTCAATTCAGCTGGTGCTCAAGACCGAATC
GGCTGGGCTTTTGGCCTAGGATTAGAAAGGCTAGCCATGATCCTCTACGACATCCCTGATATCCGTCTCTTCTGGTGTGAGGACGAGCGC
TTCCTGAAGCAGTTCTGTGTATCCAACATTAATCAGAAGGTGAAGTTTCAGCCTCTTAGCAAATATCCGGCTGTGATCAATGATATTTCA
TTCTGGTTGCCCTCTGAGAATTACGCAGAAAATGATTTCTATGACTTAGTCCGAACAATTGGAGGAGACCTGGTGGAAAAGGTTGATCTC
ATAGACAAGTTTGTACATCCAAAAACATATGCTGTCAGGAGGATAAGAGATGCCTTCAGAGAAAATAAAAATGTAAAGGATCCTGTAGAA
ATTCAAACCCTAGTGAATAAAGCCAAGAGAGACCTTGGAGTAATTCGTCGACAGGTCCACATTGGCCAACTGTATTCAACTGACAAGCTG
ATCATTGAGAATCGAGACATGCCCAGGACCTAGCAAGCCGGGGACCAGCCACCAGTGGCGGCCAGGGACCACCTTCAGCATCCACTCTCT
GTTTGAGATGGGGGCTCCCAAAACCAGCTTACAATAGCCTTTTGCGCTGCCTGTCCTGTGGGAGCTGATAAACCAAGTCACATTTGCATT
CTGTTGCAGGCTTAGTGAAAAAGGACTGCTGTCTTTCCTTGGTTCAAGTGTTAGAATGGAGAGCTGGAGTTCGTTCAGAATAGTGCTGTG
TGTTACCACGTCTCCCCTGCACCCCATTCCTACCTTGTAGCTCATGACCATTGTGTATAGCATTTCTACACTTTGTTTCTTGGTCCTTGG
CAATAAAAAGAATGATCTCCCTGAGCCTTTGACCCCAGATAAACCCCTCCCAATTAATGCATTTTCATTTCCTACTGATACAAGGCCTGG
AGAGGGCTGTTGGGGGCCCTCAGGGAGGGTTCAACTCTGAGACGAGAACTGCCTTGGTGAAGGCAAGTTCAAGCACCACTTGAGACTGGG
GGCAGCATGGAGTAGGGCAGGGCTACGGGGATACACGGTGCACCCTGCAACTTATACCTGAGCCCAGTACAACAAAGGTGACGGGTGTGT
AGGTACACACCCAGAGATGGAGCACTGCAGATCAGCAACCTCAGCCCCACCTGGGAATTTGCTGGAAATGCAGGCTCAAGCCCCTCCCCA
CACCTGGTGAATGAGAGAGCCCCAGCCTGACCCAAGCCCAGGGCGACTCCCATACCCTGAAGCCTGGGGCATGCTGGGCAGCACCGGTGC
CCAAATCTGGCTGGTGGACAGAAGCACCTGGAGAGTTGGAGAGCTTTTTAAAAAGACATCTCTCAGCACTTCCCTCTCTGCAGATTCTGA
CTCAGTAAGTGAGGGGTGAGGCACAGTCATTTTTCTCTATTCTGAAGCTCTCCCACTGTTTTCAATGTTTAACCAACTGGGGACCCCTGC
TCTTTAAGTATATTACAGGTAATAAAGATATTGTTTGTATGCTTTTATTCTTGGAAACAGATTCATTCCAAACATAGAAAGAACATATTA
AATAACTTGCTTGTCATCTGGGGAGTTTACGAGGGACCAGACCTGGCAGAGCGGTTTCTTGTTTCCCTTTGCATACAGTGCTCAGTGGAT
TTGGTATCTGTGGGTTAAGGTTTGGAACAGGCTCCTATAAATAGCACCGGTCCTGGAATAGCTGCAGCACTGTCACCCCCTCATTTTAAC
TCCGACGGTCATGGGAGTGAGTACGCACTGTCTGAGCCCGTGTTCTTCTCACCCTCATATGAGAACTCATGTCTTCCAGTCGCTTTTAGA
GAGCATAGATTTGCTGCAATGATGCGTTCAAATAGATGTAACGTGTAGCCATTCTATTTGGCAGTACAACTTTTGATTTCAGGATAAAGT
CTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGCGGTGCGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTT
CAAGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGGGCCTGCCACCACGCCCAGCTAATTTTTTGTATTTTTAATAGAG
ACGGGGTTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTCGGCCCCCCAAAGTGCTGGTATTACAGGCATGAACCACCACCCCCTGCC
AATTTCAGGATAAAGTCCTGAGCATCTGTGAAAATAATGAAGCTCTTAGCAAGTCCCAGATCTCTTACCCTCTAACCAGTTCCTGCCTGG
GAGCTGCAGTGTTAGAGCATATGCAAAGCCCTAATTGGGGGAGAGCTGTTCGGTGGACAGTGAACGGAGGTGATGTGGCAAGTATAATCA
CTCCCTTCAGCTGACTGTCACGGGGCAGAGCCGCCCAGCCCAGCCCTGTGTGTGGCTCTGGCTCAGGTTTTCCACCTTGCATCAGTGCAG
TGGAGTTCGTGGTCACTCAGCAGTGAATGCATCCAACCACGCTACTAACGCACGGCACTGCTGATTTATACTTAATTTAAGCAACTGCTA
CTTGGAACCGAAGTCCAGATTTGAACCTCCGTGCTGAAGGCATCAAATTGCCGGCAAGATAACAGCTCCAGAGGAGACTTCTCCCACTCC
CCCAGGTTTTACGCAATGAGGCAGTCCACCCAAACTTAACGTGGGCTGCAGGCTGTAACAGCAGGTTGCTTTTGTGTTCATTAAACTGCA
TGAATGGGTTTGAACATGCCCAAAGCCTTGCTAATGCAGACTTAATTTTGTAAAATTAACTATGCCTTTGGAATCTGCAGAAAGATACAA
ATCCGAATTCTGTGGCAGGAAACGCCACAAACAGGCCTTGGTCCTCCACCTTTCAGGTGTATATCTGGCAGGCAGAGCCTGGCACTGGGT
ACTCCCCAACTGAGATGACCCAATATTGATGCTAGAGCTTCGAATAAAGTGGCATTCCCATGGGGGTGACCCCTGGTGTTTCTCTAGGGA
AGTATTCCACCTCCTTGACTATGCACCAACTGAGGGGAATGTGGGCAACTCCAACATCCATCATGGCCAGCCTCACAGAACTCTCTAGAA
CTTGTGCCTGCTTTGAAGATAGGATCCGGGCTGGGGTCTGGAGATCACTTTGCAGCACTAATATTGAGCAAATGAGAACTACTATCATTA
GTTAACTTCCCAGGCAGAACTCATTGGCCGAGCAAGGCTATATCCTAGACTTTCAGAGACAGCTCTGGGCTGGGCTGGCTGTCATGACAT
AATAGCTGGGAGATCTTGCACGGCCAAGTACAGGGCTGTGTTGTTCTGATGGCTGTTGGAATCTGGATTTTGGAACTGAAAGAATTGGCT
AGATTGCTTTAGGTATACTCCGTCCTGCTGCTAACTAAGTAGCAGTGACCTTTAACTCCCTTCATCCACAGCCTCTCCCGTTAATCTCAA
GCCCCACCATACAACCCACCATCATCCAGGAGCAAAAGGGACAGGCAGAGGGTGAAGCCTACAAAGATGACAAACATCAGAGCTCACCTA
GTCCAACCCTCAAATCTTCAGGTGTTAAAACAAAGAGCCTGAACATCTGCAGATCACGTACAGAGTCAGGGCCTTTCCCCTAAACCCCTT
TCACTCATTCATTTATTCACTCAGTATTGACTAAGGCCACCTAGTGCCAGGTGCCAGGTGCCAGGGAGCAACCAGTGAACAAGACAGACG
TACCTTCATAAAGCCTGTGTCTAGCAGGGAAATCTGAGAAGAAAATGACAAGTCTTATGAATGTTACAAAGAGGGAAATATGAGTGCTGC
CAGAGCCGATGGGACGGGCCAGGGAAGGGCTCCCCAGGGGATATTTACACGTGCAAATTAATGATGAGGATTGGCTGTGTGAAGGTGGGG
AGAGGAGCTCTCTAGGCAGGAGGAACAGCACATGCAAAGCCCTTAATTGGGGGAGAGGGTAGTTCCATGCAAAGAACTAAAGGGAGTCTG
GGATGGTGGCAGCCAAGGAAGAGGGCTCTTTCCACATCGTGGACGGCCTTGGAGCCTCAGCCTAAGGATGGTGAGCAACTCGGGAGTTTT
TAGGCAAGATGAGGTTTTTGTTTTGTTTTGTTTTGTTTTTTTGAGACAGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATAAT
CTCAGCTCACTACAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCACGCCACCA
TGCCCAGCTAAGTTTTATATTTTTTAGTAGACACAGGATTTCGCCATGTTGGCCAGGCTGCTCTTGAACTCCTGACCCCAGATGATCCGC
CTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCCCCCGACCGAAGTTTGTATTTTTTAAAAGGTCACATTGTCTGC
TTTTGAGGGGATACACTGGGAGAGATGCAGGGAGACCAGCTTTTCGGAGGAGTGGGGGATTGGGTGTGGCATTCCAGGCAAGCGATGGTG
ACTTCACCAAGAGGCAACAGCTGAACAGAAGCAGAGTCAGCATCACCCTGAGAACTGGCTGGGGTGGGCCGCCATTGAAGGAGGACAGGA
AACCTGGAGCAGAGCTGCCCCAGCTGAGCACAGCCCGAGCTCCCCAGCCCACCTGCCGATGCGCGAGAAAGTCCACAGAGTCCCCTAGCC
TGGTCTAGCTTAGGTCAGTCATATTCAGCCACCCCTCAGACATGTGCTAAATAATTAACTGTTACATTAGTCACTGAGTTTGGAGGTAGA
TTATTATGAAGTAACAGCAAACTAATACAGAGAGCATCTCTGTATTAATGTATTAATGTATTACTTTCTCAGGGCCACATAGCAAACCAA
AGAGTAGGCAGACAAACGGCCAAAACTGCAGGTCTCCTGTATGGGGACATTTCCACAAATATCTTCAGAATACTGGTCACTCCCTTTAGA
GAACAAGTCCTGGAGAAACAGTCGAAACAGTCATCACGTGTCCTACAGATGGAAGGGCTGGCCAACCAGAAAGAAAAGAAAAAGTCGAGT
CAGCAGAACTTGGTGATTGATTGGATGAGGAGACCAGGCCTGAGGGCTGCAGGGAGTCTAGGAGGAGTCTCAGGAGCAGGGCCTGAGGAA
CTAAGAAGGGGCTCTGGCTGAGACCAGACAGGAGCAGCCACTGTCTGGAATTTTGTCCCCACTGCTGACTTCGAACAACCTCAACTTCAA
ACAGAAAGCCCAGACTCGATGAATTTATCTTTTCTTCAAAGTAGAGAAAGGGTAGCTCTTTTCTTCCCAGGAAATTGTTTATCCATTTAA
TAATTTTTAAAAATCACTGGAGTTGGGTGTGGTGGCTCATACCTGGTAATCTCAGCACTTTGAGAGGCCGAAGTGGGCAGATCACTTGAG
CTCAGGAGTTCGAGACCAGCCTGGGCAACATAGTGAAACCCTGTCTATACAGAAAATACAAAAATTAGCTGGGTGTGGTGGCATGCAACT
GTTGTCCTAGCTACTCTGGAGCCTGAGGTGGGAGGATCACTTGAGCCTGGAAGGCGGAGGTTGCAGTGAGCCATGATCGCACCACTGCAC
TCCAGCCTGGATGACAGAGTGATACCCTGTCTAAAAAAAAAAAAATAACTGGGATAAAACAACTCGAAAGACCCTTATAAAGATTTTACC
CGTAACTCTGTAGAGCAAATAACTTCCTGCTTTAGGCAAAGCTCTTTGTGTGTAAGTTCGATTGGAAGAGGAGGGCTGGTGGGGGGAGAT
TCTCTACTTTGGTCATGAGATTAACATTAAAAGTTTGAGGAAGGTTGCTCTATATATTGGCTGCCTGTTTCTAAGACTGAAAATAAAAGC
ACAGTAAAATATCAACAAGTATACAGAAAATATACATTTGTAGAAAATTAGCTTTTTTTTTTTTTTTTGCTAAGTACTTCATATAAACTA
GTATTTGCTTTCTAGATTAAAGAATATCTCCTCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAAGCCGAGGTGGATGGA
CCACGATGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTCCTAAAGATACAAAAAAAATTAGCCAGGCGTGGCA
GTGGGCGCCTGTAATCCCAGCTACTCAGGAGACTGAGGCAGAGAATTGCTTGAAGCCAGAGGCAGAGGTTGCAATGAGCCGGGATCACGC
CACTGAACTCCAGCCTGGGTGACAGAGTGAGACTCTTGTCTCAAAAAAAAAAAAAAAAAAAAAAATATCTCAGATATTGAAGCGAACCTA
TAAATAACAGCAGAAGCTGAAGAAAAGATAACGGATCAAAAAGCAGAAGGAGAAAGCTTCCCTGTCCCCAAGGACCTGCCCACAGTCGTG
GATGAGAAGTCCCTTGATAAGTAGGGTCTGAACCCACGTGATCAAATGTTAGCTCTGTGAACCTGTGCCAGTGGCTGTGTGTCAGTAGCC
CAGGGTGATTCAGAAGCTCCATGAAGCAGCCATCTTTCCTGGATCTCTGGAATGTACACATTTGCTGAGATCACAAAGATGAAGCTGGCA
GAACCCGAGTGGATATTCATTATTACGAACAGAAGAACAGCCAACAGGAGCCGTGCCATGTGCAACCCCGAGTTGACAGATGCCTCCCCG
CTTCTTCTGTGTTTGCCAGTTGTTACAAAATGATCTAGAGAAAAACTGGAACTTGATGGAGAAAGCAATGGCTTACGATTCAGCAGGCTT
TCTTGGAGAGTTTACCTAAAGTCTATGTGGACGGTGGCTCAGCTCACCTCTGAGAACAATACGATCTTCACTTTTCAATCTTTCTGCAGC
TCTAATTAGTGCCACAGGGAACCATGGATGAAAATGGCTTCTCGTGTTGATATCCATTTGGGGAATAGGATGGATGCAGCTGCTTTTGCT
CAAGGGCAGAGTTTTGACTTCAAAGACCCTGAAGAGAACCCAGAAGGAAAACTCTCAGAGGTCAATGGACTATATTCTTTACCTGGGGGA
TCGTTGACACCACAGCAGTAAAAGCGAAGTCAGTGTCGTGCTGTCTTGAAATTAGATGACAAGAATGACTGACACCAATAGAGCTGGAAC
TGCACTTGGAGCCTGAGTAGCCGGTCTCAGGCTAACCACACCTGTGCTGACCACAGCGTGGCCCGTGTTGTTCATGAGGCATTCTGGCTG
TACCTCCACAGGGATGCAAGACTTCCAGTGAGAGGCTGCTTCTGCAAGAAAATACCTGCCTAGAAATGGTCCGCTTTCTCTTCCTAATAA

>29404_29404_1_FARS2-LYRM4_FARS2_chr6_5613553_ENST00000274680_LYRM4_chr6_5216971_ENST00000330636_length(amino acids)=468AA_BP=406
MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIK
ERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRR
DQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPF
THPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKY
PAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIG

--------------------------------------------------------------
>29404_29404_2_FARS2-LYRM4_FARS2_chr6_5613553_ENST00000324331_LYRM4_chr6_5216971_ENST00000330636_length(transcript)=8573nt_BP=1553nt
ACGCGGCGGGAGGGCGGGGAAATAAGAGGACTGGCCGCCCGTGCATCCAGCCAAGCTCCTGGCGGACGGATATCGGAGGCCCAGGCATTC
GAGGGACGTGCAGTTGCATCACGGAGAGCCTTTGGGAACCGTCTGGGGTCTTGGCGGAGACATTTGTGTTTCGGGGGCAGCGCCCCTTCC
TACATCCAGGAGGCCGCGTTGCCCGGGTTACCGAAGGCCGCCGCACCGACGCCCCGCCCCTGACCGCCGATGCCCCTCCCACGCCGGCTG
CGGTCGCCCTCGGCGCTGCCTGAGAGAGTTTGCGGGATTTCAAGGAACCTGTGAGAAGTTTCTACAATGGTGGGCTCAGCTCTCAGGAGA
GGTGCCCATGCATATGTCTACCTGGTGAGTAAGGCCAGTCACATCTCCAGAGGCCATCAGCACCAGGCCTGGGGATCGAGGCCTCCTGCA
GCAGAGTGTGCCACCCAAAGAGCTCCAGGCAGTGTGGTGGAGCTGCTGGGCAAATCCTACCCTCAGGACGACCACAGCAACCTCACCCGG
AAGGTCCTCACCAGAGTTGGCAGGAACCTGCACAACCAGCAGCATCACCCTCTGTGGCTGATCAAGGAGAGGGTGAAGGAGCACTTCTAC
AAGCAGTATGTGGGCCGCTTTGGGACCCCGTTGTTCTCGGTCTACGACAACCTTTCTCCAGTGGTCACGACCTGGCAGAACTTTGACAGC
CTGCTCATCCCAGCTGATCACCCCAGCAGGAAGAAGGGGGACAACTATTACCTGAATCGGACTCACATGCTGAGAGCGCACACGTCTGCA
CACCAGTGGGACTTGCTGCACGCGGGACTGGATGCCTTCCTGGTGGTGGGTGATGTCTACAGGCGTGACCAGATCGACTCCCAGCACTAC
CCTATTTTCCACCAGCTGGAGGCCGTGCGGCTCTTCTCCAAGCATGAGTTATTTGCTGGTATAAAGGATGGAGAAAGCCTGCAGCTCTTT
GAACAAAGTTCTCGCTCTGCGCATAAACAAGAGACACACACCATGGAGGCCGTGAAGCTTGTAGAGTTTGATCTTAAGCAAACGCTTACC
AGGCTCATGGCACATCTTTTTGGAGATGAGCTGGAGATAAGATGGGTAGACTGCTACTTCCCTTTTACACATCCTTCCTTTGAGATGGAG
ATCAACTTTCATGGAGAATGGCTGGAAGTTCTTGGCTGCGGGGTGATGGAACAACAACTGGTCAATTCAGCTGGTGCTCAAGACCGAATC
GGCTGGGCTTTTGGCCTAGGATTAGAAAGGCTAGCCATGATCCTCTACGACATCCCTGATATCCGTCTCTTCTGGTGTGAGGACGAGCGC
TTCCTGAAGCAGTTCTGTGTATCCAACATTAATCAGAAGGTGAAGTTTCAGCCTCTTAGCAAATATCCGGCTGTGATCAATGATATTTCA
TTCTGGTTGCCCTCTGAGAATTACGCAGAAAATGATTTCTATGACTTAGTCCGAACAATTGGAGGAGACCTGGTGGAAAAGGTTGATCTC
ATAGACAAGTTTGTACATCCAAAAACATATGCTGTCAGGAGGATAAGAGATGCCTTCAGAGAAAATAAAAATGTAAAGGATCCTGTAGAA
ATTCAAACCCTAGTGAATAAAGCCAAGAGAGACCTTGGAGTAATTCGTCGACAGGTCCACATTGGCCAACTGTATTCAACTGACAAGCTG
ATCATTGAGAATCGAGACATGCCCAGGACCTAGCAAGCCGGGGACCAGCCACCAGTGGCGGCCAGGGACCACCTTCAGCATCCACTCTCT
GTTTGAGATGGGGGCTCCCAAAACCAGCTTACAATAGCCTTTTGCGCTGCCTGTCCTGTGGGAGCTGATAAACCAAGTCACATTTGCATT
CTGTTGCAGGCTTAGTGAAAAAGGACTGCTGTCTTTCCTTGGTTCAAGTGTTAGAATGGAGAGCTGGAGTTCGTTCAGAATAGTGCTGTG
TGTTACCACGTCTCCCCTGCACCCCATTCCTACCTTGTAGCTCATGACCATTGTGTATAGCATTTCTACACTTTGTTTCTTGGTCCTTGG
CAATAAAAAGAATGATCTCCCTGAGCCTTTGACCCCAGATAAACCCCTCCCAATTAATGCATTTTCATTTCCTACTGATACAAGGCCTGG
AGAGGGCTGTTGGGGGCCCTCAGGGAGGGTTCAACTCTGAGACGAGAACTGCCTTGGTGAAGGCAAGTTCAAGCACCACTTGAGACTGGG
GGCAGCATGGAGTAGGGCAGGGCTACGGGGATACACGGTGCACCCTGCAACTTATACCTGAGCCCAGTACAACAAAGGTGACGGGTGTGT
AGGTACACACCCAGAGATGGAGCACTGCAGATCAGCAACCTCAGCCCCACCTGGGAATTTGCTGGAAATGCAGGCTCAAGCCCCTCCCCA
CACCTGGTGAATGAGAGAGCCCCAGCCTGACCCAAGCCCAGGGCGACTCCCATACCCTGAAGCCTGGGGCATGCTGGGCAGCACCGGTGC
CCAAATCTGGCTGGTGGACAGAAGCACCTGGAGAGTTGGAGAGCTTTTTAAAAAGACATCTCTCAGCACTTCCCTCTCTGCAGATTCTGA
CTCAGTAAGTGAGGGGTGAGGCACAGTCATTTTTCTCTATTCTGAAGCTCTCCCACTGTTTTCAATGTTTAACCAACTGGGGACCCCTGC
TCTTTAAGTATATTACAGGTAATAAAGATATTGTTTGTATGCTTTTATTCTTGGAAACAGATTCATTCCAAACATAGAAAGAACATATTA
AATAACTTGCTTGTCATCTGGGGAGTTTACGAGGGACCAGACCTGGCAGAGCGGTTTCTTGTTTCCCTTTGCATACAGTGCTCAGTGGAT
TTGGTATCTGTGGGTTAAGGTTTGGAACAGGCTCCTATAAATAGCACCGGTCCTGGAATAGCTGCAGCACTGTCACCCCCTCATTTTAAC
TCCGACGGTCATGGGAGTGAGTACGCACTGTCTGAGCCCGTGTTCTTCTCACCCTCATATGAGAACTCATGTCTTCCAGTCGCTTTTAGA
GAGCATAGATTTGCTGCAATGATGCGTTCAAATAGATGTAACGTGTAGCCATTCTATTTGGCAGTACAACTTTTGATTTCAGGATAAAGT
CTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGCGGTGCGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTT
CAAGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGGGCCTGCCACCACGCCCAGCTAATTTTTTGTATTTTTAATAGAG
ACGGGGTTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTCGGCCCCCCAAAGTGCTGGTATTACAGGCATGAACCACCACCCCCTGCC
AATTTCAGGATAAAGTCCTGAGCATCTGTGAAAATAATGAAGCTCTTAGCAAGTCCCAGATCTCTTACCCTCTAACCAGTTCCTGCCTGG
GAGCTGCAGTGTTAGAGCATATGCAAAGCCCTAATTGGGGGAGAGCTGTTCGGTGGACAGTGAACGGAGGTGATGTGGCAAGTATAATCA
CTCCCTTCAGCTGACTGTCACGGGGCAGAGCCGCCCAGCCCAGCCCTGTGTGTGGCTCTGGCTCAGGTTTTCCACCTTGCATCAGTGCAG
TGGAGTTCGTGGTCACTCAGCAGTGAATGCATCCAACCACGCTACTAACGCACGGCACTGCTGATTTATACTTAATTTAAGCAACTGCTA
CTTGGAACCGAAGTCCAGATTTGAACCTCCGTGCTGAAGGCATCAAATTGCCGGCAAGATAACAGCTCCAGAGGAGACTTCTCCCACTCC
CCCAGGTTTTACGCAATGAGGCAGTCCACCCAAACTTAACGTGGGCTGCAGGCTGTAACAGCAGGTTGCTTTTGTGTTCATTAAACTGCA
TGAATGGGTTTGAACATGCCCAAAGCCTTGCTAATGCAGACTTAATTTTGTAAAATTAACTATGCCTTTGGAATCTGCAGAAAGATACAA
ATCCGAATTCTGTGGCAGGAAACGCCACAAACAGGCCTTGGTCCTCCACCTTTCAGGTGTATATCTGGCAGGCAGAGCCTGGCACTGGGT
ACTCCCCAACTGAGATGACCCAATATTGATGCTAGAGCTTCGAATAAAGTGGCATTCCCATGGGGGTGACCCCTGGTGTTTCTCTAGGGA
AGTATTCCACCTCCTTGACTATGCACCAACTGAGGGGAATGTGGGCAACTCCAACATCCATCATGGCCAGCCTCACAGAACTCTCTAGAA
CTTGTGCCTGCTTTGAAGATAGGATCCGGGCTGGGGTCTGGAGATCACTTTGCAGCACTAATATTGAGCAAATGAGAACTACTATCATTA
GTTAACTTCCCAGGCAGAACTCATTGGCCGAGCAAGGCTATATCCTAGACTTTCAGAGACAGCTCTGGGCTGGGCTGGCTGTCATGACAT
AATAGCTGGGAGATCTTGCACGGCCAAGTACAGGGCTGTGTTGTTCTGATGGCTGTTGGAATCTGGATTTTGGAACTGAAAGAATTGGCT
AGATTGCTTTAGGTATACTCCGTCCTGCTGCTAACTAAGTAGCAGTGACCTTTAACTCCCTTCATCCACAGCCTCTCCCGTTAATCTCAA
GCCCCACCATACAACCCACCATCATCCAGGAGCAAAAGGGACAGGCAGAGGGTGAAGCCTACAAAGATGACAAACATCAGAGCTCACCTA
GTCCAACCCTCAAATCTTCAGGTGTTAAAACAAAGAGCCTGAACATCTGCAGATCACGTACAGAGTCAGGGCCTTTCCCCTAAACCCCTT
TCACTCATTCATTTATTCACTCAGTATTGACTAAGGCCACCTAGTGCCAGGTGCCAGGTGCCAGGGAGCAACCAGTGAACAAGACAGACG
TACCTTCATAAAGCCTGTGTCTAGCAGGGAAATCTGAGAAGAAAATGACAAGTCTTATGAATGTTACAAAGAGGGAAATATGAGTGCTGC
CAGAGCCGATGGGACGGGCCAGGGAAGGGCTCCCCAGGGGATATTTACACGTGCAAATTAATGATGAGGATTGGCTGTGTGAAGGTGGGG
AGAGGAGCTCTCTAGGCAGGAGGAACAGCACATGCAAAGCCCTTAATTGGGGGAGAGGGTAGTTCCATGCAAAGAACTAAAGGGAGTCTG
GGATGGTGGCAGCCAAGGAAGAGGGCTCTTTCCACATCGTGGACGGCCTTGGAGCCTCAGCCTAAGGATGGTGAGCAACTCGGGAGTTTT
TAGGCAAGATGAGGTTTTTGTTTTGTTTTGTTTTGTTTTTTTGAGACAGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATAAT
CTCAGCTCACTACAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCACGCCACCA
TGCCCAGCTAAGTTTTATATTTTTTAGTAGACACAGGATTTCGCCATGTTGGCCAGGCTGCTCTTGAACTCCTGACCCCAGATGATCCGC
CTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCCCCCGACCGAAGTTTGTATTTTTTAAAAGGTCACATTGTCTGC
TTTTGAGGGGATACACTGGGAGAGATGCAGGGAGACCAGCTTTTCGGAGGAGTGGGGGATTGGGTGTGGCATTCCAGGCAAGCGATGGTG
ACTTCACCAAGAGGCAACAGCTGAACAGAAGCAGAGTCAGCATCACCCTGAGAACTGGCTGGGGTGGGCCGCCATTGAAGGAGGACAGGA
AACCTGGAGCAGAGCTGCCCCAGCTGAGCACAGCCCGAGCTCCCCAGCCCACCTGCCGATGCGCGAGAAAGTCCACAGAGTCCCCTAGCC
TGGTCTAGCTTAGGTCAGTCATATTCAGCCACCCCTCAGACATGTGCTAAATAATTAACTGTTACATTAGTCACTGAGTTTGGAGGTAGA
TTATTATGAAGTAACAGCAAACTAATACAGAGAGCATCTCTGTATTAATGTATTAATGTATTACTTTCTCAGGGCCACATAGCAAACCAA
AGAGTAGGCAGACAAACGGCCAAAACTGCAGGTCTCCTGTATGGGGACATTTCCACAAATATCTTCAGAATACTGGTCACTCCCTTTAGA
GAACAAGTCCTGGAGAAACAGTCGAAACAGTCATCACGTGTCCTACAGATGGAAGGGCTGGCCAACCAGAAAGAAAAGAAAAAGTCGAGT
CAGCAGAACTTGGTGATTGATTGGATGAGGAGACCAGGCCTGAGGGCTGCAGGGAGTCTAGGAGGAGTCTCAGGAGCAGGGCCTGAGGAA
CTAAGAAGGGGCTCTGGCTGAGACCAGACAGGAGCAGCCACTGTCTGGAATTTTGTCCCCACTGCTGACTTCGAACAACCTCAACTTCAA
ACAGAAAGCCCAGACTCGATGAATTTATCTTTTCTTCAAAGTAGAGAAAGGGTAGCTCTTTTCTTCCCAGGAAATTGTTTATCCATTTAA
TAATTTTTAAAAATCACTGGAGTTGGGTGTGGTGGCTCATACCTGGTAATCTCAGCACTTTGAGAGGCCGAAGTGGGCAGATCACTTGAG
CTCAGGAGTTCGAGACCAGCCTGGGCAACATAGTGAAACCCTGTCTATACAGAAAATACAAAAATTAGCTGGGTGTGGTGGCATGCAACT
GTTGTCCTAGCTACTCTGGAGCCTGAGGTGGGAGGATCACTTGAGCCTGGAAGGCGGAGGTTGCAGTGAGCCATGATCGCACCACTGCAC
TCCAGCCTGGATGACAGAGTGATACCCTGTCTAAAAAAAAAAAAATAACTGGGATAAAACAACTCGAAAGACCCTTATAAAGATTTTACC
CGTAACTCTGTAGAGCAAATAACTTCCTGCTTTAGGCAAAGCTCTTTGTGTGTAAGTTCGATTGGAAGAGGAGGGCTGGTGGGGGGAGAT
TCTCTACTTTGGTCATGAGATTAACATTAAAAGTTTGAGGAAGGTTGCTCTATATATTGGCTGCCTGTTTCTAAGACTGAAAATAAAAGC
ACAGTAAAATATCAACAAGTATACAGAAAATATACATTTGTAGAAAATTAGCTTTTTTTTTTTTTTTTGCTAAGTACTTCATATAAACTA
GTATTTGCTTTCTAGATTAAAGAATATCTCCTCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAAGCCGAGGTGGATGGA
CCACGATGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTCCTAAAGATACAAAAAAAATTAGCCAGGCGTGGCA
GTGGGCGCCTGTAATCCCAGCTACTCAGGAGACTGAGGCAGAGAATTGCTTGAAGCCAGAGGCAGAGGTTGCAATGAGCCGGGATCACGC
CACTGAACTCCAGCCTGGGTGACAGAGTGAGACTCTTGTCTCAAAAAAAAAAAAAAAAAAAAAAATATCTCAGATATTGAAGCGAACCTA
TAAATAACAGCAGAAGCTGAAGAAAAGATAACGGATCAAAAAGCAGAAGGAGAAAGCTTCCCTGTCCCCAAGGACCTGCCCACAGTCGTG
GATGAGAAGTCCCTTGATAAGTAGGGTCTGAACCCACGTGATCAAATGTTAGCTCTGTGAACCTGTGCCAGTGGCTGTGTGTCAGTAGCC
CAGGGTGATTCAGAAGCTCCATGAAGCAGCCATCTTTCCTGGATCTCTGGAATGTACACATTTGCTGAGATCACAAAGATGAAGCTGGCA
GAACCCGAGTGGATATTCATTATTACGAACAGAAGAACAGCCAACAGGAGCCGTGCCATGTGCAACCCCGAGTTGACAGATGCCTCCCCG
CTTCTTCTGTGTTTGCCAGTTGTTACAAAATGATCTAGAGAAAAACTGGAACTTGATGGAGAAAGCAATGGCTTACGATTCAGCAGGCTT
TCTTGGAGAGTTTACCTAAAGTCTATGTGGACGGTGGCTCAGCTCACCTCTGAGAACAATACGATCTTCACTTTTCAATCTTTCTGCAGC
TCTAATTAGTGCCACAGGGAACCATGGATGAAAATGGCTTCTCGTGTTGATATCCATTTGGGGAATAGGATGGATGCAGCTGCTTTTGCT
CAAGGGCAGAGTTTTGACTTCAAAGACCCTGAAGAGAACCCAGAAGGAAAACTCTCAGAGGTCAATGGACTATATTCTTTACCTGGGGGA
TCGTTGACACCACAGCAGTAAAAGCGAAGTCAGTGTCGTGCTGTCTTGAAATTAGATGACAAGAATGACTGACACCAATAGAGCTGGAAC
TGCACTTGGAGCCTGAGTAGCCGGTCTCAGGCTAACCACACCTGTGCTGACCACAGCGTGGCCCGTGTTGTTCATGAGGCATTCTGGCTG
TACCTCCACAGGGATGCAAGACTTCCAGTGAGAGGCTGCTTCTGCAAGAAAATACCTGCCTAGAAATGGTCCGCTTTCTCTTCCTAATAA

>29404_29404_2_FARS2-LYRM4_FARS2_chr6_5613553_ENST00000324331_LYRM4_chr6_5216971_ENST00000330636_length(amino acids)=468AA_BP=406
MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIK
ERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRR
DQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPF
THPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKY
PAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FARS2-LYRM4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FARS2-LYRM4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FARS2-LYRM4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource