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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FBXL20-GSDMB (FusionGDB2 ID:29650)

Fusion Gene Summary for FBXL20-GSDMB

check button Fusion gene summary
Fusion gene informationFusion gene name: FBXL20-GSDMB
Fusion gene ID: 29650
HgeneTgene
Gene symbol

FBXL20

GSDMB

Gene ID

84961

55876

Gene nameF-box and leucine rich repeat protein 20gasdermin B
SynonymsFbl2|Fbl20GSDMB-1|GSDML|PP4052|PRO2521
Cytomap

17q12

17q21.1

Type of geneprotein-codingprotein-coding
DescriptionF-box/LRR-repeat protein 20F-box protein FBL2gasdermin-Bgasdermin-like proteingasderminB-1
Modification date2020031320200313
UniProtAcc

Q96IG2

Q8TAX9

Ensembl transtripts involved in fusion geneENST00000264658, ENST00000394294, 
ENST00000577399, ENST00000583610, 
ENST00000309481, ENST00000394175, 
ENST00000394179, ENST00000418519, 
ENST00000520542, ENST00000360317, 
Fusion gene scores* DoF score58 X 21 X 16=1948812 X 13 X 9=1404
# samples 6115
** MAII scorelog2(61/19488*10)=-4.99763298545608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1404*10)=-3.22650852980868
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FBXL20 [Title/Abstract] AND GSDMB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFBXL20(37557614)-GSDMB(38068750), # samples:5
Anticipated loss of major functional domain due to fusion event.FBXL20-GSDMB seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across FBXL20 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GSDMB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-22-0944-01AFBXL20chr17

37557614

-GSDMBchr17

38068750

-
ChimerDB4LUSCTCGA-22-0944FBXL20chr17

37557614

-GSDMBchr17

38068750

-
ChimerDB4LUSCTCGA-22-0944FBXL20chr17

37558426

-GSDMBchr17

38073574

-
ChimerDB4LUSCTCGA-22-0944FBXL20chr17

37558426

-GSDMBchr17

38073583

-
ChimerDB4STADTCGA-BR-8060-01AFBXL20chr17

37557614

-GSDMBchr17

38068750

-
ChimerDB4UCECTCGA-B5-A5OE-01AFBXL20chr17

37499433

-GSDMBchr17

38068750

-
ChimerDB4UCECTCGA-B5-A5OE-01AFBXL20chr17

37499433

-GSDMBchr17

38073574

-


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Fusion Gene ORF analysis for FBXL20-GSDMB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000264658ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000264658ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000264658ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000264658ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000264658ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000394294ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000394294ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000394294ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000394294ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000394294ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073583

-
5CDS-5UTRENST00000577399ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073583

-
5CDS-5UTRENST00000577399ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073583

-
5CDS-5UTRENST00000577399ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073583

-
5CDS-5UTRENST00000577399ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000577399ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000583610ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000583610ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000583610ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000583610ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-5UTRENST00000583610ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38073574

-
5CDS-intronENST00000577399ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073583

-
5CDS-intronENST00000577399ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073583

-
Frame-shiftENST00000264658ENST00000309481FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000360317FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38073574

-
Frame-shiftENST00000264658ENST00000394175FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000394179FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000418519FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000520542FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000264658ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000309481FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000360317FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38073574

-
Frame-shiftENST00000394294ENST00000394175FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000394179FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000418519FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000520542FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000394294ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000577399ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000577399ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000577399ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38073574

-
Frame-shiftENST00000577399ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000577399ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000577399ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000577399ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000309481FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000309481FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000360317FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000394175FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000394175FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000394179FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000394179FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000418519FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000418519FBXL20chr17

37499433

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000520542FBXL20chr17

37557614

-GSDMBchr17

38068750

-
Frame-shiftENST00000583610ENST00000520542FBXL20chr17

37499433

-GSDMBchr17

38068750

-
In-frameENST00000577399ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073574

-
In-frameENST00000583610ENST00000360317FBXL20chr17

37499433

-GSDMBchr17

38073574

-
intron-3CDSENST00000264658ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-3CDSENST00000394294ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-3CDSENST00000577399ENST00000309481FBXL20chr17

37557614

-GSDMBchr17

38068750

-
intron-3CDSENST00000577399ENST00000360317FBXL20chr17

37557614

-GSDMBchr17

38068750

-
intron-3CDSENST00000577399ENST00000394175FBXL20chr17

37557614

-GSDMBchr17

38068750

-
intron-3CDSENST00000577399ENST00000394179FBXL20chr17

37557614

-GSDMBchr17

38068750

-
intron-3CDSENST00000577399ENST00000418519FBXL20chr17

37557614

-GSDMBchr17

38068750

-
intron-3CDSENST00000577399ENST00000520542FBXL20chr17

37557614

-GSDMBchr17

38068750

-
intron-3CDSENST00000583610ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000264658ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000264658ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000264658ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000264658ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000264658ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000264658ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000264658ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000264658ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000264658ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000394294ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000394294ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000394294ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000394294ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000394294ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000394294ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000394294ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000394294ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000394294ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000583610ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000583610ENST00000309481FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000583610ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000583610ENST00000394175FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000583610ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000583610ENST00000394179FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000583610ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-5UTRENST00000583610ENST00000418519FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-5UTRENST00000583610ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073574

-
intron-intronENST00000264658ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-intronENST00000264658ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-intronENST00000394294ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-intronENST00000394294ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-intronENST00000583610ENST00000360317FBXL20chr17

37558426

-GSDMBchr17

38073583

-
intron-intronENST00000583610ENST00000520542FBXL20chr17

37558426

-GSDMBchr17

38073583

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000583610FBXL20chr1737499433-ENST00000360317GSDMBchr1738073574-18263583581608416
ENST00000577399FBXL20chr1737558426-ENST00000360317GSDMBchr1738073574-18193511981601467

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000583610ENST00000360317FBXL20chr1737499433-GSDMBchr1738073574-0.0020737770.99792624
ENST00000577399ENST00000360317FBXL20chr1737558426-GSDMBchr1738073574-0.0058702480.9941298

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Fusion Genomic Features for FBXL20-GSDMB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FBXL20-GSDMB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:37557614/chr17:38068750)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FBXL20

Q96IG2

GSDMB

Q8TAX9

FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission (By similarity). {ECO:0000250}.FUNCTION: [Gasdermin-B]: Precursor of a pore-forming protein that acts as a downstream mediator of granzyme-mediated cell death (PubMed:32299851). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-B, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:32299851). {ECO:0000269|PubMed:32299851}.; FUNCTION: [Gasdermin-B, N-terminal]: Pore-forming protein produced by cleavage by granzyme A (GZMA), which causes membrane permeabilization and pyroptosis in target cells of cytotoxic T and natural killer (NK) cells (PubMed:27281216, PubMed:32299851). Key downstream mediator of granzyme-mediated cell death: (1) granzyme A (GZMA), delivered to target cells from cytotoxic T- and NK-cells, (2) specifically cleaves Gasdermin-B to generate this form (PubMed:32299851). After cleavage, moves to the plasma membrane, homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (PubMed:32299851). Binds to membrane inner leaflet lipids, such as phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, bisphosphorylated phosphatidylinositols, such as phosphatidylinositol (4,5)-bisphosphate, and more weakly to phosphatidic acid (PubMed:28154144). Also binds sufatide, a component of the apical membrane of epithelial cells (PubMed:28154144). {ECO:0000269|PubMed:27281216, ECO:0000269|PubMed:28154144, ECO:0000269|PubMed:32299851}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGSDMBchr17:37499433chr17:38073574ENST00000309481010243_2710404.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37499433chr17:38073574ENST00000360317-110243_27178417.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37499433chr17:38073574ENST0000039417508243_2710395.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37499433chr17:38073574ENST00000394179010243_2710412.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37499433chr17:38073574ENST00000418519011243_2710417.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37499433chr17:38073574ENST00000520542010243_2710408.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37558426chr17:38073574ENST00000309481010243_2710404.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37558426chr17:38073574ENST00000360317-110243_27178417.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37558426chr17:38073574ENST0000039417508243_2710395.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37558426chr17:38073574ENST00000394179010243_2710412.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37558426chr17:38073574ENST00000418519011243_2710417.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37558426chr17:38073574ENST00000520542010243_2710408.0Coiled coilOntology_term=ECO:0000255
TgeneGSDMBchr17:37499433chr17:38073574ENST000003094810101_2750404.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37499433chr17:38073574ENST00000394175081_2750395.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37499433chr17:38073574ENST000003941790101_2750412.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37499433chr17:38073574ENST000004185190111_2750417.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37499433chr17:38073574ENST000005205420101_2750408.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37558426chr17:38073574ENST000003094810101_2750404.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37558426chr17:38073574ENST00000394175081_2750395.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37558426chr17:38073574ENST000003941790101_2750412.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37558426chr17:38073574ENST000004185190111_2750417.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37558426chr17:38073574ENST000005205420101_2750408.0RegionTriggers pyroptosis

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-21522_6834437.0DomainF-box
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-21422_6834405.0DomainF-box
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-21622_6834411.6666666666667DomainF-box
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-11522_680437.0DomainF-box
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-11422_680405.0DomainF-box
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-11622_680411.6666666666667DomainF-box
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215101_12634437.0RepeatNote=LRR 2
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215127_15234437.0RepeatNote=LRR 3
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215153_17834437.0RepeatNote=LRR 4
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215179_20434437.0RepeatNote=LRR 5
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215205_23034437.0RepeatNote=LRR 6
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215231_25634437.0RepeatNote=LRR 7
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215257_28234437.0RepeatNote=LRR 8
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215283_30834437.0RepeatNote=LRR 9
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215309_33434437.0RepeatNote=LRR 10
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215335_36334437.0RepeatNote=LRR 11
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215364_38834437.0RepeatNote=LRR 12
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-215389_41434437.0RepeatNote=LRR 13
HgeneFBXL20chr17:37499433chr17:38073574ENST00000264658-21574_10034437.0RepeatNote=LRR 1
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214101_12634405.0RepeatNote=LRR 2
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214127_15234405.0RepeatNote=LRR 3
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214153_17834405.0RepeatNote=LRR 4
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214179_20434405.0RepeatNote=LRR 5
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214205_23034405.0RepeatNote=LRR 6
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214231_25634405.0RepeatNote=LRR 7
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214257_28234405.0RepeatNote=LRR 8
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214283_30834405.0RepeatNote=LRR 9
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214309_33434405.0RepeatNote=LRR 10
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214335_36334405.0RepeatNote=LRR 11
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214364_38834405.0RepeatNote=LRR 12
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-214389_41434405.0RepeatNote=LRR 13
HgeneFBXL20chr17:37499433chr17:38073574ENST00000394294-21474_10034405.0RepeatNote=LRR 1
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216101_12634411.6666666666667RepeatNote=LRR 2
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216127_15234411.6666666666667RepeatNote=LRR 3
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216153_17834411.6666666666667RepeatNote=LRR 4
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216179_20434411.6666666666667RepeatNote=LRR 5
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216205_23034411.6666666666667RepeatNote=LRR 6
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216231_25634411.6666666666667RepeatNote=LRR 7
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216257_28234411.6666666666667RepeatNote=LRR 8
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216283_30834411.6666666666667RepeatNote=LRR 9
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216309_33434411.6666666666667RepeatNote=LRR 10
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216335_36334411.6666666666667RepeatNote=LRR 11
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216364_38834411.6666666666667RepeatNote=LRR 12
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-216389_41434411.6666666666667RepeatNote=LRR 13
HgeneFBXL20chr17:37499433chr17:38073574ENST00000583610-21674_10034411.6666666666667RepeatNote=LRR 1
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115101_1260437.0RepeatNote=LRR 2
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115127_1520437.0RepeatNote=LRR 3
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115153_1780437.0RepeatNote=LRR 4
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115179_2040437.0RepeatNote=LRR 5
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115205_2300437.0RepeatNote=LRR 6
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115231_2560437.0RepeatNote=LRR 7
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115257_2820437.0RepeatNote=LRR 8
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115283_3080437.0RepeatNote=LRR 9
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115309_3340437.0RepeatNote=LRR 10
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115335_3630437.0RepeatNote=LRR 11
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115364_3880437.0RepeatNote=LRR 12
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-115389_4140437.0RepeatNote=LRR 13
HgeneFBXL20chr17:37558426chr17:38073574ENST00000264658-11574_1000437.0RepeatNote=LRR 1
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114101_1260405.0RepeatNote=LRR 2
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114127_1520405.0RepeatNote=LRR 3
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114153_1780405.0RepeatNote=LRR 4
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114179_2040405.0RepeatNote=LRR 5
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114205_2300405.0RepeatNote=LRR 6
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114231_2560405.0RepeatNote=LRR 7
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114257_2820405.0RepeatNote=LRR 8
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114283_3080405.0RepeatNote=LRR 9
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114309_3340405.0RepeatNote=LRR 10
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114335_3630405.0RepeatNote=LRR 11
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114364_3880405.0RepeatNote=LRR 12
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-114389_4140405.0RepeatNote=LRR 13
HgeneFBXL20chr17:37558426chr17:38073574ENST00000394294-11474_1000405.0RepeatNote=LRR 1
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116101_1260411.6666666666667RepeatNote=LRR 2
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116127_1520411.6666666666667RepeatNote=LRR 3
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116153_1780411.6666666666667RepeatNote=LRR 4
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116179_2040411.6666666666667RepeatNote=LRR 5
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116205_2300411.6666666666667RepeatNote=LRR 6
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116231_2560411.6666666666667RepeatNote=LRR 7
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116257_2820411.6666666666667RepeatNote=LRR 8
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116283_3080411.6666666666667RepeatNote=LRR 9
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116309_3340411.6666666666667RepeatNote=LRR 10
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116335_3630411.6666666666667RepeatNote=LRR 11
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116364_3880411.6666666666667RepeatNote=LRR 12
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-116389_4140411.6666666666667RepeatNote=LRR 13
HgeneFBXL20chr17:37558426chr17:38073574ENST00000583610-11674_1000411.6666666666667RepeatNote=LRR 1
TgeneGSDMBchr17:37499433chr17:38073574ENST00000360317-1101_27578417.0RegionTriggers pyroptosis
TgeneGSDMBchr17:37558426chr17:38073574ENST00000360317-1101_27578417.0RegionTriggers pyroptosis


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Fusion Gene Sequence for FBXL20-GSDMB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>29650_29650_1_FBXL20-GSDMB_FBXL20_chr17_37499433_ENST00000583610_GSDMB_chr17_38073574_ENST00000360317_length(transcript)=1826nt_BP=358nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTG
GAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCC
GGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGA
ACGGAGTGACCAAGAGCAGGTTTGAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGAT
GTTCAGCGTATTTGAGGAAATCACAAGAATTGTAGTTAAGGAGATGGATGCTGGAGGGGATATGATTGCCGTTAGAAGCCTTGTTGATGC
TGATAGATTCCGCTGCTTCCATCTGGTGGGGGAGAAGAGAACTTTCTTTGGATGCCGGCACTACACAACAGGCCTCACCCTGATGGACAT
TCTGGACACAGATGGGGACAAGTGGTTAGATGAACTGGATTCTGGGCTCCAAGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGA
CTCAACGGGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATC
GGAGAACCGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATAC
GAGAGAAAACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCA
GATCTCTCAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCA
GCTTGTCTTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTG
TTTAGGAAAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGA
GAAGAGAAAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCT
GATTTCCGGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGC
AAAAGCCATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCC
TCTGTTGAAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGC
ACGAATTCTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCC
CTTTCTCCCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTT
AAAACAAGCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGAT

>29650_29650_1_FBXL20-GSDMB_FBXL20_chr17_37499433_ENST00000583610_GSDMB_chr17_38073574_ENST00000360317_length(amino acids)=416AA_BP=0
MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNV
DSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS
QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTE
EKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTL

--------------------------------------------------------------
>29650_29650_2_FBXL20-GSDMB_FBXL20_chr17_37558426_ENST00000577399_GSDMB_chr17_38073574_ENST00000360317_length(transcript)=1819nt_BP=351nt
GCCAAAGGAAGGGTTGCCCGGCTCCAGCCCTGCACCCCCGACCCCCGGCCTCAGGTGCAGCTCCGCAGCCATCCCCGGACCAGGGCGGGC
ACTTGGCCTGTTGCTCAGCGCAACCACCCTCGCCCTCCCGAGCCATGCACAGGGAGACAAGCGTCCGGCCCCGGCCCCCCAGGCCTCCCT
GCAGCACCCCGTAATGTAATGCACTGGGGCGGGGGAGGCGGGGGAGGCGGCGGCGGCGGCAACCGCGGAGGCGCGGCGGCAGCCGCACTG
CCCCAATCTAGACACATCCAGAAGAGGAGGAAAATGGCTCCGAGCAGGGACCGCCTGCTGCACTTTGGGTTCAAGGCGACAATGTTCAGC
GTATTTGAGGAAATCACAAGAATTGTAGTTAAGGAGATGGATGCTGGAGGGGATATGATTGCCGTTAGAAGCCTTGTTGATGCTGATAGA
TTCCGCTGCTTCCATCTGGTGGGGGAGAAGAGAACTTTCTTTGGATGCCGGCACTACACAACAGGCCTCACCCTGATGGACATTCTGGAC
ACAGATGGGGACAAGTGGTTAGATGAACTGGATTCTGGGCTCCAAGGTCAAAAGGCTGAGTTTCAAATTCTGGATAATGTAGACTCAACG
GGAGAGTTGATAGTGAGATTACCCAAAGAAATAACAATTTCAGGCAGTTTCCAGGGCTTCCACCATCAGAAAATCAAGATATCGGAGAAC
CGGATATCCCAGCAGTATCTGGCTACCCTTGAAAACAGGAAGCTGAAGAGGGAACTACCCTTTTCATTCCGATCAATTAATACGAGAGAA
AACCTGTATCTGGTGACAGAAACTCTGGAGACGGTAAAGGAGGAAACCCTGAAAAGCGACCGGCAATATAAATTTTGGAGCCAGATCTCT
CAGGGCCATCTCAGCTATAAACACAAGGGCCAAAGGGAAGTGACCATCCCCCCAAATCGGGTCCTGAGCTATCGAGTAAAGCAGCTTGTC
TTCCCCAACAAGGAGACGATGAATATTCATTTCAGGGGCAAAACAAAATCCTTTCCAGAAGAGAAGGATGGTGCTTCATCCTGTTTAGGA
AAGTCTTTGGGTTCGGAGGATTCCAGAAACATGAAGGAGAAGTTGGAGGACATGGAGAGTGTCCTCAAGGACCTGACAGAGGAGAAGAGA
AAAGATGTGCTAAACTCCCTCGCTAAGTGCCTCGGCAAGGAGGATATTCGGCAGGATCTAGAGCAAAGAGTATCTGAGGTCCTGATTTCC
GGGGAGCTACACATGGAGGACCCAGACAAGCCTCTCCTAAGCAGCCTTTTTAATGCTGCTGGGGTCTTGGTAGAAGCGCGTGCAAAAGCC
ATTCTGGACTTCCTGGATGCCCTGCTAGAGCTGTCTGAAGAGCAGCAGTTTGTGGCTGAGGCCCTGGAGAAGGGGACCCTTCCTCTGTTG
AAGGACCAGGTGAAATCTGTCATGGAGCAGAACTGGGATGAGCTGGCCAGCAGTCCTCCTGACATGGACTATGACCCTGAGGCACGAATT
CTCTGTGCGCTGTATGTTGTTGTCTCTATCCTGCTGGAGCTGGCTGAGGGGCCTACCTCTGTCTCTTCCTAACTACAAAAGCCCTTTCTC
CCCACAAGCCTCTGGGTTTTCCCTTTACCAGTCTGTCCTCACTGCCATCGCCACTACCATCCTGTCACCAGTGGGACCTCTTTAAAACAA
GCAGCCAACCATTCTTTGATGTATCCCATTCGCTCCATGTTAACATCCAAAACCAGCCTGGATTTCATACATGGACTTCTGATTAAAAGT

>29650_29650_2_FBXL20-GSDMB_FBXL20_chr17_37558426_ENST00000577399_GSDMB_chr17_38073574_ENST00000360317_length(amino acids)=467AA_BP=51
MHWGGGGGGGGGGGNRGGAAAAALPQSRHIQKRRKMAPSRDRLLHFGFKATMFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHL
VGEKRTFFGCRHYTTGLTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQY
LATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKET
MNIHFRGKTKSFPEEKDGASSCLGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHME
DPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FBXL20-GSDMB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FBXL20-GSDMB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FBXL20-GSDMB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource