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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:FBXL20-PIP4K2B (FusionGDB2 ID:29665)

Fusion Gene Summary for FBXL20-PIP4K2B

Fusion gene summary

Fusion gene information	Fusion gene name: FBXL20-PIP4K2B
	Fusion gene ID: 29665
		Hgene	Tgene
	Gene symbol	FBXL20	PIP4K2B
	Gene ID	84961	8396
	Gene name	F-box and leucine rich repeat protein 20	phosphatidylinositol-5-phosphate 4-kinase type 2 beta
	Synonyms	Fbl2\|Fbl20	PI5P4KB\|PIP5K2B\|PIP5KIIB\|PIP5KIIbeta\|PIP5P4KB
	Cytomap	17q12	17q12
	Type of gene	protein-coding	protein-coding
	Description	F-box/LRR-repeat protein 20F-box protein FBL2	phosphatidylinositol 5-phosphate 4-kinase type-2 beta1-phosphatidylinositol 5-phosphate 4-kinase 2-beta1-phosphatidylinositol-4-phosphate kinasePI(5)P 4-kinase type II betaPIP4KII-betaPTDINS(4)P-5-kinasediphosphoinositide kinase 2-betaphosphatidyli
	Modification date	20200313	20200313
	UniProtAcc	Q96IG2	.
	Ensembl transtripts involved in fusion gene	ENST00000264658, ENST00000394294, ENST00000583610, ENST00000577399,	ENST00000311500, ENST00000269554,
Fusion gene scores	* DoF score	58 X 21 X 16=19488	15 X 14 X 6=1260
	# samples	61	20
	** MAII score	log2(61/19488*10)=-4.99763298545608 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(20/1260*10)=-2.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: FBXL20 [Title/Abstract] AND PIP4K2B [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	PIP4K2B(36955519)-FBXL20(37499494), # samples:2 FBXL20(37557614)-PIP4K2B(36927525), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across FBXL20 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PIP4K2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-AR-A1AT-01A	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-

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Fusion Gene ORF analysis for FBXL20-PIP4K2B

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000264658	ENST00000311500	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-
5CDS-intron	ENST00000394294	ENST00000311500	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-
5CDS-intron	ENST00000583610	ENST00000311500	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-
In-frame	ENST00000264658	ENST00000269554	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-
In-frame	ENST00000394294	ENST00000269554	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-
In-frame	ENST00000583610	ENST00000269554	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-
intron-3CDS	ENST00000577399	ENST00000269554	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-
intron-intron	ENST00000577399	ENST00000311500	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000583610	FBXL20	chr17	37557614	-	ENST00000269554	PIP4K2B	chr17	36927525	-	4742	296	254	739	161
ENST00000394294	FBXL20	chr17	37557614	-	ENST00000269554	PIP4K2B	chr17	36927525	-	4709	263	221	706	161
ENST00000264658	FBXL20	chr17	37557614	-	ENST00000269554	PIP4K2B	chr17	36927525	-	4749	303	261	746	161

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000583610	ENST00000269554	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-	0.00298617	0.9970138
ENST00000394294	ENST00000269554	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-	0.003009206	0.9969908
ENST00000264658	ENST00000269554	FBXL20	chr17	37557614	-	PIP4K2B	chr17	36927525	-	0.002998332	0.9970017

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Fusion Genomic Features for FBXL20-PIP4K2B

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FBXL20-PIP4K2B

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:36955519/chr17:37499494)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
FBXL20 Q96IG2	.
FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

22_68

437.0

Domain

F-box

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

22_68

405.0

Domain

F-box

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

22_68

411.6666666666667

Domain

F-box

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

101_126

437.0

Repeat

Note=LRR 2

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

127_152

437.0

Repeat

Note=LRR 3

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

153_178

437.0

Repeat

Note=LRR 4

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

179_204

437.0

Repeat

Note=LRR 5

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

205_230

437.0

Repeat

Note=LRR 6

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

231_256

437.0

Repeat

Note=LRR 7

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

257_282

437.0

Repeat

Note=LRR 8

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

283_308

437.0

Repeat

Note=LRR 9

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

309_334

437.0

Repeat

Note=LRR 10

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

335_363

437.0

Repeat

Note=LRR 11

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

364_388

437.0

Repeat

Note=LRR 12

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

389_414

437.0

Repeat

Note=LRR 13

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000264658

74_100

437.0

Repeat

Note=LRR 1

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

101_126

405.0

Repeat

Note=LRR 2

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

127_152

405.0

Repeat

Note=LRR 3

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

153_178

405.0

Repeat

Note=LRR 4

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

179_204

405.0

Repeat

Note=LRR 5

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

205_230

405.0

Repeat

Note=LRR 6

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

231_256

405.0

Repeat

Note=LRR 7

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

257_282

405.0

Repeat

Note=LRR 8

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

283_308

405.0

Repeat

Note=LRR 9

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

309_334

405.0

Repeat

Note=LRR 10

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

335_363

405.0

Repeat

Note=LRR 11

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

364_388

405.0

Repeat

Note=LRR 12

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

389_414

405.0

Repeat

Note=LRR 13

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000394294

74_100

405.0

Repeat

Note=LRR 1

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

101_126

411.6666666666667

Repeat

Note=LRR 2

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

127_152

411.6666666666667

Repeat

Note=LRR 3

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

153_178

411.6666666666667

Repeat

Note=LRR 4

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

179_204

411.6666666666667

Repeat

Note=LRR 5

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

205_230

411.6666666666667

Repeat

Note=LRR 6

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

231_256

411.6666666666667

Repeat

Note=LRR 7

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

257_282

411.6666666666667

Repeat

Note=LRR 8

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

283_308

411.6666666666667

Repeat

Note=LRR 9

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

309_334

411.6666666666667

Repeat

Note=LRR 10

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

335_363

411.6666666666667

Repeat

Note=LRR 11

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

364_388

411.6666666666667

Repeat

Note=LRR 12

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

389_414

411.6666666666667

Repeat

Note=LRR 13

Hgene

FBXL20

chr17:37557614

chr17:36927525

ENST00000583610

74_100

411.6666666666667

Repeat

Note=LRR 1

Tgene

PIP4K2B

chr17:37557614

chr17:36927525

ENST00000269554

38_415

269

417.0

Domain

PIPK

Tgene

PIP4K2B

chr17:37557614

chr17:36927525

ENST00000269554

201_204

269

417.0

Nucleotide binding

ATP or GTP

Tgene

PIP4K2B

chr17:37557614

chr17:36927525

ENST00000269554

214_216

269

417.0

Nucleotide binding

ATP or GTP

Tgene

PIP4K2B

chr17:37557614

chr17:36927525

ENST00000269554

96_98

269

417.0

Nucleotide binding

ATP or GTP

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Fusion Gene Sequence for FBXL20-PIP4K2B

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>29665_29665_1_FBXL20-PIP4K2B_FBXL20_chr17_37557614_ENST00000264658_PIP4K2B_chr17_36927525_ENST00000269554_length(transcript)=4749nt_BP=303nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGA
GGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGG
AACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGG
GACGTGAACGGAGTGACCAAGAGCAGGTTTGAGTTCTTGGCACAGCTGAAGATCATGGACTACAGCCTGCTGGTGGGCATCCACGACGTG
GACCGGGCAGAGCAGGAGGAGATGGAGGTGGAGGAGCGGGCAGAGGACGAGGAGTGTGAGAATGATGGGGTGGGTGGCAACCTACTCTGC
TCCTATGGCACACCTCCGGACAGCCCTGGCAACCTCCTCAGCTTTCCTCGGTTCTTTGGTCCTGGGGAATTCGACCCCTCTGTTGACGTC
TATGCCATGAAAAGCCATGAAAGTTCCCCCAAGAAGGAGGTGTATTTCATGGCCATCATTGATATCCTCACGCCATACGATACAAAGAAG
AAAGCTGCACATGCTGCCAAAACGGTGAAACACGGGGCAGGGGCCGAGATCTCGACTGTGAACCCTGAGCAGTACTCCAAACGCTTCAAC
GAGTTTATGTCCAACATCCTGACGTAGTTCTCTTCTACCTTCAGCCAGAGCCAGAGAGCTGGATATGGGGTCGGGGATCGGGAGTTAGGG
AGAAGGGTGTATTTGGGCTAGATGGGAGGGTGGGAGCAGAGTCGGGTTTGGGAGGGCTTTAGCAATGAGACTGCAGCCTGTGACACCGAA
AGAGACTTTAGCTGAAGAGGAGGGGGATGTGCTGTGTGTGCACCTGCTCACAGGATGTAACCCCACCTTCTGCTTACCCTTGATTTTTTC
TCCCCATTTGACACCCAGGTTAAAAAGGGGTTCCCTTTTTGGTACCTTGTAACCTTTTAAGATACCTTGGGGCTAGAGATGACTTCGTGG
GTTTATTTGGGTTTTGTTTCTGAAATTTCATTGCTCCAGGTTTGCTATTTATAATCATATTTCATCAGCCTACCCACCCTCCCCATCTTT
GCTGAGCTCTCAGTTCCCTTCAATTAAAGAGATACCCGGTAGACCCAGCACAAGGGTCCTTCCAGAACCAAGTGCTATGGATGCCAGATT
GGAGAGGTCAGACACCTCGCCCTGCTGCATTTGCTCTTGTCTGGATTAACTTTGTAATTTATGGAGTATTGTGCACAACTTCCTCCACCT
TTCCCTTGGATTCAAGTGAAAACTGTTGCATTATTCCTCCATCCTGTCTGGAATACACCAGGTCAACACCAGAGATCTCAGATCAGAATC
AGAGATCTCAGAGGGGAATAAGTTCATCCTCATGGGATGGTGAGGGGCAGGAAAGCGGCTGGGCTCTTGGACACCTGGTTCTCAGAGAAC
CCTGTGATGATCACCCAAGCCCCAGGCTGTCTTAGCCCCTGGAGTTCAGAAGTCCTCTCTGTAAAGCCTGCCTCCCACTAGGTCAAGAGG
AACTAGAGTACCTTTGGATTTATCAGGACCCTCATGTTTAAATGGTTATTTCCCTTTGGGAAAACTTCAGAAACTGATGTATCAAATGAG
GCCCTGTGCCCTCGATCTATTTCCTTCTTCCTTCTGACCTCCTCCCAGGCACTCTTACTTCTAGCCGAACTCTTAGCTCTGGGCAGATCT
CCAAGCGCCTGGAGTGCTTTTTAGCAGAGACACCTCGTTAAGCTCCGGGATGACCTTGTAGGAGATCTGTCTCCCTGTGCCTGGAGAGTT
ACAGCCAGCAAGGTGCCCCCATCTTAGAGTGTGGTGTCCAAACGTGAGGTGGCTTCCTAGTTACATGAGGATGTGATCCAGGAAATCCAG
TTTGGAGGCTTGATGTGGGTTTTGACCTGGCCTCAGCCTTGGGGCTGTTTTTCCTTGTTGCCCCGCTCTAGACTTTTAGCAGATCTGCAG
CCCACAGGCTTTTTTGGAAGGAGTGGCTTCCTGCAGGTGTTCCACCTGCCTTCGGAGCCTGCCACCCAGGCCCTCAGAACTGAGCCACAG
GCTGCTCTGGCCAGGAGAGAAACAGCTCTGTTGTTCTGCATTGGGGGAGGTACATTCCTGCATCTTCTCACCCCCTCAACCAGGAACTGG
GGATTTGGGATGAGATATGGTCAGACTTGTAGATAACCCCAAAGATGTGAAGATCGCTTGTGAAACCATTTTGAATGAATAGATTGGTTT
CCTGTGGCTCCCTCCAAACCTGGCCAAGCCCAGCTTCCGAAGCAGGAACCAGCACTGTCTCTGTGCCTGACTCACAGCATATAGGTCAGG
AAAGAATGGAGACGGCATTCTTGGACTTCACTGGGGCTGCTGGATTGGATGGGAAACCTTCTGGAAGAGGCAGATGGGGGTCAAACCACT
GCCTTGGCCCCAGGAAGGGGCCATAGGTAGGTCTGAACAACTGCCGCAAGACCACTACATGACTTAGGGAACTTGAAACCAACTGGCTCA
TGGAGAAAACAAATTTGACTTGGGAAAGGGATTATGTAGGAATAATGTTTGGACTTGATTTCCCCACGTCATAATGAAGAATGGAAGTTT
GGATCTGCTCCTCGTCAGGCGCAGCATCTCTGAAGCTTGGAAAGCTGTCTTCCAGCAGCCTCCGTGGCCTCGGGTTCCTACCGGCTTCTC
TGCATTTGGTCTGCTGATCATGTTGCCATAATGTGTATGGAAAGTGTAACACATTCTTACTGGTTAAAGACGACTACCAGGTATCTAACT
TGTTTAACATTGAGTTTGTGTGTGTGTGTGTATGTTTGTGTGTTTTGTATATTGTTTACATTTTGAGAGGTAGCATTCTGTTTCAAATGC
TTTTTGTTTTTCTGACAGTATTGTTGACTGGGTCATAACATTTTGAGCTGTGGTTTGGTGGATTTTCAATTTTTTTTTTTAAAGGTCATT
CGCTGTGCTATCTTCAAAACCTTGAGTTTGGCCCCCAATTTTTGGCATTCAAATGTTTAAAAGCTATTTATCTTGGTTTATACAAGTTTC
CTTTCTCTTCTTTTTGTCATGGTATTCTATTTGGTCTGCAGTTTGAATGTAGAGAAAGTGGACTGATCCCCCAAGCGTTGTCTGCCCCCA
CTCTTTCCTCCTTGGGTCCCGCCATTCTTTTACTGGGCAGTCGAGGGCATTGGAGGGGAAGTGACTGCCCTCAGCCTCACTCCCTGGGGC
CATGAAGAAAAGCTAAACAGTCTCATGGCATCTCAGAATAATGTTGGGTCTCCCAAGAAGAAAGGTGTAAGAATAACGACATGGCTGATT
AGGCGAGGCCAGGATAGGGCTAAGGCCAGGATTCCTGGCTGGCATCCAGTCACCCCTTCTCCCATCCTTCCCCCTCTTCTTCCACAAGTC
CGCAGCCGAGACACTGTAGTCTCCCAGCCACAGTGATGAGTGCCCTGGAGACTCCACTGACCTCTAGATGAAGGCCCCTGGCCCTGGTTC
CTGTTAATTAACCTCTGGGTCTTTGAGTCCCCCAGCACAAACTTCTTTCCTGTACCCTGCGGCTTGGGGTCACAGGGCATGCCGGGAAGC
CACAGCTGAGGGGCGCAGACTGAAGCAGTGCTCCACCTCTCCTTCTTTAGCTCAGGGGTTGCTGGTCTGTGGCAGGCGCCACGAGTGGCC
CCTGTGGCTGTTCTCAGTGGCAGTCTCTTAAGTTCCCACCACAGGCAGCTCTTTATCCCCTCTCCCTACTTGACTCTTTCTCTTGCCTGT
GCTTTTGGCCTCAAACAGGCCTGCTGGTAGCGCTCAGGGCGTGAGGCTACACTCCTGCCCTGCCTTTCCTGTCTTCATGGTCTGCCAGGG
CATACCTTGGGGAGGTGGACCAAAGACCCAGGACTTTTTGCAGTAGCCAGTCCTACCCCCCAGTTGTCTTTTTACCAATTCAGGGTGGGA
GAGAAAACTGCAGCACCCCAGCATGTGAGTTACTCAGGTGTTGGGGGCTAGAAGGGACAGTGCGTTTAAACAACACTCAGAGCTCTGGCC
TTAAACCTGTGGCCCCCCAAGTCTAGGAGCCTCATCTCTTCCTGGCAGTCATGCGGGCAGGAGGTCCTGAAAGGGAAAACCCATTCAGAC
AACTGTTCCCCAATCTACCAGCCATCTGCAGGGGTCAGTGACCGTGGCCCTCTCCCTCCTCTAGAATGTGCCACTTATGAAGAGTGCCCC
ATGGGGAAAAGGAGACTCAGCTGTCCCTTGGCAGCTTGTGCCAGTATCCCAGGGCAGAAGTTTCCACAGGAGCCTCTTGCCCTTGCGCAG
AGCCACTGTGAGAGGCGGTGGGAGCCAACACCCTTGGGGGAGGGGGCAGTACTGCTCGGCACATCCCAGCATCAGGTCAGATCATTGAAA
TTAAAAAATGTGAATTAAGTTCATATCCACCTTTTGGGGAAGCAGGACAAACCACCACCCCACCAAGTGTGTGACTTCTCCATATCCCAC
TGCAGTTTCCATTTTTTAAATGGGAATTTTCAATCCCCTGTGCTTGTCTAACGTCTGCTTTAAAAAGTTTGAGACCCTGTTACTGTTTGA

>29665_29665_1_FBXL20-PIP4K2B_FBXL20_chr17_37557614_ENST00000264658_PIP4K2B_chr17_36927525_ENST00000269554_length(amino acids)=161AA_BP=0
MRRDVNGVTKSRFEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPS

--------------------------------------------------------------
>29665_29665_2_FBXL20-PIP4K2B_FBXL20_chr17_37557614_ENST00000394294_PIP4K2B_chr17_36927525_ENST00000269554_length(transcript)=4709nt_BP=263nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTC
CCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCC
GCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGTTCTTGG
CACAGCTGAAGATCATGGACTACAGCCTGCTGGTGGGCATCCACGACGTGGACCGGGCAGAGCAGGAGGAGATGGAGGTGGAGGAGCGGG
CAGAGGACGAGGAGTGTGAGAATGATGGGGTGGGTGGCAACCTACTCTGCTCCTATGGCACACCTCCGGACAGCCCTGGCAACCTCCTCA
GCTTTCCTCGGTTCTTTGGTCCTGGGGAATTCGACCCCTCTGTTGACGTCTATGCCATGAAAAGCCATGAAAGTTCCCCCAAGAAGGAGG
TGTATTTCATGGCCATCATTGATATCCTCACGCCATACGATACAAAGAAGAAAGCTGCACATGCTGCCAAAACGGTGAAACACGGGGCAG
GGGCCGAGATCTCGACTGTGAACCCTGAGCAGTACTCCAAACGCTTCAACGAGTTTATGTCCAACATCCTGACGTAGTTCTCTTCTACCT
TCAGCCAGAGCCAGAGAGCTGGATATGGGGTCGGGGATCGGGAGTTAGGGAGAAGGGTGTATTTGGGCTAGATGGGAGGGTGGGAGCAGA
GTCGGGTTTGGGAGGGCTTTAGCAATGAGACTGCAGCCTGTGACACCGAAAGAGACTTTAGCTGAAGAGGAGGGGGATGTGCTGTGTGTG
CACCTGCTCACAGGATGTAACCCCACCTTCTGCTTACCCTTGATTTTTTCTCCCCATTTGACACCCAGGTTAAAAAGGGGTTCCCTTTTT
GGTACCTTGTAACCTTTTAAGATACCTTGGGGCTAGAGATGACTTCGTGGGTTTATTTGGGTTTTGTTTCTGAAATTTCATTGCTCCAGG
TTTGCTATTTATAATCATATTTCATCAGCCTACCCACCCTCCCCATCTTTGCTGAGCTCTCAGTTCCCTTCAATTAAAGAGATACCCGGT
AGACCCAGCACAAGGGTCCTTCCAGAACCAAGTGCTATGGATGCCAGATTGGAGAGGTCAGACACCTCGCCCTGCTGCATTTGCTCTTGT
CTGGATTAACTTTGTAATTTATGGAGTATTGTGCACAACTTCCTCCACCTTTCCCTTGGATTCAAGTGAAAACTGTTGCATTATTCCTCC
ATCCTGTCTGGAATACACCAGGTCAACACCAGAGATCTCAGATCAGAATCAGAGATCTCAGAGGGGAATAAGTTCATCCTCATGGGATGG
TGAGGGGCAGGAAAGCGGCTGGGCTCTTGGACACCTGGTTCTCAGAGAACCCTGTGATGATCACCCAAGCCCCAGGCTGTCTTAGCCCCT
GGAGTTCAGAAGTCCTCTCTGTAAAGCCTGCCTCCCACTAGGTCAAGAGGAACTAGAGTACCTTTGGATTTATCAGGACCCTCATGTTTA
AATGGTTATTTCCCTTTGGGAAAACTTCAGAAACTGATGTATCAAATGAGGCCCTGTGCCCTCGATCTATTTCCTTCTTCCTTCTGACCT
CCTCCCAGGCACTCTTACTTCTAGCCGAACTCTTAGCTCTGGGCAGATCTCCAAGCGCCTGGAGTGCTTTTTAGCAGAGACACCTCGTTA
AGCTCCGGGATGACCTTGTAGGAGATCTGTCTCCCTGTGCCTGGAGAGTTACAGCCAGCAAGGTGCCCCCATCTTAGAGTGTGGTGTCCA
AACGTGAGGTGGCTTCCTAGTTACATGAGGATGTGATCCAGGAAATCCAGTTTGGAGGCTTGATGTGGGTTTTGACCTGGCCTCAGCCTT
GGGGCTGTTTTTCCTTGTTGCCCCGCTCTAGACTTTTAGCAGATCTGCAGCCCACAGGCTTTTTTGGAAGGAGTGGCTTCCTGCAGGTGT
TCCACCTGCCTTCGGAGCCTGCCACCCAGGCCCTCAGAACTGAGCCACAGGCTGCTCTGGCCAGGAGAGAAACAGCTCTGTTGTTCTGCA
TTGGGGGAGGTACATTCCTGCATCTTCTCACCCCCTCAACCAGGAACTGGGGATTTGGGATGAGATATGGTCAGACTTGTAGATAACCCC
AAAGATGTGAAGATCGCTTGTGAAACCATTTTGAATGAATAGATTGGTTTCCTGTGGCTCCCTCCAAACCTGGCCAAGCCCAGCTTCCGA
AGCAGGAACCAGCACTGTCTCTGTGCCTGACTCACAGCATATAGGTCAGGAAAGAATGGAGACGGCATTCTTGGACTTCACTGGGGCTGC
TGGATTGGATGGGAAACCTTCTGGAAGAGGCAGATGGGGGTCAAACCACTGCCTTGGCCCCAGGAAGGGGCCATAGGTAGGTCTGAACAA
CTGCCGCAAGACCACTACATGACTTAGGGAACTTGAAACCAACTGGCTCATGGAGAAAACAAATTTGACTTGGGAAAGGGATTATGTAGG
AATAATGTTTGGACTTGATTTCCCCACGTCATAATGAAGAATGGAAGTTTGGATCTGCTCCTCGTCAGGCGCAGCATCTCTGAAGCTTGG
AAAGCTGTCTTCCAGCAGCCTCCGTGGCCTCGGGTTCCTACCGGCTTCTCTGCATTTGGTCTGCTGATCATGTTGCCATAATGTGTATGG
AAAGTGTAACACATTCTTACTGGTTAAAGACGACTACCAGGTATCTAACTTGTTTAACATTGAGTTTGTGTGTGTGTGTGTATGTTTGTG
TGTTTTGTATATTGTTTACATTTTGAGAGGTAGCATTCTGTTTCAAATGCTTTTTGTTTTTCTGACAGTATTGTTGACTGGGTCATAACA
TTTTGAGCTGTGGTTTGGTGGATTTTCAATTTTTTTTTTTAAAGGTCATTCGCTGTGCTATCTTCAAAACCTTGAGTTTGGCCCCCAATT
TTTGGCATTCAAATGTTTAAAAGCTATTTATCTTGGTTTATACAAGTTTCCTTTCTCTTCTTTTTGTCATGGTATTCTATTTGGTCTGCA
GTTTGAATGTAGAGAAAGTGGACTGATCCCCCAAGCGTTGTCTGCCCCCACTCTTTCCTCCTTGGGTCCCGCCATTCTTTTACTGGGCAG
TCGAGGGCATTGGAGGGGAAGTGACTGCCCTCAGCCTCACTCCCTGGGGCCATGAAGAAAAGCTAAACAGTCTCATGGCATCTCAGAATA
ATGTTGGGTCTCCCAAGAAGAAAGGTGTAAGAATAACGACATGGCTGATTAGGCGAGGCCAGGATAGGGCTAAGGCCAGGATTCCTGGCT
GGCATCCAGTCACCCCTTCTCCCATCCTTCCCCCTCTTCTTCCACAAGTCCGCAGCCGAGACACTGTAGTCTCCCAGCCACAGTGATGAG
TGCCCTGGAGACTCCACTGACCTCTAGATGAAGGCCCCTGGCCCTGGTTCCTGTTAATTAACCTCTGGGTCTTTGAGTCCCCCAGCACAA
ACTTCTTTCCTGTACCCTGCGGCTTGGGGTCACAGGGCATGCCGGGAAGCCACAGCTGAGGGGCGCAGACTGAAGCAGTGCTCCACCTCT
CCTTCTTTAGCTCAGGGGTTGCTGGTCTGTGGCAGGCGCCACGAGTGGCCCCTGTGGCTGTTCTCAGTGGCAGTCTCTTAAGTTCCCACC
ACAGGCAGCTCTTTATCCCCTCTCCCTACTTGACTCTTTCTCTTGCCTGTGCTTTTGGCCTCAAACAGGCCTGCTGGTAGCGCTCAGGGC
GTGAGGCTACACTCCTGCCCTGCCTTTCCTGTCTTCATGGTCTGCCAGGGCATACCTTGGGGAGGTGGACCAAAGACCCAGGACTTTTTG
CAGTAGCCAGTCCTACCCCCCAGTTGTCTTTTTACCAATTCAGGGTGGGAGAGAAAACTGCAGCACCCCAGCATGTGAGTTACTCAGGTG
TTGGGGGCTAGAAGGGACAGTGCGTTTAAACAACACTCAGAGCTCTGGCCTTAAACCTGTGGCCCCCCAAGTCTAGGAGCCTCATCTCTT
CCTGGCAGTCATGCGGGCAGGAGGTCCTGAAAGGGAAAACCCATTCAGACAACTGTTCCCCAATCTACCAGCCATCTGCAGGGGTCAGTG
ACCGTGGCCCTCTCCCTCCTCTAGAATGTGCCACTTATGAAGAGTGCCCCATGGGGAAAAGGAGACTCAGCTGTCCCTTGGCAGCTTGTG
CCAGTATCCCAGGGCAGAAGTTTCCACAGGAGCCTCTTGCCCTTGCGCAGAGCCACTGTGAGAGGCGGTGGGAGCCAACACCCTTGGGGG
AGGGGGCAGTACTGCTCGGCACATCCCAGCATCAGGTCAGATCATTGAAATTAAAAAATGTGAATTAAGTTCATATCCACCTTTTGGGGA
AGCAGGACAAACCACCACCCCACCAAGTGTGTGACTTCTCCATATCCCACTGCAGTTTCCATTTTTTAAATGGGAATTTTCAATCCCCTG
TGCTTGTCTAACGTCTGCTTTAAAAAGTTTGAGACCCTGTTACTGTTTGAAAATGCATGCATGTTACGATGAATCTCCAACCTGAGGAAA

>29665_29665_2_FBXL20-PIP4K2B_FBXL20_chr17_37557614_ENST00000394294_PIP4K2B_chr17_36927525_ENST00000269554_length(amino acids)=161AA_BP=0
MRRDVNGVTKSRFEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPS

--------------------------------------------------------------
>29665_29665_3_FBXL20-PIP4K2B_FBXL20_chr17_37557614_ENST00000583610_PIP4K2B_chr17_36927525_ENST00000269554_length(transcript)=4742nt_BP=296nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTG
GAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCC
GGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGA
ACGGAGTGACCAAGAGCAGGTTTGAGTTCTTGGCACAGCTGAAGATCATGGACTACAGCCTGCTGGTGGGCATCCACGACGTGGACCGGG
CAGAGCAGGAGGAGATGGAGGTGGAGGAGCGGGCAGAGGACGAGGAGTGTGAGAATGATGGGGTGGGTGGCAACCTACTCTGCTCCTATG
GCACACCTCCGGACAGCCCTGGCAACCTCCTCAGCTTTCCTCGGTTCTTTGGTCCTGGGGAATTCGACCCCTCTGTTGACGTCTATGCCA
TGAAAAGCCATGAAAGTTCCCCCAAGAAGGAGGTGTATTTCATGGCCATCATTGATATCCTCACGCCATACGATACAAAGAAGAAAGCTG
CACATGCTGCCAAAACGGTGAAACACGGGGCAGGGGCCGAGATCTCGACTGTGAACCCTGAGCAGTACTCCAAACGCTTCAACGAGTTTA
TGTCCAACATCCTGACGTAGTTCTCTTCTACCTTCAGCCAGAGCCAGAGAGCTGGATATGGGGTCGGGGATCGGGAGTTAGGGAGAAGGG
TGTATTTGGGCTAGATGGGAGGGTGGGAGCAGAGTCGGGTTTGGGAGGGCTTTAGCAATGAGACTGCAGCCTGTGACACCGAAAGAGACT
TTAGCTGAAGAGGAGGGGGATGTGCTGTGTGTGCACCTGCTCACAGGATGTAACCCCACCTTCTGCTTACCCTTGATTTTTTCTCCCCAT
TTGACACCCAGGTTAAAAAGGGGTTCCCTTTTTGGTACCTTGTAACCTTTTAAGATACCTTGGGGCTAGAGATGACTTCGTGGGTTTATT
TGGGTTTTGTTTCTGAAATTTCATTGCTCCAGGTTTGCTATTTATAATCATATTTCATCAGCCTACCCACCCTCCCCATCTTTGCTGAGC
TCTCAGTTCCCTTCAATTAAAGAGATACCCGGTAGACCCAGCACAAGGGTCCTTCCAGAACCAAGTGCTATGGATGCCAGATTGGAGAGG
TCAGACACCTCGCCCTGCTGCATTTGCTCTTGTCTGGATTAACTTTGTAATTTATGGAGTATTGTGCACAACTTCCTCCACCTTTCCCTT
GGATTCAAGTGAAAACTGTTGCATTATTCCTCCATCCTGTCTGGAATACACCAGGTCAACACCAGAGATCTCAGATCAGAATCAGAGATC
TCAGAGGGGAATAAGTTCATCCTCATGGGATGGTGAGGGGCAGGAAAGCGGCTGGGCTCTTGGACACCTGGTTCTCAGAGAACCCTGTGA
TGATCACCCAAGCCCCAGGCTGTCTTAGCCCCTGGAGTTCAGAAGTCCTCTCTGTAAAGCCTGCCTCCCACTAGGTCAAGAGGAACTAGA
GTACCTTTGGATTTATCAGGACCCTCATGTTTAAATGGTTATTTCCCTTTGGGAAAACTTCAGAAACTGATGTATCAAATGAGGCCCTGT
GCCCTCGATCTATTTCCTTCTTCCTTCTGACCTCCTCCCAGGCACTCTTACTTCTAGCCGAACTCTTAGCTCTGGGCAGATCTCCAAGCG
CCTGGAGTGCTTTTTAGCAGAGACACCTCGTTAAGCTCCGGGATGACCTTGTAGGAGATCTGTCTCCCTGTGCCTGGAGAGTTACAGCCA
GCAAGGTGCCCCCATCTTAGAGTGTGGTGTCCAAACGTGAGGTGGCTTCCTAGTTACATGAGGATGTGATCCAGGAAATCCAGTTTGGAG
GCTTGATGTGGGTTTTGACCTGGCCTCAGCCTTGGGGCTGTTTTTCCTTGTTGCCCCGCTCTAGACTTTTAGCAGATCTGCAGCCCACAG
GCTTTTTTGGAAGGAGTGGCTTCCTGCAGGTGTTCCACCTGCCTTCGGAGCCTGCCACCCAGGCCCTCAGAACTGAGCCACAGGCTGCTC
TGGCCAGGAGAGAAACAGCTCTGTTGTTCTGCATTGGGGGAGGTACATTCCTGCATCTTCTCACCCCCTCAACCAGGAACTGGGGATTTG
GGATGAGATATGGTCAGACTTGTAGATAACCCCAAAGATGTGAAGATCGCTTGTGAAACCATTTTGAATGAATAGATTGGTTTCCTGTGG
CTCCCTCCAAACCTGGCCAAGCCCAGCTTCCGAAGCAGGAACCAGCACTGTCTCTGTGCCTGACTCACAGCATATAGGTCAGGAAAGAAT
GGAGACGGCATTCTTGGACTTCACTGGGGCTGCTGGATTGGATGGGAAACCTTCTGGAAGAGGCAGATGGGGGTCAAACCACTGCCTTGG
CCCCAGGAAGGGGCCATAGGTAGGTCTGAACAACTGCCGCAAGACCACTACATGACTTAGGGAACTTGAAACCAACTGGCTCATGGAGAA
AACAAATTTGACTTGGGAAAGGGATTATGTAGGAATAATGTTTGGACTTGATTTCCCCACGTCATAATGAAGAATGGAAGTTTGGATCTG
CTCCTCGTCAGGCGCAGCATCTCTGAAGCTTGGAAAGCTGTCTTCCAGCAGCCTCCGTGGCCTCGGGTTCCTACCGGCTTCTCTGCATTT
GGTCTGCTGATCATGTTGCCATAATGTGTATGGAAAGTGTAACACATTCTTACTGGTTAAAGACGACTACCAGGTATCTAACTTGTTTAA
CATTGAGTTTGTGTGTGTGTGTGTATGTTTGTGTGTTTTGTATATTGTTTACATTTTGAGAGGTAGCATTCTGTTTCAAATGCTTTTTGT
TTTTCTGACAGTATTGTTGACTGGGTCATAACATTTTGAGCTGTGGTTTGGTGGATTTTCAATTTTTTTTTTTAAAGGTCATTCGCTGTG
CTATCTTCAAAACCTTGAGTTTGGCCCCCAATTTTTGGCATTCAAATGTTTAAAAGCTATTTATCTTGGTTTATACAAGTTTCCTTTCTC
TTCTTTTTGTCATGGTATTCTATTTGGTCTGCAGTTTGAATGTAGAGAAAGTGGACTGATCCCCCAAGCGTTGTCTGCCCCCACTCTTTC
CTCCTTGGGTCCCGCCATTCTTTTACTGGGCAGTCGAGGGCATTGGAGGGGAAGTGACTGCCCTCAGCCTCACTCCCTGGGGCCATGAAG
AAAAGCTAAACAGTCTCATGGCATCTCAGAATAATGTTGGGTCTCCCAAGAAGAAAGGTGTAAGAATAACGACATGGCTGATTAGGCGAG
GCCAGGATAGGGCTAAGGCCAGGATTCCTGGCTGGCATCCAGTCACCCCTTCTCCCATCCTTCCCCCTCTTCTTCCACAAGTCCGCAGCC
GAGACACTGTAGTCTCCCAGCCACAGTGATGAGTGCCCTGGAGACTCCACTGACCTCTAGATGAAGGCCCCTGGCCCTGGTTCCTGTTAA
TTAACCTCTGGGTCTTTGAGTCCCCCAGCACAAACTTCTTTCCTGTACCCTGCGGCTTGGGGTCACAGGGCATGCCGGGAAGCCACAGCT
GAGGGGCGCAGACTGAAGCAGTGCTCCACCTCTCCTTCTTTAGCTCAGGGGTTGCTGGTCTGTGGCAGGCGCCACGAGTGGCCCCTGTGG
CTGTTCTCAGTGGCAGTCTCTTAAGTTCCCACCACAGGCAGCTCTTTATCCCCTCTCCCTACTTGACTCTTTCTCTTGCCTGTGCTTTTG
GCCTCAAACAGGCCTGCTGGTAGCGCTCAGGGCGTGAGGCTACACTCCTGCCCTGCCTTTCCTGTCTTCATGGTCTGCCAGGGCATACCT
TGGGGAGGTGGACCAAAGACCCAGGACTTTTTGCAGTAGCCAGTCCTACCCCCCAGTTGTCTTTTTACCAATTCAGGGTGGGAGAGAAAA
CTGCAGCACCCCAGCATGTGAGTTACTCAGGTGTTGGGGGCTAGAAGGGACAGTGCGTTTAAACAACACTCAGAGCTCTGGCCTTAAACC
TGTGGCCCCCCAAGTCTAGGAGCCTCATCTCTTCCTGGCAGTCATGCGGGCAGGAGGTCCTGAAAGGGAAAACCCATTCAGACAACTGTT
CCCCAATCTACCAGCCATCTGCAGGGGTCAGTGACCGTGGCCCTCTCCCTCCTCTAGAATGTGCCACTTATGAAGAGTGCCCCATGGGGA
AAAGGAGACTCAGCTGTCCCTTGGCAGCTTGTGCCAGTATCCCAGGGCAGAAGTTTCCACAGGAGCCTCTTGCCCTTGCGCAGAGCCACT
GTGAGAGGCGGTGGGAGCCAACACCCTTGGGGGAGGGGGCAGTACTGCTCGGCACATCCCAGCATCAGGTCAGATCATTGAAATTAAAAA
ATGTGAATTAAGTTCATATCCACCTTTTGGGGAAGCAGGACAAACCACCACCCCACCAAGTGTGTGACTTCTCCATATCCCACTGCAGTT
TCCATTTTTTAAATGGGAATTTTCAATCCCCTGTGCTTGTCTAACGTCTGCTTTAAAAAGTTTGAGACCCTGTTACTGTTTGAAAATGCA

>29665_29665_3_FBXL20-PIP4K2B_FBXL20_chr17_37557614_ENST00000583610_PIP4K2B_chr17_36927525_ENST00000269554_length(amino acids)=161AA_BP=0
MRRDVNGVTKSRFEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FBXL20-PIP4K2B

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for FBXL20-PIP4K2B

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for FBXL20-PIP4K2B

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source