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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FBXO18-FRMD4A (FusionGDB2 ID:29764)

Fusion Gene Summary for FBXO18-FRMD4A

check button Fusion gene summary
Fusion gene informationFusion gene name: FBXO18-FRMD4A
Fusion gene ID: 29764
HgeneTgene
Gene symbol

FBXO18

FRMD4A

Gene ID

84893

55691

Gene nameF-box DNA helicase 1FERM domain containing 4A
SynonymsFBXO18|Fbx18|hFBH1CCAFCA|FRMD4|bA295P9.4
Cytomap

10p15.1

10p13

Type of geneprotein-codingprotein-coding
DescriptionF-box DNA helicase 1F-box only protein, helicase, 18F-box protein, helicase, 18FERM domain-containing protein 4AFERM domain containing 4
Modification date2020031320200313
UniProtAcc.

Q9P2Q2

Ensembl transtripts involved in fusion geneENST00000470089, ENST00000362091, 
ENST00000379999, ENST00000397269, 
ENST00000357447, ENST00000358621, 
ENST00000378503, ENST00000342409, 
ENST00000475141, ENST00000492155, 
ENST00000493380, 
Fusion gene scores* DoF score3 X 3 X 3=2715 X 13 X 6=1170
# samples 318
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(18/1170*10)=-2.70043971814109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FBXO18 [Title/Abstract] AND FRMD4A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFBXO18(5932309)-FRMD4A(13717044), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFBXO18

GO:0006974

cellular response to DNA damage stimulus

19736316|23319600|23361013|25585578

HgeneFBXO18

GO:0008219

cell death

23319600

HgeneFBXO18

GO:0016567

protein ubiquitination

25585578

HgeneFBXO18

GO:0031297

replication fork processing

25585578

HgeneFBXO18

GO:2000042

negative regulation of double-strand break repair via homologous recombination

19736316


check buttonFusion gene breakpoints across FBXO18 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FRMD4A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-J4-A83M-01AFBXO18chr10

5932309

-FRMD4Achr10

13717044

-
ChimerDB4PRADTCGA-J4-A83M-01AFBXO18chr10

5932309

+FRMD4Achr10

13717044

-


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Fusion Gene ORF analysis for FBXO18-FRMD4A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000470089ENST00000357447FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
3UTR-3CDSENST00000470089ENST00000358621FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
3UTR-3CDSENST00000470089ENST00000378503FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
3UTR-intronENST00000470089ENST00000342409FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
3UTR-intronENST00000470089ENST00000475141FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
3UTR-intronENST00000470089ENST00000492155FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
3UTR-intronENST00000470089ENST00000493380FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
5CDS-intronENST00000362091ENST00000342409FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
5CDS-intronENST00000362091ENST00000475141FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
5CDS-intronENST00000362091ENST00000492155FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
5CDS-intronENST00000362091ENST00000493380FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
In-frameENST00000362091ENST00000357447FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
In-frameENST00000362091ENST00000358621FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
In-frameENST00000362091ENST00000378503FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-3CDSENST00000379999ENST00000357447FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-3CDSENST00000379999ENST00000358621FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-3CDSENST00000379999ENST00000378503FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-3CDSENST00000397269ENST00000357447FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-3CDSENST00000397269ENST00000358621FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-3CDSENST00000397269ENST00000378503FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000379999ENST00000342409FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000379999ENST00000475141FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000379999ENST00000492155FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000379999ENST00000493380FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000397269ENST00000342409FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000397269ENST00000475141FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000397269ENST00000492155FBXO18chr10

5932309

+FRMD4Achr10

13717044

-
intron-intronENST00000397269ENST00000493380FBXO18chr10

5932309

+FRMD4Achr10

13717044

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000362091FBXO18chr105932309+ENST00000358621FRMD4Achr1013717044-54511161572118653
ENST00000362091FBXO18chr105932309+ENST00000357447FRMD4Achr1013717044-54451161572118653
ENST00000362091FBXO18chr105932309+ENST00000378503FRMD4Achr1013717044-21191161572118654

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000362091ENST00000358621FBXO18chr105932309+FRMD4Achr1013717044-0.0081217860.9918783
ENST00000362091ENST00000357447FBXO18chr105932309+FRMD4Achr1013717044-0.0081459860.99185395
ENST00000362091ENST00000378503FBXO18chr105932309+FRMD4Achr1013717044-0.026469240.97353077

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Fusion Genomic Features for FBXO18-FRMD4A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FBXO18-FRMD4A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:5932309/chr10:13717044)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FRMD4A

Q9P2Q2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling (PubMed:27044754). {ECO:0000250|UniProtKB:Q8BIE6, ECO:0000269|PubMed:27044754}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFRMD4Achr10:5932309chr10:13717044ENST000003574471425382_4163722034.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Achr10:5932309chr10:13717044ENST000003785031323382_4163721040.0Coiled coilOntology_term=ECO:0000255
TgeneFRMD4Achr10:5932309chr10:13717044ENST000003574471425627_7563722034.0Compositional biasNote=Ser-rich
TgeneFRMD4Achr10:5932309chr10:13717044ENST000003574471425935_10073722034.0Compositional biasNote=Ser-rich
TgeneFRMD4Achr10:5932309chr10:13717044ENST000003785031323627_7563721040.0Compositional biasNote=Ser-rich
TgeneFRMD4Achr10:5932309chr10:13717044ENST000003785031323935_10073721040.0Compositional biasNote=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFBXO18chr10:5932309chr10:13717044ENST00000362091+121138_18401044.0DomainF-box
HgeneFBXO18chr10:5932309chr10:13717044ENST00000362091+121442_70501044.0DomainUvrD-like helicase ATP-binding
HgeneFBXO18chr10:5932309chr10:13717044ENST00000379999+122138_18401095.0DomainF-box
HgeneFBXO18chr10:5932309chr10:13717044ENST00000379999+122442_70501095.0DomainUvrD-like helicase ATP-binding
HgeneFBXO18chr10:5932309chr10:13717044ENST00000362091+12157_6401044.0MotifPIP-box
HgeneFBXO18chr10:5932309chr10:13717044ENST00000362091+121807_81101044.0MotifAPIM motif
HgeneFBXO18chr10:5932309chr10:13717044ENST00000379999+12257_6401095.0MotifPIP-box
HgeneFBXO18chr10:5932309chr10:13717044ENST00000379999+122807_81101095.0MotifAPIM motif
HgeneFBXO18chr10:5932309chr10:13717044ENST00000362091+121463_47001044.0Nucleotide bindingATP
HgeneFBXO18chr10:5932309chr10:13717044ENST00000379999+122463_47001095.0Nucleotide bindingATP
TgeneFRMD4Achr10:5932309chr10:13717044ENST00000357447142520_3223722034.0DomainFERM
TgeneFRMD4Achr10:5932309chr10:13717044ENST00000378503132320_3223721040.0DomainFERM


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Fusion Gene Sequence for FBXO18-FRMD4A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>29764_29764_1_FBXO18-FRMD4A_FBXO18_chr10_5932309_ENST00000362091_FRMD4A_chr10_13717044_ENST00000357447_length(transcript)=5445nt_BP=116nt
CTCGGGCTCCAGGTCCCGGCCAGAGGAGGAGCTCGCTGCCGGGGGACGCTGGGCTGAGCGGCCGGCGGCGCGGGCCCGGCGGCGGCGGCA
GCGGGGTCCGGGTCCGGAGCGCCACAGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAG
GCAGGAAGCTCTGGAGGAAACCCTGCGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCC
AGTAGAATATCCCCTGGATCCAGGGGAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCT
GCCCAAAGGAGAGGAAGCTGAGCTGGAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAG
TGACCCCAACGTCAGCAAAAAACTGAAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAAT
CAATGAGAACCGCATCAAGTCTGGGAAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTC
CCTCTCAGATGCCCTTGTTCTTGAGGATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCC
TCGGCCACCGTCGCACAACAGGCCTCCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTC
ACCCATCAAGCCCAAAATGTGGAGTGAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAG
CCACAAGCGCTTCCCCAGCACAGGAAGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCA
CTGGAACTCCCAGTCCAGCATGCCGTCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAG
CCCCACCCGACTGCACAGCCTCGCACTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGA
CACCGGGAGCCCCGACTTCTACACCCCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTC
GAGCTCGGAGCACTACTACCCGGCGCAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAG
GCAGCGGCAGCGGGCGGCGGGCGCACTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGG
GGGCGCGGGGGGCGGTGTGTACCTGCACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGG
CGCCACGCCCGTGGTGGTGCGCAGCCTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACAC
GGCGGGCGGCCTGTTCAAGGAGAGCTGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCT
GCGGACTCCGTCGCTGGGCCGCGAGGGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCG
TTCCACCGCCTCGCACAAGGAGCACAGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCA
GAGCACCTTCGTGGCGCACAGCAGGGTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTC
GACACCGTCAAGTGAAATTGGAGCCACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACC
CATTCTGGATGGGTCTGAGTCTCCACCTCACCAAAGTACTGATGAATAGAGGAGCTACAATGATAGCTGTTTCCTGGATTCCTCCCTCTA
TCCAGAACTAGCTGATGTCCAGTGGTACGGGCAGGAAAAAGCCAAGCCCGGGACCCTCGTGTGAGCCAGCCCGGCCTAATCTGACCGCCT
CAACGCCATTCTGAGATCACCTCACTGCCTCTCATTTGCCTTACCCAGACGCACCGTCACCCTGCACCAGCTTTGGCCCTCAGCACTTTT
TTTCTCCTGTCTCCGCATTCCCTCCCCCTTGAAAACCTGACTGAGGAGACATTCTGGAAGGTTCCGGTCCCACTGTGTGTCCCCTGGCGC
TCTTGCCCATAGAGAGCCAGACACCAATCCTCAATGGCACCTTGGTGGCTTCCCTCTGCCATGACAGCCCCTAGGCCAGGAACCATCAGG
GGGGCCAGCCGGCATCCAATTCCTGCGGATAAGTAGCGTTGGGAGAGAACGGGAAAGGGGACTTGAGTTACAGGGTGACCCAGAAAGACG
ATTCAGCTGTGTCCAGCCTGCCACCCATACGTAGGCCAACCAAGCACTTCATGAAGAGGAGGCCTCGTGGCATATTCAGTTTACACCTGA
AATATTCCTTGATGGGACAGCTTGTGGGGATGGCTATGGGGGAAGGGGAGGTTGAGAAAGGAAGTTCTCGACACCAGAAATGCATCGGAG
GACCACAATCAGTTCTATGCTGCCAAAGATTAAAAATAAATAAAAACATAAAAAATTAAGAGGGGCCAAGAGGAAGACATTCTTTCTGCA
AGGAAATTTCTTTTAAATTCTGAACTGCTACTACACACAAGTGAAAGTCAACCCTATGTAAACTGGTGTCCTCTCTCTAGCCCTCTCCCT
TACTGGCCCACTTCTCTCTCCGTAGAGAGCCTGAAAAACTGCCCCAATGCCACGGTAAAGGCGAGGAAGTCTTGGCTGGCGTTGCTGACT
CACAGTCGCCATCCATCTGGACACAAAGAGAGACCTGTGGGAGTCGTAGAGGGTACTGTTAGCCCCGGTCCATGCAGGGGGTTCAGCCGA
GCCCAAGACTCAAAGCTGCTTTCCTTTCAGGATTTGTAGTAACGTAAGGTGATAATGGCCAAAAGTGGTTCTCTCTCATTAAACCAACCA
GTAAAAGCGTATCCTATTTTTTTGCACAAGGTGTTTCATTTTCGTTTTTATGGGAAACCAAGGGAAAAGCACATTGCGATCCATTCAGTG
TTTAACTGTCGTGGCTCATTTTCTGTTCGTTAGCACTTGTGTGACAAAAGAGCTCAGATCCGACTTCTCCTATGTGTCACTTATTCCAAG
AACCCAACTATGCCCTTAGGTAGAAAGATTTGACTCGTGTGTCTACTAGCCAACAGGCAGAGCAGGGTTGAAAAAAATATCAGCTCCCAA
AGGGCCCATGTGTCTACATCATCAGTTACTGTCATGCACCACATTTGTGTGCAGATACCAAAAGAGGAGGAAAGAAGAAAAAAATTAATG
TGTGGGAGCTGCACGTTTACATGTTTTGAGCTATGCTTCAAACACAACTGGAAAGCCATCAATCTTCAAAGGCCTCAAAAATACTTTTAT
AGTAACAAGTGCACGACTTTAGTTGGGTTATTCAAGATGGCACAAAAAGGTTTCCGCAGAGGTGGTATGCTGTGCTTTTGGCGCAAGTGG
TGGGGGGATGGGGTGGGGGTGGAATTTTTTTCTCACTCTAATGACTTCCTATTGGAAAGGCATTGACAGCCAGGGACAGGAGCCAGGGTG
GGGGTAGTTTTGTGGGAAAGCAGAACTGAAGTTAGCTTAAGCATAAAAACAAAGAAAAATCTTCGCTTTTCATGTATGTGGAATCCAAGA
ATAACCATAGGCTCTACCAGACCAGAAGGGTAAGGATGGACACTAAAATGAAACAAATACCAAGGTATTCCTTCTGCTGCAGCCTGGAGA
CCACCGAGAGTCGAGCTGGGGCACACACACACCTGGCCGGGACCCGGCAGGGACAAGGCGGGCCGTGGCCTCCTCCACCAAGTCTCTCTA
GACAATTCAGGGCCTGCTTTCCCCAGCTCCATGCATGGCTGGACTGGTGATTCCAGGGTGCAGAAGGGATTCATATTCCCAGAACGCTTT
AAGTGTACACCTGCAGGATAAAGAGATACCGGTTACATTATTAAATGATTCTAGGGATTCACTGGGGGATATTTTTGTTGCTTTTACTTT
CATGGTTAGAGCTACAAAGAACAGTGATTTTTTTTTTTTCTCCCTTCCCCATTCAGAAACATTATACATTGGGCCATTTTTCTTTCTCCC
AAAGAAGATTCATGGATAGTCAGACTGAACTGTGTGCAACAGGAAAAGTCAAAAGGGAAAAGGTAGCTGATGAGGTTACATGGTTACATG
TTCTACATCATGCATAGTAGCTTGAAATCTAGTCTGGAGAAAACTGGATCAAGATTCTAGCCCACTGGAGTTGCAAGGAATGAGAGGCAA
AAATTCTAAAGATTTGGGTTATATTTTCAACTTGGGGGACAGAGAGAAATGGAGAGCAGGAATTACAGTTCCAACAAACATCATGATAGT
CTGGTAGTCAAGACAGAGATTAAGTAAAACAGGTTTTACTGTTTAGCTGAGTTCAGTTAATACAAAATGTACATAAAACGTTAGTCCTTT
GAGACTGACATGATTAATGATCAGTGTGGTGGGAAATGATGTAGTTATTGTACACAAGCACTTGCAAACTCTTTATCCCTATTTCTTTAA
AACAAAATAAGGTGAAATACGAAGTCCTTGGTCTGATATAAAGCCCCTATTGGATTCTTCGGATGCGTAAAAGAAATTGCCTGTTTCAGC
CAGAAGACTGGTGAAAACACATACATCAGACTATGTTGTGAGCCAGGTTGATTTTTTATTTTATTATATGCAGGTGAGTGTTGAAACTGT
TAAAATTCCAATTTGTTTTCATTCAGTATTAGTTTAGTTCTAAATATAGCAAACCCCATCCAGGTGCTATCAGATGACCAGTTACTGCTT
AGTTAACTAGGTGTAAAGTTTTACATATACATTAATGTCAATAGTTTATTACAAGTTGTGTAAAATGGACTCTAGTTTAATAATGGGGGA
AAAAAGATTAGGTTGCTCCTGAAACTGACTGTAGAGCATGTAAAATGATTTTACTGGATTCTGTTCAACTGTAATCAATGAAAAAGATGT
ACGTTGTAGACAAAGTTGCAGAATTAAAAAAAGAAATCTGCTTTTAATTTATTCTTTTTGTATTAAGAATTTGTATAGTACCTTTACATT

>29764_29764_1_FBXO18-FRMD4A_FBXO18_chr10_5932309_ENST00000362091_FRMD4A_chr10_13717044_ENST00000357447_length(amino acids)=653AA_BP=
MLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQIT
EAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLH
SPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQN
SPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDD
CSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYLHSQSQPSSQYRIKE
YPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGREGAHDKGAGRAAVSD
ELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQT

--------------------------------------------------------------
>29764_29764_2_FBXO18-FRMD4A_FBXO18_chr10_5932309_ENST00000362091_FRMD4A_chr10_13717044_ENST00000358621_length(transcript)=5451nt_BP=116nt
CTCGGGCTCCAGGTCCCGGCCAGAGGAGGAGCTCGCTGCCGGGGGACGCTGGGCTGAGCGGCCGGCGGCGCGGGCCCGGCGGCGGCGGCA
GCGGGGTCCGGGTCCGGAGCGCCACAGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAG
GCAGGAAGCTCTGGAGGAAACCCTGCGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCC
AGTAGAATATCCCCTGGATCCAGGGGAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCT
GCCCAAAGGAGAGGAAGCTGAGCTGGAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAG
TGACCCCAACGTCAGCAAAAAACTGAAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAAT
CAATGAGAACCGCATCAAGTCTGGGAAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTC
CCTCTCAGATGCCCTTGTTCTTGAGGATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCC
TCGGCCACCGTCGCACAACAGGCCTCCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTC
ACCCATCAAGCCCAAAATGTGGAGTGAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAG
CCACAAGCGCTTCCCCAGCACAGGAAGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCA
CTGGAACTCCCAGTCCAGCATGCCGTCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAG
CCCCACCCGACTGCACAGCCTCGCACTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGA
CACCGGGAGCCCCGACTTCTACACCCCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTC
GAGCTCGGAGCACTACTACCCGGCGCAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAG
GCAGCGGCAGCGGGCGGCGGGCGCACTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGG
GGGCGCGGGGGGCGGTGTGTACCTGCACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGG
CGCCACGCCCGTGGTGGTGCGCAGCCTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACAC
GGCGGGCGGCCTGTTCAAGGAGAGCTGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCT
GCGGACTCCGTCGCTGGGCCGCGAGGGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCG
TTCCACCGCCTCGCACAAGGAGCACAGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCA
GAGCACCTTCGTGGCGCACAGCAGGGTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTC
GACACCGTCAAGTGAAATTGGAGCCACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACC
CATTCTGGATGGGTCTGAGTCTCCACCTCACCAAAGTACTGATGAATAGAGGAGCTACAATGATAGCTGTTTCCTGGATTCCTCCCTCTA
TCCAGAACTAGCTGATGTCCAGTGGTACGGGCAGGAAAAAGCCAAGCCCGGGACCCTCGTGTGAGCCAGCCCGGCCTAATCTGACCGCCT
CAACGCCATTCTGAGATCACCTCACTGCCTCTCATTTGCCTTACCCAGACGCACCGTCACCCTGCACCAGCTTTGGCCCTCAGCACTTTT
TTTCTCCTGTCTCCGCATTCCCTCCCCCTTGAAAACCTGACTGAGGAGACATTCTGGAAGGTTCCGGTCCCACTGTGTGTCCCCTGGCGC
TCTTGCCCATAGAGAGCCAGACACCAATCCTCAATGGCACCTTGGTGGCTTCCCTCTGCCATGACAGCCCCTAGGCCAGGAACCATCAGG
GGGGCCAGCCGGCATCCAATTCCTGCGGATAAGTAGCGTTGGGAGAGAACGGGAAAGGGGACTTGAGTTACAGGGTGACCCAGAAAGACG
ATTCAGCTGTGTCCAGCCTGCCACCCATACGTAGGCCAACCAAGCACTTCATGAAGAGGAGGCCTCGTGGCATATTCAGTTTACACCTGA
AATATTCCTTGATGGGACAGCTTGTGGGGATGGCTATGGGGGAAGGGGAGGTTGAGAAAGGAAGTTCTCGACACCAGAAATGCATCGGAG
GACCACAATCAGTTCTATGCTGCCAAAGATTAAAAATAAATAAAAACATAAAAAATTAAGAGGGGCCAAGAGGAAGACATTCTTTCTGCA
AGGAAATTTCTTTTAAATTCTGAACTGCTACTACACACAAGTGAAAGTCAACCCTATGTAAACTGGTGTCCTCTCTCTAGCCCTCTCCCT
TACTGGCCCACTTCTCTCTCCGTAGAGAGCCTGAAAAACTGCCCCAATGCCACGGTAAAGGCGAGGAAGTCTTGGCTGGCGTTGCTGACT
CACAGTCGCCATCCATCTGGACACAAAGAGAGACCTGTGGGAGTCGTAGAGGGTACTGTTAGCCCCGGTCCATGCAGGGGGTTCAGCCGA
GCCCAAGACTCAAAGCTGCTTTCCTTTCAGGATTTGTAGTAACGTAAGGTGATAATGGCCAAAAGTGGTTCTCTCTCATTAAACCAACCA
GTAAAAGCGTATCCTATTTTTTTGCACAAGGTGTTTCATTTTCGTTTTTATGGGAAACCAAGGGAAAAGCACATTGCGATCCATTCAGTG
TTTAACTGTCGTGGCTCATTTTCTGTTCGTTAGCACTTGTGTGACAAAAGAGCTCAGATCCGACTTCTCCTATGTGTCACTTATTCCAAG
AACCCAACTATGCCCTTAGGTAGAAAGATTTGACTCGTGTGTCTACTAGCCAACAGGCAGAGCAGGGTTGAAAAAAATATCAGCTCCCAA
AGGGCCCATGTGTCTACATCATCAGTTACTGTCATGCACCACATTTGTGTGCAGATACCAAAAGAGGAGGAAAGAAGAAAAAAATTAATG
TGTGGGAGCTGCACGTTTACATGTTTTGAGCTATGCTTCAAACACAACTGGAAAGCCATCAATCTTCAAAGGCCTCAAAAATACTTTTAT
AGTAACAAGTGCACGACTTTAGTTGGGTTATTCAAGATGGCACAAAAAGGTTTCCGCAGAGGTGGTATGCTGTGCTTTTGGCGCAAGTGG
TGGGGGGATGGGGTGGGGGTGGAATTTTTTTCTCACTCTAATGACTTCCTATTGGAAAGGCATTGACAGCCAGGGACAGGAGCCAGGGTG
GGGGTAGTTTTGTGGGAAAGCAGAACTGAAGTTAGCTTAAGCATAAAAACAAAGAAAAATCTTCGCTTTTCATGTATGTGGAATCCAAGA
ATAACCATAGGCTCTACCAGACCAGAAGGGTAAGGATGGACACTAAAATGAAACAAATACCAAGGTATTCCTTCTGCTGCAGCCTGGAGA
CCACCGAGAGTCGAGCTGGGGCACACACACACCTGGCCGGGACCCGGCAGGGACAAGGCGGGCCGTGGCCTCCTCCACCAAGTCTCTCTA
GACAATTCAGGGCCTGCTTTCCCCAGCTCCATGCATGGCTGGACTGGTGATTCCAGGGTGCAGAAGGGATTCATATTCCCAGAACGCTTT
AAGTGTACACCTGCAGGATAAAGAGATACCGGTTACATTATTAAATGATTCTAGGGATTCACTGGGGGATATTTTTGTTGCTTTTACTTT
CATGGTTAGAGCTACAAAGAACAGTGATTTTTTTTTTTTCTCCCTTCCCCATTCAGAAACATTATACATTGGGCCATTTTTCTTTCTCCC
AAAGAAGATTCATGGATAGTCAGACTGAACTGTGTGCAACAGGAAAAGTCAAAAGGGAAAAGGTAGCTGATGAGGTTACATGGTTACATG
TTCTACATCATGCATAGTAGCTTGAAATCTAGTCTGGAGAAAACTGGATCAAGATTCTAGCCCACTGGAGTTGCAAGGAATGAGAGGCAA
AAATTCTAAAGATTTGGGTTATATTTTCAACTTGGGGGACAGAGAGAAATGGAGAGCAGGAATTACAGTTCCAACAAACATCATGATAGT
CTGGTAGTCAAGACAGAGATTAAGTAAAACAGGTTTTACTGTTTAGCTGAGTTCAGTTAATACAAAATGTACATAAAACGTTAGTCCTTT
GAGACTGACATGATTAATGATCAGTGTGGTGGGAAATGATGTAGTTATTGTACACAAGCACTTGCAAACTCTTTATCCCTATTTCTTTAA
AACAAAATAAGGTGAAATACGAAGTCCTTGGTCTGATATAAAGCCCCTATTGGATTCTTCGGATGCGTAAAAGAAATTGCCTGTTTCAGC
CAGAAGACTGGTGAAAACACATACATCAGACTATGTTGTGAGCCAGGTTGATTTTTTATTTTATTATATGCAGGTGAGTGTTGAAACTGT
TAAAATTCCAATTTGTTTTCATTCAGTATTAGTTTAGTTCTAAATATAGCAAACCCCATCCAGGTGCTATCAGATGACCAGTTACTGCTT
AGTTAACTAGGTGTAAAGTTTTACATATACATTAATGTCAATAGTTTATTACAAGTTGTGTAAAATGGACTCTAGTTTAATAATGGGGGA
AAAAAGATTAGGTTGCTCCTGAAACTGACTGTAGAGCATGTAAAATGATTTTACTGGATTCTGTTCAACTGTAATCAATGAAAAAGATGT
ACGTTGTAGACAAAGTTGCAGAATTAAAAAAAGAAATCTGCTTTTAATTTATTCTTTTTGTATTAAGAATTTGTATAGTACCTTTACATT

>29764_29764_2_FBXO18-FRMD4A_FBXO18_chr10_5932309_ENST00000362091_FRMD4A_chr10_13717044_ENST00000358621_length(amino acids)=653AA_BP=
MLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQIT
EAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLH
SPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQN
SPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDD
CSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYLHSQSQPSSQYRIKE
YPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGREGAHDKGAGRAAVSD
ELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQT

--------------------------------------------------------------
>29764_29764_3_FBXO18-FRMD4A_FBXO18_chr10_5932309_ENST00000362091_FRMD4A_chr10_13717044_ENST00000378503_length(transcript)=2119nt_BP=116nt
CTCGGGCTCCAGGTCCCGGCCAGAGGAGGAGCTCGCTGCCGGGGGACGCTGGGCTGAGCGGCCGGCGGCGCGGGCCCGGCGGCGGCGGCA
GCGGGGTCCGGGTCCGGAGCGCCACAGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAG
GCAGGAAGCTCTGGAGGAAACCCTGCGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCC
AGTAGAATATCCCCTGGATCCAGGGGAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCT
GCCCAAAGGAGAGGAAGCTGAGCTGGAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAG
TGACCCCAACGTCAGCAAAAAACTGAAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAAT
CAATGAGAACCGCATCAAGTCTGGGAAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTC
CCTCTCAGATGCCCTTGTTCTTGAGGATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCC
TCGGCCACCGTCGCACAACAGGCCTCCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTC
ACCCATCAAGCCCAAAATGTGGAGTGAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAG
CCACAAGCGCTTCCCCAGCACAGGAAGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCA
CTGGAACTCCCAGTCCAGCATGCCGTCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAG
CCCCACCCGACTGCACAGCCTCGCACTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGA
CACCGGGAGCCCCGACTTCTACACCCCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTC
GAGCTCGGAGCACTACTACCCGGCGCAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAG
GCAGCGGCAGCGGGCGGCGGGCGCACTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGG
GGGCGCGGGGGGCGGTGTGTACCTGCACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGG
CGCCACGCCCGTGGTGGTGCGCAGCCTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACAC
GGCGGGCGGCCTGTTCAAGGAGAGCTGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCT
GCGGACTCCGTCGCTGGGCCGCGAGGGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCG
TTCCACCGCCTCGCACAAGGAGCACAGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCA
GAGCACCTTCGTGGCGCACAGCAGGGTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTC
GACACCGTCAAGTGAAATTGGAGCCACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACC

>29764_29764_3_FBXO18-FRMD4A_FBXO18_chr10_5932309_ENST00000362091_FRMD4A_chr10_13717044_ENST00000378503_length(amino acids)=654AA_BP=
MLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQIT
EAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLH
SPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQN
SPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDD
CSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYLHSQSQPSSQYRIKE
YPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGREGAHDKGAGRAAVSD
ELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FBXO18-FRMD4A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FBXO18-FRMD4A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FBXO18-FRMD4A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource