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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:FDFT1-TNKS (FusionGDB2 ID:30051)

Fusion Gene Summary for FDFT1-TNKS

Fusion gene summary

Fusion gene information	Fusion gene name: FDFT1-TNKS
	Fusion gene ID: 30051
		Hgene	Tgene
	Gene symbol	FDFT1	TNKS
	Gene ID	2222	8658
	Gene name	farnesyl-diphosphate farnesyltransferase 1	tankyrase
	Synonyms	DGPT\|ERG9\|SQS\|SQSD\|SS	ARTD5\|PARP-5a\|PARP5A\|PARPL\|TIN1\|TINF1\|TNKS1\|pART5
	Cytomap	8p23.1	8p23.1
	Type of gene	protein-coding	protein-coding
	Description	squalene synthaseFPP:FPP farnesyltransferasepresqualene-di-diphosphate synthasesqualene synthetase	poly [ADP-ribose] polymerase tankyrase-1ADP-ribosyltransferase diphtheria toxin-like 5TANK1TNKS-1TRF1-interacting ankyrin-related ADP-ribose polymerase 1poly [ADP-ribose] polymerase 5Aprotein poly-ADP-ribosyltransferase tankyrase-1tankyrase Itanky
	Modification date	20200320	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000220584, ENST00000443614, ENST00000446331, ENST00000525777, ENST00000525900, ENST00000528643, ENST00000528812, ENST00000530664, ENST00000538689,	ENST00000518027, ENST00000522110, ENST00000310430, ENST00000518281, ENST00000520408,
Fusion gene scores	* DoF score	16 X 12 X 9=1728	8 X 9 X 6=432
	# samples	20	9
	** MAII score	log2(20/1728*10)=-3.11103131238874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(9/432*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: FDFT1 [Title/Abstract] AND TNKS [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	FDFT1(11660440)-TNKS(9562173), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	TNKS	GO:0000209	protein polyubiquitination	19759537\|21478859
Tgene	TNKS	GO:0006471	protein ADP-ribosylation	9822378\|15133513\|21270334
Tgene	TNKS	GO:0018105	peptidyl-serine phosphorylation	17026964
Tgene	TNKS	GO:0018107	peptidyl-threonine phosphorylation	17026964
Tgene	TNKS	GO:0032212	positive regulation of telomere maintenance via telomerase	12782650\|18221737
Tgene	TNKS	GO:0045944	positive regulation of transcription by RNA polymerase II	19245366
Tgene	TNKS	GO:0051973	positive regulation of telomerase activity	12782650
Tgene	TNKS	GO:0070212	protein poly-ADP-ribosylation	9822378\|16076287\|25043379
Tgene	TNKS	GO:0070213	protein auto-ADP-ribosylation	9822378\|15133513\|19759537\|21478859
Tgene	TNKS	GO:1904355	positive regulation of telomere capping	21531765
Tgene	TNKS	GO:1904743	negative regulation of telomeric DNA binding	9822378

Fusion gene breakpoints across FDFT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TNKS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-GC-A4ZW-01A	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+

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Fusion Gene ORF analysis for FDFT1-TNKS

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000220584	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
5CDS-3UTR	ENST00000443614	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
5CDS-intron	ENST00000220584	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
5CDS-intron	ENST00000443614	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
In-frame	ENST00000220584	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
In-frame	ENST00000220584	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
In-frame	ENST00000220584	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
In-frame	ENST00000443614	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
In-frame	ENST00000443614	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
In-frame	ENST00000443614	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000446331	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000446331	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000446331	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000525777	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000525777	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000525777	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000525900	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000525900	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000525900	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000528643	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000528643	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000528643	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000528812	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000528812	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000528812	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000530664	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000530664	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000530664	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000538689	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000538689	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3CDS	ENST00000538689	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3UTR	ENST00000446331	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3UTR	ENST00000525777	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3UTR	ENST00000525900	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3UTR	ENST00000528643	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3UTR	ENST00000528812	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3UTR	ENST00000530664	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-3UTR	ENST00000538689	ENST00000518027	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-intron	ENST00000446331	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-intron	ENST00000525777	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-intron	ENST00000525900	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-intron	ENST00000528643	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-intron	ENST00000528812	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-intron	ENST00000530664	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+
intron-intron	ENST00000538689	ENST00000522110	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000220584	FDFT1	chr8	11660440	+	ENST00000520408	TNKS	chr8	9562173	+	1152	321	222	1067	281
ENST00000220584	FDFT1	chr8	11660440	+	ENST00000310430	TNKS	chr8	9562173	+	8808	321	222	3197	991
ENST00000220584	FDFT1	chr8	11660440	+	ENST00000518281	TNKS	chr8	9562173	+	3391	321	222	3197	991
ENST00000443614	FDFT1	chr8	11660440	+	ENST00000520408	TNKS	chr8	9562173	+	1024	193	94	939	281
ENST00000443614	FDFT1	chr8	11660440	+	ENST00000310430	TNKS	chr8	9562173	+	8680	193	94	3069	991
ENST00000443614	FDFT1	chr8	11660440	+	ENST00000518281	TNKS	chr8	9562173	+	3263	193	94	3069	991

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000220584	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+	0.003045551	0.99695444
ENST00000220584	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+	0.000251723	0.9997483
ENST00000220584	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+	0.002204993	0.997795
ENST00000443614	ENST00000520408	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+	0.001958652	0.9980413
ENST00000443614	ENST00000310430	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+	0.000208535	0.99979144
ENST00000443614	ENST00000518281	FDFT1	chr8	11660440	+	TNKS	chr8	9562173	+	0.001738184	0.99826187

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Fusion Genomic Features for FDFT1-TNKS

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
FDFT1	chr8	11660440	+	TNKS	chr8	9562172	+	1.25E-08	1
FDFT1	chr8	11660440	+	TNKS	chr8	9562172	+	1.25E-08	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FDFT1-TNKS

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:11660440/chr8:9562173)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

1030_1089

369

1328.0

Domain

SAM

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

1112_1317

369

1328.0

Domain

PARP catalytic

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

368_397

369

1328.0

Repeat

ANK 6

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

401_430

369

1328.0

Repeat

ANK 7

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

434_463

369

1328.0

Repeat

ANK 8

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

521_553

369

1328.0

Repeat

ANK 9

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

557_586

369

1328.0

Repeat

ANK 10

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

590_619

369

1328.0

Repeat

ANK 11

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

621_647

369

1328.0

Repeat

ANK 12

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

649_679

369

1328.0

Repeat

ANK 13

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

683_712

369

1328.0

Repeat

ANK 14

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

716_745

369

1328.0

Repeat

ANK 15

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

749_778

369

1328.0

Repeat

ANK 16

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

782_810

369

1328.0

Repeat

ANK 17

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

836_865

369

1328.0

Repeat

ANK 18

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

869_898

369

1328.0

Repeat

ANK 19

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

902_931

369

1328.0

Repeat

ANK 20

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

935_964

369

1328.0

Repeat

ANK 21

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

FDFT1

chr8:11660440

chr8:9562173

ENST00000220584

284_304

418.0

Transmembrane

Helical

Hgene

FDFT1

chr8:11660440

chr8:9562173

ENST00000220584

384_404

418.0

Transmembrane

Helical

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

109_161

369

1328.0

Compositional bias

Ser-rich

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

20_83

369

1328.0

Compositional bias

Pro-rich

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

9_14

369

1328.0

Compositional bias

Poly-His

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

181_209

369

1328.0

Repeat

ANK 1

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

215_244

369

1328.0

Repeat

ANK 2

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

248_277

369

1328.0

Repeat

ANK 3

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

281_310

369

1328.0

Repeat

ANK 4

Tgene

TNKS

chr8:11660440

chr8:9562173

ENST00000310430

335_364

369

1328.0

Repeat

ANK 5

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Fusion Gene Sequence for FDFT1-TNKS

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>30051_30051_1_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000310430_length(transcript)=8808nt_BP=321nt
AATCAGCGCCCGTCAGCCCACCCCACGAGGCCGCAGCTAGCCCCGCTGGCGGCCGAGGCCGGTTGAAGTGGGCGGAGCGGCGGGCGGGGC
GTCGCCGTACTAGGCCTGCCCCCTGTCCGGCCAGCCCCTCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGC
AGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGCCAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTG
GTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCCCAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTT
CGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGTTCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATAT
GGACATTATGAAGTCACAGAACTGCTACTAAAGCATGGAGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCT
GCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACTTAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTG
GATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGACTTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTA
GCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAATTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCT
CTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACTTAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTG
CATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGAAGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAG
ACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCAGACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTA
CAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGTGCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTAT
CGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAACTGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGC
CGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAACCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCC
AAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTGTTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCT
GTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCATGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACAT
GGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATACACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGA
GGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTGCCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGAC
ACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGCAGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGAT
GTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCATAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATAC
AACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTACTCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTC
CTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGAAGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTG
ATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTTTAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACC
CCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCTCACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGAT
GGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGCTGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACAC
CTTCGGGATATCTTTGAAACAGAACAGATTACACTAGATGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCA
TATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAGACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTT
AATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGATAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACAC
AGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATACAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTC
TGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAACCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATT
ATTCATAAAGGGTTTGATGAGCGACATGCATACATAGGAGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAAC
CAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCCTACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGT
AGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCACCATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCG
AGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTACAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAG
CCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCAGAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGG
ACTGGATTACAGAGGATTGTTTCTAATAACAACATCAATATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAG
CATTGCTATAGTGATGAATAGTATGAGTAACTGATACATACTCAACTGCTACTGTTCCCTTTGAGGAAATGTTTACAGGGGCGGCCTTTT
AACATATCTCAGGCTCATTTTCATTGCAATTATCCATTTCTAAAACAAGATTGCTTCGATCTAGACTTGGAAATGGAAAATAAGAAAACC
AATGCTTTTTCAAATGTTCACAATTCACACACTACATTTGTTTTGTTATGCATGACGTGTCTATAACAAATATACACATACGACAGGCAA
CAAGCTTGTTTTTGATTTGCCAGACATGCATCATTGGCTATTGTTTGTTTGTTTTTTGTTTTTTTGTGTTTTTTGGGTTACTTTGAAAAT
GAGCCAGAGCCTTCTTGAGGATATTTTGCACAAAGTCACGCTGACAAAATCATTAGCAGTGCAACCCAAGCTTCTGGCTGAGCAAGATTC
AGTTTCCACTTTTTAAAATTTTTTTATTTTGCTCTGTAGCTGCACTTCTCGTTATCATAAATTGAGATGAAAAGGAAAAAACATCAAGTT
TTAGTACCTTTTTATGAATTGGCCTATCTTACAAGAGAAGGGCACAAACACCAACCTGACTTAGGAACGCCTAAATTCAGAGAAGTCAAA
GCCGGTGAAGGCCACTTGCTCTTTCCAACACAAGCCTGCCACAGAGGTCTTCGGGACAGTACTGGAGATGCAGGTTGACACGGGCTTGAG
TTCCAAGGTGAAAAAACTGGGGAGGCTGTGAAGGAAGAGCTGCATTAAGGAGGGTGAGGAGCGTGTGGTTCTGTATCATGGCAGCCCCAA
TGGATCCAGGGGATGCCTCCAAAAAATACATGCTTCCCTTCCCTTAATCTGTACTGTTGGGATTGTTACCCCTCCAAATTAGCTGCCTTA
TTTCAAAAGTCAGTGAAATTACTGCACTTGATGAGGGTCACAAAAATACCACTTGATTGTTTCTTTAGTTGAGAATGCTGGGATTCAGAC
TCGAATAGTGGATAGATACACACAAATGCAAGGACTTTTTTGTTTACTCCAGATTTGGGGTTTATTTTGAGTGGCATGCTTCAAATAGTT
CATAAAGATCCTTGCATTAAATTTCTGAACCATTTCTTCAAACTTCTTAGTGTGTTTAGACAAGGAGAACAAAAATTGAAACCAAAGCCC
TTTCTGTTATTTTTTCAATGAAGGTGAGAAAGAAATACCATACAATTTTCTTTGTGAAATTACTGTTTATTTTCATCAACATTTACCAAG
TGCCATTGACATTTATAAAAAAAAATGATCCTTTATAGTTCTTACACTTGCCCTTTTCACCTTAACTGAATATGAATTGAGTGCACTAAC
TTATTTACTTGATATACTGTGCATCTACTCTGCTTTGAAGCGAAAGAAATATAAACACGAGGAGGAATAGGAAAGACAGTGTGACACAAA
CTTGCCATTGCAATTCAAAGCCCTGAAAACGATGGGTTTAATGCAAGGTGATTAAGCTGTGACCTCCTTTAATCTCCTGAAGCAAAATAA
AATGGTTACATGCAAAACTTCTAGAAATAGACTCTTAAAATATATACATTTTGCTTTGATTTTGGCTTCAACCCAGTGCTGGAACTAGGC
ATCCAGACTAGTTTGAATGTTTGTAGCTGAATTTTTATGGGTCCTCAAAATTAAATCGAGAATTAGCCTCAGTTGTTGCTTCTTTTGAAG
TTTCAGTGACCCAAGCTGGGTGTTTGTGTCTTGGCTACTTGTTTAATAGCACTAGAATTCCAGGTGAAGCTTTGAGAGTTGATATTCATT
AAGAGGGCTTTTTTTCCCCTTCTTTCCTTCTCTTTTGCTGTAACAAAGGGTTGAAGAAATTGCCATCTGTGTAGTTTTCAGTAGCTGTCA
AGTGTGTCTTACTTACCTTCCCCCAGACGTAGTTTAAAATGGTAAACACAGCTGTGATTTTTAGTTAAGTAAAAGAGTTAATATGATATA
GATATGGAAAGCTTTATGGCTTCATTAAAAAGATAAACCACTACCTAACTGTGGTTGTATGTTGTTTCCATCATACTAACTAGATGAATG
GATGCGCCAGTTTTCATCTTGGTCCTTACACTTGAGAAGTTAAACTGTGGTTCAGTATTTAAACTGCCAGTGTTATACGTCTCATGCTCT
GTGTGCCAGGTGAAGGTACTGTGTAAGGAAGACATTTGCGGTGCTTCTTGTCCTATAATGATTCAAGTATATAGTAGTTCTTGAAAGAGT
GTGCATATATTACTCATCTGCTTAAGAGAGTGGGTTAATGGATATATCAGAGGAGCCAAATACATTTTTTTCAGAACTTGAAAACCAAAG
GTCATCATGAGTGCACTCAAAAGTTAGGACAAGTTTATTACATTTGGGATTTTCATCTGTAGCCGTATGAAGAACCCTTTCCAATATAAA
AGCATGGCATTAAATTAGGCTGAAGTCTTTTATTTTTTGTATATGTACTATATAGAAATACTAGCAAGTTAGGATCATCCAATATGGCCT
ACCCCGAAATGGCCCCTCTGTTTCCCTAACCACATGGAAGAAAGAATCTGAACGTCTCCACCGGCTCTACCCGAGTTCCAAAACTAAAGG
GCTTCTCCAGACCTGATGGTTCCAGTTTACCTGCTGTTGGCCTGCTGGATACTTGACTCAGGCATAAATTAAGTGCCCTGGTCCCGAACT
TTCTCCCTGTATTTGACCTCCTTCCCTCTTTCCTAAATTACTAGTCTGGAATTAAAATTAGCTCCAGCAATGACCTTTGACTCCATTCAT
TTTCTCCTCATCTTGGGTCTTAAAAAAGGAGACCAGATACCTCCTAGCTTTTGTATCACAACCAGGAATGGGTATTAGGCCTCATGCGCT
TTGCTCAGAACACTGCCGCTTTGTTAACAAATGACAGCATGGAACCCAGAGTTTTGATTCGATGCAAAATAACAGCAGTGCAACCAGGAT
TCTTGTTTTCCTTTTCCTTCTTGGAGTTTGGAATTTCTAGCTTTTCAAGCAGCATAAGTAGAATCAACATTAGGATGTTTTCATGAAATA
GCATCCTTATACTTCTTTGAGCTTGATGTTAGTGGCTAGACTGATTTCCCTTTGCTCTCAAAATACAAAGTGCATTGAAGTATACAGAGA
AATGCCTGAATATGGCAAGCAAATAATGTAGATTAACATTCTATTATTGTATCCGTTTTACAAAAAATAAAATTTTGATATATGCCGGAG
AACGGCATTAGAATGCAATAAGTTGTCTAGGTTTTTCTGTTTCAGTGTCTCTCCCAATGGCACGAAGGGTTATTGGGCATTGTCCCCACC
CCCGCCTTTTTAACATGTGCACTATCTGGATTCCTGTAAATGGCCTTGCAAACAGAAGTGGTGTGTATTTTCAAGCACCTTTCCCCCATT
GTATCCGAATCCCTCTTGTGTGATATCTGTGACAAATAGCCTTCTTCTTGTGTTTTCTGTTGGACTAATTGTCTCACGTAAAGCTATAGA
CCTTACTAATTTGGCAGGTATTCAAAACTGCCATTAAGATAGGATTTCATGTCAGATACGTATTTAAAGAGTAAAGTCAAATTTGTTTAA
TGTCAGATCAGTGACAGAAGTGAAAAGAAAGTAATTGTGAAAGTGATGTTTGAGCTATTGTACACATCTAGCATATGGAAAGCAAATGCA
CTCGAAAACTACTATTCTAGAACATGAGGCTTCTTCAGCAACTTGTGCACTCTGCCATTAATAAATTAAATTTTTCCCCTCTAGAAAGCC
TTAACTATGGCGGAAACTTTTTAACCTTTTATATTTTAATAAATAAAACATTGTAGTCCCATTTCTTAGTGTTTGAAAGGTGTGTCAGTG
AGTCGGCCATGTCTCCATGTGTTTCAGACCTGTTCATCTTATTTTATGATGGTATATTTCATAAGTAATATTCCCTTACATGCAATGGAG
CTGATTAAAATTAATCCATTTCAATTTCTCCATATTGGAACTTCCTCAGCTACCAGATTTCTGGTTTGGAGAAGTGCTGGAAAGATTTCA
AAGCCTATTCAGTTGTGTATGTGGGGATACGACAGCAACTGTGATACCTTGTAGAATATGAGTGATATGCAAGCTGTGTTTTTTAATTGT
TTTAAAATGTAAATTATGGTTATGCTAAAGTGAAAACCTAGAGGAAGCTAATGATTTTATATACTTTGCACGACCAAATATGGTCGTAGT
ATGACGAGTTTTATACATTGCCAGAGAGTTCTGCCTCCTCTGAAATAACATTCGCACTGTAGATTGCATTTCGGCTTTTCCTCCTTTCAC
ATTCTTTTTTGCTTTACACTTCACGTCTTCGCACCTGCCCTACCTCCCATCCTTTCAAAGAGGTTTCTTTCACGTTCCAGAATTCAGATT
GTTCTGTGATTTCTTTTACATCAGTCTACCCATTTCTGCAGGCAGCCCTGAAAGCCCTTGTGTTGATTCAGAGTGTTTGCAGAGAAATGC
AGTTGAACCCTGGTAGTGGGGTGTCCCTCACACACCCGCGCACCCCTCCCAAAGTTCAGGATGAAAGGCTAGAAAACCCATTCAAAGTTA
GGAAAGAACACAGATCTTTGAGGCCGATAGCCTAGACCTAGAAGATGACCTTGAGTATGTAAACATTGTCTCCGTGACACAAAACACTGA
AACTCTTCATGTGCATATAACACCTGCTTCTGCTCCCATTGTTTCAAGCTCATCTTATCTTTGTAGTAGTAATGTTTGTCTTTGATACCT
ACAAACTAAAAAGGTACTTTTATCAAGGTTTCTCAAAACATTTACAAAACCAGCTTTGAGAAAATGTTATGTTGCCTGGCAACAGCACTC
GGAGTAGTAATTGTGTTTTCTCATTGTGATGTTGGTCTGTGTGAGCAACCAGTGTAGTGACTCTTTGGTTCATTATTCGTGTTGTTTTTA
TTTTTAGTCTCTGTGTGACCCAACAGTGGCAGGGGTTACAACCCCCTCTCCTTTCTTTTTTGTATTTATCTATTTGTAGGATTGTCAGAT
CAAGTACAAGATGCCCAGTTAAGTTTGAATTTCAGAGAAACAATTTCACGTTAAGAATGTTTCATGCAATATTTGGCATATATTTACAGT
AAAAGCATTCATTATTTGTCTGAAATTCAAATTTAACTGAGCATGCTGGTTTTTCTCATTGTTTGGTTTTTCTAAATCTGGCAATCCTAC
AGCTGTGGTCATGGGAAATCACCTACAGCATGTTAAAGTCCTCTAGTCATCATCTCGTCACCTGAAATGGAAGTCCTTTTTCCCTCACCC
TCCACTTCTTTCCAAAGGAGGGCATCAAGGAACTTAACCTGCCTGCCTGGTGGGTTTCTATTTAAGACATCTTTGTGATTATATTTAACC

>30051_30051_1_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000310430_length(amino acids)=991AA_BP=317
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA
CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF
KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT
CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR
VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP
LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN
AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK
PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV
LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN
VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT
HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK

--------------------------------------------------------------
>30051_30051_2_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000518281_length(transcript)=3391nt_BP=321nt
AATCAGCGCCCGTCAGCCCACCCCACGAGGCCGCAGCTAGCCCCGCTGGCGGCCGAGGCCGGTTGAAGTGGGCGGAGCGGCGGGCGGGGC
GTCGCCGTACTAGGCCTGCCCCCTGTCCGGCCAGCCCCTCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGC
AGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGCCAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTG
GTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCCCAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTT
CGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGTTCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATAT
GGACATTATGAAGTCACAGAACTGCTACTAAAGCATGGAGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCT
GCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACTTAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTG
GATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGACTTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTA
GCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAATTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCT
CTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACTTAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTG
CATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGAAGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAG
ACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCAGACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTA
CAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGTGCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTAT
CGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAACTGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGC
CGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAACCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCC
AAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTGTTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCT
GTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCATGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACAT
GGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATACACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGA
GGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTGCCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGAC
ACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGCAGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGAT
GTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCATAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATAC
AACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTACTCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTC
CTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGAAGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTG
ATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTTTAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACC
CCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCTCACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGAT
GGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGCTGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACAC
CTTCGGGATATCTTTGAAACAGAACAGATTACACTAGATGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCA
TATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAGACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTT
AATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGATAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACAC
AGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATACAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTC
TGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAACCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATT
ATTCATAAAGGGTTTGATGAGCGACATGCATACATAGGAGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAAC
CAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCCTACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGT
AGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCACCATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCG
AGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTACAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAG
CCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCAGAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGG
ACTGGATTACAGAGGATTGTTTCTAATAACAACATCAATATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAG

>30051_30051_2_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000518281_length(amino acids)=991AA_BP=317
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA
CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF
KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT
CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR
VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP
LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN
AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK
PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV
LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN
VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT
HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK

--------------------------------------------------------------
>30051_30051_3_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000520408_length(transcript)=1152nt_BP=321nt
AATCAGCGCCCGTCAGCCCACCCCACGAGGCCGCAGCTAGCCCCGCTGGCGGCCGAGGCCGGTTGAAGTGGGCGGAGCGGCGGGCGGGGC
GTCGCCGTACTAGGCCTGCCCCCTGTCCGGCCAGCCCCTCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGC
AGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGCCAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTG
GTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCCCAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTT
CGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGTTCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATAT
GGACATTATGAAGTCACAGAACTGCTACTAAAGCATGGAGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCT
GCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACTTAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTG
GATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGACTTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTA
GCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAATTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCT
CTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACTTAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTG
CATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGAAGTTCTGCATAAGCATGGCGCCAAGGTGAGGCACACACCTGAGCAGAGTGCC
AGACTCAGCACTGAGCAGCCAGCTGCTCTTAACACTGCTTCTCTCTCTCCGATTTTTCTGAAGAAACTAATTTTATAAAGGACTATTAGT

>30051_30051_3_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000220584_TNKS_chr8_9562173_ENST00000520408_length(amino acids)=281AA_BP=33
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA
CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF
KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKVRHTPEQSARLSTEQPAALNTAS

--------------------------------------------------------------
>30051_30051_4_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000310430_length(transcript)=8680nt_BP=193nt
TCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGCAGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGC
CAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCC
CAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTTCGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGT
TCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATATGGACATTATGAAGTCACAGAACTGCTACTAAAGCATGG
AGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCTGCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACT
TAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTGGATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGAC
TTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTAGCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAA
TTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCTCTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACT
TAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTGCATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGA
AGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAGACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCA
GACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTACAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGT
GCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTATCGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAAC
TGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGCCGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAA
CCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCCAAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTG
TTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCTGTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCA
TGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACATGGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATAC
ACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGAGGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTG
CCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGACACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGC
AGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGATGTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCA
TAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATACAACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTAC
TCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTCCTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGA
AGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTGATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTT
TAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACCCCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCT
CACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGATGGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGC
TGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACACCTTCGGGATATCTTTGAAACAGAACAGATTACACTAGA
TGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCATATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAG
ACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTTAATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGA
TAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACACAGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATA
CAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTCTGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAA
CCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATTATTCATAAAGGGTTTGATGAGCGACATGCATACATAGG
AGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAACCAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCC
TACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGTAGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCAC
CATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCGAGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTA
CAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAGCCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCA
GAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGGACTGGATTACAGAGGATTGTTTCTAATAACAACATCAA
TATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAGCATTGCTATAGTGATGAATAGTATGAGTAACTGATACA
TACTCAACTGCTACTGTTCCCTTTGAGGAAATGTTTACAGGGGCGGCCTTTTAACATATCTCAGGCTCATTTTCATTGCAATTATCCATT
TCTAAAACAAGATTGCTTCGATCTAGACTTGGAAATGGAAAATAAGAAAACCAATGCTTTTTCAAATGTTCACAATTCACACACTACATT
TGTTTTGTTATGCATGACGTGTCTATAACAAATATACACATACGACAGGCAACAAGCTTGTTTTTGATTTGCCAGACATGCATCATTGGC
TATTGTTTGTTTGTTTTTTGTTTTTTTGTGTTTTTTGGGTTACTTTGAAAATGAGCCAGAGCCTTCTTGAGGATATTTTGCACAAAGTCA
CGCTGACAAAATCATTAGCAGTGCAACCCAAGCTTCTGGCTGAGCAAGATTCAGTTTCCACTTTTTAAAATTTTTTTATTTTGCTCTGTA
GCTGCACTTCTCGTTATCATAAATTGAGATGAAAAGGAAAAAACATCAAGTTTTAGTACCTTTTTATGAATTGGCCTATCTTACAAGAGA
AGGGCACAAACACCAACCTGACTTAGGAACGCCTAAATTCAGAGAAGTCAAAGCCGGTGAAGGCCACTTGCTCTTTCCAACACAAGCCTG
CCACAGAGGTCTTCGGGACAGTACTGGAGATGCAGGTTGACACGGGCTTGAGTTCCAAGGTGAAAAAACTGGGGAGGCTGTGAAGGAAGA
GCTGCATTAAGGAGGGTGAGGAGCGTGTGGTTCTGTATCATGGCAGCCCCAATGGATCCAGGGGATGCCTCCAAAAAATACATGCTTCCC
TTCCCTTAATCTGTACTGTTGGGATTGTTACCCCTCCAAATTAGCTGCCTTATTTCAAAAGTCAGTGAAATTACTGCACTTGATGAGGGT
CACAAAAATACCACTTGATTGTTTCTTTAGTTGAGAATGCTGGGATTCAGACTCGAATAGTGGATAGATACACACAAATGCAAGGACTTT
TTTGTTTACTCCAGATTTGGGGTTTATTTTGAGTGGCATGCTTCAAATAGTTCATAAAGATCCTTGCATTAAATTTCTGAACCATTTCTT
CAAACTTCTTAGTGTGTTTAGACAAGGAGAACAAAAATTGAAACCAAAGCCCTTTCTGTTATTTTTTCAATGAAGGTGAGAAAGAAATAC
CATACAATTTTCTTTGTGAAATTACTGTTTATTTTCATCAACATTTACCAAGTGCCATTGACATTTATAAAAAAAAATGATCCTTTATAG
TTCTTACACTTGCCCTTTTCACCTTAACTGAATATGAATTGAGTGCACTAACTTATTTACTTGATATACTGTGCATCTACTCTGCTTTGA
AGCGAAAGAAATATAAACACGAGGAGGAATAGGAAAGACAGTGTGACACAAACTTGCCATTGCAATTCAAAGCCCTGAAAACGATGGGTT
TAATGCAAGGTGATTAAGCTGTGACCTCCTTTAATCTCCTGAAGCAAAATAAAATGGTTACATGCAAAACTTCTAGAAATAGACTCTTAA
AATATATACATTTTGCTTTGATTTTGGCTTCAACCCAGTGCTGGAACTAGGCATCCAGACTAGTTTGAATGTTTGTAGCTGAATTTTTAT
GGGTCCTCAAAATTAAATCGAGAATTAGCCTCAGTTGTTGCTTCTTTTGAAGTTTCAGTGACCCAAGCTGGGTGTTTGTGTCTTGGCTAC
TTGTTTAATAGCACTAGAATTCCAGGTGAAGCTTTGAGAGTTGATATTCATTAAGAGGGCTTTTTTTCCCCTTCTTTCCTTCTCTTTTGC
TGTAACAAAGGGTTGAAGAAATTGCCATCTGTGTAGTTTTCAGTAGCTGTCAAGTGTGTCTTACTTACCTTCCCCCAGACGTAGTTTAAA
ATGGTAAACACAGCTGTGATTTTTAGTTAAGTAAAAGAGTTAATATGATATAGATATGGAAAGCTTTATGGCTTCATTAAAAAGATAAAC
CACTACCTAACTGTGGTTGTATGTTGTTTCCATCATACTAACTAGATGAATGGATGCGCCAGTTTTCATCTTGGTCCTTACACTTGAGAA
GTTAAACTGTGGTTCAGTATTTAAACTGCCAGTGTTATACGTCTCATGCTCTGTGTGCCAGGTGAAGGTACTGTGTAAGGAAGACATTTG
CGGTGCTTCTTGTCCTATAATGATTCAAGTATATAGTAGTTCTTGAAAGAGTGTGCATATATTACTCATCTGCTTAAGAGAGTGGGTTAA
TGGATATATCAGAGGAGCCAAATACATTTTTTTCAGAACTTGAAAACCAAAGGTCATCATGAGTGCACTCAAAAGTTAGGACAAGTTTAT
TACATTTGGGATTTTCATCTGTAGCCGTATGAAGAACCCTTTCCAATATAAAAGCATGGCATTAAATTAGGCTGAAGTCTTTTATTTTTT
GTATATGTACTATATAGAAATACTAGCAAGTTAGGATCATCCAATATGGCCTACCCCGAAATGGCCCCTCTGTTTCCCTAACCACATGGA
AGAAAGAATCTGAACGTCTCCACCGGCTCTACCCGAGTTCCAAAACTAAAGGGCTTCTCCAGACCTGATGGTTCCAGTTTACCTGCTGTT
GGCCTGCTGGATACTTGACTCAGGCATAAATTAAGTGCCCTGGTCCCGAACTTTCTCCCTGTATTTGACCTCCTTCCCTCTTTCCTAAAT
TACTAGTCTGGAATTAAAATTAGCTCCAGCAATGACCTTTGACTCCATTCATTTTCTCCTCATCTTGGGTCTTAAAAAAGGAGACCAGAT
ACCTCCTAGCTTTTGTATCACAACCAGGAATGGGTATTAGGCCTCATGCGCTTTGCTCAGAACACTGCCGCTTTGTTAACAAATGACAGC
ATGGAACCCAGAGTTTTGATTCGATGCAAAATAACAGCAGTGCAACCAGGATTCTTGTTTTCCTTTTCCTTCTTGGAGTTTGGAATTTCT
AGCTTTTCAAGCAGCATAAGTAGAATCAACATTAGGATGTTTTCATGAAATAGCATCCTTATACTTCTTTGAGCTTGATGTTAGTGGCTA
GACTGATTTCCCTTTGCTCTCAAAATACAAAGTGCATTGAAGTATACAGAGAAATGCCTGAATATGGCAAGCAAATAATGTAGATTAACA
TTCTATTATTGTATCCGTTTTACAAAAAATAAAATTTTGATATATGCCGGAGAACGGCATTAGAATGCAATAAGTTGTCTAGGTTTTTCT
GTTTCAGTGTCTCTCCCAATGGCACGAAGGGTTATTGGGCATTGTCCCCACCCCCGCCTTTTTAACATGTGCACTATCTGGATTCCTGTA
AATGGCCTTGCAAACAGAAGTGGTGTGTATTTTCAAGCACCTTTCCCCCATTGTATCCGAATCCCTCTTGTGTGATATCTGTGACAAATA
GCCTTCTTCTTGTGTTTTCTGTTGGACTAATTGTCTCACGTAAAGCTATAGACCTTACTAATTTGGCAGGTATTCAAAACTGCCATTAAG
ATAGGATTTCATGTCAGATACGTATTTAAAGAGTAAAGTCAAATTTGTTTAATGTCAGATCAGTGACAGAAGTGAAAAGAAAGTAATTGT
GAAAGTGATGTTTGAGCTATTGTACACATCTAGCATATGGAAAGCAAATGCACTCGAAAACTACTATTCTAGAACATGAGGCTTCTTCAG
CAACTTGTGCACTCTGCCATTAATAAATTAAATTTTTCCCCTCTAGAAAGCCTTAACTATGGCGGAAACTTTTTAACCTTTTATATTTTA
ATAAATAAAACATTGTAGTCCCATTTCTTAGTGTTTGAAAGGTGTGTCAGTGAGTCGGCCATGTCTCCATGTGTTTCAGACCTGTTCATC
TTATTTTATGATGGTATATTTCATAAGTAATATTCCCTTACATGCAATGGAGCTGATTAAAATTAATCCATTTCAATTTCTCCATATTGG
AACTTCCTCAGCTACCAGATTTCTGGTTTGGAGAAGTGCTGGAAAGATTTCAAAGCCTATTCAGTTGTGTATGTGGGGATACGACAGCAA
CTGTGATACCTTGTAGAATATGAGTGATATGCAAGCTGTGTTTTTTAATTGTTTTAAAATGTAAATTATGGTTATGCTAAAGTGAAAACC
TAGAGGAAGCTAATGATTTTATATACTTTGCACGACCAAATATGGTCGTAGTATGACGAGTTTTATACATTGCCAGAGAGTTCTGCCTCC
TCTGAAATAACATTCGCACTGTAGATTGCATTTCGGCTTTTCCTCCTTTCACATTCTTTTTTGCTTTACACTTCACGTCTTCGCACCTGC
CCTACCTCCCATCCTTTCAAAGAGGTTTCTTTCACGTTCCAGAATTCAGATTGTTCTGTGATTTCTTTTACATCAGTCTACCCATTTCTG
CAGGCAGCCCTGAAAGCCCTTGTGTTGATTCAGAGTGTTTGCAGAGAAATGCAGTTGAACCCTGGTAGTGGGGTGTCCCTCACACACCCG
CGCACCCCTCCCAAAGTTCAGGATGAAAGGCTAGAAAACCCATTCAAAGTTAGGAAAGAACACAGATCTTTGAGGCCGATAGCCTAGACC
TAGAAGATGACCTTGAGTATGTAAACATTGTCTCCGTGACACAAAACACTGAAACTCTTCATGTGCATATAACACCTGCTTCTGCTCCCA
TTGTTTCAAGCTCATCTTATCTTTGTAGTAGTAATGTTTGTCTTTGATACCTACAAACTAAAAAGGTACTTTTATCAAGGTTTCTCAAAA
CATTTACAAAACCAGCTTTGAGAAAATGTTATGTTGCCTGGCAACAGCACTCGGAGTAGTAATTGTGTTTTCTCATTGTGATGTTGGTCT
GTGTGAGCAACCAGTGTAGTGACTCTTTGGTTCATTATTCGTGTTGTTTTTATTTTTAGTCTCTGTGTGACCCAACAGTGGCAGGGGTTA
CAACCCCCTCTCCTTTCTTTTTTGTATTTATCTATTTGTAGGATTGTCAGATCAAGTACAAGATGCCCAGTTAAGTTTGAATTTCAGAGA
AACAATTTCACGTTAAGAATGTTTCATGCAATATTTGGCATATATTTACAGTAAAAGCATTCATTATTTGTCTGAAATTCAAATTTAACT
GAGCATGCTGGTTTTTCTCATTGTTTGGTTTTTCTAAATCTGGCAATCCTACAGCTGTGGTCATGGGAAATCACCTACAGCATGTTAAAG
TCCTCTAGTCATCATCTCGTCACCTGAAATGGAAGTCCTTTTTCCCTCACCCTCCACTTCTTTCCAAAGGAGGGCATCAAGGAACTTAAC
CTGCCTGCCTGGTGGGTTTCTATTTAAGACATCTTTGTGATTATATTTAACCTGCAATTGTGCTTTGGCTTAATGTCTAGCTCACTGTAC

>30051_30051_4_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000310430_length(amino acids)=991AA_BP=317
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA
CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF
KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT
CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR
VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP
LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN
AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK
PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV
LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN
VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT
HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK

--------------------------------------------------------------
>30051_30051_5_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000518281_length(transcript)=3263nt_BP=193nt
TCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGCAGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGC
CAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCC
CAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTTCGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGT
TCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATATGGACATTATGAAGTCACAGAACTGCTACTAAAGCATGG
AGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCTGCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACT
TAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTGGATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGAC
TTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTAGCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAA
TTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCTCTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACT
TAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTGCATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGA
AGTTCTGCATAAGCATGGCGCCAAGATGAATGCACTGGACACCCTTGGTCAGACTGCTTTGCATAGAGCCGCCCTAGCAGGTCACCTGCA
GACCTGCCGCCTCCTGCTGAGTTACGGCTCTGACCCCTCCATCATCTCCTTACAAGGCTTCACAGCAGCACAGATGGGCAATGAAGCAGT
GCAGCAGATTCTGAGTGAGAGTACACCTATACGTACTTCTGATGTTGATTATCGACTCTTAGAGGCATCTAAAGCTGGAGACTTGGAAAC
TGTGAAGCAACTTTGCAGCTCTCAAAATGTGAATTGTAGAGACTTAGAGGGCCGGCATTCCACGCCCTTACACTTCGCAGCAGGCTACAA
CCGCGTGTCTGTTGTAGAGTACCTGCTACACCACGGTGCCGATGTCCATGCCAAAGACAAGGGTGGCTTGGTGCCCCTTCATAATGCCTG
TTCATATGGACACTATGAGGTGGCTGAGCTTTTAGTAAGGCATGGGGCTTCTGTCAATGTGGCGGACTTATGGAAATTTACCCCTCTCCA
TGAAGCAGCAGCTAAAGGAAAGTATGAAATCTGCAAGCTCCTTTTAAAACATGGAGCAGATCCAACTAAAAAGAACAGAGATGGAAATAC
ACCTTTGGATTTGGTAAAGGAAGGAGACACAGATATTCAGGACTTACTGAGAGGGGATGCTGCTTTGTTGGATGCTGCCAAGAAGGGCTG
CCTGGCAAGAGTGCAGAAGCTCTGTACCCCAGAGAATATCAACTGCAGAGACACCCAGGGCAGAAATTCAACCCCTCTGCACCTGGCAGC
AGGCTATAATAACCTGGAAGTAGCTGAATATCTTCTAGAGCATGGAGCTGATGTTAATGCCCAGGACAAGGGTGGTTTAATTCCTCTTCA
TAATGCGGCATCTTATGGGCATGTTGACATAGCGGCTTTATTGATAAAATACAACACGTGTGTAAATGCAACAGATAAGTGGGCGTTTAC
TCCCCTCCATGAAGCAGCCCAGAAAGGAAGGACGCAGCTGTGCGCCCTCCTCCTAGCGCATGGTGCAGACCCCACCATGAAGAACCAGGA
AGGCCAGACGCCTCTGGATCTGGCAACAGCTGACGATATCAGAGCTTTGCTGATAGATGCCATGCCCCCAGAGGCCTTACCTACCTGTTT
TAAACCTCAGGCTACTGTAGTGAGTGCCTCTCTGATCTCACCAGCATCCACCCCCTCCTGCCTCTCGGCTGCCAGCAGCATAGACAACCT
CACTGGCCCTTTAGCAGAGTTGGCCGTAGGAGGAGCCTCCAATGCAGGGGATGGCGCCGCGGGAACAGAAAGGAAGGAAGGAGAAGTTGC
TGGTCTTGACATGAATATCAGCCAATTTCTAAAAAGCCTTGGCCTTGAACACCTTCGGGATATCTTTGAAACAGAACAGATTACACTAGA
TGTGTTGGCTGATATGGGTCATGAAGAGTTGAAAGAAATAGGCATCAATGCATATGGGCACCGCCACAAATTAATCAAAGGAGTAGAAAG
ACTCTTAGGTGGACAACAAGGCACCAATCCTTATTTGACTTTTCACTGTGTTAATCAGGGAACGATTTTGCTGGATCTTGCTCCAGAAGA
TAAAGAATATCAGTCAGTGGAAGAAGAGATGCAAAGTACTATTCGAGAACACAGAGATGGTGGTAATGCTGGCGGCATCTTCAACAGATA
CAATGTCATTCGAATTCAAAAAGTTGTCAACAAGAAGTTGAGGGAGCGGTTCTGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAA
CCATCACAATGAGCGCATGTTGTTTCATGGTTCTCCTTTCATTAATGCCATTATTCATAAAGGGTTTGATGAGCGACATGCATACATAGG
AGGAATGTTTGGGGCCGGGATTTATTTTGCTGAAAACTCCTCAAAAAGCAACCAATATGTTTATGGAATTGGAGGAGGAACAGGCTGCCC
TACACACAAGGACAGGTCATGCTATATATGTCACAGACAAATGCTCTTCTGTAGAGTGACCCTTGGGAAATCCTTTCTGCAGTTTAGCAC
CATGAAAATGGCCCACGCGCCTCCAGGGCACCACTCAGTCATTGGTAGACCGAGCGTCAATGGGCTGGCATATGCTGAATATGTCATCTA
CAGAGGAGAACAGGCATACCCAGAGTATCTTATCACTTACCAGATCATGAAGCCAGAAGCCCCTTCCCAGACCGCAACAGCCGCAGAGCA
GAAGACCTAGTGAATGCCTGCTGGTGAAGGCCAGATCAGATTTCAACCTGGGACTGGATTACAGAGGATTGTTTCTAATAACAACATCAA
TATTCTAGAAGTCCCTGACAGCCTAGAAATAAGCTGTTTGTCTTCTATAAAGCATTGCTATAGTGATGAATAGTATGAGTAACTGATACA

>30051_30051_5_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000518281_length(amino acids)=991AA_BP=317
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA
CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF
KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT
CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR
VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP
LDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN
AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFK
PQATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMNISQFLKSLGLEHLRDIFETEQITLDV
LADMGHEELKEIGINAYGHRHKLIKGVERLLGGQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN
VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPT
HKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQK

--------------------------------------------------------------
>30051_30051_6_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000520408_length(transcript)=1024nt_BP=193nt
TCGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGCGCCTGGGGACCGCAGAGGTGAGAGTCGCGCCCGGGAGTCCGCCGCCTGCGC
CAGGATGGAGTTCGTGAAATGCCTTGGCCACCCCGAAGAGTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCC
CAAGATGGACCAGTCGACTCCTTTACATCTAGCAGCGGGCTACAACAGAGTTCGAATAGTTCAGCTTCTTCTTCAGCATGGTGCTGATGT
TCATGCAAAAGACAAAGGTGGACTTGTGCCTCTTCATAATGCATGTTCATATGGACATTATGAAGTCACAGAACTGCTACTAAAGCATGG
AGCTTGTGTTAATGCCATGGATCTCTGGCAGTTTACTCCACTGCACGAGGCTGCTTCCAAGAACCGTGTAGAAGTCTGCTCTTTGTTACT
TAGCCATGGCGCTGATCCTACATTAGTCAACTGCCATGGCAAAAGTGCTGTGGATATGGCTCCAACTCCGGAGCTTAGGGAGAGATTGAC
TTATGAATTTAAAGGTCATTCTTTACTACAAGCAGCCAGAGAAGCAGACTTAGCTAAAGTTAAAAAAACACTCGCTCTGGAAATCATTAA
TTTCAAACAACCGCAGTCTCATGAAACAGCACTGCACTGTGCTGTGGCCTCTCTGCATCCCAAACGTAAACAAGTGACAGAATTGTTACT
TAGAAAAGGAGCAAATGTTAATGAAAAAAATAAAGATTTCATGACTCCCCTGCATGTTGCAGCCGAAAGAGCCCATAATGATGTCATGGA
AGTTCTGCATAAGCATGGCGCCAAGGTGAGGCACACACCTGAGCAGAGTGCCAGACTCAGCACTGAGCAGCCAGCTGCTCTTAACACTGC
TTCTCTCTCTCCGATTTTTCTGAAGAAACTAATTTTATAAAGGACTATTAGTTCGTACTTAAATTCATGGATTCTCCTATAAAGCTGATT

>30051_30051_6_FDFT1-TNKS_FDFT1_chr8_11660440_ENST00000443614_TNKS_chr8_9562173_ENST00000520408_length(amino acids)=281AA_BP=33
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA
CVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF
KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKVRHTPEQSARLSTEQPAALNTAS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for FDFT1-TNKS

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for FDFT1-TNKS

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for FDFT1-TNKS

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source