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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:FGD4-VPS13D (FusionGDB2 ID:30173) |
Fusion Gene Summary for FGD4-VPS13D |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FGD4-VPS13D | Fusion gene ID: 30173 | Hgene | Tgene | Gene symbol | FGD4 | VPS13D | Gene ID | 121512 | 55187 |
| Gene name | FYVE, RhoGEF and PH domain containing 4 | vacuolar protein sorting 13 homolog D | |
| Synonyms | CMT4H|FRABP|ZFYVE6 | SCAR4 | |
| Cytomap | 12p11.21 | 1p36.22-p36.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | FYVE, RhoGEF and PH domain-containing protein 4FGD1 family, member 4FGD1-related F-actin-binding proteinactin-filament binding protein frabinzinc finger FYVE domain-containing protein 6 | vacuolar protein sorting-associated protein 13Dvacuolar protein sorting 13D | |
| Modification date | 20200328 | 20200313 | |
| UniProtAcc | Q96M96 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000427716, ENST00000472289, ENST00000525053, ENST00000531134, ENST00000534526, ENST00000546442, ENST00000266482, ENST00000381025, ENST00000473513, | ENST00000356315, ENST00000358136, ENST00000471923, ENST00000496628, ENST00000543710, ENST00000543766, | |
| Fusion gene scores | * DoF score | 19 X 13 X 13=3211 | 8 X 10 X 5=400 |
| # samples | 22 | 11 | |
| ** MAII score | log2(22/3211*10)=-3.86744723620111 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/400*10)=-1.86249647625006 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FGD4 [Title/Abstract] AND VPS13D [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | FGD4(32735401)-VPS13D(12516054), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | FGD4-VPS13D seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. FGD4-VPS13D seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across FGD4 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across VPS13D (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LIHC | TCGA-KR-A7K8-01A | FGD4 | chr12 | 32735401 | - | VPS13D | chr1 | 12516054 | + |
| ChimerDB4 | LIHC | TCGA-KR-A7K8-01A | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| ChiTaRS5.0 | N/A | DB304604 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
Top |
Fusion Gene ORF analysis for FGD4-VPS13D |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-intron | ENST00000427716 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| 3UTR-intron | ENST00000427716 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| 3UTR-intron | ENST00000427716 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| 3UTR-intron | ENST00000427716 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| 3UTR-intron | ENST00000427716 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| 3UTR-intron | ENST00000427716 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| 5CDS-3UTR | ENST00000427716 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000427716 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000472289 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000472289 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000525053 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000525053 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000531134 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000531134 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000534526 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000534526 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000546442 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-3UTR | ENST00000546442 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000427716 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000427716 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000472289 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000472289 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000525053 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000525053 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000531134 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000531134 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000534526 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000534526 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000546442 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5CDS-intron | ENST00000546442 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5UTR-3CDS | ENST00000266482 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5UTR-3CDS | ENST00000266482 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5UTR-3UTR | ENST00000266482 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5UTR-3UTR | ENST00000266482 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5UTR-intron | ENST00000266482 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| 5UTR-intron | ENST00000266482 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| Frame-shift | ENST00000472289 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| Frame-shift | ENST00000472289 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000427716 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000427716 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000525053 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000525053 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000531134 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000531134 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000534526 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000534526 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000546442 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| In-frame | ENST00000546442 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3CDS | ENST00000381025 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3CDS | ENST00000381025 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3CDS | ENST00000473513 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3CDS | ENST00000473513 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3UTR | ENST00000381025 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3UTR | ENST00000381025 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3UTR | ENST00000473513 | ENST00000496628 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-3UTR | ENST00000473513 | ENST00000543766 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-intron | ENST00000266482 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000266482 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000266482 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000266482 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000266482 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000266482 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000381025 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000381025 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000381025 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-intron | ENST00000381025 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000381025 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000381025 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-intron | ENST00000381025 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000381025 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000472289 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000472289 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000472289 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000472289 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000472289 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000472289 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000473513 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000473513 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000473513 | ENST00000471923 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-intron | ENST00000473513 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000473513 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000473513 | ENST00000543710 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + |
| intron-intron | ENST00000473513 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000473513 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000525053 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000525053 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000525053 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000525053 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000525053 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000525053 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000531134 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000531134 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000531134 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000531134 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000531134 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000531134 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000534526 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000534526 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000534526 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000534526 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000534526 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000534526 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000546442 | ENST00000356315 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000546442 | ENST00000358136 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000546442 | ENST00000471923 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000546442 | ENST00000496628 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000546442 | ENST00000543710 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| intron-intron | ENST00000546442 | ENST00000543766 | FGD4 | chr12 | 32798659 | - | VPS13D | chr1 | 12481908 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000534526 | FGD4 | chr12 | 32735401 | + | ENST00000358136 | VPS13D | chr1 | 12516054 | + | 5131 | 1276 | 178 | 2109 | 643 |
| ENST00000534526 | FGD4 | chr12 | 32735401 | + | ENST00000356315 | VPS13D | chr1 | 12516054 | + | 5131 | 1276 | 178 | 2109 | 643 |
| ENST00000531134 | FGD4 | chr12 | 32735401 | + | ENST00000358136 | VPS13D | chr1 | 12516054 | + | 4872 | 1017 | 162 | 1850 | 562 |
| ENST00000531134 | FGD4 | chr12 | 32735401 | + | ENST00000356315 | VPS13D | chr1 | 12516054 | + | 4872 | 1017 | 162 | 1850 | 562 |
| ENST00000427716 | FGD4 | chr12 | 32735401 | + | ENST00000358136 | VPS13D | chr1 | 12516054 | + | 4879 | 1024 | 241 | 1857 | 538 |
| ENST00000427716 | FGD4 | chr12 | 32735401 | + | ENST00000356315 | VPS13D | chr1 | 12516054 | + | 4879 | 1024 | 241 | 1857 | 538 |
| ENST00000546442 | FGD4 | chr12 | 32735401 | + | ENST00000358136 | VPS13D | chr1 | 12516054 | + | 4671 | 816 | 330 | 1649 | 439 |
| ENST00000546442 | FGD4 | chr12 | 32735401 | + | ENST00000356315 | VPS13D | chr1 | 12516054 | + | 4671 | 816 | 330 | 1649 | 439 |
| ENST00000525053 | FGD4 | chr12 | 32735401 | + | ENST00000358136 | VPS13D | chr1 | 12516054 | + | 4875 | 1020 | 84 | 1853 | 589 |
| ENST00000525053 | FGD4 | chr12 | 32735401 | + | ENST00000356315 | VPS13D | chr1 | 12516054 | + | 4875 | 1020 | 84 | 1853 | 589 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000534526 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.001083777 | 0.99891627 |
| ENST00000534526 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.001083777 | 0.99891627 |
| ENST00000531134 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000797646 | 0.99920243 |
| ENST00000531134 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000797646 | 0.99920243 |
| ENST00000427716 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000633828 | 0.9993662 |
| ENST00000427716 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000633828 | 0.9993662 |
| ENST00000546442 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000790699 | 0.9992093 |
| ENST00000546442 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000790699 | 0.9992093 |
| ENST00000525053 | ENST00000358136 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000237387 | 0.9997626 |
| ENST00000525053 | ENST00000356315 | FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516054 | + | 0.000237387 | 0.9997626 |
Top |
Fusion Genomic Features for FGD4-VPS13D |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516053 | + | 0.000271069 | 0.99972886 |
| FGD4 | chr12 | 32735401 | + | VPS13D | chr1 | 12516053 | + | 0.000271069 | 0.99972886 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for FGD4-VPS13D |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:32735401/chr1:12516054) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FGD4 | . |
| FUNCTION: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8 (By similarity). {ECO:0000250, ECO:0000269|PubMed:15133042}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000427716 | + | 4 | 17 | 1_150 | 200 | 767.0 | Region | Actin filament-binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000381025 | + | 1 | 9 | 206_393 | 0 | 281.0 | Domain | DH |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000381025 | + | 1 | 9 | 422_521 | 0 | 281.0 | Domain | PH 1 |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000381025 | + | 1 | 9 | 643_740 | 0 | 281.0 | Domain | PH 2 |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000427716 | + | 4 | 17 | 206_393 | 200 | 767.0 | Domain | DH |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000427716 | + | 4 | 17 | 422_521 | 200 | 767.0 | Domain | PH 1 |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000427716 | + | 4 | 17 | 643_740 | 200 | 767.0 | Domain | PH 2 |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000381025 | + | 1 | 9 | 1_150 | 0 | 281.0 | Region | Actin filament-binding |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000381025 | + | 1 | 9 | 559_619 | 0 | 281.0 | Zinc finger | FYVE-type |
| Hgene | FGD4 | chr12:32735401 | chr1:12516054 | ENST00000427716 | + | 4 | 17 | 559_619 | 200 | 767.0 | Zinc finger | FYVE-type |
| Tgene | VPS13D | chr12:32735401 | chr1:12516054 | ENST00000356315 | 63 | 69 | 2633_2676 | 4086 | 4364.0 | Domain | UBA |
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Fusion Gene Sequence for FGD4-VPS13D |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >30173_30173_1_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000427716_VPS13D_chr1_12516054_ENST00000356315_length(transcript)=4879nt_BP=1024nt ATTATCCTTGCTGGGCTGGGAAGTGGGGAAAGCAGGGGAGCCTGTGCTGGGTGAGATTATCTGCAATGGACCGGGTTAATGGGAGGCTTG CTTTGGCTCGCTGGAAGAACAAATGAAGGGAGTTTTACTTCAACCATTTGTGACTTCTGGCCAAGAGGAATAAATTCAGCTTTTATAAGG CAGCAGTACCTGTCCAAAGATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGA GGCTCAGGGAATAAATGGGAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAA TTCACCTTCGTCCAATATACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGC TTCTTGTGTCTCAAAAGAAAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTT GAAGAAAGAGTCTGCTGTGAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCA GCACTTGCCACAGAGGCAGGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCA GATGGAATGTGAGGAGGAGAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAA TGGAGAAAGAGATGAAACTGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCC AGGCATAGGCCCAGTGCTCCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGA ACTGGAGCAGCTGGACCAGCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTC AGAGCGGGAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGG ACTGACCAGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGT TGGCACTGTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCC CAGGACTCAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGG ACAGGAGCAGCTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTC CTCCAAAGCTGTTTACTTCCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTG CCTTGTCTCCAAAGACCATGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTC CCACCAGAAGCCCATGGTCCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGA ACAGCAGCTTATGTTAAGACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACAC AGCGCAGACCCACCAGGAGGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAAT GAGGGAAAGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAAT TTTTAAAGGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATAT ATGTACAACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATA AAGTTATATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGT TACGTCTTAGTTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGG CTGTCCAGTTGGGCTGTGAGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAA TTTCTCACCCCCATTTTACAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCA AACTTAGGGGGAAACCTGTGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAA ACATTGGTAAACTCTGTTGATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCT GCCTGGGCAGCAACAACCAAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGG GGACACAGGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGT AAGTTTTTCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCT GGGTCTTGTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCAC CTTGTGATTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATC AGTGGATGCGTGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTC CTCTCCCACTTCCCCTCTGTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAG GGAGCTTTAGCACAAGTAGCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGT GGATTGCAGAATGGAAACTTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGC ACTCACGCACTGCACAAGATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCA CCCCCACAGGTTTGGCTTGTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTG ATTGTATGCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGA AAATCTGCTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGG AGGAATCCAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGC ACAACCAAGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGAT GGGAGGGCCAACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATT TGACATCCCCTCCTGGTTCTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTT TGTAAACTGATATTCAGCCAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTC TGAGGAAAGTAAAATAAATGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGAC CCGTGTCACTCCCTGGCTGTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTA CACAGTGGAAAACAGACAAGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTC CAGGGCCACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTA TGTAAACACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAAT >30173_30173_1_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000427716_VPS13D_chr1_12516054_ENST00000356315_length(amino acids)=538AA_BP=261 MVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIKPASASCVSKEKPSKVSDLISRFEG GSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQAS EPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKFAGTLSDGL GKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQA VRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFL -------------------------------------------------------------- >30173_30173_2_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000427716_VPS13D_chr1_12516054_ENST00000358136_length(transcript)=4879nt_BP=1024nt ATTATCCTTGCTGGGCTGGGAAGTGGGGAAAGCAGGGGAGCCTGTGCTGGGTGAGATTATCTGCAATGGACCGGGTTAATGGGAGGCTTG CTTTGGCTCGCTGGAAGAACAAATGAAGGGAGTTTTACTTCAACCATTTGTGACTTCTGGCCAAGAGGAATAAATTCAGCTTTTATAAGG CAGCAGTACCTGTCCAAAGATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGA GGCTCAGGGAATAAATGGGAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAA TTCACCTTCGTCCAATATACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGC TTCTTGTGTCTCAAAAGAAAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTT GAAGAAAGAGTCTGCTGTGAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCA GCACTTGCCACAGAGGCAGGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCA GATGGAATGTGAGGAGGAGAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAA TGGAGAAAGAGATGAAACTGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCC AGGCATAGGCCCAGTGCTCCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGA ACTGGAGCAGCTGGACCAGCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTC AGAGCGGGAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGG ACTGACCAGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGT TGGCACTGTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCC CAGGACTCAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGG ACAGGAGCAGCTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTC CTCCAAAGCTGTTTACTTCCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTG CCTTGTCTCCAAAGACCATGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTC CCACCAGAAGCCCATGGTCCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGA ACAGCAGCTTATGTTAAGACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACAC AGCGCAGACCCACCAGGAGGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAAT GAGGGAAAGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAAT TTTTAAAGGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATAT ATGTACAACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATA AAGTTATATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGT TACGTCTTAGTTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGG CTGTCCAGTTGGGCTGTGAGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAA TTTCTCACCCCCATTTTACAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCA AACTTAGGGGGAAACCTGTGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAA ACATTGGTAAACTCTGTTGATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCT GCCTGGGCAGCAACAACCAAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGG GGACACAGGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGT AAGTTTTTCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCT GGGTCTTGTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCAC CTTGTGATTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATC AGTGGATGCGTGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTC CTCTCCCACTTCCCCTCTGTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAG GGAGCTTTAGCACAAGTAGCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGT GGATTGCAGAATGGAAACTTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGC ACTCACGCACTGCACAAGATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCA CCCCCACAGGTTTGGCTTGTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTG ATTGTATGCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGA AAATCTGCTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGG AGGAATCCAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGC ACAACCAAGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGAT GGGAGGGCCAACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATT TGACATCCCCTCCTGGTTCTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTT TGTAAACTGATATTCAGCCAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTC TGAGGAAAGTAAAATAAATGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGAC CCGTGTCACTCCCTGGCTGTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTA CACAGTGGAAAACAGACAAGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTC CAGGGCCACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTA TGTAAACACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAAT >30173_30173_2_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000427716_VPS13D_chr1_12516054_ENST00000358136_length(amino acids)=538AA_BP=261 MVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIKPASASCVSKEKPSKVSDLISRFEG GSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQAS EPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKFAGTLSDGL GKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQA VRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFL -------------------------------------------------------------- >30173_30173_3_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000525053_VPS13D_chr1_12516054_ENST00000356315_length(transcript)=4875nt_BP=1020nt AGTGCATTGGTCTGAGCTCCTGGCAGATCCTGTGTAATCTTCAGCCTCCCTGAAGCTTTACAGCCAGGAGTGAGATTTTATCACATGAAC TTTAAAAGAGTAAAGCCAAATATCTTTTTATTAAACCAGAGTAGATTAATTATCAGTATATGTGAAATCATGTCCACTGATCAAGGCAGC AGTACCTGTCCAAAGATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCT CAGGGAATAAATGGGAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAATTCA CCTTCGTCCAATATACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGCTTCT TGTGTCTCAAAAGAAAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTTGAAG AAAGAGTCTGCTGTGAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCAC TTGCCACAGAGGCAGGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATG GAATGTGAGGAGGAGAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGA GAAAGAGATGAAACTGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGC ATAGGCCCAGTGCTCCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTG GAGCAGCTGGACCAGCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAG CGGGAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTG ACCAGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGC ACTGTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGG ACTCAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAG GAGCAGCTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCC AAAGCTGTTTACTTCCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTT GTCTCCAAAGACCATGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCAC CAGAAGCCCATGGTCCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAG CAGCTTATGTTAAGACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCG CAGACCCACCAGGAGGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGG GAAAGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTT AAAGGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGT ACAACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGT TATATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACG TCTTAGTTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGT CCAGTTGGGCTGTGAGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTC TCACCCCCATTTTACAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACT TAGGGGGAAACCTGTGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACAT TGGTAAACTCTGTTGATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCT GGGCAGCAACAACCAAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGAC ACAGGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGT TTTTCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGT CTTGTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTG TGATTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTG GATGCGTGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCT CCCACTTCCCCTCTGTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAG CTTTAGCACAAGTAGCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGAT TGCAGAATGGAAACTTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTC ACGCACTGCACAAGATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCC CACAGGTTTGGCTTGTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTG TATGCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAAT CTGCTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGA ATCCAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAA CCAAGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGA GGGCCAACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGAC ATCCCCTCCTGGTTCTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTA AACTGATATTCAGCCAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAG GAAAGTAAAATAAATGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGT GTCACTCCCTGGCTGTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACA GTGGAAAACAGACAAGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGG GCCACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTA AACACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAATGCCT >30173_30173_3_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000525053_VPS13D_chr1_12516054_ENST00000356315_length(amino acids)=589AA_BP=312 MNFKRVKPNIFLLNQSRLIISICEIMSTDQGSSTCPKIALVPPCSTSSTTTLVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQ NSPSSNIHQTPRHKALPSAKPRMEEIKPASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLS QHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRT PGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIG GLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAE GQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGP -------------------------------------------------------------- >30173_30173_4_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000525053_VPS13D_chr1_12516054_ENST00000358136_length(transcript)=4875nt_BP=1020nt AGTGCATTGGTCTGAGCTCCTGGCAGATCCTGTGTAATCTTCAGCCTCCCTGAAGCTTTACAGCCAGGAGTGAGATTTTATCACATGAAC TTTAAAAGAGTAAAGCCAAATATCTTTTTATTAAACCAGAGTAGATTAATTATCAGTATATGTGAAATCATGTCCACTGATCAAGGCAGC AGTACCTGTCCAAAGATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCT CAGGGAATAAATGGGAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAATTCA CCTTCGTCCAATATACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGCTTCT TGTGTCTCAAAAGAAAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTTGAAG AAAGAGTCTGCTGTGAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCAC TTGCCACAGAGGCAGGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATG GAATGTGAGGAGGAGAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGA GAAAGAGATGAAACTGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGC ATAGGCCCAGTGCTCCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTG GAGCAGCTGGACCAGCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAG CGGGAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTG ACCAGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGC ACTGTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGG ACTCAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAG GAGCAGCTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCC AAAGCTGTTTACTTCCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTT GTCTCCAAAGACCATGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCAC CAGAAGCCCATGGTCCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAG CAGCTTATGTTAAGACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCG CAGACCCACCAGGAGGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGG GAAAGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTT AAAGGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGT ACAACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGT TATATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACG TCTTAGTTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGT CCAGTTGGGCTGTGAGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTC TCACCCCCATTTTACAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACT TAGGGGGAAACCTGTGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACAT TGGTAAACTCTGTTGATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCT GGGCAGCAACAACCAAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGAC ACAGGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGT TTTTCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGT CTTGTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTG TGATTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTG GATGCGTGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCT CCCACTTCCCCTCTGTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAG CTTTAGCACAAGTAGCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGAT TGCAGAATGGAAACTTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTC ACGCACTGCACAAGATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCC CACAGGTTTGGCTTGTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTG TATGCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAAT CTGCTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGA ATCCAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAA CCAAGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGA GGGCCAACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGAC ATCCCCTCCTGGTTCTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTA AACTGATATTCAGCCAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAG GAAAGTAAAATAAATGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGT GTCACTCCCTGGCTGTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACA GTGGAAAACAGACAAGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGG GCCACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTA AACACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAATGCCT >30173_30173_4_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000525053_VPS13D_chr1_12516054_ENST00000358136_length(amino acids)=589AA_BP=312 MNFKRVKPNIFLLNQSRLIISICEIMSTDQGSSTCPKIALVPPCSTSSTTTLVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQ NSPSSNIHQTPRHKALPSAKPRMEEIKPASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLS QHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRT PGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIG GLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAE GQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGP -------------------------------------------------------------- >30173_30173_5_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000531134_VPS13D_chr1_12516054_ENST00000356315_length(transcript)=4872nt_BP=1017nt AGTTAGTTCTTTATCATGTTGAACACTAGATGTGTATGTGTCTAGTGTCTAAATACAGAATGCCTATAGTTTCTACCAACAAATTATGGA TCCAAATCCTTGCTCCAGAAGCAGGAAATAGGTTAATCAGAAGATTGCTGGATGTTATGAAAAGAATCTTTTATGGGGGGCTGCAGCAGT ACCTGTCCAAAGATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCTCAG GGAATAAATGGGAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAATTCACCT TCGTCCAATATACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGCTTCTTGT GTCTCAAAAGAAAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTTGAAGAAA GAGTCTGCTGTGAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCACTTG CCACAGAGGCAGGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATGGAA TGTGAGGAGGAGAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGAGAA AGAGATGAAACTGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGCATA GGCCCAGTGCTCCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTGGAG CAGCTGGACCAGCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGG GAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTGACC AGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGCACT GTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGGACT CAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAGGAG CAGCTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCCAAA GCTGTTTACTTCCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTGTC TCCAAAGACCATGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAG AAGCCCATGGTCCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAG CTTATGTTAAGACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAG ACCCACCAGGAGGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAA AGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTTAAA GGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGTACA ACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGTTAT ATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACGTCT TAGTTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGTCCA GTTGGGCTGTGAGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCTCA CCCCCATTTTACAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAG GGGGAAACCTGTGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGG TAAACTCTGTTGATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGG CAGCAACAACCAAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACA GGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGTTTT TCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGTCTT GTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTGTGA TTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTGGAT GCGTGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCTCCC ACTTCCCCTCTGTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGCTT TAGCACAAGTAGCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGC AGAATGGAAACTTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACG CACTGCACAAGATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCAC AGGTTTGGCTTGTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTAT GCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAATCTG CTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGAATC CAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAACCA AGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGAGGG CCAACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGACATC CCCTCCTGGTTCTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAAAC TGATATTCAGCCAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAA AGTAAAATAAATGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTC ACTCCCTGGCTGTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTG GAAAACAGACAAGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCC ACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTAAAC ACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAATGCCTTGT >30173_30173_5_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000531134_VPS13D_chr1_12516054_ENST00000356315_length(amino acids)=562AA_BP=285 MGGCSSTCPKIALVPPCSTSSTTTLVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIK PASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMA AQNQMECEEEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGE SPLELEQLDQHHEMKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLG KGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYC VLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKS -------------------------------------------------------------- >30173_30173_6_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000531134_VPS13D_chr1_12516054_ENST00000358136_length(transcript)=4872nt_BP=1017nt AGTTAGTTCTTTATCATGTTGAACACTAGATGTGTATGTGTCTAGTGTCTAAATACAGAATGCCTATAGTTTCTACCAACAAATTATGGA TCCAAATCCTTGCTCCAGAAGCAGGAAATAGGTTAATCAGAAGATTGCTGGATGTTATGAAAAGAATCTTTTATGGGGGGCTGCAGCAGT ACCTGTCCAAAGATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCTCAG GGAATAAATGGGAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAATTCACCT TCGTCCAATATACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGCTTCTTGT GTCTCAAAAGAAAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTTGAAGAAA GAGTCTGCTGTGAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCACTTG CCACAGAGGCAGGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATGGAA TGTGAGGAGGAGAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGAGAA AGAGATGAAACTGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGCATA GGCCCAGTGCTCCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTGGAG CAGCTGGACCAGCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGG GAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTGACC AGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGCACT GTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGGACT CAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAGGAG CAGCTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCCAAA GCTGTTTACTTCCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTGTC TCCAAAGACCATGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAG AAGCCCATGGTCCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAG CTTATGTTAAGACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAG ACCCACCAGGAGGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAA AGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTTAAA GGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGTACA ACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGTTAT ATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACGTCT TAGTTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGTCCA GTTGGGCTGTGAGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCTCA CCCCCATTTTACAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAG GGGGAAACCTGTGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGG TAAACTCTGTTGATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGG CAGCAACAACCAAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACA GGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGTTTT TCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGTCTT GTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTGTGA TTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTGGAT GCGTGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCTCCC ACTTCCCCTCTGTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGCTT TAGCACAAGTAGCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGC AGAATGGAAACTTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACG CACTGCACAAGATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCAC AGGTTTGGCTTGTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTAT GCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAATCTG CTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGAATC CAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAACCA AGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGAGGG CCAACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGACATC CCCTCCTGGTTCTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAAAC TGATATTCAGCCAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAA AGTAAAATAAATGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTC ACTCCCTGGCTGTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTG GAAAACAGACAAGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCC ACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTAAAC ACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAATGCCTTGT >30173_30173_6_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000531134_VPS13D_chr1_12516054_ENST00000358136_length(amino acids)=562AA_BP=285 MGGCSSTCPKIALVPPCSTSSTTTLVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIK PASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMA AQNQMECEEEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGE SPLELEQLDQHHEMKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLG KGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYC VLISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKS -------------------------------------------------------------- >30173_30173_7_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000534526_VPS13D_chr1_12516054_ENST00000356315_length(transcript)=5131nt_BP=1276nt GGTAGCGGCTTTGAGTGAGTGCGGGAGCTGCAGATACCGAGACGCTGCGACTGCCGCAGGAGTCGCCGCAGCCAAACTCGCCGCGACGCC GGGAGGGAGCGTACCGGGAAGGAGAGGGAGAGGAGGCACTCGCTGAGGAGACGCCGCAGTAGAGGGCGCCCCCGGAGTCGCGCCGAACCT GGGCATGCAGGCGACGCCCCCCAGGGGCCGCTCGCGGCTGGACGGGAGCGGGAGGAGTCGGGGAGCGGCGGTCGAGCCCGGCAGGATGAG CGACGAGGGCGGCTCCAACTTCAGGCGGGTGGCGATCCGGCGGAAGTCCAACCCCTCCTACCTGCCGCCCGGGGTGCCCCGGCCCTGGAG CAGGCCCGCGTCGCACCTGGGACGTGTAGGGACCGCTGCCTTCAAGGGCCAGGTGCCCTCAGGAGCCACAGGCAGCAGTACCTGTCCAAA GATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCTCAGGGAATAAATGG GAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAATTCACCTTCGTCCAATAT ACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGCTTCTTGTGTCTCAAAAGA AAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTTGAAGAAAGAGTCTGCTGT GAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCACTTGCCACAGAGGCA GGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATGGAATGTGAGGAGGA GAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGAGAAAGAGATGAAAC TGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGCATAGGCCCAGTGCT CCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTGGAGCAGCTGGACCA GCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGGGAGTACATCAG GTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTGACCAGTGTTATAAC TTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGCACTGTAACCAAGCC AGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGGACTCAAGCACAGAG GGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAGGAGCAGCTCTTCAA ACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCCAAAGCTGTTTACTT CCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTGTCTCCAAAGACCA TGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAGAAGCCCATGGT CCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAGCTTATGTTAAG ACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAGACCCACCAGGA GGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAAAGTAAATCCTC ATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTTAAAGGTATTGGTTA AATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGTACAACAGTGTGTTT GTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGTTATATTGGATCTTC TATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACGTCTTAGTTTTGGAG ACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGTCCAGTTGGGCTGTG AGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCTCACCCCCATTTTA CAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAGGGGGAAACCTG TGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGGTAAACTCTGTT GATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGGCAGCAACAACC AAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACAGGATGGAAACC CCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGTTTTTCATGGAACCA AGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGTCTTGTTTTTGGTGT TTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTGTGATTTTTAAATTT TTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTGGATGCGTGGAAGGT TTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCTCCCACTTCCCCTCT GTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGCTTTAGCACAAGTA GCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGCAGAATGGAAAC TTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACGCACTGCACAAG ATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCACAGGTTTGGCTT GTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTATGCGTCAGTGAG CCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAATCTGCTTTGGGCCGC AGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGAATCCAGAGAAGTGT TCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAACCAAGCACTTTGAC ATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGAGGGCCAACTGCGAG CTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGACATCCCCTCCTGGTT CTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAAACTGATATTCAGC CAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAAAGTAAAATAAA TGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTCACTCCCTGGCT GTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTGGAAAACAGACA AGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCCACTTTGTTTGT AAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTAAACACTATTACAGT CACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAATGCCTTGTGGACTTCCCAA >30173_30173_7_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000534526_VPS13D_chr1_12516054_ENST00000356315_length(amino acids)=643AA_BP=366 MGMQATPPRGRSRLDGSGRSRGAAVEPGRMSDEGGSNFRRVAIRRKSNPSYLPPGVPRPWSRPASHLGRVGTAAFKGQVPSGATGSSTCP KIALVPPCSTSSTTTLVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIKPASASCVSK EKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEE EKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLD QHHEMKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTK PVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVY FLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLML -------------------------------------------------------------- >30173_30173_8_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000534526_VPS13D_chr1_12516054_ENST00000358136_length(transcript)=5131nt_BP=1276nt GGTAGCGGCTTTGAGTGAGTGCGGGAGCTGCAGATACCGAGACGCTGCGACTGCCGCAGGAGTCGCCGCAGCCAAACTCGCCGCGACGCC GGGAGGGAGCGTACCGGGAAGGAGAGGGAGAGGAGGCACTCGCTGAGGAGACGCCGCAGTAGAGGGCGCCCCCGGAGTCGCGCCGAACCT GGGCATGCAGGCGACGCCCCCCAGGGGCCGCTCGCGGCTGGACGGGAGCGGGAGGAGTCGGGGAGCGGCGGTCGAGCCCGGCAGGATGAG CGACGAGGGCGGCTCCAACTTCAGGCGGGTGGCGATCCGGCGGAAGTCCAACCCCTCCTACCTGCCGCCCGGGGTGCCCCGGCCCTGGAG CAGGCCCGCGTCGCACCTGGGACGTGTAGGGACCGCTGCCTTCAAGGGCCAGGTGCCCTCAGGAGCCACAGGCAGCAGTACCTGTCCAAA GATCGCTTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCTCAGGGAATAAATGG GAACAGGCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGTGCCTCCAAAGCCATTACACCTGCAGAATTCACCTTCGTCCAATAT ACACCAAACCCCCAGGCATAAAGCTTTACCTAGTGCAAAACCAAGGATGGAGGAAATTAAACCTGCCTCTGCTTCTTGTGTCTCAAAAGA AAAACCCAGTAAGGTATCAGATCTCATCAGTCGCTTTGAAGGAGGCAGCTCATTATCAAATTATAGTGATTTGAAGAAAGAGTCTGCTGT GAACCTAAATGCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCACTTGCCACAGAGGCA GGGAAATGATACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATGGAATGTGAGGAGGA GAAAGCTGCCACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGAGAAAGAGATGAAAC TGCCACAGCTCCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGCATAGGCCCAGTGCT CCCCCTAGAAGAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTGGAGCAGCTGGACCA GCACCATGAGATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGGGAGTACATCAG GTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTGACCAGTGTTATAAC TTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGCACTGTAACCAAGCC AGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGGACTCAAGCACAGAG GGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAGGAGCAGCTCTTCAA ACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCCAAAGCTGTTTACTT CCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTGTCTCCAAAGACCA TGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAGAAGCCCATGGT CCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAGCTTATGTTAAG ACTCAGCGAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAGACCCACCAGGA GGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAAAGTAAATCCTC ATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTTAAAGGTATTGGTTA AATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGTACAACAGTGTGTTT GTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGTTATATTGGATCTTC TATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACGTCTTAGTTTTGGAG ACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGTCCAGTTGGGCTGTG AGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCTCACCCCCATTTTA CAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAGGGGGAAACCTG TGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGGTAAACTCTGTT GATTGAGAAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGGCAGCAACAACC AAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACAGGATGGAAACC CCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGTTTTTCATGGAACCA AGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGTCTTGTTTTTGGTGT TTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTGTGATTTTTAAATTT TTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTGGATGCGTGGAAGGT TTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCTCCCACTTCCCCTCT GTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGCTTTAGCACAAGTA GCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGCAGAATGGAAAC TTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACGCACTGCACAAG ATGGCAGCAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCACAGGTTTGGCTT GTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTATGCGTCAGTGAG CCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAATCTGCTTTGGGCCGC AGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGAATCCAGAGAAGTGT TCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAACCAAGCACTTTGAC ATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGAGGGCCAACTGCGAG CTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGACATCCCCTCCTGGTT CTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAAACTGATATTCAGC CAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAAAGTAAAATAAA TGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTCACTCCCTGGCT GTCGCTGCTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTGGAAAACAGACA AGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCCACTTTGTTTGT AAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTAAACACTATTACAGT CACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGTGGAATAAAATGCCTTGTGGACTTCCCAA >30173_30173_8_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000534526_VPS13D_chr1_12516054_ENST00000358136_length(amino acids)=643AA_BP=366 MGMQATPPRGRSRLDGSGRSRGAAVEPGRMSDEGGSNFRRVAIRRKSNPSYLPPGVPRPWSRPASHLGRVGTAAFKGQVPSGATGSSTCP KIALVPPCSTSSTTTLVGENVSEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIKPASASCVSK EKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEE EKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLD QHHEMKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTK PVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVY FLKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVLAVKLSQEINYAKSLYYEQQLML -------------------------------------------------------------- >30173_30173_9_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000546442_VPS13D_chr1_12516054_ENST00000356315_length(transcript)=4671nt_BP=816nt GGGGAAAGCAGGGGAGCCTGTGCTGGGTGAGATTATCTGCAATGGACCGGGTTAATGGGAGGCTTGCTTTGGCTCGCTGGAAGAACAAAT GAAGGGAGTTTTACTTCAACCATTTGTGACTTCTGGCCAAGAGGAATAAATTCAGCTTTTATAAGGCAGCAGTACCTGTCCAAAGATCGC TTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCTCAGGGAATAAATGGGAACAG GCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGCTCATTATCAAATTATAGTGATTTGAAGAAAGAGTCTGCTGTGAACCTAAAT GCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCACTTGCCACAGAGGCAGGGAAATGAT ACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATGGAATGTGAGGAGGAGAAAGCTGCC ACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGAGAAAGAGATGAAACTGCCACAGCT CCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGCATAGGCCCAGTGCTCCCCCTAGAA GAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTGGAGCAGCTGGACCAGCACCATGAG ATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGGGAGTACATCAGGTACCATGCA GCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTGACCAGTGTTATAACTTCGACAGTG GAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGCACTGTAACCAAGCCAGTGGCAGGC GCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGGACTCAAGCACAGAGGGTTCGGAAA CCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAGGAGCAGCTCTTCAAACTCACAGAC AACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCCAAAGCTGTTTACTTCCTGAAAAGT GGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTGTCTCCAAAGACCATGGGAAGGTG TATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAGAAGCCCATGGTCCATGTGAAA TCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAGCTTATGTTAAGACTCAGCGAA AACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAGACCCACCAGGAGGAAAGAGGC CCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAAAGTAAATCCTCATGAGGAAAA GTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTTAAAGGTATTGGTTAAATAACGTTT AAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGTACAACAGTGTGTTTGTAAATATAT AGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGTTATATTGGATCTTCTATTGCACTA ATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACGTCTTAGTTTTGGAGACTAAAGTAT TCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGTCCAGTTGGGCTGTGAGCTGTGGCA CCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCTCACCCCCATTTTACAAAGAGTGC TTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAGGGGGAAACCTGTGCTCCATTA CCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGGTAAACTCTGTTGATTGAGAAG GAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGGCAGCAACAACCAAGAACAAAG CCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACAGGATGGAAACCCCAGGATGAG AAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGTTTTTCATGGAACCAAGATTTGACA AAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGTCTTGTTTTTGGTGTTTCGCTTTTC TGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTGTGATTTTTAAATTTTTATTTTAAT AAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTGGATGCGTGGAAGGTTTTGGTGTTT ATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCTCCCACTTCCCCTCTGTGTCTGTGT CTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGCTTTAGCACAAGTAGCTACATAGT GTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGCAGAATGGAAACTTGGCTTTTG CGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACGCACTGCACAAGATGGCAGCAG GATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCACAGGTTTGGCTTGTGGTTTTTG TCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTATGCGTCAGTGAGCCTTCTATCA CCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAATCTGCTTTGGGCCGCAGCAGTGCTG GGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGAATCCAGAGAAGTGTTCAGATGCCC CCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAACCAAGCACTTTGACATTTGCACCT TAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGAGGGCCAACTGCGAGCTGCTCCACT TCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGACATCCCCTCCTGGTTCTCACCAGGA AAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAAACTGATATTCAGCCAGCAATGCC TAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAAAGTAAAATAAATGGAATAAGA GTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTCACTCCCTGGCTGTCGCTGCTT CTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTGGAAAACAGACAAGCGGCCCCT TCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCCACTTTGTTTGTAAGTATGATC TGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTAAACACTATTACAGTCACCAGTGTG >30173_30173_9_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000546442_VPS13D_chr1_12516054_ENST00000356315_length(amino acids)=439AA_BP=162 MKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLDTHIV NGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKFAGTLSDGLGKTMDNRHQ SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSG PRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYH -------------------------------------------------------------- >30173_30173_10_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000546442_VPS13D_chr1_12516054_ENST00000358136_length(transcript)=4671nt_BP=816nt GGGGAAAGCAGGGGAGCCTGTGCTGGGTGAGATTATCTGCAATGGACCGGGTTAATGGGAGGCTTGCTTTGGCTCGCTGGAAGAACAAAT GAAGGGAGTTTTACTTCAACCATTTGTGACTTCTGGCCAAGAGGAATAAATTCAGCTTTTATAAGGCAGCAGTACCTGTCCAAAGATCGC TTTAGTTCCACCTTGCTCCACAAGCAGCACAACCACACTGGTTGGTGAGAATGTATCTGAAGAAGAGGCTCAGGGAATAAATGGGAACAG GCCAGCAAAACACTCAGCTGCAAGTCCAAAGCCACAAGCTCATTATCAAATTATAGTGATTTGAAGAAAGAGTCTGCTGTGAACCTAAAT GCTCCTAGAACCCCAGGAAGGCATGGATTGACAACCACACCTCAACAAAAACTCCTCTCCCAGCACTTGCCACAGAGGCAGGGAAATGAT ACAGATAAGACTCAGGGTGCACAGACTTGTGTGGCCAACGGTGTAATGGCAGCACAAAACCAGATGGAATGTGAGGAGGAGAAAGCTGCC ACTCTTAGCTCAGATACTTCTATTCAAGCTTCTGAACCCTTGCTTGATACGCACATAGTGAATGGAGAAAGAGATGAAACTGCCACAGCT CCTGCATCACCCACAACAGACAGCTGTGATGGAAATGCTTCTGACAGTAGCTACAGGACTCCAGGCATAGGCCCAGTGCTCCCCCTAGAA GAAAGAGGGGCAGAAACAGAAACCAAGGTACAAGAGAGGGAAAATGGGGAAAGCCCTCTGGAACTGGAGCAGCTGGACCAGCACCATGAG ATGAAGTTTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGGGAGTACATCAGGTACCATGCA GCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTGACCAGTGTTATAACTTCGACAGTG GAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGCACTGTAACCAAGCCAGTGGCAGGC GCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCCCAGGACTCAAGCACAGAGGGTTCGGAAA CCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAGGAGCAGCTCTTCAAACTCACAGAC AACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCCAAAGCTGTTTACTTCCTGAAAAGT GGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTGTCTCCAAAGACCATGGGAAGGTG TATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAGAAGCCCATGGTCCATGTGAAA TCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAGCTTATGTTAAGACTCAGCGAA AACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAGACCCACCAGGAGGAAAGAGGC CCAGCTCTCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAAAGTAAATCCTCATGAGGAAAA GTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTTAAAGGTATTGGTTAAATAACGTTT AAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGTACAACAGTGTGTTTGTAAATATAT AGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATAAAGTTATATTGGATCTTCTATTGCACTA ATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACGTCTTAGTTTTGGAGACTAAAGTAT TCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGTCCAGTTGGGCTGTGAGCTGTGGCA CCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCTCACCCCCATTTTACAAAGAGTGC TTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAGGGGGAAACCTGTGCTCCATTA CCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGGTAAACTCTGTTGATTGAGAAG GAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGGCAGCAACAACCAAGAACAAAG CCCCGGGACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACAGGATGGAAACCCCAGGATGAG AAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGTTTTTCATGGAACCAAGATTTGACA AAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGTCTTGTTTTTGGTGTTTCGCTTTTC TGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCACCTTGTGATTTTTAAATTTTTATTTTAAT AAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTGGATGCGTGGAAGGTTTTGGTGTTT ATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCTCCCACTTCCCCTCTGTGTCTGTGT CTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGCTTTAGCACAAGTAGCTACATAGT GTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGCAGAATGGAAACTTGGCTTTTG CGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACGCACTGCACAAGATGGCAGCAG GATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCACAGGTTTGGCTTGTGGTTTTTG TCATCAGTAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTATGCGTCAGTGAGCCTTCTATCA CCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAATCTGCTTTGGGCCGCAGCAGTGCTG GGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGAATCCAGAGAAGTGTTCAGATGCCC CCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGCACAACCAAGCACTTTGACATTTGCACCT TAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGAGGGCCAACTGCGAGCTGCTCCACT TCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGACATCCCCTCCTGGTTCTCACCAGGA AAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAAACTGATATTCAGCCAGCAATGCC TAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAAAGTAAAATAAATGGAATAAGA GTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTCACTCCCTGGCTGTCGCTGCTT CTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTGGAAAACAGACAAGCGGCCCCT TCCCCAAATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCCACTTTGTTTGTAAGTATGATC TGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTAAACACTATTACAGTCACCAGTGTG >30173_30173_10_FGD4-VPS13D_FGD4_chr12_32735401_ENST00000546442_VPS13D_chr1_12516054_ENST00000358136_length(amino acids)=439AA_BP=162 MKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLDTHIV NGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKFAGTLSDGLGKTMDNRHQ SEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSG PRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLKSGDYVDREAIFLEVKYDDLYH -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for FGD4-VPS13D |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for FGD4-VPS13D |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for FGD4-VPS13D |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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