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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FGF13-MST4 (FusionGDB2 ID:30214)

Fusion Gene Summary for FGF13-MST4

check button Fusion gene summary
Fusion gene informationFusion gene name: FGF13-MST4
Fusion gene ID: 30214
HgeneTgene
Gene symbol

FGF13

MST4

Gene ID

2258

51765

Gene namefibroblast growth factor 13serine/threonine kinase 26
SynonymsFGF-13|FGF2|FHF-2|FHF2|LINC00889MASK|MST4
Cytomap

Xq26.3-q27.1

Xq26.2

Type of geneprotein-codingprotein-coding
Descriptionfibroblast growth factor 13fibroblast growth factor homologous factor 2serine/threonine-protein kinase 26Mst3 and SOK1-related kinaseSTE20-like kinase 4STE20-like kinase MST4mammalian Ste20-like protein kinase 4mammalian sterile 20-like 4serine/threonine protein kinase 26serine/threonine protein kinase MST4serine/thr
Modification date2020031320200322
UniProtAcc

Q92913

.
Ensembl transtripts involved in fusion geneENST00000370603, ENST00000541469, 
ENST00000305414, ENST00000315930, 
ENST00000441825, 		ENST00000394335, 
ENST00000496850, ENST00000354719, 
ENST00000394334, ENST00000481105, 
Fusion gene scores* DoF score10 X 5 X 4=2004 X 3 X 3=36
# samples 94
** MAII scorelog2(9/200*10)=-1.15200309344505
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: FGF13 [Title/Abstract] AND MST4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFGF13(138286221)-MST4(131188659), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFGF13

GO:0000165

MAPK cascade

12244047

TgeneMST4

GO:0006468

protein phosphorylation

11641781

TgeneMST4

GO:0030033

microvillus assembly

22797597

TgeneMST4

GO:0042542

response to hydrogen peroxide

22291017

TgeneMST4

GO:0042981

regulation of apoptotic process

11741893


check buttonFusion gene breakpoints across FGF13 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MST4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-1592-01AFGF13chrX

138286221

-MST4chrX

131188659

+


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Fusion Gene ORF analysis for FGF13-MST4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000370603ENST00000394335FGF13chrX

138286221

-MST4chrX

131188659

+
5CDS-intronENST00000370603ENST00000496850FGF13chrX

138286221

-MST4chrX

131188659

+
5CDS-intronENST00000541469ENST00000394335FGF13chrX

138286221

-MST4chrX

131188659

+
5CDS-intronENST00000541469ENST00000496850FGF13chrX

138286221

-MST4chrX

131188659

+
In-frameENST00000370603ENST00000354719FGF13chrX

138286221

-MST4chrX

131188659

+
In-frameENST00000370603ENST00000394334FGF13chrX

138286221

-MST4chrX

131188659

+
In-frameENST00000370603ENST00000481105FGF13chrX

138286221

-MST4chrX

131188659

+
In-frameENST00000541469ENST00000354719FGF13chrX

138286221

-MST4chrX

131188659

+
In-frameENST00000541469ENST00000394334FGF13chrX

138286221

-MST4chrX

131188659

+
In-frameENST00000541469ENST00000481105FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000305414ENST00000354719FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000305414ENST00000394334FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000305414ENST00000481105FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000315930ENST00000354719FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000315930ENST00000394334FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000315930ENST00000481105FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000441825ENST00000354719FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000441825ENST00000394334FGF13chrX

138286221

-MST4chrX

131188659

+
intron-3CDSENST00000441825ENST00000481105FGF13chrX

138286221

-MST4chrX

131188659

+
intron-intronENST00000305414ENST00000394335FGF13chrX

138286221

-MST4chrX

131188659

+
intron-intronENST00000305414ENST00000496850FGF13chrX

138286221

-MST4chrX

131188659

+
intron-intronENST00000315930ENST00000394335FGF13chrX

138286221

-MST4chrX

131188659

+
intron-intronENST00000315930ENST00000496850FGF13chrX

138286221

-MST4chrX

131188659

+
intron-intronENST00000441825ENST00000394335FGF13chrX

138286221

-MST4chrX

131188659

+
intron-intronENST00000441825ENST00000496850FGF13chrX

138286221

-MST4chrX

131188659

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000370603FGF13chrX138286221-ENST00000394334MST4chrX131188659+304249371257406
ENST00000370603FGF13chrX138286221-ENST00000481105MST4chrX131188659+162649371323428
ENST00000370603FGF13chrX138286221-ENST00000354719MST4chrX131188659+297049371185382
ENST00000541469FGF13chrX138286221-ENST00000394334MST4chrX131188659+304249371257406
ENST00000541469FGF13chrX138286221-ENST00000481105MST4chrX131188659+162649371323428
ENST00000541469FGF13chrX138286221-ENST00000354719MST4chrX131188659+297049371185382

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000370603ENST00000394334FGF13chrX138286221-MST4chrX131188659+0.0001651220.9998349
ENST00000370603ENST00000481105FGF13chrX138286221-MST4chrX131188659+0.0009830120.999017
ENST00000370603ENST00000354719FGF13chrX138286221-MST4chrX131188659+0.0001637580.9998362
ENST00000541469ENST00000394334FGF13chrX138286221-MST4chrX131188659+0.0001651220.9998349
ENST00000541469ENST00000481105FGF13chrX138286221-MST4chrX131188659+0.0009830120.999017
ENST00000541469ENST00000354719FGF13chrX138286221-MST4chrX131188659+0.0001637580.9998362

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Fusion Genomic Features for FGF13-MST4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FGF13chrX138286220-MST4chrX131188658+9.57E-050.9999043
FGF13chrX138286220-MST4chrX131188658+9.57E-050.9999043

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FGF13-MST4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:138286221/chrX:131188659)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FGF13

Q92913

.
FUNCTION: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). May regulate voltage-gated sodium channels transport and function (PubMed:15282281). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity). {ECO:0000250|UniProtKB:P70377, ECO:0000269|PubMed:15282281}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMST4chrX:138286221chrX:131188659ENST0000039433411224_27414417.0DomainProtein kinase
TgeneMST4chrX:138286221chrX:131188659ENST0000039433411230_3814417.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for FGF13-MST4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>30214_30214_1_FGF13-MST4_FGF13_chrX_138286221_ENST00000370603_MST4_chrX_131188659_ENST00000354719_length(transcript)=2970nt_BP=49nt
ATGAGTGGAAAGGTGACCAAGCCCAAAGAGGAGAAAGATGCTTCTAAGGAATAACATAGCTGATCCAGAAGAACTGTTCACAAAATTAGA
GCGCATTGGGAAAGGCTCATTTGGGGAAGTTTTCAAAGGAATTGATAACCGTACCCAGCAAGTCGTTGCTATTAAAATCATAGACCTTGA
GGAAGCCGAAGATGAAATAGAAGACATTCAGCAAGAAATAACTGTCTTGAGTCAATGTGACAGCTCATATGTAACAAAATACTATGGGTC
ATATTTAAAGGGGTCTAAATTATGGATAATAATGGAATACCTGGGCGGTGGTTCAGCACTGGATCTTCTTCGAGCTGGTCCATTTGATGA
GTTCCAGATTGCTACCATGCTAAAGGAAATTTTAAAAGGTCTGGACTATCTGCATTCAGAAAAGAAAATTCACCGAGACATAAAAGCTGC
CAATGTCTTGCTCTCAGAACAAGGAGATGTTAAACTTGCTGATTTTGGAGTTGCTGGTCAGCTGACAGATACACAGATTAAAAGAAATAC
CTTTGTGGGAACTCCATTTTGGATGGCTCCTGAAGTTATTCAACAGTCAGCTTATGACTCAAAAGCTGACATTTGGTCATTGGGAATTAC
TGCTATTGAACTAGCCAAGGGAGAGCCACCTAACTCCGATATGCATCCAATGAGAGTTCTGTTTCTTATTCCCAAAAACAATCCTCCAAC
TCTTGTTGGAGACTTTACTAAGTCTTTTAAGGAGTTTATTGATGCTTGCCTGAACAAAGATCCATCATTTCGTCCTACAGCAAAAGAACT
TCTGAAACACAAATTCATTGTAAAAAATTCAAAGAAGACTTCTTATCTGACTGAACTGATAGATCGTTTTAAGAGATGGAAGGCAGAAGG
ACACAGTGATGATGAATCTGATTCCGAGGGCTCTGATTCGGAATCTACCAGCAGGGAAAACAATACTCATCCTGAATGGAGCTTTACCAC
CGTACGAAAGAAGCCTGATCCAAAGAAAGTACAGAATGGGGCACAGGACGAGAATAACGCTAGCAGGAATCAGGCGATTGAAGAACTCGA
GAAAAGTATTGCTGTGGCTGAAGCCGCCTGTCCCGGCATCACAGATAAAATGGTGAAGAAACTAATTGAAAAATTTCAAAAGTGTTCAGC
AGACGAATCCCCCTAAGAAACTTATTATTGGCTTCTGTTTCATATGGACCCAGAGAGCCCCACCAAACCTACGTCAAGATTAACAATGCT
TAACCCATGAGCTCCATGTGCCTTTTGGATCTTTGCAACACTGAAGATTTGGAAGAAGCTATTAAACTATTTTGTGATGGCGTTTATCAT
TTTATATTTTGAAAGGATTATTTTGTAAGGAATAACTTTTAATACTATAGTTTCACCTGTATTCTAGTAAATGTTGAGACACCGTTTTGC
TTTTAAGTATCCCTATTTCTTAAGTTACGAGGATGAATACCTTTCACATTTTGATCTTTAGTTGACTCTACAGTCATGAAACATACAGGT
CTTTCAAAGTCATTCTCAATATTCAGCTTTTGTAAATTATCAAGCTTCAAAAAGCTTTTTTTTTTAAAAAAAAACATGCATATTCTAAAA
ATGACTATTGGTGGGGAGGTGTAAATAAGTCATACCTTCTTAAAACAGAAAATTTAAGTAAAGTCTTTTAAATGAAACCTGTAAAAGTAT
TGACTCTTCTACCAAGTTGGTATGATATTCCAGGCAGCTCAATGATTATCACATTTGAGACCCTGTGTTTGAAGCATTTACAGGCAATGT
ACAGCAACAGAGGTACCTCTTGGTGTATAGTATTTACATTCTCTTTTAGGTAGAAGAGGCAATTTTACCCTTATTTCACATGGTTAGAAA
TTTAAAGCAAGATCATTTACCCAAGGATAGGTGTTTGGTAATGTTGAAGGAGTTAGTCTGGCTTCATGTTTTACATCTTCAACTAAAATC
CCATACTATCTGCTTGGATTTGGAGAGCCAAAAAATAAAGCTGATTGTCATGTGATTAAATATCTGATCAACAGGTATGAATATAACTTA
AATCAGCATATTTTTGCCATGGTAATAAATTGTCCTATAAACTATTTATATATTTTTGTTCTTCATAATTATCACTAATAAGCATCAGTT
TGTTGTTTTTAAAAGGATATTTAAGTGAGCATTTTCTAGTTCATATGAAAATAACCATAGTACAGGATGATTTCTGTCCACACAAAGGTT
AAATTAGATTGCACAGTTAATTTTCACTTATATTTATGGTACTATTATGTGGGTGATGCCTTTTTCTTTTAAGCCCAGTACATATATTAT
GCCTGCCTAAGTTCTGAACTGGGGCTGTATTTCAGTAGTTGTAGAATTATTGATATTTAGTTTTGATAGCTAATGTTTAATTGTTTGGAT
CTGCACAGTTTGGTTTTTGCACAAAAGTCATTTAAAAAAATCTGAGTAATTGTCAAATATTAAAAGAAAGATATTCTTCCTGTAAGGAAT
ACAGTTTTTAGTCAAAGTGGCCATTACATCCTCTTTTTAATTTACATAATACAGATACTTGAGAAAGTTGTTGTGGTGTTGTATGCCAAG
AAAATTCTTTTTATTGGTGCCTATATTGTAACAATTATTTTTAATGCATTGTATTTTGAAGTAACGGTTCAGTTAAATTTTTCACCTGCT
GTGTAACTGAAACACAATTACAGTTTATAATCATCTGTAGAAGTCTGGAGATAATTTTGCAACTCATGTTATGGGTTAAATGAATATTTT
TGTAAAAGTAAAAGCAACAAATTTATAAATTGATTATTTGAAACTTTACAACACAATTGCATCCCAAATACAAATTGTATTGCTTATTCA
TTATAGCTATTCGTCCTGTAATCTGTTTCTAGGTGAAGCATACTCCAGTGTTTTAGGGGTTTTGAAAATAAATATTTAAATTTCACAGTC

>30214_30214_1_FGF13-MST4_FGF13_chrX_138286221_ENST00000370603_MST4_chrX_131188659_ENST00000354719_length(amino acids)=382AA_BP=2
MLLRNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIME
YLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV
IQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKK
TSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAQDENNASRNQAIEELEKSIAVAEAACPG

--------------------------------------------------------------
>30214_30214_2_FGF13-MST4_FGF13_chrX_138286221_ENST00000370603_MST4_chrX_131188659_ENST00000394334_length(transcript)=3042nt_BP=49nt
ATGAGTGGAAAGGTGACCAAGCCCAAAGAGGAGAAAGATGCTTCTAAGGAATAACATAGCTGATCCAGAAGAACTGTTCACAAAATTAGA
GCGCATTGGGAAAGGCTCATTTGGGGAAGTTTTCAAAGGAATTGATAACCGTACCCAGCAAGTCGTTGCTATTAAAATCATAGACCTTGA
GGAAGCCGAAGATGAAATAGAAGACATTCAGCAAGAAATAACTGTCTTGAGTCAATGTGACAGCTCATATGTAACAAAATACTATGGGTC
ATATTTAAAGGGGTCTAAATTATGGATAATAATGGAATACCTGGGCGGTGGTTCAGCACTGGATCTTCTTCGAGCTGGTCCATTTGATGA
GTTCCAGATTGCTACCATGCTAAAGGAAATTTTAAAAGGTCTGGACTATCTGCATTCAGAAAAGAAAATTCACCGAGACATAAAAGCTGC
CAATGTCTTGCTCTCAGAACAAGGAGATGTTAAACTTGCTGATTTTGGAGTTGCTGGTCAGCTGACAGATACACAGATTAAAAGAAATAC
CTTTGTGGGAACTCCATTTTGGATGGCTCCTGAAGTTATTCAACAGTCAGCTTATGACTCAAAAGCTGACATTTGGTCATTGGGAATTAC
TGCTATTGAACTAGCCAAGGGAGAGCCACCTAACTCCGATATGCATCCAATGAGAGTTCTGTTTCTTATTCCCAAAAACAATCCTCCAAC
TCTTGTTGGAGACTTTACTAAGTCTTTTAAGGAGTTTATTGATGCTTGCCTGAACAAAGATCCATCATTTCGTCCTACAGCAAAAGAACT
TCTGAAACACAAATTCATTGTAAAAAATTCAAAGAAGACTTCTTATCTGACTGAACTGATAGATCGTTTTAAGAGATGGAAGGCAGAAGG
ACACAGTGATGATGAATCTGATTCCGAGGGCTCTGATTCGGAATCTACCAGCAGGGAAAACAATACTCATCCTGAATGGAGCTTTACCAC
CGTACGAAAGAAGCCTGATCCAAAGAAAGTACAGAATGGGGCAGAGCAAGATCTTGTGCAAACCCTGAGTTGTTTGTCTATGATAATCAC
ACCTGCATTTGCTGAACTTAAACAGCAGGACGAGAATAACGCTAGCAGGAATCAGGCGATTGAAGAACTCGAGAAAAGTATTGCTGTGGC
TGAAGCCGCCTGTCCCGGCATCACAGATAAAATGGTGAAGAAACTAATTGAAAAATTTCAAAAGTGTTCAGCAGACGAATCCCCCTAAGA
AACTTATTATTGGCTTCTGTTTCATATGGACCCAGAGAGCCCCACCAAACCTACGTCAAGATTAACAATGCTTAACCCATGAGCTCCATG
TGCCTTTTGGATCTTTGCAACACTGAAGATTTGGAAGAAGCTATTAAACTATTTTGTGATGGCGTTTATCATTTTATATTTTGAAAGGAT
TATTTTGTAAGGAATAACTTTTAATACTATAGTTTCACCTGTATTCTAGTAAATGTTGAGACACCGTTTTGCTTTTAAGTATCCCTATTT
CTTAAGTTACGAGGATGAATACCTTTCACATTTTGATCTTTAGTTGACTCTACAGTCATGAAACATACAGGTCTTTCAAAGTCATTCTCA
ATATTCAGCTTTTGTAAATTATCAAGCTTCAAAAAGCTTTTTTTTTTAAAAAAAAACATGCATATTCTAAAAATGACTATTGGTGGGGAG
GTGTAAATAAGTCATACCTTCTTAAAACAGAAAATTTAAGTAAAGTCTTTTAAATGAAACCTGTAAAAGTATTGACTCTTCTACCAAGTT
GGTATGATATTCCAGGCAGCTCAATGATTATCACATTTGAGACCCTGTGTTTGAAGCATTTACAGGCAATGTACAGCAACAGAGGTACCT
CTTGGTGTATAGTATTTACATTCTCTTTTAGGTAGAAGAGGCAATTTTACCCTTATTTCACATGGTTAGAAATTTAAAGCAAGATCATTT
ACCCAAGGATAGGTGTTTGGTAATGTTGAAGGAGTTAGTCTGGCTTCATGTTTTACATCTTCAACTAAAATCCCATACTATCTGCTTGGA
TTTGGAGAGCCAAAAAATAAAGCTGATTGTCATGTGATTAAATATCTGATCAACAGGTATGAATATAACTTAAATCAGCATATTTTTGCC
ATGGTAATAAATTGTCCTATAAACTATTTATATATTTTTGTTCTTCATAATTATCACTAATAAGCATCAGTTTGTTGTTTTTAAAAGGAT
ATTTAAGTGAGCATTTTCTAGTTCATATGAAAATAACCATAGTACAGGATGATTTCTGTCCACACAAAGGTTAAATTAGATTGCACAGTT
AATTTTCACTTATATTTATGGTACTATTATGTGGGTGATGCCTTTTTCTTTTAAGCCCAGTACATATATTATGCCTGCCTAAGTTCTGAA
CTGGGGCTGTATTTCAGTAGTTGTAGAATTATTGATATTTAGTTTTGATAGCTAATGTTTAATTGTTTGGATCTGCACAGTTTGGTTTTT
GCACAAAAGTCATTTAAAAAAATCTGAGTAATTGTCAAATATTAAAAGAAAGATATTCTTCCTGTAAGGAATACAGTTTTTAGTCAAAGT
GGCCATTACATCCTCTTTTTAATTTACATAATACAGATACTTGAGAAAGTTGTTGTGGTGTTGTATGCCAAGAAAATTCTTTTTATTGGT
GCCTATATTGTAACAATTATTTTTAATGCATTGTATTTTGAAGTAACGGTTCAGTTAAATTTTTCACCTGCTGTGTAACTGAAACACAAT
TACAGTTTATAATCATCTGTAGAAGTCTGGAGATAATTTTGCAACTCATGTTATGGGTTAAATGAATATTTTTGTAAAAGTAAAAGCAAC
AAATTTATAAATTGATTATTTGAAACTTTACAACACAATTGCATCCCAAATACAAATTGTATTGCTTATTCATTATAGCTATTCGTCCTG

>30214_30214_2_FGF13-MST4_FGF13_chrX_138286221_ENST00000370603_MST4_chrX_131188659_ENST00000394334_length(amino acids)=406AA_BP=2
MLLRNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIME
YLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV
IQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKK
TSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSCLSMIITPAFAELKQQDEN

--------------------------------------------------------------
>30214_30214_3_FGF13-MST4_FGF13_chrX_138286221_ENST00000370603_MST4_chrX_131188659_ENST00000481105_length(transcript)=1626nt_BP=49nt
ATGAGTGGAAAGGTGACCAAGCCCAAAGAGGAGAAAGATGCTTCTAAGGAATAACATAGCTGATCCAGAAGAACTGTTCACAAAATTAGA
GCGCATTGGGAAAGGCTCATTTGGGGAAGTTTTCAAAGGAATTGATAACCGTACCCAGCAAGTCGTTGCTATTAAAATCATAGACCTTGA
GGAAGCCGAAGATGAAATAGAAGACATTCAGCAAGAAATAACTGTCTTGAGTCAATGTGACAGCTCATATGTAACAAAATACTATGGGTC
ATATTTAAAGGATCATGGGATTAGCAGACACCTGAAGTTCCAGCAGATGGAGGTGTTACTACATAGCAGAAAACTGGGGTCTAAATTATG
GATAATAATGGAATACCTGGGCGGTGGTTCAGCACTGGATCTTCTTCGAGCTGGTCCATTTGATGAGTTCCAGATTGCTACCATGCTAAA
GGAAATTTTAAAAGGTCTGGACTATCTGCATTCAGAAAAGAAAATTCACCGAGACATAAAAGCTGCCAATGTCTTGCTCTCAGAACAAGG
AGATGTTAAACTTGCTGATTTTGGAGTTGCTGGTCAGCTGACAGATACACAGATTAAAAGAAATACCTTTGTGGGAACTCCATTTTGGAT
GGCTCCTGAAGTTATTCAACAGTCAGCTTATGACTCAAAAGCTGACATTTGGTCATTGGGAATTACTGCTATTGAACTAGCCAAGGGAGA
GCCACCTAACTCCGATATGCATCCAATGAGAGTTCTGTTTCTTATTCCCAAAAACAATCCTCCAACTCTTGTTGGAGACTTTACTAAGTC
TTTTAAGGAGTTTATTGATGCTTGCCTGAACAAAGATCCATCATTTCGTCCTACAGCAAAAGAACTTCTGAAACACAAATTCATTGTAAA
AAATTCAAAGAAGACTTCTTATCTGACTGAACTGATAGATCGTTTTAAGAGATGGAAGGCAGAAGGACACAGTGATGATGAATCTGATTC
CGAGGGCTCTGATTCGGAATCTACCAGCAGGGAAAACAATACTCATCCTGAATGGAGCTTTACCACCGTACGAAAGAAGCCTGATCCAAA
GAAAGTACAGAATGGGGCAGAGCAAGATCTTGTGCAAACCCTGAGTTGTTTGTCTATGATAATCACACCTGCATTTGCTGAACTTAAACA
GCAGGACGAGAATAACGCTAGCAGGAATCAGGCGATTGAAGAACTCGAGAAAAGTATTGCTGTGGCTGAAGCCGCCTGTCCCGGCATCAC
AGATAAAATGGTGAAGAAACTAATTGAAAAATTTCAAAAGTGTTCAGCAGACGAATCCCCCTAAGAAACTTATTATTGGCTTCTGTTTCA
TATGGACCCAGAGAGCCCCACCAAACCTACGTCAAGATTAACAATGCTTAACCCATGAGCTCCATGTGCCTTTTGGATCTTTGCAACACT
GAAGATTTGGAAGAAGCTATTAAACTATTTTGTGATGGCGTTTATCATTTTATATTTTGAAAGGATTATTTTGTAAGGAATAACTTTTAA
TACTATAGTTTCACCTGTATTCTAGTAAATGTTGAGACACCGTTTTGCTTTTAAGTATCCCTATTTCTTAAGTTACGAGGATGAATACCT

>30214_30214_3_FGF13-MST4_FGF13_chrX_138286221_ENST00000370603_MST4_chrX_131188659_ENST00000481105_length(amino acids)=428AA_BP=2
MLLRNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKDHGISRHLK
FQQMEVLLHSRKLGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQ
LTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKD
PSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQ

--------------------------------------------------------------
>30214_30214_4_FGF13-MST4_FGF13_chrX_138286221_ENST00000541469_MST4_chrX_131188659_ENST00000354719_length(transcript)=2970nt_BP=49nt
ATGAGTGGAAAGGTGACCAAGCCCAAAGAGGAGAAAGATGCTTCTAAGGAATAACATAGCTGATCCAGAAGAACTGTTCACAAAATTAGA
GCGCATTGGGAAAGGCTCATTTGGGGAAGTTTTCAAAGGAATTGATAACCGTACCCAGCAAGTCGTTGCTATTAAAATCATAGACCTTGA
GGAAGCCGAAGATGAAATAGAAGACATTCAGCAAGAAATAACTGTCTTGAGTCAATGTGACAGCTCATATGTAACAAAATACTATGGGTC
ATATTTAAAGGGGTCTAAATTATGGATAATAATGGAATACCTGGGCGGTGGTTCAGCACTGGATCTTCTTCGAGCTGGTCCATTTGATGA
GTTCCAGATTGCTACCATGCTAAAGGAAATTTTAAAAGGTCTGGACTATCTGCATTCAGAAAAGAAAATTCACCGAGACATAAAAGCTGC
CAATGTCTTGCTCTCAGAACAAGGAGATGTTAAACTTGCTGATTTTGGAGTTGCTGGTCAGCTGACAGATACACAGATTAAAAGAAATAC
CTTTGTGGGAACTCCATTTTGGATGGCTCCTGAAGTTATTCAACAGTCAGCTTATGACTCAAAAGCTGACATTTGGTCATTGGGAATTAC
TGCTATTGAACTAGCCAAGGGAGAGCCACCTAACTCCGATATGCATCCAATGAGAGTTCTGTTTCTTATTCCCAAAAACAATCCTCCAAC
TCTTGTTGGAGACTTTACTAAGTCTTTTAAGGAGTTTATTGATGCTTGCCTGAACAAAGATCCATCATTTCGTCCTACAGCAAAAGAACT
TCTGAAACACAAATTCATTGTAAAAAATTCAAAGAAGACTTCTTATCTGACTGAACTGATAGATCGTTTTAAGAGATGGAAGGCAGAAGG
ACACAGTGATGATGAATCTGATTCCGAGGGCTCTGATTCGGAATCTACCAGCAGGGAAAACAATACTCATCCTGAATGGAGCTTTACCAC
CGTACGAAAGAAGCCTGATCCAAAGAAAGTACAGAATGGGGCACAGGACGAGAATAACGCTAGCAGGAATCAGGCGATTGAAGAACTCGA
GAAAAGTATTGCTGTGGCTGAAGCCGCCTGTCCCGGCATCACAGATAAAATGGTGAAGAAACTAATTGAAAAATTTCAAAAGTGTTCAGC
AGACGAATCCCCCTAAGAAACTTATTATTGGCTTCTGTTTCATATGGACCCAGAGAGCCCCACCAAACCTACGTCAAGATTAACAATGCT
TAACCCATGAGCTCCATGTGCCTTTTGGATCTTTGCAACACTGAAGATTTGGAAGAAGCTATTAAACTATTTTGTGATGGCGTTTATCAT
TTTATATTTTGAAAGGATTATTTTGTAAGGAATAACTTTTAATACTATAGTTTCACCTGTATTCTAGTAAATGTTGAGACACCGTTTTGC
TTTTAAGTATCCCTATTTCTTAAGTTACGAGGATGAATACCTTTCACATTTTGATCTTTAGTTGACTCTACAGTCATGAAACATACAGGT
CTTTCAAAGTCATTCTCAATATTCAGCTTTTGTAAATTATCAAGCTTCAAAAAGCTTTTTTTTTTAAAAAAAAACATGCATATTCTAAAA
ATGACTATTGGTGGGGAGGTGTAAATAAGTCATACCTTCTTAAAACAGAAAATTTAAGTAAAGTCTTTTAAATGAAACCTGTAAAAGTAT
TGACTCTTCTACCAAGTTGGTATGATATTCCAGGCAGCTCAATGATTATCACATTTGAGACCCTGTGTTTGAAGCATTTACAGGCAATGT
ACAGCAACAGAGGTACCTCTTGGTGTATAGTATTTACATTCTCTTTTAGGTAGAAGAGGCAATTTTACCCTTATTTCACATGGTTAGAAA
TTTAAAGCAAGATCATTTACCCAAGGATAGGTGTTTGGTAATGTTGAAGGAGTTAGTCTGGCTTCATGTTTTACATCTTCAACTAAAATC
CCATACTATCTGCTTGGATTTGGAGAGCCAAAAAATAAAGCTGATTGTCATGTGATTAAATATCTGATCAACAGGTATGAATATAACTTA
AATCAGCATATTTTTGCCATGGTAATAAATTGTCCTATAAACTATTTATATATTTTTGTTCTTCATAATTATCACTAATAAGCATCAGTT
TGTTGTTTTTAAAAGGATATTTAAGTGAGCATTTTCTAGTTCATATGAAAATAACCATAGTACAGGATGATTTCTGTCCACACAAAGGTT
AAATTAGATTGCACAGTTAATTTTCACTTATATTTATGGTACTATTATGTGGGTGATGCCTTTTTCTTTTAAGCCCAGTACATATATTAT
GCCTGCCTAAGTTCTGAACTGGGGCTGTATTTCAGTAGTTGTAGAATTATTGATATTTAGTTTTGATAGCTAATGTTTAATTGTTTGGAT
CTGCACAGTTTGGTTTTTGCACAAAAGTCATTTAAAAAAATCTGAGTAATTGTCAAATATTAAAAGAAAGATATTCTTCCTGTAAGGAAT
ACAGTTTTTAGTCAAAGTGGCCATTACATCCTCTTTTTAATTTACATAATACAGATACTTGAGAAAGTTGTTGTGGTGTTGTATGCCAAG
AAAATTCTTTTTATTGGTGCCTATATTGTAACAATTATTTTTAATGCATTGTATTTTGAAGTAACGGTTCAGTTAAATTTTTCACCTGCT
GTGTAACTGAAACACAATTACAGTTTATAATCATCTGTAGAAGTCTGGAGATAATTTTGCAACTCATGTTATGGGTTAAATGAATATTTT
TGTAAAAGTAAAAGCAACAAATTTATAAATTGATTATTTGAAACTTTACAACACAATTGCATCCCAAATACAAATTGTATTGCTTATTCA
TTATAGCTATTCGTCCTGTAATCTGTTTCTAGGTGAAGCATACTCCAGTGTTTTAGGGGTTTTGAAAATAAATATTTAAATTTCACAGTC

>30214_30214_4_FGF13-MST4_FGF13_chrX_138286221_ENST00000541469_MST4_chrX_131188659_ENST00000354719_length(amino acids)=382AA_BP=2
MLLRNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIME
YLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV
IQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKK
TSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAQDENNASRNQAIEELEKSIAVAEAACPG

--------------------------------------------------------------
>30214_30214_5_FGF13-MST4_FGF13_chrX_138286221_ENST00000541469_MST4_chrX_131188659_ENST00000394334_length(transcript)=3042nt_BP=49nt
ATGAGTGGAAAGGTGACCAAGCCCAAAGAGGAGAAAGATGCTTCTAAGGAATAACATAGCTGATCCAGAAGAACTGTTCACAAAATTAGA
GCGCATTGGGAAAGGCTCATTTGGGGAAGTTTTCAAAGGAATTGATAACCGTACCCAGCAAGTCGTTGCTATTAAAATCATAGACCTTGA
GGAAGCCGAAGATGAAATAGAAGACATTCAGCAAGAAATAACTGTCTTGAGTCAATGTGACAGCTCATATGTAACAAAATACTATGGGTC
ATATTTAAAGGGGTCTAAATTATGGATAATAATGGAATACCTGGGCGGTGGTTCAGCACTGGATCTTCTTCGAGCTGGTCCATTTGATGA
GTTCCAGATTGCTACCATGCTAAAGGAAATTTTAAAAGGTCTGGACTATCTGCATTCAGAAAAGAAAATTCACCGAGACATAAAAGCTGC
CAATGTCTTGCTCTCAGAACAAGGAGATGTTAAACTTGCTGATTTTGGAGTTGCTGGTCAGCTGACAGATACACAGATTAAAAGAAATAC
CTTTGTGGGAACTCCATTTTGGATGGCTCCTGAAGTTATTCAACAGTCAGCTTATGACTCAAAAGCTGACATTTGGTCATTGGGAATTAC
TGCTATTGAACTAGCCAAGGGAGAGCCACCTAACTCCGATATGCATCCAATGAGAGTTCTGTTTCTTATTCCCAAAAACAATCCTCCAAC
TCTTGTTGGAGACTTTACTAAGTCTTTTAAGGAGTTTATTGATGCTTGCCTGAACAAAGATCCATCATTTCGTCCTACAGCAAAAGAACT
TCTGAAACACAAATTCATTGTAAAAAATTCAAAGAAGACTTCTTATCTGACTGAACTGATAGATCGTTTTAAGAGATGGAAGGCAGAAGG
ACACAGTGATGATGAATCTGATTCCGAGGGCTCTGATTCGGAATCTACCAGCAGGGAAAACAATACTCATCCTGAATGGAGCTTTACCAC
CGTACGAAAGAAGCCTGATCCAAAGAAAGTACAGAATGGGGCAGAGCAAGATCTTGTGCAAACCCTGAGTTGTTTGTCTATGATAATCAC
ACCTGCATTTGCTGAACTTAAACAGCAGGACGAGAATAACGCTAGCAGGAATCAGGCGATTGAAGAACTCGAGAAAAGTATTGCTGTGGC
TGAAGCCGCCTGTCCCGGCATCACAGATAAAATGGTGAAGAAACTAATTGAAAAATTTCAAAAGTGTTCAGCAGACGAATCCCCCTAAGA
AACTTATTATTGGCTTCTGTTTCATATGGACCCAGAGAGCCCCACCAAACCTACGTCAAGATTAACAATGCTTAACCCATGAGCTCCATG
TGCCTTTTGGATCTTTGCAACACTGAAGATTTGGAAGAAGCTATTAAACTATTTTGTGATGGCGTTTATCATTTTATATTTTGAAAGGAT
TATTTTGTAAGGAATAACTTTTAATACTATAGTTTCACCTGTATTCTAGTAAATGTTGAGACACCGTTTTGCTTTTAAGTATCCCTATTT
CTTAAGTTACGAGGATGAATACCTTTCACATTTTGATCTTTAGTTGACTCTACAGTCATGAAACATACAGGTCTTTCAAAGTCATTCTCA
ATATTCAGCTTTTGTAAATTATCAAGCTTCAAAAAGCTTTTTTTTTTAAAAAAAAACATGCATATTCTAAAAATGACTATTGGTGGGGAG
GTGTAAATAAGTCATACCTTCTTAAAACAGAAAATTTAAGTAAAGTCTTTTAAATGAAACCTGTAAAAGTATTGACTCTTCTACCAAGTT
GGTATGATATTCCAGGCAGCTCAATGATTATCACATTTGAGACCCTGTGTTTGAAGCATTTACAGGCAATGTACAGCAACAGAGGTACCT
CTTGGTGTATAGTATTTACATTCTCTTTTAGGTAGAAGAGGCAATTTTACCCTTATTTCACATGGTTAGAAATTTAAAGCAAGATCATTT
ACCCAAGGATAGGTGTTTGGTAATGTTGAAGGAGTTAGTCTGGCTTCATGTTTTACATCTTCAACTAAAATCCCATACTATCTGCTTGGA
TTTGGAGAGCCAAAAAATAAAGCTGATTGTCATGTGATTAAATATCTGATCAACAGGTATGAATATAACTTAAATCAGCATATTTTTGCC
ATGGTAATAAATTGTCCTATAAACTATTTATATATTTTTGTTCTTCATAATTATCACTAATAAGCATCAGTTTGTTGTTTTTAAAAGGAT
ATTTAAGTGAGCATTTTCTAGTTCATATGAAAATAACCATAGTACAGGATGATTTCTGTCCACACAAAGGTTAAATTAGATTGCACAGTT
AATTTTCACTTATATTTATGGTACTATTATGTGGGTGATGCCTTTTTCTTTTAAGCCCAGTACATATATTATGCCTGCCTAAGTTCTGAA
CTGGGGCTGTATTTCAGTAGTTGTAGAATTATTGATATTTAGTTTTGATAGCTAATGTTTAATTGTTTGGATCTGCACAGTTTGGTTTTT
GCACAAAAGTCATTTAAAAAAATCTGAGTAATTGTCAAATATTAAAAGAAAGATATTCTTCCTGTAAGGAATACAGTTTTTAGTCAAAGT
GGCCATTACATCCTCTTTTTAATTTACATAATACAGATACTTGAGAAAGTTGTTGTGGTGTTGTATGCCAAGAAAATTCTTTTTATTGGT
GCCTATATTGTAACAATTATTTTTAATGCATTGTATTTTGAAGTAACGGTTCAGTTAAATTTTTCACCTGCTGTGTAACTGAAACACAAT
TACAGTTTATAATCATCTGTAGAAGTCTGGAGATAATTTTGCAACTCATGTTATGGGTTAAATGAATATTTTTGTAAAAGTAAAAGCAAC
AAATTTATAAATTGATTATTTGAAACTTTACAACACAATTGCATCCCAAATACAAATTGTATTGCTTATTCATTATAGCTATTCGTCCTG

>30214_30214_5_FGF13-MST4_FGF13_chrX_138286221_ENST00000541469_MST4_chrX_131188659_ENST00000394334_length(amino acids)=406AA_BP=2
MLLRNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIME
YLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEV
IQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKK
TSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSCLSMIITPAFAELKQQDEN

--------------------------------------------------------------
>30214_30214_6_FGF13-MST4_FGF13_chrX_138286221_ENST00000541469_MST4_chrX_131188659_ENST00000481105_length(transcript)=1626nt_BP=49nt
ATGAGTGGAAAGGTGACCAAGCCCAAAGAGGAGAAAGATGCTTCTAAGGAATAACATAGCTGATCCAGAAGAACTGTTCACAAAATTAGA
GCGCATTGGGAAAGGCTCATTTGGGGAAGTTTTCAAAGGAATTGATAACCGTACCCAGCAAGTCGTTGCTATTAAAATCATAGACCTTGA
GGAAGCCGAAGATGAAATAGAAGACATTCAGCAAGAAATAACTGTCTTGAGTCAATGTGACAGCTCATATGTAACAAAATACTATGGGTC
ATATTTAAAGGATCATGGGATTAGCAGACACCTGAAGTTCCAGCAGATGGAGGTGTTACTACATAGCAGAAAACTGGGGTCTAAATTATG
GATAATAATGGAATACCTGGGCGGTGGTTCAGCACTGGATCTTCTTCGAGCTGGTCCATTTGATGAGTTCCAGATTGCTACCATGCTAAA
GGAAATTTTAAAAGGTCTGGACTATCTGCATTCAGAAAAGAAAATTCACCGAGACATAAAAGCTGCCAATGTCTTGCTCTCAGAACAAGG
AGATGTTAAACTTGCTGATTTTGGAGTTGCTGGTCAGCTGACAGATACACAGATTAAAAGAAATACCTTTGTGGGAACTCCATTTTGGAT
GGCTCCTGAAGTTATTCAACAGTCAGCTTATGACTCAAAAGCTGACATTTGGTCATTGGGAATTACTGCTATTGAACTAGCCAAGGGAGA
GCCACCTAACTCCGATATGCATCCAATGAGAGTTCTGTTTCTTATTCCCAAAAACAATCCTCCAACTCTTGTTGGAGACTTTACTAAGTC
TTTTAAGGAGTTTATTGATGCTTGCCTGAACAAAGATCCATCATTTCGTCCTACAGCAAAAGAACTTCTGAAACACAAATTCATTGTAAA
AAATTCAAAGAAGACTTCTTATCTGACTGAACTGATAGATCGTTTTAAGAGATGGAAGGCAGAAGGACACAGTGATGATGAATCTGATTC
CGAGGGCTCTGATTCGGAATCTACCAGCAGGGAAAACAATACTCATCCTGAATGGAGCTTTACCACCGTACGAAAGAAGCCTGATCCAAA
GAAAGTACAGAATGGGGCAGAGCAAGATCTTGTGCAAACCCTGAGTTGTTTGTCTATGATAATCACACCTGCATTTGCTGAACTTAAACA
GCAGGACGAGAATAACGCTAGCAGGAATCAGGCGATTGAAGAACTCGAGAAAAGTATTGCTGTGGCTGAAGCCGCCTGTCCCGGCATCAC
AGATAAAATGGTGAAGAAACTAATTGAAAAATTTCAAAAGTGTTCAGCAGACGAATCCCCCTAAGAAACTTATTATTGGCTTCTGTTTCA
TATGGACCCAGAGAGCCCCACCAAACCTACGTCAAGATTAACAATGCTTAACCCATGAGCTCCATGTGCCTTTTGGATCTTTGCAACACT
GAAGATTTGGAAGAAGCTATTAAACTATTTTGTGATGGCGTTTATCATTTTATATTTTGAAAGGATTATTTTGTAAGGAATAACTTTTAA
TACTATAGTTTCACCTGTATTCTAGTAAATGTTGAGACACCGTTTTGCTTTTAAGTATCCCTATTTCTTAAGTTACGAGGATGAATACCT

>30214_30214_6_FGF13-MST4_FGF13_chrX_138286221_ENST00000541469_MST4_chrX_131188659_ENST00000481105_length(amino acids)=428AA_BP=2
MLLRNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKDHGISRHLK
FQQMEVLLHSRKLGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQ
LTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKD
PSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FGF13-MST4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FGF13-MST4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FGF13-MST4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource