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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:FGFR2-C10orf118 (FusionGDB2 ID:30278) |
Fusion Gene Summary for FGFR2-C10orf118 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FGFR2-C10orf118 | Fusion gene ID: 30278 | Hgene | Tgene | Gene symbol | FGFR2 | C10orf118 | Gene ID | 2263 | 55088 |
| Gene name | fibroblast growth factor receptor 2 | coiled-coil domain containing 186 | |
| Synonyms | BBDS|BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25 | C10orf118|CCCP-1|golgin104 | |
| Cytomap | 10q26.13 | 10q25.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | fibroblast growth factor receptor 2BEK fibroblast growth factor receptorbacteria-expressed kinasekeratinocyte growth factor receptorprotein tyrosine kinase, receptor like 14 | coiled-coil domain-containing protein 186CTCL tumor antigen HD-CL-01/L14-2CTCL tumor antigen L14-2 | |
| Modification date | 20200322 | 20200313 | |
| UniProtAcc | P21802 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000346997, ENST00000351936, ENST00000356226, ENST00000357555, ENST00000358487, ENST00000360144, ENST00000369056, ENST00000369059, ENST00000369060, ENST00000369061, ENST00000457416, ENST00000478859, ENST00000359354, ENST00000490349, | ENST00000369285, ENST00000369286, ENST00000497592, ENST00000543782, ENST00000369287, | |
| Fusion gene scores | * DoF score | 24 X 20 X 12=5760 | 1 X 1 X 1=1 |
| # samples | 38 | 1 | |
| ** MAII score | log2(38/5760*10)=-3.92199748799873 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: FGFR2 [Title/Abstract] AND C10orf118 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | FGFR2(123243212)-C10orf118(115910979), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | FGFR2-C10orf118 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. FGFR2-C10orf118 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. FGFR2-C10orf118 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | FGFR2 | GO:0008284 | positive regulation of cell proliferation | 8663044 |
| Hgene | FGFR2 | GO:0008543 | fibroblast growth factor receptor signaling pathway | 8663044|15629145 |
| Hgene | FGFR2 | GO:0018108 | peptidyl-tyrosine phosphorylation | 15629145|16844695 |
| Hgene | FGFR2 | GO:0046777 | protein autophosphorylation | 15629145 |
| Fusion gene breakpoints across FGFR2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across C10orf118 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | CHOL | TCGA-W5-AA2Z-01A | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
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Fusion Gene ORF analysis for FGFR2-C10orf118 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000346997 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000346997 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000346997 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000346997 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000351936 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000351936 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000351936 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000351936 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000356226 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000356226 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000356226 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000356226 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000357555 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000357555 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000357555 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000357555 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000358487 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000358487 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000358487 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000358487 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000360144 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000360144 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000360144 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000360144 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369056 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369056 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369056 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369056 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369059 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369059 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369059 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369059 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369060 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369060 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369060 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369060 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369061 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369061 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369061 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000369061 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000457416 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000457416 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000457416 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000457416 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000478859 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000478859 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000478859 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| 5CDS-intron | ENST00000478859 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000351936 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000356226 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000357555 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000358487 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000360144 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000369059 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000369060 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000457416 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| Frame-shift | ENST00000478859 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| In-frame | ENST00000346997 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| In-frame | ENST00000369056 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| In-frame | ENST00000369061 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-3CDS | ENST00000359354 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-3CDS | ENST00000490349 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000359354 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000359354 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000359354 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000359354 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000490349 | ENST00000369285 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000490349 | ENST00000369286 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000490349 | ENST00000497592 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| intron-intron | ENST00000490349 | ENST00000543782 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000369061 | FGFR2 | chr10 | 123243212 | - | ENST00000369287 | C10orf118 | chr10 | 115910979 | - | 8334 | 2115 | 48 | 4052 | 1334 |
| ENST00000346997 | FGFR2 | chr10 | 123243212 | - | ENST00000369287 | C10orf118 | chr10 | 115910979 | - | 8526 | 2307 | 12 | 4244 | 1410 |
| ENST00000369056 | FGFR2 | chr10 | 123243212 | - | ENST00000369287 | C10orf118 | chr10 | 115910979 | - | 8547 | 2328 | 24 | 4265 | 1413 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000369061 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - | 0.000100885 | 0.99989915 |
| ENST00000346997 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - | 7.68E-05 | 0.9999232 |
| ENST00000369056 | ENST00000369287 | FGFR2 | chr10 | 123243212 | - | C10orf118 | chr10 | 115910979 | - | 8.84E-05 | 0.99991167 |
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Fusion Genomic Features for FGFR2-C10orf118 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for FGFR2-C10orf118 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:123243212/chr10:115910979) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FGFR2 | . |
| FUNCTION: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1. {ECO:0000269|PubMed:12529371, ECO:0000269|PubMed:15190072, ECO:0000269|PubMed:15629145, ECO:0000269|PubMed:16384934, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:17311277, ECO:0000269|PubMed:17623664, ECO:0000269|PubMed:18374639, ECO:0000269|PubMed:19103595, ECO:0000269|PubMed:19387476, ECO:0000269|PubMed:19410646, ECO:0000269|PubMed:21596750, ECO:0000269|PubMed:8663044}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 154_247 | 765 | 820.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 256_358 | 765 | 820.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 25_125 | 765 | 820.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 154_247 | 765 | 786.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 256_358 | 765 | 786.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 25_125 | 765 | 786.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 154_247 | 650 | 705.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 256_358 | 650 | 705.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 25_125 | 650 | 705.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 154_247 | 678 | 708.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 256_358 | 678 | 708.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 25_125 | 678 | 708.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 154_247 | 767 | 822.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 256_358 | 767 | 822.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 25_125 | 767 | 822.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 481_770 | 767 | 822.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 154_247 | 679 | 681.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 256_358 | 679 | 681.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 25_125 | 679 | 681.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 154_247 | 768 | 770.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 256_358 | 768 | 770.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 25_125 | 768 | 770.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 481_770 | 768 | 770.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 154_247 | 651 | 706.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 256_358 | 651 | 706.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 25_125 | 651 | 706.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 154_247 | 655 | 710.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 256_358 | 655 | 710.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 25_125 | 655 | 710.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 154_247 | 768 | 823.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 256_358 | 768 | 823.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 25_125 | 768 | 823.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 481_770 | 768 | 823.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 487_495 | 765 | 820.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 565_567 | 765 | 820.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 487_495 | 765 | 786.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 565_567 | 765 | 786.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 487_495 | 650 | 705.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 565_567 | 650 | 705.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 487_495 | 678 | 708.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 565_567 | 678 | 708.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 487_495 | 767 | 822.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 565_567 | 767 | 822.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 487_495 | 679 | 681.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 565_567 | 679 | 681.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 487_495 | 768 | 770.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 565_567 | 768 | 770.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 487_495 | 651 | 706.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 565_567 | 651 | 706.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 487_495 | 655 | 710.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 565_567 | 655 | 710.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 487_495 | 768 | 823.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 565_567 | 768 | 823.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 161_178 | 765 | 820.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 161_178 | 765 | 786.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 161_178 | 650 | 705.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 161_178 | 678 | 708.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 161_178 | 767 | 822.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 161_178 | 679 | 681.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 161_178 | 768 | 770.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 161_178 | 651 | 706.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 161_178 | 655 | 710.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 161_178 | 768 | 823.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 22_377 | 765 | 820.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 22_377 | 765 | 786.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 22_377 | 650 | 705.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 22_377 | 678 | 708.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 22_377 | 767 | 822.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 22_377 | 679 | 681.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 22_377 | 768 | 770.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 22_377 | 651 | 706.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 22_377 | 655 | 710.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 22_377 | 768 | 823.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 378_398 | 765 | 820.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 378_398 | 765 | 786.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 378_398 | 650 | 705.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 378_398 | 678 | 708.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 378_398 | 767 | 822.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 378_398 | 679 | 681.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 378_398 | 768 | 770.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 378_398 | 651 | 706.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 378_398 | 655 | 710.0 | Transmembrane | Helical |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 378_398 | 768 | 823.0 | Transmembrane | Helical |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369285 | 0 | 3 | 201_712 | 0 | 212.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369285 | 0 | 3 | 759_803 | 0 | 212.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369285 | 0 | 3 | 855_894 | 0 | 212.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369286 | 0 | 2 | 201_712 | 0 | 212.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369286 | 0 | 2 | 759_803 | 0 | 212.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369286 | 0 | 2 | 855_894 | 0 | 212.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369287 | 2 | 16 | 759_803 | 253 | 899.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369287 | 2 | 16 | 855_894 | 253 | 899.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369285 | 0 | 3 | 710_747 | 0 | 212.0 | Compositional bias | Note=Ser-rich | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369286 | 0 | 2 | 710_747 | 0 | 212.0 | Compositional bias | Note=Ser-rich | |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369287 | 2 | 16 | 710_747 | 253 | 899.0 | Compositional bias | Note=Ser-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 481_770 | 765 | 820.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 481_770 | 765 | 786.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 481_770 | 650 | 705.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 481_770 | 678 | 708.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 154_247 | 0 | 255.0 | Domain | Note=Ig-like C2-type 2 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 256_358 | 0 | 255.0 | Domain | Note=Ig-like C2-type 3 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 25_125 | 0 | 255.0 | Domain | Note=Ig-like C2-type 1 |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 481_770 | 0 | 255.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 481_770 | 679 | 681.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 481_770 | 651 | 706.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 481_770 | 655 | 710.0 | Domain | Protein kinase |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 487_495 | 0 | 255.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 565_567 | 0 | 255.0 | Nucleotide binding | ATP |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 161_178 | 0 | 255.0 | Region | Note=Heparin-binding |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000346997 | - | 16 | 17 | 399_821 | 765 | 820.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000351936 | - | 17 | 18 | 399_821 | 765 | 786.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000356226 | - | 15 | 16 | 399_821 | 650 | 705.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000357555 | - | 16 | 17 | 399_821 | 678 | 708.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000358487 | - | 17 | 18 | 399_821 | 767 | 822.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 22_377 | 0 | 255.0 | Topological domain | Extracellular |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 399_821 | 0 | 255.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000360144 | - | 16 | 17 | 399_821 | 679 | 681.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369056 | - | 16 | 17 | 399_821 | 768 | 770.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369060 | - | 15 | 16 | 399_821 | 651 | 706.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000369061 | - | 14 | 15 | 399_821 | 655 | 710.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000457416 | - | 17 | 18 | 399_821 | 768 | 823.0 | Topological domain | Cytoplasmic |
| Hgene | FGFR2 | chr10:123243212 | chr10:115910979 | ENST00000359354 | - | 1 | 7 | 378_398 | 0 | 255.0 | Transmembrane | Helical |
| Tgene | C10orf118 | chr10:123243212 | chr10:115910979 | ENST00000369287 | 2 | 16 | 201_712 | 253 | 899.0 | Coiled coil | Ontology_term=ECO:0000255 |
Top |
Fusion Gene Sequence for FGFR2-C10orf118 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >30278_30278_1_FGFR2-C10orf118_FGFR2_chr10_123243212_ENST00000346997_C10orf118_chr10_115910979_ENST00000369287_length(transcript)=8526nt_BP=2307nt GGTACCGTAACCATGGTCAGCTGGGGTCGTTTCATCTGCCTGGTCGTGGTCACCATGGCAACCTTGTCCCTGGCCCGGCCCTCCTTCAGT TTAGTTGAGGATACCACATTAGAGCCAGAAGAGCCACCAACCAAATACCAAATCTCTCAACCAGAAGTGTACGTGGCTGCGCCAGGGGAG TCGCTAGAGGTGCGCTGCCTGTTGAAAGATGCCGCCGTGATCAGTTGGACTAAGGATGGGGTGCACTTGGGGCCCAACAATAGGACAGTG CTTATTGGGGAGTACTTGCAGATAAAGGGCGCCACGCCTAGAGACTCCGGCCTCTATGCTTGTACTGCCAGTAGGACTGTAGACAGTGAA ACTTGGTACTTCATGGTGAATGTCACAGATGCCATCTCATCCGGAGATGATGAGGATGACACCGATGGTGCGGAAGATTTTGTCAGTGAG AACAGTAACAACAAGAGAGCACCATACTGGACCAACACAGAAAAGATGGAAAAGCGGCTCCATGCTGTGCCTGCGGCCAACACTGTCAAG TTTCGCTGCCCAGCCGGGGGGAACCCAATGCCAACCATGCGGTGGCTGAAAAACGGGAAGGAGTTTAAGCAGGAGCATCGCATTGGAGGC TACAAGGTACGAAACCAGCACTGGAGCCTCATTATGGAAAGTGTGGTCCCATCTGACAAGGGAAATTATACCTGTGTAGTGGAGAATGAA TACGGGTCCATCAATCACACGTACCACCTGGATGTTGTGGAGCGATCGCCTCACCGGCCCATCCTCCAAGCCGGACTGCCGGCAAATGCC TCCACAGTGGTCGGAGGAGACGTAGAGTTTGTCTGCAAGGTTTACAGTGATGCCCAGCCCCACATCCAGTGGATCAAGCACGTGGAAAAG AACGGCAGTAAATACGGGCCCGACGGGCTGCCCTACCTCAAGGTTCTCAAGGCCGCCGGTGTTAACACCACGGACAAAGAGATTGAGGTT CTCTATATTCGGAATGTAACTTTTGAGGACGCTGGGGAATATACGTGCTTGGCGGGTAATTCTATTGGGATATCCTTTCACTCTGCATGG TTGACAGTTCTGCCAGCGCCTGGAAGAGAAAAGGAGATTACAGCTTCCCCAGACTACCTGGAGATAGCCATTTACTGCATAGGGGTCTTC TTAATCGCCTGTATGGTGGTAACAGTCATCCTGTGCCGAATGAAGAACACGACCAAGAAGCCAGACTTCAGCAGCCAGCCGGCTGTGCAC AAGCTGACCAAACGTATCCCCCTGCGGAGACAGGTTTCGGCTGAGTCCAGCTCCTCCATGAACTCCAACACCCCGCTGGTGAGGATAACA ACACGCCTCTCTTCAACGGCAGACACCCCCATGCTGGCAGGGGTCTCCGAGTATGAACTTCCAGAGGACCCAAAATGGGAGTTTCCAAGA GATAAGCTGACACTGGGCAAGCCCCTGGGAGAAGGTTGCTTTGGGCAAGTGGTCATGGCGGAAGCAGTGGGAATTGACAAAGACAAGCCC AAGGAGGCGGTCACCGTGGCCGTGAAGATGTTGAAAGATGATGCCACAGAGAAAGACCTTTCTGATCTGGTGTCAGAGATGGAGATGATG AAGATGATTGGGAAACACAAGAATATCATAAATCTTCTTGGAGCCTGCACACAGGATGGGCCTCTCTATGTCATAGTTGAGTATGCCTCT AAAGGCAACCTCCGAGAATACCTCCGAGCCCGGAGGCCACCCGGGATGGAGTACTCCTATGACATTAACCGTGTTCCTGAGGAGCAGATG ACCTTCAAGGACTTGGTGTCATGCACCTACCAGCTGGCCAGAGGCATGGAGTACTTGGCTTCCCAAAAATGTATTCATCGAGATTTAGCA GCCAGAAATGTTTTGGTAACAGAAAACAATGTGATGAAAATAGCAGACTTTGGACTCGCCAGAGATATCAACAATATAGACTATTACAAA AAGACCACCAATGGGCGGCTTCCAGTCAAGTGGATGGCTCCAGAAGCCCTGTTTGATAGAGTATACACTCATCAGAGTGATGTCTGGTCC TTCGGGGTGTTAATGTGGGAGATCTTCACTTTAGGGGGCTCGCCCTACCCAGGGATTCCCGTGGAGGAACTTTTTAAGCTGCTGAAGGAA GGACACAGAATGGATAAGCCAGCCAACTGCACCAACGAACTGTACATGATGATGAGGGACTGTTGGCATGCAGTGCCCTCCCAGAGACCA ACGTTCAAGCAGTTGGTAGAAGACTTGGATCGAATTCTCACTCTCACAACCAATGAGTTAGAATCAAGAATAGAAGAACTTAATAAAGAA GTTAAAGCTTCCAGAGATCAACTAATAGCTCAAGACGTTACAGCTAAAAATGCAGTTCAGCAGTTACACAAAGAGATGGCCCAACGGATG GAACAGGCCAACAAGAAATGTGAAGAGGCACGCCAAGAAAAAGAAGCAATGGTAATGAAATATGTAAGAGGTGAGAAGGAATCTTTAGAT CTTCGAAAGGAAAAAGAGACACTTGAGAAAAAACTTAGAGATGCAAATAAGGAACTTGAGAAAAACACTAACAAAATTAAGCAGCTTTCT CAGGAGAAAGGACGGTTGCACCAGCTGTATGAAACTAAGGAAGGCGAAACGACTAGACTCATCAGAGAAATAGACAAATTAAAGGAAGAC ATTAACTCTCACGTCATCAAAGTAAAGTGGGCACAAAACAAATTAAAAGCTGAAATGGATTCACACAAGGAAACCAAAGATAAACTCAAA GAAACAACAACAAAATTAACACAAGCAAAGGAAGAAGCAGATCAGATACGAAAAAACTGTCAGGATATGATAAAAACATATCAGGAGTCA GAAGAAATTAAATCAAATGAGCTTGATGCAAAGCTTAGAGTCACAAAAGGAGAACTTGAAAAACAAATGCAAGAAAAATCTGACCAGCTA GAGATGCATCATGCCAAAATAAAGGAACTAGAAGATCTGAAGAGAACATTTAAGGAGGGTATGGATGAGTTAAGAACACTGAGAACAAAG GTGAAATGTCTAGAAGATGAACGATTAAGAACAGAAGATGAATTATCAAAATATAAGGAAATTATTAATCGCCAAAAAGCTGAAATTCAG AATTTATTGGACAAGGTGAAAACTGCAGATCAGCTACAGGAGCAGCTTCAAAGAGGTAAGCAAGAAATTGAAAATTTGAAAGAAGAAGTG GAAAGTCTTAATTCTTTGATTAATGACCTACAAAAAGACATCGAAGGCAGTAGGAAAAGAGAATCTGAGCTGCTGCTGTTTACAGAAAGG CTCACTAGTAAGAATGCACAGCTTCAGTCTGAATCCAATTCTTTGCAGTCACAATTTGATAAAGTTTCCTGTAGTGAAAGTCAGTTACAA AGCCAGTGTGAACAAATGAAACAGACAAATATTAATTTGGAAAGTAGGTTGTTGAAAGAGGAAGAACTGCGAAAAGAGGAAGTCCAAACT CTGCAAGCTGAACTCGCTTGTAGACAAACAGAAGTTAAAGCATTGAGTACCCAGGTAGAAGAATTAAAAGATGAGTTAGTAACTCAGAGA CGTAAACATGCCTCTAGTATCAAGGATCTCACCAAACAACTTCAGCAAGCACGAAGAAAATTAGATCAGGTTGAGAGTGGAAGCTATGAC AAAGAAGTCAGCAGCATGGGAAGTCGTTCTAGTTCATCAGGGTCCCTGAATGCTCGAAGCAGTGCAGAAGATCGATCTCCAGAAAATACT GGGTCCTCAGTAGCTGTGGATAACTTTCCACAAGTAGATAAGGCCATGTTGATTGAGAGAATAGTTAGGCTGCAAAAAGCACATGCCCGG AAAAATGAAAAGATAGAATTTATGGAGGACCACATCAAACAACTGGTGGAAGAAATTAGGAAAAAAACAAAAATAATTCAAAGTTATATT TTACGAGAAGAATCAGGCACACTTTCTTCAGAGGCATCTGATTTTAACAAAGTTCATTTAAGTAGACGGGGTGGCATCATGGCATCTTTA TATACATCCCATCCAGCTGACAATGGATTAACATTGGAGCTCTCTTTGGAAATCAACCGAAAATTACAGGCTGTTTTGGAGGATACGTTA CTAAAAAATATTACTTTGAAGGAAAATCTACAAACACTTGGAACAGAAATAGAACGTCTTATTAAACACCAGCATGAACTAGAACAGAGG ACAAAGAAAACCTAAAACAAGCCTCTTGCTCAGTAAAGAGACAAAAGCCACACAGGAGTAGGTGCCACTGACCTCTATTGTTGGAGACTT TGTTCCACTTTTTGTTTCAGCCAGTAAAAATATTGTTTTGCTTCATCTGTACACAAAAAAATACCCTTTTACAATATGAATGCATTGCTG TATATACTGTAAGACTGAAAGCTTTGATGAAATTTGTTTTTGTATGGTGCAATATGACAGCCTGTCATTGAATCTAAACAACTTAATTTG CTTGTATTCATAAGAAGTGTTGAACATTACAAGGGCTTTTATAAAAAACCCTTTGTTCATATTTCTTCCCTTTAAAATATGTAATGTCAA AAATGACTCACCTTTTAAAAATTATGCATGAAAACAGGTGGTAAACATTCAGTAATACGCTATTTCTCCAACATCAAGACAACTAAAACA AATGATAAAAATGTTTATTTTTACACTCCAGCATATCGGGTGAGTTTTAGGGATGTGTATGAATATTTAAATCTTTTAATTTCAGTTTTA ATGAAAGCTGAACTTAATAGGAAAGCTAGCTCTTGGTAACTAGCAATGATCAGGCATTGTTTGCCTCTGTCAGGTTTTCTTATCTGTTTT AGGTACATTTTTTCAGATTCTGATTGTTTGAGTTAATGGTTGAATTTTTAAAGTTTTTAGTTACTTAAAATATGATTTTAAATTACATAT TAATTTAGAAAATTCCTGTGTTTACTTATATTTTAAATTGTGAAATGGATCCAATCATTAGAACAGAGAGAATAGTTCTTTGAAACTGAA ATACTTTAGTTTTACTGACCTTGTGTAAAGATAATATGAAGAACCAGCTTCCAAAAGAAACCAGCATATGGCACTATAAACTATTTCATT TGAGCACCATTCTTTACCATGGATATATTAATTATGTATTATAGTGGAGTGATCATACAGTTCCCCCAAATGTGATGTTTCAGTGTATTT ATTTAAAACATAAAGTAGACCAGGTGCAGTAGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGCAGGAGGATTACCTGAGGCCA GGAGTTTAAGACCAGCCTTGGCAACATAGCGAGACCCCCATCTCTACAAAGAAATTTTAAAAGATTATCCAGGCATGGTGGTGCATGCCT ATGGTTCCAGCTACTCGGGAGGCTGAAGCGGTAGAATCACTTGAGCACAGGAGGTCAAGGCTGCAGGTGAGCCATGATCGTGTCACTGCA CTCCAGCCTAGGCAACAGAGCAAGACCCTGTCTCTTAAAACAAAAAACCTCACACATACCTAAAATAAGTATATATCTGTAACCAAAGGA ACTTAATTTTAGAGCCAAATTTTTCTATCTTGTTGGATTTTTTACAGTGTTTAAGATAGACACTTAAGTGTTGCCGTAGTATCAATATTT CTGTCATTGAATTTTTTCTCACCCCTTATTATTTCTCACTTACAATTTCTGAGCATGATTTTTCATAATTCATTATCTTCAGATCATTAC TATAATAAGATACCGTGGCTCTTATGCAGATATTGCAGCAAGCCTTGTTTGGTTTGGATTTTTGCATCCCTTTTTCTCCCATTAAGGGAA TTAAGTTTTGGGATGATGGATTAAAAGCCTGTAAAGAATTGTTTGGGCTCTAAAAGTTGGGCTCATGGTGGCAATATCCTTTTAATGTGT TTTAACATTTTTTAATCAACATCGTTTAAAAATAATTTACTAAGGATTAGATTATTTAATGAATGTCTTTTTTTCTATATATTGAATTAG ATGTTATCCCAAAAAAAATATCTTTTCACTTCAAAATGAAAATATATGTTCAAAGATGTTTTATTTTTAGAATAGTTATAAAAAGTATTA GTCTTAACATAATGTGTCTTGTTCTTTTTACCAATAATAATTTATCAAAATAAGAGGGAAAGTGCAATCAAATCTGAATTATTTTACTAT TTGTTTCTAGACACACTACTTAACACTCCTAAAGACTACTTTGAGTAGGCAACATAACTAAATTTTTCTAGTTTCTTATGATACAGGTTC ATAAACTACAATATTTGGATTTTTTTCCCCAAGGCACAAAATGTATAATGGAGACCAAATAGTGATCTGATCCATAGTATCCTATGCCTA TACACTTTAAAATGTATATACATTTTAGACAAAAATGCACACTCCAGTATTAATATTTGTGCTACCATCTACTTGGAGAAGTTTAATGAG AAAATTTTAGAAGAAAAGTATTACAAACAATATTTTGACTCTATTACCTGTTTTGCCTTATACATTTTAGAAACTGGAAATTTTTTAAAG AAAATGCTTTAGTTTTCTTCTGTTCTTCACTGTCTACAGTGTGCTTTTGTATATGGATCAGGACTGAGCAAAGTAATTACATGTATCAGA GATACTTATCTCTATACTAATTCACAGACAGCTCCTGATGTAAGGATTTAGAGGGCCTTCTGCCCTCTGAATATATGGTGAGGAGAATGG GGTATCTGGAAAAGGAAAATGATCTGGATAAATCTGAGACCTGGGGGGAAGTTTGTTTTATATGTTCATTATTGGTTGTTACATATCAAG GCTGTTTTGGTTATGTATCAATATTGTGGTTTATTTGAGCTGGAAGTGATTTTTTCTGTGTATGTATATGTATACACTTCAATAGGTTTT AATTTTGAAGTGAATATTTGCCATGACTCCATTTTCCCCATACCACTTCAGACTTTAGCCTGTTTAGTTTTAAGGACTGAAAATGGTAGG TTTGGGCAGAAGAATGAATTTGAACTTTGATGGGGTTTTTTTGTTTTTACTTTCTATCTTCATAACCATTTAAAGCGATTTAGCTTGAAA TTAAATTTTATCAGGCTACCAACATGTTATTTATTTATTTAATAAACACATTTATTGAAAACCTATACTATTGTATTGGCACCATACAGG GTATTGTATTTATACTAGTGAGCAGACCAGGGCATTTCCATCCTCATGGAGTTCATGGTCTAATGAAAATAGCTGGGGCCGGGTGTGGTG GCTCACCCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGTTTGAGCCCAGGAGTTTGAGACCAGCCAGGGCAACATGGCA AAACCCCATGTGTACAAAAGATTAAAAAATTAGCCAGATGCAGTGGCACATGGCTGGGGTCCCAGCTACCCAGGAGGCTGAGTTGGGAGG ATCATCTGAGCCTGGGAGGTTGAAGCTTGCAGTGAGCTATGATTGCCACTGTACTCTATACTCCAGCCTGGGTGACAGAGTGAAACCCTG TCTCAAAAAAAAAAGAGGAAAGAAAATAGCTAGGAGACAATCAGAGCAGATCTTGGGCTTCTGTGGCTCATCTCAGCCCTTTATAACTGG CCTGAGAAGAGGGTTTATCTACTTGTGCAAGTGGCCCAGAAATCTCACTCGTACATGAGGCTTTGGAACATCCTTGCAAAGGTACGCTGA AAGCAAATTGCTGTTTTCCTGGTGGTTCTGCACGTTTCCTAACTTTTATCATAGTTTGATTTTCATTATTTAAGAAAAAATAAAAAATCC AAAGACCATAAGATGGCATTAGATTTTTTACCATTAAATTATTAATGCCTATTTGGTGCTCATAAAGATTAATCATGTCACGCATGTTTC CAATCTTTCTTTTGCAGTATATTATTTTCTAAAAATTGTTACATGCAAATTTAAACCAAGATTTATCAGTAAAAGAAAAAAATAGAATCC TTAATAATGTAAATGTTGTTATATATGCTACCCTGGTGAAAATATTTTTATAAATCATGTTGTCATTTATGCTTTATGTAGCCTATTTTT CAATAACCTTTTTTTAAAAGCAATTTTTTTTGACACCAAGATTGTTGATTTTTAATTAACACCAGTTGGTGGCACTAGAAACCTGAAATT TTTCAAAGATGAACAAAGAAAAATTGAAAAGGTAATCTAAACATGGAGAATTTTTAGGAAAATAAATGAAAAATATAATTGTATATTAGA GATGTATTTTTCTTCTGGAATGGAATTCTTTTTCTAAAATGCAAATCGCTATCCATTTTGACTGCAATGATGAAACTTGTTTATCTTCCA GAGGACATATATATATGTGTGTGTGTGTGTATTGTACAGATACCTTTAATTTGATTACACTGTTTCTTGTAAATATGTTTCTGTATAAAA >30278_30278_1_FGFR2-C10orf118_FGFR2_chr10_123243212_ENST00000346997_C10orf118_chr10_115910979_ENST00000369287_length(amino acids)=1410AA_BP=765 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGE YLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCP AGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVL PAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLS STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIG KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRM DKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNELESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQAN KKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSH VIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHH AKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLN SLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAE LACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARSSAEDRSPENTGSSV AVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSH -------------------------------------------------------------- >30278_30278_2_FGFR2-C10orf118_FGFR2_chr10_123243212_ENST00000369056_C10orf118_chr10_115910979_ENST00000369287_length(transcript)=8547nt_BP=2328nt GGACCGGGGATTGGTACCGTAACCATGGTCAGCTGGGGTCGTTTCATCTGCCTGGTCGTGGTCACCATGGCAACCTTGTCCCTGGCCCGG CCCTCCTTCAGTTTAGTTGAGGATACCACATTAGAGCCAGAAGAGCCACCAACCAAATACCAAATCTCTCAACCAGAAGTGTACGTGGCT GCGCCAGGGGAGTCGCTAGAGGTGCGCTGCCTGTTGAAAGATGCCGCCGTGATCAGTTGGACTAAGGATGGGGTGCACTTGGGGCCCAAC AATAGGACAGTGCTTATTGGGGAGTACTTGCAGATAAAGGGCGCCACGCCTAGAGACTCCGGCCTCTATGCTTGTACTGCCAGTAGGACT GTAGACAGTGAAACTTGGTACTTCATGGTGAATGTCACAGATGCCATCTCATCCGGAGATGATGAGGATGACACCGATGGTGCGGAAGAT TTTGTCAGTGAGAACAGTAACAACAAGAGAGCACCATACTGGACCAACACAGAAAAGATGGAAAAGCGGCTCCATGCTGTGCCTGCGGCC AACACTGTCAAGTTTCGCTGCCCAGCCGGGGGGAACCCAATGCCAACCATGCGGTGGCTGAAAAACGGGAAGGAGTTTAAGCAGGAGCAT CGCATTGGAGGCTACAAGGTACGAAACCAGCACTGGAGCCTCATTATGGAAAGTGTGGTCCCATCTGACAAGGGAAATTATACCTGTGTA GTGGAGAATGAATACGGGTCCATCAATCACACGTACCACCTGGATGTTGTGGAGCGATCGCCTCACCGGCCCATCCTCCAAGCCGGACTG CCGGCAAATGCCTCCACAGTGGTCGGAGGAGACGTAGAGTTTGTCTGCAAGGTTTACAGTGATGCCCAGCCCCACATCCAGTGGATCAAG CACGTGGAAAAGAACGGCAGTAAATACGGGCCCGACGGGCTGCCCTACCTCAAGGTTCTCAAGCACTCGGGGATAAATAGTTCCAATGCA GAAGTGCTGGCTCTGTTCAATGTGACCGAGGCGGATGCTGGGGAATATATATGTAAGGTCTCCAATTATATAGGGCAGGCCAACCAGTCT GCCTGGCTCACTGTCCTGCCAAAACAGCAAGCGCCTGGAAGAGAAAAGGAGATTACAGCTTCCCCAGACTACCTGGAGATAGCCATTTAC TGCATAGGGGTCTTCTTAATCGCCTGTATGGTGGTAACAGTCATCCTGTGCCGAATGAAGAACACGACCAAGAAGCCAGACTTCAGCAGC CAGCCGGCTGTGCACAAGCTGACCAAACGTATCCCCCTGCGGAGACAGGTAACAGTTTCGGCTGAGTCCAGCTCCTCCATGAACTCCAAC ACCCCGCTGGTGAGGATAACAACACGCCTCTCTTCAACGGCAGACACCCCCATGCTGGCAGGGGTCTCCGAGTATGAACTTCCAGAGGAC CCAAAATGGGAGTTTCCAAGAGATAAGCTGACACTGGGCAAGCCCCTGGGAGAAGGTTGCTTTGGGCAAGTGGTCATGGCGGAAGCAGTG GGAATTGACAAAGACAAGCCCAAGGAGGCGGTCACCGTGGCCGTGAAGATGTTGAAAGATGATGCCACAGAGAAAGACCTTTCTGATCTG GTGTCAGAGATGGAGATGATGAAGATGATTGGGAAACACAAGAATATCATAAATCTTCTTGGAGCCTGCACACAGGATGGGCCTCTCTAT GTCATAGTTGAGTATGCCTCTAAAGGCAACCTCCGAGAATACCTCCGAGCCCGGAGGCCACCCGGGATGGAGTACTCCTATGACATTAAC CGTGTTCCTGAGGAGCAGATGACCTTCAAGGACTTGGTGTCATGCACCTACCAGCTGGCCAGAGGCATGGAGTACTTGGCTTCCCAAAAA TGTATTCATCGAGATTTAGCAGCCAGAAATGTTTTGGTAACAGAAAACAATGTGATGAAAATAGCAGACTTTGGACTCGCCAGAGATATC AACAATATAGACTATTACAAAAAGACCACCAATGGGCGGCTTCCAGTCAAGTGGATGGCTCCAGAAGCCCTGTTTGATAGAGTATACACT CATCAGAGTGATGTCTGGTCCTTCGGGGTGTTAATGTGGGAGATCTTCACTTTAGGGGGCTCGCCCTACCCAGGGATTCCCGTGGAGGAA CTTTTTAAGCTGCTGAAGGAAGGACACAGAATGGATAAGCCAGCCAACTGCACCAACGAACTGTACATGATGATGAGGGACTGTTGGCAT GCAGTGCCCTCCCAGAGACCAACGTTCAAGCAGTTGGTAGAAGACTTGGATCGAATTCTCACTCTCACAACCAATGAGTTAGAATCAAGA ATAGAAGAACTTAATAAAGAAGTTAAAGCTTCCAGAGATCAACTAATAGCTCAAGACGTTACAGCTAAAAATGCAGTTCAGCAGTTACAC AAAGAGATGGCCCAACGGATGGAACAGGCCAACAAGAAATGTGAAGAGGCACGCCAAGAAAAAGAAGCAATGGTAATGAAATATGTAAGA GGTGAGAAGGAATCTTTAGATCTTCGAAAGGAAAAAGAGACACTTGAGAAAAAACTTAGAGATGCAAATAAGGAACTTGAGAAAAACACT AACAAAATTAAGCAGCTTTCTCAGGAGAAAGGACGGTTGCACCAGCTGTATGAAACTAAGGAAGGCGAAACGACTAGACTCATCAGAGAA ATAGACAAATTAAAGGAAGACATTAACTCTCACGTCATCAAAGTAAAGTGGGCACAAAACAAATTAAAAGCTGAAATGGATTCACACAAG GAAACCAAAGATAAACTCAAAGAAACAACAACAAAATTAACACAAGCAAAGGAAGAAGCAGATCAGATACGAAAAAACTGTCAGGATATG ATAAAAACATATCAGGAGTCAGAAGAAATTAAATCAAATGAGCTTGATGCAAAGCTTAGAGTCACAAAAGGAGAACTTGAAAAACAAATG CAAGAAAAATCTGACCAGCTAGAGATGCATCATGCCAAAATAAAGGAACTAGAAGATCTGAAGAGAACATTTAAGGAGGGTATGGATGAG TTAAGAACACTGAGAACAAAGGTGAAATGTCTAGAAGATGAACGATTAAGAACAGAAGATGAATTATCAAAATATAAGGAAATTATTAAT CGCCAAAAAGCTGAAATTCAGAATTTATTGGACAAGGTGAAAACTGCAGATCAGCTACAGGAGCAGCTTCAAAGAGGTAAGCAAGAAATT GAAAATTTGAAAGAAGAAGTGGAAAGTCTTAATTCTTTGATTAATGACCTACAAAAAGACATCGAAGGCAGTAGGAAAAGAGAATCTGAG CTGCTGCTGTTTACAGAAAGGCTCACTAGTAAGAATGCACAGCTTCAGTCTGAATCCAATTCTTTGCAGTCACAATTTGATAAAGTTTCC TGTAGTGAAAGTCAGTTACAAAGCCAGTGTGAACAAATGAAACAGACAAATATTAATTTGGAAAGTAGGTTGTTGAAAGAGGAAGAACTG CGAAAAGAGGAAGTCCAAACTCTGCAAGCTGAACTCGCTTGTAGACAAACAGAAGTTAAAGCATTGAGTACCCAGGTAGAAGAATTAAAA GATGAGTTAGTAACTCAGAGACGTAAACATGCCTCTAGTATCAAGGATCTCACCAAACAACTTCAGCAAGCACGAAGAAAATTAGATCAG GTTGAGAGTGGAAGCTATGACAAAGAAGTCAGCAGCATGGGAAGTCGTTCTAGTTCATCAGGGTCCCTGAATGCTCGAAGCAGTGCAGAA GATCGATCTCCAGAAAATACTGGGTCCTCAGTAGCTGTGGATAACTTTCCACAAGTAGATAAGGCCATGTTGATTGAGAGAATAGTTAGG CTGCAAAAAGCACATGCCCGGAAAAATGAAAAGATAGAATTTATGGAGGACCACATCAAACAACTGGTGGAAGAAATTAGGAAAAAAACA AAAATAATTCAAAGTTATATTTTACGAGAAGAATCAGGCACACTTTCTTCAGAGGCATCTGATTTTAACAAAGTTCATTTAAGTAGACGG GGTGGCATCATGGCATCTTTATATACATCCCATCCAGCTGACAATGGATTAACATTGGAGCTCTCTTTGGAAATCAACCGAAAATTACAG GCTGTTTTGGAGGATACGTTACTAAAAAATATTACTTTGAAGGAAAATCTACAAACACTTGGAACAGAAATAGAACGTCTTATTAAACAC CAGCATGAACTAGAACAGAGGACAAAGAAAACCTAAAACAAGCCTCTTGCTCAGTAAAGAGACAAAAGCCACACAGGAGTAGGTGCCACT GACCTCTATTGTTGGAGACTTTGTTCCACTTTTTGTTTCAGCCAGTAAAAATATTGTTTTGCTTCATCTGTACACAAAAAAATACCCTTT TACAATATGAATGCATTGCTGTATATACTGTAAGACTGAAAGCTTTGATGAAATTTGTTTTTGTATGGTGCAATATGACAGCCTGTCATT GAATCTAAACAACTTAATTTGCTTGTATTCATAAGAAGTGTTGAACATTACAAGGGCTTTTATAAAAAACCCTTTGTTCATATTTCTTCC CTTTAAAATATGTAATGTCAAAAATGACTCACCTTTTAAAAATTATGCATGAAAACAGGTGGTAAACATTCAGTAATACGCTATTTCTCC AACATCAAGACAACTAAAACAAATGATAAAAATGTTTATTTTTACACTCCAGCATATCGGGTGAGTTTTAGGGATGTGTATGAATATTTA AATCTTTTAATTTCAGTTTTAATGAAAGCTGAACTTAATAGGAAAGCTAGCTCTTGGTAACTAGCAATGATCAGGCATTGTTTGCCTCTG TCAGGTTTTCTTATCTGTTTTAGGTACATTTTTTCAGATTCTGATTGTTTGAGTTAATGGTTGAATTTTTAAAGTTTTTAGTTACTTAAA ATATGATTTTAAATTACATATTAATTTAGAAAATTCCTGTGTTTACTTATATTTTAAATTGTGAAATGGATCCAATCATTAGAACAGAGA GAATAGTTCTTTGAAACTGAAATACTTTAGTTTTACTGACCTTGTGTAAAGATAATATGAAGAACCAGCTTCCAAAAGAAACCAGCATAT GGCACTATAAACTATTTCATTTGAGCACCATTCTTTACCATGGATATATTAATTATGTATTATAGTGGAGTGATCATACAGTTCCCCCAA ATGTGATGTTTCAGTGTATTTATTTAAAACATAAAGTAGACCAGGTGCAGTAGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGG CAGGAGGATTACCTGAGGCCAGGAGTTTAAGACCAGCCTTGGCAACATAGCGAGACCCCCATCTCTACAAAGAAATTTTAAAAGATTATC CAGGCATGGTGGTGCATGCCTATGGTTCCAGCTACTCGGGAGGCTGAAGCGGTAGAATCACTTGAGCACAGGAGGTCAAGGCTGCAGGTG AGCCATGATCGTGTCACTGCACTCCAGCCTAGGCAACAGAGCAAGACCCTGTCTCTTAAAACAAAAAACCTCACACATACCTAAAATAAG TATATATCTGTAACCAAAGGAACTTAATTTTAGAGCCAAATTTTTCTATCTTGTTGGATTTTTTACAGTGTTTAAGATAGACACTTAAGT GTTGCCGTAGTATCAATATTTCTGTCATTGAATTTTTTCTCACCCCTTATTATTTCTCACTTACAATTTCTGAGCATGATTTTTCATAAT TCATTATCTTCAGATCATTACTATAATAAGATACCGTGGCTCTTATGCAGATATTGCAGCAAGCCTTGTTTGGTTTGGATTTTTGCATCC CTTTTTCTCCCATTAAGGGAATTAAGTTTTGGGATGATGGATTAAAAGCCTGTAAAGAATTGTTTGGGCTCTAAAAGTTGGGCTCATGGT GGCAATATCCTTTTAATGTGTTTTAACATTTTTTAATCAACATCGTTTAAAAATAATTTACTAAGGATTAGATTATTTAATGAATGTCTT TTTTTCTATATATTGAATTAGATGTTATCCCAAAAAAAATATCTTTTCACTTCAAAATGAAAATATATGTTCAAAGATGTTTTATTTTTA GAATAGTTATAAAAAGTATTAGTCTTAACATAATGTGTCTTGTTCTTTTTACCAATAATAATTTATCAAAATAAGAGGGAAAGTGCAATC AAATCTGAATTATTTTACTATTTGTTTCTAGACACACTACTTAACACTCCTAAAGACTACTTTGAGTAGGCAACATAACTAAATTTTTCT AGTTTCTTATGATACAGGTTCATAAACTACAATATTTGGATTTTTTTCCCCAAGGCACAAAATGTATAATGGAGACCAAATAGTGATCTG ATCCATAGTATCCTATGCCTATACACTTTAAAATGTATATACATTTTAGACAAAAATGCACACTCCAGTATTAATATTTGTGCTACCATC TACTTGGAGAAGTTTAATGAGAAAATTTTAGAAGAAAAGTATTACAAACAATATTTTGACTCTATTACCTGTTTTGCCTTATACATTTTA GAAACTGGAAATTTTTTAAAGAAAATGCTTTAGTTTTCTTCTGTTCTTCACTGTCTACAGTGTGCTTTTGTATATGGATCAGGACTGAGC AAAGTAATTACATGTATCAGAGATACTTATCTCTATACTAATTCACAGACAGCTCCTGATGTAAGGATTTAGAGGGCCTTCTGCCCTCTG AATATATGGTGAGGAGAATGGGGTATCTGGAAAAGGAAAATGATCTGGATAAATCTGAGACCTGGGGGGAAGTTTGTTTTATATGTTCAT TATTGGTTGTTACATATCAAGGCTGTTTTGGTTATGTATCAATATTGTGGTTTATTTGAGCTGGAAGTGATTTTTTCTGTGTATGTATAT GTATACACTTCAATAGGTTTTAATTTTGAAGTGAATATTTGCCATGACTCCATTTTCCCCATACCACTTCAGACTTTAGCCTGTTTAGTT TTAAGGACTGAAAATGGTAGGTTTGGGCAGAAGAATGAATTTGAACTTTGATGGGGTTTTTTTGTTTTTACTTTCTATCTTCATAACCAT TTAAAGCGATTTAGCTTGAAATTAAATTTTATCAGGCTACCAACATGTTATTTATTTATTTAATAAACACATTTATTGAAAACCTATACT ATTGTATTGGCACCATACAGGGTATTGTATTTATACTAGTGAGCAGACCAGGGCATTTCCATCCTCATGGAGTTCATGGTCTAATGAAAA TAGCTGGGGCCGGGTGTGGTGGCTCACCCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGTTTGAGCCCAGGAGTTTGAG ACCAGCCAGGGCAACATGGCAAAACCCCATGTGTACAAAAGATTAAAAAATTAGCCAGATGCAGTGGCACATGGCTGGGGTCCCAGCTAC CCAGGAGGCTGAGTTGGGAGGATCATCTGAGCCTGGGAGGTTGAAGCTTGCAGTGAGCTATGATTGCCACTGTACTCTATACTCCAGCCT GGGTGACAGAGTGAAACCCTGTCTCAAAAAAAAAAGAGGAAAGAAAATAGCTAGGAGACAATCAGAGCAGATCTTGGGCTTCTGTGGCTC ATCTCAGCCCTTTATAACTGGCCTGAGAAGAGGGTTTATCTACTTGTGCAAGTGGCCCAGAAATCTCACTCGTACATGAGGCTTTGGAAC ATCCTTGCAAAGGTACGCTGAAAGCAAATTGCTGTTTTCCTGGTGGTTCTGCACGTTTCCTAACTTTTATCATAGTTTGATTTTCATTAT TTAAGAAAAAATAAAAAATCCAAAGACCATAAGATGGCATTAGATTTTTTACCATTAAATTATTAATGCCTATTTGGTGCTCATAAAGAT TAATCATGTCACGCATGTTTCCAATCTTTCTTTTGCAGTATATTATTTTCTAAAAATTGTTACATGCAAATTTAAACCAAGATTTATCAG TAAAAGAAAAAAATAGAATCCTTAATAATGTAAATGTTGTTATATATGCTACCCTGGTGAAAATATTTTTATAAATCATGTTGTCATTTA TGCTTTATGTAGCCTATTTTTCAATAACCTTTTTTTAAAAGCAATTTTTTTTGACACCAAGATTGTTGATTTTTAATTAACACCAGTTGG TGGCACTAGAAACCTGAAATTTTTCAAAGATGAACAAAGAAAAATTGAAAAGGTAATCTAAACATGGAGAATTTTTAGGAAAATAAATGA AAAATATAATTGTATATTAGAGATGTATTTTTCTTCTGGAATGGAATTCTTTTTCTAAAATGCAAATCGCTATCCATTTTGACTGCAATG ATGAAACTTGTTTATCTTCCAGAGGACATATATATATGTGTGTGTGTGTGTATTGTACAGATACCTTTAATTTGATTACACTGTTTCTTG >30278_30278_2_FGFR2-C10orf118_FGFR2_chr10_123243212_ENST00000369056_C10orf118_chr10_115910979_ENST00000369287_length(amino acids)=1413AA_BP=768 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGE YLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCP AGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK QQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITT RLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMK MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAA RNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEG HRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNELESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRME QANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDI NSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLE MHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVE SLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTL QAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARSSAEDRSPENTG SSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLY -------------------------------------------------------------- >30278_30278_3_FGFR2-C10orf118_FGFR2_chr10_123243212_ENST00000369061_C10orf118_chr10_115910979_ENST00000369287_length(transcript)=8334nt_BP=2115nt TGACTGCAGCAGCAGCGGCAGCGCCTCGGTTCCTGAGCCCACCGCAGGCTGAAGGCATTGCGCGTAGTCCATGCCCGTAGAGGAAGTGTG CAGATGGGATTAACGTCCACATGGAGATATGGAAGAGGACCGGGGATTGGTACCGTAACCATGGTCAGCTGGGGTCGTTTCATCTGCCTG GTCGTGGTCACCATGGCAACCTTGTCCCTGGCCCGGCCCTCCTTCAGTTTAGTTGAGGATACCACATTAGAGCCAGAAGAGCCACCAACC AAATACCAAATCTCTCAACCAGAAGTGTACGTGGCTGCGCCAGGGGAGTCGCTAGAGGTGCGCTGCCTGTTGAAAGATGCCGCCGTGATC AGTTGGACTAAGGATGGGGTGCACTTGGGGCCCAACAATAGGACAGTGCTTATTGGGGAGTACTTGCAGATAAAGGGCGCCACGCCTAGA GACTCCGGCCTCTATGCTTGTACTGCCAGTAGGACTGTAGACAGTGAAACTTGGTACTTCATGGTGAATGTCACAGATGCCATCTCATCC GGAGATGATGAGGATGACACCGATGGTGCGGAAGATTTTGTCAGTGAGAACAGTAACAACAAGAGAGCACCATACTGGACCAACACAGAA AAGATGGAAAAGCGGCTCCATGCTGTGCCTGCGGCCAACACTGTCAAGTTTCGCTGCCCAGCCGGGGGGAACCCAATGCCAACCATGCGG TGGCTGAAAAACGGGAAGGAGTTTAAGCAGGAGCATCGCATTGGAGGCTACAAGGTACGAAACCAGCACTGGAGCCTCATTATGGAAAGT GTGGTCCCATCTGACAAGGGAAATTATACCTGTGTAGTGGAGAATGAATACGGGTCCATCAATCACACGTACCACCTGGATGTTGTGGCG CCTGGAAGAGAAAAGGAGATTACAGCTTCCCCAGACTACCTGGAGATAGCCATTTACTGCATAGGGGTCTTCTTAATCGCCTGTATGGTG GTAACAGTCATCCTGTGCCGAATGAAGAACACGACCAAGAAGCCAGACTTCAGCAGCCAGCCGGCTGTGCACAAGCTGACCAAACGTATC CCCCTGCGGAGACAGGTAACAGTTTCGGCTGAGTCCAGCTCCTCCATGAACTCCAACACCCCGCTGGTGAGGATAACAACACGCCTCTCT TCAACGGCAGACACCCCCATGCTGGCAGGGGTCTCCGAGTATGAACTTCCAGAGGACCCAAAATGGGAGTTTCCAAGAGATAAGCTGACA CTGGGCAAGCCCCTGGGAGAAGGTTGCTTTGGGCAAGTGGTCATGGCGGAAGCAGTGGGAATTGACAAAGACAAGCCCAAGGAGGCGGTC ACCGTGGCCGTGAAGATGTTGAAAGATGATGCCACAGAGAAAGACCTTTCTGATCTGGTGTCAGAGATGGAGATGATGAAGATGATTGGG AAACACAAGAATATCATAAATCTTCTTGGAGCCTGCACACAGGATGGGCCTCTCTATGTCATAGTTGAGTATGCCTCTAAAGGCAACCTC CGAGAATACCTCCGAGCCCGGAGGCCACCCGGGATGGAGTACTCCTATGACATTAACCGTGTTCCTGAGGAGCAGATGACCTTCAAGGAC TTGGTGTCATGCACCTACCAGCTGGCCAGAGGCATGGAGTACTTGGCTTCCCAAAAATGTATTCATCGAGATTTAGCAGCCAGAAATGTT TTGGTAACAGAAAACAATGTGATGAAAATAGCAGACTTTGGACTCGCCAGAGATATCAACAATATAGACTATTACAAAAAGACCACCAAT GGGCGGCTTCCAGTCAAGTGGATGGCTCCAGAAGCCCTGTTTGATAGAGTATACACTCATCAGAGTGATGTCTGGTCCTTCGGGGTGTTA ATGTGGGAGATCTTCACTTTAGGGGGCTCGCCCTACCCAGGGATTCCCGTGGAGGAACTTTTTAAGCTGCTGAAGGAAGGACACAGAATG GATAAGCCAGCCAACTGCACCAACGAACTGTACATGATGATGAGGGACTGTTGGCATGCAGTGCCCTCCCAGAGACCAACGTTCAAGCAG TTGGTAGAAGACTTGGATCGAATTCTCACTCTCACAACCAATGAGTTAGAATCAAGAATAGAAGAACTTAATAAAGAAGTTAAAGCTTCC AGAGATCAACTAATAGCTCAAGACGTTACAGCTAAAAATGCAGTTCAGCAGTTACACAAAGAGATGGCCCAACGGATGGAACAGGCCAAC AAGAAATGTGAAGAGGCACGCCAAGAAAAAGAAGCAATGGTAATGAAATATGTAAGAGGTGAGAAGGAATCTTTAGATCTTCGAAAGGAA AAAGAGACACTTGAGAAAAAACTTAGAGATGCAAATAAGGAACTTGAGAAAAACACTAACAAAATTAAGCAGCTTTCTCAGGAGAAAGGA CGGTTGCACCAGCTGTATGAAACTAAGGAAGGCGAAACGACTAGACTCATCAGAGAAATAGACAAATTAAAGGAAGACATTAACTCTCAC GTCATCAAAGTAAAGTGGGCACAAAACAAATTAAAAGCTGAAATGGATTCACACAAGGAAACCAAAGATAAACTCAAAGAAACAACAACA AAATTAACACAAGCAAAGGAAGAAGCAGATCAGATACGAAAAAACTGTCAGGATATGATAAAAACATATCAGGAGTCAGAAGAAATTAAA TCAAATGAGCTTGATGCAAAGCTTAGAGTCACAAAAGGAGAACTTGAAAAACAAATGCAAGAAAAATCTGACCAGCTAGAGATGCATCAT GCCAAAATAAAGGAACTAGAAGATCTGAAGAGAACATTTAAGGAGGGTATGGATGAGTTAAGAACACTGAGAACAAAGGTGAAATGTCTA GAAGATGAACGATTAAGAACAGAAGATGAATTATCAAAATATAAGGAAATTATTAATCGCCAAAAAGCTGAAATTCAGAATTTATTGGAC AAGGTGAAAACTGCAGATCAGCTACAGGAGCAGCTTCAAAGAGGTAAGCAAGAAATTGAAAATTTGAAAGAAGAAGTGGAAAGTCTTAAT TCTTTGATTAATGACCTACAAAAAGACATCGAAGGCAGTAGGAAAAGAGAATCTGAGCTGCTGCTGTTTACAGAAAGGCTCACTAGTAAG AATGCACAGCTTCAGTCTGAATCCAATTCTTTGCAGTCACAATTTGATAAAGTTTCCTGTAGTGAAAGTCAGTTACAAAGCCAGTGTGAA CAAATGAAACAGACAAATATTAATTTGGAAAGTAGGTTGTTGAAAGAGGAAGAACTGCGAAAAGAGGAAGTCCAAACTCTGCAAGCTGAA CTCGCTTGTAGACAAACAGAAGTTAAAGCATTGAGTACCCAGGTAGAAGAATTAAAAGATGAGTTAGTAACTCAGAGACGTAAACATGCC TCTAGTATCAAGGATCTCACCAAACAACTTCAGCAAGCACGAAGAAAATTAGATCAGGTTGAGAGTGGAAGCTATGACAAAGAAGTCAGC AGCATGGGAAGTCGTTCTAGTTCATCAGGGTCCCTGAATGCTCGAAGCAGTGCAGAAGATCGATCTCCAGAAAATACTGGGTCCTCAGTA GCTGTGGATAACTTTCCACAAGTAGATAAGGCCATGTTGATTGAGAGAATAGTTAGGCTGCAAAAAGCACATGCCCGGAAAAATGAAAAG ATAGAATTTATGGAGGACCACATCAAACAACTGGTGGAAGAAATTAGGAAAAAAACAAAAATAATTCAAAGTTATATTTTACGAGAAGAA TCAGGCACACTTTCTTCAGAGGCATCTGATTTTAACAAAGTTCATTTAAGTAGACGGGGTGGCATCATGGCATCTTTATATACATCCCAT CCAGCTGACAATGGATTAACATTGGAGCTCTCTTTGGAAATCAACCGAAAATTACAGGCTGTTTTGGAGGATACGTTACTAAAAAATATT ACTTTGAAGGAAAATCTACAAACACTTGGAACAGAAATAGAACGTCTTATTAAACACCAGCATGAACTAGAACAGAGGACAAAGAAAACC TAAAACAAGCCTCTTGCTCAGTAAAGAGACAAAAGCCACACAGGAGTAGGTGCCACTGACCTCTATTGTTGGAGACTTTGTTCCACTTTT TGTTTCAGCCAGTAAAAATATTGTTTTGCTTCATCTGTACACAAAAAAATACCCTTTTACAATATGAATGCATTGCTGTATATACTGTAA GACTGAAAGCTTTGATGAAATTTGTTTTTGTATGGTGCAATATGACAGCCTGTCATTGAATCTAAACAACTTAATTTGCTTGTATTCATA AGAAGTGTTGAACATTACAAGGGCTTTTATAAAAAACCCTTTGTTCATATTTCTTCCCTTTAAAATATGTAATGTCAAAAATGACTCACC TTTTAAAAATTATGCATGAAAACAGGTGGTAAACATTCAGTAATACGCTATTTCTCCAACATCAAGACAACTAAAACAAATGATAAAAAT GTTTATTTTTACACTCCAGCATATCGGGTGAGTTTTAGGGATGTGTATGAATATTTAAATCTTTTAATTTCAGTTTTAATGAAAGCTGAA CTTAATAGGAAAGCTAGCTCTTGGTAACTAGCAATGATCAGGCATTGTTTGCCTCTGTCAGGTTTTCTTATCTGTTTTAGGTACATTTTT TCAGATTCTGATTGTTTGAGTTAATGGTTGAATTTTTAAAGTTTTTAGTTACTTAAAATATGATTTTAAATTACATATTAATTTAGAAAA TTCCTGTGTTTACTTATATTTTAAATTGTGAAATGGATCCAATCATTAGAACAGAGAGAATAGTTCTTTGAAACTGAAATACTTTAGTTT TACTGACCTTGTGTAAAGATAATATGAAGAACCAGCTTCCAAAAGAAACCAGCATATGGCACTATAAACTATTTCATTTGAGCACCATTC TTTACCATGGATATATTAATTATGTATTATAGTGGAGTGATCATACAGTTCCCCCAAATGTGATGTTTCAGTGTATTTATTTAAAACATA AAGTAGACCAGGTGCAGTAGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGCAGGAGGATTACCTGAGGCCAGGAGTTTAAGAC CAGCCTTGGCAACATAGCGAGACCCCCATCTCTACAAAGAAATTTTAAAAGATTATCCAGGCATGGTGGTGCATGCCTATGGTTCCAGCT ACTCGGGAGGCTGAAGCGGTAGAATCACTTGAGCACAGGAGGTCAAGGCTGCAGGTGAGCCATGATCGTGTCACTGCACTCCAGCCTAGG CAACAGAGCAAGACCCTGTCTCTTAAAACAAAAAACCTCACACATACCTAAAATAAGTATATATCTGTAACCAAAGGAACTTAATTTTAG AGCCAAATTTTTCTATCTTGTTGGATTTTTTACAGTGTTTAAGATAGACACTTAAGTGTTGCCGTAGTATCAATATTTCTGTCATTGAAT TTTTTCTCACCCCTTATTATTTCTCACTTACAATTTCTGAGCATGATTTTTCATAATTCATTATCTTCAGATCATTACTATAATAAGATA CCGTGGCTCTTATGCAGATATTGCAGCAAGCCTTGTTTGGTTTGGATTTTTGCATCCCTTTTTCTCCCATTAAGGGAATTAAGTTTTGGG ATGATGGATTAAAAGCCTGTAAAGAATTGTTTGGGCTCTAAAAGTTGGGCTCATGGTGGCAATATCCTTTTAATGTGTTTTAACATTTTT TAATCAACATCGTTTAAAAATAATTTACTAAGGATTAGATTATTTAATGAATGTCTTTTTTTCTATATATTGAATTAGATGTTATCCCAA AAAAAATATCTTTTCACTTCAAAATGAAAATATATGTTCAAAGATGTTTTATTTTTAGAATAGTTATAAAAAGTATTAGTCTTAACATAA TGTGTCTTGTTCTTTTTACCAATAATAATTTATCAAAATAAGAGGGAAAGTGCAATCAAATCTGAATTATTTTACTATTTGTTTCTAGAC ACACTACTTAACACTCCTAAAGACTACTTTGAGTAGGCAACATAACTAAATTTTTCTAGTTTCTTATGATACAGGTTCATAAACTACAAT ATTTGGATTTTTTTCCCCAAGGCACAAAATGTATAATGGAGACCAAATAGTGATCTGATCCATAGTATCCTATGCCTATACACTTTAAAA TGTATATACATTTTAGACAAAAATGCACACTCCAGTATTAATATTTGTGCTACCATCTACTTGGAGAAGTTTAATGAGAAAATTTTAGAA GAAAAGTATTACAAACAATATTTTGACTCTATTACCTGTTTTGCCTTATACATTTTAGAAACTGGAAATTTTTTAAAGAAAATGCTTTAG TTTTCTTCTGTTCTTCACTGTCTACAGTGTGCTTTTGTATATGGATCAGGACTGAGCAAAGTAATTACATGTATCAGAGATACTTATCTC TATACTAATTCACAGACAGCTCCTGATGTAAGGATTTAGAGGGCCTTCTGCCCTCTGAATATATGGTGAGGAGAATGGGGTATCTGGAAA AGGAAAATGATCTGGATAAATCTGAGACCTGGGGGGAAGTTTGTTTTATATGTTCATTATTGGTTGTTACATATCAAGGCTGTTTTGGTT ATGTATCAATATTGTGGTTTATTTGAGCTGGAAGTGATTTTTTCTGTGTATGTATATGTATACACTTCAATAGGTTTTAATTTTGAAGTG AATATTTGCCATGACTCCATTTTCCCCATACCACTTCAGACTTTAGCCTGTTTAGTTTTAAGGACTGAAAATGGTAGGTTTGGGCAGAAG AATGAATTTGAACTTTGATGGGGTTTTTTTGTTTTTACTTTCTATCTTCATAACCATTTAAAGCGATTTAGCTTGAAATTAAATTTTATC AGGCTACCAACATGTTATTTATTTATTTAATAAACACATTTATTGAAAACCTATACTATTGTATTGGCACCATACAGGGTATTGTATTTA TACTAGTGAGCAGACCAGGGCATTTCCATCCTCATGGAGTTCATGGTCTAATGAAAATAGCTGGGGCCGGGTGTGGTGGCTCACCCCTGT AATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGTTTGAGCCCAGGAGTTTGAGACCAGCCAGGGCAACATGGCAAAACCCCATGTG TACAAAAGATTAAAAAATTAGCCAGATGCAGTGGCACATGGCTGGGGTCCCAGCTACCCAGGAGGCTGAGTTGGGAGGATCATCTGAGCC TGGGAGGTTGAAGCTTGCAGTGAGCTATGATTGCCACTGTACTCTATACTCCAGCCTGGGTGACAGAGTGAAACCCTGTCTCAAAAAAAA AAGAGGAAAGAAAATAGCTAGGAGACAATCAGAGCAGATCTTGGGCTTCTGTGGCTCATCTCAGCCCTTTATAACTGGCCTGAGAAGAGG GTTTATCTACTTGTGCAAGTGGCCCAGAAATCTCACTCGTACATGAGGCTTTGGAACATCCTTGCAAAGGTACGCTGAAAGCAAATTGCT GTTTTCCTGGTGGTTCTGCACGTTTCCTAACTTTTATCATAGTTTGATTTTCATTATTTAAGAAAAAATAAAAAATCCAAAGACCATAAG ATGGCATTAGATTTTTTACCATTAAATTATTAATGCCTATTTGGTGCTCATAAAGATTAATCATGTCACGCATGTTTCCAATCTTTCTTT TGCAGTATATTATTTTCTAAAAATTGTTACATGCAAATTTAAACCAAGATTTATCAGTAAAAGAAAAAAATAGAATCCTTAATAATGTAA ATGTTGTTATATATGCTACCCTGGTGAAAATATTTTTATAAATCATGTTGTCATTTATGCTTTATGTAGCCTATTTTTCAATAACCTTTT TTTAAAAGCAATTTTTTTTGACACCAAGATTGTTGATTTTTAATTAACACCAGTTGGTGGCACTAGAAACCTGAAATTTTTCAAAGATGA ACAAAGAAAAATTGAAAAGGTAATCTAAACATGGAGAATTTTTAGGAAAATAAATGAAAAATATAATTGTATATTAGAGATGTATTTTTC TTCTGGAATGGAATTCTTTTTCTAAAATGCAAATCGCTATCCATTTTGACTGCAATGATGAAACTTGTTTATCTTCCAGAGGACATATAT ATATGTGTGTGTGTGTGTATTGTACAGATACCTTTAATTTGATTACACTGTTTCTTGTAAATATGTTTCTGTATAAAATGAAACTTTTCA >30278_30278_3_FGFR2-C10orf118_FGFR2_chr10_123243212_ENST00000369061_C10orf118_chr10_115910979_ENST00000369287_length(amino acids)=1334AA_BP=689 MKALRVVHARRGSVQMGLTSTWRYGRGPGIGTVTMVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGE SLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSE NSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE YGSINHTYHLDVVAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSM NSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDL SDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLA SQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIP VEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNELESRIEELNKEVKASRDQLIAQDVTAKNAVQ QLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRL IREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELE KQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK QEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKE EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARS SAEDRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for FGFR2-C10orf118 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for FGFR2-C10orf118 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for FGFR2-C10orf118 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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