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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:FKBP9-LANCL2 (FusionGDB2 ID:30541) |
Fusion Gene Summary for FKBP9-LANCL2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FKBP9-LANCL2 | Fusion gene ID: 30541 | Hgene | Tgene | Gene symbol | FKBP9 | LANCL2 | Gene ID | 11328 | 55915 |
| Gene name | FKBP prolyl isomerase 9 | LanC like 2 | |
| Synonyms | FKBP60|FKBP63|PPIase | GPR69B|TASP | |
| Cytomap | 7p14.3 | 7p11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | peptidyl-prolyl cis-trans isomerase FKBP963 kDa FK506-binding protein63 kDa FKBPFK506 binding protein 9, 63 kDaFK506-binding protein 9FKBP-63FKBP-9PPIase FKBP9rotamase | lanC-like protein 2G protein-coupled receptor 69BLanC (bacterial lantibiotic synthetase component C)-like 2LanC lantibiotic synthetase component C-like 2testis-specific adriamycin sensitivity protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | O95302 | Q9NS86 | |
| Ensembl transtripts involved in fusion gene | ENST00000242209, ENST00000490776, ENST00000538336, ENST00000538443, ENST00000489038, | ENST00000486376, ENST00000254770, | |
| Fusion gene scores | * DoF score | 7 X 7 X 4=196 | 12 X 7 X 6=504 |
| # samples | 7 | 11 | |
| ** MAII score | log2(7/196*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/504*10)=-2.19592020997526 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FKBP9 [Title/Abstract] AND LANCL2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | FKBP9(33039872)-LANCL2(55466116), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | LANCL2 | GO:0009789 | positive regulation of abscisic acid-activated signaling pathway | 19667068 |
| Tgene | LANCL2 | GO:0045892 | negative regulation of transcription, DNA-templated | 12566319 |
| Fusion gene breakpoints across FKBP9 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across LANCL2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | GBM | TCGA-19-2624-01A | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
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Fusion Gene ORF analysis for FKBP9-LANCL2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000242209 | ENST00000486376 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| 5CDS-3UTR | ENST00000490776 | ENST00000486376 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| 5CDS-3UTR | ENST00000538336 | ENST00000486376 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| 5CDS-3UTR | ENST00000538443 | ENST00000486376 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| In-frame | ENST00000242209 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| In-frame | ENST00000490776 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| In-frame | ENST00000538336 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| In-frame | ENST00000538443 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| intron-3CDS | ENST00000489038 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| intron-3UTR | ENST00000489038 | ENST00000486376 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000242209 | FKBP9 | chr7 | 33039872 | + | ENST00000254770 | LANCL2 | chr7 | 55466116 | + | 4994 | 1541 | 169 | 2571 | 800 |
| ENST00000538336 | FKBP9 | chr7 | 33039872 | + | ENST00000254770 | LANCL2 | chr7 | 55466116 | + | 5117 | 1664 | 133 | 2694 | 853 |
| ENST00000538443 | FKBP9 | chr7 | 33039872 | + | ENST00000254770 | LANCL2 | chr7 | 55466116 | + | 4779 | 1326 | 365 | 2356 | 663 |
| ENST00000490776 | FKBP9 | chr7 | 33039872 | + | ENST00000254770 | LANCL2 | chr7 | 55466116 | + | 4207 | 754 | 78 | 1784 | 568 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000242209 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + | 0.000179052 | 0.999821 |
| ENST00000538336 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + | 0.000121726 | 0.9998783 |
| ENST00000538443 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + | 0.000281414 | 0.9997186 |
| ENST00000490776 | ENST00000254770 | FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466116 | + | 0.000197084 | 0.9998029 |
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Fusion Genomic Features for FKBP9-LANCL2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466115 | + | 2.67E-09 | 1 |
| FKBP9 | chr7 | 33039872 | + | LANCL2 | chr7 | 55466115 | + | 2.67E-09 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for FKBP9-LANCL2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:33039872/chr7:55466116) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FKBP9 | LANCL2 |
| FUNCTION: PPIases accelerate the folding of proteins during protein synthesis. | FUNCTION: Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. {ECO:0000269|PubMed:19667068}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 166_254 | 457 | 571.0 | Domain | PPIase FKBP-type 2 |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 278_365 | 457 | 571.0 | Domain | PPIase FKBP-type 3 |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 54_142 | 457 | 571.0 | Domain | PPIase FKBP-type 1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 501_513 | 457 | 571.0 | Calcium binding | 1 |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 546_557 | 457 | 571.0 | Calcium binding | 2 |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 389_477 | 457 | 571.0 | Domain | PPIase FKBP-type 4 |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 488_523 | 457 | 571.0 | Domain | EF-hand 1 |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 533_568 | 457 | 571.0 | Domain | EF-hand 2 |
| Hgene | FKBP9 | chr7:33039872 | chr7:55466116 | ENST00000242209 | + | 8 | 10 | 567_570 | 457 | 571.0 | Motif | Prevents secretion from ER |
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Fusion Gene Sequence for FKBP9-LANCL2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >30541_30541_1_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000242209_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=4994nt_BP=1541nt CCCTGGAGCTGCGGCCGGGAGGGCGGGCGGCCGGGGAGACGGGGTGGCGGCTGCAGCCCGGGTAGGGCCAGGAGACCCGGTCCACGTTTG CAAACGCAGCCGAACGCCCAGGCCGACCCGTGCCGCCCGAGCGCCGCGCTGCGTCCGCGCCACTCTTCTCGCCGCCCCGATGGCGTTCCG GGGCTGGAGGCCCCCGCCGCCACCGCTGCTCCTGCTGCTGCTCTGGGTGACCGGGCAGGCAGCGCCCGTGGCGGGCCTGGGCTCCGACGC GGAGCTGCAGATCGAGCGGCGCTTCGTGCCCGACGAGTGCCCGCGCACCGTGCGCAGCGGCGACTTCGTGCGCTACCACTACGTGGGGAC GTTCCCCGACGGCCAGAAGTTCGACTCCAGCTATGACAGAGACTCCACTTTCAATGTGTTTGTGGGAAAAGGACAGCTGATCACAGGGAT GGACCAGGCTCTTGTTGGGATGTGCGTAAACGAGAGACGTTTCGTGAAGATTCCCCCAAAGCTTGCCTACGGAAATGAAGGAGTTTCTGG TGTGATCCCCCCCAATTCAGTGCTTCATTTTGATGTACTTCTGATGGATATTTGGAATTCTGAAGACCAGGTTCAGATTCACACCTATTT CAAGCCCCCGAGTTGCCCTCGGACCATCCAGGTGTCTGATTTTGTGAGGTACCACTACAACGGGACGTTCCTGGACGGAACTCTGTTTGA TTCGAGTCACAATCGCATGAAAACATATGACACGTATGTGGGAATTGGCTGGCTGATTCCTGGAATGGATAAAGGGCTGCTGGGGATGTG TGTGGGTGAGAAGCGCATCATCACCATTCCTCCTTTTCTGGCCTATGGAGAGGATGGAGATGGGAAAGACATTCCCGGTCAGGCATCTCT GGTGTTTGATGTTGCATTATTGGACCTCCATAACCCCAAGGACAGCATTTCCATTGAGAACAAGGTAGTACCTGAAAACTGTGAGCGGAT AAGTCAAAGTGGGGACTTTCTCAGGTATCATTACAATGGCACGCTTCTGGATGGCACCCTCTTTGATTCCAGCTACTCTCGGAACCGCAC GTTTGACACGTACATTGGGCAGGGCTACGTGATTCCTGGGATGGATGAAGGTCTACTTGGTGTTTGCATTGGAGAAAAGCGAAGGATTGT GGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAAGAGGGAATATCCCCGGCTCGGCTGTGCTGGTGTTTGACATCCATGTGATCGACTT CCACAACCCTTCGGACTCCATCAGCATCACCTCCCACTACAAACCCCCTGACTGCTCAGTGCTGAGTAAGAAGGGAGATTACCTCAAATA TCACTACAATGCCTCACTTCTGGATGGGACCCTGCTGGACTCCACGTGGAATTTAGGCAAAACTTACAATATTGTTCTGGGATCTGGGCA AGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGATGTGCGTTGGCGAGAAACGGACAGTGATCATTCCGCCTCACCTGGGCTATGGGGA AGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGTTGTACCGGGTCACATGTGACCAAACCTACCTGCTCCGATCCCTGGATTACGTAAA AAGAACACTTCGGAATCTGAATGGCCGCAGGGTCACCTTCCTCTGTGGGGATGCTGGCCCCCTGGCTGTTGGAGCTGTGATTTATCACAA ACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCACAAAACTTTTGCAGCTCCAGAGATCGGTTGTCTGCCAAGAATCAGACCTTCCTGA TGAGCTGCTTTATGGACGGGCAGGTTATCTGTATGCCTTACTGTACCTGAACACAGAGATAGGTCCAGGCACCGTGTGTGAGTCAGCTAT TAAAGAGGTAGTCAATGCTATTATTGAATCGGGTAAGACTTTGTCAAGGGAAGAAAGAAAAACGGAGCGCTGCCCGCTGTTGTACCAGTG GCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCATGGCTGGAATTTACTATATGTTAATGCAGCCGGCAGCAAAAGTGGACCAAGAAAC CTTGACAGAAATGGTGAAACCCAGTATTGATTATGTGCGCCACAAAAAATTCCGATCTGGGAATTACCCATCATCATTAAGCAATGAAAC AGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGGGGGTCATCCACATGCTCATGCAGGCGTACAAGGTCTTTAAGGAGGAGAAGTACTT GAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGCAGCGAGGTTTGCTGCGGAAGGGCTACGGGATATGCCATGGGACTGCTGGCAACGG CTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGGATAAGAAGTACCTCTACCGAGCTTGCAAGTTTGCAGAGTGGTGTCTAGATTACGG AGCACACGGGTGCCGCATTCCTGACAGACCCTATTCGCTCTTTGAAGGCATGGCTGGCGCTATTCACTTTCTCTCTGATGTCCTGGGACC AGAGACATCACGGTTTCCAGCATTTGAACTTGACTCTTCGAAGAGGGATTAAAAGGTGCAAAAAGACAACTAAAATACCCATTTGGACCA AAAGCCACCAGATTGCTTAGTGCCTGACACAGAAACAACTGGGAATCCTGAAAGAGAAGCAGACACCGTCACAGGCCCCTCTGGTTAGAC TAGCATGAGTGACCGAAGCCATCCATCAACATTTTCTAACAGCACCCTCATCAATATAAAATATGACTTCTTCACATACAGATTCTCTGT AGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCAGGTGTAAGCTGTTTTAAATGGAAGGCCCTTCTATTCCTGAGGGCTCAGAGCTGAC CATGCATGAATGTATGGCAGTGTCCACTTTTCTGTATAAAATGTATAAAGTGGGGTTTCTTCCATATTGACAAATGAGGGAACAGGTGGT GTCTATCTTGTATATCAGAAAGATTATCTAGGGTCTATCCTAGTGATAATACATTGTCAGCCTTTTCTGTGGCACCTTCCAGATGAGAAT GAGGGAGCGACCACTCCAAGGACGGACAGGACCAGCAGTTCTGCAGGGGCGTGCTGGGGTGGTTTGGGAGTGCACAGCTGAACGCTTCCC GTTTGGATTTTACACTCACCTTCGTGTTTTAAAGAAGCCTCAGAGTGCATTGCAGCTCTGTCAGGGCCCCATTCCCAGCAGAGGCTTCAG GTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTTGTTGGGGAGACTTCTGGACCCAAAGGGAGCTTTCCCAAGAAGCCTTTGATGGCCA CACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTCCAGAACATTTACCCAGGTATATGTTACTAAAACAGGCTCCACCTCAGTTTATCAA CATTATAAGTTACTGTTCTAAGAAAAGTAAATACAGTTCCAGATGGGTTATTGCAGATTAACAGAAAGACACTCAACTGGACTCATGTCC CTGCAATTAAACTTACTTCAACCTTTTGGAAAGTTATCAAAATCTAAATTTGGAATGAATGCATTTCCTATTTTTTGTCTACTTTTGGGT GATAAAAAGTACTAGCCCTTATTTATAGATATGAGAAACATAATGTTCTAACCAACAACATTATGGTATTTGTGTGACTTTTATTTGAAA AAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCATTAATTCTATCACATAGATTTCAGTTTTTAGAAGGGTTTCTGTCATCATGGAAGA GGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAGCTAAGGCTTGTGTCATGAAAGACAAGAGGCCTCTCTTAACAGCCCAGTCCTTGTC TGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGTGTCCACACCTCTCAGAAAAGAGAAAAAAGAATGTCAGTTTAGGAGAAAAGCTTCC TTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACCCGAAATGTGTGACATTCAGCTTCTAAACGATGCCTGGAGAGTCTGTTTGCTGCAG ACACCCTTGCTCCTGAGTCATTATTTTCTTTCATGTTAGATTGATGACTTCTGTGAATAGAAATCATCCTGATCCTATTTTACCTGGCCT CCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAGCAGCCCACACCTGCAGGCAGGATGCTGTCGTCAATGAGCTGAGGGTAGCTGCTTT GCTGAAGACCTCACACGATGTCCAATCTCATCCAAATAACATTGTTCCCATCCTCCCCACCCACCACATCAAAACATAACACATCACAGC ACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGGGAAGCCAGTAGGCAACACAGCCAGCACGGTGCTCTCCAGGGCAGCCCCTCTCAGA CGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGAGCAGCCACAAAGGTGGCCTAGGATGCGGGTGTCTCCCCAGGTGAGTCCATCCACA CACGTTTGAAAAACACTATTAGTCTTTCTAACACACTGAGGGAAAGATTAAAATCTGTGGAATAAAGGAGGAGATTTTATTTACAGATTT TTTTAAAAGCCACCTGGGTTGACACCTTCCTACTTATCCACTAGATGTCATCAGAGGTGCTGTTCCGTGGTTCTGCATTAACCCCTGCCT CATGTCTGTAACATGTGACAGTAATTCCAGCTCGGTCCCTCCAGGCAAAGGAGAAACGGGACTTACTTCACAGGACAGAGGATTGACAGA AGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCAGTACATCTCATTCATTTCTTAGATTTGTATTCACAATTGTGTTCTCTAAAATGTG TCTAAATTTTAAAAATATGTACATGCATAATGTCATTTTAAAATCTGAAGGAAAGAATTTGAAGTCCACAAAAAGTGTTTGAGGTTCTTT >30541_30541_1_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000242209_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=800AA_BP=457 MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQL ITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDG TLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPEN CERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIH VIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHL GYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQES DLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKV DQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGT -------------------------------------------------------------- >30541_30541_2_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000490776_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=4207nt_BP=754nt AAAGGCCAGTGGAAGGAGCTCAGGCTTGGCGGCATCTGGTTTGCTTGTCTGGGCCTACTCCTTTGCATGATATAACAAATGGCAGGGAAA GACATTCCCGGTCAGGCATCTCTGGTGTTTGATGTTGCATTATTGGACCTCCATAACCCCAAGGACAGCATTTCCATTGAGAACAAGGTA GTACCTGAAAACTGTGAGCGGATAAGTCAAAGTGGGGACTTTCTCAGGTATCATTACAATGGCACGCTTCTGGATGGCACCCTCTTTGAT TCCAGCTACTCTCGGAACCGCACGTTTGACACGTACATTGGGCAGGGCTACGTGATTCCTGGGATGGATGAAGGTCTACTTGGTGTTTGC ATTGGAGAAAAGCGAAGGATTGTGGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAAGAGGGAATATCCCCGGCTCGGCTGTGCTGGTG TTTGACATCCATGTGATCGACTTCCACAACCCTTCGGACTCCATCAGCATCACCTCCCACTACAAACCCCCTGACTGCTCAGTGCTGAGT AAGAAGGGAGATTACCTCAAATATCACTACAATGCCTCACTTCTGGATGGGACCCTGCTGGACTCCACGTGGAATTTAGGCAAAACTTAC AATATTGTTCTGGGATCTGGGCAAGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGATGTGCGTTGGCGAGAAACGGACAGTGATCATT CCGCCTCACCTGGGCTATGGGGAAGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGTTGTACCGGGTCACATGTGACCAAACCTACCTG CTCCGATCCCTGGATTACGTAAAAAGAACACTTCGGAATCTGAATGGCCGCAGGGTCACCTTCCTCTGTGGGGATGCTGGCCCCCTGGCT GTTGGAGCTGTGATTTATCACAAACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCACAAAACTTTTGCAGCTCCAGAGATCGGTTGTC TGCCAAGAATCAGACCTTCCTGATGAGCTGCTTTATGGACGGGCAGGTTATCTGTATGCCTTACTGTACCTGAACACAGAGATAGGTCCA GGCACCGTGTGTGAGTCAGCTATTAAAGAGGTAGTCAATGCTATTATTGAATCGGGTAAGACTTTGTCAAGGGAAGAAAGAAAAACGGAG CGCTGCCCGCTGTTGTACCAGTGGCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCATGGCTGGAATTTACTATATGTTAATGCAGCCG GCAGCAAAAGTGGACCAAGAAACCTTGACAGAAATGGTGAAACCCAGTATTGATTATGTGCGCCACAAAAAATTCCGATCTGGGAATTAC CCATCATCATTAAGCAATGAAACAGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGGGGGTCATCCACATGCTCATGCAGGCGTACAAG GTCTTTAAGGAGGAGAAGTACTTGAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGCAGCGAGGTTTGCTGCGGAAGGGCTACGGGATA TGCCATGGGACTGCTGGCAACGGCTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGGATAAGAAGTACCTCTACCGAGCTTGCAAGTTT GCAGAGTGGTGTCTAGATTACGGAGCACACGGGTGCCGCATTCCTGACAGACCCTATTCGCTCTTTGAAGGCATGGCTGGCGCTATTCAC TTTCTCTCTGATGTCCTGGGACCAGAGACATCACGGTTTCCAGCATTTGAACTTGACTCTTCGAAGAGGGATTAAAAGGTGCAAAAAGAC AACTAAAATACCCATTTGGACCAAAAGCCACCAGATTGCTTAGTGCCTGACACAGAAACAACTGGGAATCCTGAAAGAGAAGCAGACACC GTCACAGGCCCCTCTGGTTAGACTAGCATGAGTGACCGAAGCCATCCATCAACATTTTCTAACAGCACCCTCATCAATATAAAATATGAC TTCTTCACATACAGATTCTCTGTAGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCAGGTGTAAGCTGTTTTAAATGGAAGGCCCTTCT ATTCCTGAGGGCTCAGAGCTGACCATGCATGAATGTATGGCAGTGTCCACTTTTCTGTATAAAATGTATAAAGTGGGGTTTCTTCCATAT TGACAAATGAGGGAACAGGTGGTGTCTATCTTGTATATCAGAAAGATTATCTAGGGTCTATCCTAGTGATAATACATTGTCAGCCTTTTC TGTGGCACCTTCCAGATGAGAATGAGGGAGCGACCACTCCAAGGACGGACAGGACCAGCAGTTCTGCAGGGGCGTGCTGGGGTGGTTTGG GAGTGCACAGCTGAACGCTTCCCGTTTGGATTTTACACTCACCTTCGTGTTTTAAAGAAGCCTCAGAGTGCATTGCAGCTCTGTCAGGGC CCCATTCCCAGCAGAGGCTTCAGGTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTTGTTGGGGAGACTTCTGGACCCAAAGGGAGCTT TCCCAAGAAGCCTTTGATGGCCACACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTCCAGAACATTTACCCAGGTATATGTTACTAAAA CAGGCTCCACCTCAGTTTATCAACATTATAAGTTACTGTTCTAAGAAAAGTAAATACAGTTCCAGATGGGTTATTGCAGATTAACAGAAA GACACTCAACTGGACTCATGTCCCTGCAATTAAACTTACTTCAACCTTTTGGAAAGTTATCAAAATCTAAATTTGGAATGAATGCATTTC CTATTTTTTGTCTACTTTTGGGTGATAAAAAGTACTAGCCCTTATTTATAGATATGAGAAACATAATGTTCTAACCAACAACATTATGGT ATTTGTGTGACTTTTATTTGAAAAAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCATTAATTCTATCACATAGATTTCAGTTTTTAGA AGGGTTTCTGTCATCATGGAAGAGGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAGCTAAGGCTTGTGTCATGAAAGACAAGAGGCCT CTCTTAACAGCCCAGTCCTTGTCTGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGTGTCCACACCTCTCAGAAAAGAGAAAAAAGAAT GTCAGTTTAGGAGAAAAGCTTCCTTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACCCGAAATGTGTGACATTCAGCTTCTAAACGATG CCTGGAGAGTCTGTTTGCTGCAGACACCCTTGCTCCTGAGTCATTATTTTCTTTCATGTTAGATTGATGACTTCTGTGAATAGAAATCAT CCTGATCCTATTTTACCTGGCCTCCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAGCAGCCCACACCTGCAGGCAGGATGCTGTCGTC AATGAGCTGAGGGTAGCTGCTTTGCTGAAGACCTCACACGATGTCCAATCTCATCCAAATAACATTGTTCCCATCCTCCCCACCCACCAC ATCAAAACATAACACATCACAGCACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGGGAAGCCAGTAGGCAACACAGCCAGCACGGTGC TCTCCAGGGCAGCCCCTCTCAGACGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGAGCAGCCACAAAGGTGGCCTAGGATGCGGGTGT CTCCCCAGGTGAGTCCATCCACACACGTTTGAAAAACACTATTAGTCTTTCTAACACACTGAGGGAAAGATTAAAATCTGTGGAATAAAG GAGGAGATTTTATTTACAGATTTTTTTAAAAGCCACCTGGGTTGACACCTTCCTACTTATCCACTAGATGTCATCAGAGGTGCTGTTCCG TGGTTCTGCATTAACCCCTGCCTCATGTCTGTAACATGTGACAGTAATTCCAGCTCGGTCCCTCCAGGCAAAGGAGAAACGGGACTTACT TCACAGGACAGAGGATTGACAGAAGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCAGTACATCTCATTCATTTCTTAGATTTGTATTC ACAATTGTGTTCTCTAAAATGTGTCTAAATTTTAAAAATATGTACATGCATAATGTCATTTTAAAATCTGAAGGAAAGAATTTGAAGTCC >30541_30541_2_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000490776_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=568AA_BP=225 MAGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGL LGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNL GKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDA GPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREE RKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGVIHMLM QAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEGMA -------------------------------------------------------------- >30541_30541_3_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538336_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=5117nt_BP=1664nt AGACGGGGTGGCGGCTGCAGCCCGGGTAGGGCCAGGAGACCCGGTCCACGTTTGCAAACGCAGCCGAACGCCCAGGCCGACCCGTGCCGC CCGAGCGCCGCGCTGCGTCCGCGCCACTCTTCTCGCCGCCCCGATGGCGTTCCGGGGCTGGAGGCCCCCGCCGCCACCGCTGCTCCTGCT GCTGCTCTGGGTGACCGGGCAGGCAGCGCCCGTGGCGGGCCTGGGCTCCGACGCGGAGCTGCAGATCGAGCGGCGCTTCGTGCCCGACGA GTGCCCGCGCACCGTGCGCAGCGGCGACTTCGTGCGCTACCACTACGTGGGGACGTTCCCCGACGGCCAGAAGTTCGACTCCAGGTACTG GGATACAGCGGAGGATAAAGCTGACAAAAGTCCCTGCCCTCAAGTCAGGGTTGGGGTGAACACAAGCCCGTCCTGCAGACTTAAGCAGAA AGGAGTGGGAATTTATTGGAAGGATCTCCAATTCCTTGTGAGGGTCCAGAATCATGGACTGAGCTATGACAGAGACTCCACTTTCAATGT GTTTGTGGGAAAAGGACAGCTGATCACAGGGATGGACCAGGCTCTTGTTGGGATGTGCGTAAACGAGAGACGTTTCGTGAAGATTCCCCC AAAGCTTGCCTACGGAAATGAAGGAGTTTCTGGTGTGATCCCCCCCAATTCAGTGCTTCATTTTGATGTACTTCTGATGGATATTTGGAA TTCTGAAGACCAGGTTCAGATTCACACCTATTTCAAGCCCCCGAGTTGCCCTCGGACCATCCAGGTGTCTGATTTTGTGAGGTACCACTA CAACGGGACGTTCCTGGACGGAACTCTGTTTGATTCGAGTCACAATCGCATGAAAACATATGACACGTATGTGGGAATTGGCTGGCTGAT TCCTGGAATGGATAAAGGGCTGCTGGGGATGTGTGTGGGTGAGAAGCGCATCATCACCATTCCTCCTTTTCTGGCCTATGGAGAGGATGG AGATGGGAAAGACATTCCCGGTCAGGCATCTCTGGTGTTTGATGTTGCATTATTGGACCTCCATAACCCCAAGGACAGCATTTCCATTGA GAACAAGGTAGTACCTGAAAACTGTGAGCGGATAAGTCAAAGTGGGGACTTTCTCAGGTATCATTACAATGGCACGCTTCTGGATGGCAC CCTCTTTGATTCCAGCTACTCTCGGAACCGCACGTTTGACACGTACATTGGGCAGGGCTACGTGATTCCTGGGATGGATGAAGGTCTACT TGGTGTTTGCATTGGAGAAAAGCGAAGGATTGTGGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAAGAGGGAATATCCCCGGCTCGGC TGTGCTGGTGTTTGACATCCATGTGATCGACTTCCACAACCCTTCGGACTCCATCAGCATCACCTCCCACTACAAACCCCCTGACTGCTC AGTGCTGAGTAAGAAGGGAGATTACCTCAAATATCACTACAATGCCTCACTTCTGGATGGGACCCTGCTGGACTCCACGTGGAATTTAGG CAAAACTTACAATATTGTTCTGGGATCTGGGCAAGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGATGTGCGTTGGCGAGAAACGGAC AGTGATCATTCCGCCTCACCTGGGCTATGGGGAAGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGTTGTACCGGGTCACATGTGACCA AACCTACCTGCTCCGATCCCTGGATTACGTAAAAAGAACACTTCGGAATCTGAATGGCCGCAGGGTCACCTTCCTCTGTGGGGATGCTGG CCCCCTGGCTGTTGGAGCTGTGATTTATCACAAACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCACAAAACTTTTGCAGCTCCAGAG ATCGGTTGTCTGCCAAGAATCAGACCTTCCTGATGAGCTGCTTTATGGACGGGCAGGTTATCTGTATGCCTTACTGTACCTGAACACAGA GATAGGTCCAGGCACCGTGTGTGAGTCAGCTATTAAAGAGGTAGTCAATGCTATTATTGAATCGGGTAAGACTTTGTCAAGGGAAGAAAG AAAAACGGAGCGCTGCCCGCTGTTGTACCAGTGGCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCATGGCTGGAATTTACTATATGTT AATGCAGCCGGCAGCAAAAGTGGACCAAGAAACCTTGACAGAAATGGTGAAACCCAGTATTGATTATGTGCGCCACAAAAAATTCCGATC TGGGAATTACCCATCATCATTAAGCAATGAAACAGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGGGGGTCATCCACATGCTCATGCA GGCGTACAAGGTCTTTAAGGAGGAGAAGTACTTGAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGCAGCGAGGTTTGCTGCGGAAGGG CTACGGGATATGCCATGGGACTGCTGGCAACGGCTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGGATAAGAAGTACCTCTACCGAGC TTGCAAGTTTGCAGAGTGGTGTCTAGATTACGGAGCACACGGGTGCCGCATTCCTGACAGACCCTATTCGCTCTTTGAAGGCATGGCTGG CGCTATTCACTTTCTCTCTGATGTCCTGGGACCAGAGACATCACGGTTTCCAGCATTTGAACTTGACTCTTCGAAGAGGGATTAAAAGGT GCAAAAAGACAACTAAAATACCCATTTGGACCAAAAGCCACCAGATTGCTTAGTGCCTGACACAGAAACAACTGGGAATCCTGAAAGAGA AGCAGACACCGTCACAGGCCCCTCTGGTTAGACTAGCATGAGTGACCGAAGCCATCCATCAACATTTTCTAACAGCACCCTCATCAATAT AAAATATGACTTCTTCACATACAGATTCTCTGTAGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCAGGTGTAAGCTGTTTTAAATGGA AGGCCCTTCTATTCCTGAGGGCTCAGAGCTGACCATGCATGAATGTATGGCAGTGTCCACTTTTCTGTATAAAATGTATAAAGTGGGGTT TCTTCCATATTGACAAATGAGGGAACAGGTGGTGTCTATCTTGTATATCAGAAAGATTATCTAGGGTCTATCCTAGTGATAATACATTGT CAGCCTTTTCTGTGGCACCTTCCAGATGAGAATGAGGGAGCGACCACTCCAAGGACGGACAGGACCAGCAGTTCTGCAGGGGCGTGCTGG GGTGGTTTGGGAGTGCACAGCTGAACGCTTCCCGTTTGGATTTTACACTCACCTTCGTGTTTTAAAGAAGCCTCAGAGTGCATTGCAGCT CTGTCAGGGCCCCATTCCCAGCAGAGGCTTCAGGTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTTGTTGGGGAGACTTCTGGACCCA AAGGGAGCTTTCCCAAGAAGCCTTTGATGGCCACACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTCCAGAACATTTACCCAGGTATAT GTTACTAAAACAGGCTCCACCTCAGTTTATCAACATTATAAGTTACTGTTCTAAGAAAAGTAAATACAGTTCCAGATGGGTTATTGCAGA TTAACAGAAAGACACTCAACTGGACTCATGTCCCTGCAATTAAACTTACTTCAACCTTTTGGAAAGTTATCAAAATCTAAATTTGGAATG AATGCATTTCCTATTTTTTGTCTACTTTTGGGTGATAAAAAGTACTAGCCCTTATTTATAGATATGAGAAACATAATGTTCTAACCAACA ACATTATGGTATTTGTGTGACTTTTATTTGAAAAAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCATTAATTCTATCACATAGATTTC AGTTTTTAGAAGGGTTTCTGTCATCATGGAAGAGGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAGCTAAGGCTTGTGTCATGAAAGA CAAGAGGCCTCTCTTAACAGCCCAGTCCTTGTCTGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGTGTCCACACCTCTCAGAAAAGAG AAAAAAGAATGTCAGTTTAGGAGAAAAGCTTCCTTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACCCGAAATGTGTGACATTCAGCTT CTAAACGATGCCTGGAGAGTCTGTTTGCTGCAGACACCCTTGCTCCTGAGTCATTATTTTCTTTCATGTTAGATTGATGACTTCTGTGAA TAGAAATCATCCTGATCCTATTTTACCTGGCCTCCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAGCAGCCCACACCTGCAGGCAGGA TGCTGTCGTCAATGAGCTGAGGGTAGCTGCTTTGCTGAAGACCTCACACGATGTCCAATCTCATCCAAATAACATTGTTCCCATCCTCCC CACCCACCACATCAAAACATAACACATCACAGCACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGGGAAGCCAGTAGGCAACACAGCC AGCACGGTGCTCTCCAGGGCAGCCCCTCTCAGACGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGAGCAGCCACAAAGGTGGCCTAGG ATGCGGGTGTCTCCCCAGGTGAGTCCATCCACACACGTTTGAAAAACACTATTAGTCTTTCTAACACACTGAGGGAAAGATTAAAATCTG TGGAATAAAGGAGGAGATTTTATTTACAGATTTTTTTAAAAGCCACCTGGGTTGACACCTTCCTACTTATCCACTAGATGTCATCAGAGG TGCTGTTCCGTGGTTCTGCATTAACCCCTGCCTCATGTCTGTAACATGTGACAGTAATTCCAGCTCGGTCCCTCCAGGCAAAGGAGAAAC GGGACTTACTTCACAGGACAGAGGATTGACAGAAGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCAGTACATCTCATTCATTTCTTAG ATTTGTATTCACAATTGTGTTCTCTAAAATGTGTCTAAATTTTAAAAATATGTACATGCATAATGTCATTTTAAAATCTGAAGGAAAGAA >30541_30541_3_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538336_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=853AA_BP=510 MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSRYWDTAEDKADKSPCPQ VRVGVNTSPSCRLKQKGVGIYWKDLQFLVRVQNHGLSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIP PNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGE KRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDT YIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYN ASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTL RNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEV VNAIIESGKTLSREERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRL VHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHG -------------------------------------------------------------- >30541_30541_4_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538443_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=4779nt_BP=1326nt AGGAGACCCGGTCCACGTTTGCAAACGCAGCCGAACGCCCAGGCCGACCCGTGCCGCCCGAGCGCCGCGCTGCGTCCGCGCCACTCTTCT CGCCGCCCCGATGGCGTTCCGGGGCTGGAGGCCCCCGCCGCCACCGCTGCTCCTGCTGCTGCTCTGGGTGACCGGGCAGGCAGCGCCCGT GGCGGGCCTGGGCTCCGACGCGGAGCTGCAGATCGAGCGGCGCTTCGTGCCCGACGAGTGCCCGCGCACCGTGCGCAGCGGCGACTTCGT GCGCTACCACTACGTGGGGACGTTCCCCGACGGCCAGAAGTTCGACTCCAGCTGGTGTGATCCCCCCCAATTCAGTGCTTCATTTTGATG TACTTCTGATGGATATTTGGAATTCTGAAGACCAGGTTCAGATTCACACCTATTTCAAGCCCCCGAGTTGCCCTCGGACCATCCAGGTGT CTGATTTTGTGAGGTACCACTACAACGGGACGTTCCTGGACGGAACTCTGTTTGATTCGAGTCACAATCGCATGAAAACATATGACACGT ATGTGGGAATTGGCTGGCTGATTCCTGGAATGGATAAAGGGCTGCTGGGGATGTGTGTGGGTGAGAAGCGCATCATCACCATTCCTCCTT TTCTGGCCTATGGAGAGGATGGAGATGGGAAAGACATTCCCGGTCAGGCATCTCTGGTGTTTGATGTTGCATTATTGGACCTCCATAACC CCAAGGACAGCATTTCCATTGAGAACAAGGTAGTACCTGAAAACTGTGAGCGGATAAGTCAAAGTGGGGACTTTCTCAGGTATCATTACA ATGGCACGCTTCTGGATGGCACCCTCTTTGATTCCAGCTACTCTCGGAACCGCACGTTTGACACGTACATTGGGCAGGGCTACGTGATTC CTGGGATGGATGAAGGTCTACTTGGTGTTTGCATTGGAGAAAAGCGAAGGATTGTGGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAA GAGGGAATATCCCCGGCTCGGCTGTGCTGGTGTTTGACATCCATGTGATCGACTTCCACAACCCTTCGGACTCCATCAGCATCACCTCCC ACTACAAACCCCCTGACTGCTCAGTGCTGAGTAAGAAGGGAGATTACCTCAAATATCACTACAATGCCTCACTTCTGGATGGGACCCTGC TGGACTCCACGTGGAATTTAGGCAAAACTTACAATATTGTTCTGGGATCTGGGCAAGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGA TGTGCGTTGGCGAGAAACGGACAGTGATCATTCCGCCTCACCTGGGCTATGGGGAAGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGT TGTACCGGGTCACATGTGACCAAACCTACCTGCTCCGATCCCTGGATTACGTAAAAAGAACACTTCGGAATCTGAATGGCCGCAGGGTCA CCTTCCTCTGTGGGGATGCTGGCCCCCTGGCTGTTGGAGCTGTGATTTATCACAAACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCA CAAAACTTTTGCAGCTCCAGAGATCGGTTGTCTGCCAAGAATCAGACCTTCCTGATGAGCTGCTTTATGGACGGGCAGGTTATCTGTATG CCTTACTGTACCTGAACACAGAGATAGGTCCAGGCACCGTGTGTGAGTCAGCTATTAAAGAGGTAGTCAATGCTATTATTGAATCGGGTA AGACTTTGTCAAGGGAAGAAAGAAAAACGGAGCGCTGCCCGCTGTTGTACCAGTGGCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCA TGGCTGGAATTTACTATATGTTAATGCAGCCGGCAGCAAAAGTGGACCAAGAAACCTTGACAGAAATGGTGAAACCCAGTATTGATTATG TGCGCCACAAAAAATTCCGATCTGGGAATTACCCATCATCATTAAGCAATGAAACAGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGG GGGTCATCCACATGCTCATGCAGGCGTACAAGGTCTTTAAGGAGGAGAAGTACTTGAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGC AGCGAGGTTTGCTGCGGAAGGGCTACGGGATATGCCATGGGACTGCTGGCAACGGCTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGG ATAAGAAGTACCTCTACCGAGCTTGCAAGTTTGCAGAGTGGTGTCTAGATTACGGAGCACACGGGTGCCGCATTCCTGACAGACCCTATT CGCTCTTTGAAGGCATGGCTGGCGCTATTCACTTTCTCTCTGATGTCCTGGGACCAGAGACATCACGGTTTCCAGCATTTGAACTTGACT CTTCGAAGAGGGATTAAAAGGTGCAAAAAGACAACTAAAATACCCATTTGGACCAAAAGCCACCAGATTGCTTAGTGCCTGACACAGAAA CAACTGGGAATCCTGAAAGAGAAGCAGACACCGTCACAGGCCCCTCTGGTTAGACTAGCATGAGTGACCGAAGCCATCCATCAACATTTT CTAACAGCACCCTCATCAATATAAAATATGACTTCTTCACATACAGATTCTCTGTAGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCA GGTGTAAGCTGTTTTAAATGGAAGGCCCTTCTATTCCTGAGGGCTCAGAGCTGACCATGCATGAATGTATGGCAGTGTCCACTTTTCTGT ATAAAATGTATAAAGTGGGGTTTCTTCCATATTGACAAATGAGGGAACAGGTGGTGTCTATCTTGTATATCAGAAAGATTATCTAGGGTC TATCCTAGTGATAATACATTGTCAGCCTTTTCTGTGGCACCTTCCAGATGAGAATGAGGGAGCGACCACTCCAAGGACGGACAGGACCAG CAGTTCTGCAGGGGCGTGCTGGGGTGGTTTGGGAGTGCACAGCTGAACGCTTCCCGTTTGGATTTTACACTCACCTTCGTGTTTTAAAGA AGCCTCAGAGTGCATTGCAGCTCTGTCAGGGCCCCATTCCCAGCAGAGGCTTCAGGTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTT GTTGGGGAGACTTCTGGACCCAAAGGGAGCTTTCCCAAGAAGCCTTTGATGGCCACACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTC CAGAACATTTACCCAGGTATATGTTACTAAAACAGGCTCCACCTCAGTTTATCAACATTATAAGTTACTGTTCTAAGAAAAGTAAATACA GTTCCAGATGGGTTATTGCAGATTAACAGAAAGACACTCAACTGGACTCATGTCCCTGCAATTAAACTTACTTCAACCTTTTGGAAAGTT ATCAAAATCTAAATTTGGAATGAATGCATTTCCTATTTTTTGTCTACTTTTGGGTGATAAAAAGTACTAGCCCTTATTTATAGATATGAG AAACATAATGTTCTAACCAACAACATTATGGTATTTGTGTGACTTTTATTTGAAAAAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCA TTAATTCTATCACATAGATTTCAGTTTTTAGAAGGGTTTCTGTCATCATGGAAGAGGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAG CTAAGGCTTGTGTCATGAAAGACAAGAGGCCTCTCTTAACAGCCCAGTCCTTGTCTGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGT GTCCACACCTCTCAGAAAAGAGAAAAAAGAATGTCAGTTTAGGAGAAAAGCTTCCTTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACC CGAAATGTGTGACATTCAGCTTCTAAACGATGCCTGGAGAGTCTGTTTGCTGCAGACACCCTTGCTCCTGAGTCATTATTTTCTTTCATG TTAGATTGATGACTTCTGTGAATAGAAATCATCCTGATCCTATTTTACCTGGCCTCCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAG CAGCCCACACCTGCAGGCAGGATGCTGTCGTCAATGAGCTGAGGGTAGCTGCTTTGCTGAAGACCTCACACGATGTCCAATCTCATCCAA ATAACATTGTTCCCATCCTCCCCACCCACCACATCAAAACATAACACATCACAGCACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGG GAAGCCAGTAGGCAACACAGCCAGCACGGTGCTCTCCAGGGCAGCCCCTCTCAGACGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGA GCAGCCACAAAGGTGGCCTAGGATGCGGGTGTCTCCCCAGGTGAGTCCATCCACACACGTTTGAAAAACACTATTAGTCTTTCTAACACA CTGAGGGAAAGATTAAAATCTGTGGAATAAAGGAGGAGATTTTATTTACAGATTTTTTTAAAAGCCACCTGGGTTGACACCTTCCTACTT ATCCACTAGATGTCATCAGAGGTGCTGTTCCGTGGTTCTGCATTAACCCCTGCCTCATGTCTGTAACATGTGACAGTAATTCCAGCTCGG TCCCTCCAGGCAAAGGAGAAACGGGACTTACTTCACAGGACAGAGGATTGACAGAAGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCA GTACATCTCATTCATTTCTTAGATTTGTATTCACAATTGTGTTCTCTAAAATGTGTCTAAATTTTAAAAATATGTACATGCATAATGTCA TTTTAAAATCTGAAGGAAAGAATTTGAAGTCCACAAAAAGTGTTTGAGGTTCTTTGGTTTTGTTAGTAAAAGCCAGTTCTGTGGTGATGA >30541_30541_4_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538443_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=663AA_BP=320 MMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFL AYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPG MDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLD STWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTLRNLNGRRVTF LCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKT LSREERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGV IHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for FKBP9-LANCL2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | LANCL2 | chr7:33039872 | chr7:55466116 | ENST00000254770 | 1 | 9 | 2_15 | 107.33333333333333 | 451.0 | inositol phospholipids |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for FKBP9-LANCL2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for FKBP9-LANCL2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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