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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:FKTN-ULK4 (FusionGDB2 ID:30551)

Fusion Gene Summary for FKTN-ULK4

Fusion gene summary

Fusion gene information	Fusion gene name: FKTN-ULK4
	Fusion gene ID: 30551
		Hgene	Tgene
	Gene symbol	FKTN	ULK4
	Gene ID	2218	54986
	Gene name	fukutin	unc-51 like kinase 4
	Synonyms	CMD1X\|FCMD\|LGMD2M\|LGMDR13\|MDDGA4\|MDDGB4\|MDDGC4	FAM7C1\|REC01035
	Cytomap	9q31.2	3p22.1
	Type of gene	protein-coding	protein-coding
	Description	fukutinFukuyama type congenital muscular dystrophy proteinpatient fukutinribitol-5-phosphate transferase	serine/threonine-protein kinase ULK4
	Modification date	20200328	20200313
	UniProtAcc	O75072	.
	Ensembl transtripts involved in fusion gene	ENST00000490134, ENST00000223528, ENST00000357998, ENST00000448551, ENST00000540160, ENST00000602661,	ENST00000301831, ENST00000414606, ENST00000420927, ENST00000489118,
Fusion gene scores	* DoF score	3 X 3 X 3=27	14 X 21 X 5=1470
	# samples	3	18
	** MAII score	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(18/1470*10)=-3.02974734339405 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: FKTN [Title/Abstract] AND ULK4 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	FKTN(108358938)-ULK4(41795980), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across FKTN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ULK4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-FP-A8CX-01A	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-

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Fusion Gene ORF analysis for FKTN-ULK4

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000490134	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
3UTR-intron	ENST00000490134	ENST00000414606	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
3UTR-intron	ENST00000490134	ENST00000420927	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
3UTR-intron	ENST00000490134	ENST00000489118	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000223528	ENST00000414606	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000223528	ENST00000420927	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000223528	ENST00000489118	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000357998	ENST00000414606	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000357998	ENST00000420927	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000357998	ENST00000489118	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000448551	ENST00000414606	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000448551	ENST00000420927	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000448551	ENST00000489118	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000540160	ENST00000414606	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000540160	ENST00000420927	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000540160	ENST00000489118	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000602661	ENST00000414606	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000602661	ENST00000420927	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
5CDS-intron	ENST00000602661	ENST00000489118	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
In-frame	ENST00000223528	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
In-frame	ENST00000357998	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
In-frame	ENST00000448551	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
In-frame	ENST00000540160	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-
In-frame	ENST00000602661	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000602661	FKTN	chr9	108358938	-	ENST00000301831	ULK4	chr3	41795980	-	2338	381	216	2015	599
ENST00000223528	FKTN	chr9	108358938	-	ENST00000301831	ULK4	chr3	41795980	-	2246	289	124	1923	599
ENST00000540160	FKTN	chr9	108358938	-	ENST00000301831	ULK4	chr3	41795980	-	2244	287	122	1921	599
ENST00000448551	FKTN	chr9	108358938	-	ENST00000301831	ULK4	chr3	41795980	-	2336	379	214	2013	599
ENST00000357998	FKTN	chr9	108358938	-	ENST00000301831	ULK4	chr3	41795980	-	2238	281	116	1915	599

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000602661	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-	0.003905812	0.99609417
ENST00000223528	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-	0.005059442	0.99494064
ENST00000540160	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-	0.005196078	0.99480385
ENST00000448551	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-	0.004016915	0.9959831
ENST00000357998	ENST00000301831	FKTN	chr9	108358938	-	ULK4	chr3	41795980	-	0.004223797	0.99577624

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Fusion Genomic Features for FKTN-ULK4

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FKTN-ULK4

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:108358938/chr3:41795980)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
FKTN O75072	.
FUNCTION: Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:17034757, PubMed:25279699, PubMed:26923585, PubMed:29477842). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1 (PubMed:17034757, PubMed:25279699, PubMed:26923585, PubMed:29477842). Required for normal location of POMGNT1 in Golgi membranes, and for normal POMGNT1 activity (PubMed:17034757). May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes (PubMed:25279699). Could be involved in brain development (Probable). {ECO:0000269\|PubMed:17034757, ECO:0000269\|PubMed:25279699, ECO:0000269\|PubMed:26923585, ECO:0000269\|PubMed:29477842, ECO:0000305\|PubMed:11115853}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000223528

1_7

462.0

Topological domain

Cytoplasmic

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000357998

1_7

431.0

Topological domain

Cytoplasmic

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000448551

1_7

431.0

Topological domain

Cytoplasmic

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000602661

1_7

462.0

Topological domain

Cytoplasmic

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000223528

8_28

462.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000357998

8_28

431.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000448551

8_28

431.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000602661

8_28

462.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000301831

1147_1150

731

1276.0

Compositional bias

Note=Poly-Leu

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000420927

1147_1150

581.0

Compositional bias

Note=Poly-Leu

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000420927

4_280

581.0

Domain

Protein kinase

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000301831

1025_1063

731

1276.0

Repeat

Note=HEAT 3

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000301831

1151_1189

731

1276.0

Repeat

Note=HEAT 4

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000301831

1213_1253

731

1276.0

Repeat

Note=HEAT 5

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000301831

842_880

731

1276.0

Repeat

Note=HEAT 1

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000301831

926_964

731

1276.0

Repeat

Note=HEAT 2

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000420927

1025_1063

581.0

Repeat

Note=HEAT 3

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000420927

1151_1189

581.0

Repeat

Note=HEAT 4

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000420927

1213_1253

581.0

Repeat

Note=HEAT 5

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000420927

842_880

581.0

Repeat

Note=HEAT 1

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000420927

926_964

581.0

Repeat

Note=HEAT 2

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000223528

29_461

462.0

Topological domain

Lumenal

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000357998

29_461

431.0

Topological domain

Lumenal

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000448551

29_461

431.0

Topological domain

Lumenal

Hgene

FKTN

chr9:108358938

chr3:41795980

ENST00000602661

29_461

462.0

Topological domain

Lumenal

Tgene

ULK4

chr9:108358938

chr3:41795980

ENST00000301831

4_280

731

1276.0

Domain

Protein kinase

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Fusion Gene Sequence for FKTN-ULK4

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>30551_30551_1_FKTN-ULK4_FKTN_chr9_108358938_ENST00000223528_ULK4_chr3_41795980_ENST00000301831_length(transcript)=2246nt_BP=289nt
GTAAAGCGGAGCGGCTGCAGCCTGCTGTTGAGTGAGAAAACAAAATTATCTTCCTTTCCAAATCCAAAAAGATGAAAACGACTGAGATAC
TTTCAAAAGACAACCAAGTGAGCAGCACAGACTAATGAGTAGAATCAATAAGAACGTGGTTTTGGCCCTTTTAACGCTGACAAGTTCTGC
ATTTCTGCTGTTTCAGTTGTACTACTACAAGCACTATTTATCAACAAAGAATGGAGCTGGTTTGTCAAAATCCAAAGGAAGCCGAATTGG
ATTTGATAGCACACAGTGGGGTTTTGTCTCCACAATTATCCGTTTACTTGACAGCCCCTCAACATGCATTAGAGCAAAAGCCTTCCTGGT
TCTTCTATATATTTTGATTTATAACCGTGAGATGTTGCTGCTCAGTTGCCAAGCAAGACTGGTGATGTACATCGAGAGAGACAGCAGAAA
GACCACTCCAGGCAAGGAGCAGCAAAGTGGCAATGAATACCTGTCCAAATGCCTGGATCTTCTCATCTGTCACATTGTGCAGGAGCTGCC
ACGAATCCTGGGTGACATTCTTAACTCCTTGGCTAATGTTTCTGGACGTAAACACCCATCAACAGTTCAAGTGAAACAGCTGAAGTTGTG
TCTCCCCCTGATGCCTGTAGTGCTTCACCTCGTAACTTCACAGGTATTTCGACCTCAAGTTGTGACAGAAGAGTTTCTTTTCAGCTATGG
AACTATTCTTAGTCATATTAAATCTGTAGACTCAGGAGAAACGAACATAGATGGAGCCATAGGACTGACAGCATCAGAAGAATTTATCAA
GATCACATTGTCAGCTTTTGAAGCAATAATACAGTATCCTATTTTATTGAAAGACTATCGCTCCACGGTTGTTGACTATATACTGCCACC
CTTGGTGTCCTTGGTTCAAAGCCAAAATGTGGAGTGGAGACTCTTTAGCTTGCGGTTGCTCTCAGAAACCACATCTCTACTCGTGAACCA
GGAGTTTGGGGATGGCAAGGAGAAGGCCAGTGTTGATTCTGACAGCAATCTTCTGGCTCTCATTCGAGATGTCTTACTTCCCCAGTATGA
GCACATTCTTTTAGAACCTGACCCAGTACCAGCATATGCTCTGAAACTGCTAGTCGCGATGACTGAACACAACCCAACTTTCACAAGACT
TGTGGAAGAAAGCAAACTGATCCCACTCATTTTTGAAGTAACTCTGGAACATCAGGAGAGCATTCTGGGTAATACCATGCAAAGTGTGAT
TGCATTACTCAGCAATCTAGTTGCCTGCAAAGATTCGAATATGGAACTACTTTATGAACAAGGACTTGTCAGTCACATCTGTAACCTGCT
CACTGAAACTGCCACACTGTGCTTGGATGTGGACAATAAAAACAACAATGAGATGGCAGCTCCACTGCTCTTTTCCCTGCTTGATATTTT
GCACAGCATGCTGACCTATACCTCCGGTATTGTACGGCTGGCTTTGCAGGCCCAGAAGTCTGGCTCAGGAGAGGACCCTCAGGCTGCAGA
AGACCTGCTGCTGCTCAACAGACCTCTGACAGACCTGATTAGCCTGCTCATTCCACTGCTTCCTAATGAAGATCCTGAGATTTTTGATGT
TTCATCCAAGTGCCTGTCTATACTGGTTCAGCTGTATGGAGGGGAAAACCCGGACAGCCTCTCTCCTGAAAATGTGGAAATTTTTGCTCA
TTTACTGACATCCAAGGAGGACCCAAAGGAGCAGAAGCTTCTGTTAAGGATTCTCAGAAGAATGATCACCTCCAATGAGAAGCACTTGGA
GAGCCTCAAGAATGCAGGCAGCCTCCTGCGGGCTCTGGAGCGGCTGGCCCCTGGGAGTGGTTCATTTGCCGACAGTGCGGTGGCTCCCTT
GGCCCTGGAAATCCTCCAAGCCGTTGGGCACTAGGCAAGAAGGTGCTTAGCACAAGCCCGCCCTGTGGCCCCAGCCCTCGGATGCATAAG
CAAGGTCAGCTCCCAGACACCTTTGCCACATCCCCTCACAGCTGTCTTTGGACCTAATAAAGTCAGCTTAACCCAGAACCTGGTGGCCCA
AGTGCTCACTAACCCCAGGGCCTAGAAAACTGACTCAGAATGGACTTCCTTGGTTCCTGTGGAATGCATCTGGGAAGCCCAGGTTTGTTA

>30551_30551_1_FKTN-ULK4_FKTN_chr9_108358938_ENST00000223528_ULK4_chr3_41795980_ENST00000301831_length(amino acids)=599AA_BP=55
MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSTKNGAGLSKSKGSRIGFDSTQWGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREM
LLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLV
TSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVE
WRLFSLRLLSETTSLLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIF
EVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIV
RLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQ

--------------------------------------------------------------
>30551_30551_2_FKTN-ULK4_FKTN_chr9_108358938_ENST00000357998_ULK4_chr3_41795980_ENST00000301831_length(transcript)=2238nt_BP=281nt
TCTTTAAAAATATCTTTTTTGTTCACAGAAAACAAAATTATCTTCCTTTCCAAATCCAAAAAGATGAAAACGACTGAGATACTTTCAAAA
GACAACCAAGTGAGCAGCACAGACTAATGAGTAGAATCAATAAGAACGTGGTTTTGGCCCTTTTAACGCTGACAAGTTCTGCATTTCTGC
TGTTTCAGTTGTACTACTACAAGCACTATTTATCAACAAAGAATGGAGCTGGTTTGTCAAAATCCAAAGGAAGCCGAATTGGATTTGATA
GCACACAGTGGGGTTTTGTCTCCACAATTATCCGTTTACTTGACAGCCCCTCAACATGCATTAGAGCAAAAGCCTTCCTGGTTCTTCTAT
ATATTTTGATTTATAACCGTGAGATGTTGCTGCTCAGTTGCCAAGCAAGACTGGTGATGTACATCGAGAGAGACAGCAGAAAGACCACTC
CAGGCAAGGAGCAGCAAAGTGGCAATGAATACCTGTCCAAATGCCTGGATCTTCTCATCTGTCACATTGTGCAGGAGCTGCCACGAATCC
TGGGTGACATTCTTAACTCCTTGGCTAATGTTTCTGGACGTAAACACCCATCAACAGTTCAAGTGAAACAGCTGAAGTTGTGTCTCCCCC
TGATGCCTGTAGTGCTTCACCTCGTAACTTCACAGGTATTTCGACCTCAAGTTGTGACAGAAGAGTTTCTTTTCAGCTATGGAACTATTC
TTAGTCATATTAAATCTGTAGACTCAGGAGAAACGAACATAGATGGAGCCATAGGACTGACAGCATCAGAAGAATTTATCAAGATCACAT
TGTCAGCTTTTGAAGCAATAATACAGTATCCTATTTTATTGAAAGACTATCGCTCCACGGTTGTTGACTATATACTGCCACCCTTGGTGT
CCTTGGTTCAAAGCCAAAATGTGGAGTGGAGACTCTTTAGCTTGCGGTTGCTCTCAGAAACCACATCTCTACTCGTGAACCAGGAGTTTG
GGGATGGCAAGGAGAAGGCCAGTGTTGATTCTGACAGCAATCTTCTGGCTCTCATTCGAGATGTCTTACTTCCCCAGTATGAGCACATTC
TTTTAGAACCTGACCCAGTACCAGCATATGCTCTGAAACTGCTAGTCGCGATGACTGAACACAACCCAACTTTCACAAGACTTGTGGAAG
AAAGCAAACTGATCCCACTCATTTTTGAAGTAACTCTGGAACATCAGGAGAGCATTCTGGGTAATACCATGCAAAGTGTGATTGCATTAC
TCAGCAATCTAGTTGCCTGCAAAGATTCGAATATGGAACTACTTTATGAACAAGGACTTGTCAGTCACATCTGTAACCTGCTCACTGAAA
CTGCCACACTGTGCTTGGATGTGGACAATAAAAACAACAATGAGATGGCAGCTCCACTGCTCTTTTCCCTGCTTGATATTTTGCACAGCA
TGCTGACCTATACCTCCGGTATTGTACGGCTGGCTTTGCAGGCCCAGAAGTCTGGCTCAGGAGAGGACCCTCAGGCTGCAGAAGACCTGC
TGCTGCTCAACAGACCTCTGACAGACCTGATTAGCCTGCTCATTCCACTGCTTCCTAATGAAGATCCTGAGATTTTTGATGTTTCATCCA
AGTGCCTGTCTATACTGGTTCAGCTGTATGGAGGGGAAAACCCGGACAGCCTCTCTCCTGAAAATGTGGAAATTTTTGCTCATTTACTGA
CATCCAAGGAGGACCCAAAGGAGCAGAAGCTTCTGTTAAGGATTCTCAGAAGAATGATCACCTCCAATGAGAAGCACTTGGAGAGCCTCA
AGAATGCAGGCAGCCTCCTGCGGGCTCTGGAGCGGCTGGCCCCTGGGAGTGGTTCATTTGCCGACAGTGCGGTGGCTCCCTTGGCCCTGG
AAATCCTCCAAGCCGTTGGGCACTAGGCAAGAAGGTGCTTAGCACAAGCCCGCCCTGTGGCCCCAGCCCTCGGATGCATAAGCAAGGTCA
GCTCCCAGACACCTTTGCCACATCCCCTCACAGCTGTCTTTGGACCTAATAAAGTCAGCTTAACCCAGAACCTGGTGGCCCAAGTGCTCA
CTAACCCCAGGGCCTAGAAAACTGACTCAGAATGGACTTCCTTGGTTCCTGTGGAATGCATCTGGGAAGCCCAGGTTTGTTAGCTGTTCT

>30551_30551_2_FKTN-ULK4_FKTN_chr9_108358938_ENST00000357998_ULK4_chr3_41795980_ENST00000301831_length(amino acids)=599AA_BP=55
MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSTKNGAGLSKSKGSRIGFDSTQWGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREM
LLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLV
TSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVE
WRLFSLRLLSETTSLLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIF
EVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIV
RLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQ

--------------------------------------------------------------
>30551_30551_3_FKTN-ULK4_FKTN_chr9_108358938_ENST00000448551_ULK4_chr3_41795980_ENST00000301831_length(transcript)=2336nt_BP=379nt
AAAGCGGAGCGGCTGCAGCCTGCTGTTGAGTGAGATTGAAAGGAAACACACTGAATGAGGAAAAACTAACATACGGTCATCAACATCCTT
GTATAACCTAGTTTTTAAAAAAATTGGATTTCAAAGAAAACAAAATTATCTTCCTTTCCAAATCCAAAAAGATGAAAACGACTGAGATAC
TTTCAAAAGACAACCAAGTGAGCAGCACAGACTAATGAGTAGAATCAATAAGAACGTGGTTTTGGCCCTTTTAACGCTGACAAGTTCTGC
ATTTCTGCTGTTTCAGTTGTACTACTACAAGCACTATTTATCAACAAAGAATGGAGCTGGTTTGTCAAAATCCAAAGGAAGCCGAATTGG
ATTTGATAGCACACAGTGGGGTTTTGTCTCCACAATTATCCGTTTACTTGACAGCCCCTCAACATGCATTAGAGCAAAAGCCTTCCTGGT
TCTTCTATATATTTTGATTTATAACCGTGAGATGTTGCTGCTCAGTTGCCAAGCAAGACTGGTGATGTACATCGAGAGAGACAGCAGAAA
GACCACTCCAGGCAAGGAGCAGCAAAGTGGCAATGAATACCTGTCCAAATGCCTGGATCTTCTCATCTGTCACATTGTGCAGGAGCTGCC
ACGAATCCTGGGTGACATTCTTAACTCCTTGGCTAATGTTTCTGGACGTAAACACCCATCAACAGTTCAAGTGAAACAGCTGAAGTTGTG
TCTCCCCCTGATGCCTGTAGTGCTTCACCTCGTAACTTCACAGGTATTTCGACCTCAAGTTGTGACAGAAGAGTTTCTTTTCAGCTATGG
AACTATTCTTAGTCATATTAAATCTGTAGACTCAGGAGAAACGAACATAGATGGAGCCATAGGACTGACAGCATCAGAAGAATTTATCAA
GATCACATTGTCAGCTTTTGAAGCAATAATACAGTATCCTATTTTATTGAAAGACTATCGCTCCACGGTTGTTGACTATATACTGCCACC
CTTGGTGTCCTTGGTTCAAAGCCAAAATGTGGAGTGGAGACTCTTTAGCTTGCGGTTGCTCTCAGAAACCACATCTCTACTCGTGAACCA
GGAGTTTGGGGATGGCAAGGAGAAGGCCAGTGTTGATTCTGACAGCAATCTTCTGGCTCTCATTCGAGATGTCTTACTTCCCCAGTATGA
GCACATTCTTTTAGAACCTGACCCAGTACCAGCATATGCTCTGAAACTGCTAGTCGCGATGACTGAACACAACCCAACTTTCACAAGACT
TGTGGAAGAAAGCAAACTGATCCCACTCATTTTTGAAGTAACTCTGGAACATCAGGAGAGCATTCTGGGTAATACCATGCAAAGTGTGAT
TGCATTACTCAGCAATCTAGTTGCCTGCAAAGATTCGAATATGGAACTACTTTATGAACAAGGACTTGTCAGTCACATCTGTAACCTGCT
CACTGAAACTGCCACACTGTGCTTGGATGTGGACAATAAAAACAACAATGAGATGGCAGCTCCACTGCTCTTTTCCCTGCTTGATATTTT
GCACAGCATGCTGACCTATACCTCCGGTATTGTACGGCTGGCTTTGCAGGCCCAGAAGTCTGGCTCAGGAGAGGACCCTCAGGCTGCAGA
AGACCTGCTGCTGCTCAACAGACCTCTGACAGACCTGATTAGCCTGCTCATTCCACTGCTTCCTAATGAAGATCCTGAGATTTTTGATGT
TTCATCCAAGTGCCTGTCTATACTGGTTCAGCTGTATGGAGGGGAAAACCCGGACAGCCTCTCTCCTGAAAATGTGGAAATTTTTGCTCA
TTTACTGACATCCAAGGAGGACCCAAAGGAGCAGAAGCTTCTGTTAAGGATTCTCAGAAGAATGATCACCTCCAATGAGAAGCACTTGGA
GAGCCTCAAGAATGCAGGCAGCCTCCTGCGGGCTCTGGAGCGGCTGGCCCCTGGGAGTGGTTCATTTGCCGACAGTGCGGTGGCTCCCTT
GGCCCTGGAAATCCTCCAAGCCGTTGGGCACTAGGCAAGAAGGTGCTTAGCACAAGCCCGCCCTGTGGCCCCAGCCCTCGGATGCATAAG
CAAGGTCAGCTCCCAGACACCTTTGCCACATCCCCTCACAGCTGTCTTTGGACCTAATAAAGTCAGCTTAACCCAGAACCTGGTGGCCCA
AGTGCTCACTAACCCCAGGGCCTAGAAAACTGACTCAGAATGGACTTCCTTGGTTCCTGTGGAATGCATCTGGGAAGCCCAGGTTTGTTA

>30551_30551_3_FKTN-ULK4_FKTN_chr9_108358938_ENST00000448551_ULK4_chr3_41795980_ENST00000301831_length(amino acids)=599AA_BP=55
MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSTKNGAGLSKSKGSRIGFDSTQWGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREM
LLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLV
TSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVE
WRLFSLRLLSETTSLLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIF
EVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIV
RLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQ

--------------------------------------------------------------
>30551_30551_4_FKTN-ULK4_FKTN_chr9_108358938_ENST00000540160_ULK4_chr3_41795980_ENST00000301831_length(transcript)=2244nt_BP=287nt
AAAGCGGAGCGGCTGCAGCCTGCTGTTGAGTGAGAAAACAAAATTATCTTCCTTTCCAAATCCAAAAAGATGAAAACGACTGAGATACTT
TCAAAAGACAACCAAGTGAGCAGCACAGACTAATGAGTAGAATCAATAAGAACGTGGTTTTGGCCCTTTTAACGCTGACAAGTTCTGCAT
TTCTGCTGTTTCAGTTGTACTACTACAAGCACTATTTATCAACAAAGAATGGAGCTGGTTTGTCAAAATCCAAAGGAAGCCGAATTGGAT
TTGATAGCACACAGTGGGGTTTTGTCTCCACAATTATCCGTTTACTTGACAGCCCCTCAACATGCATTAGAGCAAAAGCCTTCCTGGTTC
TTCTATATATTTTGATTTATAACCGTGAGATGTTGCTGCTCAGTTGCCAAGCAAGACTGGTGATGTACATCGAGAGAGACAGCAGAAAGA
CCACTCCAGGCAAGGAGCAGCAAAGTGGCAATGAATACCTGTCCAAATGCCTGGATCTTCTCATCTGTCACATTGTGCAGGAGCTGCCAC
GAATCCTGGGTGACATTCTTAACTCCTTGGCTAATGTTTCTGGACGTAAACACCCATCAACAGTTCAAGTGAAACAGCTGAAGTTGTGTC
TCCCCCTGATGCCTGTAGTGCTTCACCTCGTAACTTCACAGGTATTTCGACCTCAAGTTGTGACAGAAGAGTTTCTTTTCAGCTATGGAA
CTATTCTTAGTCATATTAAATCTGTAGACTCAGGAGAAACGAACATAGATGGAGCCATAGGACTGACAGCATCAGAAGAATTTATCAAGA
TCACATTGTCAGCTTTTGAAGCAATAATACAGTATCCTATTTTATTGAAAGACTATCGCTCCACGGTTGTTGACTATATACTGCCACCCT
TGGTGTCCTTGGTTCAAAGCCAAAATGTGGAGTGGAGACTCTTTAGCTTGCGGTTGCTCTCAGAAACCACATCTCTACTCGTGAACCAGG
AGTTTGGGGATGGCAAGGAGAAGGCCAGTGTTGATTCTGACAGCAATCTTCTGGCTCTCATTCGAGATGTCTTACTTCCCCAGTATGAGC
ACATTCTTTTAGAACCTGACCCAGTACCAGCATATGCTCTGAAACTGCTAGTCGCGATGACTGAACACAACCCAACTTTCACAAGACTTG
TGGAAGAAAGCAAACTGATCCCACTCATTTTTGAAGTAACTCTGGAACATCAGGAGAGCATTCTGGGTAATACCATGCAAAGTGTGATTG
CATTACTCAGCAATCTAGTTGCCTGCAAAGATTCGAATATGGAACTACTTTATGAACAAGGACTTGTCAGTCACATCTGTAACCTGCTCA
CTGAAACTGCCACACTGTGCTTGGATGTGGACAATAAAAACAACAATGAGATGGCAGCTCCACTGCTCTTTTCCCTGCTTGATATTTTGC
ACAGCATGCTGACCTATACCTCCGGTATTGTACGGCTGGCTTTGCAGGCCCAGAAGTCTGGCTCAGGAGAGGACCCTCAGGCTGCAGAAG
ACCTGCTGCTGCTCAACAGACCTCTGACAGACCTGATTAGCCTGCTCATTCCACTGCTTCCTAATGAAGATCCTGAGATTTTTGATGTTT
CATCCAAGTGCCTGTCTATACTGGTTCAGCTGTATGGAGGGGAAAACCCGGACAGCCTCTCTCCTGAAAATGTGGAAATTTTTGCTCATT
TACTGACATCCAAGGAGGACCCAAAGGAGCAGAAGCTTCTGTTAAGGATTCTCAGAAGAATGATCACCTCCAATGAGAAGCACTTGGAGA
GCCTCAAGAATGCAGGCAGCCTCCTGCGGGCTCTGGAGCGGCTGGCCCCTGGGAGTGGTTCATTTGCCGACAGTGCGGTGGCTCCCTTGG
CCCTGGAAATCCTCCAAGCCGTTGGGCACTAGGCAAGAAGGTGCTTAGCACAAGCCCGCCCTGTGGCCCCAGCCCTCGGATGCATAAGCA
AGGTCAGCTCCCAGACACCTTTGCCACATCCCCTCACAGCTGTCTTTGGACCTAATAAAGTCAGCTTAACCCAGAACCTGGTGGCCCAAG
TGCTCACTAACCCCAGGGCCTAGAAAACTGACTCAGAATGGACTTCCTTGGTTCCTGTGGAATGCATCTGGGAAGCCCAGGTTTGTTAGC

>30551_30551_4_FKTN-ULK4_FKTN_chr9_108358938_ENST00000540160_ULK4_chr3_41795980_ENST00000301831_length(amino acids)=599AA_BP=55
MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSTKNGAGLSKSKGSRIGFDSTQWGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREM
LLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLV
TSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVE
WRLFSLRLLSETTSLLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIF
EVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIV
RLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQ

--------------------------------------------------------------
>30551_30551_5_FKTN-ULK4_FKTN_chr9_108358938_ENST00000602661_ULK4_chr3_41795980_ENST00000301831_length(transcript)=2338nt_BP=381nt
GTAAAGCGGAGCGGCTGCAGCCTGCTGTTGAGTGAGATTGAAAGGAAACACACTGAATGAGGAAAAACTAACATACGGTCATCAACATCC
TTGTATAACCTAGTTTTTAAAAAAATTGGATTTCAAAGAAAACAAAATTATCTTCCTTTCCAAATCCAAAAAGATGAAAACGACTGAGAT
ACTTTCAAAAGACAACCAAGTGAGCAGCACAGACTAATGAGTAGAATCAATAAGAACGTGGTTTTGGCCCTTTTAACGCTGACAAGTTCT
GCATTTCTGCTGTTTCAGTTGTACTACTACAAGCACTATTTATCAACAAAGAATGGAGCTGGTTTGTCAAAATCCAAAGGAAGCCGAATT
GGATTTGATAGCACACAGTGGGGTTTTGTCTCCACAATTATCCGTTTACTTGACAGCCCCTCAACATGCATTAGAGCAAAAGCCTTCCTG
GTTCTTCTATATATTTTGATTTATAACCGTGAGATGTTGCTGCTCAGTTGCCAAGCAAGACTGGTGATGTACATCGAGAGAGACAGCAGA
AAGACCACTCCAGGCAAGGAGCAGCAAAGTGGCAATGAATACCTGTCCAAATGCCTGGATCTTCTCATCTGTCACATTGTGCAGGAGCTG
CCACGAATCCTGGGTGACATTCTTAACTCCTTGGCTAATGTTTCTGGACGTAAACACCCATCAACAGTTCAAGTGAAACAGCTGAAGTTG
TGTCTCCCCCTGATGCCTGTAGTGCTTCACCTCGTAACTTCACAGGTATTTCGACCTCAAGTTGTGACAGAAGAGTTTCTTTTCAGCTAT
GGAACTATTCTTAGTCATATTAAATCTGTAGACTCAGGAGAAACGAACATAGATGGAGCCATAGGACTGACAGCATCAGAAGAATTTATC
AAGATCACATTGTCAGCTTTTGAAGCAATAATACAGTATCCTATTTTATTGAAAGACTATCGCTCCACGGTTGTTGACTATATACTGCCA
CCCTTGGTGTCCTTGGTTCAAAGCCAAAATGTGGAGTGGAGACTCTTTAGCTTGCGGTTGCTCTCAGAAACCACATCTCTACTCGTGAAC
CAGGAGTTTGGGGATGGCAAGGAGAAGGCCAGTGTTGATTCTGACAGCAATCTTCTGGCTCTCATTCGAGATGTCTTACTTCCCCAGTAT
GAGCACATTCTTTTAGAACCTGACCCAGTACCAGCATATGCTCTGAAACTGCTAGTCGCGATGACTGAACACAACCCAACTTTCACAAGA
CTTGTGGAAGAAAGCAAACTGATCCCACTCATTTTTGAAGTAACTCTGGAACATCAGGAGAGCATTCTGGGTAATACCATGCAAAGTGTG
ATTGCATTACTCAGCAATCTAGTTGCCTGCAAAGATTCGAATATGGAACTACTTTATGAACAAGGACTTGTCAGTCACATCTGTAACCTG
CTCACTGAAACTGCCACACTGTGCTTGGATGTGGACAATAAAAACAACAATGAGATGGCAGCTCCACTGCTCTTTTCCCTGCTTGATATT
TTGCACAGCATGCTGACCTATACCTCCGGTATTGTACGGCTGGCTTTGCAGGCCCAGAAGTCTGGCTCAGGAGAGGACCCTCAGGCTGCA
GAAGACCTGCTGCTGCTCAACAGACCTCTGACAGACCTGATTAGCCTGCTCATTCCACTGCTTCCTAATGAAGATCCTGAGATTTTTGAT
GTTTCATCCAAGTGCCTGTCTATACTGGTTCAGCTGTATGGAGGGGAAAACCCGGACAGCCTCTCTCCTGAAAATGTGGAAATTTTTGCT
CATTTACTGACATCCAAGGAGGACCCAAAGGAGCAGAAGCTTCTGTTAAGGATTCTCAGAAGAATGATCACCTCCAATGAGAAGCACTTG
GAGAGCCTCAAGAATGCAGGCAGCCTCCTGCGGGCTCTGGAGCGGCTGGCCCCTGGGAGTGGTTCATTTGCCGACAGTGCGGTGGCTCCC
TTGGCCCTGGAAATCCTCCAAGCCGTTGGGCACTAGGCAAGAAGGTGCTTAGCACAAGCCCGCCCTGTGGCCCCAGCCCTCGGATGCATA
AGCAAGGTCAGCTCCCAGACACCTTTGCCACATCCCCTCACAGCTGTCTTTGGACCTAATAAAGTCAGCTTAACCCAGAACCTGGTGGCC
CAAGTGCTCACTAACCCCAGGGCCTAGAAAACTGACTCAGAATGGACTTCCTTGGTTCCTGTGGAATGCATCTGGGAAGCCCAGGTTTGT

>30551_30551_5_FKTN-ULK4_FKTN_chr9_108358938_ENST00000602661_ULK4_chr3_41795980_ENST00000301831_length(amino acids)=599AA_BP=55
MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSTKNGAGLSKSKGSRIGFDSTQWGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREM
LLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLV
TSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVE
WRLFSLRLLSETTSLLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIF
EVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIV
RLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQ

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for FKTN-ULK4

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for FKTN-ULK4

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for FKTN-ULK4

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source