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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AHI1-CHEK2 (FusionGDB2 ID:3092)

Fusion Gene Summary for AHI1-CHEK2

check button Fusion gene summary
Fusion gene informationFusion gene name: AHI1-CHEK2
Fusion gene ID: 3092
HgeneTgene
Gene symbol

AHI1

CHEK2

Gene ID

54806

11200

Gene nameAbelson helper integration site 1checkpoint kinase 2
SynonymsAHI-1|JBTS3|ORF1|dJ71N10.1CDS1|CHK2|HuCds1|LFS2|PP1425|RAD53|hCds1
Cytomap

6q23.3

22q12.1

Type of geneprotein-codingprotein-coding
Descriptionjouberinabelson helper integration site 1 protein homologcontatins SH3 and WD40 domainsserine/threonine-protein kinase Chk2CHK2 checkpoint homologcds1 homologcheckpoint-like protein CHK2
Modification date2020031320200320
UniProtAcc.

O96017

Ensembl transtripts involved in fusion geneENST00000367800, ENST00000417892, 
ENST00000457866, ENST00000327035, 
ENST00000367798, ENST00000488690, 
ENST00000528103, ENST00000531527, 
ENST00000534469, 		ENST00000328354, 
ENST00000382580, ENST00000402731, 
ENST00000404276, ENST00000405598, 
ENST00000544772, ENST00000348295, 
ENST00000382565, ENST00000382566, 
ENST00000382578, ENST00000403642, 
ENST00000464581, 
Fusion gene scores* DoF score10 X 11 X 6=6606 X 5 X 5=150
# samples 107
** MAII scorelog2(10/660*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/150*10)=-1.09953567355091
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AHI1 [Title/Abstract] AND CHEK2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAHI1(135644300)-CHEK2(29121355), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCHEK2

GO:0006355

regulation of transcription, DNA-templated

12717439

TgeneCHEK2

GO:0006468

protein phosphorylation

12717439

TgeneCHEK2

GO:0006974

cellular response to DNA damage stimulus

24550317

TgeneCHEK2

GO:0008630

intrinsic apoptotic signaling pathway in response to DNA damage

12402044

TgeneCHEK2

GO:0042770

signal transduction in response to DNA damage

14744935

TgeneCHEK2

GO:0045893

positive regulation of transcription, DNA-templated

17101782

TgeneCHEK2

GO:0046777

protein autophosphorylation

16794575|18644861

TgeneCHEK2

GO:0050821

protein stabilization

12717439


check buttonFusion gene breakpoints across AHI1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across CHEK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-EW-A1IX-01AAHI1chr6

135644300

-CHEK2chr22

29121355

-


Top

Fusion Gene ORF analysis for AHI1-CHEK2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000367800ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000367800ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000367800ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000367800ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000367800ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000367800ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000417892ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000417892ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000417892ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000417892ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000417892ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000417892ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000457866ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000457866ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000457866ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000457866ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000457866ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-5UTRENST00000457866ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000367800ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000367800ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000367800ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000367800ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000367800ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000367800ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000417892ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000417892ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000417892ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000417892ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000417892ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000417892ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000457866ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000457866ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000457866ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000457866ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000457866ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
5CDS-intronENST00000457866ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000327035ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000327035ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000327035ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000327035ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000327035ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000327035ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000367798ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000367798ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000367798ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000367798ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000367798ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000367798ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000488690ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000488690ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000488690ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000488690ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000488690ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000488690ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000528103ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000528103ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000528103ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000528103ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000528103ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000528103ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000531527ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000531527ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000531527ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000531527ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000531527ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000531527ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000534469ENST00000328354AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000534469ENST00000382580AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000534469ENST00000402731AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000534469ENST00000404276AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000534469ENST00000405598AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-5UTRENST00000534469ENST00000544772AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000327035ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000327035ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000327035ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000327035ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000327035ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000327035ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000367798ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000367798ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000367798ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000367798ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000367798ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000367798ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000488690ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000488690ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000488690ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000488690ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000488690ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000488690ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000528103ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000528103ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000528103ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000528103ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000528103ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000528103ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000531527ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000531527ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000531527ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000531527ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000531527ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000531527ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000534469ENST00000348295AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000534469ENST00000382565AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000534469ENST00000382566AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000534469ENST00000382578AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000534469ENST00000403642AHI1chr6

135644300

-CHEK2chr22

29121355

-
intron-intronENST00000534469ENST00000464581AHI1chr6

135644300

-CHEK2chr22

29121355

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for AHI1-CHEK2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AHI1-CHEK2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:135644300/:29121355)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CHEK2

O96017

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Regulates cell cycle checkpoint arrest through phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. Regulates DNA repair through phosphorylation of BRCA2, enhancing the association of RAD51 with chromatin which promotes DNA repair by homologous recombination. Also stimulates the transcription of genes involved in DNA repair (including BRCA2) through the phosphorylation and activation of the transcription factor FOXM1. Regulates apoptosis through the phosphorylation of p53/TP53, MDM4 and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may alleviate inhibition by MDM2, leading to accumulation of active p53/TP53. Phosphorylation of MDM4 may also reduce degradation of p53/TP53. Also controls the transcription of pro-apoptotic genes through phosphorylation of the transcription factor E2F1. Tumor suppressor, it may also have a DNA damage-independent function in mitotic spindle assembly by phosphorylating BRCA1. Its absence may be a cause of the chromosomal instability observed in some cancer cells. Promotes the CCAR2-SIRT1 association and is required for CCAR2-mediated SIRT1 inhibition (PubMed:25361978). {ECO:0000250|UniProtKB:Q9Z265, ECO:0000269|PubMed:10097108, ECO:0000269|PubMed:10724175, ECO:0000269|PubMed:11298456, ECO:0000269|PubMed:12402044, ECO:0000269|PubMed:12607004, ECO:0000269|PubMed:12717439, ECO:0000269|PubMed:12810724, ECO:0000269|PubMed:16163388, ECO:0000269|PubMed:17101782, ECO:0000269|PubMed:17380128, ECO:0000269|PubMed:17715138, ECO:0000269|PubMed:18317453, ECO:0000269|PubMed:18644861, ECO:0000269|PubMed:18728393, ECO:0000269|PubMed:20364141, ECO:0000269|PubMed:25361978, ECO:0000269|PubMed:25619829, ECO:0000269|PubMed:9836640, ECO:0000269|PubMed:9889122}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for AHI1-CHEK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for AHI1-CHEK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AHI1-CHEK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AHI1-CHEK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource