FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:FOCAD-FBXO10 (FusionGDB2 ID:30997)

Fusion Gene Summary for FOCAD-FBXO10

check button Fusion gene summary
Fusion gene informationFusion gene name: FOCAD-FBXO10
Fusion gene ID: 30997
HgeneTgene
Gene symbol

FOCAD

FBXO10

Gene ID

54914

26267

Gene namefocadhesinF-box protein 10
SynonymsKIAA1797FBX10|PRMT11
Cytomap

9p21.3

9p13.2

Type of geneprotein-codingprotein-coding
DescriptionfocadhesinF-box only protein 10F-box protein Fbx10
Modification date2020031320200313
UniProtAcc

Q5VW36

Q9UK96

Ensembl transtripts involved in fusion geneENST00000338382, ENST00000380249, 
ENST00000605086, ENST00000604828, 
ENST00000543968, ENST00000432825, 
ENST00000541829, 
Fusion gene scores* DoF score16 X 12 X 11=21122 X 2 X 2=8
# samples 172
** MAII scorelog2(17/2112*10)=-3.63500318322075
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: FOCAD [Title/Abstract] AND FBXO10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFOCAD(20885229)-FBXO10(37529257), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across FOCAD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FBXO10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-09-2054-01AFOCADchr9

20885229

+FBXO10chr9

37529257

-


Top

Fusion Gene ORF analysis for FOCAD-FBXO10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000338382ENST00000543968FOCADchr9

20885229

+FBXO10chr9

37529257

-
5CDS-5UTRENST00000380249ENST00000543968FOCADchr9

20885229

+FBXO10chr9

37529257

-
5CDS-5UTRENST00000605086ENST00000543968FOCADchr9

20885229

+FBXO10chr9

37529257

-
In-frameENST00000338382ENST00000432825FOCADchr9

20885229

+FBXO10chr9

37529257

-
In-frameENST00000338382ENST00000541829FOCADchr9

20885229

+FBXO10chr9

37529257

-
In-frameENST00000380249ENST00000432825FOCADchr9

20885229

+FBXO10chr9

37529257

-
In-frameENST00000380249ENST00000541829FOCADchr9

20885229

+FBXO10chr9

37529257

-
In-frameENST00000605086ENST00000432825FOCADchr9

20885229

+FBXO10chr9

37529257

-
In-frameENST00000605086ENST00000541829FOCADchr9

20885229

+FBXO10chr9

37529257

-
intron-3CDSENST00000604828ENST00000432825FOCADchr9

20885229

+FBXO10chr9

37529257

-
intron-3CDSENST00000604828ENST00000541829FOCADchr9

20885229

+FBXO10chr9

37529257

-
intron-5UTRENST00000604828ENST00000543968FOCADchr9

20885229

+FBXO10chr9

37529257

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000380249FOCADchr920885229+ENST00000432825FBXO10chr937529257-5946298923242901352
ENST00000380249FOCADchr920885229+ENST00000541829FBXO10chr937529257-4291298923242901353
ENST00000338382FOCADchr920885229+ENST00000432825FBXO10chr937529257-55822625039261308
ENST00000338382FOCADchr920885229+ENST00000541829FBXO10chr937529257-39272625039261308
ENST00000605086FOCADchr920885229+ENST00000432825FBXO10chr937529257-40521095992396765
ENST00000605086FOCADchr920885229+ENST00000541829FBXO10chr937529257-23971095992396765

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000380249ENST00000432825FOCADchr920885229+FBXO10chr937529257-0.0011105640.9988895
ENST00000380249ENST00000541829FOCADchr920885229+FBXO10chr937529257-0.0014933530.9985066
ENST00000338382ENST00000432825FOCADchr920885229+FBXO10chr937529257-0.0006429320.99935704
ENST00000338382ENST00000541829FOCADchr920885229+FBXO10chr937529257-0.000913550.9990865
ENST00000605086ENST00000432825FOCADchr920885229+FBXO10chr937529257-0.0066222710.99337775
ENST00000605086ENST00000541829FOCADchr920885229+FBXO10chr937529257-0.0050763850.99492365

Top

Fusion Genomic Features for FOCAD-FBXO10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for FOCAD-FBXO10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:20885229/chr9:37529257)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FOCAD

Q5VW36

FBXO10

Q9UK96

FUNCTION: Potential tumor suppressor in gliomas. {ECO:0000250, ECO:0000269|PubMed:22427331}.FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2. {ECO:0000269|PubMed:23431138}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOCADchr9:20885229chr9:37529257ENST00000338382+2043404_4248751802.0TransmembraneHelical
HgeneFOCADchr9:20885229chr9:37529257ENST00000338382+2043441_4618751802.0TransmembraneHelical
HgeneFOCADchr9:20885229chr9:37529257ENST00000380249+2346404_4248751802.0TransmembraneHelical
HgeneFOCADchr9:20885229chr9:37529257ENST00000380249+2346441_4618751802.0TransmembraneHelical
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311538_560523957.0RepeatNote=PbH1 7
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311561_583523957.0RepeatNote=PbH1 8
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311584_606523957.0RepeatNote=PbH1 9
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311607_629523957.0RepeatNote=PbH1 10
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311630_652523957.0RepeatNote=PbH1 11
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311653_675523957.0RepeatNote=PbH1 12
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311717_739523957.0RepeatNote=PbH1 13
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311740_762523957.0RepeatNote=PbH1 14
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311764_786523957.0RepeatNote=PbH1 15
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311787_809523957.0RepeatNote=PbH1 16
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311832_854523957.0RepeatNote=PbH1 17

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOCADchr9:20885229chr9:37529257ENST00000338382+20431036_10568751802.0TransmembraneHelical
HgeneFOCADchr9:20885229chr9:37529257ENST00000380249+23461036_10568751802.0TransmembraneHelical
TgeneFBXO10chr9:20885229chr9:37529257ENST000004328253111_48523957.0DomainF-box
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311198_217523957.0RepeatNote=PbH1 1
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311238_260523957.0RepeatNote=PbH1 2
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311427_448523957.0RepeatNote=PbH1 3
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311449_470523957.0RepeatNote=PbH1 4
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311471_493523957.0RepeatNote=PbH1 5
TgeneFBXO10chr9:20885229chr9:37529257ENST00000432825311494_516523957.0RepeatNote=PbH1 6


Top

Fusion Gene Sequence for FOCAD-FBXO10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>30997_30997_1_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000338382_FBXO10_chr9_37529257_ENST00000432825_length(transcript)=5582nt_BP=2625nt
ATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCTAAAG
GAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAATGTA
GTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACTCAAC
TTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGGTGGG
GAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCCAGTG
TTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTGGTAT
CTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTGTGAC
AAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACAGACA
ACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAGTCTT
CAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACTTCTG
AAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTTAAAT
CTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACTATCT
TCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACAGCAG
GAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTGGAGG
ATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCCTGCG
CCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGCCCAA
GCAGATTCCTCCCAGGTGCCAAATCTGATTCCAGTTTTGATGTTCAAATTGGGAAGACCACTGGAACCTATATTATATAATGATATATTG
TATACTTTACCTAAGCTTGGTGTTCACAAGGTGTGTATAGGACAAATTCTACGAATAATACAACTACTTGGAACCACACCACGACTAAGA
GCTGTCACTTTGCGCTTGCTGACATCTTTGTGGGAAAAGCAGGACCGAGTCTATCCTGAACTGCAGCGTTTCATGGCTGTGTCTGATGTA
CCTTCTCTTTCGGTGGGCAAGGAAGTCCAATGGGAGAAACTGATTGCAAAAGCAGCATCAATCAGAGATATATGTAAGCAGAGGCCATAT
CAACATGGTGCAGATATGTTGGCAGCTATTTCTCAAGTGTTGAATGAATGCACCAAGCCTGATCAAGCTACTCCAGCAGCCTTGGTATTA
CAGGGTCTTCATGCACTCTGTCAAGCTGAGGTTGTTTGCATTCGCTCCACTTGGAATGCTCTCTCTCCAAAGCTGAGTTGTGACACAAGA
CCTCTCATTCTGAAGACACTGAGTGAACTATTTTCTCTAGTTCCTTCCTTAACGGTCAATACAACTGAATATGAGAATTTTAAAGTTCAA
GTCCTCAGCTTCCTCTGGACTCATACTCAAAACAAGGACCCAATTGTAGCAAATGCTGCATATAGATCCCTGGCCAACTTTACTGCAGGA
GAACACACCATTCTTCATCTGCCTGAAAAGATAAGACCAGAAATTCCCATTCCTGAAGAGTTAGATGACGATGAAGATGTTGAGGATGTG
GATCTTTCAGTTCCTGGCTCTTGCTATCTCAAACTGTTGTCACTCACTCCCCCTTTGGTTTTACCAGCTTTGGAGGAATTTTTTACATCA
CTTGTGAAGCAAGAAATGGTGAATATGCCTCGTGGGATATATCACTCTGCATTAAAAGGAGGTGCCCGCTCAGACCAAGGAAAGACTGTA
GCAGGAATCCCCAATTTTATATTGAAAATGTATGAAACAAACAAGCAACCAGGACTGAAACCTGGCCTTGCAGGTGGTATGTTATTTTGC
TATGATGTTTCCATGTATCAGAGTAAAGATGGAAAACCATTGAACAGACTGATGGCCAGCAGAGGGCGAAGTTTCAAGCAGACTTCACTT
GCTCTTGTACATGAGTGTAACCAGATCCACCATGGCCTTCGCTCTGGCATTGTCGTCCTTGGCAATGGGAAAGGCATCATCCGGAACAAT
CAAATCTTTTCCAATAAGGAGGCTGGCATTTACATCCTGTACCACGGAAACCCCGTTGTGAGCGGGAACCACATCTTCAAGGGCCGTGCT
GCCGGCATAGCAGTGAATGAGAACGGCAAAGGCCTCATCACAGAAAATGTCATCCGTGAGAATCAGTGGGGAGGTGTGGACATCCGCCGT
GGAGGGATCCCCGTTCTCAGGAGTAACCTCATCTGCTTTGGCTATTCAGATGGTGTGGTTGTGGGAGACGAAGGCAAAGGCCTCATAGAA
GGAAATACCATCTACGCTAACAAGGGCTGTGGTGTGTGGATGATGTCGTCCAGCCTCCCCCATGTCACCAGCAACCACGTCAGCTACAAT
GGCCTGTATGGAGTGGCAGTATTTAGCCAGAAGGATGGCTCCAGCGAGTTACCTCGAGGCCACAGGGCTCAAGAGAACTTCAGCGAGGAT
GGGGACGCCATCCTCTGGGAGACAGAGCTGGAGAAGGAGGACGACCCACTGCGCCGGCCCATCACCATAGCTCTTGTTGAGTCTAACAGT
ATTAATCACAATGGAGCCTCAGGACTCTATGTCCAGAGCAGCGAGGCACTGCATGTCATCACCAATGTGATCCACGCGAATGGGGACAGA
GGCATTACTGTGGCCCAGAGCAGCCAACCCACCCGAGTGGCCAACAACAGCATCTCCTGCAACCGGCAAAGTGGGGTCAAGGTTGAGGCC
CAGTGCAAAGTGGAGCTCCGGGGCAATGGTATCTATGACAACAGAGGCCACGGCATTATCACCAAGGGCGACAGCACCATCGTCATTGAA
AACGATATCATTGGCAACCGGGGCAGCGGGCTGCAGCTGCTGCCCAGGTCCGACACTAAAGTAATAAAGAACCGGATCCACTCGTTCCGG
GCCTACGGCATCGCCGTGCGGGGCCGTGCCAAGGCCCTGGTGCAGGAAAACATCATCTTCCAGGGCAAAACCAGTAAGACCATCTTTCAG
CAGATCTCAAACAACCGAGAATGCATCATGCAAAACAACAAGTTCCTGGTCTTCAAGAAAAAGTCTGATACGTGGCGCCTGGTGAACCCA
CCAGCACGGCCCCACCTTGAAAATTCTCTCAGACGTCCCTCGGCAGCCCACAATGGGCAGAAGGTGACAGCCATGGCAACGAGGATCACA
GCCCGGGTGGAAGGTGGTTACCACAGCAACCGCAGTGTCTTCTGCACCATCCTGTGAGGACACAGACCTGCTTCAGGGCCAAGCCTGGAT
GGGTGCTCAGAGGAGCTAAGGTGGAAATACTGCCTGAAAAGACTCCGCCCCTCCCCCTCCCCCTCGAACAAATGGGTCCCGGGCCTCCAA
AACACGGTACCTCCAGAACACTTCAGCTCCACAGCCCATAGCAAGAAGAAAGTGGGCAATGTTTTTCAGGGAGAAGGGATAGAAGCTGGT
GGGTTTCCAGTCACTCGAAGTCTATAAAGATTGTGAAGAGCGGGGGAAGCTCAAATGCTGAAGCTTTTGGTCAGGATTTTCTCTGAGTTC
TAAGGAACTGTGTTTTACACACACCAAACCCAGACTCTTCTCAGGAAAGAGCAGATTTACTTCTGATGGCGGGAAGTGATTCTAGTGAGG
TGGAGAGAGACAACTGCTCCAGAATTTTCCCCTTTGCTAGAGCTGTCTCCCTCTCAATCCCTCCAGGGACCCCACCACACCCTCCCAGCT
GTCTCTGGAGGCTGGAGGAGTTGAGTTTGGTTGACTTGAGGACTTGGACATGGACCTGGGAGGAAGGAAGGACCTGGGAGCAACAGGAGA
CCCCATGGAAAGGCTGCCCCAGGGATGACAAGAGGGACATGCTGAAACAGGTGGGGCTGCAGCGTGCAGGCAGATGCTAGGCTGGGTGGG
CAGGGATGCACAAGGCTCTACTCCATCCCCAGAGAGCTCCCAAATGCAGAAGGATTCAAACCCCATGTGAGCGTGCCCACACCAGCCGCC
CCTCCTGAGCATCAGCCTGTTCAGATGAGGGTACCTGGGCCTCTCGTTCGCATCTGTGTTCTCATGGATGAGCGCTGGTCTTTACTGACC
CTCCCAAGCCTCCCCACTCTGTGCCTTGGCTCATGCTCTTTCCTCCTCCCGGCATGCCCTTCTCCCCCATCTCCGTGTCCTCGTTCCTCA
AGGTTTAGCCGAGACACTGCCACCTCCACATAGCTCTCCCTGCCCTCTTTCCCCCTCTGGGCCTCAGTGGCCTTTCTCTGCTCCCTCTCA
GGGTACTGAGCACTTTCTGCCTTGTCCTGGAGCTATCTGGGTCCATTGCCTGACCCCCCACTCACCTGTGTGCTCCCCGTAGGTAGGGCC
ACTTCTGACTGTGTGTCCCCAGATCCAGCCTGGGGTTGGGGTAGGATTAGTGGCCTGAGTGAGGAGAGGAAGGCCAGCTCCCAGAGGACT
TTACTGAACCGTACTGTGAATATGTCCAAGTCCCAAAGCCAGGTGAGGTCAGACCCCACTGCCTGAGGAAGAGGGCTGGATGCAGGGCCA
GCTCAACCTGAACAATCCCCTCCCACTCGGCCTTTCCTGTGGGGCCTTCACCAGCCTGCTGGGGTCACTGTCGTGCACTTGGCTGCGTGG
CTGGTTCTATTGGCCCTAGGTGCTGCTCTGTTGGGTGGGATGGGAGGGGGTAGAGGGAGCCAGGAGCACTGGGTTCTCCCTGAGAACACT
GGGCACAAGAGTACTGGCCTCTTCTATCCCTGGCACTGTCCTTTGCACTTGTTTGGTGGCCCCAATGTGAGTCGCTGTAAAAAATGCTGC
CGTTACTATTTTCTAAGAAATGACTTTTCTGTGAACCAACAGTAACAAAAACCTCAGTAACCAAAATAAAGTTCTATATTTTAAAAAAGG

>30997_30997_1_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000338382_FBXO10_chr9_37529257_ENST00000432825_length(amino acids)=1308AA_BP=875
MSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILN
LIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHPLITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWY
LYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCCDIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSL
QLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALLLLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILS
STALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVCPVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPA
PAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLEPILYNDILYTLPKLGVHKVCIGQILRIIQLLGTTPRLR
AVTLRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVL
QGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFTAG
EHTILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLTPPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTV
AGIPNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNRLMASRGRSFKQTSLALVHECNQIHHGLRSGIVVLGNGKGIIRNN
QIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIE
GNTIYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNS
INHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIE
NDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNP

--------------------------------------------------------------
>30997_30997_2_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000338382_FBXO10_chr9_37529257_ENST00000541829_length(transcript)=3927nt_BP=2625nt
ATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCTAAAG
GAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAATGTA
GTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACTCAAC
TTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGGTGGG
GAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCCAGTG
TTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTGGTAT
CTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTGTGAC
AAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACAGACA
ACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAGTCTT
CAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACTTCTG
AAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTTAAAT
CTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACTATCT
TCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACAGCAG
GAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTGGAGG
ATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCCTGCG
CCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGCCCAA
GCAGATTCCTCCCAGGTGCCAAATCTGATTCCAGTTTTGATGTTCAAATTGGGAAGACCACTGGAACCTATATTATATAATGATATATTG
TATACTTTACCTAAGCTTGGTGTTCACAAGGTGTGTATAGGACAAATTCTACGAATAATACAACTACTTGGAACCACACCACGACTAAGA
GCTGTCACTTTGCGCTTGCTGACATCTTTGTGGGAAAAGCAGGACCGAGTCTATCCTGAACTGCAGCGTTTCATGGCTGTGTCTGATGTA
CCTTCTCTTTCGGTGGGCAAGGAAGTCCAATGGGAGAAACTGATTGCAAAAGCAGCATCAATCAGAGATATATGTAAGCAGAGGCCATAT
CAACATGGTGCAGATATGTTGGCAGCTATTTCTCAAGTGTTGAATGAATGCACCAAGCCTGATCAAGCTACTCCAGCAGCCTTGGTATTA
CAGGGTCTTCATGCACTCTGTCAAGCTGAGGTTGTTTGCATTCGCTCCACTTGGAATGCTCTCTCTCCAAAGCTGAGTTGTGACACAAGA
CCTCTCATTCTGAAGACACTGAGTGAACTATTTTCTCTAGTTCCTTCCTTAACGGTCAATACAACTGAATATGAGAATTTTAAAGTTCAA
GTCCTCAGCTTCCTCTGGACTCATACTCAAAACAAGGACCCAATTGTAGCAAATGCTGCATATAGATCCCTGGCCAACTTTACTGCAGGA
GAACACACCATTCTTCATCTGCCTGAAAAGATAAGACCAGAAATTCCCATTCCTGAAGAGTTAGATGACGATGAAGATGTTGAGGATGTG
GATCTTTCAGTTCCTGGCTCTTGCTATCTCAAACTGTTGTCACTCACTCCCCCTTTGGTTTTACCAGCTTTGGAGGAATTTTTTACATCA
CTTGTGAAGCAAGAAATGGTGAATATGCCTCGTGGGATATATCACTCTGCATTAAAAGGAGGTGCCCGCTCAGACCAAGGAAAGACTGTA
GCAGGAATCCCCAATTTTATATTGAAAATGTATGAAACAAACAAGCAACCAGGACTGAAACCTGGCCTTGCAGGTGGTATGTTATTTTGC
TATGATGTTTCCATGTATCAGAGTAAAGATGGAAAACCATTGAACAGACTGATGGCCAGCAGAGGGCGAAGTTTCAAGCAGACTTCACTT
GCTCTTGTACATGAGTGTAACCAGATCCACCATGGCCTTCGCTCTGGCATTGTCGTCCTTGGCAATGGGAAAGGCATCATCCGGAACAAT
CAAATCTTTTCCAATAAGGAGGCTGGCATTTACATCCTGTACCACGGAAACCCCGTTGTGAGCGGGAACCACATCTTCAAGGGCCGTGCT
GCCGGCATAGCAGTGAATGAGAACGGCAAAGGCCTCATCACAGAAAATGTCATCCGTGAGAATCAGTGGGGAGGTGTGGACATCCGCCGT
GGAGGGATCCCCGTTCTCAGGAGTAACCTCATCTGCTTTGGCTATTCAGATGGTGTGGTTGTGGGAGACGAAGGCAAAGGCCTCATAGAA
GGAAATACCATCTACGCTAACAAGGGCTGTGGTGTGTGGATGATGTCGTCCAGCCTCCCCCATGTCACCAGCAACCACGTCAGCTACAAT
GGCCTGTATGGAGTGGCAGTATTTAGCCAGAAGGATGGCTCCAGCGAGTTACCTCGAGGCCACAGGGCTCAAGAGAACTTCAGCGAGGAT
GGGGACGCCATCCTCTGGGAGACAGAGCTGGAGAAGGAGGACGACCCACTGCGCCGGCCCATCACCATAGCTCTTGTTGAGTCTAACAGT
ATTAATCACAATGGAGCCTCAGGACTCTATGTCCAGAGCAGCGAGGCACTGCATGTCATCACCAATGTGATCCACGCGAATGGGGACAGA
GGCATTACTGTGGCCCAGAGCAGCCAACCCACCCGAGTGGCCAACAACAGCATCTCCTGCAACCGGCAAAGTGGGGTCAAGGTTGAGGCC
CAGTGCAAAGTGGAGCTCCGGGGCAATGGTATCTATGACAACAGAGGCCACGGCATTATCACCAAGGGCGACAGCACCATCGTCATTGAA
AACGATATCATTGGCAACCGGGGCAGCGGGCTGCAGCTGCTGCCCAGGTCCGACACTAAAGTAATAAAGAACCGGATCCACTCGTTCCGG
GCCTACGGCATCGCCGTGCGGGGCCGTGCCAAGGCCCTGGTGCAGGAAAACATCATCTTCCAGGGCAAAACCAGTAAGACCATCTTTCAG
CAGATCTCAAACAACCGAGAATGCATCATGCAAAACAACAAGTTCCTGGTCTTCAAGAAAAAGTCTGATACGTGGCGCCTGGTGAACCCA
CCAGCACGGCCCCACCTTGAAAATTCTCTCAGACGTCCCTCGGCAGCCCACAATGGGCAGAAGGTGACAGCCATGGCAACGAGGATCACA

>30997_30997_2_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000338382_FBXO10_chr9_37529257_ENST00000541829_length(amino acids)=1308AA_BP=875
MSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILN
LIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHPLITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWY
LYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCCDIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSL
QLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALLLLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILS
STALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVCPVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPA
PAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLEPILYNDILYTLPKLGVHKVCIGQILRIIQLLGTTPRLR
AVTLRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVL
QGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFTAG
EHTILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLTPPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTV
AGIPNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNRLMASRGRSFKQTSLALVHECNQIHHGLRSGIVVLGNGKGIIRNN
QIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIE
GNTIYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNS
INHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIE
NDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNP

--------------------------------------------------------------
>30997_30997_3_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000380249_FBXO10_chr9_37529257_ENST00000432825_length(transcript)=5946nt_BP=2989nt
GTTCGAGCTTCCCGGCTGCTTTGTTTACCTAATCAAGCCTGGGCAATGGCGGGCGCCCCTCCCGCAGCCTCGCTGCCGCCTTGCAGGTTG
ATCTCAGACTGCTGTGCTAGCAATCAGTGAGACTCCGTGGGCGTAGGACTCTCCAAGCCAGTGAGATGAACTCGGTATCTCAGATGGAAA
TGCAGAAATCACCGTCTTCTCCATCGCTCACGCTGGGAGCTGTAGACCGGAGCTGTTCCTATTCGGCCATCTTTGCTCCTCCCTGCAACT
AACTCCATTCTTAATTGACCATCAAGGAAATTTCCATCCACACAGATTAGCAGTTGAAAATGAAGCTGCACACATACATGTAAGAGAAGC
AAAAATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCT
AAAGGAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAA
TGTAGTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACT
CAACTTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGG
TGGGGAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCC
AGTGTTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTG
GTATCTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTG
TGACAAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACA
GACAACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAG
TCTTCAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACT
TCTGAAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTT
AAATCTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACT
ATCTTCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACA
GCAGGAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTG
GAGGATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCC
TGCGCCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGC
CCAAGCAGATTCCTCCCAGGTGCCAAATCTGATTCCAGTTTTGATGTTCAAATTGGGAAGACCACTGGAACCTATATTATATAATGATAT
ATTGTATACTTTACCTAAGCTTGGTGTTCACAAGGTGTGTATAGGACAAATTCTACGAATAATACAACTACTTGGAACCACACCACGACT
AAGAGCTGTCACTTTGCGCTTGCTGACATCTTTGTGGGAAAAGCAGGACCGAGTCTATCCTGAACTGCAGCGTTTCATGGCTGTGTCTGA
TGTACCTTCTCTTTCGGTGGGCAAGGAAGTCCAATGGGAGAAACTGATTGCAAAAGCAGCATCAATCAGAGATATATGTAAGCAGAGGCC
ATATCAACATGGTGCAGATATGTTGGCAGCTATTTCTCAAGTGTTGAATGAATGCACCAAGCCTGATCAAGCTACTCCAGCAGCCTTGGT
ATTACAGGGTCTTCATGCACTCTGTCAAGCTGAGGTTGTTTGCATTCGCTCCACTTGGAATGCTCTCTCTCCAAAGCTGAGTTGTGACAC
AAGACCTCTCATTCTGAAGACACTGAGTGAACTATTTTCTCTAGTTCCTTCCTTAACGGTCAATACAACTGAATATGAGAATTTTAAAGT
TCAAGTCCTCAGCTTCCTCTGGACTCATACTCAAAACAAGGACCCAATTGTAGCAAATGCTGCATATAGATCCCTGGCCAACTTTACTGC
AGGAGAACACACCATTCTTCATCTGCCTGAAAAGATAAGACCAGAAATTCCCATTCCTGAAGAGTTAGATGACGATGAAGATGTTGAGGA
TGTGGATCTTTCAGTTCCTGGCTCTTGCTATCTCAAACTGTTGTCACTCACTCCCCCTTTGGTTTTACCAGCTTTGGAGGAATTTTTTAC
ATCACTTGTGAAGCAAGAAATGGTGAATATGCCTCGTGGGATATATCACTCTGCATTAAAAGGAGGTGCCCGCTCAGACCAAGGAAAGAC
TGTAGCAGGAATCCCCAATTTTATATTGAAAATGTATGAAACAAACAAGCAACCAGGACTGAAACCTGGCCTTGCAGGTGGTATGTTATT
TTGCTATGATGTTTCCATGTATCAGAGTAAAGATGGAAAACCATTGAACAGACTGATGGCCAGCAGAGGGCGAAGTTTCAAGCAGACTTC
ACTTGCTCTTGTACATGAGTGTAACCAGATCCACCATGGCCTTCGCTCTGGCATTGTCGTCCTTGGCAATGGGAAAGGCATCATCCGGAA
CAATCAAATCTTTTCCAATAAGGAGGCTGGCATTTACATCCTGTACCACGGAAACCCCGTTGTGAGCGGGAACCACATCTTCAAGGGCCG
TGCTGCCGGCATAGCAGTGAATGAGAACGGCAAAGGCCTCATCACAGAAAATGTCATCCGTGAGAATCAGTGGGGAGGTGTGGACATCCG
CCGTGGAGGGATCCCCGTTCTCAGGAGTAACCTCATCTGCTTTGGCTATTCAGATGGTGTGGTTGTGGGAGACGAAGGCAAAGGCCTCAT
AGAAGGAAATACCATCTACGCTAACAAGGGCTGTGGTGTGTGGATGATGTCGTCCAGCCTCCCCCATGTCACCAGCAACCACGTCAGCTA
CAATGGCCTGTATGGAGTGGCAGTATTTAGCCAGAAGGATGGCTCCAGCGAGTTACCTCGAGGCCACAGGGCTCAAGAGAACTTCAGCGA
GGATGGGGACGCCATCCTCTGGGAGACAGAGCTGGAGAAGGAGGACGACCCACTGCGCCGGCCCATCACCATAGCTCTTGTTGAGTCTAA
CAGTATTAATCACAATGGAGCCTCAGGACTCTATGTCCAGAGCAGCGAGGCACTGCATGTCATCACCAATGTGATCCACGCGAATGGGGA
CAGAGGCATTACTGTGGCCCAGAGCAGCCAACCCACCCGAGTGGCCAACAACAGCATCTCCTGCAACCGGCAAAGTGGGGTCAAGGTTGA
GGCCCAGTGCAAAGTGGAGCTCCGGGGCAATGGTATCTATGACAACAGAGGCCACGGCATTATCACCAAGGGCGACAGCACCATCGTCAT
TGAAAACGATATCATTGGCAACCGGGGCAGCGGGCTGCAGCTGCTGCCCAGGTCCGACACTAAAGTAATAAAGAACCGGATCCACTCGTT
CCGGGCCTACGGCATCGCCGTGCGGGGCCGTGCCAAGGCCCTGGTGCAGGAAAACATCATCTTCCAGGGCAAAACCAGTAAGACCATCTT
TCAGCAGATCTCAAACAACCGAGAATGCATCATGCAAAACAACAAGTTCCTGGTCTTCAAGAAAAAGTCTGATACGTGGCGCCTGGTGAA
CCCACCAGCACGGCCCCACCTTGAAAATTCTCTCAGACGTCCCTCGGCAGCCCACAATGGGCAGAAGGTGACAGCCATGGCAACGAGGAT
CACAGCCCGGGTGGAAGGTGGTTACCACAGCAACCGCAGTGTCTTCTGCACCATCCTGTGAGGACACAGACCTGCTTCAGGGCCAAGCCT
GGATGGGTGCTCAGAGGAGCTAAGGTGGAAATACTGCCTGAAAAGACTCCGCCCCTCCCCCTCCCCCTCGAACAAATGGGTCCCGGGCCT
CCAAAACACGGTACCTCCAGAACACTTCAGCTCCACAGCCCATAGCAAGAAGAAAGTGGGCAATGTTTTTCAGGGAGAAGGGATAGAAGC
TGGTGGGTTTCCAGTCACTCGAAGTCTATAAAGATTGTGAAGAGCGGGGGAAGCTCAAATGCTGAAGCTTTTGGTCAGGATTTTCTCTGA
GTTCTAAGGAACTGTGTTTTACACACACCAAACCCAGACTCTTCTCAGGAAAGAGCAGATTTACTTCTGATGGCGGGAAGTGATTCTAGT
GAGGTGGAGAGAGACAACTGCTCCAGAATTTTCCCCTTTGCTAGAGCTGTCTCCCTCTCAATCCCTCCAGGGACCCCACCACACCCTCCC
AGCTGTCTCTGGAGGCTGGAGGAGTTGAGTTTGGTTGACTTGAGGACTTGGACATGGACCTGGGAGGAAGGAAGGACCTGGGAGCAACAG
GAGACCCCATGGAAAGGCTGCCCCAGGGATGACAAGAGGGACATGCTGAAACAGGTGGGGCTGCAGCGTGCAGGCAGATGCTAGGCTGGG
TGGGCAGGGATGCACAAGGCTCTACTCCATCCCCAGAGAGCTCCCAAATGCAGAAGGATTCAAACCCCATGTGAGCGTGCCCACACCAGC
CGCCCCTCCTGAGCATCAGCCTGTTCAGATGAGGGTACCTGGGCCTCTCGTTCGCATCTGTGTTCTCATGGATGAGCGCTGGTCTTTACT
GACCCTCCCAAGCCTCCCCACTCTGTGCCTTGGCTCATGCTCTTTCCTCCTCCCGGCATGCCCTTCTCCCCCATCTCCGTGTCCTCGTTC
CTCAAGGTTTAGCCGAGACACTGCCACCTCCACATAGCTCTCCCTGCCCTCTTTCCCCCTCTGGGCCTCAGTGGCCTTTCTCTGCTCCCT
CTCAGGGTACTGAGCACTTTCTGCCTTGTCCTGGAGCTATCTGGGTCCATTGCCTGACCCCCCACTCACCTGTGTGCTCCCCGTAGGTAG
GGCCACTTCTGACTGTGTGTCCCCAGATCCAGCCTGGGGTTGGGGTAGGATTAGTGGCCTGAGTGAGGAGAGGAAGGCCAGCTCCCAGAG
GACTTTACTGAACCGTACTGTGAATATGTCCAAGTCCCAAAGCCAGGTGAGGTCAGACCCCACTGCCTGAGGAAGAGGGCTGGATGCAGG
GCCAGCTCAACCTGAACAATCCCCTCCCACTCGGCCTTTCCTGTGGGGCCTTCACCAGCCTGCTGGGGTCACTGTCGTGCACTTGGCTGC
GTGGCTGGTTCTATTGGCCCTAGGTGCTGCTCTGTTGGGTGGGATGGGAGGGGGTAGAGGGAGCCAGGAGCACTGGGTTCTCCCTGAGAA
CACTGGGCACAAGAGTACTGGCCTCTTCTATCCCTGGCACTGTCCTTTGCACTTGTTTGGTGGCCCCAATGTGAGTCGCTGTAAAAAATG
CTGCCGTTACTATTTTCTAAGAAATGACTTTTCTGTGAACCAACAGTAACAAAAACCTCAGTAACCAAAATAAAGTTCTATATTTTAAAA

>30997_30997_3_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000380249_FBXO10_chr9_37529257_ENST00000432825_length(amino acids)=1352AA_BP=919
MFLFGHLCSSLQLTPFLIDHQGNFHPHRLAVENEAAHIHVREAKMSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTP
ALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHP
LITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWYLYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCC
DIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSLQLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALL
LLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILSSTALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVC
PVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPAPAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQVPNLIPVLMFK
LGRPLEPILYNDILYTLPKLGVHKVCIGQILRIIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIA
KAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPS
LTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFTAGEHTILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLT
PPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTVAGIPNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNR
LMASRGRSFKQTSLALVHECNQIHHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITEN
VIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSE
LPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANN
SISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQE
NIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCT

--------------------------------------------------------------
>30997_30997_4_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000380249_FBXO10_chr9_37529257_ENST00000541829_length(transcript)=4291nt_BP=2989nt
GTTCGAGCTTCCCGGCTGCTTTGTTTACCTAATCAAGCCTGGGCAATGGCGGGCGCCCCTCCCGCAGCCTCGCTGCCGCCTTGCAGGTTG
ATCTCAGACTGCTGTGCTAGCAATCAGTGAGACTCCGTGGGCGTAGGACTCTCCAAGCCAGTGAGATGAACTCGGTATCTCAGATGGAAA
TGCAGAAATCACCGTCTTCTCCATCGCTCACGCTGGGAGCTGTAGACCGGAGCTGTTCCTATTCGGCCATCTTTGCTCCTCCCTGCAACT
AACTCCATTCTTAATTGACCATCAAGGAAATTTCCATCCACACAGATTAGCAGTTGAAAATGAAGCTGCACACATACATGTAAGAGAAGC
AAAAATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCT
AAAGGAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAA
TGTAGTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACT
CAACTTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGG
TGGGGAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCC
AGTGTTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTG
GTATCTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTG
TGACAAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACA
GACAACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAG
TCTTCAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACT
TCTGAAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTT
AAATCTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACT
ATCTTCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACA
GCAGGAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTG
GAGGATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCC
TGCGCCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGC
CCAAGCAGATTCCTCCCAGGTGCCAAATCTGATTCCAGTTTTGATGTTCAAATTGGGAAGACCACTGGAACCTATATTATATAATGATAT
ATTGTATACTTTACCTAAGCTTGGTGTTCACAAGGTGTGTATAGGACAAATTCTACGAATAATACAACTACTTGGAACCACACCACGACT
AAGAGCTGTCACTTTGCGCTTGCTGACATCTTTGTGGGAAAAGCAGGACCGAGTCTATCCTGAACTGCAGCGTTTCATGGCTGTGTCTGA
TGTACCTTCTCTTTCGGTGGGCAAGGAAGTCCAATGGGAGAAACTGATTGCAAAAGCAGCATCAATCAGAGATATATGTAAGCAGAGGCC
ATATCAACATGGTGCAGATATGTTGGCAGCTATTTCTCAAGTGTTGAATGAATGCACCAAGCCTGATCAAGCTACTCCAGCAGCCTTGGT
ATTACAGGGTCTTCATGCACTCTGTCAAGCTGAGGTTGTTTGCATTCGCTCCACTTGGAATGCTCTCTCTCCAAAGCTGAGTTGTGACAC
AAGACCTCTCATTCTGAAGACACTGAGTGAACTATTTTCTCTAGTTCCTTCCTTAACGGTCAATACAACTGAATATGAGAATTTTAAAGT
TCAAGTCCTCAGCTTCCTCTGGACTCATACTCAAAACAAGGACCCAATTGTAGCAAATGCTGCATATAGATCCCTGGCCAACTTTACTGC
AGGAGAACACACCATTCTTCATCTGCCTGAAAAGATAAGACCAGAAATTCCCATTCCTGAAGAGTTAGATGACGATGAAGATGTTGAGGA
TGTGGATCTTTCAGTTCCTGGCTCTTGCTATCTCAAACTGTTGTCACTCACTCCCCCTTTGGTTTTACCAGCTTTGGAGGAATTTTTTAC
ATCACTTGTGAAGCAAGAAATGGTGAATATGCCTCGTGGGATATATCACTCTGCATTAAAAGGAGGTGCCCGCTCAGACCAAGGAAAGAC
TGTAGCAGGAATCCCCAATTTTATATTGAAAATGTATGAAACAAACAAGCAACCAGGACTGAAACCTGGCCTTGCAGGTGGTATGTTATT
TTGCTATGATGTTTCCATGTATCAGAGTAAAGATGGAAAACCATTGAACAGACTGATGGCCAGCAGAGGGCGAAGTTTCAAGCAGACTTC
ACTTGCTCTTGTACATGAGTGTAACCAGATCCACCATGGCCTTCGCTCTGGCATTGTCGTCCTTGGCAATGGGAAAGGCATCATCCGGAA
CAATCAAATCTTTTCCAATAAGGAGGCTGGCATTTACATCCTGTACCACGGAAACCCCGTTGTGAGCGGGAACCACATCTTCAAGGGCCG
TGCTGCCGGCATAGCAGTGAATGAGAACGGCAAAGGCCTCATCACAGAAAATGTCATCCGTGAGAATCAGTGGGGAGGTGTGGACATCCG
CCGTGGAGGGATCCCCGTTCTCAGGAGTAACCTCATCTGCTTTGGCTATTCAGATGGTGTGGTTGTGGGAGACGAAGGCAAAGGCCTCAT
AGAAGGAAATACCATCTACGCTAACAAGGGCTGTGGTGTGTGGATGATGTCGTCCAGCCTCCCCCATGTCACCAGCAACCACGTCAGCTA
CAATGGCCTGTATGGAGTGGCAGTATTTAGCCAGAAGGATGGCTCCAGCGAGTTACCTCGAGGCCACAGGGCTCAAGAGAACTTCAGCGA
GGATGGGGACGCCATCCTCTGGGAGACAGAGCTGGAGAAGGAGGACGACCCACTGCGCCGGCCCATCACCATAGCTCTTGTTGAGTCTAA
CAGTATTAATCACAATGGAGCCTCAGGACTCTATGTCCAGAGCAGCGAGGCACTGCATGTCATCACCAATGTGATCCACGCGAATGGGGA
CAGAGGCATTACTGTGGCCCAGAGCAGCCAACCCACCCGAGTGGCCAACAACAGCATCTCCTGCAACCGGCAAAGTGGGGTCAAGGTTGA
GGCCCAGTGCAAAGTGGAGCTCCGGGGCAATGGTATCTATGACAACAGAGGCCACGGCATTATCACCAAGGGCGACAGCACCATCGTCAT
TGAAAACGATATCATTGGCAACCGGGGCAGCGGGCTGCAGCTGCTGCCCAGGTCCGACACTAAAGTAATAAAGAACCGGATCCACTCGTT
CCGGGCCTACGGCATCGCCGTGCGGGGCCGTGCCAAGGCCCTGGTGCAGGAAAACATCATCTTCCAGGGCAAAACCAGTAAGACCATCTT
TCAGCAGATCTCAAACAACCGAGAATGCATCATGCAAAACAACAAGTTCCTGGTCTTCAAGAAAAAGTCTGATACGTGGCGCCTGGTGAA
CCCACCAGCACGGCCCCACCTTGAAAATTCTCTCAGACGTCCCTCGGCAGCCCACAATGGGCAGAAGGTGACAGCCATGGCAACGAGGAT

>30997_30997_4_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000380249_FBXO10_chr9_37529257_ENST00000541829_length(amino acids)=1353AA_BP=919
MFLFGHLCSSLQLTPFLIDHQGNFHPHRLAVENEAAHIHVREAKMSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTP
ALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHP
LITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWYLYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCC
DIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSLQLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALL
LLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILSSTALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVC
PVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPAPAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQVPNLIPVLMFK
LGRPLEPILYNDILYTLPKLGVHKVCIGQILRIIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIA
KAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPS
LTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFTAGEHTILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLT
PPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTVAGIPNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNR
LMASRGRSFKQTSLALVHECNQIHHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITEN
VIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSE
LPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANN
SISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQE
NIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCT

--------------------------------------------------------------
>30997_30997_5_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000605086_FBXO10_chr9_37529257_ENST00000432825_length(transcript)=4052nt_BP=1095nt
TGCAACTAGAGTTTCTTCAATATTTTCTAGGTGTGTATAGGACAAATTCTACGAATAATACAACTACTTGGAACCACACCACGACTAAGA
GCTGTCACTTTGCGCTTGCTGACATCTTTGTGGGAAAAGCAGGACCGAGTCTATCCTGAACTGCAGCGTTTCATGGCTGTGTCTGATGTA
CCTTCTCTTTCGGTGGGCAAGGAAGTCCAATGGGAGAAACTGATTGCAAAAGCAGCATCAATCAGAGATATATGTAAGCAGAGGCCATAT
CAACATGGTGCAGATATGTTGGCAGCTATTTCTCAAGTGTTGAATGAATGCACCAAGCCTGATCAAGCTACTCCAGCAGCCTTGGTATTA
CAGGGTCTTCATGCACTCTGTCAAGCTGAGGTTGTTTGCATTCGCTCCACTTGGAATGCTCTCTCTCCAAAGCTGAGTTGTGACACAAGA
CCTCTCATTCTGAAGACACTGAGTGAACTATTTTCTCTAGTTCCTTCCTTAACGGTCAATACAACTGAATATGAGAATTTTAAAGTTCAA
GTCCTCAGCTTCCTCTGGACTCATACTCAAAACAAGGACCCAATTGTAGCAAATGCTGCATATAGATCCCTGGCCAACTTTACTGCAGGA
GAACACACCATTCTTCATCTGCCTGAAAAGATAAGACCAGAAATTCCCATTCCTGAAGAGTTAGATGACGATGAAGATGTTGAGGATGTG
GATCTTTCAGTTCCTGGCTCTTGCTATCTCAAACTGTTGTCACTCACTCCCCCTTTGGTTTTACCAGCTTTGGAGGAATTTTTTACATCA
CTTGTGAAGCAAGAAATGGTGAATATGCCTCGTGGGATATATCACTCTGCATTAAAAGGAGGTGCCCGCTCAGACCAAGGAAAGACTGTA
GCAGGAATCCCCAATTTTATATTGAAAATGTATGAAACAAACAAGCAACCAGGACTGAAACCTGGCCTTGCAGGTGGTATGTTATTTTGC
TATGATGTTTCCATGTATCAGAGTAAAGATGGAAAACCATTGAACAGACTGATGGCCAGCAGAGGGCGAAGTTTCAAGCAGACTTCACTT
GCTCTTGTACATGAGTGTAACCAGATCCACCATGGCCTTCGCTCTGGCATTGTCGTCCTTGGCAATGGGAAAGGCATCATCCGGAACAAT
CAAATCTTTTCCAATAAGGAGGCTGGCATTTACATCCTGTACCACGGAAACCCCGTTGTGAGCGGGAACCACATCTTCAAGGGCCGTGCT
GCCGGCATAGCAGTGAATGAGAACGGCAAAGGCCTCATCACAGAAAATGTCATCCGTGAGAATCAGTGGGGAGGTGTGGACATCCGCCGT
GGAGGGATCCCCGTTCTCAGGAGTAACCTCATCTGCTTTGGCTATTCAGATGGTGTGGTTGTGGGAGACGAAGGCAAAGGCCTCATAGAA
GGAAATACCATCTACGCTAACAAGGGCTGTGGTGTGTGGATGATGTCGTCCAGCCTCCCCCATGTCACCAGCAACCACGTCAGCTACAAT
GGCCTGTATGGAGTGGCAGTATTTAGCCAGAAGGATGGCTCCAGCGAGTTACCTCGAGGCCACAGGGCTCAAGAGAACTTCAGCGAGGAT
GGGGACGCCATCCTCTGGGAGACAGAGCTGGAGAAGGAGGACGACCCACTGCGCCGGCCCATCACCATAGCTCTTGTTGAGTCTAACAGT
ATTAATCACAATGGAGCCTCAGGACTCTATGTCCAGAGCAGCGAGGCACTGCATGTCATCACCAATGTGATCCACGCGAATGGGGACAGA
GGCATTACTGTGGCCCAGAGCAGCCAACCCACCCGAGTGGCCAACAACAGCATCTCCTGCAACCGGCAAAGTGGGGTCAAGGTTGAGGCC
CAGTGCAAAGTGGAGCTCCGGGGCAATGGTATCTATGACAACAGAGGCCACGGCATTATCACCAAGGGCGACAGCACCATCGTCATTGAA
AACGATATCATTGGCAACCGGGGCAGCGGGCTGCAGCTGCTGCCCAGGTCCGACACTAAAGTAATAAAGAACCGGATCCACTCGTTCCGG
GCCTACGGCATCGCCGTGCGGGGCCGTGCCAAGGCCCTGGTGCAGGAAAACATCATCTTCCAGGGCAAAACCAGTAAGACCATCTTTCAG
CAGATCTCAAACAACCGAGAATGCATCATGCAAAACAACAAGTTCCTGGTCTTCAAGAAAAAGTCTGATACGTGGCGCCTGGTGAACCCA
CCAGCACGGCCCCACCTTGAAAATTCTCTCAGACGTCCCTCGGCAGCCCACAATGGGCAGAAGGTGACAGCCATGGCAACGAGGATCACA
GCCCGGGTGGAAGGTGGTTACCACAGCAACCGCAGTGTCTTCTGCACCATCCTGTGAGGACACAGACCTGCTTCAGGGCCAAGCCTGGAT
GGGTGCTCAGAGGAGCTAAGGTGGAAATACTGCCTGAAAAGACTCCGCCCCTCCCCCTCCCCCTCGAACAAATGGGTCCCGGGCCTCCAA
AACACGGTACCTCCAGAACACTTCAGCTCCACAGCCCATAGCAAGAAGAAAGTGGGCAATGTTTTTCAGGGAGAAGGGATAGAAGCTGGT
GGGTTTCCAGTCACTCGAAGTCTATAAAGATTGTGAAGAGCGGGGGAAGCTCAAATGCTGAAGCTTTTGGTCAGGATTTTCTCTGAGTTC
TAAGGAACTGTGTTTTACACACACCAAACCCAGACTCTTCTCAGGAAAGAGCAGATTTACTTCTGATGGCGGGAAGTGATTCTAGTGAGG
TGGAGAGAGACAACTGCTCCAGAATTTTCCCCTTTGCTAGAGCTGTCTCCCTCTCAATCCCTCCAGGGACCCCACCACACCCTCCCAGCT
GTCTCTGGAGGCTGGAGGAGTTGAGTTTGGTTGACTTGAGGACTTGGACATGGACCTGGGAGGAAGGAAGGACCTGGGAGCAACAGGAGA
CCCCATGGAAAGGCTGCCCCAGGGATGACAAGAGGGACATGCTGAAACAGGTGGGGCTGCAGCGTGCAGGCAGATGCTAGGCTGGGTGGG
CAGGGATGCACAAGGCTCTACTCCATCCCCAGAGAGCTCCCAAATGCAGAAGGATTCAAACCCCATGTGAGCGTGCCCACACCAGCCGCC
CCTCCTGAGCATCAGCCTGTTCAGATGAGGGTACCTGGGCCTCTCGTTCGCATCTGTGTTCTCATGGATGAGCGCTGGTCTTTACTGACC
CTCCCAAGCCTCCCCACTCTGTGCCTTGGCTCATGCTCTTTCCTCCTCCCGGCATGCCCTTCTCCCCCATCTCCGTGTCCTCGTTCCTCA
AGGTTTAGCCGAGACACTGCCACCTCCACATAGCTCTCCCTGCCCTCTTTCCCCCTCTGGGCCTCAGTGGCCTTTCTCTGCTCCCTCTCA
GGGTACTGAGCACTTTCTGCCTTGTCCTGGAGCTATCTGGGTCCATTGCCTGACCCCCCACTCACCTGTGTGCTCCCCGTAGGTAGGGCC
ACTTCTGACTGTGTGTCCCCAGATCCAGCCTGGGGTTGGGGTAGGATTAGTGGCCTGAGTGAGGAGAGGAAGGCCAGCTCCCAGAGGACT
TTACTGAACCGTACTGTGAATATGTCCAAGTCCCAAAGCCAGGTGAGGTCAGACCCCACTGCCTGAGGAAGAGGGCTGGATGCAGGGCCA
GCTCAACCTGAACAATCCCCTCCCACTCGGCCTTTCCTGTGGGGCCTTCACCAGCCTGCTGGGGTCACTGTCGTGCACTTGGCTGCGTGG
CTGGTTCTATTGGCCCTAGGTGCTGCTCTGTTGGGTGGGATGGGAGGGGGTAGAGGGAGCCAGGAGCACTGGGTTCTCCCTGAGAACACT
GGGCACAAGAGTACTGGCCTCTTCTATCCCTGGCACTGTCCTTTGCACTTGTTTGGTGGCCCCAATGTGAGTCGCTGTAAAAAATGCTGC
CGTTACTATTTTCTAAGAAATGACTTTTCTGTGAACCAACAGTAACAAAAACCTCAGTAACCAAAATAAAGTTCTATATTTTAAAAAAGG

>30997_30997_5_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000605086_FBXO10_chr9_37529257_ENST00000432825_length(amino acids)=765AA_BP=332
MRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGL
HALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFTAGEHT
ILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLTPPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTVAGI
PNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNRLMASRGRSFKQTSLALVHECNQIHHGLRSGIVVLGNGKGIIRNNQIF
SNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNT
IYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSINH
NGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDI
IGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNPPAR

--------------------------------------------------------------
>30997_30997_6_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000605086_FBXO10_chr9_37529257_ENST00000541829_length(transcript)=2397nt_BP=1095nt
TGCAACTAGAGTTTCTTCAATATTTTCTAGGTGTGTATAGGACAAATTCTACGAATAATACAACTACTTGGAACCACACCACGACTAAGA
GCTGTCACTTTGCGCTTGCTGACATCTTTGTGGGAAAAGCAGGACCGAGTCTATCCTGAACTGCAGCGTTTCATGGCTGTGTCTGATGTA
CCTTCTCTTTCGGTGGGCAAGGAAGTCCAATGGGAGAAACTGATTGCAAAAGCAGCATCAATCAGAGATATATGTAAGCAGAGGCCATAT
CAACATGGTGCAGATATGTTGGCAGCTATTTCTCAAGTGTTGAATGAATGCACCAAGCCTGATCAAGCTACTCCAGCAGCCTTGGTATTA
CAGGGTCTTCATGCACTCTGTCAAGCTGAGGTTGTTTGCATTCGCTCCACTTGGAATGCTCTCTCTCCAAAGCTGAGTTGTGACACAAGA
CCTCTCATTCTGAAGACACTGAGTGAACTATTTTCTCTAGTTCCTTCCTTAACGGTCAATACAACTGAATATGAGAATTTTAAAGTTCAA
GTCCTCAGCTTCCTCTGGACTCATACTCAAAACAAGGACCCAATTGTAGCAAATGCTGCATATAGATCCCTGGCCAACTTTACTGCAGGA
GAACACACCATTCTTCATCTGCCTGAAAAGATAAGACCAGAAATTCCCATTCCTGAAGAGTTAGATGACGATGAAGATGTTGAGGATGTG
GATCTTTCAGTTCCTGGCTCTTGCTATCTCAAACTGTTGTCACTCACTCCCCCTTTGGTTTTACCAGCTTTGGAGGAATTTTTTACATCA
CTTGTGAAGCAAGAAATGGTGAATATGCCTCGTGGGATATATCACTCTGCATTAAAAGGAGGTGCCCGCTCAGACCAAGGAAAGACTGTA
GCAGGAATCCCCAATTTTATATTGAAAATGTATGAAACAAACAAGCAACCAGGACTGAAACCTGGCCTTGCAGGTGGTATGTTATTTTGC
TATGATGTTTCCATGTATCAGAGTAAAGATGGAAAACCATTGAACAGACTGATGGCCAGCAGAGGGCGAAGTTTCAAGCAGACTTCACTT
GCTCTTGTACATGAGTGTAACCAGATCCACCATGGCCTTCGCTCTGGCATTGTCGTCCTTGGCAATGGGAAAGGCATCATCCGGAACAAT
CAAATCTTTTCCAATAAGGAGGCTGGCATTTACATCCTGTACCACGGAAACCCCGTTGTGAGCGGGAACCACATCTTCAAGGGCCGTGCT
GCCGGCATAGCAGTGAATGAGAACGGCAAAGGCCTCATCACAGAAAATGTCATCCGTGAGAATCAGTGGGGAGGTGTGGACATCCGCCGT
GGAGGGATCCCCGTTCTCAGGAGTAACCTCATCTGCTTTGGCTATTCAGATGGTGTGGTTGTGGGAGACGAAGGCAAAGGCCTCATAGAA
GGAAATACCATCTACGCTAACAAGGGCTGTGGTGTGTGGATGATGTCGTCCAGCCTCCCCCATGTCACCAGCAACCACGTCAGCTACAAT
GGCCTGTATGGAGTGGCAGTATTTAGCCAGAAGGATGGCTCCAGCGAGTTACCTCGAGGCCACAGGGCTCAAGAGAACTTCAGCGAGGAT
GGGGACGCCATCCTCTGGGAGACAGAGCTGGAGAAGGAGGACGACCCACTGCGCCGGCCCATCACCATAGCTCTTGTTGAGTCTAACAGT
ATTAATCACAATGGAGCCTCAGGACTCTATGTCCAGAGCAGCGAGGCACTGCATGTCATCACCAATGTGATCCACGCGAATGGGGACAGA
GGCATTACTGTGGCCCAGAGCAGCCAACCCACCCGAGTGGCCAACAACAGCATCTCCTGCAACCGGCAAAGTGGGGTCAAGGTTGAGGCC
CAGTGCAAAGTGGAGCTCCGGGGCAATGGTATCTATGACAACAGAGGCCACGGCATTATCACCAAGGGCGACAGCACCATCGTCATTGAA
AACGATATCATTGGCAACCGGGGCAGCGGGCTGCAGCTGCTGCCCAGGTCCGACACTAAAGTAATAAAGAACCGGATCCACTCGTTCCGG
GCCTACGGCATCGCCGTGCGGGGCCGTGCCAAGGCCCTGGTGCAGGAAAACATCATCTTCCAGGGCAAAACCAGTAAGACCATCTTTCAG
CAGATCTCAAACAACCGAGAATGCATCATGCAAAACAACAAGTTCCTGGTCTTCAAGAAAAAGTCTGATACGTGGCGCCTGGTGAACCCA
CCAGCACGGCCCCACCTTGAAAATTCTCTCAGACGTCCCTCGGCAGCCCACAATGGGCAGAAGGTGACAGCCATGGCAACGAGGATCACA

>30997_30997_6_FOCAD-FBXO10_FOCAD_chr9_20885229_ENST00000605086_FBXO10_chr9_37529257_ENST00000541829_length(amino acids)=765AA_BP=332
MRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGL
HALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFTAGEHT
ILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLTPPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTVAGI
PNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNRLMASRGRSFKQTSLALVHECNQIHHGLRSGIVVLGNGKGIIRNNQIF
SNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNT
IYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSINH
NGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDI
IGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNPPAR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for FOCAD-FBXO10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for FOCAD-FBXO10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for FOCAD-FBXO10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource