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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FOCAD-PDZRN4 (FusionGDB2 ID:31004)

Fusion Gene Summary for FOCAD-PDZRN4

check button Fusion gene summary
Fusion gene informationFusion gene name: FOCAD-PDZRN4
Fusion gene ID: 31004
HgeneTgene
Gene symbol

FOCAD

PDZRN4

Gene ID

54914

29951

Gene namefocadhesinPDZ domain containing ring finger 4
SynonymsKIAA1797LNX4|SAMCAP3L
Cytomap

9p21.3

12q12

Type of geneprotein-codingprotein-coding
DescriptionfocadhesinPDZ domain-containing RING finger protein 4IMAGE5767589SEMACAP3-like proteinligand of Numb protein X 4
Modification date2020031320200313
UniProtAcc

Q5VW36

.
Ensembl transtripts involved in fusion geneENST00000338382, ENST00000380249, 
ENST00000604828, ENST00000605086, 
ENST00000298919, ENST00000402685, 
ENST00000539469, 
Fusion gene scores* DoF score16 X 12 X 11=211213 X 9 X 7=819
# samples 1714
** MAII scorelog2(17/2112*10)=-3.63500318322075
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/819*10)=-2.54843662469604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FOCAD [Title/Abstract] AND PDZRN4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFOCAD(20789607)-PDZRN4(41946458), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across FOCAD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PDZRN4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-J9-A8CP-01AFOCADchr9

20789607

+PDZRN4chr12

41946458

+
ChimerDB4PRADTCGA-J9-A8CPFOCADchr9

20789607

+PDZRN4chr12

41946458

+


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Fusion Gene ORF analysis for FOCAD-PDZRN4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000338382ENST00000298919FOCADchr9

20789607

+PDZRN4chr12

41946458

+
In-frameENST00000338382ENST00000402685FOCADchr9

20789607

+PDZRN4chr12

41946458

+
In-frameENST00000338382ENST00000539469FOCADchr9

20789607

+PDZRN4chr12

41946458

+
In-frameENST00000380249ENST00000298919FOCADchr9

20789607

+PDZRN4chr12

41946458

+
In-frameENST00000380249ENST00000402685FOCADchr9

20789607

+PDZRN4chr12

41946458

+
In-frameENST00000380249ENST00000539469FOCADchr9

20789607

+PDZRN4chr12

41946458

+
intron-3CDSENST00000604828ENST00000298919FOCADchr9

20789607

+PDZRN4chr12

41946458

+
intron-3CDSENST00000604828ENST00000402685FOCADchr9

20789607

+PDZRN4chr12

41946458

+
intron-3CDSENST00000604828ENST00000539469FOCADchr9

20789607

+PDZRN4chr12

41946458

+
intron-3CDSENST00000605086ENST00000298919FOCADchr9

20789607

+PDZRN4chr12

41946458

+
intron-3CDSENST00000605086ENST00000402685FOCADchr9

20789607

+PDZRN4chr12

41946458

+
intron-3CDSENST00000605086ENST00000539469FOCADchr9

20789607

+PDZRN4chr12

41946458

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000380249FOCADchr920789607+ENST00000402685PDZRN4chr1241946458+3955181923237261164
ENST00000380249FOCADchr920789607+ENST00000539469PDZRN4chr1241946458+4169181923237261164
ENST00000380249FOCADchr920789607+ENST00000298919PDZRN4chr1241946458+4419181923237261164
ENST00000338382FOCADchr920789607+ENST00000402685PDZRN4chr1241946458+35911455033621120
ENST00000338382FOCADchr920789607+ENST00000539469PDZRN4chr1241946458+38051455033621120
ENST00000338382FOCADchr920789607+ENST00000298919PDZRN4chr1241946458+40551455033621120

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000380249ENST00000402685FOCADchr920789607+PDZRN4chr1241946458+0.0046094450.99539053
ENST00000380249ENST00000539469FOCADchr920789607+PDZRN4chr1241946458+0.002933350.9970667
ENST00000380249ENST00000298919FOCADchr920789607+PDZRN4chr1241946458+0.0018860670.998114
ENST00000338382ENST00000402685FOCADchr920789607+PDZRN4chr1241946458+0.003008180.99699175
ENST00000338382ENST00000539469FOCADchr920789607+PDZRN4chr1241946458+0.0018670590.998133
ENST00000338382ENST00000298919FOCADchr920789607+PDZRN4chr1241946458+0.001128220.99887174

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Fusion Genomic Features for FOCAD-PDZRN4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FOCADchr920789607+PDZRN4chr1241946457+2.44E-101
FOCADchr920789607+PDZRN4chr1241946457+2.44E-101
FOCADchr920789607+PDZRN4chr1241946457+2.44E-101
FOCADchr920789607+PDZRN4chr1241946457+2.44E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FOCAD-PDZRN4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:20789607/chr12:41946458)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FOCAD

Q5VW36

.
FUNCTION: Potential tumor suppressor in gliomas. {ECO:0000250, ECO:0000269|PubMed:22427331}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOCADchr9:20789607chr12:41946458ENST00000338382+1043404_4244851802.0TransmembraneHelical
HgeneFOCADchr9:20789607chr12:41946458ENST00000338382+1043441_4614851802.0TransmembraneHelical
HgeneFOCADchr9:20789607chr12:41946458ENST00000380249+1346404_4244851802.0TransmembraneHelical
HgeneFOCADchr9:20789607chr12:41946458ENST00000380249+1346441_4614851802.0TransmembraneHelical
TgenePDZRN4chr9:20789607chr12:41946458ENST00000298919410655_689141777.0Coiled coilOntology_term=ECO:0000255
TgenePDZRN4chr9:20789607chr12:41946458ENST00000402685410655_6894011037.0Coiled coilOntology_term=ECO:0000255
TgenePDZRN4chr9:20789607chr12:41946458ENST0000053946928655_689143779.0Coiled coilOntology_term=ECO:0000255
TgenePDZRN4chr9:20789607chr12:41946458ENST00000298919410533_536141777.0Compositional biasNote=Poly-Glu
TgenePDZRN4chr9:20789607chr12:41946458ENST00000298919410957_960141777.0Compositional biasNote=Poly-Arg
TgenePDZRN4chr9:20789607chr12:41946458ENST00000402685410533_5364011037.0Compositional biasNote=Poly-Glu
TgenePDZRN4chr9:20789607chr12:41946458ENST00000402685410957_9604011037.0Compositional biasNote=Poly-Arg
TgenePDZRN4chr9:20789607chr12:41946458ENST0000053946928533_536143779.0Compositional biasNote=Poly-Glu
TgenePDZRN4chr9:20789607chr12:41946458ENST0000053946928957_960143779.0Compositional biasNote=Poly-Arg
TgenePDZRN4chr9:20789607chr12:41946458ENST00000298919410224_314141777.0DomainPDZ 1
TgenePDZRN4chr9:20789607chr12:41946458ENST00000298919410402_486141777.0DomainPDZ 2
TgenePDZRN4chr9:20789607chr12:41946458ENST00000402685410402_4864011037.0DomainPDZ 2
TgenePDZRN4chr9:20789607chr12:41946458ENST0000053946928224_314143779.0DomainPDZ 1
TgenePDZRN4chr9:20789607chr12:41946458ENST0000053946928402_486143779.0DomainPDZ 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOCADchr9:20789607chr12:41946458ENST00000338382+10431036_10564851802.0TransmembraneHelical
HgeneFOCADchr9:20789607chr12:41946458ENST00000380249+13461036_10564851802.0TransmembraneHelical
TgenePDZRN4chr9:20789607chr12:41946458ENST00000298919410116_161141777.0Compositional biasNote=Gly-rich
TgenePDZRN4chr9:20789607chr12:41946458ENST00000402685410116_1614011037.0Compositional biasNote=Gly-rich
TgenePDZRN4chr9:20789607chr12:41946458ENST0000053946928116_161143779.0Compositional biasNote=Gly-rich
TgenePDZRN4chr9:20789607chr12:41946458ENST00000402685410224_3144011037.0DomainPDZ 1
TgenePDZRN4chr9:20789607chr12:41946458ENST0000029891941018_56141777.0Zinc fingerRING-type%3B degenerate
TgenePDZRN4chr9:20789607chr12:41946458ENST0000040268541018_564011037.0Zinc fingerRING-type%3B degenerate
TgenePDZRN4chr9:20789607chr12:41946458ENST000005394692818_56143779.0Zinc fingerRING-type%3B degenerate


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Fusion Gene Sequence for FOCAD-PDZRN4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>31004_31004_1_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000338382_PDZRN4_chr12_41946458_ENST00000298919_length(transcript)=4055nt_BP=1455nt
ATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCTAAAG
GAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAATGTA
GTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACTCAAC
TTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGGTGGG
GAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCCAGTG
TTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTGGTAT
CTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTGTGAC
AAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACAGACA
ACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAGTCTT
CAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACTTCTG
AAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTTAAAT
CTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACTATCT
TCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACAGCAG
GAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTGGAGG
ATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCCTGCG
CCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGCCCAA
GCAGATTCCTCCCAGGAGGTCGAGTTGTGTCGTGTTAGCAGTCAAGAGAAGCTGGGCCTGACAGTCTGTTACCGAACAGATGATGAAGAA
GACACCGGCATTTATGTCAGCGAGGTTGACCCAAATAGCATTGCTGCCAAAGACGGCCGGATTCGAGAAGGGGATCGGATTTTGCAAATA
AATGGGGAAGATGTCCAGAATCGAGAAGAAGCAGTGGCCTTGCTGTCTAACGATGAGTGTAAGAGAATCGTGCTGCTTGTTGCAAGGCCA
GAGATTCAGCTGGATGAAGGCTGGCTGGAAGATGAAAGGAATGAATTCTTAGAGGAGTTAAACTTGGAGATGTTGGAAGAAGAGCATAAT
GAAGCAATGCAGCCCACTGCCAATGAGGTGGAGCAGCCAAAAAAGCAAGAAGAAGAAGAAGGCACAACAGACACTGCAACATCCTCATCC
AACAACCATGAGAAGGACAGTGGAGTAGGACGTACAGATGAAAGCTTGCGAAATGATGAGAGCTCAGAGCAGGAGAATGCAGCCGAGGAC
CCCAATAGCACATCTTTGAAGAGCAAGAGAGACCTGGGGCAGAGCCAAGACACTCTGGGAAGTGTTGAACTTCAGTACAATGAGAGCCTC
GTATCTGGTGAATACATTGACTCAGACTGCATTGGCAACCCAGATGAGGACTGTGAAAGATTCAGGCAGCTCTTGGAGCTCAAATGCAAG
ATTCGAAATCATGGAGAGTATGACCTGTATTACTCAAGCAGCACAATTGAATGCAATCAAGGGGAGCAAGAGGGAGTGGAGCATGAGCTA
CAGTTGCTTAATGAAGAACTGAGAAACATTGAGCTTGAGTGTCAGAATATCATGCAGGCTCACAGGCTCCAGAAAGTGACAGACCAGTAT
GGAGACATCTGGACATTGCATGATGGAGGATTCCGGAATTATAACACCAGCATAGATATGCAAAGGGGAAAGCTAGATGACATCATGGAG
CATCCAGAAAAGTCTGACAAGGACAGTTCTAGTGCTTACAACACAGCTGAGAGCTGCAGAAGTACTCCGCTCACTGTAGACCGTTCCCCT
GACAGTTCCCTTCCAAGGGTGATCAACCTCACCAATAAGAAAAACCTGAGAAGCACAATGGCAGCCACCCAGTCCTCTTCCGGACAGAGC
AGTAAAGAGTCGACCTCCACCAAAGCCAAAACCACTGAGCAAGGTTGTAGCGCTGAAAGCAAGGAGAAGGTTTTAGAAGGCAGCAAGCTT
CCTGATCAAGAGAAGGCAGTCAGCGAACACATCCCTTACCTCTCTCCTTACCACAGCTCCTCATATAGATATGCAAACATCCCAGCACAC
GCCCGGCATTATCAAAGCTACATGCAGTTAATTCAACAGAAATCTGCAGTCGAGTATGCTCAGAGTCAGCTCAGCTTGGTGAGCATGTGC
AAGGAGTCTCAGAAGTGTTCAGAGCCCAAGATGGAATGGAAGGTGAAAATTAGGAGCGACGGGACACGGTACATCACAAAGAGACCCGTG
CGAGACCGAATCCTGAAGGAACGTGCCTTAAAGATCAAGGAAGAGCGGAGTGGCATGACCACAGACGATGACACCATGAGCGAGATGAAA
ATGGGGCGCTACTGGAGCAAAGAGGAGAGAAAGCAGCACCTGGTTAGGGCCAAAGAGCAGCGCCGTCGCCGTGAGTTCATGATGCGAAGC
AGGTTAGAGTGTCTCAAGGAGAGCCCTCAGAGCGGCAGTGAGGGCAAGAAGGAGATCAATATCATTGAACTGAGTCACAAAAAGATGATG
AAAAAGAGAAACAAGAAAATTTTGGACAACTGGATGACAATCCAAGAACTGATGACCCATGGGGCCAAGTCTCCAGATGGCACGAGAGTC
CATAATGCCTTCTTGTCGGTGACCACTGTATGACCGAATGAATGGAATGCATGCGACTGATTTTAGGAGGATGCTACCAGTTTCGGTAGA
GTATGATTGCCTCGTTCAATGTGGCGTTTTTATATATATTTTGTGACTCTTTATAGTTTAAATTTTTTGTAAGCAAAAAATACCTGGTAA
TTTTTCATTTGTTTTTCATATACTGGTACCTTCTTTTTGGCTGAGATCTTTCTTTTACTTGTGATATATTCATATTACTCGTTTATAAAA
AATCAAAAACAAAAGGAAAGAAAACAAAAAAAACTTGCACAAAAATACTGAGGAGCCAATTAATTTCCTACTTCAATGTATCTAATGTAA
GTGAAAATCTGGATTTATTTCTCTAGTTTACTTATTTTCTACTTTAATAATAACTCAATGCCAAAATATTTCTATGCTTGTTTCTTGGCA
TAATACATTTTAAATCAAACCTGTTCGTAATAAATCATGTGCCACATCTTGTCTTACACATAAAAGCCACTGCTTTTAACATCCCATTGT
ACATTTAACACATAAATGGTGTTAACATCCCATTGTACATTTAACACATAAATGGCCATTGTCTTTGTCTCAGTAAAGTGTAGGTGGACA
ATCTTCCTGTGATATGTAGTGACATTGGTCATGTAGCTAGATAATTATGGTAATTGTGACAATTAAAGAGAAATAAATTATTGATTATCC

>31004_31004_1_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000338382_PDZRN4_chr12_41946458_ENST00000298919_length(amino acids)=1120AA_BP=484
MSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILN
LIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHPLITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWY
LYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCCDIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSL
QLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALLLLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILS
STALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVCPVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPA
PAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQI
NGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSS
NNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQDTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCK
IRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQNIMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIME
HPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNLRSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKL
PDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPV
RDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLECLKESPQSGSEGKKEINIIELSHKKMM

--------------------------------------------------------------
>31004_31004_2_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000338382_PDZRN4_chr12_41946458_ENST00000402685_length(transcript)=3591nt_BP=1455nt
ATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCTAAAG
GAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAATGTA
GTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACTCAAC
TTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGGTGGG
GAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCCAGTG
TTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTGGTAT
CTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTGTGAC
AAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACAGACA
ACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAGTCTT
CAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACTTCTG
AAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTTAAAT
CTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACTATCT
TCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACAGCAG
GAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTGGAGG
ATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCCTGCG
CCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGCCCAA
GCAGATTCCTCCCAGGAGGTCGAGTTGTGTCGTGTTAGCAGTCAAGAGAAGCTGGGCCTGACAGTCTGTTACCGAACAGATGATGAAGAA
GACACCGGCATTTATGTCAGCGAGGTTGACCCAAATAGCATTGCTGCCAAAGACGGCCGGATTCGAGAAGGGGATCGGATTTTGCAAATA
AATGGGGAAGATGTCCAGAATCGAGAAGAAGCAGTGGCCTTGCTGTCTAACGATGAGTGTAAGAGAATCGTGCTGCTTGTTGCAAGGCCA
GAGATTCAGCTGGATGAAGGCTGGCTGGAAGATGAAAGGAATGAATTCTTAGAGGAGTTAAACTTGGAGATGTTGGAAGAAGAGCATAAT
GAAGCAATGCAGCCCACTGCCAATGAGGTGGAGCAGCCAAAAAAGCAAGAAGAAGAAGAAGGCACAACAGACACTGCAACATCCTCATCC
AACAACCATGAGAAGGACAGTGGAGTAGGACGTACAGATGAAAGCTTGCGAAATGATGAGAGCTCAGAGCAGGAGAATGCAGCCGAGGAC
CCCAATAGCACATCTTTGAAGAGCAAGAGAGACCTGGGGCAGAGCCAAGACACTCTGGGAAGTGTTGAACTTCAGTACAATGAGAGCCTC
GTATCTGGTGAATACATTGACTCAGACTGCATTGGCAACCCAGATGAGGACTGTGAAAGATTCAGGCAGCTCTTGGAGCTCAAATGCAAG
ATTCGAAATCATGGAGAGTATGACCTGTATTACTCAAGCAGCACAATTGAATGCAATCAAGGGGAGCAAGAGGGAGTGGAGCATGAGCTA
CAGTTGCTTAATGAAGAACTGAGAAACATTGAGCTTGAGTGTCAGAATATCATGCAGGCTCACAGGCTCCAGAAAGTGACAGACCAGTAT
GGAGACATCTGGACATTGCATGATGGAGGATTCCGGAATTATAACACCAGCATAGATATGCAAAGGGGAAAGCTAGATGACATCATGGAG
CATCCAGAAAAGTCTGACAAGGACAGTTCTAGTGCTTACAACACAGCTGAGAGCTGCAGAAGTACTCCGCTCACTGTAGACCGTTCCCCT
GACAGTTCCCTTCCAAGGGTGATCAACCTCACCAATAAGAAAAACCTGAGAAGCACAATGGCAGCCACCCAGTCCTCTTCCGGACAGAGC
AGTAAAGAGTCGACCTCCACCAAAGCCAAAACCACTGAGCAAGGTTGTAGCGCTGAAAGCAAGGAGAAGGTTTTAGAAGGCAGCAAGCTT
CCTGATCAAGAGAAGGCAGTCAGCGAACACATCCCTTACCTCTCTCCTTACCACAGCTCCTCATATAGATATGCAAACATCCCAGCACAC
GCCCGGCATTATCAAAGCTACATGCAGTTAATTCAACAGAAATCTGCAGTCGAGTATGCTCAGAGTCAGCTCAGCTTGGTGAGCATGTGC
AAGGAGTCTCAGAAGTGTTCAGAGCCCAAGATGGAATGGAAGGTGAAAATTAGGAGCGACGGGACACGGTACATCACAAAGAGACCCGTG
CGAGACCGAATCCTGAAGGAACGTGCCTTAAAGATCAAGGAAGAGCGGAGTGGCATGACCACAGACGATGACACCATGAGCGAGATGAAA
ATGGGGCGCTACTGGAGCAAAGAGGAGAGAAAGCAGCACCTGGTTAGGGCCAAAGAGCAGCGCCGTCGCCGTGAGTTCATGATGCGAAGC
AGGTTAGAGTGTCTCAAGGAGAGCCCTCAGAGCGGCAGTGAGGGCAAGAAGGAGATCAATATCATTGAACTGAGTCACAAAAAGATGATG
AAAAAGAGAAACAAGAAAATTTTGGACAACTGGATGACAATCCAAGAACTGATGACCCATGGGGCCAAGTCTCCAGATGGCACGAGAGTC
CATAATGCCTTCTTGTCGGTGACCACTGTATGACCGAATGAATGGAATGCATGCGACTGATTTTAGGAGGATGCTACCAGTTTCGGTAGA
GTATGATTGCCTCGTTCAATGTGGCGTTTTTATATATATTTTGTGACTCTTTATAGTTTAAATTTTTTGTAAGCAAAAAATACCTGGTAA

>31004_31004_2_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000338382_PDZRN4_chr12_41946458_ENST00000402685_length(amino acids)=1120AA_BP=484
MSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILN
LIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHPLITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWY
LYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCCDIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSL
QLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALLLLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILS
STALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVCPVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPA
PAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQI
NGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSS
NNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQDTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCK
IRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQNIMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIME
HPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNLRSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKL
PDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPV
RDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLECLKESPQSGSEGKKEINIIELSHKKMM

--------------------------------------------------------------
>31004_31004_3_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000338382_PDZRN4_chr12_41946458_ENST00000539469_length(transcript)=3805nt_BP=1455nt
ATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCTAAAG
GAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAATGTA
GTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACTCAAC
TTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGGTGGG
GAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCCAGTG
TTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTGGTAT
CTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTGTGAC
AAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACAGACA
ACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAGTCTT
CAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACTTCTG
AAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTTAAAT
CTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACTATCT
TCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACAGCAG
GAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTGGAGG
ATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCCTGCG
CCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGCCCAA
GCAGATTCCTCCCAGGAGGTCGAGTTGTGTCGTGTTAGCAGTCAAGAGAAGCTGGGCCTGACAGTCTGTTACCGAACAGATGATGAAGAA
GACACCGGCATTTATGTCAGCGAGGTTGACCCAAATAGCATTGCTGCCAAAGACGGCCGGATTCGAGAAGGGGATCGGATTTTGCAAATA
AATGGGGAAGATGTCCAGAATCGAGAAGAAGCAGTGGCCTTGCTGTCTAACGATGAGTGTAAGAGAATCGTGCTGCTTGTTGCAAGGCCA
GAGATTCAGCTGGATGAAGGCTGGCTGGAAGATGAAAGGAATGAATTCTTAGAGGAGTTAAACTTGGAGATGTTGGAAGAAGAGCATAAT
GAAGCAATGCAGCCCACTGCCAATGAGGTGGAGCAGCCAAAAAAGCAAGAAGAAGAAGAAGGCACAACAGACACTGCAACATCCTCATCC
AACAACCATGAGAAGGACAGTGGAGTAGGACGTACAGATGAAAGCTTGCGAAATGATGAGAGCTCAGAGCAGGAGAATGCAGCCGAGGAC
CCCAATAGCACATCTTTGAAGAGCAAGAGAGACCTGGGGCAGAGCCAAGACACTCTGGGAAGTGTTGAACTTCAGTACAATGAGAGCCTC
GTATCTGGTGAATACATTGACTCAGACTGCATTGGCAACCCAGATGAGGACTGTGAAAGATTCAGGCAGCTCTTGGAGCTCAAATGCAAG
ATTCGAAATCATGGAGAGTATGACCTGTATTACTCAAGCAGCACAATTGAATGCAATCAAGGGGAGCAAGAGGGAGTGGAGCATGAGCTA
CAGTTGCTTAATGAAGAACTGAGAAACATTGAGCTTGAGTGTCAGAATATCATGCAGGCTCACAGGCTCCAGAAAGTGACAGACCAGTAT
GGAGACATCTGGACATTGCATGATGGAGGATTCCGGAATTATAACACCAGCATAGATATGCAAAGGGGAAAGCTAGATGACATCATGGAG
CATCCAGAAAAGTCTGACAAGGACAGTTCTAGTGCTTACAACACAGCTGAGAGCTGCAGAAGTACTCCGCTCACTGTAGACCGTTCCCCT
GACAGTTCCCTTCCAAGGGTGATCAACCTCACCAATAAGAAAAACCTGAGAAGCACAATGGCAGCCACCCAGTCCTCTTCCGGACAGAGC
AGTAAAGAGTCGACCTCCACCAAAGCCAAAACCACTGAGCAAGGTTGTAGCGCTGAAAGCAAGGAGAAGGTTTTAGAAGGCAGCAAGCTT
CCTGATCAAGAGAAGGCAGTCAGCGAACACATCCCTTACCTCTCTCCTTACCACAGCTCCTCATATAGATATGCAAACATCCCAGCACAC
GCCCGGCATTATCAAAGCTACATGCAGTTAATTCAACAGAAATCTGCAGTCGAGTATGCTCAGAGTCAGCTCAGCTTGGTGAGCATGTGC
AAGGAGTCTCAGAAGTGTTCAGAGCCCAAGATGGAATGGAAGGTGAAAATTAGGAGCGACGGGACACGGTACATCACAAAGAGACCCGTG
CGAGACCGAATCCTGAAGGAACGTGCCTTAAAGATCAAGGAAGAGCGGAGTGGCATGACCACAGACGATGACACCATGAGCGAGATGAAA
ATGGGGCGCTACTGGAGCAAAGAGGAGAGAAAGCAGCACCTGGTTAGGGCCAAAGAGCAGCGCCGTCGCCGTGAGTTCATGATGCGAAGC
AGGTTAGAGTGTCTCAAGGAGAGCCCTCAGAGCGGCAGTGAGGGCAAGAAGGAGATCAATATCATTGAACTGAGTCACAAAAAGATGATG
AAAAAGAGAAACAAGAAAATTTTGGACAACTGGATGACAATCCAAGAACTGATGACCCATGGGGCCAAGTCTCCAGATGGCACGAGAGTC
CATAATGCCTTCTTGTCGGTGACCACTGTATGACCGAATGAATGGAATGCATGCGACTGATTTTAGGAGGATGCTACCAGTTTCGGTAGA
GTATGATTGCCTCGTTCAATGTGGCGTTTTTATATATATTTTGTGACTCTTTATAGTTTAAATTTTTTGTAAGCAAAAAATACCTGGTAA
TTTTTCATTTGTTTTTCATATACTGGTACCTTCTTTTTGGCTGAGATCTTTCTTTTACTTGTGATATATTCATATTACTCGTTTATAAAA
AATCAAAAACAAAAGGAAAGAAAACAAAAAAAACTTGCACAAAAATACTGAGGAGCCAATTAATTTCCTACTTCAATGTATCTAATGTAA
GTGAAAATCTGGATTTATTTCTCTAGTTTACTTATTTTCTACTTTAATAATAACTCAATGCCAAAATATTTCTATGCTTGTTTCTTGGCA

>31004_31004_3_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000338382_PDZRN4_chr12_41946458_ENST00000539469_length(amino acids)=1120AA_BP=484
MSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILN
LIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHPLITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWY
LYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCCDIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSL
QLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALLLLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILS
STALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVCPVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPA
PAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQI
NGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEFLEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSS
NNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQDTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCK
IRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQNIMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIME
HPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNLRSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKL
PDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSAVEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPV
RDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRREFMMRSRLECLKESPQSGSEGKKEINIIELSHKKMM

--------------------------------------------------------------
>31004_31004_4_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000380249_PDZRN4_chr12_41946458_ENST00000298919_length(transcript)=4419nt_BP=1819nt
GTTCGAGCTTCCCGGCTGCTTTGTTTACCTAATCAAGCCTGGGCAATGGCGGGCGCCCCTCCCGCAGCCTCGCTGCCGCCTTGCAGGTTG
ATCTCAGACTGCTGTGCTAGCAATCAGTGAGACTCCGTGGGCGTAGGACTCTCCAAGCCAGTGAGATGAACTCGGTATCTCAGATGGAAA
TGCAGAAATCACCGTCTTCTCCATCGCTCACGCTGGGAGCTGTAGACCGGAGCTGTTCCTATTCGGCCATCTTTGCTCCTCCCTGCAACT
AACTCCATTCTTAATTGACCATCAAGGAAATTTCCATCCACACAGATTAGCAGTTGAAAATGAAGCTGCACACATACATGTAAGAGAAGC
AAAAATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCT
AAAGGAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAA
TGTAGTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACT
CAACTTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGG
TGGGGAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCC
AGTGTTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTG
GTATCTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTG
TGACAAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACA
GACAACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAG
TCTTCAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACT
TCTGAAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTT
AAATCTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACT
ATCTTCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACA
GCAGGAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTG
GAGGATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCC
TGCGCCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGC
CCAAGCAGATTCCTCCCAGGAGGTCGAGTTGTGTCGTGTTAGCAGTCAAGAGAAGCTGGGCCTGACAGTCTGTTACCGAACAGATGATGA
AGAAGACACCGGCATTTATGTCAGCGAGGTTGACCCAAATAGCATTGCTGCCAAAGACGGCCGGATTCGAGAAGGGGATCGGATTTTGCA
AATAAATGGGGAAGATGTCCAGAATCGAGAAGAAGCAGTGGCCTTGCTGTCTAACGATGAGTGTAAGAGAATCGTGCTGCTTGTTGCAAG
GCCAGAGATTCAGCTGGATGAAGGCTGGCTGGAAGATGAAAGGAATGAATTCTTAGAGGAGTTAAACTTGGAGATGTTGGAAGAAGAGCA
TAATGAAGCAATGCAGCCCACTGCCAATGAGGTGGAGCAGCCAAAAAAGCAAGAAGAAGAAGAAGGCACAACAGACACTGCAACATCCTC
ATCCAACAACCATGAGAAGGACAGTGGAGTAGGACGTACAGATGAAAGCTTGCGAAATGATGAGAGCTCAGAGCAGGAGAATGCAGCCGA
GGACCCCAATAGCACATCTTTGAAGAGCAAGAGAGACCTGGGGCAGAGCCAAGACACTCTGGGAAGTGTTGAACTTCAGTACAATGAGAG
CCTCGTATCTGGTGAATACATTGACTCAGACTGCATTGGCAACCCAGATGAGGACTGTGAAAGATTCAGGCAGCTCTTGGAGCTCAAATG
CAAGATTCGAAATCATGGAGAGTATGACCTGTATTACTCAAGCAGCACAATTGAATGCAATCAAGGGGAGCAAGAGGGAGTGGAGCATGA
GCTACAGTTGCTTAATGAAGAACTGAGAAACATTGAGCTTGAGTGTCAGAATATCATGCAGGCTCACAGGCTCCAGAAAGTGACAGACCA
GTATGGAGACATCTGGACATTGCATGATGGAGGATTCCGGAATTATAACACCAGCATAGATATGCAAAGGGGAAAGCTAGATGACATCAT
GGAGCATCCAGAAAAGTCTGACAAGGACAGTTCTAGTGCTTACAACACAGCTGAGAGCTGCAGAAGTACTCCGCTCACTGTAGACCGTTC
CCCTGACAGTTCCCTTCCAAGGGTGATCAACCTCACCAATAAGAAAAACCTGAGAAGCACAATGGCAGCCACCCAGTCCTCTTCCGGACA
GAGCAGTAAAGAGTCGACCTCCACCAAAGCCAAAACCACTGAGCAAGGTTGTAGCGCTGAAAGCAAGGAGAAGGTTTTAGAAGGCAGCAA
GCTTCCTGATCAAGAGAAGGCAGTCAGCGAACACATCCCTTACCTCTCTCCTTACCACAGCTCCTCATATAGATATGCAAACATCCCAGC
ACACGCCCGGCATTATCAAAGCTACATGCAGTTAATTCAACAGAAATCTGCAGTCGAGTATGCTCAGAGTCAGCTCAGCTTGGTGAGCAT
GTGCAAGGAGTCTCAGAAGTGTTCAGAGCCCAAGATGGAATGGAAGGTGAAAATTAGGAGCGACGGGACACGGTACATCACAAAGAGACC
CGTGCGAGACCGAATCCTGAAGGAACGTGCCTTAAAGATCAAGGAAGAGCGGAGTGGCATGACCACAGACGATGACACCATGAGCGAGAT
GAAAATGGGGCGCTACTGGAGCAAAGAGGAGAGAAAGCAGCACCTGGTTAGGGCCAAAGAGCAGCGCCGTCGCCGTGAGTTCATGATGCG
AAGCAGGTTAGAGTGTCTCAAGGAGAGCCCTCAGAGCGGCAGTGAGGGCAAGAAGGAGATCAATATCATTGAACTGAGTCACAAAAAGAT
GATGAAAAAGAGAAACAAGAAAATTTTGGACAACTGGATGACAATCCAAGAACTGATGACCCATGGGGCCAAGTCTCCAGATGGCACGAG
AGTCCATAATGCCTTCTTGTCGGTGACCACTGTATGACCGAATGAATGGAATGCATGCGACTGATTTTAGGAGGATGCTACCAGTTTCGG
TAGAGTATGATTGCCTCGTTCAATGTGGCGTTTTTATATATATTTTGTGACTCTTTATAGTTTAAATTTTTTGTAAGCAAAAAATACCTG
GTAATTTTTCATTTGTTTTTCATATACTGGTACCTTCTTTTTGGCTGAGATCTTTCTTTTACTTGTGATATATTCATATTACTCGTTTAT
AAAAAATCAAAAACAAAAGGAAAGAAAACAAAAAAAACTTGCACAAAAATACTGAGGAGCCAATTAATTTCCTACTTCAATGTATCTAAT
GTAAGTGAAAATCTGGATTTATTTCTCTAGTTTACTTATTTTCTACTTTAATAATAACTCAATGCCAAAATATTTCTATGCTTGTTTCTT
GGCATAATACATTTTAAATCAAACCTGTTCGTAATAAATCATGTGCCACATCTTGTCTTACACATAAAAGCCACTGCTTTTAACATCCCA
TTGTACATTTAACACATAAATGGTGTTAACATCCCATTGTACATTTAACACATAAATGGCCATTGTCTTTGTCTCAGTAAAGTGTAGGTG
GACAATCTTCCTGTGATATGTAGTGACATTGGTCATGTAGCTAGATAATTATGGTAATTGTGACAATTAAAGAGAAATAAATTATTGATT

>31004_31004_4_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000380249_PDZRN4_chr12_41946458_ENST00000298919_length(amino acids)=1164AA_BP=528
MFLFGHLCSSLQLTPFLIDHQGNFHPHRLAVENEAAHIHVREAKMSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTP
ALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHP
LITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWYLYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCC
DIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSLQLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALL
LLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILSSTALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVC
PVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPAPAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQEVELCRVSSQE
KLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEF
LEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSSNNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQ
DTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCKIRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQN
IMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIMEHPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNL
RSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKLPDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSA
VEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPVRDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVR

--------------------------------------------------------------
>31004_31004_5_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000380249_PDZRN4_chr12_41946458_ENST00000402685_length(transcript)=3955nt_BP=1819nt
GTTCGAGCTTCCCGGCTGCTTTGTTTACCTAATCAAGCCTGGGCAATGGCGGGCGCCCCTCCCGCAGCCTCGCTGCCGCCTTGCAGGTTG
ATCTCAGACTGCTGTGCTAGCAATCAGTGAGACTCCGTGGGCGTAGGACTCTCCAAGCCAGTGAGATGAACTCGGTATCTCAGATGGAAA
TGCAGAAATCACCGTCTTCTCCATCGCTCACGCTGGGAGCTGTAGACCGGAGCTGTTCCTATTCGGCCATCTTTGCTCCTCCCTGCAACT
AACTCCATTCTTAATTGACCATCAAGGAAATTTCCATCCACACAGATTAGCAGTTGAAAATGAAGCTGCACACATACATGTAAGAGAAGC
AAAAATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCT
AAAGGAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAA
TGTAGTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACT
CAACTTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGG
TGGGGAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCC
AGTGTTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTG
GTATCTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTG
TGACAAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACA
GACAACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAG
TCTTCAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACT
TCTGAAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTT
AAATCTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACT
ATCTTCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACA
GCAGGAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTG
GAGGATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCC
TGCGCCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGC
CCAAGCAGATTCCTCCCAGGAGGTCGAGTTGTGTCGTGTTAGCAGTCAAGAGAAGCTGGGCCTGACAGTCTGTTACCGAACAGATGATGA
AGAAGACACCGGCATTTATGTCAGCGAGGTTGACCCAAATAGCATTGCTGCCAAAGACGGCCGGATTCGAGAAGGGGATCGGATTTTGCA
AATAAATGGGGAAGATGTCCAGAATCGAGAAGAAGCAGTGGCCTTGCTGTCTAACGATGAGTGTAAGAGAATCGTGCTGCTTGTTGCAAG
GCCAGAGATTCAGCTGGATGAAGGCTGGCTGGAAGATGAAAGGAATGAATTCTTAGAGGAGTTAAACTTGGAGATGTTGGAAGAAGAGCA
TAATGAAGCAATGCAGCCCACTGCCAATGAGGTGGAGCAGCCAAAAAAGCAAGAAGAAGAAGAAGGCACAACAGACACTGCAACATCCTC
ATCCAACAACCATGAGAAGGACAGTGGAGTAGGACGTACAGATGAAAGCTTGCGAAATGATGAGAGCTCAGAGCAGGAGAATGCAGCCGA
GGACCCCAATAGCACATCTTTGAAGAGCAAGAGAGACCTGGGGCAGAGCCAAGACACTCTGGGAAGTGTTGAACTTCAGTACAATGAGAG
CCTCGTATCTGGTGAATACATTGACTCAGACTGCATTGGCAACCCAGATGAGGACTGTGAAAGATTCAGGCAGCTCTTGGAGCTCAAATG
CAAGATTCGAAATCATGGAGAGTATGACCTGTATTACTCAAGCAGCACAATTGAATGCAATCAAGGGGAGCAAGAGGGAGTGGAGCATGA
GCTACAGTTGCTTAATGAAGAACTGAGAAACATTGAGCTTGAGTGTCAGAATATCATGCAGGCTCACAGGCTCCAGAAAGTGACAGACCA
GTATGGAGACATCTGGACATTGCATGATGGAGGATTCCGGAATTATAACACCAGCATAGATATGCAAAGGGGAAAGCTAGATGACATCAT
GGAGCATCCAGAAAAGTCTGACAAGGACAGTTCTAGTGCTTACAACACAGCTGAGAGCTGCAGAAGTACTCCGCTCACTGTAGACCGTTC
CCCTGACAGTTCCCTTCCAAGGGTGATCAACCTCACCAATAAGAAAAACCTGAGAAGCACAATGGCAGCCACCCAGTCCTCTTCCGGACA
GAGCAGTAAAGAGTCGACCTCCACCAAAGCCAAAACCACTGAGCAAGGTTGTAGCGCTGAAAGCAAGGAGAAGGTTTTAGAAGGCAGCAA
GCTTCCTGATCAAGAGAAGGCAGTCAGCGAACACATCCCTTACCTCTCTCCTTACCACAGCTCCTCATATAGATATGCAAACATCCCAGC
ACACGCCCGGCATTATCAAAGCTACATGCAGTTAATTCAACAGAAATCTGCAGTCGAGTATGCTCAGAGTCAGCTCAGCTTGGTGAGCAT
GTGCAAGGAGTCTCAGAAGTGTTCAGAGCCCAAGATGGAATGGAAGGTGAAAATTAGGAGCGACGGGACACGGTACATCACAAAGAGACC
CGTGCGAGACCGAATCCTGAAGGAACGTGCCTTAAAGATCAAGGAAGAGCGGAGTGGCATGACCACAGACGATGACACCATGAGCGAGAT
GAAAATGGGGCGCTACTGGAGCAAAGAGGAGAGAAAGCAGCACCTGGTTAGGGCCAAAGAGCAGCGCCGTCGCCGTGAGTTCATGATGCG
AAGCAGGTTAGAGTGTCTCAAGGAGAGCCCTCAGAGCGGCAGTGAGGGCAAGAAGGAGATCAATATCATTGAACTGAGTCACAAAAAGAT
GATGAAAAAGAGAAACAAGAAAATTTTGGACAACTGGATGACAATCCAAGAACTGATGACCCATGGGGCCAAGTCTCCAGATGGCACGAG
AGTCCATAATGCCTTCTTGTCGGTGACCACTGTATGACCGAATGAATGGAATGCATGCGACTGATTTTAGGAGGATGCTACCAGTTTCGG
TAGAGTATGATTGCCTCGTTCAATGTGGCGTTTTTATATATATTTTGTGACTCTTTATAGTTTAAATTTTTTGTAAGCAAAAAATACCTG

>31004_31004_5_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000380249_PDZRN4_chr12_41946458_ENST00000402685_length(amino acids)=1164AA_BP=528
MFLFGHLCSSLQLTPFLIDHQGNFHPHRLAVENEAAHIHVREAKMSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTP
ALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHP
LITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWYLYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCC
DIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSLQLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALL
LLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILSSTALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVC
PVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPAPAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQEVELCRVSSQE
KLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEF
LEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSSNNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQ
DTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCKIRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQN
IMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIMEHPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNL
RSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKLPDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSA
VEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPVRDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVR

--------------------------------------------------------------
>31004_31004_6_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000380249_PDZRN4_chr12_41946458_ENST00000539469_length(transcript)=4169nt_BP=1819nt
GTTCGAGCTTCCCGGCTGCTTTGTTTACCTAATCAAGCCTGGGCAATGGCGGGCGCCCCTCCCGCAGCCTCGCTGCCGCCTTGCAGGTTG
ATCTCAGACTGCTGTGCTAGCAATCAGTGAGACTCCGTGGGCGTAGGACTCTCCAAGCCAGTGAGATGAACTCGGTATCTCAGATGGAAA
TGCAGAAATCACCGTCTTCTCCATCGCTCACGCTGGGAGCTGTAGACCGGAGCTGTTCCTATTCGGCCATCTTTGCTCCTCCCTGCAACT
AACTCCATTCTTAATTGACCATCAAGGAAATTTCCATCCACACAGATTAGCAGTTGAAAATGAAGCTGCACACATACATGTAAGAGAAGC
AAAAATGTCAGATGATATCAGGAAAAGGTTTGAATTTCCAAATTCTCTTATCCAATCACAGGCTGTGGGTCATCTTATTGCTGCAGTCCT
AAAGGAAAATGGTTTTTCAGAAAAGATTCACCAATCTACAAATCAGACTCCTGCTTTGAACTTGCTGTGGGAGAAGTGTTGCAGTGACAA
TGTAGTGGTTCGAACAGCCTGCTGTGAAGGTCTGGTGGCACTCGTTGCTCAGGATCATGCAGAGTTCAGCTATGTTCTCAATGGGATACT
CAACTTGATTCCATCAACCAGAAATACACATGGCTTGATAAAAGCCATTATGCACTTACTACAAATGCAAGCTCTTAAGGAAGGACAAGG
TGGGGAAAAGAATATTCAGAGTATATATACCATTAGAAATCATCCTCATCCTTTGATAACTGTGCTTGAACACAGACCTGATTGCTGGCC
AGTGTTTTTGCAGCAGCTGACAGCGTTTTTCCAGCAGTGCCCTGAAAGGTTAGAAGTTTCATGCATTCAAATAATGGCACCATTTCTGTG
GTATCTGTATTGTGAACCATCTCAGTTACAAGAATATGCTAAACTCCGACTAGCCCTGCTGAAAGTCTTACTTCAACCCCAGGTTCTTTG
TGACAAAGATCAACCATCAATACTGGAACAGCAGATACTTCAACTGTGTTGTGACATAGTTCCATGTTTGCAGGTAAAAGATTTGATACA
GACAACAGAGGCGATGATGTTTATTGAGGAAGTATGTTTAAGCCTTTTGCGTCATCCTGTTTTCTGGAAAATTCAGCTTACCCAGATGAG
TCTTCAGCTGCTGTGTGTCAGTGAAGTCAGCTTAAAGATAACTGGTGAATGTTCATCTTCAATTCACCTTTTAGAGCACAGTGTTGAACT
TCTGAAGGAGGATTTTCCTGTTGAACTGGTCATAATTGGAATAGCTTTACTACTTCTACAGACTCCAGCAAGTCAGCAGAAGCCAATCTT
AAATCTAGCTTTGAAGCTCCTCTCTGTTACTGAGGATCAGAAAATCCCAAAGTCCTCTCTGCTGCTAGTGATGCCAATTCTGCAGATACT
ATCTTCTACTGCCTTGGAAGACTGTATATCTGTGGATGAAGAAGGTCCCTCTAGGCAGCAGTTGGCTCTAAACCTTTTGGAAATGATACA
GCAGGAATGTTACAGAGATGACCACCAAAAGCTCTCCTACAAGCTTGTGTGCCCTGTAACCAGTATGTATGGTACAATATTTACAGCCTG
GAGGATTCTTGAAGTAATGACAGACTCGTCTGCTGCAAGTGACTGGTTGGCTTCAGTAGAGTCATTGCTTCCTATTACTGCTGTGATCCC
TGCGCCTGCCTTTCTTCTGCTGGCTCACCTCCTTGTTGAAGACAAAGGACAAAATCTTCACCAAATACTCAAGGTCACTACAGAATTAGC
CCAAGCAGATTCCTCCCAGGAGGTCGAGTTGTGTCGTGTTAGCAGTCAAGAGAAGCTGGGCCTGACAGTCTGTTACCGAACAGATGATGA
AGAAGACACCGGCATTTATGTCAGCGAGGTTGACCCAAATAGCATTGCTGCCAAAGACGGCCGGATTCGAGAAGGGGATCGGATTTTGCA
AATAAATGGGGAAGATGTCCAGAATCGAGAAGAAGCAGTGGCCTTGCTGTCTAACGATGAGTGTAAGAGAATCGTGCTGCTTGTTGCAAG
GCCAGAGATTCAGCTGGATGAAGGCTGGCTGGAAGATGAAAGGAATGAATTCTTAGAGGAGTTAAACTTGGAGATGTTGGAAGAAGAGCA
TAATGAAGCAATGCAGCCCACTGCCAATGAGGTGGAGCAGCCAAAAAAGCAAGAAGAAGAAGAAGGCACAACAGACACTGCAACATCCTC
ATCCAACAACCATGAGAAGGACAGTGGAGTAGGACGTACAGATGAAAGCTTGCGAAATGATGAGAGCTCAGAGCAGGAGAATGCAGCCGA
GGACCCCAATAGCACATCTTTGAAGAGCAAGAGAGACCTGGGGCAGAGCCAAGACACTCTGGGAAGTGTTGAACTTCAGTACAATGAGAG
CCTCGTATCTGGTGAATACATTGACTCAGACTGCATTGGCAACCCAGATGAGGACTGTGAAAGATTCAGGCAGCTCTTGGAGCTCAAATG
CAAGATTCGAAATCATGGAGAGTATGACCTGTATTACTCAAGCAGCACAATTGAATGCAATCAAGGGGAGCAAGAGGGAGTGGAGCATGA
GCTACAGTTGCTTAATGAAGAACTGAGAAACATTGAGCTTGAGTGTCAGAATATCATGCAGGCTCACAGGCTCCAGAAAGTGACAGACCA
GTATGGAGACATCTGGACATTGCATGATGGAGGATTCCGGAATTATAACACCAGCATAGATATGCAAAGGGGAAAGCTAGATGACATCAT
GGAGCATCCAGAAAAGTCTGACAAGGACAGTTCTAGTGCTTACAACACAGCTGAGAGCTGCAGAAGTACTCCGCTCACTGTAGACCGTTC
CCCTGACAGTTCCCTTCCAAGGGTGATCAACCTCACCAATAAGAAAAACCTGAGAAGCACAATGGCAGCCACCCAGTCCTCTTCCGGACA
GAGCAGTAAAGAGTCGACCTCCACCAAAGCCAAAACCACTGAGCAAGGTTGTAGCGCTGAAAGCAAGGAGAAGGTTTTAGAAGGCAGCAA
GCTTCCTGATCAAGAGAAGGCAGTCAGCGAACACATCCCTTACCTCTCTCCTTACCACAGCTCCTCATATAGATATGCAAACATCCCAGC
ACACGCCCGGCATTATCAAAGCTACATGCAGTTAATTCAACAGAAATCTGCAGTCGAGTATGCTCAGAGTCAGCTCAGCTTGGTGAGCAT
GTGCAAGGAGTCTCAGAAGTGTTCAGAGCCCAAGATGGAATGGAAGGTGAAAATTAGGAGCGACGGGACACGGTACATCACAAAGAGACC
CGTGCGAGACCGAATCCTGAAGGAACGTGCCTTAAAGATCAAGGAAGAGCGGAGTGGCATGACCACAGACGATGACACCATGAGCGAGAT
GAAAATGGGGCGCTACTGGAGCAAAGAGGAGAGAAAGCAGCACCTGGTTAGGGCCAAAGAGCAGCGCCGTCGCCGTGAGTTCATGATGCG
AAGCAGGTTAGAGTGTCTCAAGGAGAGCCCTCAGAGCGGCAGTGAGGGCAAGAAGGAGATCAATATCATTGAACTGAGTCACAAAAAGAT
GATGAAAAAGAGAAACAAGAAAATTTTGGACAACTGGATGACAATCCAAGAACTGATGACCCATGGGGCCAAGTCTCCAGATGGCACGAG
AGTCCATAATGCCTTCTTGTCGGTGACCACTGTATGACCGAATGAATGGAATGCATGCGACTGATTTTAGGAGGATGCTACCAGTTTCGG
TAGAGTATGATTGCCTCGTTCAATGTGGCGTTTTTATATATATTTTGTGACTCTTTATAGTTTAAATTTTTTGTAAGCAAAAAATACCTG
GTAATTTTTCATTTGTTTTTCATATACTGGTACCTTCTTTTTGGCTGAGATCTTTCTTTTACTTGTGATATATTCATATTACTCGTTTAT
AAAAAATCAAAAACAAAAGGAAAGAAAACAAAAAAAACTTGCACAAAAATACTGAGGAGCCAATTAATTTCCTACTTCAATGTATCTAAT
GTAAGTGAAAATCTGGATTTATTTCTCTAGTTTACTTATTTTCTACTTTAATAATAACTCAATGCCAAAATATTTCTATGCTTGTTTCTT

>31004_31004_6_FOCAD-PDZRN4_FOCAD_chr9_20789607_ENST00000380249_PDZRN4_chr12_41946458_ENST00000539469_length(amino acids)=1164AA_BP=528
MFLFGHLCSSLQLTPFLIDHQGNFHPHRLAVENEAAHIHVREAKMSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTP
ALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHP
LITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWYLYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCC
DIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSLQLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALL
LLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILSSTALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVC
PVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPAPAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQEVELCRVSSQE
KLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQLDEGWLEDERNEF
LEELNLEMLEEEHNEAMQPTANEVEQPKKQEEEEGTTDTATSSSNNHEKDSGVGRTDESLRNDESSEQENAAEDPNSTSLKSKRDLGQSQ
DTLGSVELQYNESLVSGEYIDSDCIGNPDEDCERFRQLLELKCKIRNHGEYDLYYSSSTIECNQGEQEGVEHELQLLNEELRNIELECQN
IMQAHRLQKVTDQYGDIWTLHDGGFRNYNTSIDMQRGKLDDIMEHPEKSDKDSSSAYNTAESCRSTPLTVDRSPDSSLPRVINLTNKKNL
RSTMAATQSSSGQSSKESTSTKAKTTEQGCSAESKEKVLEGSKLPDQEKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQLIQQKSA
VEYAQSQLSLVSMCKESQKCSEPKMEWKVKIRSDGTRYITKRPVRDRILKERALKIKEERSGMTTDDDTMSEMKMGRYWSKEERKQHLVR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FOCAD-PDZRN4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FOCAD-PDZRN4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FOCAD-PDZRN4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource