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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FOS-MAST2 (FusionGDB2 ID:31036)

Fusion Gene Summary for FOS-MAST2

check button Fusion gene summary
Fusion gene informationFusion gene name: FOS-MAST2
Fusion gene ID: 31036
HgeneTgene
Gene symbol

FOS

MAST2

Gene ID

2353

23139

Gene nameFos proto-oncogene, AP-1 transcription factor subunitmicrotubule associated serine/threonine kinase 2
SynonymsAP-1|C-FOS|p55MAST205|MTSSK
Cytomap

14q24.3

1p34.1

Type of geneprotein-codingprotein-coding
Descriptionproto-oncogene c-FosFBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS)FBJ murine osteosarcoma viral oncogene homologFos proto-oncogene, AP-1 trancription factor subunitG0/G1 switch regulatory protein 7activator protein 1cellular omicrotubule-associated serine/threonine-protein kinase 2microtubule associated testis specific serine/threonine protein kinase
Modification date2020032920200313
UniProtAcc

P01100

Q6P0Q8

Ensembl transtripts involved in fusion geneENST00000303562, ENST00000535987, 
ENST00000555347, ENST00000555686, 
ENST00000554617, ENST00000555242, 
ENST00000556324, 		ENST00000477968, 
ENST00000361297, ENST00000372009, 
Fusion gene scores* DoF score6 X 9 X 1=5414 X 16 X 10=2240
# samples 917
** MAII scorelog2(9/54*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(17/2240*10)=-3.71989208080727
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FOS [Title/Abstract] AND MAST2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFOS(75747698)-MAST2(46496700), # samples:1
Anticipated loss of major functional domain due to fusion event.FOS-MAST2 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
FOS-MAST2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
FOS-MAST2 seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFOS

GO:0007179

transforming growth factor beta receptor signaling pathway

9732876

HgeneFOS

GO:0034614

cellular response to reactive oxygen species

17217916

HgeneFOS

GO:0045893

positive regulation of transcription, DNA-templated

9732876

HgeneFOS

GO:0045944

positive regulation of transcription by RNA polymerase II

10508860

HgeneFOS

GO:0060395

SMAD protein signal transduction

9732876


check buttonFusion gene breakpoints across FOS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MAST2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABF904848FOSchr14

75747698

+MAST2chr1

46496700

+


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Fusion Gene ORF analysis for FOS-MAST2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000303562ENST00000477968FOSchr14

75747698

+MAST2chr1

46496700

+
5CDS-intronENST00000535987ENST00000477968FOSchr14

75747698

+MAST2chr1

46496700

+
5CDS-intronENST00000555347ENST00000477968FOSchr14

75747698

+MAST2chr1

46496700

+
5CDS-intronENST00000555686ENST00000477968FOSchr14

75747698

+MAST2chr1

46496700

+
Frame-shiftENST00000555347ENST00000361297FOSchr14

75747698

+MAST2chr1

46496700

+
Frame-shiftENST00000555347ENST00000372009FOSchr14

75747698

+MAST2chr1

46496700

+
In-frameENST00000303562ENST00000361297FOSchr14

75747698

+MAST2chr1

46496700

+
In-frameENST00000303562ENST00000372009FOSchr14

75747698

+MAST2chr1

46496700

+
In-frameENST00000535987ENST00000361297FOSchr14

75747698

+MAST2chr1

46496700

+
In-frameENST00000535987ENST00000372009FOSchr14

75747698

+MAST2chr1

46496700

+
In-frameENST00000555686ENST00000361297FOSchr14

75747698

+MAST2chr1

46496700

+
In-frameENST00000555686ENST00000372009FOSchr14

75747698

+MAST2chr1

46496700

+
intron-3CDSENST00000554617ENST00000361297FOSchr14

75747698

+MAST2chr1

46496700

+
intron-3CDSENST00000554617ENST00000372009FOSchr14

75747698

+MAST2chr1

46496700

+
intron-3CDSENST00000555242ENST00000361297FOSchr14

75747698

+MAST2chr1

46496700

+
intron-3CDSENST00000555242ENST00000372009FOSchr14

75747698

+MAST2chr1

46496700

+
intron-3CDSENST00000556324ENST00000361297FOSchr14

75747698

+MAST2chr1

46496700

+
intron-3CDSENST00000556324ENST00000372009FOSchr14

75747698

+MAST2chr1

46496700

+
intron-intronENST00000554617ENST00000477968FOSchr14

75747698

+MAST2chr1

46496700

+
intron-intronENST00000555242ENST00000477968FOSchr14

75747698

+MAST2chr1

46496700

+
intron-intronENST00000556324ENST00000477968FOSchr14

75747698

+MAST2chr1

46496700

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000303562FOSchr1475747698+ENST00000372009MAST2chr146496700+4252194519394251771
ENST00000303562FOSchr1475747698+ENST00000361297MAST2chr146496700+4670194519394611890
ENST00000535987FOSchr1475747698+ENST00000372009MAST2chr146496700+3496118912283495756
ENST00000535987FOSchr1475747698+ENST00000361297MAST2chr146496700+3914118912283855875
ENST00000555686FOSchr1475747698+ENST00000372009MAST2chr146496700+3590128313223589756
ENST00000555686FOSchr1475747698+ENST00000361297MAST2chr146496700+4008128313223949875

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000303562ENST00000372009FOSchr1475747698+MAST2chr146496700+0.02853930.9714607
ENST00000303562ENST00000361297FOSchr1475747698+MAST2chr146496700+0.040742970.95925707
ENST00000535987ENST00000372009FOSchr1475747698+MAST2chr146496700+0.061272570.93872744
ENST00000535987ENST00000361297FOSchr1475747698+MAST2chr146496700+0.0351418220.9648582
ENST00000555686ENST00000372009FOSchr1475747698+MAST2chr146496700+0.0498517640.9501482
ENST00000555686ENST00000361297FOSchr1475747698+MAST2chr146496700+0.0315401960.9684598

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Fusion Genomic Features for FOS-MAST2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FOS-MAST2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:75747698/chr1:46496700)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FOS

P01100

MAST2

Q6P0Q8

FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. {ECO:0000269|PubMed:16055710, ECO:0000269|PubMed:17160021, ECO:0000269|PubMed:22105363, ECO:0000269|PubMed:7588633, ECO:0000269|PubMed:9732876}.FUNCTION: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMAST2chr14:75747698chr1:46496700ENST000003612970291104_119201799.0DomainPDZ
TgeneMAST2chr14:75747698chr1:46496700ENST00000361297029512_78501799.0DomainProtein kinase
TgeneMAST2chr14:75747698chr1:46496700ENST00000361297029786_85401799.0DomainAGC-kinase C-terminal
TgeneMAST2chr14:75747698chr1:46496700ENST00000361297029518_52601799.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOSchr14:75747698chr1:46496700ENST00000303562+14137_2000381.0DomainbZIP
HgeneFOSchr14:75747698chr1:46496700ENST00000303562+14139_1590381.0RegionNote=Basic motif%3B required for the activation of phospholipid synthesis%2C but not for CDS1-binding
HgeneFOSchr14:75747698chr1:46496700ENST00000303562+14165_1930381.0RegionLeucine-zipper


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Fusion Gene Sequence for FOS-MAST2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>31036_31036_1_FOS-MAST2_FOS_chr14_75747698_ENST00000303562_MAST2_chr1_46496700_ENST00000361297_length(transcript)=4670nt_BP=1945nt
ACTCATTCATAAAACGCTTGTTATAAAAGCAGTGGCTGCGGCGCCTCGTACTCCAACCGCATCTGCAGCGAGCATCTGAGAAGCCAAGAC
TGAGCCGGCGGCCGCGGCGCAGCGAACGAGCAGTGACCGTGCTCCTACCCAGCTCTGCTCCACAGCGCCCACCTGTCTCCGCCCCTCGGC
CCCTCGCCCGGCTTTGCCTAACCGCCACGATGATGTTCTCGGGCTTCAACGCAGACTACGAGGCGTCATCCTCCCGCTGCAGCAGCGCGT
CCCCGGCCGGGGATAGCCTCTCTTACTACCACTCACCCGCAGACTCCTTCTCCAGCATGGGCTCGCCTGTCAACGCGCAGGACTTCTGCA
CGGACCTGGCCGTCTCCAGTGCCAACTTCATTCCCACGGTCACTGCCATCTCGACCAGTCCGGACCTGCAGTGGCTGGTGCAGCCCGCCC
TCGTCTCCTCCGTGGCCCCATCGCAGACCAGAGCCCCTCACCCTTTCGGAGTCCCCGCCCCCTCCGCTGGGGCTTACTCCAGGGCTGGCG
TTGTGAAGACCATGACAGGAGGCCGAGCGCAGAGCATTGGCAGGAGGGGCAAGGTGGAACAGTTATCTCCAGAAGAAGAAGAGAAAAGGA
GAATCCGAAGGGAAAGGAATAAGATGGCTGCAGCCAAATGCCGCAACCGGAGGAGGGAGCTGACTGATACACTCCAAGCGTTCACCCTGC
CTCTCCTCAATGACCCTGAGCCCAAGCCCTCAGTGGAACCTGTCAAGAGCATCAGCAGCATGGAGCTGAAGACCGAGCCCTTTGATGACT
TCCTGTTCCCAGCATCATCCAGGCCCAGTGGCTCTGAGACAGCCCGCTCCGTGCCAGACATGGACCTATCTGGGTCCTTCTATGCAGCAG
ACTGGGAGCCTCTGCACAGTGGCTCCCTGGGGATGGGGCCCATGGCCACAGAGCTGGAGCCCCTGTGCACTCCGGTGGTCACCTGTACTC
CCAGCTGCACTGCTTACACGTCTTCCTTCGTCTTCACCTACCCCGAGGCTGACTCCTTCCCCAGCTGTGCAGCTGCCCACCGCAAGGGCA
GCAGCAGCAATGAGCCTTCCTCTGACTCGCTCAGCTCACCCACGCTGCTGGCCCTGTGAGGGGGCAGGGAAGGGGAGGCAGCCGGCACCC
ACAAGTGCCACTGCCCGAGCTGGTGCATTACAGAGAGGAGAAACACATCTTCCCTAGAGGGTTCCTGTAGACCTAGGGAGGACCTTATCT
GTGCGTGAAACACACCAGGCTGTGGGCCTCAAGGACTTGAAAGCATCCATGTGTGGACTCAAGTCCTTACCTCTTCCGGAGATGTAGCAA
AACGCATGGAGTGTGTATTGTTCCCAGTGACACTTCAGAGAGCTGGTAGTTAGTAGCATGTTGAGCCAGGCCTGGGTCTGTGTCTCTTTT
CTCTTTCTCCTTAGTCTTCTCATAGCATTAACTAATCTATTGGGTTCATTATTGGAATTAACCTGGTGCTGGATATTTTCAAATTGTATC
TAGTGCAGCTGATTTTAACAATAACTACTGTGTTCCTGGCAATAGTGTGTTCTGATTAGAAATGACCAATATTATACTAAGAAAAGATAC
GACTTTATTTTCTGGTAGATAGAAATAAATAGCTATATCCATGTACTGTAGTTTTTCTTCAACATCAATGTTCATTGTAATGTTACTGAT
CATGCATTGTTGAGGTGGTCTGAATGTTCTGACATTAACAGTTTTCCATGAAAACGTTTTATTGTGTTTTTAATTTATTTATTAAGATGG
ATTCTCAGATATTTATATTTTTATTTTATTTTTTTCTACCTTGAGGTCTTTTGACATGTGGAAAGTGAATTTGAATGAAAAATTTAAGCA
TTGTTTGCTTATTGTTCCAAGACATTGTCAATAAAAGCATTTAAGTTGAATGCGATCTGAGTCATCCCACACAGAGAGTGACTCAAGCCC
TCCAATGACAGTGCGACGCCGCTGCTCAGGCCTCCTGGATGCGCCTCGGTTCCCGGAGGGCCCTGAGGAGGCCAGCAGCACCCTCAGGAG
GCAACCACAGGAGGGTATATGGGTCCTGACACCCCCATCTGGAGAGGGGGTATCTGGGCCTGTCACTGAACACTCAGGGGAGCAGCGGCC
AAAGCTGGATGAGGAAGCTGTTGGCCGGAGCAGTGGTTCCAGTCCAGCTATGGAGACCCGAGGCCGTGGGACCTCACAGCTGGCTGAGGG
AGCCACAGCCAAGGCCATCAGTGACCTGGCTGTGCGTAGGGCCCGCCACCGGCTGCTCTCTGGGGACTCAACAGAGAAGCGCACTGCTCG
CCCTGTCAACAAAGTGATCAAGTCCGCCTCAGCCACAGCCCTCTCACTCCTCATTCCTTCGGAACACCACACCTGCTCCCCGTTGGCCAG
CCCCATGTCCCCACATTCTCAGTCGTCCAACCCATCATCCCGGGACTCTTCTCCAAGCAGGGACTTCTTGCCAGCCCTTGGCAGCATGAG
GCCTCCCATCATCATCCACCGAGCTGGCAAGAAGTATGGCTTCACCCTGCGGGCCATTCGCGTCTACATGGGTGACTCCGATGTCTACAC
CGTGCACCATATGGTGTGGCACGTGGAGGATGGAGGTCCGGCCAGTGAGGCAGGGCTTCGTCAAGGTGACCTCATCACCCATGTCAATGG
GGAACCTGTGCATGGCCTGGTGCACACGGAGGTGGTAGAGCTGATCCTGAAGAGTGGAAACAAGGTGGCCATTTCAACAACTCCCCTGGA
GAACACATCCATTAAAGTGGGGCCAGCTCGGAAGGGCAGCTACAAGGCCAAGATGGCCCGAAGGAGCAAGAGGAGCCGCGGCAAGGATGG
GCAAGAAAGCAGAAAAAGGAGCTCCCTGTTCCGCAAGATCACCAAGCAAGCATCCCTGCTCCACACCAGCCGCAGCCTTTCTTCCCTTAA
CCGCTCCTTGTCATCAGGGGAGAGTGGGCCAGGCTCTCCCACACACAGCCACAGCCTTTCCCCCCGATCTCCCACTCAAGGCTACCGGGT
GACCCCCGATGCTGTGCATTCAGTGGGAGGGAATTCATCACAGAGCAGCTCCCCCAGCTCCAGCGTGCCCAGTTCCCCAGCCGGCTCTGG
GCACACACGGCCCAGCTCCCTCCACGGTCTGGCACCCAAGCTCCAACGCCAGTACCGCTCTCCACGGCGCAAGTCAGCAGGCAGCATCCC
ACTGTCACCACTGGCCCACACCCCTTCTCCCCCACCCCCAACAGCTTCACCTCAGCGGTCCCCATCGCCCCTGTCTGGCCATGTAGCCCA
GGCCTTTCCCACAAAGCTTCACTTGTCACCTCCCCTGGGCAGGCAACTCTCACGGCCCAAGAGTGCGGAGCCACCCCGTTCACCACTACT
CAAGAGGGTGCAGTCGGCTGAGAAACTGGCAGCAGCACTTGCCGCCTCTGAGAAGAAGCTAGCCACTTCTCGCAAGCACAGCCTTGACCT
GCCCCACTCTGAACTAAAGAAGGAACTGCCGCCCAGGGAAGTGAGCCCTCTGGAGGTAGTTGGAGCCAGGAGTGTGCTGTCTGGCAAGGG
GGCCCTGCCAGGGAAGGGGGTGCTGCAGCCTGCTCCCTCACGGGCCCTAGGCACCCTCCGGCAGGACCGAGCCGAACGACGGGAGTCGCT
GCAGAAGCAAGAAGCCATTCGTGAGGTGGACTCCTCAGAGGACGACACCGAGGAAGGGCCTGAGAACAGCCAGGGTGCACAGGAGCTGAG
CTTGGCACCTCACCCAGAAGTGAGCCAGAGTGTGGCCCCTAAAGGAGCAGGAGAGAGTGGGGAAGAGGATCCTTTCCCGTCCAGAGACCC
TAGGAGCCTGGGCCCAATGGTCCCAAGCCTATTGACAGGGATCACACTGGGGCCTCCCAGAATGGAAAGTCCCAGTGGTCCCCACAGGAG
GCTCGGGAGCCCACAAGCCATTGAGGAGGCTGCCAGCTCCTCCTCAGCAGGCCCCAACCTAGGTCAGTCTGGAGCCACAGACCCCATCCC
TCCTGAAGGTTGCTGGAAGGCCCAGCACCTCCACACCCAGGCACTAACAGCACTTTCTCCCAGCACTTCGGGACTCACCCCCACCAGCAG
TTGCTCTCCTCCCAGCTCCACCTCTGGGAAGCTGAGCATGTGGTCCTGGAAATCCCTTATTGAGGGCCCAGACAGGGCATCCCCAAGCAG
AAAGGCAACCATGGCAGGTGGGCTAGCCAACCTCCAGGATTTGGAAAACACAACTCCAGCCCAGCCTAAGAACCTGTCTCCCAGGGAGCA
GGGGAAGACACAGCCACCTAGTGCCCCCAGACTGGCCCATCCATCTTATGAGGATCCCAGCCAGGGCTGGCTATGGGAGTCTGAGTGTGC
ACAAGCAGTGAAAGAGGATCCAGCCCTGAGCATCACCCAAGTGCCTGATGCCTCAGGTGACAGAAGGCAGGACGTTCCATGCCGAGGCTG
CCCCCTCACCCAGAAGTCTGAGCCCAGCCTCAGGAGGGGCCAAGAACCAGGGGGCCATCAAAAGCATCGGGATTTGGCATTGGTTCCAGA

>31036_31036_1_FOS-MAST2_FOS_chr14_75747698_ENST00000303562_MAST2_chr1_46496700_ENST00000361297_length(amino acids)=890AA_BP=2
MRSESSHTESDSSPPMTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLTPPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPA
METRGRGTSQLAEGATAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMSPHSQSSNPSSRDS
SPSRDFLPALGSMRPPIIIHRAGKKYGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELIL
KSGNKVAISTTPLENTSIKVGPARKGSYKAKMARRSKRSRGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHS
HSLSPRSPTQGYRVTPDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPPPTAS
PQRSPSPLSGHVAQAFPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSP
LEVVGARSVLSGKGALPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTEEGPENSQGAQELSLAPHPEVSQSVAPKGA
GESGEEDPFPSRDPRSLGPMVPSLLTGITLGPPRMESPSGPHRRLGSPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALT
ALSPSTSGLTPTSSCSPPSSTSGKLSMWSWKSLIEGPDRASPSRKATMAGGLANLQDLENTTPAQPKNLSPREQGKTQPPSAPRLAHPSY

--------------------------------------------------------------
>31036_31036_2_FOS-MAST2_FOS_chr14_75747698_ENST00000303562_MAST2_chr1_46496700_ENST00000372009_length(transcript)=4252nt_BP=1945nt
ACTCATTCATAAAACGCTTGTTATAAAAGCAGTGGCTGCGGCGCCTCGTACTCCAACCGCATCTGCAGCGAGCATCTGAGAAGCCAAGAC
TGAGCCGGCGGCCGCGGCGCAGCGAACGAGCAGTGACCGTGCTCCTACCCAGCTCTGCTCCACAGCGCCCACCTGTCTCCGCCCCTCGGC
CCCTCGCCCGGCTTTGCCTAACCGCCACGATGATGTTCTCGGGCTTCAACGCAGACTACGAGGCGTCATCCTCCCGCTGCAGCAGCGCGT
CCCCGGCCGGGGATAGCCTCTCTTACTACCACTCACCCGCAGACTCCTTCTCCAGCATGGGCTCGCCTGTCAACGCGCAGGACTTCTGCA
CGGACCTGGCCGTCTCCAGTGCCAACTTCATTCCCACGGTCACTGCCATCTCGACCAGTCCGGACCTGCAGTGGCTGGTGCAGCCCGCCC
TCGTCTCCTCCGTGGCCCCATCGCAGACCAGAGCCCCTCACCCTTTCGGAGTCCCCGCCCCCTCCGCTGGGGCTTACTCCAGGGCTGGCG
TTGTGAAGACCATGACAGGAGGCCGAGCGCAGAGCATTGGCAGGAGGGGCAAGGTGGAACAGTTATCTCCAGAAGAAGAAGAGAAAAGGA
GAATCCGAAGGGAAAGGAATAAGATGGCTGCAGCCAAATGCCGCAACCGGAGGAGGGAGCTGACTGATACACTCCAAGCGTTCACCCTGC
CTCTCCTCAATGACCCTGAGCCCAAGCCCTCAGTGGAACCTGTCAAGAGCATCAGCAGCATGGAGCTGAAGACCGAGCCCTTTGATGACT
TCCTGTTCCCAGCATCATCCAGGCCCAGTGGCTCTGAGACAGCCCGCTCCGTGCCAGACATGGACCTATCTGGGTCCTTCTATGCAGCAG
ACTGGGAGCCTCTGCACAGTGGCTCCCTGGGGATGGGGCCCATGGCCACAGAGCTGGAGCCCCTGTGCACTCCGGTGGTCACCTGTACTC
CCAGCTGCACTGCTTACACGTCTTCCTTCGTCTTCACCTACCCCGAGGCTGACTCCTTCCCCAGCTGTGCAGCTGCCCACCGCAAGGGCA
GCAGCAGCAATGAGCCTTCCTCTGACTCGCTCAGCTCACCCACGCTGCTGGCCCTGTGAGGGGGCAGGGAAGGGGAGGCAGCCGGCACCC
ACAAGTGCCACTGCCCGAGCTGGTGCATTACAGAGAGGAGAAACACATCTTCCCTAGAGGGTTCCTGTAGACCTAGGGAGGACCTTATCT
GTGCGTGAAACACACCAGGCTGTGGGCCTCAAGGACTTGAAAGCATCCATGTGTGGACTCAAGTCCTTACCTCTTCCGGAGATGTAGCAA
AACGCATGGAGTGTGTATTGTTCCCAGTGACACTTCAGAGAGCTGGTAGTTAGTAGCATGTTGAGCCAGGCCTGGGTCTGTGTCTCTTTT
CTCTTTCTCCTTAGTCTTCTCATAGCATTAACTAATCTATTGGGTTCATTATTGGAATTAACCTGGTGCTGGATATTTTCAAATTGTATC
TAGTGCAGCTGATTTTAACAATAACTACTGTGTTCCTGGCAATAGTGTGTTCTGATTAGAAATGACCAATATTATACTAAGAAAAGATAC
GACTTTATTTTCTGGTAGATAGAAATAAATAGCTATATCCATGTACTGTAGTTTTTCTTCAACATCAATGTTCATTGTAATGTTACTGAT
CATGCATTGTTGAGGTGGTCTGAATGTTCTGACATTAACAGTTTTCCATGAAAACGTTTTATTGTGTTTTTAATTTATTTATTAAGATGG
ATTCTCAGATATTTATATTTTTATTTTATTTTTTTCTACCTTGAGGTCTTTTGACATGTGGAAAGTGAATTTGAATGAAAAATTTAAGCA
TTGTTTGCTTATTGTTCCAAGACATTGTCAATAAAAGCATTTAAGTTGAATGCGATCTGAGTCATCCCACACAGAGAGTGACTCAAGCCC
TCCAATGACAGTGCGACGCCGCTGCTCAGGCCTCCTGGATGCGCCTCGGTTCCCGGAGGGCCCTGAGGAGGCCAGCAGCACCCTCAGGAG
GCAACCACAGGAGGGTATATGGGTCCTGACACCCCCATCTGGAGAGGGGGTATCTGGGCCTGTCACTGAACACTCAGGGGAGCAGCGGCC
AAAGCTGGATGAGGAAGCTGTTGGCCGGAGCAGTGGTTCCAGTCCAGCTATGGAGACCCGAGGCCGTGGGACCTCACAGCTGGCTGAGGG
AGCCACAGCCAAGGCCATCAGTGACCTGGCTGTGCGTAGGGCCCGCCACCGGCTGCTCTCTGGGGACTCAACAGAGAAGCGCACTGCTCG
CCCTGTCAACAAAGTGATCAAGTCCGCCTCAGCCACAGCCCTCTCACTCCTCATTCCTTCGGAACACCACACCTGCTCCCCGTTGGCCAG
CCCCATGTCCCCACATTCTCAGTCGTCCAACCCATCATCCCGGGACTCTTCTCCATATGGCTTCACCCTGCGGGCCATTCGCGTCTACAT
GGGTGACTCCGATGTCTACACCGTGCACCATATGGTGTGGCACGTGGAGGATGGAGGTCCGGCCAGTGAGGCAGGGCTTCGTCAAGGTGA
CCTCATCACCCATGTCAATGGGGAACCTGTGCATGGCCTGGTGCACACGGAGGTGGTAGAGCTGATCCTGAAGAGTGGAAACAAGGTGGC
CATTTCAACAACTCCCCTGGAGAACACATCCATTAAAGTGGGGCCAGCTCGGAAGGGCAGCTACAAGGCCAAGATGGCCCGAAGGAGCAA
GAGGAGCCGCGGCAAGGATGGGCAAGAAAGCAGAAAAAGGAGCTCCCTGTTCCGCAAGATCACCAAGCAAGCATCCCTGCTCCACACCAG
CCGCAGCCTTTCTTCCCTTAACCGCTCCTTGTCATCAGGGGAGAGTGGGCCAGGCTCTCCCACACACAGCCACAGCCTTTCCCCCCGATC
TCCCACTCAAGGCTACCGGGTGACCCCCGATGCTGTGCATTCAGAACTCTCACGGCCCAAGAGTGCGGAGCCACCCCGTTCACCACTACT
CAAGAGGGTGCAGTCGGCTGAGAAACTGGCAGCAGCACTTGCCGCCTCTGAGAAGAAGCTAGCCACTTCTCGCAAGCACAGCCTTGACCT
GCCCCACTCTGAACTAAAGAAGGAACTGCCGCCCAGGGAAGTGAGCCCTCTGGAGGTAGTTGGAGCCAGGAGTGTGCTGTCTGGCAAGGG
GGCCCTGCCAGGGAAGGGGGTGCTGCAGCCTGCTCCCTCACGGGCCCTAGGCACCCTCCGGCAGGACCGAGCCGAACGACGGGAGTCGCT
GCAGAAGCAAGAAGCCATTCGTGAGGTGGACTCCTCAGAGGACGACACCGAGGAAGGGCCTGAGAACAGCCAGGGTGCACAGGAGCTGAG
CTTGGCACCTCACCCAGAAGTGAGCCAGAGTGTGGCCCCTAAAGGAGCAGGAGAGAGTGGGGAAGAGGATCCTTTCCCGTCCAGAGACCC
TAGGAGCCTGGGCCCAATGGTCCCAAGCCTATTGACAGGGATCACACTGGGGCCTCCCAGAATGGAAAGTCCCAGTGGTCCCCACAGGAG
GCTCGGGAGCCCACAAGCCATTGAGGAGGCTGCCAGCTCCTCCTCAGCAGGCCCCAACCTAGGTCAGTCTGGAGCCACAGACCCCATCCC
TCCTGAAGGTTGCTGGAAGGCCCAGCACCTCCACACCCAGGCACTAACAGCACTTTCTCCCAGCACTTCGGGACTCACCCCCACCAGCAG
TTGCTCTCCTCCCAGCTCCACCTCTGGGAAGCTGAGCATGTGGTCCTGGAAATCCCTTATTGAGGGCCCAGACAGGGCATCCCCAAGCAG
AAAGGCAACCATGGCAGGTGGGCTAGCCAACCTCCAGGATTTGGAAAACACAACTCCAGCCCAGCCTAAGAACCTGTCTCCCAGGGAGCA
GGGGAAGACACAGCCACCTAGTGCCCCCAGACTGGCCCATCCATCTTATGAGGATCCCAGCCAGGGCTGGCTATGGGAGTCTGAGTGTGC
ACAAGCAGTGAAAGAGGATCCAGCCCTGAGCATCACCCAAGTGCCTGATGCCTCAGGTGACAGAAGGCAGGACGTTCCATGCCGAGGCTG
CCCCCTCACCCAGAAGTCTGAGCCCAGCCTCAGGAGGGGCCAAGAACCAGGGGGCCATCAAAAGCATCGGGATTTGGCATTGGTTCCAGA

>31036_31036_2_FOS-MAST2_FOS_chr14_75747698_ENST00000303562_MAST2_chr1_46496700_ENST00000372009_length(amino acids)=771AA_BP=2
MRSESSHTESDSSPPMTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLTPPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPA
METRGRGTSQLAEGATAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMSPHSQSSNPSSRDS
SPYGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELILKSGNKVAISTTPLENTSIKVGPA
RKGSYKAKMARRSKRSRGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPTQGYRVTPDAVHSEL
SRPKSAEPPRSPLLKRVQSAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSPLEVVGARSVLSGKGALPGKGVLQPAPSRAL
GTLRQDRAERRESLQKQEAIREVDSSEDDTEEGPENSQGAQELSLAPHPEVSQSVAPKGAGESGEEDPFPSRDPRSLGPMVPSLLTGITL
GPPRMESPSGPHRRLGSPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALTALSPSTSGLTPTSSCSPPSSTSGKLSMWSW
KSLIEGPDRASPSRKATMAGGLANLQDLENTTPAQPKNLSPREQGKTQPPSAPRLAHPSYEDPSQGWLWESECAQAVKEDPALSITQVPD

--------------------------------------------------------------
>31036_31036_3_FOS-MAST2_FOS_chr14_75747698_ENST00000535987_MAST2_chr1_46496700_ENST00000361297_length(transcript)=3914nt_BP=1189nt
AACCGCATCTGCAGCGAGCATCTGAGAAGCCAAGACTGAGCCGGCGGCCGCGGCGCAGCGAACGAGCAGTGACCGTGCTCCTACCCAGCT
CTGCTCCACAGCGCCCACCTGTCTCCGCCCCTCGGCCCCTCGCCCGGCTTTGCCTAACCGCCACGATGATGTTCTCGGGCTTCAACGCAG
ACTACGAGGCGTCATCCTCCCGCTGCAGCAGCGCGTCCCCGGCCGGGGATAGCCTCTCTTACTACCACTCACCCGCAGACTCCTTCTCCA
GCATGGGCTCGCCTGTCAACGCGCAGGACTTCTGCACGGACCTGGCCGTCTCCAGTGCCAACTTCATTCCCACGGTCACTGCCATCTCGA
CCAGTCCGGACCTGCAGTGGCTGGTGCAGCCCGCCCTCGTCTCCTCCGTGGCCCCATCGCAGACCAGAGCCCCTCACCCTTTCGGAGTCC
CCGCCCCCTCCGCTGGGGCTTACTCCAGGGCTGGCGTTGTGAAGACCATGACAGGAGGCCGAGCGCAGAGCATTGGCAGGAGGGGCAAGG
TGGAACAGTTCACCCTGCCTCTCCTCAATGACCCTGAGCCCAAGCCCTCAGTGGAACCTGTCAAGAGCATCAGCAGCATGGAGCTGAAGA
CCGAGCCCTTTGATGACTTCCTGTTCCCAGCATCATCCAGGCCCAGTGGCTCTGAGACAGCCCGCTCCGTGCCAGACATGGACCTATCTG
GGTCCTTCTATGCAGCAGACTGGGAGCCTCTGCACAGTGGCTCCCTGGGGATGGGGCCCATGGCCACAGAGCTGGAGCCCCTGTGCACTC
CGGTGGTCACCTGTACTCCCAGCTGCACTGCTTACACGTCTTCCTTCGTCTTCACCTACCCCGAGGCTGACTCCTTCCCCAGCTGTGCAG
CTGCCCACCGCAAGGGCAGCAGCAGCAATGAGCCTTCCTCTGACTCGCTCAGCTCACCCACGCTGCTGGCCCTGTGAGGGGGCAGGGAAG
GGGAGGCAGCCGGCACCCACAAGTGCCACTGCCCGAGCTGGTGCATTACAGAGAGGAGAAACACATCTTCCCTAGAGGGTTCCTGTAGAC
CTAGGGAGGACCTTATCTGTGCGTGAAACACACCAGGCTGTGGGCCTCAAGGACTTGAAAGCATCCATGTGTGGACTCAAGTCCTTACCT
CTTCCGGAGATGTAGCAAATCTGAGTCATCCCACACAGAGAGTGACTCAAGCCCTCCAATGACAGTGCGACGCCGCTGCTCAGGCCTCCT
GGATGCGCCTCGGTTCCCGGAGGGCCCTGAGGAGGCCAGCAGCACCCTCAGGAGGCAACCACAGGAGGGTATATGGGTCCTGACACCCCC
ATCTGGAGAGGGGGTATCTGGGCCTGTCACTGAACACTCAGGGGAGCAGCGGCCAAAGCTGGATGAGGAAGCTGTTGGCCGGAGCAGTGG
TTCCAGTCCAGCTATGGAGACCCGAGGCCGTGGGACCTCACAGCTGGCTGAGGGAGCCACAGCCAAGGCCATCAGTGACCTGGCTGTGCG
TAGGGCCCGCCACCGGCTGCTCTCTGGGGACTCAACAGAGAAGCGCACTGCTCGCCCTGTCAACAAAGTGATCAAGTCCGCCTCAGCCAC
AGCCCTCTCACTCCTCATTCCTTCGGAACACCACACCTGCTCCCCGTTGGCCAGCCCCATGTCCCCACATTCTCAGTCGTCCAACCCATC
ATCCCGGGACTCTTCTCCAAGCAGGGACTTCTTGCCAGCCCTTGGCAGCATGAGGCCTCCCATCATCATCCACCGAGCTGGCAAGAAGTA
TGGCTTCACCCTGCGGGCCATTCGCGTCTACATGGGTGACTCCGATGTCTACACCGTGCACCATATGGTGTGGCACGTGGAGGATGGAGG
TCCGGCCAGTGAGGCAGGGCTTCGTCAAGGTGACCTCATCACCCATGTCAATGGGGAACCTGTGCATGGCCTGGTGCACACGGAGGTGGT
AGAGCTGATCCTGAAGAGTGGAAACAAGGTGGCCATTTCAACAACTCCCCTGGAGAACACATCCATTAAAGTGGGGCCAGCTCGGAAGGG
CAGCTACAAGGCCAAGATGGCCCGAAGGAGCAAGAGGAGCCGCGGCAAGGATGGGCAAGAAAGCAGAAAAAGGAGCTCCCTGTTCCGCAA
GATCACCAAGCAAGCATCCCTGCTCCACACCAGCCGCAGCCTTTCTTCCCTTAACCGCTCCTTGTCATCAGGGGAGAGTGGGCCAGGCTC
TCCCACACACAGCCACAGCCTTTCCCCCCGATCTCCCACTCAAGGCTACCGGGTGACCCCCGATGCTGTGCATTCAGTGGGAGGGAATTC
ATCACAGAGCAGCTCCCCCAGCTCCAGCGTGCCCAGTTCCCCAGCCGGCTCTGGGCACACACGGCCCAGCTCCCTCCACGGTCTGGCACC
CAAGCTCCAACGCCAGTACCGCTCTCCACGGCGCAAGTCAGCAGGCAGCATCCCACTGTCACCACTGGCCCACACCCCTTCTCCCCCACC
CCCAACAGCTTCACCTCAGCGGTCCCCATCGCCCCTGTCTGGCCATGTAGCCCAGGCCTTTCCCACAAAGCTTCACTTGTCACCTCCCCT
GGGCAGGCAACTCTCACGGCCCAAGAGTGCGGAGCCACCCCGTTCACCACTACTCAAGAGGGTGCAGTCGGCTGAGAAACTGGCAGCAGC
ACTTGCCGCCTCTGAGAAGAAGCTAGCCACTTCTCGCAAGCACAGCCTTGACCTGCCCCACTCTGAACTAAAGAAGGAACTGCCGCCCAG
GGAAGTGAGCCCTCTGGAGGTAGTTGGAGCCAGGAGTGTGCTGTCTGGCAAGGGGGCCCTGCCAGGGAAGGGGGTGCTGCAGCCTGCTCC
CTCACGGGCCCTAGGCACCCTCCGGCAGGACCGAGCCGAACGACGGGAGTCGCTGCAGAAGCAAGAAGCCATTCGTGAGGTGGACTCCTC
AGAGGACGACACCGAGGAAGGGCCTGAGAACAGCCAGGGTGCACAGGAGCTGAGCTTGGCACCTCACCCAGAAGTGAGCCAGAGTGTGGC
CCCTAAAGGAGCAGGAGAGAGTGGGGAAGAGGATCCTTTCCCGTCCAGAGACCCTAGGAGCCTGGGCCCAATGGTCCCAAGCCTATTGAC
AGGGATCACACTGGGGCCTCCCAGAATGGAAAGTCCCAGTGGTCCCCACAGGAGGCTCGGGAGCCCACAAGCCATTGAGGAGGCTGCCAG
CTCCTCCTCAGCAGGCCCCAACCTAGGTCAGTCTGGAGCCACAGACCCCATCCCTCCTGAAGGTTGCTGGAAGGCCCAGCACCTCCACAC
CCAGGCACTAACAGCACTTTCTCCCAGCACTTCGGGACTCACCCCCACCAGCAGTTGCTCTCCTCCCAGCTCCACCTCTGGGAAGCTGAG
CATGTGGTCCTGGAAATCCCTTATTGAGGGCCCAGACAGGGCATCCCCAAGCAGAAAGGCAACCATGGCAGGTGGGCTAGCCAACCTCCA
GGATTTGGAAAACACAACTCCAGCCCAGCCTAAGAACCTGTCTCCCAGGGAGCAGGGGAAGACACAGCCACCTAGTGCCCCCAGACTGGC
CCATCCATCTTATGAGGATCCCAGCCAGGGCTGGCTATGGGAGTCTGAGTGTGCACAAGCAGTGAAAGAGGATCCAGCCCTGAGCATCAC
CCAAGTGCCTGATGCCTCAGGTGACAGAAGGCAGGACGTTCCATGCCGAGGCTGCCCCCTCACCCAGAAGTCTGAGCCCAGCCTCAGGAG
GGGCCAAGAACCAGGGGGCCATCAAAAGCATCGGGATTTGGCATTGGTTCCAGATGAGCTTTTAAAGCAAACATAGCAGTTGTTTGCCAT

>31036_31036_3_FOS-MAST2_FOS_chr14_75747698_ENST00000535987_MAST2_chr1_46496700_ENST00000361297_length(amino acids)=875AA_BP=
MTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLTPPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPAMETRGRGTSQLAEGA
TAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMSPHSQSSNPSSRDSSPSRDFLPALGSMRP
PIIIHRAGKKYGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELILKSGNKVAISTTPLEN
TSIKVGPARKGSYKAKMARRSKRSRGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPTQGYRVT
PDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPPPTASPQRSPSPLSGHVAQA
FPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSPLEVVGARSVLSGKGA
LPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTEEGPENSQGAQELSLAPHPEVSQSVAPKGAGESGEEDPFPSRDPR
SLGPMVPSLLTGITLGPPRMESPSGPHRRLGSPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALTALSPSTSGLTPTSSC
SPPSSTSGKLSMWSWKSLIEGPDRASPSRKATMAGGLANLQDLENTTPAQPKNLSPREQGKTQPPSAPRLAHPSYEDPSQGWLWESECAQ

--------------------------------------------------------------
>31036_31036_4_FOS-MAST2_FOS_chr14_75747698_ENST00000535987_MAST2_chr1_46496700_ENST00000372009_length(transcript)=3496nt_BP=1189nt
AACCGCATCTGCAGCGAGCATCTGAGAAGCCAAGACTGAGCCGGCGGCCGCGGCGCAGCGAACGAGCAGTGACCGTGCTCCTACCCAGCT
CTGCTCCACAGCGCCCACCTGTCTCCGCCCCTCGGCCCCTCGCCCGGCTTTGCCTAACCGCCACGATGATGTTCTCGGGCTTCAACGCAG
ACTACGAGGCGTCATCCTCCCGCTGCAGCAGCGCGTCCCCGGCCGGGGATAGCCTCTCTTACTACCACTCACCCGCAGACTCCTTCTCCA
GCATGGGCTCGCCTGTCAACGCGCAGGACTTCTGCACGGACCTGGCCGTCTCCAGTGCCAACTTCATTCCCACGGTCACTGCCATCTCGA
CCAGTCCGGACCTGCAGTGGCTGGTGCAGCCCGCCCTCGTCTCCTCCGTGGCCCCATCGCAGACCAGAGCCCCTCACCCTTTCGGAGTCC
CCGCCCCCTCCGCTGGGGCTTACTCCAGGGCTGGCGTTGTGAAGACCATGACAGGAGGCCGAGCGCAGAGCATTGGCAGGAGGGGCAAGG
TGGAACAGTTCACCCTGCCTCTCCTCAATGACCCTGAGCCCAAGCCCTCAGTGGAACCTGTCAAGAGCATCAGCAGCATGGAGCTGAAGA
CCGAGCCCTTTGATGACTTCCTGTTCCCAGCATCATCCAGGCCCAGTGGCTCTGAGACAGCCCGCTCCGTGCCAGACATGGACCTATCTG
GGTCCTTCTATGCAGCAGACTGGGAGCCTCTGCACAGTGGCTCCCTGGGGATGGGGCCCATGGCCACAGAGCTGGAGCCCCTGTGCACTC
CGGTGGTCACCTGTACTCCCAGCTGCACTGCTTACACGTCTTCCTTCGTCTTCACCTACCCCGAGGCTGACTCCTTCCCCAGCTGTGCAG
CTGCCCACCGCAAGGGCAGCAGCAGCAATGAGCCTTCCTCTGACTCGCTCAGCTCACCCACGCTGCTGGCCCTGTGAGGGGGCAGGGAAG
GGGAGGCAGCCGGCACCCACAAGTGCCACTGCCCGAGCTGGTGCATTACAGAGAGGAGAAACACATCTTCCCTAGAGGGTTCCTGTAGAC
CTAGGGAGGACCTTATCTGTGCGTGAAACACACCAGGCTGTGGGCCTCAAGGACTTGAAAGCATCCATGTGTGGACTCAAGTCCTTACCT
CTTCCGGAGATGTAGCAAATCTGAGTCATCCCACACAGAGAGTGACTCAAGCCCTCCAATGACAGTGCGACGCCGCTGCTCAGGCCTCCT
GGATGCGCCTCGGTTCCCGGAGGGCCCTGAGGAGGCCAGCAGCACCCTCAGGAGGCAACCACAGGAGGGTATATGGGTCCTGACACCCCC
ATCTGGAGAGGGGGTATCTGGGCCTGTCACTGAACACTCAGGGGAGCAGCGGCCAAAGCTGGATGAGGAAGCTGTTGGCCGGAGCAGTGG
TTCCAGTCCAGCTATGGAGACCCGAGGCCGTGGGACCTCACAGCTGGCTGAGGGAGCCACAGCCAAGGCCATCAGTGACCTGGCTGTGCG
TAGGGCCCGCCACCGGCTGCTCTCTGGGGACTCAACAGAGAAGCGCACTGCTCGCCCTGTCAACAAAGTGATCAAGTCCGCCTCAGCCAC
AGCCCTCTCACTCCTCATTCCTTCGGAACACCACACCTGCTCCCCGTTGGCCAGCCCCATGTCCCCACATTCTCAGTCGTCCAACCCATC
ATCCCGGGACTCTTCTCCATATGGCTTCACCCTGCGGGCCATTCGCGTCTACATGGGTGACTCCGATGTCTACACCGTGCACCATATGGT
GTGGCACGTGGAGGATGGAGGTCCGGCCAGTGAGGCAGGGCTTCGTCAAGGTGACCTCATCACCCATGTCAATGGGGAACCTGTGCATGG
CCTGGTGCACACGGAGGTGGTAGAGCTGATCCTGAAGAGTGGAAACAAGGTGGCCATTTCAACAACTCCCCTGGAGAACACATCCATTAA
AGTGGGGCCAGCTCGGAAGGGCAGCTACAAGGCCAAGATGGCCCGAAGGAGCAAGAGGAGCCGCGGCAAGGATGGGCAAGAAAGCAGAAA
AAGGAGCTCCCTGTTCCGCAAGATCACCAAGCAAGCATCCCTGCTCCACACCAGCCGCAGCCTTTCTTCCCTTAACCGCTCCTTGTCATC
AGGGGAGAGTGGGCCAGGCTCTCCCACACACAGCCACAGCCTTTCCCCCCGATCTCCCACTCAAGGCTACCGGGTGACCCCCGATGCTGT
GCATTCAGAACTCTCACGGCCCAAGAGTGCGGAGCCACCCCGTTCACCACTACTCAAGAGGGTGCAGTCGGCTGAGAAACTGGCAGCAGC
ACTTGCCGCCTCTGAGAAGAAGCTAGCCACTTCTCGCAAGCACAGCCTTGACCTGCCCCACTCTGAACTAAAGAAGGAACTGCCGCCCAG
GGAAGTGAGCCCTCTGGAGGTAGTTGGAGCCAGGAGTGTGCTGTCTGGCAAGGGGGCCCTGCCAGGGAAGGGGGTGCTGCAGCCTGCTCC
CTCACGGGCCCTAGGCACCCTCCGGCAGGACCGAGCCGAACGACGGGAGTCGCTGCAGAAGCAAGAAGCCATTCGTGAGGTGGACTCCTC
AGAGGACGACACCGAGGAAGGGCCTGAGAACAGCCAGGGTGCACAGGAGCTGAGCTTGGCACCTCACCCAGAAGTGAGCCAGAGTGTGGC
CCCTAAAGGAGCAGGAGAGAGTGGGGAAGAGGATCCTTTCCCGTCCAGAGACCCTAGGAGCCTGGGCCCAATGGTCCCAAGCCTATTGAC
AGGGATCACACTGGGGCCTCCCAGAATGGAAAGTCCCAGTGGTCCCCACAGGAGGCTCGGGAGCCCACAAGCCATTGAGGAGGCTGCCAG
CTCCTCCTCAGCAGGCCCCAACCTAGGTCAGTCTGGAGCCACAGACCCCATCCCTCCTGAAGGTTGCTGGAAGGCCCAGCACCTCCACAC
CCAGGCACTAACAGCACTTTCTCCCAGCACTTCGGGACTCACCCCCACCAGCAGTTGCTCTCCTCCCAGCTCCACCTCTGGGAAGCTGAG
CATGTGGTCCTGGAAATCCCTTATTGAGGGCCCAGACAGGGCATCCCCAAGCAGAAAGGCAACCATGGCAGGTGGGCTAGCCAACCTCCA
GGATTTGGAAAACACAACTCCAGCCCAGCCTAAGAACCTGTCTCCCAGGGAGCAGGGGAAGACACAGCCACCTAGTGCCCCCAGACTGGC
CCATCCATCTTATGAGGATCCCAGCCAGGGCTGGCTATGGGAGTCTGAGTGTGCACAAGCAGTGAAAGAGGATCCAGCCCTGAGCATCAC
CCAAGTGCCTGATGCCTCAGGTGACAGAAGGCAGGACGTTCCATGCCGAGGCTGCCCCCTCACCCAGAAGTCTGAGCCCAGCCTCAGGAG

>31036_31036_4_FOS-MAST2_FOS_chr14_75747698_ENST00000535987_MAST2_chr1_46496700_ENST00000372009_length(amino acids)=756AA_BP=
MTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLTPPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPAMETRGRGTSQLAEGA
TAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMSPHSQSSNPSSRDSSPYGFTLRAIRVYMG
DSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELILKSGNKVAISTTPLENTSIKVGPARKGSYKAKMARRSKR
SRGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPTQGYRVTPDAVHSELSRPKSAEPPRSPLLK
RVQSAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSPLEVVGARSVLSGKGALPGKGVLQPAPSRALGTLRQDRAERRESLQ
KQEAIREVDSSEDDTEEGPENSQGAQELSLAPHPEVSQSVAPKGAGESGEEDPFPSRDPRSLGPMVPSLLTGITLGPPRMESPSGPHRRL
GSPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALTALSPSTSGLTPTSSCSPPSSTSGKLSMWSWKSLIEGPDRASPSRK
ATMAGGLANLQDLENTTPAQPKNLSPREQGKTQPPSAPRLAHPSYEDPSQGWLWESECAQAVKEDPALSITQVPDASGDRRQDVPCRGCP

--------------------------------------------------------------
>31036_31036_5_FOS-MAST2_FOS_chr14_75747698_ENST00000555686_MAST2_chr1_46496700_ENST00000361297_length(transcript)=4008nt_BP=1283nt
GATGCTGAAGGGATAACGGGAACGCAGCGGCAGGATGGAAGAGACAGGCACTGCGCTGCGGAATGCCTGGGAGGAAAAGGGGGAGACCTT
TCATCCAGGATGAGGGACATTTAAGATGAAATGTCCGTGGCAGGATCGTTTCTCTTCACTGCTGCATGCGGCACTGGGAACTCGCCCCAC
CTGTGTCCGGAACCTGCTCGCTCACGTCGGCTTTCCCCTTCTGTTTTGTTCTAGGACTTCTGCACGGACCTGGCCGTCTCCAGTGCCAAC
TTCATTCCCACGGTCACTGCCATCTCGACCAGTCCGGACCTGCAGTGGCTGGTGCAGCCCGCCCTCGTCTCCTCCGTGGCCCCATCGCAG
ACCAGAGCCCCTCACCCTTTCGGAGTCCCCGCCCCCTCCGCTGGGGCTTACTCCAGGGCTGGCGTTGTGAAGACCATGACAGGAGGCCGA
GCGCAGAGCATTGGCAGGAGGGGCAAGGTGGAACAGTTATCTCCAGAAGAAGAAGAGAAAAGGAGAATCCGAAGGGAAAGGAATAAGATG
GCTGCAGCCAAATGCCGCAACCGGAGGAGGGAGCTGACTGATACACTCCAAGCGTTCACCCTGCCTCTCCTCAATGACCCTGAGCCCAAG
CCCTCAGTGGAACCTGTCAAGAGCATCAGCAGCATGGAGCTGAAGACCGAGCCCTTTGATGACTTCCTGTTCCCAGCATCATCCAGGCCC
AGTGGCTCTGAGACAGCCCGCTCCGTGCCAGACATGGACCTATCTGGGTCCTTCTATGCAGCAGACTGGGAGCCTCTGCACAGTGGCTCC
CTGGGGATGGGGCCCATGGCCACAGAGCTGGAGCCCCTGTGCACTCCGGTGGTCACCTGTACTCCCAGCTGCACTGCTTACACGTCTTCC
TTCGTCTTCACCTACCCCGAGGCTGACTCCTTCCCCAGCTGTGCAGCTGCCCACCGCAAGGGCAGCAGCAGCAATGAGCCTTCCTCTGAC
TCGCTCAGCTCACCCACGCTGCTGGCCCTGTGAGGGGGCAGGGAAGGGGAGGCAGCCGGCACCCACAAGTGCCACTGCCCGAGCTGGTGC
ATTACAGAGAGGAGAAACACATCTTCCCTAGAGGGTTCCTGTAGACCTAGGGAGGACCTTATCTGTGCGTGAAACACACCAGGCTGTGGG
CCTCAAGGACTTGAAAGCATCCATGTGTGGACTCAAGTCCTTACCTCTTCCGGAGATGTAGCAAAACGCATGGAGTGTGTATTGTTCCCA
GTGACACTTCAGAGAGCTGGTAGTCTGAGTCATCCCACACAGAGAGTGACTCAAGCCCTCCAATGACAGTGCGACGCCGCTGCTCAGGCC
TCCTGGATGCGCCTCGGTTCCCGGAGGGCCCTGAGGAGGCCAGCAGCACCCTCAGGAGGCAACCACAGGAGGGTATATGGGTCCTGACAC
CCCCATCTGGAGAGGGGGTATCTGGGCCTGTCACTGAACACTCAGGGGAGCAGCGGCCAAAGCTGGATGAGGAAGCTGTTGGCCGGAGCA
GTGGTTCCAGTCCAGCTATGGAGACCCGAGGCCGTGGGACCTCACAGCTGGCTGAGGGAGCCACAGCCAAGGCCATCAGTGACCTGGCTG
TGCGTAGGGCCCGCCACCGGCTGCTCTCTGGGGACTCAACAGAGAAGCGCACTGCTCGCCCTGTCAACAAAGTGATCAAGTCCGCCTCAG
CCACAGCCCTCTCACTCCTCATTCCTTCGGAACACCACACCTGCTCCCCGTTGGCCAGCCCCATGTCCCCACATTCTCAGTCGTCCAACC
CATCATCCCGGGACTCTTCTCCAAGCAGGGACTTCTTGCCAGCCCTTGGCAGCATGAGGCCTCCCATCATCATCCACCGAGCTGGCAAGA
AGTATGGCTTCACCCTGCGGGCCATTCGCGTCTACATGGGTGACTCCGATGTCTACACCGTGCACCATATGGTGTGGCACGTGGAGGATG
GAGGTCCGGCCAGTGAGGCAGGGCTTCGTCAAGGTGACCTCATCACCCATGTCAATGGGGAACCTGTGCATGGCCTGGTGCACACGGAGG
TGGTAGAGCTGATCCTGAAGAGTGGAAACAAGGTGGCCATTTCAACAACTCCCCTGGAGAACACATCCATTAAAGTGGGGCCAGCTCGGA
AGGGCAGCTACAAGGCCAAGATGGCCCGAAGGAGCAAGAGGAGCCGCGGCAAGGATGGGCAAGAAAGCAGAAAAAGGAGCTCCCTGTTCC
GCAAGATCACCAAGCAAGCATCCCTGCTCCACACCAGCCGCAGCCTTTCTTCCCTTAACCGCTCCTTGTCATCAGGGGAGAGTGGGCCAG
GCTCTCCCACACACAGCCACAGCCTTTCCCCCCGATCTCCCACTCAAGGCTACCGGGTGACCCCCGATGCTGTGCATTCAGTGGGAGGGA
ATTCATCACAGAGCAGCTCCCCCAGCTCCAGCGTGCCCAGTTCCCCAGCCGGCTCTGGGCACACACGGCCCAGCTCCCTCCACGGTCTGG
CACCCAAGCTCCAACGCCAGTACCGCTCTCCACGGCGCAAGTCAGCAGGCAGCATCCCACTGTCACCACTGGCCCACACCCCTTCTCCCC
CACCCCCAACAGCTTCACCTCAGCGGTCCCCATCGCCCCTGTCTGGCCATGTAGCCCAGGCCTTTCCCACAAAGCTTCACTTGTCACCTC
CCCTGGGCAGGCAACTCTCACGGCCCAAGAGTGCGGAGCCACCCCGTTCACCACTACTCAAGAGGGTGCAGTCGGCTGAGAAACTGGCAG
CAGCACTTGCCGCCTCTGAGAAGAAGCTAGCCACTTCTCGCAAGCACAGCCTTGACCTGCCCCACTCTGAACTAAAGAAGGAACTGCCGC
CCAGGGAAGTGAGCCCTCTGGAGGTAGTTGGAGCCAGGAGTGTGCTGTCTGGCAAGGGGGCCCTGCCAGGGAAGGGGGTGCTGCAGCCTG
CTCCCTCACGGGCCCTAGGCACCCTCCGGCAGGACCGAGCCGAACGACGGGAGTCGCTGCAGAAGCAAGAAGCCATTCGTGAGGTGGACT
CCTCAGAGGACGACACCGAGGAAGGGCCTGAGAACAGCCAGGGTGCACAGGAGCTGAGCTTGGCACCTCACCCAGAAGTGAGCCAGAGTG
TGGCCCCTAAAGGAGCAGGAGAGAGTGGGGAAGAGGATCCTTTCCCGTCCAGAGACCCTAGGAGCCTGGGCCCAATGGTCCCAAGCCTAT
TGACAGGGATCACACTGGGGCCTCCCAGAATGGAAAGTCCCAGTGGTCCCCACAGGAGGCTCGGGAGCCCACAAGCCATTGAGGAGGCTG
CCAGCTCCTCCTCAGCAGGCCCCAACCTAGGTCAGTCTGGAGCCACAGACCCCATCCCTCCTGAAGGTTGCTGGAAGGCCCAGCACCTCC
ACACCCAGGCACTAACAGCACTTTCTCCCAGCACTTCGGGACTCACCCCCACCAGCAGTTGCTCTCCTCCCAGCTCCACCTCTGGGAAGC
TGAGCATGTGGTCCTGGAAATCCCTTATTGAGGGCCCAGACAGGGCATCCCCAAGCAGAAAGGCAACCATGGCAGGTGGGCTAGCCAACC
TCCAGGATTTGGAAAACACAACTCCAGCCCAGCCTAAGAACCTGTCTCCCAGGGAGCAGGGGAAGACACAGCCACCTAGTGCCCCCAGAC
TGGCCCATCCATCTTATGAGGATCCCAGCCAGGGCTGGCTATGGGAGTCTGAGTGTGCACAAGCAGTGAAAGAGGATCCAGCCCTGAGCA
TCACCCAAGTGCCTGATGCCTCAGGTGACAGAAGGCAGGACGTTCCATGCCGAGGCTGCCCCCTCACCCAGAAGTCTGAGCCCAGCCTCA
GGAGGGGCCAAGAACCAGGGGGCCATCAAAAGCATCGGGATTTGGCATTGGTTCCAGATGAGCTTTTAAAGCAAACATAGCAGTTGTTTG

>31036_31036_5_FOS-MAST2_FOS_chr14_75747698_ENST00000555686_MAST2_chr1_46496700_ENST00000361297_length(amino acids)=875AA_BP=
MTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLTPPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPAMETRGRGTSQLAEGA
TAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMSPHSQSSNPSSRDSSPSRDFLPALGSMRP
PIIIHRAGKKYGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELILKSGNKVAISTTPLEN
TSIKVGPARKGSYKAKMARRSKRSRGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPTQGYRVT
PDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPPPTASPQRSPSPLSGHVAQA
FPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSPLEVVGARSVLSGKGA
LPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTEEGPENSQGAQELSLAPHPEVSQSVAPKGAGESGEEDPFPSRDPR
SLGPMVPSLLTGITLGPPRMESPSGPHRRLGSPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALTALSPSTSGLTPTSSC
SPPSSTSGKLSMWSWKSLIEGPDRASPSRKATMAGGLANLQDLENTTPAQPKNLSPREQGKTQPPSAPRLAHPSYEDPSQGWLWESECAQ

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>31036_31036_6_FOS-MAST2_FOS_chr14_75747698_ENST00000555686_MAST2_chr1_46496700_ENST00000372009_length(transcript)=3590nt_BP=1283nt
GATGCTGAAGGGATAACGGGAACGCAGCGGCAGGATGGAAGAGACAGGCACTGCGCTGCGGAATGCCTGGGAGGAAAAGGGGGAGACCTT
TCATCCAGGATGAGGGACATTTAAGATGAAATGTCCGTGGCAGGATCGTTTCTCTTCACTGCTGCATGCGGCACTGGGAACTCGCCCCAC
CTGTGTCCGGAACCTGCTCGCTCACGTCGGCTTTCCCCTTCTGTTTTGTTCTAGGACTTCTGCACGGACCTGGCCGTCTCCAGTGCCAAC
TTCATTCCCACGGTCACTGCCATCTCGACCAGTCCGGACCTGCAGTGGCTGGTGCAGCCCGCCCTCGTCTCCTCCGTGGCCCCATCGCAG
ACCAGAGCCCCTCACCCTTTCGGAGTCCCCGCCCCCTCCGCTGGGGCTTACTCCAGGGCTGGCGTTGTGAAGACCATGACAGGAGGCCGA
GCGCAGAGCATTGGCAGGAGGGGCAAGGTGGAACAGTTATCTCCAGAAGAAGAAGAGAAAAGGAGAATCCGAAGGGAAAGGAATAAGATG
GCTGCAGCCAAATGCCGCAACCGGAGGAGGGAGCTGACTGATACACTCCAAGCGTTCACCCTGCCTCTCCTCAATGACCCTGAGCCCAAG
CCCTCAGTGGAACCTGTCAAGAGCATCAGCAGCATGGAGCTGAAGACCGAGCCCTTTGATGACTTCCTGTTCCCAGCATCATCCAGGCCC
AGTGGCTCTGAGACAGCCCGCTCCGTGCCAGACATGGACCTATCTGGGTCCTTCTATGCAGCAGACTGGGAGCCTCTGCACAGTGGCTCC
CTGGGGATGGGGCCCATGGCCACAGAGCTGGAGCCCCTGTGCACTCCGGTGGTCACCTGTACTCCCAGCTGCACTGCTTACACGTCTTCC
TTCGTCTTCACCTACCCCGAGGCTGACTCCTTCCCCAGCTGTGCAGCTGCCCACCGCAAGGGCAGCAGCAGCAATGAGCCTTCCTCTGAC
TCGCTCAGCTCACCCACGCTGCTGGCCCTGTGAGGGGGCAGGGAAGGGGAGGCAGCCGGCACCCACAAGTGCCACTGCCCGAGCTGGTGC
ATTACAGAGAGGAGAAACACATCTTCCCTAGAGGGTTCCTGTAGACCTAGGGAGGACCTTATCTGTGCGTGAAACACACCAGGCTGTGGG
CCTCAAGGACTTGAAAGCATCCATGTGTGGACTCAAGTCCTTACCTCTTCCGGAGATGTAGCAAAACGCATGGAGTGTGTATTGTTCCCA
GTGACACTTCAGAGAGCTGGTAGTCTGAGTCATCCCACACAGAGAGTGACTCAAGCCCTCCAATGACAGTGCGACGCCGCTGCTCAGGCC
TCCTGGATGCGCCTCGGTTCCCGGAGGGCCCTGAGGAGGCCAGCAGCACCCTCAGGAGGCAACCACAGGAGGGTATATGGGTCCTGACAC
CCCCATCTGGAGAGGGGGTATCTGGGCCTGTCACTGAACACTCAGGGGAGCAGCGGCCAAAGCTGGATGAGGAAGCTGTTGGCCGGAGCA
GTGGTTCCAGTCCAGCTATGGAGACCCGAGGCCGTGGGACCTCACAGCTGGCTGAGGGAGCCACAGCCAAGGCCATCAGTGACCTGGCTG
TGCGTAGGGCCCGCCACCGGCTGCTCTCTGGGGACTCAACAGAGAAGCGCACTGCTCGCCCTGTCAACAAAGTGATCAAGTCCGCCTCAG
CCACAGCCCTCTCACTCCTCATTCCTTCGGAACACCACACCTGCTCCCCGTTGGCCAGCCCCATGTCCCCACATTCTCAGTCGTCCAACC
CATCATCCCGGGACTCTTCTCCATATGGCTTCACCCTGCGGGCCATTCGCGTCTACATGGGTGACTCCGATGTCTACACCGTGCACCATA
TGGTGTGGCACGTGGAGGATGGAGGTCCGGCCAGTGAGGCAGGGCTTCGTCAAGGTGACCTCATCACCCATGTCAATGGGGAACCTGTGC
ATGGCCTGGTGCACACGGAGGTGGTAGAGCTGATCCTGAAGAGTGGAAACAAGGTGGCCATTTCAACAACTCCCCTGGAGAACACATCCA
TTAAAGTGGGGCCAGCTCGGAAGGGCAGCTACAAGGCCAAGATGGCCCGAAGGAGCAAGAGGAGCCGCGGCAAGGATGGGCAAGAAAGCA
GAAAAAGGAGCTCCCTGTTCCGCAAGATCACCAAGCAAGCATCCCTGCTCCACACCAGCCGCAGCCTTTCTTCCCTTAACCGCTCCTTGT
CATCAGGGGAGAGTGGGCCAGGCTCTCCCACACACAGCCACAGCCTTTCCCCCCGATCTCCCACTCAAGGCTACCGGGTGACCCCCGATG
CTGTGCATTCAGAACTCTCACGGCCCAAGAGTGCGGAGCCACCCCGTTCACCACTACTCAAGAGGGTGCAGTCGGCTGAGAAACTGGCAG
CAGCACTTGCCGCCTCTGAGAAGAAGCTAGCCACTTCTCGCAAGCACAGCCTTGACCTGCCCCACTCTGAACTAAAGAAGGAACTGCCGC
CCAGGGAAGTGAGCCCTCTGGAGGTAGTTGGAGCCAGGAGTGTGCTGTCTGGCAAGGGGGCCCTGCCAGGGAAGGGGGTGCTGCAGCCTG
CTCCCTCACGGGCCCTAGGCACCCTCCGGCAGGACCGAGCCGAACGACGGGAGTCGCTGCAGAAGCAAGAAGCCATTCGTGAGGTGGACT
CCTCAGAGGACGACACCGAGGAAGGGCCTGAGAACAGCCAGGGTGCACAGGAGCTGAGCTTGGCACCTCACCCAGAAGTGAGCCAGAGTG
TGGCCCCTAAAGGAGCAGGAGAGAGTGGGGAAGAGGATCCTTTCCCGTCCAGAGACCCTAGGAGCCTGGGCCCAATGGTCCCAAGCCTAT
TGACAGGGATCACACTGGGGCCTCCCAGAATGGAAAGTCCCAGTGGTCCCCACAGGAGGCTCGGGAGCCCACAAGCCATTGAGGAGGCTG
CCAGCTCCTCCTCAGCAGGCCCCAACCTAGGTCAGTCTGGAGCCACAGACCCCATCCCTCCTGAAGGTTGCTGGAAGGCCCAGCACCTCC
ACACCCAGGCACTAACAGCACTTTCTCCCAGCACTTCGGGACTCACCCCCACCAGCAGTTGCTCTCCTCCCAGCTCCACCTCTGGGAAGC
TGAGCATGTGGTCCTGGAAATCCCTTATTGAGGGCCCAGACAGGGCATCCCCAAGCAGAAAGGCAACCATGGCAGGTGGGCTAGCCAACC
TCCAGGATTTGGAAAACACAACTCCAGCCCAGCCTAAGAACCTGTCTCCCAGGGAGCAGGGGAAGACACAGCCACCTAGTGCCCCCAGAC
TGGCCCATCCATCTTATGAGGATCCCAGCCAGGGCTGGCTATGGGAGTCTGAGTGTGCACAAGCAGTGAAAGAGGATCCAGCCCTGAGCA
TCACCCAAGTGCCTGATGCCTCAGGTGACAGAAGGCAGGACGTTCCATGCCGAGGCTGCCCCCTCACCCAGAAGTCTGAGCCCAGCCTCA

>31036_31036_6_FOS-MAST2_FOS_chr14_75747698_ENST00000555686_MAST2_chr1_46496700_ENST00000372009_length(amino acids)=756AA_BP=
MTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLTPPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPAMETRGRGTSQLAEGA
TAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMSPHSQSSNPSSRDSSPYGFTLRAIRVYMG
DSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELILKSGNKVAISTTPLENTSIKVGPARKGSYKAKMARRSKR
SRGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPTQGYRVTPDAVHSELSRPKSAEPPRSPLLK
RVQSAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSPLEVVGARSVLSGKGALPGKGVLQPAPSRALGTLRQDRAERRESLQ
KQEAIREVDSSEDDTEEGPENSQGAQELSLAPHPEVSQSVAPKGAGESGEEDPFPSRDPRSLGPMVPSLLTGITLGPPRMESPSGPHRRL
GSPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALTALSPSTSGLTPTSSCSPPSSTSGKLSMWSWKSLIEGPDRASPSRK
ATMAGGLANLQDLENTTPAQPKNLSPREQGKTQPPSAPRLAHPSYEDPSQGWLWESECAQAVKEDPALSITQVPDASGDRRQDVPCRGCP

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Fusion Gene PPI Analysis for FOS-MAST2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FOS-MAST2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FOS-MAST2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource