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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AHR-CDK14 (FusionGDB2 ID:3134)

Fusion Gene Summary for AHR-CDK14

check button Fusion gene summary
Fusion gene informationFusion gene name: AHR-CDK14
Fusion gene ID: 3134
HgeneTgene
Gene symbol

AHR

CDK14

Gene ID

196

5218

Gene namearyl hydrocarbon receptorcyclin dependent kinase 14
SynonymsRP85|bHLHe76PFTAIRE1|PFTK1
Cytomap

7p21.1

7q21.13

Type of geneprotein-codingprotein-coding
Descriptionaryl hydrocarbon receptorAH-receptorah receptoraromatic hydrocarbon receptorclass E basic helix-loop-helix protein 76cyclin-dependent kinase 14PFTAIRE protein kinase 1cell division protein kinase 14serine/threonine-protein kinase PFTAIRE-1
Modification date2020032220200313
UniProtAcc

P35869

O94921

Ensembl transtripts involved in fusion geneENST00000242057, ENST00000492120, 
ENST00000496279, ENST00000265741, 
ENST00000380050, ENST00000406263, 
ENST00000436577, 
Fusion gene scores* DoF score6 X 5 X 5=15022 X 24 X 12=6336
# samples 832
** MAII scorelog2(8/150*10)=-0.906890595608519
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(32/6336*10)=-4.30742852519225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AHR [Title/Abstract] AND CDK14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAHR(17338953)-CDK14(90741857), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAHR

GO:0006355

regulation of transcription, DNA-templated

10395741

HgeneAHR

GO:0006357

regulation of transcription by RNA polymerase II

15681594

HgeneAHR

GO:0006366

transcription by RNA polymerase II

10395741

HgeneAHR

GO:0009410

response to xenobiotic stimulus

7961644

HgeneAHR

GO:0009636

response to toxic substance

7961644

HgeneAHR

GO:0010468

regulation of gene expression

15681594

HgeneAHR

GO:0019933

cAMP-mediated signaling

17329248

HgeneAHR

GO:0030888

regulation of B cell proliferation

15681594

HgeneAHR

GO:0071320

cellular response to cAMP

17329248

HgeneAHR

GO:1904322

cellular response to forskolin

17329248

HgeneAHR

GO:1904613

cellular response to 2,3,7,8-tetrachlorodibenzodioxine

17329248

TgeneCDK14

GO:0000086

G2/M transition of mitotic cell cycle

20059949

TgeneCDK14

GO:0060828

regulation of canonical Wnt signaling pathway

20059949


check buttonFusion gene breakpoints across AHR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CDK14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AN-A0FY-01AAHRchr7

17338953

-CDK14chr7

90741857

+
ChimerDB4BRCATCGA-AN-A0FY-01AAHRchr7

17338953

+CDK14chr7

90741857

+


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Fusion Gene ORF analysis for AHR-CDK14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000242057ENST00000496279AHRchr7

17338953

+CDK14chr7

90741857

+
In-frameENST00000242057ENST00000265741AHRchr7

17338953

+CDK14chr7

90741857

+
In-frameENST00000242057ENST00000380050AHRchr7

17338953

+CDK14chr7

90741857

+
In-frameENST00000242057ENST00000406263AHRchr7

17338953

+CDK14chr7

90741857

+
In-frameENST00000242057ENST00000436577AHRchr7

17338953

+CDK14chr7

90741857

+
intron-3CDSENST00000492120ENST00000265741AHRchr7

17338953

+CDK14chr7

90741857

+
intron-3CDSENST00000492120ENST00000380050AHRchr7

17338953

+CDK14chr7

90741857

+
intron-3CDSENST00000492120ENST00000406263AHRchr7

17338953

+CDK14chr7

90741857

+
intron-3CDSENST00000492120ENST00000436577AHRchr7

17338953

+CDK14chr7

90741857

+
intron-intronENST00000492120ENST00000496279AHRchr7

17338953

+CDK14chr7

90741857

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000242057AHRchr717338953+ENST00000380050CDK14chr790741857+44187087261242
ENST00000242057AHRchr717338953+ENST00000265741CDK14chr790741857+44177087261242
ENST00000242057AHRchr717338953+ENST00000406263CDK14chr790741857+4413708502963153
ENST00000242057AHRchr717338953+ENST00000436577CDK14chr790741857+11907087261242

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000242057ENST00000380050AHRchr717338953+CDK14chr790741857+0.0468012430.9531987
ENST00000242057ENST00000265741AHRchr717338953+CDK14chr790741857+0.0673946740.9326054
ENST00000242057ENST00000406263AHRchr717338953+CDK14chr790741857+0.075158990.92484105
ENST00000242057ENST00000436577AHRchr717338953+CDK14chr790741857+0.067595880.93240416

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Fusion Genomic Features for AHR-CDK14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AHRchr717338953+CDK14chr790741856+6.10E-091
AHRchr717338953+CDK14chr790741856+6.10E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for AHR-CDK14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:17338953/chr7:90741857)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AHR

P35869

CDK14

O94921

FUNCTION: Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer (PubMed:30373764, PubMed:23275542, PubMed:7961644, PubMed:32818467). Upon ligand binding, translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE) (PubMed:30373764, PubMed:23275542, PubMed:7961644). Regulates a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation (PubMed:12213388). Xenobiotics can act as ligands: upon xenobiotic-binding, activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene) (PubMed:7961644). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons (PubMed:7961644). Next to xenobiotics, natural ligands derived from plants, microbiota, and endogenous metabolism are potent AHR agonists (PubMed:18076143). Tryptophan (Trp) derivatives constitute an important class of endogenous AHR ligands (PubMed:32866000, PubMed:32818467). Acts as a negative regulator of anti-tumor immunity: indoles and kynurenic acid generated by Trp catabolism act as ligand and activate AHR, thereby promoting AHR-driven cancer cell motility and suppressing adaptive immunity (PubMed:32818467). Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1 (PubMed:28602820). Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1 (PubMed:28602820). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28602820). {ECO:0000269|PubMed:23275542, ECO:0000269|PubMed:28602820, ECO:0000269|PubMed:30373764, ECO:0000269|PubMed:32818467, ECO:0000269|PubMed:32866000, ECO:0000269|PubMed:7961644, ECO:0000303|PubMed:12213388, ECO:0000303|PubMed:18076143}.FUNCTION: Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. {ECO:0000269|PubMed:16461467, ECO:0000269|PubMed:17517622, ECO:0000269|PubMed:19524571, ECO:0000269|PubMed:20059949}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+111600_64021849.0Compositional biasNote=Gln-rich
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+111111_18121849.0DomainPAS 1
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+111275_34221849.0DomainPAS 2
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+11127_8021849.0DomainbHLH
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+111348_38621849.0DomainNote=PAC
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+111118_12621849.0RegionRequired for maintaining the overall integrity of the AHR:ARNT heterodimer and its transcriptional activity
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+111266_26821849.0RegionRequired for maintaining the overall integrity of the AHR:ARNT heterodimer and its transcriptional activity
HgeneAHRchr7:17338953chr7:90741857ENST00000242057+11138_6621849.0RegionDNA-binding
TgeneCDK14chr7:17338953chr7:90741857ENST000002657411014135_4193661522.6666666666667DomainProtein kinase
TgeneCDK14chr7:17338953chr7:90741857ENST000003800501115135_4193841538.0DomainProtein kinase
TgeneCDK14chr7:17338953chr7:90741857ENST000004062631014135_4193381422.0DomainProtein kinase
TgeneCDK14chr7:17338953chr7:90741857ENST000002657411014141_1493661522.6666666666667Nucleotide bindingATP
TgeneCDK14chr7:17338953chr7:90741857ENST000003800501115141_1493841538.0Nucleotide bindingATP
TgeneCDK14chr7:17338953chr7:90741857ENST000004062631014141_1493381422.0Nucleotide bindingATP


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Fusion Gene Sequence for AHR-CDK14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>3134_3134_1_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000265741_length(transcript)=4417nt_BP=708nt
ATTCAGCCGGTGCGCGCGGCGGCGGGAGGCAGTGGCTGGGGAGTCCCGTCGACGCTCTGTTCCGAGAGCGTGCCCCGGACCGCCAGCTCA
GAACAGGGGCAGCCGTGTAGCCGAACGGAAGCTGGGAGCAGCCGGGACTGGTGGCCCGCGCCCGAGCTCCGCAGGCGGGAAGCACCCTGG
ATTTAGGAAGTCCCGGGAGCAGCGCGGCGGCACCTCCCTCACCCAAGGGGCCGCGGCGACGGTCACGGGGCGCGGCGCCACCGTGAGCGA
CCCAGGCCAGGATTCTAAATAGACGGCCCAGGCTCCTCCTCCGCCCGGGCCGCCTCACCTGCGGGCATTGCCGCGCCGCCTCCGCCGGTG
TAGACGGCACCTGCGCCGCCTTGCTCGCGGGTCTCCGCCCCTCGCCCACCCTCACTGCGCCAGGCCCAGGCAGCTCACCTGTACTGGCGC
GGGCTGCGGAAGCCTGCGTGAGCCGAGGCGTTGAGGCGCGGCGCCCACGCCACTGTCCCGAGAGGACGCAGGTGGAGCGGGCGCGGCTTC
GCGGAACCCGGCGCCGGCCGCCGCAGTGGTCCCAGCCTACACCGGGTTCCGGGGACCCGGCCGCCAGTGCCCGGGGAGTAGCCGCCGCCG
TCGGCTGGGCACCATGAACAGCAGCAGCGCCAACATCACCTACGCCAGTCGCAAGCGGCGGAAGCCGGTGCAGAAAACGCTCAGCTATGT
GAACCATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACGAGTATTT
TAGTGACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAGCTGGAGA
AAGCATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAGAGCACAC
AGGATTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTTTTCTTTC
GCTCCCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCACGCATTTG
GATACCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTGTTTGATT
TTGTTTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAACACATTT
GGTGTTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTGCACATTT
TGCAACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCCACCTGTT
GCTTACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTGCTTAGCA
TTTTCAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGGATAAATT
GCTTACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGTTACACTT
TGTATTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTTGAAAGCA
GTCTTGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAAAAAAATA
CATTTTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAATGCAGGTT
TTAGAAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTGGAGGATG
AAGGCGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCCGGCTCCC
AGTGGGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACCTAGCTCC
TCTACACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGTGAGTGCT
TGAAATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGGGTAAAGC
TTTTCTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAGTATGGAT
GGTTATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACTGATTGGT
TTTAAAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATTCCAACCC
ACTGGAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACATGCAATT
AAAAATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCAAGAGCAA
CTGATGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGCTATTAGA
GTTATATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTACAGAGACA
TGCCTCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTCTGTCTCT
TTCTTTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTGCTTCTTT
TCTCTTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGCACTGGAA
TGTTTTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCACTGCACA
CACAGTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACATAGGATG
TGAAAAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGAAGCGATT
TCTACCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCTCAGTGTG
TATATGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTTTGTTATA
TAAGAGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATAACTTCCA
TCTCCCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAAAATCAAT
AAAATAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTGGGAGTGG
ATTTTTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCTAAGAAAT
GTGGTAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTTACCAGTT
GTAATTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTATAGCAGAA

>3134_3134_1_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000265741_length(amino acids)=242AA_BP=
MVHIAERFLHRLPPLATGVGDVGAAAVHGAQPTAAATPRALAAGSPEPGVGWDHCGGRRRVPRSRARSTCVLSGQWRGRRASTPRLTQAS
AARASTGELPGPGAVRVGEGRRPASKAAQVPSTPAEAARQCPQVRRPGRRRSLGRLFRILAWVAHGGAAPRDRRRGPLGEGGAAALLPGL

--------------------------------------------------------------
>3134_3134_2_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000380050_length(transcript)=4418nt_BP=708nt
ATTCAGCCGGTGCGCGCGGCGGCGGGAGGCAGTGGCTGGGGAGTCCCGTCGACGCTCTGTTCCGAGAGCGTGCCCCGGACCGCCAGCTCA
GAACAGGGGCAGCCGTGTAGCCGAACGGAAGCTGGGAGCAGCCGGGACTGGTGGCCCGCGCCCGAGCTCCGCAGGCGGGAAGCACCCTGG
ATTTAGGAAGTCCCGGGAGCAGCGCGGCGGCACCTCCCTCACCCAAGGGGCCGCGGCGACGGTCACGGGGCGCGGCGCCACCGTGAGCGA
CCCAGGCCAGGATTCTAAATAGACGGCCCAGGCTCCTCCTCCGCCCGGGCCGCCTCACCTGCGGGCATTGCCGCGCCGCCTCCGCCGGTG
TAGACGGCACCTGCGCCGCCTTGCTCGCGGGTCTCCGCCCCTCGCCCACCCTCACTGCGCCAGGCCCAGGCAGCTCACCTGTACTGGCGC
GGGCTGCGGAAGCCTGCGTGAGCCGAGGCGTTGAGGCGCGGCGCCCACGCCACTGTCCCGAGAGGACGCAGGTGGAGCGGGCGCGGCTTC
GCGGAACCCGGCGCCGGCCGCCGCAGTGGTCCCAGCCTACACCGGGTTCCGGGGACCCGGCCGCCAGTGCCCGGGGAGTAGCCGCCGCCG
TCGGCTGGGCACCATGAACAGCAGCAGCGCCAACATCACCTACGCCAGTCGCAAGCGGCGGAAGCCGGTGCAGAAAACGCTCAGCTATGT
GAACCATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACGAGTATTT
TAGTGACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAGCTGGAGA
AAGCATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAGAGCACAC
AGGATTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTTTTCTTTC
GCTCCCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCACGCATTTG
GATACCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTGTTTGATT
TTGTTTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAACACATTT
GGTGTTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTGCACATTT
TGCAACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCCACCTGTT
GCTTACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTGCTTAGCA
TTTTCAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGGATAAATT
GCTTACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGTTACACTT
TGTATTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTTGAAAGCA
GTCTTGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAAAAAAATA
CATTTTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAATGCAGGTT
TTAGAAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTGGAGGATG
AAGGCGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCCGGCTCCC
AGTGGGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACCTAGCTCC
TCTACACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGTGAGTGCT
TGAAATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGGGTAAAGC
TTTTCTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAGTATGGAT
GGTTATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACTGATTGGT
TTTAAAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATTCCAACCC
ACTGGAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACATGCAATT
AAAAATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCAAGAGCAA
CTGATGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGCTATTAGA
GTTATATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTACAGAGACA
TGCCTCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTCTGTCTCT
TTCTTTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTGCTTCTTT
TCTCTTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGCACTGGAA
TGTTTTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCACTGCACA
CACAGTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACATAGGATG
TGAAAAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGAAGCGATT
TCTACCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCTCAGTGTG
TATATGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTTTGTTATA
TAAGAGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATAACTTCCA
TCTCCCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAAAATCAAT
AAAATAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTGGGAGTGG
ATTTTTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCTAAGAAAT
GTGGTAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTTACCAGTT
GTAATTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTATAGCAGAA

>3134_3134_2_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000380050_length(amino acids)=242AA_BP=
MVHIAERFLHRLPPLATGVGDVGAAAVHGAQPTAAATPRALAAGSPEPGVGWDHCGGRRRVPRSRARSTCVLSGQWRGRRASTPRLTQAS
AARASTGELPGPGAVRVGEGRRPASKAAQVPSTPAEAARQCPQVRRPGRRRSLGRLFRILAWVAHGGAAPRDRRRGPLGEGGAAALLPGL

--------------------------------------------------------------
>3134_3134_3_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000406263_length(transcript)=4413nt_BP=708nt
ATTCAGCCGGTGCGCGCGGCGGCGGGAGGCAGTGGCTGGGGAGTCCCGTCGACGCTCTGTTCCGAGAGCGTGCCCCGGACCGCCAGCTCA
GAACAGGGGCAGCCGTGTAGCCGAACGGAAGCTGGGAGCAGCCGGGACTGGTGGCCCGCGCCCGAGCTCCGCAGGCGGGAAGCACCCTGG
ATTTAGGAAGTCCCGGGAGCAGCGCGGCGGCACCTCCCTCACCCAAGGGGCCGCGGCGACGGTCACGGGGCGCGGCGCCACCGTGAGCGA
CCCAGGCCAGGATTCTAAATAGACGGCCCAGGCTCCTCCTCCGCCCGGGCCGCCTCACCTGCGGGCATTGCCGCGCCGCCTCCGCCGGTG
TAGACGGCACCTGCGCCGCCTTGCTCGCGGGTCTCCGCCCCTCGCCCACCCTCACTGCGCCAGGCCCAGGCAGCTCACCTGTACTGGCGC
GGGCTGCGGAAGCCTGCGTGAGCCGAGGCGTTGAGGCGCGGCGCCCACGCCACTGTCCCGAGAGGACGCAGGTGGAGCGGGCGCGGCTTC
GCGGAACCCGGCGCCGGCCGCCGCAGTGGTCCCAGCCTACACCGGGTTCCGGGGACCCGGCCGCCAGTGCCCGGGGAGTAGCCGCCGCCG
TCGGCTGGGCACCATGAACAGCAGCAGCGCCAACATCACCTACGCCAGTCGCAAGCGGCGGAAGCCGGTGCAGAAAACGCTCAGCTATGT
GAACCATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACGAGTATTT
TAGTGACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAGCTGGAGA
AAGCATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAGAGCACAC
AGGATTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTTTTCTTTC
GCTCCCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCACGCATTTG
GATACCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTGTTTGATT
TTGTTTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAACACATTT
GGTGTTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTGCACATTT
TGCAACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCCACCTGTT
GCTTACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTGCTTAGCA
TTTTCAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGGATAAATT
GCTTACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGTTACACTT
TGTATTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTTGAAAGCA
GTCTTGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAAAAAAATA
CATTTTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAATGCAGGTT
TTAGAAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTGGAGGATG
AAGGCGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCCGGCTCCC
AGTGGGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACCTAGCTCC
TCTACACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGTGAGTGCT
TGAAATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGGGTAAAGC
TTTTCTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAGTATGGAT
GGTTATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACTGATTGGT
TTTAAAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATTCCAACCC
ACTGGAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACATGCAATT
AAAAATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCAAGAGCAA
CTGATGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGCTATTAGA
GTTATATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTACAGAGACA
TGCCTCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTCTGTCTCT
TTCTTTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTGCTTCTTT
TCTCTTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGCACTGGAA
TGTTTTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCACTGCACA
CACAGTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACATAGGATG
TGAAAAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGAAGCGATT
TCTACCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCTCAGTGTG
TATATGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTTTGTTATA
TAAGAGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATAACTTCCA
TCTCCCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAAAATCAAT
AAAATAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTGGGAGTGG
ATTTTTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCTAAGAAAT
GTGGTAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTTACCAGTT
GTAATTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTATAGCAGAA

>3134_3134_3_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000406263_length(amino acids)=153AA_BP=69
MSREDAGGAGAASRNPAPAAAVVPAYTGFRGPGRQCPGSSRRRRLGTMNSSSANITYASRKRRKPVQKTLSYVNHAEDLASKLLQCSPKN

--------------------------------------------------------------
>3134_3134_4_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000436577_length(transcript)=1190nt_BP=708nt
ATTCAGCCGGTGCGCGCGGCGGCGGGAGGCAGTGGCTGGGGAGTCCCGTCGACGCTCTGTTCCGAGAGCGTGCCCCGGACCGCCAGCTCA
GAACAGGGGCAGCCGTGTAGCCGAACGGAAGCTGGGAGCAGCCGGGACTGGTGGCCCGCGCCCGAGCTCCGCAGGCGGGAAGCACCCTGG
ATTTAGGAAGTCCCGGGAGCAGCGCGGCGGCACCTCCCTCACCCAAGGGGCCGCGGCGACGGTCACGGGGCGCGGCGCCACCGTGAGCGA
CCCAGGCCAGGATTCTAAATAGACGGCCCAGGCTCCTCCTCCGCCCGGGCCGCCTCACCTGCGGGCATTGCCGCGCCGCCTCCGCCGGTG
TAGACGGCACCTGCGCCGCCTTGCTCGCGGGTCTCCGCCCCTCGCCCACCCTCACTGCGCCAGGCCCAGGCAGCTCACCTGTACTGGCGC
GGGCTGCGGAAGCCTGCGTGAGCCGAGGCGTTGAGGCGCGGCGCCCACGCCACTGTCCCGAGAGGACGCAGGTGGAGCGGGCGCGGCTTC
GCGGAACCCGGCGCCGGCCGCCGCAGTGGTCCCAGCCTACACCGGGTTCCGGGGACCCGGCCGCCAGTGCCCGGGGAGTAGCCGCCGCCG
TCGGCTGGGCACCATGAACAGCAGCAGCGCCAACATCACCTACGCCAGTCGCAAGCGGCGGAAGCCGGTGCAGAAAACGCTCAGCTATGT
GAACCATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACGAGTATTT
TAGTGACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAGCTGGAGA
AAGCATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAGAGCACAC
AGGATTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTTTTCTTTC
GCTCCCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCACGCATTTG

>3134_3134_4_AHR-CDK14_AHR_chr7_17338953_ENST00000242057_CDK14_chr7_90741857_ENST00000436577_length(amino acids)=242AA_BP=
MVHIAERFLHRLPPLATGVGDVGAAAVHGAQPTAAATPRALAAGSPEPGVGWDHCGGRRRVPRSRARSTCVLSGQWRGRRASTPRLTQAS
AARASTGELPGPGAVRVGEGRRPASKAAQVPSTPAEAARQCPQVRRPGRRRSLGRLFRILAWVAHGGAAPRDRRRGPLGEGGAAALLPGL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AHR-CDK14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AHR-CDK14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AHR-CDK14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource