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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FRMD8-DDX39B (FusionGDB2 ID:31378)

Fusion Gene Summary for FRMD8-DDX39B

check button Fusion gene summary
Fusion gene informationFusion gene name: FRMD8-DDX39B
Fusion gene ID: 31378
HgeneTgene
Gene symbol

FRMD8

DDX39B

Gene ID

83786

7919

Gene nameFERM domain containing 8DExD-box helicase 39B
SynonymsFKSG44|iTAPBAT1|D6S81E|UAP56
Cytomap

11q13.1

6p21.33

Type of geneprotein-codingprotein-coding
DescriptionFERM domain-containing protein 8band4.1 inhibitor LRP interactorbiliiRhom Tail-Associated Proteinspliceosome RNA helicase DDX39B56 kDa U2AF65-associated proteinATP-dependent RNA helicase p47DEAD (Asp-Glu-Ala-Asp) box polypeptide 39BDEAD-box helicase 39BHLA-B-associated transcript 1 proteinnuclear RNA helicase (DEAD family)spliceosome RNA helic
Modification date2020031320200313
UniProtAcc

Q9BZ67

Q13838

Ensembl transtripts involved in fusion geneENST00000317568, ENST00000355991, 
ENST00000416776, ENST00000531296, 
ENST00000383508, ENST00000400293, 
ENST00000400295, ENST00000400296, 
ENST00000412106, ENST00000412330, 
ENST00000413678, ENST00000414440, 
ENST00000415382, ENST00000415689, 
ENST00000416863, ENST00000430703, 
ENST00000430784, ENST00000431360, 
ENST00000438578, ENST00000441425, 
ENST00000445218, ENST00000446341, 
ENST00000448296, ENST00000449074, 
ENST00000450987, ENST00000453105, 
ENST00000453138, ENST00000453488, 
ENST00000456476, ENST00000456666, 
ENST00000462421, ENST00000463430, 
ENST00000468089, ENST00000470514, 
ENST00000483957, ENST00000489325, 
ENST00000495391, ENST00000546633, 
ENST00000546637, ENST00000547039, 
ENST00000547489, ENST00000548331, 
ENST00000548340, ENST00000548614, 
ENST00000549374, ENST00000550217, 
ENST00000550435, ENST00000551031, 
ENST00000552288, ENST00000552820, 
ENST00000376177, ENST00000396172, 
ENST00000417556, ENST00000458640, 
Fusion gene scores* DoF score11 X 8 X 8=70410 X 4 X 6=240
# samples 1611
** MAII scorelog2(16/704*10)=-2.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/240*10)=-1.12553088208386
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FRMD8 [Title/Abstract] AND DDX39B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFRMD8(65172539)-DDX39B(31503262), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFRMD8

GO:1904469

positive regulation of tumor necrosis factor secretion

29897333

TgeneDDX39B

GO:0000245

spliceosomal complex assembly

18593880

TgeneDDX39B

GO:0006406

mRNA export from nucleus

17190602

TgeneDDX39B

GO:0008380

RNA splicing

18593880

TgeneDDX39B

GO:0010501

RNA secondary structure unwinding

18593880

TgeneDDX39B

GO:0046784

viral mRNA export from host cell nucleus

18974867


check buttonFusion gene breakpoints across FRMD8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DDX39B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-6822-01AFRMD8chr11

65172539

+DDX39Bchr6

31503262

-


Top

Fusion Gene ORF analysis for FRMD8-DDX39B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000317568ENST00000383508FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000400293FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000400295FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000400296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000412106FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000412330FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000413678FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000414440FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000415382FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000415689FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000416863FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000430703FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000430784FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000431360FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000438578FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000441425FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000445218FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000446341FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000448296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000449074FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000450987FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000453105FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000453138FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000453488FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000456476FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000456666FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000462421FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000463430FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000468089FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000470514FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000483957FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000489325FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000495391FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000546633FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000546637FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000547039FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000547489FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000548331FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000548340FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000548614FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000549374FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000550217FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000550435FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000551031FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000552288FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000317568ENST00000552820FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000383508FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000400293FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000400295FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000400296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000412106FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000412330FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000413678FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000414440FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000415382FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000415689FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000416863FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000430703FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000430784FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000431360FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000438578FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000441425FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000445218FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000446341FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000448296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000449074FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000450987FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000453105FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000453138FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000453488FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000456476FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000456666FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000462421FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000463430FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000468089FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000470514FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000483957FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000489325FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000495391FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000546633FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000546637FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000547039FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000547489FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000548331FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000548340FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000548614FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000549374FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000550217FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000550435FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000551031FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000552288FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000355991ENST00000552820FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000383508FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000400293FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000400295FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000400296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000412106FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000412330FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000413678FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000414440FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000415382FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000415689FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000416863FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000430703FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000430784FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000431360FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000438578FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000441425FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000445218FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000446341FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000448296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000449074FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000450987FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000453105FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000453138FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000453488FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000456476FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000456666FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000462421FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000463430FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000468089FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000470514FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000483957FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000489325FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000495391FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000546633FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000546637FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000547039FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000547489FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000548331FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000548340FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000548614FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000549374FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000550217FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000550435FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000551031FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000552288FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
5CDS-intronENST00000416776ENST00000552820FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000317568ENST00000376177FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000317568ENST00000396172FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000317568ENST00000417556FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000317568ENST00000458640FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000355991ENST00000376177FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000355991ENST00000396172FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000355991ENST00000417556FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000355991ENST00000458640FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000416776ENST00000376177FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000416776ENST00000396172FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000416776ENST00000417556FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
In-frameENST00000416776ENST00000458640FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-3CDSENST00000531296ENST00000376177FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-3CDSENST00000531296ENST00000396172FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-3CDSENST00000531296ENST00000417556FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-3CDSENST00000531296ENST00000458640FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000383508FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000400293FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000400295FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000400296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000412106FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000412330FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000413678FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000414440FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000415382FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000415689FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000416863FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000430703FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000430784FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000431360FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000438578FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000441425FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000445218FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000446341FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000448296FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000449074FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000450987FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000453105FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000453138FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000453488FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000456476FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000456666FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000462421FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000463430FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000468089FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000470514FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000483957FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000489325FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000495391FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000546633FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000546637FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000547039FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000547489FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000548331FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000548340FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000548614FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000549374FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000550217FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000550435FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000551031FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000552288FRMD8chr11

65172539

+DDX39Bchr6

31503262

-
intron-intronENST00000531296ENST00000552820FRMD8chr11

65172539

+DDX39Bchr6

31503262

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000317568FRMD8chr1165172539+ENST00000376177DDX39Bchr631503262-234814391272100657
ENST00000317568FRMD8chr1165172539+ENST00000396172DDX39Bchr631503262-232514391272109660
ENST00000317568FRMD8chr1165172539+ENST00000417556DDX39Bchr631503262-232514391272109660
ENST00000317568FRMD8chr1165172539+ENST00000458640DDX39Bchr631503262-232514391272109660
ENST00000355991FRMD8chr1165172539+ENST00000376177DDX39Bchr631503262-21421233891894601
ENST00000355991FRMD8chr1165172539+ENST00000396172DDX39Bchr631503262-21191233891903604
ENST00000355991FRMD8chr1165172539+ENST00000417556DDX39Bchr631503262-21191233891903604
ENST00000355991FRMD8chr1165172539+ENST00000458640DDX39Bchr631503262-21191233891903604
ENST00000416776FRMD8chr1165172539+ENST00000376177DDX39Bchr631503262-21881279691940623
ENST00000416776FRMD8chr1165172539+ENST00000396172DDX39Bchr631503262-21651279691949626
ENST00000416776FRMD8chr1165172539+ENST00000417556DDX39Bchr631503262-21651279691949626
ENST00000416776FRMD8chr1165172539+ENST00000458640DDX39Bchr631503262-21651279691949626

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000317568ENST00000376177FRMD8chr1165172539+DDX39Bchr631503262-0.0359928760.96400714
ENST00000317568ENST00000396172FRMD8chr1165172539+DDX39Bchr631503262-0.0266774070.9733226
ENST00000317568ENST00000417556FRMD8chr1165172539+DDX39Bchr631503262-0.0266774070.9733226
ENST00000317568ENST00000458640FRMD8chr1165172539+DDX39Bchr631503262-0.0266774070.9733226
ENST00000355991ENST00000376177FRMD8chr1165172539+DDX39Bchr631503262-0.0262811690.9737188
ENST00000355991ENST00000396172FRMD8chr1165172539+DDX39Bchr631503262-0.0146850910.98531497
ENST00000355991ENST00000417556FRMD8chr1165172539+DDX39Bchr631503262-0.0146850910.98531497
ENST00000355991ENST00000458640FRMD8chr1165172539+DDX39Bchr631503262-0.0146850910.98531497
ENST00000416776ENST00000376177FRMD8chr1165172539+DDX39Bchr631503262-0.0256041330.9743959
ENST00000416776ENST00000396172FRMD8chr1165172539+DDX39Bchr631503262-0.017175630.9828243
ENST00000416776ENST00000417556FRMD8chr1165172539+DDX39Bchr631503262-0.017175630.9828243
ENST00000416776ENST00000458640FRMD8chr1165172539+DDX39Bchr631503262-0.017175630.9828243

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Fusion Genomic Features for FRMD8-DDX39B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FRMD8-DDX39B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:65172539/chr6:31503262)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FRMD8

Q9BZ67

DDX39B

Q13838

FUNCTION: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface (PubMed:29897333, PubMed:29897336). Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6 (PubMed:19572019). {ECO:0000269|PubMed:19572019, ECO:0000269|PubMed:29897333, ECO:0000269|PubMed:29897336}.FUNCTION: Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. May undergo several rounds of ATP hydrolysis during assembly of TREX to drive subsequent loading of components such as ALYREF/THOC and CHTOP onto mRNA. Also associates with pre-mRNA independent of ALYREF/THOC4 and the THO complex. Involved in the nuclear export of intronless mRNA; the ATP-bound form is proposed to recruit export adapter ALYREF/THOC4 to intronless mRNA; its ATPase activity is cooperatively stimulated by RNA and ALYREF/THOC4 and ATP hydrolysis is thought to trigger the dissociation from RNA to allow the association of ALYREF/THOC4 and the NXF1-NXT1 heterodimer. Involved in transcription elongation and genome stability. {ECO:0000269|PubMed:11675789, ECO:0000269|PubMed:15585580, ECO:0000269|PubMed:15833825, ECO:0000269|PubMed:15998806, ECO:0000269|PubMed:17190602, ECO:0000269|PubMed:17562711, ECO:0000269|PubMed:17984224, ECO:0000269|PubMed:20844015, ECO:0000269|PubMed:22144908, ECO:0000269|PubMed:23222130, ECO:0000269|PubMed:23299939, ECO:0000269|PubMed:9242493}.; FUNCTION: Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro. The ATPase and helicase activities are not influenced by U2AF2; the effect of ALYREF/THOC4 is reported conflictingly with [PubMed:23299939] reporting a stimulatory effect. {ECO:0000269|PubMed:23299939, ECO:0000269|PubMed:9242493}.; FUNCTION: (Microbial infection) The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. {ECO:0000269|PubMed:18974867}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFRMD8chr11:65172539chr6:31503262ENST00000317568+101130_376425465.0DomainFERM
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000383508013261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000038350801376_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000396172411261_422205429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000400295011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000040029501176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000400296011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000040029601176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000412106013261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041210601376_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000412330011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041233001176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000413678011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041367801176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000414440013261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041444001376_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000415689011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041568901176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000416863011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041686301176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000430784011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000043078401176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000431360011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000043136001176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000441425011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044142501176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000445218013261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044521801376_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000448296011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044829601176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000453138011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045313801176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000456476011261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045647601176_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000456666013261_4220429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045666601376_2490429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000458640411261_422205429.0DomainHelicase C-terminal
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000383508013196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000038350801345_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000400295011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000040029501145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000400296011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000040029601145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000412106013196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041210601345_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000412330011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041233001145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000413678011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041367801145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000414440013196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041444001345_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000415689011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041568901145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000416863011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041686301145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000430784011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000043078401145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000431360011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000043136001145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000441425011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044142501145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000445218013196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044521801345_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000448296011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044829601145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000453138011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045313801145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000456476011196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045647601145_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000456666013196_1990429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045666601345_730429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000038350801389_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000040029501189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000040029601189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041210601389_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041233001189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041367801189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041444001389_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041568901189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000041686301189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000043078401189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000043136001189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044142501189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044521801389_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000044829601189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045313801189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045647601189_960429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045666601389_960429.0Nucleotide bindingNote=ATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFRMD8chr11:65172539chr6:31503262ENST00000355991+91030_376369409.0DomainFERM
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000039617241176_249205429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045864041176_249205429.0DomainHelicase ATP-binding
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000396172411196_199205429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000039617241145_73205429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST00000458640411196_199205429.0MotifNote=DECD box
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045864041145_73205429.0MotifNote=Q motif
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000039617241189_96205429.0Nucleotide bindingNote=ATP
TgeneDDX39Bchr11:65172539chr6:31503262ENST0000045864041189_96205429.0Nucleotide bindingNote=ATP


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Fusion Gene Sequence for FRMD8-DDX39B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>31378_31378_1_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000376177_length(transcript)=2348nt_BP=1439nt
GCCTCGGGCGCCGCGCTTCCTCCCGCCGTGGCTTCCGCGTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGG
CGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGG
CAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTGGGAGCCCGAGCGGCTGACGTGCTGGTATACCT
AGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCATGAGCTGCACCGCGCTGTCCGCGAGGTCCTGCA
GCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAA
GCTGGGACGCCAGTGGCCGGAGCTGCTGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCG
AAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGT
GCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGG
CCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCT
CCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTG
CGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGT
TGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAG
CAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCT
GGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGA
GTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGC
TCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGA
CATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCG
TCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTA
CGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTC
TGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAG
GCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGT
GAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGTGCTACCCTCTGTCTCCCTCCAGGTGGCCAGAGCA
GGCCGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAG
GTCAATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACC
GTCTGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCT
TTTGCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTTTTTTTTAACAAAACTAAAAATGAAACACATGTGTCTGTGGT

>31378_31378_1_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000376177_length(amino acids)=657AA_BP=437
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDC
EALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYL
LKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVN
KLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMT
PHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLV
EQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRCYPLSPSRWPEQAGLAPRAWLSHL

--------------------------------------------------------------
>31378_31378_2_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000396172_length(transcript)=2325nt_BP=1439nt
GCCTCGGGCGCCGCGCTTCCTCCCGCCGTGGCTTCCGCGTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGG
CGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGG
CAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTGGGAGCCCGAGCGGCTGACGTGCTGGTATACCT
AGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCATGAGCTGCACCGCGCTGTCCGCGAGGTCCTGCA
GCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAA
GCTGGGACGCCAGTGGCCGGAGCTGCTGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCG
AAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGT
GCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGG
CCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCT
CCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTG
CGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGT
TGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAG
CAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCT
GGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGA
GTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGC
TCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGA
CATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCG
TCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTA
CGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTC
TGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAG
GCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGT
GAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTT
GGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGA
TGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACAC
CAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAA

>31378_31378_2_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000396172_length(amino acids)=660AA_BP=437
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDC
EALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYL
LKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVN
KLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMT
PHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLV
EQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAK

--------------------------------------------------------------
>31378_31378_3_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000417556_length(transcript)=2325nt_BP=1439nt
GCCTCGGGCGCCGCGCTTCCTCCCGCCGTGGCTTCCGCGTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGG
CGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGG
CAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTGGGAGCCCGAGCGGCTGACGTGCTGGTATACCT
AGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCATGAGCTGCACCGCGCTGTCCGCGAGGTCCTGCA
GCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAA
GCTGGGACGCCAGTGGCCGGAGCTGCTGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCG
AAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGT
GCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGG
CCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCT
CCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTG
CGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGT
TGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAG
CAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCT
GGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGA
GTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGC
TCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGA
CATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCG
TCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTA
CGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTC
TGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAG
GCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGT
GAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTT
GGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGA
TGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACAC
CAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAA

>31378_31378_3_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000417556_length(amino acids)=660AA_BP=437
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDC
EALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYL
LKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVN
KLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMT
PHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLV
EQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAK

--------------------------------------------------------------
>31378_31378_4_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000458640_length(transcript)=2325nt_BP=1439nt
GCCTCGGGCGCCGCGCTTCCTCCCGCCGTGGCTTCCGCGTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGG
CGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGG
CAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTGGGAGCCCGAGCGGCTGACGTGCTGGTATACCT
AGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCATGAGCTGCACCGCGCTGTCCGCGAGGTCCTGCA
GCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAA
GCTGGGACGCCAGTGGCCGGAGCTGCTGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCG
AAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGT
GCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGG
CCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCT
CCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTG
CGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGT
TGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAG
CAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCT
GGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGA
GTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGC
TCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGA
CATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCG
TCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTA
CGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTC
TGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAG
GCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGT
GAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTT
GGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGA
TGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACAC
CAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAA

>31378_31378_4_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000317568_DDX39B_chr6_31503262_ENST00000458640_length(amino acids)=660AA_BP=437
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDC
EALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYL
LKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVN
KLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMT
PHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLV
EQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAK

--------------------------------------------------------------
>31378_31378_5_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000376177_length(transcript)=2142nt_BP=1233nt
GTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCT
TGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACC
GAAGCAGCGTGTCCTCCGTGGGAGCCCGAGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAAGCTGGGACGCCAGTGGCCGGAGCTGC
TGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGC
GGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACG
TGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGG
AGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGC
CGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACC
GCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGC
ACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCC
TGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCA
CACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGG
CGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGA
GGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTT
TTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAG
ATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGA
ACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCC
AGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAG
ATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGC
CTGAGGATTCTGACACCTACCTGCATCGGTGCTACCCTCTGTCTCCCTCCAGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTTGGC
TATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGATGA
GATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACACCAG
GGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAACCC

>31378_31378_5_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000376177_length(amino acids)=601AA_BP=381
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGAREVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKR
RELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAG
PGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLG
LRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLR
RQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEK
NRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDM

--------------------------------------------------------------
>31378_31378_6_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000396172_length(transcript)=2119nt_BP=1233nt
GTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCT
TGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACC
GAAGCAGCGTGTCCTCCGTGGGAGCCCGAGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAAGCTGGGACGCCAGTGGCCGGAGCTGC
TGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGC
GGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACG
TGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGG
AGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGC
CGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACC
GCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGC
ACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCC
TGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCA
CACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGG
CGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGA
GGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTT
TTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAG
ATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGA
ACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCC
AGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAG
ATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGC
CTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGA
ATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTG
AACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTAC
TGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTT

>31378_31378_6_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000396172_length(amino acids)=604AA_BP=381
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGAREVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKR
RELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAG
PGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLG
LRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLR
RQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEK
NRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDM

--------------------------------------------------------------
>31378_31378_7_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000417556_length(transcript)=2119nt_BP=1233nt
GTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCT
TGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACC
GAAGCAGCGTGTCCTCCGTGGGAGCCCGAGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAAGCTGGGACGCCAGTGGCCGGAGCTGC
TGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGC
GGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACG
TGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGG
AGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGC
CGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACC
GCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGC
ACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCC
TGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCA
CACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGG
CGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGA
GGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTT
TTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAG
ATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGA
ACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCC
AGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAG
ATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGC
CTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGA
ATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTG
AACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTAC
TGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTT

>31378_31378_7_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000417556_length(amino acids)=604AA_BP=381
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGAREVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKR
RELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAG
PGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLG
LRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLR
RQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEK
NRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDM

--------------------------------------------------------------
>31378_31378_8_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000458640_length(transcript)=2119nt_BP=1233nt
GTCGCTTCCCGGTCAGCTGCGTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCT
TGCCTCTCAGGTGGCGGGCTCTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACC
GAAGCAGCGTGTCCTCCGTGGGAGCCCGAGAGGTGCAGCTGAAACCCAAGCACCAGCCCTACAAGCTGGGACGCCAGTGGCCGGAGCTGC
TGCTGCGCTTCACCAGTGCCCCAGACGATGACGTGGCCATGGATGAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGC
GGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTATGAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACG
TGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAGCTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGG
AGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGCCAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGC
CGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAGGTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACC
GCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGTGCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGC
ACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAAGGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCC
TGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAGGAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCA
CACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAACTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGG
CGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCGGACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGA
GGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACCATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTT
TTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCTACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAG
ATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTGCATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGA
ACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAGGTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCC
AGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGTGGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAG
ATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGAGGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGC
CTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGA
ATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTG
AACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTAC
TGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTT

>31378_31378_8_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000355991_DDX39B_chr6_31503262_ENST00000458640_length(amino acids)=604AA_BP=381
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGAREVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKR
RELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAG
PGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLG
LRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLR
RQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEK
NRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDM

--------------------------------------------------------------
>31378_31378_9_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000376177_length(transcript)=2188nt_BP=1279nt
GTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCT
CTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTG
GGAGCCCGAGCGGCTGACGTGCTGGTATACCTAGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCAT
GAGCTGCACCGCGCTGTCCGCGAGGTCCTGCAGCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAT
GAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTAT
GAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAG
CTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGC
CAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAG
GTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGT
GCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAA
GGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAG
GAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAA
CTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCG
GACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACC
ATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCT
ACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTG
CATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAG
GTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGT
GGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGA
GGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGTGCTACCCTCTGTCT
CCCTCCAGGTGGCCAGAGCAGGCCGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATG
ATGTGCAGGATCGCTTTGAGGTCAATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTC
GCCCATTTTGGAATGTGACCGTCTGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCC
CCACCCCATGGCTTCCATCTTTTGCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTTTTTTTTAACAAAACTAAAAAT

>31378_31378_9_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000376177_length(amino acids)=623AA_BP=403
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLP
AHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPV
SVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQD
SATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVD
DETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILV

--------------------------------------------------------------
>31378_31378_10_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000396172_length(transcript)=2165nt_BP=1279nt
GTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCT
CTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTG
GGAGCCCGAGCGGCTGACGTGCTGGTATACCTAGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCAT
GAGCTGCACCGCGCTGTCCGCGAGGTCCTGCAGCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAT
GAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTAT
GAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAG
CTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGC
CAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAG
GTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGT
GCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAA
GGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAG
GAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAA
CTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCG
GACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACC
ATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCT
ACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTG
CATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAG
GTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGT
GGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGA
GGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGC
CGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTC
AATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTC
TGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTT
GCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTTTTTTTTAACAAAACTAAAAATGAAACACATGTGTCTGTGGTATC

>31378_31378_10_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000396172_length(amino acids)=626AA_BP=403
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLP
AHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPV
SVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQD
SATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVD
DETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILV

--------------------------------------------------------------
>31378_31378_11_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000417556_length(transcript)=2165nt_BP=1279nt
GTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCT
CTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTG
GGAGCCCGAGCGGCTGACGTGCTGGTATACCTAGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCAT
GAGCTGCACCGCGCTGTCCGCGAGGTCCTGCAGCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAT
GAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTAT
GAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAG
CTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGC
CAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAG
GTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGT
GCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAA
GGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAG
GAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAA
CTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCG
GACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACC
ATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCT
ACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTG
CATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAG
GTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGT
GGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGA
GGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGC
CGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTC
AATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTC
TGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTT
GCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTTTTTTTTAACAAAACTAAAAATGAAACACATGTGTCTGTGGTATC

>31378_31378_11_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000417556_length(amino acids)=626AA_BP=403
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLP
AHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPV
SVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQD
SATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVD
DETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILV

--------------------------------------------------------------
>31378_31378_12_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000458640_length(transcript)=2165nt_BP=1279nt
GTCCTTAGCGGGAGCCCGAGTGCGGGCGGTGGCGGGCTTGGCGGCGGGGCAGGATTCCAGGCAGGAGCCTTGCCTCTCAGGTGGCGGGCT
CTGCGACCCTGCGAGATGGACGGGACAGAAGGCAGTGCCGGGCAGCCCGGCCCCGCTGAGCGATCCCACCGAAGCAGCGTGTCCTCCGTG
GGAGCCCGAGCGGCTGACGTGCTGGTATACCTAGCGGATGACACGGTGGTGCCCCTGGCTGTGGAGAACCTGCCCTCGCTCAGTGCCCAT
GAGCTGCACCGCGCTGTCCGCGAGGTCCTGCAGCTTCCAGACATCGCCCTGGATGTCTTCGCGCTCTGGCTGGTCTCCCCTCTGCTGGAT
GAGCCTTTCCTGCAGTTCCGAAGGAACGTGTTCTTCCCAAAGCGGCGGGAGCTCCAGATCCATGACGAGGAGGTCCTGCGGCTGCTCTAT
GAGGAGGCCAAGGGCAACGTGCTGGCTGCACGGTACCCGTGCGACGTGGAGGACTGCGAGGCTCTGGGCGCCCTGGTGTGCCGCGTGCAG
CTTGGGCCCTACCAGCCCGGCCGGCCGGCAGCCTGCGACCTGAGGGAGAAGCTGGACTCCTTCCTCCCTGCCCACCTCTGTAAGCGGGGC
CAGAGTCTCTTTGCTGCCCTCCGGGGCCGTGGGGCCAGGGCCGGGCCGGGCGAGCAGGGCCTGCTGAACGCCTACCGCCAGGTGCAGGAG
GTCAGCAGCGACGGCGGGTGCGAGGCCGCCCTGGGCACCCACTACCGCGCCTATCTCCTCAAGTGCCACGAGCTGCCGTTTTATGGGTGT
GCCTTCTTCCACGGTGAGGTTGACAAGCCGGCCCAAGGCTTTTTGCACCGGGGTGGGCGCAAGCCAGTTTCTGTGGCCATCAGTCTGGAA
GGCGTGCACGTCATCGATAGCAGAGAGAAGCATGTCCTGCTGGGCCTGCGCTTCCAGGAGCTGTCGTGGGACCACACCTCCCCCGAGGAG
GAGGAGCCCATCTTGTGGCTGGAGTTCGACGGGGACAGCGAGGGCACACCTGTCAACAAGCTCCTCAAGATCTACTCCAAGCAGGCCGAA
CTGATGAGCAGTCTCATTGAGTACTGCATCGAACTGAGCCAGGCGGCGGAGCCCGCAGGCCCCCAGGACAGTGCGACTGGCTCGCCCTCG
GACCCCAGCTCCTCACTGGCTCCTGTTCAGCGCCCCAAGCTGCGGAGGCAGGGCAGTGTGGTGTCCAGCCGGATCCAGCATCTCTCCACC
ATCGACTACGTGGAGGACGACATGCGTCGGGATGTCCAGGAAATTTTTCGCATGACCCCCCACGAGAAGCAGGTCATGATGTTCAGTGCT
ACCTTGAGCAAAGAGATCCGTCCAGTCTGCCGCAAGTTCATGCAAGATCCAATGGAGATCTTCGTGGATGATGAGACGAAGTTGACGCTG
CATGGGTTGCAGCAGTACTACGTGAAACTGAAGGACAACGAGAAGAACCGGAAGCTCTTTGACCTTCTGGATGTCCTTGAGTTCAACCAG
GTGGTGATCTTTGTGAAGTCTGTGCAGCGGTGCATTGCCTTGGCCCAGCTACTAGTGGAGCAGAACTTCCCAGCCATTGCCATCCACCGT
GGGATGCCCCAGGAGGAGAGGCTTTCTCGGTATCAGCAGTTTAAAGATTTTCAACGACGAATTCTTGTGGCTACCAACCTATTTGGCCGA
GGCATGGACATCGAGCGGGTGAACATTGCTTTTAATTATGACATGCCTGAGGATTCTGACACCTACCTGCATCGGGTGGCCAGAGCAGGC
CGGTTTGGCACCAAGGGCTTGGCTATCACATTTGTGTCCGATGAGAATGATGCCAAGATCCTCAATGATGTGCAGGATCGCTTTGAGGTC
AATATTAGTGAGCTGCCTGATGAGATAGACATCTCCTCCTACATTGAACAGACACGGTAGAAGACTCGCCCATTTTGGAATGTGACCGTC
TGTCCTTCAGGAGAGGACACCAGGGTGGGGGTGAAGGAGACACTACTGCCCCCACCCCTGACAGCCCCCACCCCATGGCTTCCATCTTTT
GCATCACCACCACTCCTGAACCCCCATTTCTGATTTGTCAGAATTTTTTTTTAACAAAACTAAAAATGAAACACATGTGTCTGTGGTATC

>31378_31378_12_FRMD8-DDX39B_FRMD8_chr11_65172539_ENST00000416776_DDX39B_chr6_31503262_ENST00000458640_length(amino acids)=626AA_BP=403
MPLRWRALRPCEMDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALW
LVSPLLDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLP
AHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPV
SVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQD
SATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVD
DETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FRMD8-DDX39B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FRMD8-DDX39B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FRMD8-DDX39B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource