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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FUT8-IFT52 (FusionGDB2 ID:31848)

Fusion Gene Summary for FUT8-IFT52

check button Fusion gene summary
Fusion gene informationFusion gene name: FUT8-IFT52
Fusion gene ID: 31848
HgeneTgene
Gene symbol

FUT8

IFT52

Gene ID

2530

51098

Gene namefucosyltransferase 8intraflagellar transport 52
SynonymsCDGF|CDGF1C20orf9|CGI-53|NGD2|NGD5
Cytomap

14q23.3

20q13.12

Type of geneprotein-codingprotein-coding
Descriptionalpha-(1,6)-fucosyltransferaseGDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferaseGDP-fucose--glycoprotein fucosyltransferasealpha1-6FucTfucosyltransferase 8 (alpha (1,6) fucosyltransferase)glycoprotein 6-alpha-L-fucosyltransferaseintraflagellar transport protein 52 homologprotein NGD5 homolog
Modification date2020032220200315
UniProtAcc.

Q9Y366

Ensembl transtripts involved in fusion geneENST00000358307, ENST00000360689, 
ENST00000394585, ENST00000394586, 
ENST00000417683, ENST00000557164, 
ENST00000554765, 		ENST00000471199, 
ENST00000373030, ENST00000373039, 
Fusion gene scores* DoF score15 X 10 X 7=10507 X 7 X 6=294
# samples 187
** MAII scorelog2(18/1050*10)=-2.54432051622381
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/294*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FUT8 [Title/Abstract] AND IFT52 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFUT8(66209024)-IFT52(42232476), # samples:1
Anticipated loss of major functional domain due to fusion event.FUT8-IFT52 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
FUT8-IFT52 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFUT8

GO:0018279

protein N-linked glycosylation via asparagine

17172260

HgeneFUT8

GO:0046368

GDP-L-fucose metabolic process

17172260


check buttonFusion gene breakpoints across FUT8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IFT52 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABF996799FUT8chr14

66209024

-IFT52chr20

42232476

+


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Fusion Gene ORF analysis for FUT8-IFT52

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000358307ENST00000471199FUT8chr14

66209024

-IFT52chr20

42232476

+
5CDS-intronENST00000360689ENST00000471199FUT8chr14

66209024

-IFT52chr20

42232476

+
5CDS-intronENST00000394585ENST00000471199FUT8chr14

66209024

-IFT52chr20

42232476

+
5CDS-intronENST00000394586ENST00000471199FUT8chr14

66209024

-IFT52chr20

42232476

+
5CDS-intronENST00000417683ENST00000471199FUT8chr14

66209024

-IFT52chr20

42232476

+
5CDS-intronENST00000557164ENST00000471199FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000360689ENST00000373030FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000360689ENST00000373039FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000394585ENST00000373030FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000394585ENST00000373039FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000417683ENST00000373030FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000417683ENST00000373039FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000557164ENST00000373030FUT8chr14

66209024

-IFT52chr20

42232476

+
Frame-shiftENST00000557164ENST00000373039FUT8chr14

66209024

-IFT52chr20

42232476

+
In-frameENST00000358307ENST00000373030FUT8chr14

66209024

-IFT52chr20

42232476

+
In-frameENST00000358307ENST00000373039FUT8chr14

66209024

-IFT52chr20

42232476

+
In-frameENST00000394586ENST00000373030FUT8chr14

66209024

-IFT52chr20

42232476

+
In-frameENST00000394586ENST00000373039FUT8chr14

66209024

-IFT52chr20

42232476

+
intron-3CDSENST00000554765ENST00000373030FUT8chr14

66209024

-IFT52chr20

42232476

+
intron-3CDSENST00000554765ENST00000373039FUT8chr14

66209024

-IFT52chr20

42232476

+
intron-intronENST00000554765ENST00000471199FUT8chr14

66209024

-IFT52chr20

42232476

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394586FUT8chr1466209024-ENST00000373030IFT52chr2042232476+4688334510932571492
ENST00000394586FUT8chr1466209024-ENST00000373039IFT52chr2042232476+4614334510932571492
ENST00000358307FUT8chr1466209024-ENST00000373030IFT52chr2042232476+379324502911676461
ENST00000358307FUT8chr1466209024-ENST00000373039IFT52chr2042232476+371924502911676461

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394586ENST00000373030FUT8chr1466209024-IFT52chr2042232476+0.0004956150.9995043
ENST00000394586ENST00000373039FUT8chr1466209024-IFT52chr2042232476+0.0005199840.99948007
ENST00000358307ENST00000373030FUT8chr1466209024-IFT52chr2042232476+0.0008779590.9991221
ENST00000358307ENST00000373039FUT8chr1466209024-IFT52chr2042232476+0.0009079130.9990921

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Fusion Genomic Features for FUT8-IFT52


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for FUT8-IFT52


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:66209024/chr20:42232476)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IFT52

Q9Y366

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia (PubMed:27466190). Required for the anterograde transport of IFT88 (PubMed:27466190). {ECO:0000269|PubMed:27466190}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneIFT52chr14:66209024chr20:42232476ENST00000373030014348_3510438.0Compositional biasNote=Poly-Pro
TgeneIFT52chr14:66209024chr20:42232476ENST00000373039014348_3510438.0Compositional biasNote=Poly-Pro

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFUT8chr14:66209024chr20:42232476ENST00000360689-111206_4930576.0DomainGT23
HgeneFUT8chr14:66209024chr20:42232476ENST00000360689-111502_5630576.0DomainSH3
HgeneFUT8chr14:66209024chr20:42232476ENST00000394585-111206_4930576.0DomainGT23
HgeneFUT8chr14:66209024chr20:42232476ENST00000394585-111502_5630576.0DomainSH3
HgeneFUT8chr14:66209024chr20:42232476ENST00000394586-110206_4930576.0DomainGT23
HgeneFUT8chr14:66209024chr20:42232476ENST00000394586-110502_5630576.0DomainSH3
HgeneFUT8chr14:66209024chr20:42232476ENST00000417683-13206_4930170.0DomainGT23
HgeneFUT8chr14:66209024chr20:42232476ENST00000417683-13502_5630170.0DomainSH3
HgeneFUT8chr14:66209024chr20:42232476ENST00000557164-110206_4930413.0DomainGT23
HgeneFUT8chr14:66209024chr20:42232476ENST00000557164-110502_5630413.0DomainSH3
HgeneFUT8chr14:66209024chr20:42232476ENST00000360689-111299_3050576.0MotifSH3-binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000394585-111299_3050576.0MotifSH3-binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000394586-110299_3050576.0MotifSH3-binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000417683-13299_3050170.0MotifSH3-binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000557164-110299_3050413.0MotifSH3-binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000360689-111365_3660576.0RegionNote=Important for donor substrate binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000394585-111365_3660576.0RegionNote=Important for donor substrate binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000394586-110365_3660576.0RegionNote=Important for donor substrate binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000417683-13365_3660170.0RegionNote=Important for donor substrate binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000557164-110365_3660413.0RegionNote=Important for donor substrate binding
HgeneFUT8chr14:66209024chr20:42232476ENST00000360689-1111_90576.0Topological domainCytoplasmic
HgeneFUT8chr14:66209024chr20:42232476ENST00000360689-11131_5750576.0Topological domainLumenal
HgeneFUT8chr14:66209024chr20:42232476ENST00000394585-1111_90576.0Topological domainCytoplasmic
HgeneFUT8chr14:66209024chr20:42232476ENST00000394585-11131_5750576.0Topological domainLumenal
HgeneFUT8chr14:66209024chr20:42232476ENST00000394586-1101_90576.0Topological domainCytoplasmic
HgeneFUT8chr14:66209024chr20:42232476ENST00000394586-11031_5750576.0Topological domainLumenal
HgeneFUT8chr14:66209024chr20:42232476ENST00000417683-131_90170.0Topological domainCytoplasmic
HgeneFUT8chr14:66209024chr20:42232476ENST00000417683-1331_5750170.0Topological domainLumenal
HgeneFUT8chr14:66209024chr20:42232476ENST00000557164-1101_90413.0Topological domainCytoplasmic
HgeneFUT8chr14:66209024chr20:42232476ENST00000557164-11031_5750413.0Topological domainLumenal
HgeneFUT8chr14:66209024chr20:42232476ENST00000360689-11110_300576.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneFUT8chr14:66209024chr20:42232476ENST00000394585-11110_300576.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneFUT8chr14:66209024chr20:42232476ENST00000394586-11010_300576.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneFUT8chr14:66209024chr20:42232476ENST00000417683-1310_300170.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneFUT8chr14:66209024chr20:42232476ENST00000557164-11010_300413.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for FUT8-IFT52


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>31848_31848_1_FUT8-IFT52_FUT8_chr14_66209024_ENST00000358307_IFT52_chr20_42232476_ENST00000373030_length(transcript)=3793nt_BP=2450nt
GCTCTGCCTCAGTCAGTGGCGCCGAAGGCTCCGTTAAGCGGCGGCGGCGGTTCCTGTTTCCGTTTCTTCCTCTCCGTTCGGTCGGGAGTA
GCATCCTCCACTCAGCCACCCTTCCCACTCCCCCATCGTGGGGCAGCTGCGGCTGAGGGCTGTGGCTTTGGCAGCTGCGACGGGGAGCGG
CGGAGACCGCCTCTGCTCCCGCCTGGGGTTGCTGCTTTTGCTCAGAGGACATCCATGACCCTAATGGTCTTTTTGTTCAAGATAAAGTGA
TTTTTTGCCTTTGTTGATTAACTGGACAAATTCAGGATACCAGAAGGCCCTATTGATCAGGGGCCAGCTATAGGAAGAGTACGCGTTTTA
GAAGAGCAGCTTGTTAAGGCCAAAGAACAGATTGAAAATTACAAGAAACAGACCAGAAATGGTCTGGGGAAGGATCATGAAATCCTGAGG
AGGAGGATTGAAAATGGAGCTAAAGAGCTCTGGTTTTTCCTACAGAGTGAATTGAAGAAATTAAAGAACTTAGAAGGAAATGAACTCCAA
AGACATGCAGATGAATTTCTTTTGGATTTAGGACATCATGAAAGGATTCTGATGGCAATTACTGTCTCATTAGTGAACAATAAAAGAAAA
ATTGTTGTATTAGCACAACCTACTACTGTGAAGAGGAAAAGAATTACCCCATACAAGTCTATAATGACGGATCTATACTACCTCAGTCAG
ACAGATGGAGCAGGTGATTGGCGGGAAAAAGAGGCCAAAGATCTGACAGAACTGGTTCAGCGGAGAATAACATATCTTCAGAATCCCAAG
GACTGCAGCAAAGCCAAAAAGCTGGTGTGTAATATCAACAAAGGCTGTGGCTATGGCTGTCAGCTCCATCATGTGGTCTACTGCTTCATG
ATTGCATATGGCACCCAGCGAACACTCATCTTGGAATCTCAGAATTGGCGCTATGCTACTGGTGGATGGGAGACTGTATTTAGGCCTGTA
AGTGAGACATGCACAGACAGATCTGGCATCTCCACTGGACACTGGTCAGGTGAAGTGAAGGACAAAAATGTTCAAGTGGTCGAGCTTCCC
ATTGTAGACAGTCTTCATCCCCGTCCTCCATATTTACCCTTGGCTGTACCAGAAGACCTCGCAGATCGACTTGTACGAGTGCATGGTGAC
CCTGCAGTGTGGTGGGTGTCTCAGTTTGTCAAATACTTGATCCGCCCACAGCCTTGGCTAGAAAAAGAAATAGAAGAAGCCACCAAGAAG
CTTGGCTTCAAACATCCAGTTATTGGAGTCCATGTCAGACGCACAGACAAAGTGGGAACAGAAGCTGCCTTCCATCCCATTGAAGAGTAC
ATGGTGCATGTTGAAGAACATTTTCAGCTTCTTGCACGCAGAATGCAAGTGGACAAAAAAAGAGTGTATTTGGCCACAGATGACCCTTCT
TTATTAAAGGAGGCAAAAACAAAGTACCCCAATTATGAATTTATTAGTGATAACTCTATTTCCTGGTCAGCTGGACTGCACAATCGATAC
ACAGAAAATTCACTTCGTGGAGTGATCCTGGATATACATTTTCTCTCTCAGGCAGACTTCCTAGTGTGTACTTTTTCATCCCAGGTGTCA
ACAGGAAATTGGGAAGGACGGGCCTATATCCCTCCTACAAAGTTCGAGAGAAGATAGAAACGGTCAAGTACCCCACATATCCTGAGGCTG
AGAAATAAAGCTCAGATGGAAGAGATAAACGACCAAACTCAGTTCGACCAAACTCAGTTCAAACCATTTCAGCCAAACTGTAGATGAAGA
GGGCTCTGATCTAACAAAATAAGGTTATATGAGTAGATACTCTCAGCACCAAGAGCAGCTGGGAACTGACATAGGCTTCAATTGGTGGAA
TTCCTCTTTAACAAGGGCTGCAATGCCCTCATACCCATGCACAGTACAATAATGTACTCACATATAACATGCAAACAGGTTGTTTTCTAC
TTTGCCCCTTTCAGTATGTCCCCATAAGACAAACACTGCCATATTGTGTAATTTAAGTGACACAGACATTTTGTGTGAGACTTAAAACAT
GGTGCCTATATCTGAGAGACCTGTGTGAACTATTGAGAAGATCGGAACAGCTCCTTACTCTGAGGAAGTTGATTCTTATTTGATGGTGGT
ATTGTGACCACTGAATTCACTCCAGTCAACAGATTCAGAATGAGAATGGACGTTTGGTTTTTTTTTGTTTTTGTTTTTGTTTTTTCCTTT
ATAAGGTTGTCTGTTTTTTTTTTTTTAAATAATTGCATCAGTTCATTGACCTCATCATTAATAAGTGAAGAATACATCAGAAAATAAAAT
ATTCACTCTCCATTAGAAAATTTTGTAAAACAATGCCATGAACAAATTCTTTAGTACTCAATGTTTCTGGACATTCTCTTTGATAACAAA
AAATAAATTTTAAAAAGGAATGACACCAATATTAACTTTTTACTAGAAGAATATGGAATCATGGTTAATAATGATGCTGTGGTTAGAAAT
GTATATCACAAATATTTCCATCCTAAAGAAGCTCTAGTTTCCAGTGGAGTCTTGAACAGGGAAATTAGCCGAGCTGCAGGAAAGGCTGTG
CCTGGGATCATTGATGAGGAAAGCAGTGGAAACAATGCCCAGGCTCTCACCTTTGTGTATCCTTTTGGTGCCACATTGAGTGTCATGAAA
CCAGCAGTGGCGGTTCTGTCTACAGGTTCTGTCTGCTTCCCACTTAACAGACCCATTTTGGCTTTCTATCACTCAAAGAACCAAGGTGGG
AAGCTGGCAGTGCTTGGTTCATGTCACATGTTCAGTGATCAATATTTGGACAAAGAAGAAAACAGCAAAATCATGGATGTTGTTTTCCAG
TGGCTCACGACAGGAGACATCCACCTAAACCAGATTGATGCTGAGGACCCAGAGATTTCTGACTACATGATGCTGCCCTACACAGCCACC
CTATCAAAGCGGAATCGAGAGTGTCTCCAGGAGAGTGATGAGATCCCAAGGGACTTTACCACCCTCTTCGACCTGTCCATCTTCCAGCTG
GATACCACCTCCTTCCACAGCGTCATCGAGGCTCACGAGCAGCTAAATGTGAAACATGAACCACTCCAGCTCATCCAGCCTCAGTTTGAG
ACGCCGCTGCCAACCCTTCAGCCTGCGGTTTTTCCTCCCAGTTTCCGGGAGTTACCACCTCCTCCTCTGGAGCTATTTGATTTAGATGAA
ACGTTCTCCTCTGAGAAGGCACGGCTGGCTCAGATTACCAATAAGTGTACTGAAGAAGACCTGGAATTTTATGTCAGGAAGTGTGGTGAT
ATTCTTGGAGTAACCAGTAAACTACCAAAGGACCAACAGGATGCCAAACATATCCTTGAGCACGTCTTCTTCCAAGTGGTGGAGTTCAAG
AAATTGAACCAGGAACATGACATCGATACAAGTGAAACAGCATTCCAGAACAATTTCTGAAGACCATGCCTCTTGAAGCTTTTTCTGCCT
CCTGATTCTCTCTTTGTAAACTATTTTCAAATTGTTTTTCAACTCCTTATCAAAATTGTTTATACACTCTTTCCTCCATGAGCTCTGGAA
GGTATATGCATCTTCTGTAATACTCAGATAGGTATAAGATTTTTCACAAAATCCTTATGTAAGATACATTCCATTTTTAAAAATTAAATG
TATGGTTGCATCTGTCTTTTTATACCCTATGAAACAGTCTTGATTTTTTTTTCTCAACCCCAGTTCTGGATTTGAGTCTTTTATCAAAGA

>31848_31848_1_FUT8-IFT52_FUT8_chr14_66209024_ENST00000358307_IFT52_chr20_42232476_ENST00000373030_length(amino acids)=461AA_BP=
MDKFRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFL
LDLGHHERILMAITVSLVNNKRKIVVLAQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKK
LVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHP
RPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEH
FQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVSTGNWEGR

--------------------------------------------------------------
>31848_31848_2_FUT8-IFT52_FUT8_chr14_66209024_ENST00000358307_IFT52_chr20_42232476_ENST00000373039_length(transcript)=3719nt_BP=2450nt
GCTCTGCCTCAGTCAGTGGCGCCGAAGGCTCCGTTAAGCGGCGGCGGCGGTTCCTGTTTCCGTTTCTTCCTCTCCGTTCGGTCGGGAGTA
GCATCCTCCACTCAGCCACCCTTCCCACTCCCCCATCGTGGGGCAGCTGCGGCTGAGGGCTGTGGCTTTGGCAGCTGCGACGGGGAGCGG
CGGAGACCGCCTCTGCTCCCGCCTGGGGTTGCTGCTTTTGCTCAGAGGACATCCATGACCCTAATGGTCTTTTTGTTCAAGATAAAGTGA
TTTTTTGCCTTTGTTGATTAACTGGACAAATTCAGGATACCAGAAGGCCCTATTGATCAGGGGCCAGCTATAGGAAGAGTACGCGTTTTA
GAAGAGCAGCTTGTTAAGGCCAAAGAACAGATTGAAAATTACAAGAAACAGACCAGAAATGGTCTGGGGAAGGATCATGAAATCCTGAGG
AGGAGGATTGAAAATGGAGCTAAAGAGCTCTGGTTTTTCCTACAGAGTGAATTGAAGAAATTAAAGAACTTAGAAGGAAATGAACTCCAA
AGACATGCAGATGAATTTCTTTTGGATTTAGGACATCATGAAAGGATTCTGATGGCAATTACTGTCTCATTAGTGAACAATAAAAGAAAA
ATTGTTGTATTAGCACAACCTACTACTGTGAAGAGGAAAAGAATTACCCCATACAAGTCTATAATGACGGATCTATACTACCTCAGTCAG
ACAGATGGAGCAGGTGATTGGCGGGAAAAAGAGGCCAAAGATCTGACAGAACTGGTTCAGCGGAGAATAACATATCTTCAGAATCCCAAG
GACTGCAGCAAAGCCAAAAAGCTGGTGTGTAATATCAACAAAGGCTGTGGCTATGGCTGTCAGCTCCATCATGTGGTCTACTGCTTCATG
ATTGCATATGGCACCCAGCGAACACTCATCTTGGAATCTCAGAATTGGCGCTATGCTACTGGTGGATGGGAGACTGTATTTAGGCCTGTA
AGTGAGACATGCACAGACAGATCTGGCATCTCCACTGGACACTGGTCAGGTGAAGTGAAGGACAAAAATGTTCAAGTGGTCGAGCTTCCC
ATTGTAGACAGTCTTCATCCCCGTCCTCCATATTTACCCTTGGCTGTACCAGAAGACCTCGCAGATCGACTTGTACGAGTGCATGGTGAC
CCTGCAGTGTGGTGGGTGTCTCAGTTTGTCAAATACTTGATCCGCCCACAGCCTTGGCTAGAAAAAGAAATAGAAGAAGCCACCAAGAAG
CTTGGCTTCAAACATCCAGTTATTGGAGTCCATGTCAGACGCACAGACAAAGTGGGAACAGAAGCTGCCTTCCATCCCATTGAAGAGTAC
ATGGTGCATGTTGAAGAACATTTTCAGCTTCTTGCACGCAGAATGCAAGTGGACAAAAAAAGAGTGTATTTGGCCACAGATGACCCTTCT
TTATTAAAGGAGGCAAAAACAAAGTACCCCAATTATGAATTTATTAGTGATAACTCTATTTCCTGGTCAGCTGGACTGCACAATCGATAC
ACAGAAAATTCACTTCGTGGAGTGATCCTGGATATACATTTTCTCTCTCAGGCAGACTTCCTAGTGTGTACTTTTTCATCCCAGGTGTCA
ACAGGAAATTGGGAAGGACGGGCCTATATCCCTCCTACAAAGTTCGAGAGAAGATAGAAACGGTCAAGTACCCCACATATCCTGAGGCTG
AGAAATAAAGCTCAGATGGAAGAGATAAACGACCAAACTCAGTTCGACCAAACTCAGTTCAAACCATTTCAGCCAAACTGTAGATGAAGA
GGGCTCTGATCTAACAAAATAAGGTTATATGAGTAGATACTCTCAGCACCAAGAGCAGCTGGGAACTGACATAGGCTTCAATTGGTGGAA
TTCCTCTTTAACAAGGGCTGCAATGCCCTCATACCCATGCACAGTACAATAATGTACTCACATATAACATGCAAACAGGTTGTTTTCTAC
TTTGCCCCTTTCAGTATGTCCCCATAAGACAAACACTGCCATATTGTGTAATTTAAGTGACACAGACATTTTGTGTGAGACTTAAAACAT
GGTGCCTATATCTGAGAGACCTGTGTGAACTATTGAGAAGATCGGAACAGCTCCTTACTCTGAGGAAGTTGATTCTTATTTGATGGTGGT
ATTGTGACCACTGAATTCACTCCAGTCAACAGATTCAGAATGAGAATGGACGTTTGGTTTTTTTTTGTTTTTGTTTTTGTTTTTTCCTTT
ATAAGGTTGTCTGTTTTTTTTTTTTTAAATAATTGCATCAGTTCATTGACCTCATCATTAATAAGTGAAGAATACATCAGAAAATAAAAT
ATTCACTCTCCATTAGAAAATTTTGTAAAACAATGCCATGAACAAATTCTTTAGTACTCAATGTTTCTGGACATTCTCTTTGATAACAAA
AAATAAATTTTAAAAAGGAATGACACCAATATTAACTTTTTACTAGAAGAATATGGAATCATGGTTAATAATGATGCTGTGGTTAGAAAT
GTATATCACAAATATTTCCATCCTAAAGAAGCTCTAGTTTCCAGTGGAGTCTTGAACAGGGAAATTAGCCGAGCTGCAGGAAAGGCTGTG
CCTGGGATCATTGATGAGGAAAGCAGTGGAAACAATGCCCAGGCTCTCACCTTTGTGTATCCTTTTGGTGCCACATTGAGTGTCATGAAA
CCAGCAGTGGCGGTTCTGTCTACAGGTTCTGTCTGCTTCCCACTTAACAGACCCATTTTGGCTTTCTATCACTCAAAGAACCAAGGTGGG
AAGCTGGCAGTGCTTGGTTCATGTCACATGTTCAGTGATCAATATTTGGACAAAGAAGAAAACAGCAAAATCATGGATGTTGTTTTCCAG
TGGCTCACGACAGGAGACATCCACCTAAACCAGATTGATGCTGAGGACCCAGAGATTTCTGACTACATGATGCTGCCCTACACAGCCACC
CTATCAAAGCGGAATCGAGAGTGTCTCCAGGAGAGTGATGAGATCCCAAGGGACTTTACCACCCTCTTCGACCTGTCCATCTTCCAGCTG
GATACCACCTCCTTCCACAGCGTCATCGAGGCTCACGAGCAGCTAAATGTGAAACATGAACCACTCCAGCTCATCCAGCCTCAGTTTGAG
ACGCCGCTGCCAACCCTTCAGCCTGCGGTTTTTCCTCCCAGTTTCCGGGAGTTACCACCTCCTCCTCTGGAGCTATTTGATTTAGATGAA
ACGTTCTCCTCTGAGAAGGCACGGCTGGCTCAGATTACCAATAAGTGTACTGAAGAAGACCTGGAATTTTATGTCAGGAAGTGTGGTGAT
ATTCTTGGAGTAACCAGTAAACTACCAAAGGACCAACAGGATGCCAAACATATCCTTGAGCACGTCTTCTTCCAAGTGGTGGAGTTCAAG
AAATTGAACCAGGAACATGACATCGATACAAGTGAAACAGCATTCCAGAACAATTTCTGAAGACCATGCCTCTTGAAGCTTTTTCTGCCT
CCTGATTCTCTCTTTGTAAACTATTTTCAAATTGTTTTTCAACTCCTTATCAAAATTGTTTATACACTCTTTCCTCCATGAGCTCTGGAA
GGTATATGCATCTTCTGTAATACTCAGATAGGTATAAGATTTTTCACAAAATCCTTATGTAAGATACATTCCATTTTTAAAAATTAAATG

>31848_31848_2_FUT8-IFT52_FUT8_chr14_66209024_ENST00000358307_IFT52_chr20_42232476_ENST00000373039_length(amino acids)=461AA_BP=
MDKFRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFL
LDLGHHERILMAITVSLVNNKRKIVVLAQPTTVKRKRITPYKSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKK
LVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHP
RPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEH
FQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVSTGNWEGR

--------------------------------------------------------------
>31848_31848_3_FUT8-IFT52_FUT8_chr14_66209024_ENST00000394586_IFT52_chr20_42232476_ENST00000373030_length(transcript)=4688nt_BP=3345nt
CGTTTAGTACAGAAATCTCATGGGAGAGAGCATCCATGCATTTACAAATTGTTATTGAATTATTTTATTGAATGATGACACCCAAACTGA
GCTAGAACATAATTCTGGCTCTGCTAGTACATCTTCTGTGTGATCTTGGACAAGTCACTCTACTTTCCTTTCAATTTTCTTTTCTCACAG
GGAGATAATCATAAAAACGACTGTAAAGTACAGCACTTCATAGAGTGCTTTTTGTTTAAAGAGCTGACAATAAATACGAGTCTCAAGGTC
TAGGAAAGCCTCCCTCACAACCTGAGCTGCTTGAGGACAAGGGATTTTCTTTTGAATCAGCAGTACCTTATTTGTGTATCTGTGATAGAG
TTCCTGGTACATAAGAAGGTCTCAATAAATATGTGAATTTATGAATATTAGGCAGATTGCAACCTTGACAGGCCACTGCCTCTTAAATCT
CCTTTCTGTGATCTTTTAATATTTAACATCTAAAAGGCCGCCGCTACTTGCTTTGGGATAAGTATCCCCGGTATGTACTTTAAAATGCCC
AAGCCTAGAGAAATGATTCTTGTCTTAAGGGCACCATTTCGCTCTCCCACCGTAAAGCGCCCCAGGCTTGGGATCTGGGTCCCAAGGCTA
CAGGGAAGAGTTTGGAACGGGAAGCTCATCTTCCGGCCCTCTGATTGGCCGGCTCGCACTCCACTCACGCGGCGCGCAGCTCTGATTGGC
CTCGGCGGCACCCCTCGTCCCGCGACTACTTTGTGTGCTGGGGCGGCGCGCTCCGGTCCTCCCGCTCAGCTGGCGGTCTGGGCTGCTCTG
GGGCAGCCCTTCGGTCCACTGCTCTGCATCGCGGGCGCCGGGAATTTTCCGAGTCCGAGCGGCATGTAGAGCGCATGAAGTACAGGACAA
TAAAGCTTCCTACACATATCACCAGGAGGATCTCTTTGAAAGATTCACTGCAGGACTACCAGAGAGAATAATTTGTCTGAAGCATCATGT
GTTGAAACAACAGAAGTCTATTCACCTGTGCACTAACTAGAAACAGAGTTACAATGTTTTCAATTCTTTGAGCTCCAGGACTCCAGGGAA
GTGAGTTGAAAATCTGAAAATGCGGCCATGGACTGGTTCCTGGCGTTGGATTATGCTCATTCTTTTTGCCTGGGGGACCTTGCTGTTTTA
TATAGGTGGTCACTTGGTACGAGATAATGACCATCCTGATCACTCTAGCCGAGAACTGTCCAAGATTCTGGCAAAGCTTGAACGCTTAAA
ACAACAGAATGAAGACTTGAGGCGAATGGCCGAATCTCTCCGGATACCAGAAGGCCCTATTGATCAGGGGCCAGCTATAGGAAGAGTACG
CGTTTTAGAAGAGCAGCTTGTTAAGGCCAAAGAACAGATTGAAAATTACAAGAAACAGACCAGAAATGGTCTGGGGAAGGATCATGAAAT
CCTGAGGAGGAGGATTGAAAATGGAGCTAAAGAGCTCTGGTTTTTCCTACAGAGTGAATTGAAGAAATTAAAGAACTTAGAAGGAAATGA
ACTCCAAAGACATGCAGATGAATTTCTTTTGGATTTAGGACATCATGAAAGGTCTATAATGACGGATCTATACTACCTCAGTCAGACAGA
TGGAGCAGGTGATTGGCGGGAAAAAGAGGCCAAAGATCTGACAGAACTGGTTCAGCGGAGAATAACATATCTTCAGAATCCCAAGGACTG
CAGCAAAGCCAAAAAGCTGGTGTGTAATATCAACAAAGGCTGTGGCTATGGCTGTCAGCTCCATCATGTGGTCTACTGCTTCATGATTGC
ATATGGCACCCAGCGAACACTCATCTTGGAATCTCAGAATTGGCGCTATGCTACTGGTGGATGGGAGACTGTATTTAGGCCTGTAAGTGA
GACATGCACAGACAGATCTGGCATCTCCACTGGACACTGGTCAGGTGAAGTGAAGGACAAAAATGTTCAAGTGGTCGAGCTTCCCATTGT
AGACAGTCTTCATCCCCGTCCTCCATATTTACCCTTGGCTGTACCAGAAGACCTCGCAGATCGACTTGTACGAGTGCATGGTGACCCTGC
AGTGTGGTGGGTGTCTCAGTTTGTCAAATACTTGATCCGCCCACAGCCTTGGCTAGAAAAAGAAATAGAAGAAGCCACCAAGAAGCTTGG
CTTCAAACATCCAGTTATTGGAGTCCATGTCAGACGCACAGACAAAGTGGGAACAGAAGCTGCCTTCCATCCCATTGAAGAGTACATGGT
GCATGTTGAAGAACATTTTCAGCTTCTTGCACGCAGAATGCAAGTGGACAAAAAAAGAGTGTATTTGGCCACAGATGACCCTTCTTTATT
AAAGGAGGCAAAAACAAAGTACCCCAATTATGAATTTATTAGTGATAACTCTATTTCCTGGTCAGCTGGACTGCACAATCGATACACAGA
AAATTCACTTCGTGGAGTGATCCTGGATATACATTTTCTCTCTCAGGCAGACTTCCTAGTGTGTACTTTTTCATCCCAGGTGTCAACAGG
AAATTGGGAAGGACGGGCCTATATCCCTCCTACAAAGTTCGAGAGAAGATAGAAACGGTCAAGTACCCCACATATCCTGAGGCTGAGAAA
TAAAGCTCAGATGGAAGAGATAAACGACCAAACTCAGTTCGACCAAACTCAGTTCAAACCATTTCAGCCAAACTGTAGATGAAGAGGGCT
CTGATCTAACAAAATAAGGTTATATGAGTAGATACTCTCAGCACCAAGAGCAGCTGGGAACTGACATAGGCTTCAATTGGTGGAATTCCT
CTTTAACAAGGGCTGCAATGCCCTCATACCCATGCACAGTACAATAATGTACTCACATATAACATGCAAACAGGTTGTTTTCTACTTTGC
CCCTTTCAGTATGTCCCCATAAGACAAACACTGCCATATTGTGTAATTTAAGTGACACAGACATTTTGTGTGAGACTTAAAACATGGTGC
CTATATCTGAGAGACCTGTGTGAACTATTGAGAAGATCGGAACAGCTCCTTACTCTGAGGAAGTTGATTCTTATTTGATGGTGGTATTGT
GACCACTGAATTCACTCCAGTCAACAGATTCAGAATGAGAATGGACGTTTGGTTTTTTTTTGTTTTTGTTTTTGTTTTTTCCTTTATAAG
GTTGTCTGTTTTTTTTTTTTTAAATAATTGCATCAGTTCATTGACCTCATCATTAATAAGTGAAGAATACATCAGAAAATAAAATATTCA
CTCTCCATTAGAAAATTTTGTAAAACAATGCCATGAACAAATTCTTTAGTACTCAATGTTTCTGGACATTCTCTTTGATAACAAAAAATA
AATTTTAAAAAGGAATGACACCAATATTAACTTTTTACTAGAAGAATATGGAATCATGGTTAATAATGATGCTGTGGTTAGAAATGTATA
TCACAAATATTTCCATCCTAAAGAAGCTCTAGTTTCCAGTGGAGTCTTGAACAGGGAAATTAGCCGAGCTGCAGGAAAGGCTGTGCCTGG
GATCATTGATGAGGAAAGCAGTGGAAACAATGCCCAGGCTCTCACCTTTGTGTATCCTTTTGGTGCCACATTGAGTGTCATGAAACCAGC
AGTGGCGGTTCTGTCTACAGGTTCTGTCTGCTTCCCACTTAACAGACCCATTTTGGCTTTCTATCACTCAAAGAACCAAGGTGGGAAGCT
GGCAGTGCTTGGTTCATGTCACATGTTCAGTGATCAATATTTGGACAAAGAAGAAAACAGCAAAATCATGGATGTTGTTTTCCAGTGGCT
CACGACAGGAGACATCCACCTAAACCAGATTGATGCTGAGGACCCAGAGATTTCTGACTACATGATGCTGCCCTACACAGCCACCCTATC
AAAGCGGAATCGAGAGTGTCTCCAGGAGAGTGATGAGATCCCAAGGGACTTTACCACCCTCTTCGACCTGTCCATCTTCCAGCTGGATAC
CACCTCCTTCCACAGCGTCATCGAGGCTCACGAGCAGCTAAATGTGAAACATGAACCACTCCAGCTCATCCAGCCTCAGTTTGAGACGCC
GCTGCCAACCCTTCAGCCTGCGGTTTTTCCTCCCAGTTTCCGGGAGTTACCACCTCCTCCTCTGGAGCTATTTGATTTAGATGAAACGTT
CTCCTCTGAGAAGGCACGGCTGGCTCAGATTACCAATAAGTGTACTGAAGAAGACCTGGAATTTTATGTCAGGAAGTGTGGTGATATTCT
TGGAGTAACCAGTAAACTACCAAAGGACCAACAGGATGCCAAACATATCCTTGAGCACGTCTTCTTCCAAGTGGTGGAGTTCAAGAAATT
GAACCAGGAACATGACATCGATACAAGTGAAACAGCATTCCAGAACAATTTCTGAAGACCATGCCTCTTGAAGCTTTTTCTGCCTCCTGA
TTCTCTCTTTGTAAACTATTTTCAAATTGTTTTTCAACTCCTTATCAAAATTGTTTATACACTCTTTCCTCCATGAGCTCTGGAAGGTAT
ATGCATCTTCTGTAATACTCAGATAGGTATAAGATTTTTCACAAAATCCTTATGTAAGATACATTCCATTTTTAAAAATTAAATGTATGG
TTGCATCTGTCTTTTTATACCCTATGAAACAGTCTTGATTTTTTTTTCTCAACCCCAGTTCTGGATTTGAGTCTTTTATCAAAGACATAA

>31848_31848_3_FUT8-IFT52_FUT8_chr14_66209024_ENST00000394586_IFT52_chr20_42232476_ENST00000373030_length(amino acids)=492AA_BP=
MKMRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEE
QLVKAKEQIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGD
WREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTD
RSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHP
VIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLR

--------------------------------------------------------------
>31848_31848_4_FUT8-IFT52_FUT8_chr14_66209024_ENST00000394586_IFT52_chr20_42232476_ENST00000373039_length(transcript)=4614nt_BP=3345nt
CGTTTAGTACAGAAATCTCATGGGAGAGAGCATCCATGCATTTACAAATTGTTATTGAATTATTTTATTGAATGATGACACCCAAACTGA
GCTAGAACATAATTCTGGCTCTGCTAGTACATCTTCTGTGTGATCTTGGACAAGTCACTCTACTTTCCTTTCAATTTTCTTTTCTCACAG
GGAGATAATCATAAAAACGACTGTAAAGTACAGCACTTCATAGAGTGCTTTTTGTTTAAAGAGCTGACAATAAATACGAGTCTCAAGGTC
TAGGAAAGCCTCCCTCACAACCTGAGCTGCTTGAGGACAAGGGATTTTCTTTTGAATCAGCAGTACCTTATTTGTGTATCTGTGATAGAG
TTCCTGGTACATAAGAAGGTCTCAATAAATATGTGAATTTATGAATATTAGGCAGATTGCAACCTTGACAGGCCACTGCCTCTTAAATCT
CCTTTCTGTGATCTTTTAATATTTAACATCTAAAAGGCCGCCGCTACTTGCTTTGGGATAAGTATCCCCGGTATGTACTTTAAAATGCCC
AAGCCTAGAGAAATGATTCTTGTCTTAAGGGCACCATTTCGCTCTCCCACCGTAAAGCGCCCCAGGCTTGGGATCTGGGTCCCAAGGCTA
CAGGGAAGAGTTTGGAACGGGAAGCTCATCTTCCGGCCCTCTGATTGGCCGGCTCGCACTCCACTCACGCGGCGCGCAGCTCTGATTGGC
CTCGGCGGCACCCCTCGTCCCGCGACTACTTTGTGTGCTGGGGCGGCGCGCTCCGGTCCTCCCGCTCAGCTGGCGGTCTGGGCTGCTCTG
GGGCAGCCCTTCGGTCCACTGCTCTGCATCGCGGGCGCCGGGAATTTTCCGAGTCCGAGCGGCATGTAGAGCGCATGAAGTACAGGACAA
TAAAGCTTCCTACACATATCACCAGGAGGATCTCTTTGAAAGATTCACTGCAGGACTACCAGAGAGAATAATTTGTCTGAAGCATCATGT
GTTGAAACAACAGAAGTCTATTCACCTGTGCACTAACTAGAAACAGAGTTACAATGTTTTCAATTCTTTGAGCTCCAGGACTCCAGGGAA
GTGAGTTGAAAATCTGAAAATGCGGCCATGGACTGGTTCCTGGCGTTGGATTATGCTCATTCTTTTTGCCTGGGGGACCTTGCTGTTTTA
TATAGGTGGTCACTTGGTACGAGATAATGACCATCCTGATCACTCTAGCCGAGAACTGTCCAAGATTCTGGCAAAGCTTGAACGCTTAAA
ACAACAGAATGAAGACTTGAGGCGAATGGCCGAATCTCTCCGGATACCAGAAGGCCCTATTGATCAGGGGCCAGCTATAGGAAGAGTACG
CGTTTTAGAAGAGCAGCTTGTTAAGGCCAAAGAACAGATTGAAAATTACAAGAAACAGACCAGAAATGGTCTGGGGAAGGATCATGAAAT
CCTGAGGAGGAGGATTGAAAATGGAGCTAAAGAGCTCTGGTTTTTCCTACAGAGTGAATTGAAGAAATTAAAGAACTTAGAAGGAAATGA
ACTCCAAAGACATGCAGATGAATTTCTTTTGGATTTAGGACATCATGAAAGGTCTATAATGACGGATCTATACTACCTCAGTCAGACAGA
TGGAGCAGGTGATTGGCGGGAAAAAGAGGCCAAAGATCTGACAGAACTGGTTCAGCGGAGAATAACATATCTTCAGAATCCCAAGGACTG
CAGCAAAGCCAAAAAGCTGGTGTGTAATATCAACAAAGGCTGTGGCTATGGCTGTCAGCTCCATCATGTGGTCTACTGCTTCATGATTGC
ATATGGCACCCAGCGAACACTCATCTTGGAATCTCAGAATTGGCGCTATGCTACTGGTGGATGGGAGACTGTATTTAGGCCTGTAAGTGA
GACATGCACAGACAGATCTGGCATCTCCACTGGACACTGGTCAGGTGAAGTGAAGGACAAAAATGTTCAAGTGGTCGAGCTTCCCATTGT
AGACAGTCTTCATCCCCGTCCTCCATATTTACCCTTGGCTGTACCAGAAGACCTCGCAGATCGACTTGTACGAGTGCATGGTGACCCTGC
AGTGTGGTGGGTGTCTCAGTTTGTCAAATACTTGATCCGCCCACAGCCTTGGCTAGAAAAAGAAATAGAAGAAGCCACCAAGAAGCTTGG
CTTCAAACATCCAGTTATTGGAGTCCATGTCAGACGCACAGACAAAGTGGGAACAGAAGCTGCCTTCCATCCCATTGAAGAGTACATGGT
GCATGTTGAAGAACATTTTCAGCTTCTTGCACGCAGAATGCAAGTGGACAAAAAAAGAGTGTATTTGGCCACAGATGACCCTTCTTTATT
AAAGGAGGCAAAAACAAAGTACCCCAATTATGAATTTATTAGTGATAACTCTATTTCCTGGTCAGCTGGACTGCACAATCGATACACAGA
AAATTCACTTCGTGGAGTGATCCTGGATATACATTTTCTCTCTCAGGCAGACTTCCTAGTGTGTACTTTTTCATCCCAGGTGTCAACAGG
AAATTGGGAAGGACGGGCCTATATCCCTCCTACAAAGTTCGAGAGAAGATAGAAACGGTCAAGTACCCCACATATCCTGAGGCTGAGAAA
TAAAGCTCAGATGGAAGAGATAAACGACCAAACTCAGTTCGACCAAACTCAGTTCAAACCATTTCAGCCAAACTGTAGATGAAGAGGGCT
CTGATCTAACAAAATAAGGTTATATGAGTAGATACTCTCAGCACCAAGAGCAGCTGGGAACTGACATAGGCTTCAATTGGTGGAATTCCT
CTTTAACAAGGGCTGCAATGCCCTCATACCCATGCACAGTACAATAATGTACTCACATATAACATGCAAACAGGTTGTTTTCTACTTTGC
CCCTTTCAGTATGTCCCCATAAGACAAACACTGCCATATTGTGTAATTTAAGTGACACAGACATTTTGTGTGAGACTTAAAACATGGTGC
CTATATCTGAGAGACCTGTGTGAACTATTGAGAAGATCGGAACAGCTCCTTACTCTGAGGAAGTTGATTCTTATTTGATGGTGGTATTGT
GACCACTGAATTCACTCCAGTCAACAGATTCAGAATGAGAATGGACGTTTGGTTTTTTTTTGTTTTTGTTTTTGTTTTTTCCTTTATAAG
GTTGTCTGTTTTTTTTTTTTTAAATAATTGCATCAGTTCATTGACCTCATCATTAATAAGTGAAGAATACATCAGAAAATAAAATATTCA
CTCTCCATTAGAAAATTTTGTAAAACAATGCCATGAACAAATTCTTTAGTACTCAATGTTTCTGGACATTCTCTTTGATAACAAAAAATA
AATTTTAAAAAGGAATGACACCAATATTAACTTTTTACTAGAAGAATATGGAATCATGGTTAATAATGATGCTGTGGTTAGAAATGTATA
TCACAAATATTTCCATCCTAAAGAAGCTCTAGTTTCCAGTGGAGTCTTGAACAGGGAAATTAGCCGAGCTGCAGGAAAGGCTGTGCCTGG
GATCATTGATGAGGAAAGCAGTGGAAACAATGCCCAGGCTCTCACCTTTGTGTATCCTTTTGGTGCCACATTGAGTGTCATGAAACCAGC
AGTGGCGGTTCTGTCTACAGGTTCTGTCTGCTTCCCACTTAACAGACCCATTTTGGCTTTCTATCACTCAAAGAACCAAGGTGGGAAGCT
GGCAGTGCTTGGTTCATGTCACATGTTCAGTGATCAATATTTGGACAAAGAAGAAAACAGCAAAATCATGGATGTTGTTTTCCAGTGGCT
CACGACAGGAGACATCCACCTAAACCAGATTGATGCTGAGGACCCAGAGATTTCTGACTACATGATGCTGCCCTACACAGCCACCCTATC
AAAGCGGAATCGAGAGTGTCTCCAGGAGAGTGATGAGATCCCAAGGGACTTTACCACCCTCTTCGACCTGTCCATCTTCCAGCTGGATAC
CACCTCCTTCCACAGCGTCATCGAGGCTCACGAGCAGCTAAATGTGAAACATGAACCACTCCAGCTCATCCAGCCTCAGTTTGAGACGCC
GCTGCCAACCCTTCAGCCTGCGGTTTTTCCTCCCAGTTTCCGGGAGTTACCACCTCCTCCTCTGGAGCTATTTGATTTAGATGAAACGTT
CTCCTCTGAGAAGGCACGGCTGGCTCAGATTACCAATAAGTGTACTGAAGAAGACCTGGAATTTTATGTCAGGAAGTGTGGTGATATTCT
TGGAGTAACCAGTAAACTACCAAAGGACCAACAGGATGCCAAACATATCCTTGAGCACGTCTTCTTCCAAGTGGTGGAGTTCAAGAAATT
GAACCAGGAACATGACATCGATACAAGTGAAACAGCATTCCAGAACAATTTCTGAAGACCATGCCTCTTGAAGCTTTTTCTGCCTCCTGA
TTCTCTCTTTGTAAACTATTTTCAAATTGTTTTTCAACTCCTTATCAAAATTGTTTATACACTCTTTCCTCCATGAGCTCTGGAAGGTAT
ATGCATCTTCTGTAATACTCAGATAGGTATAAGATTTTTCACAAAATCCTTATGTAAGATACATTCCATTTTTAAAAATTAAATGTATGG

>31848_31848_4_FUT8-IFT52_FUT8_chr14_66209024_ENST00000394586_IFT52_chr20_42232476_ENST00000373039_length(amino acids)=492AA_BP=
MKMRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDLRRMAESLRIPEGPIDQGPAIGRVRVLEE
QLVKAKEQIENYKKQTRNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGD
WREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTD
RSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHP
VIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FUT8-IFT52


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FUT8-IFT52


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FUT8-IFT52


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource