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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GAB2-ALG8 (FusionGDB2 ID:32025)

Fusion Gene Summary for GAB2-ALG8

check button Fusion gene summary
Fusion gene informationFusion gene name: GAB2-ALG8
Fusion gene ID: 32025
HgeneTgene
Gene symbol

GAB2

ALG8

Gene ID

9846

79053

Gene nameGRB2 associated binding protein 2ALG8 alpha-1,3-glucosyltransferase
Synonyms-CDG1H|PCLD3
Cytomap

11q14.1

11q14.1

Type of geneprotein-codingprotein-coding
DescriptionGRB2-associated-binding protein 2Grb2-associated binder 2growth factor receptor bound protein 2-associated protein 2pp100probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferaseHUSSY-02asparagine-linked glycosylation 8 alpha-13-glucosyltransferase-like proteinasparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)asp
Modification date2020032720200313
UniProtAcc

Q9UQC2

Q9BVK2

Ensembl transtripts involved in fusion geneENST00000361507, ENST00000526030, 
ENST00000340149, 		ENST00000532552, 
ENST00000299626, ENST00000376156, 
Fusion gene scores* DoF score25 X 12 X 7=21006 X 6 X 8=288
# samples 2710
** MAII scorelog2(27/2100*10)=-2.95935801550265
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/288*10)=-1.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GAB2 [Title/Abstract] AND ALG8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGAB2(78128692)-ALG8(77838482), # samples:2
GAB2(78128692)-ALG8(77820627), # samples:2
Anticipated loss of major functional domain due to fusion event.GAB2-ALG8 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
GAB2-ALG8 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
GAB2-ALG8 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGAB2

GO:0008284

positive regulation of cell proliferation

19172738


check buttonFusion gene breakpoints across GAB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ALG8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1EN-01AGAB2chr11

78128692

-ALG8chr11

77838482

-
ChimerDB4BRCATCGA-BH-A1ENGAB2chr11

78128691

-ALG8chr11

77838482

-
ChimerDB4LUADTCGA-38-4630-01AGAB2chr11

78128692

-ALG8chr11

77817992

-
ChimerDB4LUADTCGA-38-4630-01AGAB2chr11

78128692

-ALG8chr11

77820627

-
ChimerDB4LUADTCGA-38-4630-01AGAB2chr11

78128692

-ALG8chr11

77825438

-


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Fusion Gene ORF analysis for GAB2-ALG8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000361507ENST00000532552GAB2chr11

78128692

-ALG8chr11

77820627

-
5CDS-intronENST00000361507ENST00000532552GAB2chr11

78128692

-ALG8chr11

77838482

-
5CDS-intronENST00000361507ENST00000532552GAB2chr11

78128691

-ALG8chr11

77838482

-
5CDS-intronENST00000361507ENST00000532552GAB2chr11

78128692

-ALG8chr11

77817992

-
5CDS-intronENST00000361507ENST00000532552GAB2chr11

78128692

-ALG8chr11

77825438

-
5UTR-3CDSENST00000526030ENST00000299626GAB2chr11

78128692

-ALG8chr11

77838482

-
5UTR-3CDSENST00000526030ENST00000299626GAB2chr11

78128691

-ALG8chr11

77838482

-
5UTR-3CDSENST00000526030ENST00000299626GAB2chr11

78128692

-ALG8chr11

77817992

-
5UTR-3CDSENST00000526030ENST00000299626GAB2chr11

78128692

-ALG8chr11

77820627

-
5UTR-3CDSENST00000526030ENST00000299626GAB2chr11

78128692

-ALG8chr11

77825438

-
5UTR-3CDSENST00000526030ENST00000376156GAB2chr11

78128692

-ALG8chr11

77838482

-
5UTR-3CDSENST00000526030ENST00000376156GAB2chr11

78128691

-ALG8chr11

77838482

-
5UTR-3CDSENST00000526030ENST00000376156GAB2chr11

78128692

-ALG8chr11

77817992

-
5UTR-3CDSENST00000526030ENST00000376156GAB2chr11

78128692

-ALG8chr11

77820627

-
5UTR-3CDSENST00000526030ENST00000376156GAB2chr11

78128692

-ALG8chr11

77825438

-
5UTR-5UTRENST00000526030ENST00000532552GAB2chr11

78128692

-ALG8chr11

77820627

-
5UTR-intronENST00000526030ENST00000532552GAB2chr11

78128692

-ALG8chr11

77838482

-
5UTR-intronENST00000526030ENST00000532552GAB2chr11

78128691

-ALG8chr11

77838482

-
5UTR-intronENST00000526030ENST00000532552GAB2chr11

78128692

-ALG8chr11

77817992

-
5UTR-intronENST00000526030ENST00000532552GAB2chr11

78128692

-ALG8chr11

77825438

-
Frame-shiftENST00000361507ENST00000299626GAB2chr11

78128692

-ALG8chr11

77838482

-
Frame-shiftENST00000361507ENST00000299626GAB2chr11

78128691

-ALG8chr11

77838482

-
Frame-shiftENST00000361507ENST00000299626GAB2chr11

78128692

-ALG8chr11

77820627

-
Frame-shiftENST00000361507ENST00000376156GAB2chr11

78128692

-ALG8chr11

77820627

-
In-frameENST00000361507ENST00000299626GAB2chr11

78128692

-ALG8chr11

77817992

-
In-frameENST00000361507ENST00000299626GAB2chr11

78128692

-ALG8chr11

77825438

-
In-frameENST00000361507ENST00000376156GAB2chr11

78128692

-ALG8chr11

77838482

-
In-frameENST00000361507ENST00000376156GAB2chr11

78128691

-ALG8chr11

77838482

-
In-frameENST00000361507ENST00000376156GAB2chr11

78128692

-ALG8chr11

77817992

-
In-frameENST00000361507ENST00000376156GAB2chr11

78128692

-ALG8chr11

77825438

-
intron-3CDSENST00000340149ENST00000299626GAB2chr11

78128692

-ALG8chr11

77838482

-
intron-3CDSENST00000340149ENST00000299626GAB2chr11

78128691

-ALG8chr11

77838482

-
intron-3CDSENST00000340149ENST00000299626GAB2chr11

78128692

-ALG8chr11

77817992

-
intron-3CDSENST00000340149ENST00000299626GAB2chr11

78128692

-ALG8chr11

77820627

-
intron-3CDSENST00000340149ENST00000299626GAB2chr11

78128692

-ALG8chr11

77825438

-
intron-3CDSENST00000340149ENST00000376156GAB2chr11

78128692

-ALG8chr11

77838482

-
intron-3CDSENST00000340149ENST00000376156GAB2chr11

78128691

-ALG8chr11

77838482

-
intron-3CDSENST00000340149ENST00000376156GAB2chr11

78128692

-ALG8chr11

77817992

-
intron-3CDSENST00000340149ENST00000376156GAB2chr11

78128692

-ALG8chr11

77820627

-
intron-3CDSENST00000340149ENST00000376156GAB2chr11

78128692

-ALG8chr11

77825438

-
intron-5UTRENST00000340149ENST00000532552GAB2chr11

78128692

-ALG8chr11

77820627

-
intron-intronENST00000340149ENST00000532552GAB2chr11

78128692

-ALG8chr11

77838482

-
intron-intronENST00000340149ENST00000532552GAB2chr11

78128691

-ALG8chr11

77838482

-
intron-intronENST00000340149ENST00000532552GAB2chr11

78128692

-ALG8chr11

77817992

-
intron-intronENST00000340149ENST00000532552GAB2chr11

78128692

-ALG8chr11

77825438

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361507GAB2chr1178128692-ENST00000376156ALG8chr1177838482-17391612131469418
ENST00000361507GAB2chr1178128691-ENST00000376156ALG8chr1177838482-17391612131469418
ENST00000361507GAB2chr1178128692-ENST00000299626ALG8chr1177817992-72616120703227
ENST00000361507GAB2chr1178128692-ENST00000376156ALG8chr1177817992-79616120526168
ENST00000361507GAB2chr1178128692-ENST00000299626ALG8chr1177825438-1218161201195391
ENST00000361507GAB2chr1178128692-ENST00000376156ALG8chr1177825438-1288161201018332

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361507ENST00000376156GAB2chr1178128692-ALG8chr1177838482-0.0248982140.9751018
ENST00000361507ENST00000376156GAB2chr1178128691-ALG8chr1177838482-0.0248982140.9751018
ENST00000361507ENST00000299626GAB2chr1178128692-ALG8chr1177817992-0.191516370.80848366
ENST00000361507ENST00000376156GAB2chr1178128692-ALG8chr1177817992-0.355259330.6447407
ENST00000361507ENST00000299626GAB2chr1178128692-ALG8chr1177825438-0.089494650.91050535
ENST00000361507ENST00000376156GAB2chr1178128692-ALG8chr1177825438-0.143689420.8563106

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Fusion Genomic Features for GAB2-ALG8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GAB2-ALG8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:78128692/chr11:77838482)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GAB2

Q9UQC2

ALG8

Q9BVK2

FUNCTION: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. {ECO:0000269|PubMed:15750601, ECO:0000269|PubMed:19172738}.FUNCTION: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol before it is transferred to the nascent peptide (By similarity). Required for PKD1/Polycystin-1 maturation and localization to the plasma membrane of the primary cilia (By similarity). {ECO:0000250|UniProtKB:P40351, ECO:0000250|UniProtKB:Q6P8H8}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013103_12231527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013143_16331527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013188_20831527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013238_25831527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013334_35431527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013368_38831527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013389_40931527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013427_44931527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013461_48131527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000299626013488_50831527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014103_12231516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014143_16331516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014188_20831516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014238_25831516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014334_35431516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014368_38831516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014389_40931516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014427_44931516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014461_48131516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST00000376156014488_50831516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813368_388346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813389_409346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813427_449346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813461_481346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813488_508346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814368_388346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814389_409346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814427_449346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814461_481346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814488_508346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413188_208182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413238_258182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413334_354182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413368_388182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413389_409182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413427_449182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413461_481182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413488_508182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414188_208182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414238_258182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414334_354182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414368_388182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414389_409182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414427_449182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414461_481182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414488_508182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013103_12231527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013143_16331527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013188_20831527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013238_25831527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013334_35431527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013368_38831527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013389_40931527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013427_44931527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013461_48131527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000299626013488_50831527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014103_12231516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014143_16331516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014188_20831516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014238_25831516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014334_35431516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014368_38831516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014389_40931516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014427_44931516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014461_48131516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST00000376156014488_50831516.6666666666666TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGAB2chr11:78128691chr11:77838482ENST00000340149-1106_1170639.0DomainPH
HgeneGAB2chr11:78128691chr11:77838482ENST00000361507-1106_11725677.0DomainPH
HgeneGAB2chr11:78128692chr11:77817992ENST00000340149-1106_1170639.0DomainPH
HgeneGAB2chr11:78128692chr11:77817992ENST00000361507-1106_11725677.0DomainPH
HgeneGAB2chr11:78128692chr11:77825438ENST00000340149-1106_1170639.0DomainPH
HgeneGAB2chr11:78128692chr11:77825438ENST00000361507-1106_11725677.0DomainPH
HgeneGAB2chr11:78128692chr11:77838482ENST00000340149-1106_1170639.0DomainPH
HgeneGAB2chr11:78128692chr11:77838482ENST00000361507-1106_11725677.0DomainPH
HgeneGAB2chr11:78128691chr11:77838482ENST00000340149-110351_3580639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128691chr11:77838482ENST00000340149-110510_5190639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128691chr11:77838482ENST00000361507-110351_35825677.0MotifNote=SH3-binding
HgeneGAB2chr11:78128691chr11:77838482ENST00000361507-110510_51925677.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77817992ENST00000340149-110351_3580639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77817992ENST00000340149-110510_5190639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77817992ENST00000361507-110351_35825677.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77817992ENST00000361507-110510_51925677.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77825438ENST00000340149-110351_3580639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77825438ENST00000340149-110510_5190639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77825438ENST00000361507-110351_35825677.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77825438ENST00000361507-110510_51925677.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77838482ENST00000340149-110351_3580639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77838482ENST00000340149-110510_5190639.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77838482ENST00000361507-110351_35825677.0MotifNote=SH3-binding
HgeneGAB2chr11:78128692chr11:77838482ENST00000361507-110510_51925677.0MotifNote=SH3-binding
TgeneALG8chr11:78128691chr11:77838482ENST000002996260134_2431527.0TransmembraneHelical
TgeneALG8chr11:78128691chr11:77838482ENST000003761560144_2431516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813103_122346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813143_163346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813188_208346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813238_258346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000299626813334_354346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST000002996268134_24346527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814103_122346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814143_163346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814188_208346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814238_258346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST00000376156814334_354346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77817992ENST000003761568144_24346516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413103_122182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000299626413143_163182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST000002996264134_24182527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414103_122182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST00000376156414143_163182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77825438ENST000003761564144_24182516.6666666666666TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST000002996260134_2431527.0TransmembraneHelical
TgeneALG8chr11:78128692chr11:77838482ENST000003761560144_2431516.6666666666666TransmembraneHelical


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Fusion Gene Sequence for GAB2-ALG8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>32025_32025_1_GAB2-ALG8_GAB2_chr11_78128691_ENST00000361507_ALG8_chr11_77838482_ENST00000376156_length(transcript)=1739nt_BP=161nt
GAGCTGCGCACCGCCGGCCGCTGCCCCAGCTGCCCGAGCCCGCGCCCTCGTCCGCGCGACCCGGCGGGGGGCTCCAGGCCGGCAGCATGA
GCGGCGGCGGCGACGTGGTGTGCACCGGCTGGCTGAGGAAATCGCCTCCCGAGAAGAAGTTGAGGCGCTATCCATTCCACAGATTTTGAA
GTACACCGAAACTGGCTTGCTATCACTCACAGTTTGCCAATATCACAGTGGTATTATGAGGCAACTTCAGAGTGGACGTTGGATTACCCC
CCTTTCTTTGCATGGTTTGAGTATATCCTGTCACATGTTGCCAAATATTTTGATCAAGAAATGCTGAATGTCCATAATTTGAATTACTCC
AGCTCAAGGACCTTACTTTTCCAGAGATTTTCCGTCATCTTTATGGATGTACTCTTTGTGTATGCTGTCCGTGAGTGCTGTAAATGCATT
GATGGAAAAAAAGTGGGTAAAGAACTTACAGAAAAGCCAAAATTTATTCTGTCGGTATTACTTCTGTGGAACTTCGGGTTATTAATTGTG
GACCATATTCATTTTCAGTACAATGGCTTTTTATTTGGATTAATGCTACTCTCCATTGCACGATTATTTCAGAAAAGGCATATGGAAGGA
GCATTTCTCTTTGCTGTTCTCCTACATTTCAAGCATATCTACCTCTATGTAGCACCAGCTTATGGTGTATATCTGCTGCGATCCTACTGT
TTCACTGCAAATAAACCAGATGGGTCTATTCGATGGAAGAGTTTCAGCTTTGTTCGTGTTATTTCCCTGGGACTGGTTGTTTTCTTAGTT
TCTGCTCTTTCATTGGGTCCTTTCCTGGCCTTGAATCAGCTGCCTCAAGTCTTTTCCCGACTCTTTCCTTTCAAGAGGGGCCTCTGTCAT
GCATATTGGGCTCCAAACTTCTGGGCTTTGTACAATGCTTTGGACAAAGTGCTGTCTGTCATCGGTTTGAAATTGAAATTTCTTGATCCC
AACAATATTCCCAAGGCCTCAATGACAAGTGGTTTGGTTCAGCAGTTCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTC
ATCTGCACACTGATTGCCATATTGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTT
TGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGA
AAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCC
ATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGACGGAGTTTCACCCTTGTTGCCCAG
GCTGGAGTGCAATGGCACGATCTCAGCTAACTGAAACCTCCGCCTCCCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTAC
CTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTA
CTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTGGCAAGACA

>32025_32025_1_GAB2-ALG8_GAB2_chr11_78128691_ENST00000361507_ALG8_chr11_77838482_ENST00000376156_length(amino acids)=418AA_BP=
MPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTE
KPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIR
WKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSG
LVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLIL

--------------------------------------------------------------
>32025_32025_2_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77817992_ENST00000299626_length(transcript)=726nt_BP=161nt
GAGCTGCGCACCGCCGGCCGCTGCCCCAGCTGCCCGAGCCCGCGCCCTCGTCCGCGCGACCCGGCGGGGGGCTCCAGGCCGGCAGCATGA
GCGGCGGCGGCGACGTGGTGTGCACCGGCTGGCTGAGGAAATCGCCTCCCGAGAAGAAGTTGAGGCGCTATCCCTCTATTTTCTGTCTTT
GGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAA
AAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAG
GACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTT
CGTCACTGAAGACTTTATTCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCT
GCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCA
TCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTGGCAAGACAAAGAAACAATGAATAAAGGAACTGCTTA

>32025_32025_2_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77817992_ENST00000299626_length(amino acids)=227AA_BP=1
MPQLPEPAPSSARPGGGLQAGSMSGGGDVVCTGWLRKSPPEKKLRRYPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAI
LPMSLLSVGKAGDASIFLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFP

--------------------------------------------------------------
>32025_32025_3_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77817992_ENST00000376156_length(transcript)=796nt_BP=161nt
GAGCTGCGCACCGCCGGCCGCTGCCCCAGCTGCCCGAGCCCGCGCCCTCGTCCGCGCGACCCGGCGGGGGGCTCCAGGCCGGCAGCATGA
GCGGCGGCGGCGACGTGGTGTGCACCGGCTGGCTGAGGAAATCGCCTCCCGAGAAGAAGTTGAGGCGCTATCCCTCTATTTTCTGTCTTT
GGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTTGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAA
AAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAAAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAG
GACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTT
CGTCACTGAAGACTTTATTCAGACGGAGTTTCACCCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTCAGCTAACTGAAACCTCCGC
CTCCCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTAT
TCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGT

>32025_32025_3_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77817992_ENST00000376156_length(amino acids)=168AA_BP=1
MPQLPEPAPSSARPGGGLQAGSMSGGGDVVCTGWLRKSPPEKKLRRYPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAI

--------------------------------------------------------------
>32025_32025_4_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77825438_ENST00000299626_length(transcript)=1218nt_BP=161nt
GAGCTGCGCACCGCCGGCCGCTGCCCCAGCTGCCCGAGCCCGCGCCCTCGTCCGCGCGACCCGGCGGGGGGCTCCAGGCCGGCAGCATGA
GCGGCGGCGGCGACGTGGTGTGCACCGGCTGGCTGAGGAAATCGCCTCCCGAGAAGAAGTTGAGGCGCTATAAAAGGCATATGGAAGGAG
CATTTCTCTTTGCTGTTCTCCTACATTTCAAGCATATCTACCTCTATGTAGCACCAGCTTATGGTGTATATCTGCTGCGATCCTACTGTT
TCACTGCAAATAAACCAGATGGGTCTATTCGATGGAAGAGTTTCAGCTTTGTTCGTGTTATTTCCCTGGGACTGGTTGTTTTCTTAGTTT
CTGCTCTTTCATTGGGTCCTTTCCTGGCCTTGAATCAGCTGCCTCAAGTCTTTTCCCGACTCTTTCCTTTCAAGAGGGGCCTCTGTCATG
CATATTGGGCTCCAAACTTCTGGGCTTTGTACAATGCTTTGGACAAAGTGCTGTCTGTCATCGGTTTGAAATTGAAATTTCTTGATCCCA
ACAATATTCCCAAGGCCTCAATGACAAGTGGTTTGGTTCAGCAGTTCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTCA
TCTGCACACTGATTGCCATATTGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTT
GTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAA
AAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCA
TTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGAAAAGAAAAACCTCTTTTTAATTGGA
TGGAAACTTTCTACCTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCT
TCATCCCTTTGTTACTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTG

>32025_32025_4_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77825438_ENST00000299626_length(amino acids)=391AA_BP=1
MPQLPEPAPSSARPGGGLQAGSMSGGGDVVCTGWLRKSPPEKKLRRYKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPD
GSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKAS
MTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASI
FLILTTTGHYSLFPLLFTAPELPIKILLMLLFTIYSISSLKTLFRKEKPLFNWMETFYLLGLGPLEVCCEFVFPFTSWKVKYPFIPLLLT

--------------------------------------------------------------
>32025_32025_5_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77825438_ENST00000376156_length(transcript)=1288nt_BP=161nt
GAGCTGCGCACCGCCGGCCGCTGCCCCAGCTGCCCGAGCCCGCGCCCTCGTCCGCGCGACCCGGCGGGGGGCTCCAGGCCGGCAGCATGA
GCGGCGGCGGCGACGTGGTGTGCACCGGCTGGCTGAGGAAATCGCCTCCCGAGAAGAAGTTGAGGCGCTATAAAAGGCATATGGAAGGAG
CATTTCTCTTTGCTGTTCTCCTACATTTCAAGCATATCTACCTCTATGTAGCACCAGCTTATGGTGTATATCTGCTGCGATCCTACTGTT
TCACTGCAAATAAACCAGATGGGTCTATTCGATGGAAGAGTTTCAGCTTTGTTCGTGTTATTTCCCTGGGACTGGTTGTTTTCTTAGTTT
CTGCTCTTTCATTGGGTCCTTTCCTGGCCTTGAATCAGCTGCCTCAAGTCTTTTCCCGACTCTTTCCTTTCAAGAGGGGCCTCTGTCATG
CATATTGGGCTCCAAACTTCTGGGCTTTGTACAATGCTTTGGACAAAGTGCTGTCTGTCATCGGTTTGAAATTGAAATTTCTTGATCCCA
ACAATATTCCCAAGGCCTCAATGACAAGTGGTTTGGTTCAGCAGTTCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTCA
TCTGCACACTGATTGCCATATTGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTTT
GTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGAA
AAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCCA
TTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGACGGAGTTTCACCCTTGTTGCCCAGG
CTGGAGTGCAATGGCACGATCTCAGCTAACTGAAACCTCCGCCTCCCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTACC
TGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTAC
TAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTGGCAAGACAA

>32025_32025_5_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77825438_ENST00000376156_length(amino acids)=332AA_BP=1
MPQLPEPAPSSARPGGGLQAGSMSGGGDVVCTGWLRKSPPEKKLRRYKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPD
GSIRWKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKAS
MTSGLVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASI

--------------------------------------------------------------
>32025_32025_6_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77838482_ENST00000376156_length(transcript)=1739nt_BP=161nt
GAGCTGCGCACCGCCGGCCGCTGCCCCAGCTGCCCGAGCCCGCGCCCTCGTCCGCGCGACCCGGCGGGGGGCTCCAGGCCGGCAGCATGA
GCGGCGGCGGCGACGTGGTGTGCACCGGCTGGCTGAGGAAATCGCCTCCCGAGAAGAAGTTGAGGCGCTATCCATTCCACAGATTTTGAA
GTACACCGAAACTGGCTTGCTATCACTCACAGTTTGCCAATATCACAGTGGTATTATGAGGCAACTTCAGAGTGGACGTTGGATTACCCC
CCTTTCTTTGCATGGTTTGAGTATATCCTGTCACATGTTGCCAAATATTTTGATCAAGAAATGCTGAATGTCCATAATTTGAATTACTCC
AGCTCAAGGACCTTACTTTTCCAGAGATTTTCCGTCATCTTTATGGATGTACTCTTTGTGTATGCTGTCCGTGAGTGCTGTAAATGCATT
GATGGAAAAAAAGTGGGTAAAGAACTTACAGAAAAGCCAAAATTTATTCTGTCGGTATTACTTCTGTGGAACTTCGGGTTATTAATTGTG
GACCATATTCATTTTCAGTACAATGGCTTTTTATTTGGATTAATGCTACTCTCCATTGCACGATTATTTCAGAAAAGGCATATGGAAGGA
GCATTTCTCTTTGCTGTTCTCCTACATTTCAAGCATATCTACCTCTATGTAGCACCAGCTTATGGTGTATATCTGCTGCGATCCTACTGT
TTCACTGCAAATAAACCAGATGGGTCTATTCGATGGAAGAGTTTCAGCTTTGTTCGTGTTATTTCCCTGGGACTGGTTGTTTTCTTAGTT
TCTGCTCTTTCATTGGGTCCTTTCCTGGCCTTGAATCAGCTGCCTCAAGTCTTTTCCCGACTCTTTCCTTTCAAGAGGGGCCTCTGTCAT
GCATATTGGGCTCCAAACTTCTGGGCTTTGTACAATGCTTTGGACAAAGTGCTGTCTGTCATCGGTTTGAAATTGAAATTTCTTGATCCC
AACAATATTCCCAAGGCCTCAATGACAAGTGGTTTGGTTCAGCAGTTCCAACACACAGTCCTTCCCTCAGTGACTCCCTTGGCAACCCTC
ATCTGCACACTGATTGCCATATTGCCCTCTATTTTCTGTCTTTGGTTTAAACCCCAAGGGCCCAGAGGCTTTCTCCGATGTCTAACTCTT
TGTGCCTTGAGCTCCTTTATGTTTGGGTGGCATGTTCATGAAAAAGCCATACTTCTAGCAATTCTCCCAATGAGCCTTTTGTCTGTGGGA
AAAGCAGGAGACGCTTCGATTTTTCTGATTCTGACCACAACAGGACATTATTCCCTCTTTCCTCTGCTCTTCACTGCACCAGAACTTCCC
ATTAAAATCTTACTCATGTTACTATTCACCATATATAGTATTTCGTCACTGAAGACTTTATTCAGACGGAGTTTCACCCTTGTTGCCCAG
GCTGGAGTGCAATGGCACGATCTCAGCTAACTGAAACCTCCGCCTCCCAGAAAAGAAAAACCTCTTTTTAATTGGATGGAAACTTTCTAC
CTGCTTGGCCTGGGGCCTCTGGAAGTCTGCTGTGAATTTGTATTCCCTTTCACCTCCTGGAAGGTGAAGTACCCCTTCATCCCTTTGTTA
CTAACCTCAGTGTATTGTGCAGTAGGCATCACATATGCTTGGTTCAAACTGTATGTTTCAGTATTGATTGACTCTGCTATTGGCAAGACA

>32025_32025_6_GAB2-ALG8_GAB2_chr11_78128692_ENST00000361507_ALG8_chr11_77838482_ENST00000376156_length(amino acids)=418AA_BP=
MPISQWYYEATSEWTLDYPPFFAWFEYILSHVAKYFDQEMLNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELTE
KPKFILSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRSYCFTANKPDGSIR
WKSFSFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHAYWAPNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSG
LVQQFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGWHVHEKAILLAILPMSLLSVGKAGDASIFLIL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GAB2-ALG8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GAB2-ALG8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GAB2-ALG8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource