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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:GABRP-RANBP17 (FusionGDB2 ID:32146) |
Fusion Gene Summary for GABRP-RANBP17 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GABRP-RANBP17 | Fusion gene ID: 32146 | Hgene | Tgene | Gene symbol | GABRP | RANBP17 | Gene ID | 2568 | 64901 |
| Gene name | gamma-aminobutyric acid type A receptor subunit pi | RAN binding protein 17 | |
| Synonyms | - | - | |
| Cytomap | 5q35.1 | 5q35.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | gamma-aminobutyric acid receptor subunit piGABA(A) receptor subunit piGABA(A) receptor, pigamma-aminobutyric acid (GABA) A receptor, pigamma-aminobutyric acid type A receptor pi subunit | ran-binding protein 17 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000265294, ENST00000518525, ENST00000519385, ENST00000519598, | ENST00000521759, ENST00000523189, | |
| Fusion gene scores | * DoF score | 2 X 3 X 3=18 | 6 X 9 X 4=216 |
| # samples | 4 | 8 | |
| ** MAII score | log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(8/216*10)=-1.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GABRP [Title/Abstract] AND RANBP17 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | GABRP(170216251)-RANBP17(170380601), # samples:2 RANBP17(170308900)-GABRP(170238960), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | RANBP17-GABRP seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. RANBP17-GABRP seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across GABRP (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across RANBP17 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STAD | TCGA-D7-A4YY-01A | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
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Fusion Gene ORF analysis for GABRP-RANBP17 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000265294 | ENST00000521759 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| 5CDS-intron | ENST00000518525 | ENST00000521759 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| 5CDS-intron | ENST00000519385 | ENST00000521759 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| 5CDS-intron | ENST00000519598 | ENST00000521759 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| In-frame | ENST00000265294 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| In-frame | ENST00000518525 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| In-frame | ENST00000519385 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| In-frame | ENST00000519598 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000518525 | GABRP | chr5 | 170216251 | + | ENST00000523189 | RANBP17 | chr5 | 170380601 | + | 3592 | 636 | 419 | 2434 | 671 |
| ENST00000265294 | GABRP | chr5 | 170216251 | + | ENST00000523189 | RANBP17 | chr5 | 170380601 | + | 3326 | 370 | 153 | 2168 | 671 |
| ENST00000519385 | GABRP | chr5 | 170216251 | + | ENST00000523189 | RANBP17 | chr5 | 170380601 | + | 3320 | 364 | 147 | 2162 | 671 |
| ENST00000519598 | GABRP | chr5 | 170216251 | + | ENST00000523189 | RANBP17 | chr5 | 170380601 | + | 3298 | 342 | 125 | 2140 | 671 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000518525 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + | 0.001032336 | 0.99896765 |
| ENST00000265294 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + | 0.000790913 | 0.9992091 |
| ENST00000519385 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + | 0.000778888 | 0.9992211 |
| ENST00000519598 | ENST00000523189 | GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380601 | + | 0.000778586 | 0.99922144 |
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Fusion Genomic Features for GABRP-RANBP17 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380600 | + | 0.1405419 | 0.85945815 |
| GABRP | chr5 | 170216251 | + | RANBP17 | chr5 | 170380600 | + | 0.1405419 | 0.85945815 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for GABRP-RANBP17 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:170216251/chr5:170380601) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000265294 | + | 3 | 10 | 17_242 | 57 | 441.0 | Topological domain | Extracellular |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000265294 | + | 3 | 10 | 328_416 | 57 | 441.0 | Topological domain | Cytoplasmic |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000518525 | + | 4 | 11 | 17_242 | 57 | 441.0 | Topological domain | Extracellular |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000518525 | + | 4 | 11 | 328_416 | 57 | 441.0 | Topological domain | Cytoplasmic |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000265294 | + | 3 | 10 | 243_266 | 57 | 441.0 | Transmembrane | Helical |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000265294 | + | 3 | 10 | 270_292 | 57 | 441.0 | Transmembrane | Helical |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000265294 | + | 3 | 10 | 305_327 | 57 | 441.0 | Transmembrane | Helical |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000265294 | + | 3 | 10 | 417_438 | 57 | 441.0 | Transmembrane | Helical |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000518525 | + | 4 | 11 | 243_266 | 57 | 441.0 | Transmembrane | Helical |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000518525 | + | 4 | 11 | 270_292 | 57 | 441.0 | Transmembrane | Helical |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000518525 | + | 4 | 11 | 305_327 | 57 | 441.0 | Transmembrane | Helical |
| Hgene | GABRP | chr5:170216251 | chr5:170380601 | ENST00000518525 | + | 4 | 11 | 417_438 | 57 | 441.0 | Transmembrane | Helical |
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Fusion Gene Sequence for GABRP-RANBP17 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >32146_32146_1_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000265294_RANBP17_chr5_170380601_ENST00000523189_length(transcript)=3326nt_BP=370nt AGAGCCACTCCATCTGAGGGTGGCTGCGTGTCCACATACGAGGGGACAGGGCTGAGGATGAGGAGAACCCTGGGGACCCAGAAGACCGTG CCTTGCCTGGAAGTCCTGCCTGTAGGCCTGAAGGACTTGCCCTAACAGAGCCTCAACAACTACCTGGTGATTCCTACTTCAGCCCCTTGG TGTGAGCAGCTTCTCAACATGAACTACAGCCTCCACTTGGCCTTCGTGTGTCTGAGTCTCTTCACTGAGAGGATGTGCATCCAGGGGAGT CAGTTCAACGTCGAGGTCGGCAGAAGTGACAAGCTTTCCCTGCCTGGCTTTGAGAACCTCACAGCAGGATATAACAAATTTCTCAGGCCC AATTTTGGTGGACGTCTTGCATGGCTGGTATACTTAGTTGGGACAGTTGTAGGAGGAAGATTAACATATACCAGTACAGATGAGCATGAT GCTATGGATGGAGAATTATCCTGTCGAGTTTTTCAGCTTATATCTTTAATGGATACCGGATTGCCTCGATGTTGTAATGAGAAAATAGAG CTTGCAATTCTGTGGTTCTTGGATCAGTTTCGTAAAACATATGTTGGTGATCAACTTCAAAGAACCTCAAAGGTATATGCTCGTATGTCA GAAGTCTTAGGAATAACAGATGACAACCACGTTCTAGAGACGTTCATGACAAAAATTGTTACAAACCTTAAATACTGGGGAAGATATGAG CCTGTAATTTCAAGGACTCTTCAGTTCCTAAATGACCTTTCTGTTGGTTATATCCTTTTAAAAAAACTTGTGAAGATAGATGCTGTGAAA TTCATGCTAAAAAACCACACGAGTGAACACTTCCCTTTTCTTGGCATCAGTGACAATCATAGTCTCAGCGACTTCAGGTGTCGAACAACC TTCTACACAGCGCTCACTCGCCTTCTGATGGTAGATCTGGGTGAAGATGAGGATGAATTTGAGAATTTCATGCTGCCTCTTACAGTTGCT TTTGAAACAGTATTACAAATATTCAACAACAACTTTAAACAAGAAGATGTAAAGCGTATGTTGATCGGGCTGGCAAGAGATCTTCGAGGG ATTGCCTTTGCACTGAACACAAAGACCAGCTACACCATGCTGTTTGACTGGATGTACCCAACGTACCTTCCCCTTCTTCAGAATGCTGTT GAACGGTGGTATGGAGAGCCAACATGTACAACTCCCATCTTGAAACTTATGGCAGAACTTATGCAAAACAGATCCCAGCGTTTGAATTTT GATGTATCATCTCCTAATGGAATTCTTCTCTTCAGAGAAGCTAGTAAAATGGTTTGCACTTATGGTAATCAGATCCTGTCCCTTGGGAGC CTCTCAAAAGATCAGATTTATCCAATGAAACTCAAGGGCATCTCCATCTGCTATTCAGCTCTCAAGTCTGCCTTGTGTGGAAATTATGTC AGCTTTGGCGTCTTCAAGTTGTATGGGGACAACCATTTTGACAATGTACTCCAGGCTTTTGTCAAAATGCTGCTGTCAGTGTCCCACAGT GACTTGCTACAATACCGGAAACTGAGCCAGTCTTATTATCCACTCCTGGAATGTCTCACTCAGGACCATATGAGCTTCATCATCAACTTA GAGCCTCCTGTACTCATGTATGTTCTCACATCTATCTCAGAGGGACTCACTACTCTTGATACAGTTGTCTCCTCCAGCTGCTGTACCAGT TTAGACTACATCGTCACCTACCTCTTCAAGCACATAGCAAAAGAGGGCAAGAAGCCACTTCGATGCAGAGAGGCTACCCAGGCTGGTCAG AGACTATTACATTTTATGCAGCAAAACCCAGATGTCCTGCAGCAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGACTGTCGG AACCAGTGGTCAGTATCCAGGCCTCTCCTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGATAAACAGC CAGCCCCTCCCCAAGCAGGAGGTCCTTGCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAACAGAGAC AGGTTCACCCAAAATCTGTCTGTATTCAGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCTCGACATG ATGAGCTGACCCGACTTTTCTGACCATGTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGATGTTGGCT AGCCCAGGGGAATGTATTTTTCAAAACATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAATTTCTAAC AGTACCAGTGTAAATTCAGTCTTTTCTCTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCCTAATGCT CTGAAAGGATGTAGAAACAATATTTAACCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTGCAGTCAA GGTTGTCAATTTGTTGGAGATGCAGCCTTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGTTTGTTAT GTGTCTGGAAGAAGCAGCGTTAGGGACTTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGACCACACG CAGGCCTCCCTGCCTCAGCTGCATCTGATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTCACTGGCA TAAATCTGAAGTGGTTCAGTCTAGAAGAATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAGCCCCAGT CAGAAGTTCTGGGTGGTGCCAGCACCCAGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATAATATTTG AAGCAGCTCTGCCTTCTTAGGGCTACCCAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTTTCCAACT CTCCACAAAAACTCTTATTACTGTTGGGACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTTGTGCTCT ACTGTTACTAGGCTATTAATTTGAGATCGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATAACAAATA >32146_32146_1_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000265294_RANBP17_chr5_170380601_ENST00000523189_length(amino acids)=671AA_BP=1 MVIPTSAPWCEQLLNMNYSLHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGRLAWLVYLVGTVVGGRL TYTSTDEHDAMDGELSCRVFQLISLMDTGLPRCCNEKIELAILWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMTKIVT NLKYWGRYEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDNHSLSDFRCRTTFYTALTRLLMVDLGEDEDEFE NFMLPLTVAFETVLQIFNNNFKQEDVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMYPTYLPLLQNAVERWYGEPTCTTPILKLMAELM QNRSQRLNFDVSSPNGILLFREASKMVCTYGNQILSLGSLSKDQIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFV KMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTLDTVVSSSCCTSLDYIVTYLFKHIAKEGKKPLR CREATQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLAQCFRNLMEGVE -------------------------------------------------------------- >32146_32146_2_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000518525_RANBP17_chr5_170380601_ENST00000523189_length(transcript)=3592nt_BP=636nt CTGCCCCTCCATTTGCTCCCCTTCCTTTCTCTCTCTCCCTTCCCGGCTCCTAGACTGGGTCTAGGCAGGAGCTTCGCCATGATGTCAGGA GGGAAGGAGATGCCTCTGGGCCTCGTACCACAGCCTCAGCTCTCTCTCTGCCCCTCCATCTGAGTCCCTCCTGGCTCCCAGCTCCCTCAG GGTGCAAGGCCAAGCCTCCAAGGAATCCCTCCCCTTACCTGCATGGCTGGAGCCAAGACAGGTTTAGCAGCTCCATTCTTCCCCAGAGAG CCACTCCATCTGAGGGTGGCTGCGTGTCCACATACGAGGGGACAGGGCTGAGGATGAGGAGAACCCTGGGGACCCAGAAGACCGTGCCTT GCCTGGAAGTCCTGCCTGTAGGCCTGAAGGACTTGCCCTAACAGAGCCTCAACAACTACCTGGTGATTCCTACTTCAGCCCCTTGGTGTG AGCAGCTTCTCAACATGAACTACAGCCTCCACTTGGCCTTCGTGTGTCTGAGTCTCTTCACTGAGAGGATGTGCATCCAGGGGAGTCAGT TCAACGTCGAGGTCGGCAGAAGTGACAAGCTTTCCCTGCCTGGCTTTGAGAACCTCACAGCAGGATATAACAAATTTCTCAGGCCCAATT TTGGTGGACGTCTTGCATGGCTGGTATACTTAGTTGGGACAGTTGTAGGAGGAAGATTAACATATACCAGTACAGATGAGCATGATGCTA TGGATGGAGAATTATCCTGTCGAGTTTTTCAGCTTATATCTTTAATGGATACCGGATTGCCTCGATGTTGTAATGAGAAAATAGAGCTTG CAATTCTGTGGTTCTTGGATCAGTTTCGTAAAACATATGTTGGTGATCAACTTCAAAGAACCTCAAAGGTATATGCTCGTATGTCAGAAG TCTTAGGAATAACAGATGACAACCACGTTCTAGAGACGTTCATGACAAAAATTGTTACAAACCTTAAATACTGGGGAAGATATGAGCCTG TAATTTCAAGGACTCTTCAGTTCCTAAATGACCTTTCTGTTGGTTATATCCTTTTAAAAAAACTTGTGAAGATAGATGCTGTGAAATTCA TGCTAAAAAACCACACGAGTGAACACTTCCCTTTTCTTGGCATCAGTGACAATCATAGTCTCAGCGACTTCAGGTGTCGAACAACCTTCT ACACAGCGCTCACTCGCCTTCTGATGGTAGATCTGGGTGAAGATGAGGATGAATTTGAGAATTTCATGCTGCCTCTTACAGTTGCTTTTG AAACAGTATTACAAATATTCAACAACAACTTTAAACAAGAAGATGTAAAGCGTATGTTGATCGGGCTGGCAAGAGATCTTCGAGGGATTG CCTTTGCACTGAACACAAAGACCAGCTACACCATGCTGTTTGACTGGATGTACCCAACGTACCTTCCCCTTCTTCAGAATGCTGTTGAAC GGTGGTATGGAGAGCCAACATGTACAACTCCCATCTTGAAACTTATGGCAGAACTTATGCAAAACAGATCCCAGCGTTTGAATTTTGATG TATCATCTCCTAATGGAATTCTTCTCTTCAGAGAAGCTAGTAAAATGGTTTGCACTTATGGTAATCAGATCCTGTCCCTTGGGAGCCTCT CAAAAGATCAGATTTATCCAATGAAACTCAAGGGCATCTCCATCTGCTATTCAGCTCTCAAGTCTGCCTTGTGTGGAAATTATGTCAGCT TTGGCGTCTTCAAGTTGTATGGGGACAACCATTTTGACAATGTACTCCAGGCTTTTGTCAAAATGCTGCTGTCAGTGTCCCACAGTGACT TGCTACAATACCGGAAACTGAGCCAGTCTTATTATCCACTCCTGGAATGTCTCACTCAGGACCATATGAGCTTCATCATCAACTTAGAGC CTCCTGTACTCATGTATGTTCTCACATCTATCTCAGAGGGACTCACTACTCTTGATACAGTTGTCTCCTCCAGCTGCTGTACCAGTTTAG ACTACATCGTCACCTACCTCTTCAAGCACATAGCAAAAGAGGGCAAGAAGCCACTTCGATGCAGAGAGGCTACCCAGGCTGGTCAGAGAC TATTACATTTTATGCAGCAAAACCCAGATGTCCTGCAGCAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGACTGTCGGAACC AGTGGTCAGTATCCAGGCCTCTCCTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGATAAACAGCCAGC CCCTCCCCAAGCAGGAGGTCCTTGCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAACAGAGACAGGT TCACCCAAAATCTGTCTGTATTCAGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCTCGACATGATGA GCTGACCCGACTTTTCTGACCATGTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGATGTTGGCTAGCC CAGGGGAATGTATTTTTCAAAACATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAATTTCTAACAGTA CCAGTGTAAATTCAGTCTTTTCTCTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCCTAATGCTCTGA AAGGATGTAGAAACAATATTTAACCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTGCAGTCAAGGTT GTCAATTTGTTGGAGATGCAGCCTTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGTTTGTTATGTGT CTGGAAGAAGCAGCGTTAGGGACTTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGACCACACGCAGG CCTCCCTGCCTCAGCTGCATCTGATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTCACTGGCATAAA TCTGAAGTGGTTCAGTCTAGAAGAATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAGCCCCAGTCAGA AGTTCTGGGTGGTGCCAGCACCCAGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATAATATTTGAAGC AGCTCTGCCTTCTTAGGGCTACCCAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTTTCCAACTCTCC ACAAAAACTCTTATTACTGTTGGGACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTTGTGCTCTACTG TTACTAGGCTATTAATTTGAGATCGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATAACAAATATTGT >32146_32146_2_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000518525_RANBP17_chr5_170380601_ENST00000523189_length(amino acids)=671AA_BP=1 MVIPTSAPWCEQLLNMNYSLHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGRLAWLVYLVGTVVGGRL TYTSTDEHDAMDGELSCRVFQLISLMDTGLPRCCNEKIELAILWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMTKIVT NLKYWGRYEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDNHSLSDFRCRTTFYTALTRLLMVDLGEDEDEFE NFMLPLTVAFETVLQIFNNNFKQEDVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMYPTYLPLLQNAVERWYGEPTCTTPILKLMAELM QNRSQRLNFDVSSPNGILLFREASKMVCTYGNQILSLGSLSKDQIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFV KMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTLDTVVSSSCCTSLDYIVTYLFKHIAKEGKKPLR CREATQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLAQCFRNLMEGVE -------------------------------------------------------------- >32146_32146_3_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000519385_RANBP17_chr5_170380601_ENST00000523189_length(transcript)=3320nt_BP=364nt ACTCCATCTGAGGGTGGCTGCGTGTCCACATACGAGGGGACAGGGCTGAGGATGAGGAGAACCCTGGGGACCCAGAAGACCGTGCCTTGC CTGGAAGTCCTGCCTGTAGGCCTGAAGGACTTGCCCTAACAGAGCCTCAACAACTACCTGGTGATTCCTACTTCAGCCCCTTGGTGTGAG CAGCTTCTCAACATGAACTACAGCCTCCACTTGGCCTTCGTGTGTCTGAGTCTCTTCACTGAGAGGATGTGCATCCAGGGGAGTCAGTTC AACGTCGAGGTCGGCAGAAGTGACAAGCTTTCCCTGCCTGGCTTTGAGAACCTCACAGCAGGATATAACAAATTTCTCAGGCCCAATTTT GGTGGACGTCTTGCATGGCTGGTATACTTAGTTGGGACAGTTGTAGGAGGAAGATTAACATATACCAGTACAGATGAGCATGATGCTATG GATGGAGAATTATCCTGTCGAGTTTTTCAGCTTATATCTTTAATGGATACCGGATTGCCTCGATGTTGTAATGAGAAAATAGAGCTTGCA ATTCTGTGGTTCTTGGATCAGTTTCGTAAAACATATGTTGGTGATCAACTTCAAAGAACCTCAAAGGTATATGCTCGTATGTCAGAAGTC TTAGGAATAACAGATGACAACCACGTTCTAGAGACGTTCATGACAAAAATTGTTACAAACCTTAAATACTGGGGAAGATATGAGCCTGTA ATTTCAAGGACTCTTCAGTTCCTAAATGACCTTTCTGTTGGTTATATCCTTTTAAAAAAACTTGTGAAGATAGATGCTGTGAAATTCATG CTAAAAAACCACACGAGTGAACACTTCCCTTTTCTTGGCATCAGTGACAATCATAGTCTCAGCGACTTCAGGTGTCGAACAACCTTCTAC ACAGCGCTCACTCGCCTTCTGATGGTAGATCTGGGTGAAGATGAGGATGAATTTGAGAATTTCATGCTGCCTCTTACAGTTGCTTTTGAA ACAGTATTACAAATATTCAACAACAACTTTAAACAAGAAGATGTAAAGCGTATGTTGATCGGGCTGGCAAGAGATCTTCGAGGGATTGCC TTTGCACTGAACACAAAGACCAGCTACACCATGCTGTTTGACTGGATGTACCCAACGTACCTTCCCCTTCTTCAGAATGCTGTTGAACGG TGGTATGGAGAGCCAACATGTACAACTCCCATCTTGAAACTTATGGCAGAACTTATGCAAAACAGATCCCAGCGTTTGAATTTTGATGTA TCATCTCCTAATGGAATTCTTCTCTTCAGAGAAGCTAGTAAAATGGTTTGCACTTATGGTAATCAGATCCTGTCCCTTGGGAGCCTCTCA AAAGATCAGATTTATCCAATGAAACTCAAGGGCATCTCCATCTGCTATTCAGCTCTCAAGTCTGCCTTGTGTGGAAATTATGTCAGCTTT GGCGTCTTCAAGTTGTATGGGGACAACCATTTTGACAATGTACTCCAGGCTTTTGTCAAAATGCTGCTGTCAGTGTCCCACAGTGACTTG CTACAATACCGGAAACTGAGCCAGTCTTATTATCCACTCCTGGAATGTCTCACTCAGGACCATATGAGCTTCATCATCAACTTAGAGCCT CCTGTACTCATGTATGTTCTCACATCTATCTCAGAGGGACTCACTACTCTTGATACAGTTGTCTCCTCCAGCTGCTGTACCAGTTTAGAC TACATCGTCACCTACCTCTTCAAGCACATAGCAAAAGAGGGCAAGAAGCCACTTCGATGCAGAGAGGCTACCCAGGCTGGTCAGAGACTA TTACATTTTATGCAGCAAAACCCAGATGTCCTGCAGCAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGACTGTCGGAACCAG TGGTCAGTATCCAGGCCTCTCCTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGATAAACAGCCAGCCC CTCCCCAAGCAGGAGGTCCTTGCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAACAGAGACAGGTTC ACCCAAAATCTGTCTGTATTCAGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCTCGACATGATGAGC TGACCCGACTTTTCTGACCATGTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGATGTTGGCTAGCCCA GGGGAATGTATTTTTCAAAACATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAATTTCTAACAGTACC AGTGTAAATTCAGTCTTTTCTCTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCCTAATGCTCTGAAA GGATGTAGAAACAATATTTAACCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTGCAGTCAAGGTTGT CAATTTGTTGGAGATGCAGCCTTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGTTTGTTATGTGTCT GGAAGAAGCAGCGTTAGGGACTTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGACCACACGCAGGCC TCCCTGCCTCAGCTGCATCTGATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTCACTGGCATAAATC TGAAGTGGTTCAGTCTAGAAGAATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAGCCCCAGTCAGAAG TTCTGGGTGGTGCCAGCACCCAGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATAATATTTGAAGCAG CTCTGCCTTCTTAGGGCTACCCAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTTTCCAACTCTCCAC AAAAACTCTTATTACTGTTGGGACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTTGTGCTCTACTGTT ACTAGGCTATTAATTTGAGATCGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATAACAAATATTGTAT >32146_32146_3_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000519385_RANBP17_chr5_170380601_ENST00000523189_length(amino acids)=671AA_BP=1 MVIPTSAPWCEQLLNMNYSLHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGRLAWLVYLVGTVVGGRL TYTSTDEHDAMDGELSCRVFQLISLMDTGLPRCCNEKIELAILWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMTKIVT NLKYWGRYEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDNHSLSDFRCRTTFYTALTRLLMVDLGEDEDEFE NFMLPLTVAFETVLQIFNNNFKQEDVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMYPTYLPLLQNAVERWYGEPTCTTPILKLMAELM QNRSQRLNFDVSSPNGILLFREASKMVCTYGNQILSLGSLSKDQIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFV KMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTLDTVVSSSCCTSLDYIVTYLFKHIAKEGKKPLR CREATQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLAQCFRNLMEGVE -------------------------------------------------------------- >32146_32146_4_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000519598_RANBP17_chr5_170380601_ENST00000523189_length(transcript)=3298nt_BP=342nt TGTCCACATACGAGGGGACAGGGCTGAGGATGAGGAGAACCCTGGGGACCCAGAAGACCGTGCCTTGCCTGGAAGTCCTGCCTGTAGGCC TGAAGGACTTGCCCTAACAGAGCCTCAACAACTACCTGGTGATTCCTACTTCAGCCCCTTGGTGTGAGCAGCTTCTCAACATGAACTACA GCCTCCACTTGGCCTTCGTGTGTCTGAGTCTCTTCACTGAGAGGATGTGCATCCAGGGGAGTCAGTTCAACGTCGAGGTCGGCAGAAGTG ACAAGCTTTCCCTGCCTGGCTTTGAGAACCTCACAGCAGGATATAACAAATTTCTCAGGCCCAATTTTGGTGGACGTCTTGCATGGCTGG TATACTTAGTTGGGACAGTTGTAGGAGGAAGATTAACATATACCAGTACAGATGAGCATGATGCTATGGATGGAGAATTATCCTGTCGAG TTTTTCAGCTTATATCTTTAATGGATACCGGATTGCCTCGATGTTGTAATGAGAAAATAGAGCTTGCAATTCTGTGGTTCTTGGATCAGT TTCGTAAAACATATGTTGGTGATCAACTTCAAAGAACCTCAAAGGTATATGCTCGTATGTCAGAAGTCTTAGGAATAACAGATGACAACC ACGTTCTAGAGACGTTCATGACAAAAATTGTTACAAACCTTAAATACTGGGGAAGATATGAGCCTGTAATTTCAAGGACTCTTCAGTTCC TAAATGACCTTTCTGTTGGTTATATCCTTTTAAAAAAACTTGTGAAGATAGATGCTGTGAAATTCATGCTAAAAAACCACACGAGTGAAC ACTTCCCTTTTCTTGGCATCAGTGACAATCATAGTCTCAGCGACTTCAGGTGTCGAACAACCTTCTACACAGCGCTCACTCGCCTTCTGA TGGTAGATCTGGGTGAAGATGAGGATGAATTTGAGAATTTCATGCTGCCTCTTACAGTTGCTTTTGAAACAGTATTACAAATATTCAACA ACAACTTTAAACAAGAAGATGTAAAGCGTATGTTGATCGGGCTGGCAAGAGATCTTCGAGGGATTGCCTTTGCACTGAACACAAAGACCA GCTACACCATGCTGTTTGACTGGATGTACCCAACGTACCTTCCCCTTCTTCAGAATGCTGTTGAACGGTGGTATGGAGAGCCAACATGTA CAACTCCCATCTTGAAACTTATGGCAGAACTTATGCAAAACAGATCCCAGCGTTTGAATTTTGATGTATCATCTCCTAATGGAATTCTTC TCTTCAGAGAAGCTAGTAAAATGGTTTGCACTTATGGTAATCAGATCCTGTCCCTTGGGAGCCTCTCAAAAGATCAGATTTATCCAATGA AACTCAAGGGCATCTCCATCTGCTATTCAGCTCTCAAGTCTGCCTTGTGTGGAAATTATGTCAGCTTTGGCGTCTTCAAGTTGTATGGGG ACAACCATTTTGACAATGTACTCCAGGCTTTTGTCAAAATGCTGCTGTCAGTGTCCCACAGTGACTTGCTACAATACCGGAAACTGAGCC AGTCTTATTATCCACTCCTGGAATGTCTCACTCAGGACCATATGAGCTTCATCATCAACTTAGAGCCTCCTGTACTCATGTATGTTCTCA CATCTATCTCAGAGGGACTCACTACTCTTGATACAGTTGTCTCCTCCAGCTGCTGTACCAGTTTAGACTACATCGTCACCTACCTCTTCA AGCACATAGCAAAAGAGGGCAAGAAGCCACTTCGATGCAGAGAGGCTACCCAGGCTGGTCAGAGACTATTACATTTTATGCAGCAAAACC CAGATGTCCTGCAGCAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGACTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTCC TGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGATAAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTTG CCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAACAGAGACAGGTTCACCCAAAATCTGTCTGTATTCA GAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCTCGACATGATGAGCTGACCCGACTTTTCTGACCATG TGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGATGTTGGCTAGCCCAGGGGAATGTATTTTTCAAAACA TACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAATTTCTAACAGTACCAGTGTAAATTCAGTCTTTTCTC TGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCCTAATGCTCTGAAAGGATGTAGAAACAATATTTAAC CAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTGCAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCCT TCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGTTTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGACT TTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGACCACACGCAGGCCTCCCTGCCTCAGCTGCATCTGA TAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTCACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAGA ATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAGCCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCCA GTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATAATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACCC AAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTTTCCAACTCTCCACAAAAACTCTTATTACTGTTGGG ACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTTGTGCTCTACTGTTACTAGGCTATTAATTTGAGATC GTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATAACAAATATTGTATCCTTTATTTCTGATAAGACATG >32146_32146_4_GABRP-RANBP17_GABRP_chr5_170216251_ENST00000519598_RANBP17_chr5_170380601_ENST00000523189_length(amino acids)=671AA_BP=1 MVIPTSAPWCEQLLNMNYSLHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGRLAWLVYLVGTVVGGRL TYTSTDEHDAMDGELSCRVFQLISLMDTGLPRCCNEKIELAILWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMTKIVT NLKYWGRYEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDNHSLSDFRCRTTFYTALTRLLMVDLGEDEDEFE NFMLPLTVAFETVLQIFNNNFKQEDVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMYPTYLPLLQNAVERWYGEPTCTTPILKLMAELM QNRSQRLNFDVSSPNGILLFREASKMVCTYGNQILSLGSLSKDQIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFV KMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTLDTVVSSSCCTSLDYIVTYLFKHIAKEGKKPLR CREATQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLAQCFRNLMEGVE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for GABRP-RANBP17 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for GABRP-RANBP17 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for GABRP-RANBP17 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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