FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:GALNT11-CNTNAP2 (FusionGDB2 ID:32220)

Fusion Gene Summary for GALNT11-CNTNAP2

check button Fusion gene summary
Fusion gene informationFusion gene name: GALNT11-CNTNAP2
Fusion gene ID: 32220
HgeneTgene
Gene symbol

GALNT11

CNTNAP2

Gene ID

63917

26047

Gene namepolypeptide N-acetylgalactosaminyltransferase 11contactin associated protein 2
SynonymsGALNAC-T11|GALNACT11AUTS15|CASPR2|CDFE|NRXN4|PTHSL1
Cytomap

7q36.1|7q36.1

7q35-q36.1

Type of geneprotein-codingprotein-coding
Descriptionpolypeptide N-acetylgalactosaminyltransferase 11UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)polypeptide GalNAc transferase 11pp-GaNTase 11pcontactin-associated protein-like 2cell recognition molecule Caspr2contactin associated protein like 2homolog of Drosophila neurexin IV
Modification date2020031320200313
UniProtAcc.

Q9UHC6

Ensembl transtripts involved in fusion geneENST00000482812, ENST00000452146, 
ENST00000430044, ENST00000320311, 
ENST00000415421, ENST00000422997, 
ENST00000434507, 		ENST00000361727, 
ENST00000463592, ENST00000538075, 
Fusion gene scores* DoF score14 X 8 X 9=100830 X 34 X 9=9180
# samples 1636
** MAII scorelog2(16/1008*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(36/9180*10)=-4.6724253419715
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GALNT11 [Title/Abstract] AND CNTNAP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGALNT11(151722969)-CNTNAP2(147259230), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGALNT11

GO:0018243

protein O-linked glycosylation via threonine

24226769


check buttonFusion gene breakpoints across GALNT11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CNTNAP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4CESCTCGA-ZJ-AAXB-01AGALNT11chr7

151722969

-CNTNAP2chr7

147259230

+
ChimerDB4CESCTCGA-ZJ-AAXB-01AGALNT11chr7

151722969

+CNTNAP2chr7

147259230

+


Top

Fusion Gene ORF analysis for GALNT11-CNTNAP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000482812ENST00000361727GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
3UTR-intronENST00000482812ENST00000463592GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
3UTR-intronENST00000482812ENST00000538075GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
5CDS-intronENST00000452146ENST00000463592GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
5CDS-intronENST00000452146ENST00000538075GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
5UTR-3CDSENST00000430044ENST00000361727GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
5UTR-intronENST00000430044ENST00000463592GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
5UTR-intronENST00000430044ENST00000538075GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
In-frameENST00000452146ENST00000361727GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-3CDSENST00000320311ENST00000361727GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-3CDSENST00000415421ENST00000361727GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-3CDSENST00000422997ENST00000361727GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-3CDSENST00000434507ENST00000361727GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000320311ENST00000463592GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000320311ENST00000538075GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000415421ENST00000463592GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000415421ENST00000538075GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000422997ENST00000463592GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000422997ENST00000538075GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000434507ENST00000463592GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+
intron-intronENST00000434507ENST00000538075GALNT11chr7

151722969

+CNTNAP2chr7

147259230

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000452146GALNT11chr7151722969+ENST00000361727CNTNAP2chr7147259230+773513472352781

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000452146ENST00000361727GALNT11chr7151722969+CNTNAP2chr7147259230+0.0003997810.99960023

Top

Fusion Genomic Features for GALNT11-CNTNAP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GALNT11chr7151722969+CNTNAP2chr7147259229+4.99E-081
GALNT11chr7151722969+CNTNAP2chr7147259229+4.99E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for GALNT11-CNTNAP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:151722969/chr7:147259230)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CNTNAP2

Q9UHC6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. {ECO:0000250|UniProtKB:Q9CPW0, ECO:0000305|PubMed:33238150}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCNTNAP2chr7:151722969chr7:147259230ENST0000036172710241055_12145921332.0DomainLaminin G-like 4
TgeneCNTNAP2chr7:151722969chr7:147259230ENST000003617271024592_7985921332.0DomainFibrinogen C-terminal
TgeneCNTNAP2chr7:151722969chr7:147259230ENST000003617271024799_9635921332.0DomainLaminin G-like 3
TgeneCNTNAP2chr7:151722969chr7:147259230ENST000003617271024963_10025921332.0DomainEGF-like 2
TgeneCNTNAP2chr7:151722969chr7:147259230ENST0000036172710241284_13315921332.0Topological domainCytoplasmic
TgeneCNTNAP2chr7:151722969chr7:147259230ENST0000036172710241263_12835921332.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGALNT11chr7:151722969chr7:147259230ENST00000320311+112476_6070609.0DomainRicin B-type lectin
HgeneGALNT11chr7:151722969chr7:147259230ENST00000415421+15476_6070203.0DomainRicin B-type lectin
HgeneGALNT11chr7:151722969chr7:147259230ENST00000430044+112476_6070609.0DomainRicin B-type lectin
HgeneGALNT11chr7:151722969chr7:147259230ENST00000434507+114476_6070609.0DomainRicin B-type lectin
HgeneGALNT11chr7:151722969chr7:147259230ENST00000320311+112150_2610609.0RegionNote=Catalytic subdomain A
HgeneGALNT11chr7:151722969chr7:147259230ENST00000320311+112319_3810609.0RegionNote=Catalytic subdomain B
HgeneGALNT11chr7:151722969chr7:147259230ENST00000415421+15150_2610203.0RegionNote=Catalytic subdomain A
HgeneGALNT11chr7:151722969chr7:147259230ENST00000415421+15319_3810203.0RegionNote=Catalytic subdomain B
HgeneGALNT11chr7:151722969chr7:147259230ENST00000430044+112150_2610609.0RegionNote=Catalytic subdomain A
HgeneGALNT11chr7:151722969chr7:147259230ENST00000430044+112319_3810609.0RegionNote=Catalytic subdomain B
HgeneGALNT11chr7:151722969chr7:147259230ENST00000434507+114150_2610609.0RegionNote=Catalytic subdomain A
HgeneGALNT11chr7:151722969chr7:147259230ENST00000434507+114319_3810609.0RegionNote=Catalytic subdomain B
HgeneGALNT11chr7:151722969chr7:147259230ENST00000320311+1121_60609.0Topological domainCytoplasmic
HgeneGALNT11chr7:151722969chr7:147259230ENST00000320311+11230_6080609.0Topological domainLumenal
HgeneGALNT11chr7:151722969chr7:147259230ENST00000415421+151_60203.0Topological domainCytoplasmic
HgeneGALNT11chr7:151722969chr7:147259230ENST00000415421+1530_6080203.0Topological domainLumenal
HgeneGALNT11chr7:151722969chr7:147259230ENST00000430044+1121_60609.0Topological domainCytoplasmic
HgeneGALNT11chr7:151722969chr7:147259230ENST00000430044+11230_6080609.0Topological domainLumenal
HgeneGALNT11chr7:151722969chr7:147259230ENST00000434507+1141_60609.0Topological domainCytoplasmic
HgeneGALNT11chr7:151722969chr7:147259230ENST00000434507+11430_6080609.0Topological domainLumenal
HgeneGALNT11chr7:151722969chr7:147259230ENST00000320311+1127_290609.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGALNT11chr7:151722969chr7:147259230ENST00000415421+157_290203.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGALNT11chr7:151722969chr7:147259230ENST00000430044+1127_290609.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneGALNT11chr7:151722969chr7:147259230ENST00000434507+1147_290609.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCNTNAP2chr7:151722969chr7:147259230ENST000003617271024216_3685921332.0DomainLaminin G-like 1
TgeneCNTNAP2chr7:151722969chr7:147259230ENST000003617271024401_5525921332.0DomainLaminin G-like 2
TgeneCNTNAP2chr7:151722969chr7:147259230ENST000003617271024554_5915921332.0DomainEGF-like 1
TgeneCNTNAP2chr7:151722969chr7:147259230ENST00000361727102428_12625921332.0Topological domainExtracellular


Top

Fusion Gene Sequence for GALNT11-CNTNAP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>32220_32220_1_GALNT11-CNTNAP2_GALNT11_chr7_151722969_ENST00000452146_CNTNAP2_chr7_147259230_ENST00000361727_length(transcript)=7735nt_BP=134nt
GCGACGCCTGGCTGCTGGGCCCCGGGGCAGTTCAGCCCGCGCCGCTCCTGCGGGTCGGACTGGGGCTGTGGCGGGAGAGAAGATGCCGCA
GCCCGAGTCCCAGAAGGCGGCGATCCTGGGCTGCGGGCAAGGCGCTATCTACGAGCCTTCCTGTGAAGCCTACAAACACCTAGGACAGAC
ATCAAATTATTACTGGATAGATCCTGATGGCAGCGGACCTCTGGGGCCTCTGAAAGTTTACTGCAACATGACAGAGGACAAAGTGTGGAC
CATAGTGTCTCATGACTTGCAGATGCAGACGCCTGTGGTCGGCTACAACCCAGAAAAATACTCAGTGACACAGCTCGTTTACAGCGCCTC
CATGGACCAGATAAGTGCCATCACTGACAGTGCCGAGTACTGCGAGCAGTATGTCTCCTATTTCTGCAAGATGTCAAGATTGTTGAACAC
CCCAGATGGAAGCCCTTACACTTGGTGGGTTGGCAAAGCCAACGAGAAGCACTACTACTGGGGAGGCTCTGGGCCTGGAATCCAGAAATG
TGCCTGCGGCATCGAACGCAACTGCACAGATCCCAAGTACTACTGTAACTGCGACGCGGACTACAAGCAATGGAGGAAGGATGCTGGTTT
CTTATCATACAAAGATCACCTGCCAGTGAGCCAAGTGGTGGTTGGAGATACTGACCGTCAAGGCTCAGAAGCCAAATTGAGCGTAGGTCC
TCTGCGCTGCCAAGGAGACAGGAATTATTGGAATGCCGCCTCTTTCCCAAACCCATCCTCCTACCTGCACTTCTCTACTTTCCAAGGGGA
AACTAGCGCTGACATTTCTTTCTACTTCAAAACATTAACCCCCTGGGGAGTGTTTCTTGAAAATATGGGAAAGGAAGATTTCATCAAGCT
GGAGCTGAAGTCTGCCACAGAAGTGTCCTTTTCATTTGATGTGGGAAATGGGCCAGTAGAGATTGTAGTGAGGTCACCAACCCCTCTCAA
CGATGACCAGTGGCACCGGGTCACTGCAGAGAGGAATGTCAAGCAGGCCAGCCTACAGGTGGACCGGCTACCGCAGCAGATCCGCAAGGC
CCCAACAGAAGGCCACACCCGCCTGGAGCTCTACAGCCAGTTATTTGTGGGTGGTGCTGGGGGCCAGCAGGGCTTCCTGGGCTGCATCCG
CTCCTTGAGGATGAATGGGGTGACACTTGACCTGGAGGAAAGAGCAAAGGTCACATCTGGGTTCATATCCGGATGCTCGGGCCATTGCAC
CAGCTATGGAACAAACTGTGAAAATGGAGGCAAATGCCTAGAGAGATACCACGGTTACTCCTGCGATTGCTCTAATACTGCATATGATGG
AACATTTTGCAACAAAGATGTTGGTGCATTTTTTGAAGAAGGGATGTGGCTACGATATAACTTTCAGGCACCAGCAACAAATGCCAGAGA
CTCCAGCAGCAGAGTAGACAACGCTCCCGACCAGCAGAACTCCCACCCGGACCTGGCACAGGAGGAGATCCGCTTCAGCTTCAGCACCAC
CAAGGCGCCCTGCATTCTCCTCTACATCAGCTCCTTCACCACAGACTTCTTGGCAGTCCTCGTCAAACCCACTGGAAGCTTACAGATTCG
ATACAACCTGGGTGGCACCCGAGAGCCATACAATATTGACGTAGACCACAGGAACATGGCCAATGGACAGCCCCACAGTGTCAACATCAC
CCGCCACGAGAAGACCATCTTTCTCAAGCTCGATCATTATCCTTCTGTGAGTTACCATCTGCCAAGTTCATCCGACACCCTCTTCAATTC
TCCCAAGTCGCTCTTTCTGGGAAAAGTTATAGAAACAGGGAAAATTGACCAAGAGATTCACAAATACAACACCCCAGGATTCACTGGTTG
CCTCTCCAGAGTCCAGTTCAACCAGATCGCCCCTCTCAAGGCCGCCTTGAGGCAGACAAACGCCTCGGCTCACGTCCACATCCAGGGCGA
GCTGGTGGAGTCCAACTGCGGGGCCTCGCCGCTGACCCTCTCCCCCATGTCGTCCGCCACCGACCCCTGGCACCTGGATCACCTGGATTC
AGCCAGTGCGGATTTTCCATATAATCCAGGACAAGGCCAAGCTATAAGAAATGGAGTCAACAGAAACTCGGCTATCATTGGAGGCGTCAT
TGCTGTGGTGATTTTCACCATCCTGTGCACCCTGGTCTTCCTGATCCGGTACATGTTCCGCCACAAGGGCACCTACCATACCAACGAAGC
AAAGGGGGCGGAGTCGGCAGAGAGCGCGGACGCCGCCATCATGAACAACGACCCCAACTTCACAGAGACCATTGATGAAAGCAAAAAGGA
ATGGCTCATTTGAGGGGTGGCTACTTGGCTATGGGATAGGGAGGAGGGAATTACTAGGGAGGAGAGAAAGGGACAAAAGCACCCTGCTTC
ATACTCTTGAGCACATCCTTAAAATATCAGCACAAGTTGGGGGAGGCAGGCAATGGAATATAATGGAATATTCTTGAGACTGATCACAAA
AAAAAAAACCTTTTTAATATTTCTTTATAGCTGAGTTTTCCCTTCTGTATCAAAACAAAATAATACAAAAAATGCTTTTAGAGTTTAAGC
AATGGTTGAAATTTGTAGGTACTATCTGTCTTATTTTGTGTGTGTTTAGAGGTGTTCTAAAGACCCGTGGTAACAGGGCAAGTTTTCTAC
GTTTTTAAGAGCCCTTAGAACGTGGGTATTTTTTTTCTTGAGAAAAGCTAATGCACCTACAGATGGCCCCCAACATTCTCTTCCTTTTGC
TTCTAGTCAACCTTAATGGGCTGTTACAGAAACTAGTTCGTGTTTATATACTATTTCCTTTGATGTCCTATAAGTCGGAAAAGAAAGGGG
CAAAGAGAACCTATTATTTGCCAGTTTTTAAGCAGAGCTCAATCTATGCCAGCTCTCTGGCATCTGGGGTTCCTGACTGATACCAGCAGT
TGAAGGAAGAGAGTGCATGGCACCTGGTGTGTAACGACACAATCAGCACAACTGGAGAGAGGCATTAAAGAACCAGGGAAGGTAGTTTGA
TTTTTCATTGAATTCTACAAGCTAATATTGTTCCACGTATGTAGTCTTAGACCAATAGCTGTAACTATCAGCTGCAATACCATGGTGACC
AGCTGTTACAAAAGATTTTTTCCTGTTTTATCTGAAACATACTGGATTTATATATGTATAAGCGCCTCAATGGGGAATTAGAGCCAGATG
TTATGATTTGTTTGCTCTTTTTCTTTTATAGTTTAGTTATAGCAAAAATATGGATAATTTCTAGTGAATGCATAAATTAGGTTGCGTTTC
TTATTTTGCTTTAAATCTCTGGTAGTTTTTCCACCCCTGTGACACAATCCTAATAGACAGTGTCCTGTAAATGGACACAACACAATAAAG
TCAAGTTATTATTGCTGTTACTCTGGATGATATGGAAAACACTGCCATATTTTAAATCAACTACTCCACGTGTTTTTCCATCCAATCACA
CTGCTGTGATTCAGGGATCTTTCTTCTAAGACGGACACATTTGAACCTCAGGTTCATCACAAACCTGGTACCTGTTGCTTCCCAGAGGAT
GGAGAAGTGTAGTTAATCACACCTCTTAGTTTAATCTGAAATCTTGACCCAGTTATTTAACAAATAAATACCTCATTGATTATATTTAAA
AGTAATACACTTCCTGTAAACAAATGGGGACAATGCATCCAAAAAATCTTTTTAAACAGATTACACAAAAATTATTTCCAGAAAGGCTAC
CATTTATCATCATTATATTTCAAGCCTCTTATACTTAATAAGCACTTTCTAAAAAGTCTTGAGATCCCACCATTCTGAGGAATTCAATAT
GATCACTTTTTCCTTCTTTGCCTGGGAGAGGTTAAGAGGAGGTTTCGAAGGTATAGATGCTATTGTTCTGATGGCCCGGCTGAATAAAAT
GGAAATTCTAGTTTGTTAGAATTATGCATTCTTTTTCAAGATTCTCAGTGTGCCTAACTTATTGGAGCACATCAGTTTCTTGGGTAATGG
AAAACATTACCTAGAGTTGCCAGTGGCACATTACACCAGTACAGAGCACATTCCAAAGGAGACATTGGACCAGTTAATTCCCATACAAGT
CAAGGTAACAGAACAAAAGGGAATCCTGATGCCCTTTTACCATTGCTGGTTGAGCTCAGGCACTGTCATGGACACCCTTAATTTTAAAAG
GTTTTAATCATTCTTCTATAAAATACATTTAAAATGGAAAAATACTTAATATCACTAAATATCAGAACAATGTAACATTTACAAATGACA
TATTGAAAGCAAAGGCTGTTTTATTTAGCCAAGATGATTACCATTAGGAGTTACTTTATGTATTGTTGAAAGCAAATTTTAAACATGATG
TTTTAGAAGTGTTTCTGATTTTTAAACCTGGTTTACAGGTATTACTTCTGCACTTACCAAATAATGCCAGATGGAAATTTATTATTTCTT
GCAATTCCCATGATAGCTCTGTTCTTTATGCATTGTCTCAACACTTTCCCTTTTTTCCCAAAATGAGTAGAGAATTAAAGCCACCCAAAA
CAGCTTCTGCTACTAAAATGTTCTCATCCTTTCTCCTCCCTCTCCTTTTCCTGCCACAAAAGGTGAAAAATGAGATCCAATCCTCTCACC
AAAATTTCAAACCTAGGACACTGGAATGACTGCAGGGATCAGTGGTTCTCCCATATCACCATCAATTAAGACATATAGGACACTGTCTTC
CTTCAAGAGGGTTACAATGTGGCCATCAGACAGGAAACCAAACGGTGGATAAAGTATTAAGTAACTAAGTGCCAAATAAATGCTGGAAAT
CTTGACCTCTCCTTGGGATTATGGGTGTAACAAAAATCCCTACATCTGTTTATGAAGGCCATATTCAGTACATTTTAAATGGTAAATAAT
CTGTTTATGTGAAGAAAAAGAATTAAGTCTTTCTTCCAACTCTCTCCTTGGATAGCCTAGCACAGTGCAGCCTCCATAACCATGACATTC
CCGCCCAAGCTCTCAGTGCCTAATCCTGCTTTGTCATTCACATCTCACAAAATCTTGACATCTTACATTCCAATACATTATCAAGCAAGC
ACAAGTATGCTGGTAGTAGCCTCTTTAAATAATATGTATAGACAACAACAACGACAAAAAATAGACTGTTTTAAAGTTTCAGGGAAAGTT
GGTGGCTGATTTAAAGTTGTGCAGGAAACATCTTCTGTGTATGAAGCAAATGTCGATGTTTTGAAAAAAGCTAGGAGATGACTTTGAATG
AATGCAAGGTTAGTGAGATCCTAAGCTCTCAAAATAGCATATTCCCTAGAGCTCAAGAAAGCTGGTCCAGGAGGTTGAAAAAGCTATTTT
GTTGTTAAATTATTTTCTGGCCCTTCTTAATATTTAAAAATGTATTTCCCCTTGTGGCTTTCAACCACCTGCTCAAAAAAAGAGACTTGT
TACATGAAAGTTTTCATTAAAGAGCTGAAAACAAGAATTTAGAGAGCCATTCCTAGAAAATGTCCTACTGCCCTGCATTTGACAAACAAG
CATCCTTTACTAACAAGAGCAGGAATTCAGAGGCACAAGAAAAAGCATTGGCATGAGCCAAAGAGTCTGTCTTAATGTTACTTTTGAAAA
TCTGCTGAGCGGCCACCATATGCAGGCTGAGAGCTGGGCACAGGCGAAGCCATTGGAAGCACTTCAGGAACAAGCACACAGCTGTGGGAC
TTGAACATGCAAGTGTTCAGGTTGTGTCAAGAAGCTTTTCTTTCCTTCTATGATGGAATCTGTTCTTTTCTATCCTACTTTTTTCTCTCT
TCCTCTCCTCACCACATTATACCCTGCTCTTACGCAGTAAACGTTTTAATGGCCCGTTTATGTCTCATGCCTCCAAACAACACTGAATTT
GAAACCCCCCATTTTTTCTTTTCACCACCCTGTTGAGCAATTTTCCCAAAAAAAGGGCAGCAATTATTAAATTGAATTCAAGTAAGCCAG
CCAAAGATAGGTCCTAAATTGCTAGTCCCAGTAGAACCACCTGATCCTAAACCAGTGCGAAACAAACAGTAACAATGTCCCCAGCTGACT
TCAGCTAAGAACCAATGGCTCCTACCCCCGCCCCGCTTTTTTTTGTTGTTTTTTGTTTTGTTTTGAGACGGAGTCTTGCTCTGTCCCCCA
GGCTGGAGTGCACTGGCGCAATCTCGGGCTCACTGCAACCTCCTCCTCCTCCCACATTGAGGCGATTCTCCTGCCTCAGCCTCCCAAGTA
GCTGGGATTACAGGCACCCGCCATCACACCCAGCTAATTTTTTTTTTTTTTTGTATTATTAGTAGAAGCCAGGTTTCACCATGTTGGCCA
GGGTGGTCTCGAACTCCTGACCTCAAGTGATCCGTCCACCTCGGCCTTGCAAATTGCTGGGATTACAGGTGTGAGCCACCGTGCCGAGCC
AGCCCCATTTTTTAAATGATGTTTTGGTTAAGAGTGGACCATGAGAATTAGCTGACAGCATCCCCTTTCTCTCTCCCTGCCTTGGTGGGA
CCCTCCCTGTGTGACCTTGGTCAAGTCCTCGAACTTTTGTCCCGTATTTAAGATGGAGCTGTTTTACCTACTTCATAAGACAGTTGCGAG
GTGCCATTGATTCTTGACTGCAAAATACCTTGAAACCCTTATATAAAGACTGAAGTCAACGGAGCCTAGTGAAAGACTTACTTTGTGGCT
TGTGGTTGAAAGTCACATCAAAAGACAAATGTGGCCACGTTCAGGAATTGGAGACTTACTGGCATGGCTCTACAGCTGCTCAGTTATTAA
TCATGCAGACTAACCTGTCAACACTGGGAGATGCAACATAGCAAAAGGACAGAGAAATTAGAATTTTTTGTGCAGAAAGCCCTAAATTCC
CACCTGAATGTAACTTACAGCTCCCTTACCTACTCTCACACATGCCCTCAAACATGCTAGATTGGCTTATACATAGGCCAACACAAAATA
CAAACGTGACGTGTTCATGTAGCCTAGTGGCTATATGCCTATTCTCCATGTACCCTGCATGGTAGTGCTGCAAACTTTAAAGTACATTTC
TTTCACAGCAGTATTTTTTTTCATAAGTGGCATATAAATGTCATTCAATGAAATGGGGAAATCACGTTGAGAAGTTGGTCTGTCATCTCC
CATTGAGCAAAGACTGGCAGGAGATAATAAAAATAAATATGGGCACACATGTATTAATATACAGCACGCATTTACAAGTTTATTTTCCAG
ATAAAATTGTGCTATAAGAACAGCTCTACCAAGACAGTCTGCACCATTTCCAAGTCTCAGTTAATTTACAGCAACTGCTGCTTTCGGAGA
TGGCTGTGAAAATATGGAAGTTCCTCTCAAGTAGGCCAAGAAACAGTTCTAGATTTTACTAAGTTTTATTTTGTCAGGTTTTTTAAATTT
TTTCAGTGAGCGTGGTGACTGCAGAGGTTAGTGCTGTGAAAAGCTGGGCTAAATATTCTTTCTGTAAAGTCAAACAGGATTCCATCCCCT
GTGAAATAACACAAAATTTCACTCTCTAAAAGCAACAGCATGTAAACTAGAATGAAAGAAGGAAATTATGTACGTATGCCTAATATTCTT

>32220_32220_1_GALNT11-CNTNAP2_GALNT11_chr7_151722969_ENST00000452146_CNTNAP2_chr7_147259230_ENST00000361727_length(amino acids)=781AA_BP=42
MAAGPRGSSARAAPAGRTGAVAGEKMPQPESQKAAILGCGQGAIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIV
SHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCAC
GIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETS
ADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPT
EGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTF
CNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYN
LGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLS
RVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GALNT11-CNTNAP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for GALNT11-CNTNAP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for GALNT11-CNTNAP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource