FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:GANC-AP2S1 (FusionGDB2 ID:32348)

Fusion Gene Summary for GANC-AP2S1

check button Fusion gene summary
Fusion gene informationFusion gene name: GANC-AP2S1
Fusion gene ID: 32348
HgeneTgene
Gene symbol

GANC

AP2S1

Gene ID

2595

1175

Gene nameglucosidase alpha, neutral Cadaptor related protein complex 2 subunit sigma 1
Synonyms-AP17|CLAPS2|FBH3|FBHOk|HHC3
Cytomap

15q15.1

19q13.32

Type of geneprotein-codingprotein-coding
Descriptionneutral alpha-glucosidase CAP-2 complex subunit sigmaHA2 17 kDa subunitadaptor protein complex AP-2 subunit sigmaadaptor related protein complex 2 sigma 1 subunitclathrin assembly protein 2 sigma small chainclathrin coat assembly protein AP17clathrin coat-associated protein A
Modification date2020031320200327
UniProtAcc.

P53680

Ensembl transtripts involved in fusion geneENST00000318010, ENST00000566442, 
ENST00000440615, 		ENST00000601649, 
ENST00000263270, ENST00000352203, 
ENST00000593442, ENST00000597020, 
ENST00000599990, ENST00000601498, 
Fusion gene scores* DoF score6 X 6 X 5=1804 X 3 X 3=36
# samples 65
** MAII scorelog2(6/180*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/36*10)=0.473931188332412
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: GANC [Title/Abstract] AND AP2S1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGANC(42602661)-AP2S1(47342835), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across GANC (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AP2S1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-30-1861GANCchr15

42602661

+AP2S1chr19

47342835

-


Top

Fusion Gene ORF analysis for GANC-AP2S1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000318010ENST00000601649GANCchr15

42602661

+AP2S1chr19

47342835

-
5CDS-intronENST00000566442ENST00000601649GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000318010ENST00000263270GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000318010ENST00000352203GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000318010ENST00000593442GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000318010ENST00000597020GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000318010ENST00000599990GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000318010ENST00000601498GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000566442ENST00000263270GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000566442ENST00000352203GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000566442ENST00000593442GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000566442ENST00000597020GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000566442ENST00000599990GANCchr15

42602661

+AP2S1chr19

47342835

-
In-frameENST00000566442ENST00000601498GANCchr15

42602661

+AP2S1chr19

47342835

-
intron-3CDSENST00000440615ENST00000263270GANCchr15

42602661

+AP2S1chr19

47342835

-
intron-3CDSENST00000440615ENST00000352203GANCchr15

42602661

+AP2S1chr19

47342835

-
intron-3CDSENST00000440615ENST00000593442GANCchr15

42602661

+AP2S1chr19

47342835

-
intron-3CDSENST00000440615ENST00000597020GANCchr15

42602661

+AP2S1chr19

47342835

-
intron-3CDSENST00000440615ENST00000599990GANCchr15

42602661

+AP2S1chr19

47342835

-
intron-3CDSENST00000440615ENST00000601498GANCchr15

42602661

+AP2S1chr19

47342835

-
intron-intronENST00000440615ENST00000601649GANCchr15

42602661

+AP2S1chr19

47342835

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000566442GANCchr1542602661+ENST00000352203AP2S1chr1947342835-219116046711705344
ENST00000566442GANCchr1542602661+ENST00000601498AP2S1chr1947342835-216916046711879402
ENST00000566442GANCchr1542602661+ENST00000599990AP2S1chr1947342835-216916046711879402
ENST00000566442GANCchr1542602661+ENST00000593442AP2S1chr1947342835-216916046711879402
ENST00000566442GANCchr1542602661+ENST00000263270AP2S1chr1947342835-216016046711879402
ENST00000566442GANCchr1542602661+ENST00000597020AP2S1chr1947342835-215516046711879402
ENST00000318010GANCchr1542602661+ENST00000352203AP2S1chr1947342835-173011432101244344
ENST00000318010GANCchr1542602661+ENST00000601498AP2S1chr1947342835-170811432101418402
ENST00000318010GANCchr1542602661+ENST00000599990AP2S1chr1947342835-170811432101418402
ENST00000318010GANCchr1542602661+ENST00000593442AP2S1chr1947342835-170811432101418402
ENST00000318010GANCchr1542602661+ENST00000263270AP2S1chr1947342835-169911432101418402
ENST00000318010GANCchr1542602661+ENST00000597020AP2S1chr1947342835-169411432101418402

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000566442ENST00000352203GANCchr1542602661+AP2S1chr1947342835-0.0016637860.99833626
ENST00000566442ENST00000601498GANCchr1542602661+AP2S1chr1947342835-0.0010127690.99898726
ENST00000566442ENST00000599990GANCchr1542602661+AP2S1chr1947342835-0.0010127690.99898726
ENST00000566442ENST00000593442GANCchr1542602661+AP2S1chr1947342835-0.0010127690.99898726
ENST00000566442ENST00000263270GANCchr1542602661+AP2S1chr1947342835-0.0010111740.9989888
ENST00000566442ENST00000597020GANCchr1542602661+AP2S1chr1947342835-0.0009832430.99901676
ENST00000318010ENST00000352203GANCchr1542602661+AP2S1chr1947342835-0.001736260.9982638
ENST00000318010ENST00000601498GANCchr1542602661+AP2S1chr1947342835-0.0010522060.9989478
ENST00000318010ENST00000599990GANCchr1542602661+AP2S1chr1947342835-0.0010522060.9989478
ENST00000318010ENST00000593442GANCchr1542602661+AP2S1chr1947342835-0.0010522060.9989478
ENST00000318010ENST00000263270GANCchr1542602661+AP2S1chr1947342835-0.0010402080.9989598
ENST00000318010ENST00000597020GANCchr1542602661+AP2S1chr1947342835-0.001006150.9989938

Top

Fusion Genomic Features for GANC-AP2S1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for GANC-AP2S1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:42602661/chr19:47342835)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AP2S1

P53680

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif (By similarity). May also play a role in extracellular calcium homeostasis. {ECO:0000250, ECO:0000269|PubMed:14745134, ECO:0000269|PubMed:15473838, ECO:0000269|PubMed:19033387, ECO:0000269|PubMed:23222959}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

Fusion Gene Sequence for GANC-AP2S1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>32348_32348_1_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000263270_length(transcript)=1699nt_BP=1143nt
ATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAAGATTTGTCACT
CCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAATCGGCTTTTTTA
AAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAGAGGAAATAAGT
CTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGCTTTCCAAGAAG
TCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTAAGGTTCCTCTC
CTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTGAAGTTCCGGAT
GTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAAAAGGAGACCTG
AAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGGGCCAATTATAC
TTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGGAAAATCAAGAA
GATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATTTCTCCTTGCAT
GGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACCGTCTTTATAAC
CTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGGGCAGAACTATA
GGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGATCATTTACCGC
CGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACTTCGTGGAGGTC
TTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGATGTTCCTGGCT
GGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGAGCCCCACCCCG
GCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTGCCTAGGAGGAA
GGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCACCGTGTGTGTCC

>32348_32348_1_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000263270_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_2_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000352203_length(transcript)=1730nt_BP=1143nt
ATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAAGATTTGTCACT
CCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAATCGGCTTTTTTA
AAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAGAGGAAATAAGT
CTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGCTTTCCAAGAAG
TCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTAAGGTTCCTCTC
CTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTGAAGTTCCGGAT
GTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAAAAGGAGACCTG
AAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGGGCCAATTATAC
TTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGGAAAATCAAGAA
GATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATTTCTCCTTGCAT
GGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACCGTCTTTATAAC
CTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGGGCAGAACTATA
GGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGGTTTACACGGTCGTGGACGAGATGTTC
CTGGCTGGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGAGCCCC
ACCCCGGCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTGCCTAG
GAGGAAGGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCACCGTGT
GTGTCCCGAGTAACCGTGCCGTTGTCGTGTGATGCCATAAGCGTCTGTGCGTGGAGTCCCCAATAAACCTGTGGTCCTGCCTGGCCTTGC
CGTCTTTGAGCCCTTGCCTGTCTCCCGTCTTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGTTCC
GGAACTTTAAGATCATTTACCGCCGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGG

>32348_32348_2_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000352203_length(amino acids)=344AA_BP=
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD

--------------------------------------------------------------
>32348_32348_3_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000593442_length(transcript)=1708nt_BP=1143nt
ATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAAGATTTGTCACT
CCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAATCGGCTTTTTTA
AAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAGAGGAAATAAGT
CTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGCTTTCCAAGAAG
TCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTAAGGTTCCTCTC
CTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTGAAGTTCCGGAT
GTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAAAAGGAGACCTG
AAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGGGCCAATTATAC
TTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGGAAAATCAAGAA
GATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATTTCTCCTTGCAT
GGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACCGTCTTTATAAC
CTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGGGCAGAACTATA
GGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGATCATTTACCGC
CGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACTTCGTGGAGGTC
TTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGATGTTCCTGGCT
GGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGAGCCCCACCCCG
GCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTGCCTAGGAGGAA
GGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCACCGTGTGTGTCC

>32348_32348_3_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000593442_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_4_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000597020_length(transcript)=1694nt_BP=1143nt
ATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAAGATTTGTCACT
CCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAATCGGCTTTTTTA
AAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAGAGGAAATAAGT
CTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGCTTTCCAAGAAG
TCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTAAGGTTCCTCTC
CTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTGAAGTTCCGGAT
GTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAAAAGGAGACCTG
AAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGGGCCAATTATAC
TTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGGAAAATCAAGAA
GATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATTTCTCCTTGCAT
GGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACCGTCTTTATAAC
CTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGGGCAGAACTATA
GGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGATCATTTACCGC
CGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACTTCGTGGAGGTC
TTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGATGTTCCTGGCT
GGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGAGCCCCACCCCG
GCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTGCCTAGGAGGAA
GGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCACCGTGTGTGTCC

>32348_32348_4_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000597020_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_5_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000599990_length(transcript)=1708nt_BP=1143nt
ATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAAGATTTGTCACT
CCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAATCGGCTTTTTTA
AAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAGAGGAAATAAGT
CTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGCTTTCCAAGAAG
TCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTAAGGTTCCTCTC
CTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTGAAGTTCCGGAT
GTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAAAAGGAGACCTG
AAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGGGCCAATTATAC
TTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGGAAAATCAAGAA
GATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATTTCTCCTTGCAT
GGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACCGTCTTTATAAC
CTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGGGCAGAACTATA
GGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGATCATTTACCGC
CGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACTTCGTGGAGGTC
TTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGATGTTCCTGGCT
GGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGAGCCCCACCCCG
GCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTGCCTAGGAGGAA
GGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCACCGTGTGTGTCC

>32348_32348_5_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000599990_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_6_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000601498_length(transcript)=1708nt_BP=1143nt
ATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAAGATTTGTCACT
CCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAATCGGCTTTTTTA
AAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAGAGGAAATAAGT
CTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGCTTTCCAAGAAG
TCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTAAGGTTCCTCTC
CTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTGAAGTTCCGGAT
GTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAAAAGGAGACCTG
AAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGGGCCAATTATAC
TTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGGAAAATCAAGAA
GATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATTTCTCCTTGCAT
GGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACCGTCTTTATAAC
CTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGGGCAGAACTATA
GGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGATCATTTACCGC
CGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACTTCGTGGAGGTC
TTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGATGTTCCTGGCT
GGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGAGCCCCACCCCG
GCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTGCCTAGGAGGAA
GGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCACCGTGTGTGTCC

>32348_32348_6_GANC-AP2S1_GANC_chr15_42602661_ENST00000318010_AP2S1_chr19_47342835_ENST00000601498_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_7_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000263270_length(transcript)=2160nt_BP=1604nt
TTTTCTGTCTCCCAGCCGTTAAAGGTTTTAGGACCAGGCAGGCACCCCGTGCAGGATTTGGCTCTCTACTTCCGCTCGCCCCAGCCCTTC
ATCCCTTCTAAGTCAATGTCAGACTTTGGGGCCAGAAAGTCTGGAAAAGCCCTAAGCCTGGCTGCCCAAGTGGCGTCTAGTAGTGAGTTC
TCCGGTTTGGGTGGTATTTAAGCAAAGGCTGGAATTCGGCGGTGGTGGAGTACACGCGATTCCTAGACTGGGTAGTGTAACAACCTTCAA
AGGCCCCTTCTAGCCCTGAAGAGTACGATGCTGCAGTACAATCTGGCTGGAGACCTAGCCTCCAGCAAAGACCCGGCCGGCACTTCCCAC
CCTTAACCGAAAACGGAGACAGAGAGGGACTCATTGCGTACACGCCCTCACCGCCGCCCAGTTTCGGTTCCTAACAAAAGCACGTTCCTC
ATCAGCCACCCATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAA
GATTTGTCACTCCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAAT
CGGCTTTTTTAAAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAG
AGGAAATAAGTCTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGC
TTTCCAAGAAGTCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTA
AGGTTCCTCTCCTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTG
AAGTTCCGGATGTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAA
AAGGAGACCTGAAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGG
GCCAATTATACTTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGG
AAAATCAAGAAGATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATT
TCTCCTTGCATGGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACC
GTCTTTATAACCTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGG
GCAGAACTATAGGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGA
TCATTTACCGCCGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACT
TCGTGGAGGTCTTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGA
TGTTCCTGGCTGGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGA
GCCCCACCCCGGCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTG
CCTAGGAGGAAGGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCAC
CGTGTGTGTCCCGAGTAACCGTGCCGTTGTCGTGTGATGCCATAAGCGTCTGTGCGTGGAGTCCCCAATAAACCTGTGGTCCTGCCTGGC

>32348_32348_7_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000263270_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_8_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000352203_length(transcript)=2191nt_BP=1604nt
TTTTCTGTCTCCCAGCCGTTAAAGGTTTTAGGACCAGGCAGGCACCCCGTGCAGGATTTGGCTCTCTACTTCCGCTCGCCCCAGCCCTTC
ATCCCTTCTAAGTCAATGTCAGACTTTGGGGCCAGAAAGTCTGGAAAAGCCCTAAGCCTGGCTGCCCAAGTGGCGTCTAGTAGTGAGTTC
TCCGGTTTGGGTGGTATTTAAGCAAAGGCTGGAATTCGGCGGTGGTGGAGTACACGCGATTCCTAGACTGGGTAGTGTAACAACCTTCAA
AGGCCCCTTCTAGCCCTGAAGAGTACGATGCTGCAGTACAATCTGGCTGGAGACCTAGCCTCCAGCAAAGACCCGGCCGGCACTTCCCAC
CCTTAACCGAAAACGGAGACAGAGAGGGACTCATTGCGTACACGCCCTCACCGCCGCCCAGTTTCGGTTCCTAACAAAAGCACGTTCCTC
ATCAGCCACCCATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAA
GATTTGTCACTCCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAAT
CGGCTTTTTTAAAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAG
AGGAAATAAGTCTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGC
TTTCCAAGAAGTCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTA
AGGTTCCTCTCCTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTG
AAGTTCCGGATGTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAA
AAGGAGACCTGAAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGG
GCCAATTATACTTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGG
AAAATCAAGAAGATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATT
TCTCCTTGCATGGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACC
GTCTTTATAACCTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGG
GCAGAACTATAGGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGGTTTACACGGTCGTGG
ACGAGATGTTCCTGGCTGGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGC
AGGCGAGCCCCACCCCGGCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCT
CAGCTGCCTAGGAGGAAGGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGA
GGCCACCGTGTGTGTCCCGAGTAACCGTGCCGTTGTCGTGTGATGCCATAAGCGTCTGTGCGTGGAGTCCCCAATAAACCTGTGGTCCTG
CCTGGCCTTGCCGTCTTTGAGCCCTTGCCTGTCTCCCGTCTTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTT
CTACAAGTTCCGGAACTTTAAGATCATTTACCGCCGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGC

>32348_32348_8_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000352203_length(amino acids)=344AA_BP=
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD

--------------------------------------------------------------
>32348_32348_9_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000593442_length(transcript)=2169nt_BP=1604nt
TTTTCTGTCTCCCAGCCGTTAAAGGTTTTAGGACCAGGCAGGCACCCCGTGCAGGATTTGGCTCTCTACTTCCGCTCGCCCCAGCCCTTC
ATCCCTTCTAAGTCAATGTCAGACTTTGGGGCCAGAAAGTCTGGAAAAGCCCTAAGCCTGGCTGCCCAAGTGGCGTCTAGTAGTGAGTTC
TCCGGTTTGGGTGGTATTTAAGCAAAGGCTGGAATTCGGCGGTGGTGGAGTACACGCGATTCCTAGACTGGGTAGTGTAACAACCTTCAA
AGGCCCCTTCTAGCCCTGAAGAGTACGATGCTGCAGTACAATCTGGCTGGAGACCTAGCCTCCAGCAAAGACCCGGCCGGCACTTCCCAC
CCTTAACCGAAAACGGAGACAGAGAGGGACTCATTGCGTACACGCCCTCACCGCCGCCCAGTTTCGGTTCCTAACAAAAGCACGTTCCTC
ATCAGCCACCCATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAA
GATTTGTCACTCCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAAT
CGGCTTTTTTAAAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAG
AGGAAATAAGTCTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGC
TTTCCAAGAAGTCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTA
AGGTTCCTCTCCTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTG
AAGTTCCGGATGTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAA
AAGGAGACCTGAAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGG
GCCAATTATACTTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGG
AAAATCAAGAAGATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATT
TCTCCTTGCATGGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACC
GTCTTTATAACCTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGG
GCAGAACTATAGGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGA
TCATTTACCGCCGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACT
TCGTGGAGGTCTTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGA
TGTTCCTGGCTGGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGA
GCCCCACCCCGGCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTG
CCTAGGAGGAAGGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCAC
CGTGTGTGTCCCGAGTAACCGTGCCGTTGTCGTGTGATGCCATAAGCGTCTGTGCGTGGAGTCCCCAATAAACCTGTGGTCCTGCCTGGC

>32348_32348_9_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000593442_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_10_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000597020_length(transcript)=2155nt_BP=1604nt
TTTTCTGTCTCCCAGCCGTTAAAGGTTTTAGGACCAGGCAGGCACCCCGTGCAGGATTTGGCTCTCTACTTCCGCTCGCCCCAGCCCTTC
ATCCCTTCTAAGTCAATGTCAGACTTTGGGGCCAGAAAGTCTGGAAAAGCCCTAAGCCTGGCTGCCCAAGTGGCGTCTAGTAGTGAGTTC
TCCGGTTTGGGTGGTATTTAAGCAAAGGCTGGAATTCGGCGGTGGTGGAGTACACGCGATTCCTAGACTGGGTAGTGTAACAACCTTCAA
AGGCCCCTTCTAGCCCTGAAGAGTACGATGCTGCAGTACAATCTGGCTGGAGACCTAGCCTCCAGCAAAGACCCGGCCGGCACTTCCCAC
CCTTAACCGAAAACGGAGACAGAGAGGGACTCATTGCGTACACGCCCTCACCGCCGCCCAGTTTCGGTTCCTAACAAAAGCACGTTCCTC
ATCAGCCACCCATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAA
GATTTGTCACTCCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAAT
CGGCTTTTTTAAAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAG
AGGAAATAAGTCTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGC
TTTCCAAGAAGTCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTA
AGGTTCCTCTCCTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTG
AAGTTCCGGATGTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAA
AAGGAGACCTGAAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGG
GCCAATTATACTTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGG
AAAATCAAGAAGATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATT
TCTCCTTGCATGGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACC
GTCTTTATAACCTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGG
GCAGAACTATAGGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGA
TCATTTACCGCCGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACT
TCGTGGAGGTCTTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGA
TGTTCCTGGCTGGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGA
GCCCCACCCCGGCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTG
CCTAGGAGGAAGGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCAC

>32348_32348_10_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000597020_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_11_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000599990_length(transcript)=2169nt_BP=1604nt
TTTTCTGTCTCCCAGCCGTTAAAGGTTTTAGGACCAGGCAGGCACCCCGTGCAGGATTTGGCTCTCTACTTCCGCTCGCCCCAGCCCTTC
ATCCCTTCTAAGTCAATGTCAGACTTTGGGGCCAGAAAGTCTGGAAAAGCCCTAAGCCTGGCTGCCCAAGTGGCGTCTAGTAGTGAGTTC
TCCGGTTTGGGTGGTATTTAAGCAAAGGCTGGAATTCGGCGGTGGTGGAGTACACGCGATTCCTAGACTGGGTAGTGTAACAACCTTCAA
AGGCCCCTTCTAGCCCTGAAGAGTACGATGCTGCAGTACAATCTGGCTGGAGACCTAGCCTCCAGCAAAGACCCGGCCGGCACTTCCCAC
CCTTAACCGAAAACGGAGACAGAGAGGGACTCATTGCGTACACGCCCTCACCGCCGCCCAGTTTCGGTTCCTAACAAAAGCACGTTCCTC
ATCAGCCACCCATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAA
GATTTGTCACTCCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAAT
CGGCTTTTTTAAAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAG
AGGAAATAAGTCTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGC
TTTCCAAGAAGTCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTA
AGGTTCCTCTCCTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTG
AAGTTCCGGATGTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAA
AAGGAGACCTGAAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGG
GCCAATTATACTTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGG
AAAATCAAGAAGATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATT
TCTCCTTGCATGGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACC
GTCTTTATAACCTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGG
GCAGAACTATAGGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGA
TCATTTACCGCCGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACT
TCGTGGAGGTCTTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGA
TGTTCCTGGCTGGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGA
GCCCCACCCCGGCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTG
CCTAGGAGGAAGGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCAC
CGTGTGTGTCCCGAGTAACCGTGCCGTTGTCGTGTGATGCCATAAGCGTCTGTGCGTGGAGTCCCCAATAAACCTGTGGTCCTGCCTGGC

>32348_32348_11_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000599990_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------
>32348_32348_12_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000601498_length(transcript)=2169nt_BP=1604nt
TTTTCTGTCTCCCAGCCGTTAAAGGTTTTAGGACCAGGCAGGCACCCCGTGCAGGATTTGGCTCTCTACTTCCGCTCGCCCCAGCCCTTC
ATCCCTTCTAAGTCAATGTCAGACTTTGGGGCCAGAAAGTCTGGAAAAGCCCTAAGCCTGGCTGCCCAAGTGGCGTCTAGTAGTGAGTTC
TCCGGTTTGGGTGGTATTTAAGCAAAGGCTGGAATTCGGCGGTGGTGGAGTACACGCGATTCCTAGACTGGGTAGTGTAACAACCTTCAA
AGGCCCCTTCTAGCCCTGAAGAGTACGATGCTGCAGTACAATCTGGCTGGAGACCTAGCCTCCAGCAAAGACCCGGCCGGCACTTCCCAC
CCTTAACCGAAAACGGAGACAGAGAGGGACTCATTGCGTACACGCCCTCACCGCCGCCCAGTTTCGGTTCCTAACAAAAGCACGTTCCTC
ATCAGCCACCCATAATCAAGACAAATTTGCCAAATAAATCATTGTAGAAACGCTAGTTTGGGCCTGAAAAATTCCAGGAGCAAGAGTCAA
GATTTGTCACTCCATGAGAATCTGGAGGGGACTCCCTTCCCAGAAACTTGACGATGAAGTACTGGTTGTAATTTTAGAAAGACACCCAAT
CGGCTTTTTTAAAAGATCGCCCAGGGCCCTTGTCCTGAGAGCTGGGAGCTGGTCGGAGTGACAGAGAAGCCATGGAAGCAGCAGTGAAAG
AGGAAATAAGTCTTGAAGATGAAGCTGTAGATAAAAACATTTTCAGAGACTGTAACAAGATCGCATTTTACAGGCGTCAGAAACAGTGGC
TTTCCAAGAAGTCCACCTATCAGGCATTATTGGATTCAGTCACAACAGATGAAGACAGCACCAGGTTCCAAATCATCAATGAAGCAAGTA
AGGTTCCTCTCCTGGCTGAAATTTATGGTATAGAAGGAAACATTTTCAGGCTTAAAATTAATGAAGAGACTCCTCTAAAACCCAGATTTG
AAGTTCCGGATGTCCTCACAAGCAAGCCAAGCACTGTAAGGCTGATTTCATGCTCTGGGGACACAGGCAGTCTGATATTGGCAGATGGAA
AAGGAGACCTGAAGTGCCATATCACAGCAAACCCATTCAAGGTAGACTTGGTGTCTGAAGAAGAGGTTGTGATTAGCATAAATTCCCTGG
GCCAATTATACTTTGAGCATCTACAGATTCTTCACAAACAAAGAGCTGCTAAAGAAAATGAGGAGGAGACATCAGTGGACACCTCTCAGG
AAAATCAAGAAGATCTGGGCCTGTGGGAAGAGAAATTTGGAAAATTTGTGGATATCAAAGCTAATGGCCCTTCTTCTATTGGTTTGGATT
TCTCCTTGCATGGATTTGAGCATCTTTATGGGATCCCACAACATGCAGAATCACACCAACTTAAAAATACTGGTGATGGAGATGCTTACC
GTCTTTATAACCTGGATGTCTATGGATACCAAATATATGATAAAATGGGCATTTATGGTTCAGTACCTTATCTCCTGGCCCACAAACTGG
GCAGAACTATAGGTATTTTCTGGCTGAATGCCTCGGAAACACTGGTGGAGATCAATACAGAGCCTGCAGTAGAGTTCCGGAACTTTAAGA
TCATTTACCGCCGCTATGCTGGCCTCTACTTCTGCATCTGTGTGGATGTCAATGACAACAACCTGGCTTACCTGGAGGCCATTCACAACT
TCGTGGAGGTCTTAAACGAATATTTCCACAATGTCTGTGAACTGGACCTGGTGTTCAACTTCTACAAGGTTTACACGGTCGTGGACGAGA
TGTTCCTGGCTGGCGAAATCCGAGAGACCAGCCAGACGAAGGTGCTGAAACAGCTGCTGATGCTACAGTCCCTGGAGTGAGGGCAGGCGA
GCCCCACCCCGGCCCCGGCCCCTCCTGGACTCGCCTGCTCGCTTCCCCTTCCCAGGCCCGTGGCCAACCCAGCAGTCCTTCCCTCAGCTG
CCTAGGAGGAAGGGACCCAGCTGGGTCTGGGCCACAAGGGAGGAGACTGCACCCCACTGCCTCTGGGCCCTGGCTGTGGGCAGAGGCCAC
CGTGTGTGTCCCGAGTAACCGTGCCGTTGTCGTGTGATGCCATAAGCGTCTGTGCGTGGAGTCCCCAATAAACCTGTGGTCCTGCCTGGC

>32348_32348_12_GANC-AP2S1_GANC_chr15_42602661_ENST00000566442_AP2S1_chr19_47342835_ENST00000601498_length(amino acids)=402AA_BP=311
MGAGRSDREAMEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGN
IFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQ
RAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYD
KMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GANC-AP2S1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for GANC-AP2S1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for GANC-AP2S1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource