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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GAPDH-TNC (FusionGDB2 ID:32420)

Fusion Gene Summary for GAPDH-TNC

check button Fusion gene summary
Fusion gene informationFusion gene name: GAPDH-TNC
Fusion gene ID: 32420
HgeneTgene
Gene symbol

GAPDH

TNC

Gene ID

2597

7134

Gene nameglyceraldehyde-3-phosphate dehydrogenasetroponin C1, slow skeletal and cardiac type
SynonymsG3PD|GAPD|HEL-S-162ePCMD1Z|CMH13|TN-C|TNC|TNNC
Cytomap

12p13.31

3p21.1

Type of geneprotein-codingprotein-coding
Descriptionglyceraldehyde-3-phosphate dehydrogenaseOCAS, p38 componentOct1 coactivator in S phase, 38 Kd componentaging-associated gene 9 proteinepididymis secretory sperm binding protein Li 162ePpeptidyl-cysteine S-nitrosylase GAPDHtroponin C, slow skeletal and cardiac musclescardiac troponin Cslow twitch skeletal/cardiac muscle troponin Ctroponin C type 1 (slow)
Modification date2020032720200313
UniProtAcc

P04406

.
Ensembl transtripts involved in fusion geneENST00000229239, ENST00000396856, 
ENST00000396858, ENST00000396859, 
ENST00000396861, 		ENST00000481475, 
ENST00000340094, ENST00000341037, 
ENST00000345230, ENST00000346706, 
ENST00000423613, ENST00000535648, 
ENST00000537320, ENST00000542877, 
ENST00000350763, 
Fusion gene scores* DoF score45 X 34 X 13=198908 X 8 X 4=256
# samples 5111
** MAII scorelog2(51/19890*10)=-5.28540221886225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/256*10)=-1.21864028647534
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GAPDH [Title/Abstract] AND TNC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGAPDH(6646176)-TNC(117783546), # samples:1
Anticipated loss of major functional domain due to fusion event.GAPDH-TNC seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
GAPDH-TNC seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
GAPDH-TNC seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGAPDH

GO:0010951

negative regulation of endopeptidase activity

22832495

HgeneGAPDH

GO:0017148

negative regulation of translation

23071094

HgeneGAPDH

GO:0031640

killing of cells of other organism

22832495

HgeneGAPDH

GO:0050715

positive regulation of cytokine secretion

22832495

HgeneGAPDH

GO:0050832

defense response to fungus

22832495

HgeneGAPDH

GO:0051873

killing by host of symbiont cells

22832495

HgeneGAPDH

GO:0052501

positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction

22832495

HgeneGAPDH

GO:0061844

antimicrobial humoral immune response mediated by antimicrobial peptide

22832495

HgeneGAPDH

GO:0071346

cellular response to interferon-gamma

15479637

TgeneTNC

GO:0006937

regulation of muscle contraction

18092822

TgeneTNC

GO:0060048

cardiac muscle contraction

25771144


check buttonFusion gene breakpoints across GAPDH (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TNC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CN-6024-01AGAPDHchr12

6646176

+TNCchr9

117783546

-


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Fusion Gene ORF analysis for GAPDH-TNC

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000229239ENST00000481475GAPDHchr12

6646176

+TNCchr9

117783546

-
5CDS-intronENST00000396856ENST00000481475GAPDHchr12

6646176

+TNCchr9

117783546

-
5CDS-intronENST00000396858ENST00000481475GAPDHchr12

6646176

+TNCchr9

117783546

-
5CDS-intronENST00000396859ENST00000481475GAPDHchr12

6646176

+TNCchr9

117783546

-
5CDS-intronENST00000396861ENST00000481475GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000340094GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000341037GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000345230GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000346706GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000423613GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000535648GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000537320GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000229239ENST00000542877GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000340094GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000341037GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000345230GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000346706GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000423613GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000535648GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000537320GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396856ENST00000542877GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000340094GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000341037GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000345230GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000346706GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000423613GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000535648GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000537320GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396858ENST00000542877GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000340094GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000341037GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000345230GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000346706GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000423613GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000535648GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000537320GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396859ENST00000542877GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000340094GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000341037GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000345230GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000346706GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000423613GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000535648GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000537320GAPDHchr12

6646176

+TNCchr9

117783546

-
Frame-shiftENST00000396861ENST00000542877GAPDHchr12

6646176

+TNCchr9

117783546

-
In-frameENST00000229239ENST00000350763GAPDHchr12

6646176

+TNCchr9

117783546

-
In-frameENST00000396856ENST00000350763GAPDHchr12

6646176

+TNCchr9

117783546

-
In-frameENST00000396858ENST00000350763GAPDHchr12

6646176

+TNCchr9

117783546

-
In-frameENST00000396859ENST00000350763GAPDHchr12

6646176

+TNCchr9

117783546

-
In-frameENST00000396861ENST00000350763GAPDHchr12

6646176

+TNCchr9

117783546

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000229239GAPDHchr126646176+ENST00000350763TNCchr9117783546-17279934891103204
ENST00000396856GAPDHchr126646176+ENST00000350763TNCchr9117783546-114941592472126
ENST00000396861GAPDHchr126646176+ENST00000350763TNCchr9117783546-1212478121588155
ENST00000396859GAPDHchr126646176+ENST00000350763TNCchr9117783546-114040679516145
ENST00000396858GAPDHchr126646176+ENST00000350763TNCchr9117783546-120046641523160

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000229239ENST00000350763GAPDHchr126646176+TNCchr9117783546-0.0071405980.9928595
ENST00000396856ENST00000350763GAPDHchr126646176+TNCchr9117783546-0.57299450.42700556
ENST00000396861ENST00000350763GAPDHchr126646176+TNCchr9117783546-0.0058751890.9941248
ENST00000396859ENST00000350763GAPDHchr126646176+TNCchr9117783546-0.0041730720.9958269
ENST00000396858ENST00000350763GAPDHchr126646176+TNCchr9117783546-0.04841380.9515862

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Fusion Genomic Features for GAPDH-TNC


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GAPDH-TNC


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:6646176/chr9:117783546)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GAPDH

P04406

.
FUNCTION: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. {ECO:0000250, ECO:0000269|PubMed:11724794, ECO:0000269|PubMed:23071094, ECO:0000269|PubMed:3170585}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGAPDHchr12:6646176chr9:117783546ENST00000229239+5913_14109336.0Nucleotide bindingNAD
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396858+4813_1467294.0Nucleotide bindingNAD
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396859+4813_14109336.0Nucleotide bindingNAD
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396861+5913_14109336.0Nucleotide bindingNAD
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241802_188818011838.0DomainFibronectin type-III 14
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241889_197718011838.0DomainFibronectin type-III 15
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241975_219018011838.0DomainFibrinogen C-terminal
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211533_162115281565.0DomainFibronectin type-III 11
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211622_171115281565.0DomainFibronectin type-III 12
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211712_180115281565.0DomainFibronectin type-III 13
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211802_188815281565.0DomainFibronectin type-III 14
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211889_197715281565.0DomainFibronectin type-III 15
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211975_219015281565.0DomainFibrinogen C-terminal
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221622_171116191656.0DomainFibronectin type-III 12
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221712_180116191656.0DomainFibronectin type-III 13
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221802_188816191656.0DomainFibronectin type-III 14
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221889_197716191656.0DomainFibronectin type-III 15
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221975_219016191656.0DomainFibrinogen C-terminal
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231712_180117101747.0DomainFibronectin type-III 13
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231802_188817101747.0DomainFibronectin type-III 14
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231889_197717101747.0DomainFibronectin type-III 15
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231975_219017101747.0DomainFibrinogen C-terminal
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201533_162115281565.0DomainFibronectin type-III 11
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201622_171115281565.0DomainFibronectin type-III 12
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201712_180115281565.0DomainFibronectin type-III 13
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201802_188815281565.0DomainFibronectin type-III 14
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201889_197715281565.0DomainFibronectin type-III 15
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201975_219015281565.0DomainFibrinogen C-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGAPDHchr12:6646176chr9:117783546ENST00000229239+59245_250109336.0Motif[IL]-x-C-x-x-[DE] motif
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396858+48245_25067294.0Motif[IL]-x-C-x-x-[DE] motif
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396859+48245_250109336.0Motif[IL]-x-C-x-x-[DE] motif
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396861+59245_250109336.0Motif[IL]-x-C-x-x-[DE] motif
HgeneGAPDHchr12:6646176chr9:117783546ENST00000229239+59151_153109336.0RegionGlyceraldehyde 3-phosphate binding
HgeneGAPDHchr12:6646176chr9:117783546ENST00000229239+59211_212109336.0RegionGlyceraldehyde 3-phosphate binding
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396858+48151_15367294.0RegionGlyceraldehyde 3-phosphate binding
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396858+48211_21267294.0RegionGlyceraldehyde 3-phosphate binding
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396859+48151_153109336.0RegionGlyceraldehyde 3-phosphate binding
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396859+48211_212109336.0RegionGlyceraldehyde 3-phosphate binding
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396861+59151_153109336.0RegionGlyceraldehyde 3-phosphate binding
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396861+59211_212109336.0RegionGlyceraldehyde 3-phosphate binding
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224118_14518011838.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921118_14515281565.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022118_14516191656.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628118_14521652202.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123118_14517101747.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820118_14515281565.0Coiled coilOntology_term=ECO:0000255
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241076_116518011838.0DomainFibronectin type-III 6
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241167_125618011838.0DomainFibronectin type-III 7
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241258_135018011838.0DomainFibronectin type-III 8
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241351_143918011838.0DomainFibronectin type-III 9
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241440_153118011838.0DomainFibronectin type-III 10
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241533_162118011838.0DomainFibronectin type-III 11
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241622_171118011838.0DomainFibronectin type-III 12
TgeneTNCchr12:6646176chr9:117783546ENST0000034009422241712_180118011838.0DomainFibronectin type-III 13
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224174_18618011838.0DomainEGF-like 1%3B incomplete
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224186_21718011838.0DomainEGF-like 2
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224217_24818011838.0DomainEGF-like 3
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224248_28018011838.0DomainEGF-like 4
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224280_31118011838.0DomainEGF-like 5
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224311_34218011838.0DomainEGF-like 6
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224342_37318011838.0DomainEGF-like 7
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224373_40418011838.0DomainEGF-like 8
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224404_43518011838.0DomainEGF-like 9
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224435_46618011838.0DomainEGF-like 10
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224466_49718011838.0DomainEGF-like 11
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224497_52818011838.0DomainEGF-like 12
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224528_55918011838.0DomainEGF-like 13
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224559_59018011838.0DomainEGF-like 14
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224590_62118011838.0DomainEGF-like 15
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224625_71518011838.0DomainFibronectin type-III 1
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224716_80418011838.0DomainFibronectin type-III 2
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224805_89418011838.0DomainFibronectin type-III 3
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224895_99018011838.0DomainFibronectin type-III 4
TgeneTNCchr12:6646176chr9:117783546ENST000003400942224991_107518011838.0DomainFibronectin type-III 5
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211076_116515281565.0DomainFibronectin type-III 6
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211167_125615281565.0DomainFibronectin type-III 7
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211258_135015281565.0DomainFibronectin type-III 8
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211351_143915281565.0DomainFibronectin type-III 9
TgeneTNCchr12:6646176chr9:117783546ENST0000034523019211440_153115281565.0DomainFibronectin type-III 10
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921174_18615281565.0DomainEGF-like 1%3B incomplete
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921186_21715281565.0DomainEGF-like 2
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921217_24815281565.0DomainEGF-like 3
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921248_28015281565.0DomainEGF-like 4
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921280_31115281565.0DomainEGF-like 5
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921311_34215281565.0DomainEGF-like 6
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921342_37315281565.0DomainEGF-like 7
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921373_40415281565.0DomainEGF-like 8
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921404_43515281565.0DomainEGF-like 9
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921435_46615281565.0DomainEGF-like 10
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921466_49715281565.0DomainEGF-like 11
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921497_52815281565.0DomainEGF-like 12
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921528_55915281565.0DomainEGF-like 13
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921559_59015281565.0DomainEGF-like 14
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921590_62115281565.0DomainEGF-like 15
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921625_71515281565.0DomainFibronectin type-III 1
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921716_80415281565.0DomainFibronectin type-III 2
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921805_89415281565.0DomainFibronectin type-III 3
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921895_99015281565.0DomainFibronectin type-III 4
TgeneTNCchr12:6646176chr9:117783546ENST000003452301921991_107515281565.0DomainFibronectin type-III 5
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221076_116516191656.0DomainFibronectin type-III 6
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221167_125616191656.0DomainFibronectin type-III 7
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221258_135016191656.0DomainFibronectin type-III 8
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221351_143916191656.0DomainFibronectin type-III 9
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221440_153116191656.0DomainFibronectin type-III 10
TgeneTNCchr12:6646176chr9:117783546ENST0000034670620221533_162116191656.0DomainFibronectin type-III 11
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022174_18616191656.0DomainEGF-like 1%3B incomplete
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022186_21716191656.0DomainEGF-like 2
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022217_24816191656.0DomainEGF-like 3
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022248_28016191656.0DomainEGF-like 4
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022280_31116191656.0DomainEGF-like 5
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022311_34216191656.0DomainEGF-like 6
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022342_37316191656.0DomainEGF-like 7
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022373_40416191656.0DomainEGF-like 8
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022404_43516191656.0DomainEGF-like 9
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022435_46616191656.0DomainEGF-like 10
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022466_49716191656.0DomainEGF-like 11
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022497_52816191656.0DomainEGF-like 12
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022528_55916191656.0DomainEGF-like 13
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022559_59016191656.0DomainEGF-like 14
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022590_62116191656.0DomainEGF-like 15
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022625_71516191656.0DomainFibronectin type-III 1
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022716_80416191656.0DomainFibronectin type-III 2
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022805_89416191656.0DomainFibronectin type-III 3
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022895_99016191656.0DomainFibronectin type-III 4
TgeneTNCchr12:6646176chr9:117783546ENST000003467062022991_107516191656.0DomainFibronectin type-III 5
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281076_116521652202.0DomainFibronectin type-III 6
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281167_125621652202.0DomainFibronectin type-III 7
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281258_135021652202.0DomainFibronectin type-III 8
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281351_143921652202.0DomainFibronectin type-III 9
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281440_153121652202.0DomainFibronectin type-III 10
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281533_162121652202.0DomainFibronectin type-III 11
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281622_171121652202.0DomainFibronectin type-III 12
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281712_180121652202.0DomainFibronectin type-III 13
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628174_18621652202.0DomainEGF-like 1%3B incomplete
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281802_188821652202.0DomainFibronectin type-III 14
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628186_21721652202.0DomainEGF-like 2
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281889_197721652202.0DomainFibronectin type-III 15
TgeneTNCchr12:6646176chr9:117783546ENST0000035076326281975_219021652202.0DomainFibrinogen C-terminal
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628217_24821652202.0DomainEGF-like 3
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628248_28021652202.0DomainEGF-like 4
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628280_31121652202.0DomainEGF-like 5
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628311_34221652202.0DomainEGF-like 6
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628342_37321652202.0DomainEGF-like 7
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628373_40421652202.0DomainEGF-like 8
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628404_43521652202.0DomainEGF-like 9
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628435_46621652202.0DomainEGF-like 10
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628466_49721652202.0DomainEGF-like 11
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628497_52821652202.0DomainEGF-like 12
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628528_55921652202.0DomainEGF-like 13
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628559_59021652202.0DomainEGF-like 14
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628590_62121652202.0DomainEGF-like 15
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628625_71521652202.0DomainFibronectin type-III 1
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628716_80421652202.0DomainFibronectin type-III 2
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628805_89421652202.0DomainFibronectin type-III 3
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628895_99021652202.0DomainFibronectin type-III 4
TgeneTNCchr12:6646176chr9:117783546ENST000003507632628991_107521652202.0DomainFibronectin type-III 5
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231076_116517101747.0DomainFibronectin type-III 6
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231167_125617101747.0DomainFibronectin type-III 7
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231258_135017101747.0DomainFibronectin type-III 8
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231351_143917101747.0DomainFibronectin type-III 9
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231440_153117101747.0DomainFibronectin type-III 10
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231533_162117101747.0DomainFibronectin type-III 11
TgeneTNCchr12:6646176chr9:117783546ENST0000053564821231622_171117101747.0DomainFibronectin type-III 12
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123174_18617101747.0DomainEGF-like 1%3B incomplete
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123186_21717101747.0DomainEGF-like 2
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123217_24817101747.0DomainEGF-like 3
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123248_28017101747.0DomainEGF-like 4
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123280_31117101747.0DomainEGF-like 5
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123311_34217101747.0DomainEGF-like 6
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123342_37317101747.0DomainEGF-like 7
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123373_40417101747.0DomainEGF-like 8
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123404_43517101747.0DomainEGF-like 9
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123435_46617101747.0DomainEGF-like 10
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123466_49717101747.0DomainEGF-like 11
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123497_52817101747.0DomainEGF-like 12
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123528_55917101747.0DomainEGF-like 13
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123559_59017101747.0DomainEGF-like 14
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123590_62117101747.0DomainEGF-like 15
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123625_71517101747.0DomainFibronectin type-III 1
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123716_80417101747.0DomainFibronectin type-III 2
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123805_89417101747.0DomainFibronectin type-III 3
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123895_99017101747.0DomainFibronectin type-III 4
TgeneTNCchr12:6646176chr9:117783546ENST000005356482123991_107517101747.0DomainFibronectin type-III 5
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201076_116515281565.0DomainFibronectin type-III 6
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201167_125615281565.0DomainFibronectin type-III 7
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201258_135015281565.0DomainFibronectin type-III 8
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201351_143915281565.0DomainFibronectin type-III 9
TgeneTNCchr12:6646176chr9:117783546ENST0000053732018201440_153115281565.0DomainFibronectin type-III 10
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820174_18615281565.0DomainEGF-like 1%3B incomplete
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820186_21715281565.0DomainEGF-like 2
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820217_24815281565.0DomainEGF-like 3
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820248_28015281565.0DomainEGF-like 4
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820280_31115281565.0DomainEGF-like 5
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820311_34215281565.0DomainEGF-like 6
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820342_37315281565.0DomainEGF-like 7
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820373_40415281565.0DomainEGF-like 8
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820404_43515281565.0DomainEGF-like 9
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820435_46615281565.0DomainEGF-like 10
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820466_49715281565.0DomainEGF-like 11
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820497_52815281565.0DomainEGF-like 12
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820528_55915281565.0DomainEGF-like 13
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820559_59015281565.0DomainEGF-like 14
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820590_62115281565.0DomainEGF-like 15
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820625_71515281565.0DomainFibronectin type-III 1
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820716_80415281565.0DomainFibronectin type-III 2
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820805_89415281565.0DomainFibronectin type-III 3
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820895_99015281565.0DomainFibronectin type-III 4
TgeneTNCchr12:6646176chr9:117783546ENST000005373201820991_107515281565.0DomainFibronectin type-III 5


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Fusion Gene Sequence for GAPDH-TNC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>32420_32420_1_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000229239_TNC_chr9_117783546_ENST00000350763_length(transcript)=1727nt_BP=993nt
GGGGGAAGTGGGGGCTGGGAAGGAACCACGGGCCCCCGCCCGAGGCCCATGGGCCCCTCCTAGGCCTTTGCCTGAGCAGTCCGGTGTCAC
TACCGCAGAGCCTCGAGGAGAAGTTCCCCAACTTTCCCGCCTCTCAGCCTTTGAAAGAAAGAAAGGGGAGGGGGCAGGCCGCGTGCAGCC
GCGAGCGGTGCTGGGCTCCGGCTCCAATTCCCCATCTCAGTCGTTCCCAAAGTCCTCCTGTTTCATCCAAGCGTGTAAGGGTCCCCGTCC
TTGACTCCCTAGTGTCCTGCTGCCCACAGTCCAGTCCTGGGAACCAGCACCGATCACCTCCCATCGGGCCAATCTCAGTCCCTTCCCCCC
TACGTCGGGGCCCACACGCTCGGTGCGTGCCCAGTTGAACCAGGCGGCTGCGGAAAAAAAAAAGCGGGGAGAAAGTAGGGCCCGGCTACT
AGCGGTTTTACGGGCGCACGTAGCTCAGGCCTCAAGACCTTGGGCTGGGACTGGCTGAGCCTGGCGGGAGGCGGGGTCCGAGTCACCGCC
TGCCGCCGCGCCCCCGGTTTCTATAAATTGAGCCCGCAGCCTCCCGCTTCGCTCTCTGCTCCTCCTGTTCGACAGTCAGCCGCATCTTCT
TTTGCGTCGCCAGCCGAGCCACATCGCTCAGACACCATGGGGAAGGTGAAGGTCGGAGTCAACGGATTTGGTCGTATTGGGCGCCTGGTC
ACCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTGACCTCAACTACATGGTTTACATGTTCCAA
TATGATTCCACCCATGGCAAATTCCATGGCACCGTCAAGGCTGAGAACGGGAAGCTTGTCATCAATGGAAATCCCATCACCATCTTCCAG
GAGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTACGTCGTGGAGTCCACTGGCGTCTTCACCACCATGGAGAAGGCT
GGGGGCGTTAACTGGTTCCACTGGAAGGGCCACGAACACTCAATCCAGTTTGCTGAGATGAAGCTGAGACCAAGCAACTTCAGAAATCTT
GAAGGCAGGCGCAAACGGGCATAAATTCCAGGGACCACTGGGTGAGAGAGGAATAAGGCCCAGAGCGAGGAAAGGATTTTACCAAAGCAT
CAATACAACCAGCCCAACCATCGGTCCACACCTGGGCATTTGGTGAGAGTCAAAGCTGACCATGGATCCCTGGGGCCAACGGCAACAGCA
TGGGCCTCACCTCCTCTGTGATTTCTTTCTTTGCACCAAAGACATCAGTCTCCAACATGTTTCTGTTTTGTTGTTTGATTCAGCAAAAAT
CTCCCAGTGACAACATCGCAATAGTTTTTTACTTCTCTTAGGTGGCTCTGGGAATGGGAGAGGGGTAGGATGTACAGGGGTAGTTTGTTT
TAGAACCAGCCGTATTTTACATGAAGCTGTATAATTAATTGTCATTATTTTTGTTAGCAAAGATTAAATGTGTCATTGGAAGCCATCCCT
TTTTTTACATTTCATACAACAGAAACCAGAAAAGCAATACTGTTTCCATTTTAAGGATATGATTAATATTATTAATATAATAATGATGAT
GATGATGATGAAAACTAAGGATTTTTCAAGAGATCTTTCTTTCCAAAACATTTCTGGACAGTACCTGATTGTATTTTTTTTTTAAATAAA

>32420_32420_1_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000229239_TNC_chr9_117783546_ENST00000350763_length(amino acids)=204AA_BP=168
MGWDWLSLAGGGVRVTACRRAPGFYKLSPQPPASLSAPPVRQSAASSFASPAEPHRSDTMGKVKVGVNGFGRIGRLVTRAAFNSGKVDIV
AINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGGVNWFHWKGHEH

--------------------------------------------------------------
>32420_32420_2_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396856_TNC_chr9_117783546_ENST00000350763_length(transcript)=1149nt_BP=415nt
TGTTCGACAGTCAGCCGCATCTTCTTTTGCGTCGCCAGCCGAGCCACATCGCTCAGACACCATGGGGAAGGTGAAGGTCGGAGTCAACGG
ATTTGGTCGTATTGGGCGCCTGGTCACCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTGACCT
CAACTACATGGTTTACATGTTCCAATATGATTCCACCCATGGCAAATTCCATGGCACCGTCAAGGCTGAGAACGGGAAGCTTGTCATCAA
TGGAAATCCCATCACCATCTTCCAGGAGTGAGTGGAAGACAGAATGGAAGAAATGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGG
CGCTGAGTACGTCGTGGAGTCCACTGGCGTCTTCACCACCATGGAGAAGGCTGGGGGCGTTAACTGGTTCCACTGGAAGGGCCACGAACA
CTCAATCCAGTTTGCTGAGATGAAGCTGAGACCAAGCAACTTCAGAAATCTTGAAGGCAGGCGCAAACGGGCATAAATTCCAGGGACCAC
TGGGTGAGAGAGGAATAAGGCCCAGAGCGAGGAAAGGATTTTACCAAAGCATCAATACAACCAGCCCAACCATCGGTCCACACCTGGGCA
TTTGGTGAGAGTCAAAGCTGACCATGGATCCCTGGGGCCAACGGCAACAGCATGGGCCTCACCTCCTCTGTGATTTCTTTCTTTGCACCA
AAGACATCAGTCTCCAACATGTTTCTGTTTTGTTGTTTGATTCAGCAAAAATCTCCCAGTGACAACATCGCAATAGTTTTTTACTTCTCT
TAGGTGGCTCTGGGAATGGGAGAGGGGTAGGATGTACAGGGGTAGTTTGTTTTAGAACCAGCCGTATTTTACATGAAGCTGTATAATTAA
TTGTCATTATTTTTGTTAGCAAAGATTAAATGTGTCATTGGAAGCCATCCCTTTTTTTACATTTCATACAACAGAAACCAGAAAAGCAAT
ACTGTTTCCATTTTAAGGATATGATTAATATTATTAATATAATAATGATGATGATGATGATGAAAACTAAGGATTTTTCAAGAGATCTTT

>32420_32420_2_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396856_TNC_chr9_117783546_ENST00000350763_length(amino acids)=126AA_BP=108
MVVLGAWSPGLLLTLVKWILLPSMTPSLTSTTWFTCSNMIPPMANSMAPSRLRTGSLSSMEIPSPSSRSEWKTEWKKCEIPPKSSGAMLA

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>32420_32420_3_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396858_TNC_chr9_117783546_ENST00000350763_length(transcript)=1200nt_BP=466nt
TGCAACCGGGAAGGAAATGAATGGGCAGCCGTTAGGAAAGCCTGCCGGTGACTAACCCTGCGCTCCTGCCTCGATGGGTGGAGTCGCGTG
TGGCGGGGAAGTCAGGTGGAGCGAGGCTAGCTGGCCCGATTTCTCCTCCGGGTGATGCTTTTCCTAGATTATTCTCTGATTTGGTCGTAT
TGGGCGCCTGGTCACCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTGACCTCAACTACATGGT
TTACATGTTCCAATATGATTCCACCCATGGCAAATTCCATGGCACCGTCAAGGCTGAGAACGGGAAGCTTGTCATCAATGGAAATCCCAT
CACCATCTTCCAGGAGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTACGTCGTGGAGTCCACTGGCGTCTTCACCAC
CATGGAGAAGGCTGGGGGCGTTAACTGGTTCCACTGGAAGGGCCACGAACACTCAATCCAGTTTGCTGAGATGAAGCTGAGACCAAGCAA
CTTCAGAAATCTTGAAGGCAGGCGCAAACGGGCATAAATTCCAGGGACCACTGGGTGAGAGAGGAATAAGGCCCAGAGCGAGGAAAGGAT
TTTACCAAAGCATCAATACAACCAGCCCAACCATCGGTCCACACCTGGGCATTTGGTGAGAGTCAAAGCTGACCATGGATCCCTGGGGCC
AACGGCAACAGCATGGGCCTCACCTCCTCTGTGATTTCTTTCTTTGCACCAAAGACATCAGTCTCCAACATGTTTCTGTTTTGTTGTTTG
ATTCAGCAAAAATCTCCCAGTGACAACATCGCAATAGTTTTTTACTTCTCTTAGGTGGCTCTGGGAATGGGAGAGGGGTAGGATGTACAG
GGGTAGTTTGTTTTAGAACCAGCCGTATTTTACATGAAGCTGTATAATTAATTGTCATTATTTTTGTTAGCAAAGATTAAATGTGTCATT
GGAAGCCATCCCTTTTTTTACATTTCATACAACAGAAACCAGAAAAGCAATACTGTTTCCATTTTAAGGATATGATTAATATTATTAATA
TAATAATGATGATGATGATGATGAAAACTAAGGATTTTTCAAGAGATCTTTCTTTCCAAAACATTTCTGGACAGTACCTGATTGTATTTT

>32420_32420_3_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396858_TNC_chr9_117783546_ENST00000350763_length(amino acids)=160AA_BP=142
MPVTNPALLPRWVESRVAGKSGGARLAGPISPPGDAFPRLFSDLVVLGAWSPGLLLTLVKWILLPSMTPSLTSTTWFTCSNMIPPMANSM

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>32420_32420_4_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396859_TNC_chr9_117783546_ENST00000350763_length(transcript)=1140nt_BP=406nt
AGGCGTGTGTGTCGGCCGGGGCCACTAGGCGCTCACTGTTCTCTCCCTCCGCGCAGCCGAGCCACATCGCTCAGACACCATGGGGAAGGT
GAAGGTCGGAGTCAACGGATTTGGTCGTATTGGGCGCCTGGTCACCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAA
TGACCCCTTCATTGACCTCAACTACATGGTTTACATGTTCCAATATGATTCCACCCATGGCAAATTCCATGGCACCGTCAAGGCTGAGAA
CGGGAAGCTTGTCATCAATGGAAATCCCATCACCATCTTCCAGGAGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTA
CGTCGTGGAGTCCACTGGCGTCTTCACCACCATGGAGAAGGCTGGGGGCGTTAACTGGTTCCACTGGAAGGGCCACGAACACTCAATCCA
GTTTGCTGAGATGAAGCTGAGACCAAGCAACTTCAGAAATCTTGAAGGCAGGCGCAAACGGGCATAAATTCCAGGGACCACTGGGTGAGA
GAGGAATAAGGCCCAGAGCGAGGAAAGGATTTTACCAAAGCATCAATACAACCAGCCCAACCATCGGTCCACACCTGGGCATTTGGTGAG
AGTCAAAGCTGACCATGGATCCCTGGGGCCAACGGCAACAGCATGGGCCTCACCTCCTCTGTGATTTCTTTCTTTGCACCAAAGACATCA
GTCTCCAACATGTTTCTGTTTTGTTGTTTGATTCAGCAAAAATCTCCCAGTGACAACATCGCAATAGTTTTTTACTTCTCTTAGGTGGCT
CTGGGAATGGGAGAGGGGTAGGATGTACAGGGGTAGTTTGTTTTAGAACCAGCCGTATTTTACATGAAGCTGTATAATTAATTGTCATTA
TTTTTGTTAGCAAAGATTAAATGTGTCATTGGAAGCCATCCCTTTTTTTACATTTCATACAACAGAAACCAGAAAAGCAATACTGTTTCC
ATTTTAAGGATATGATTAATATTATTAATATAATAATGATGATGATGATGATGAAAACTAAGGATTTTTCAAGAGATCTTTCTTTCCAAA

>32420_32420_4_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396859_TNC_chr9_117783546_ENST00000350763_length(amino acids)=145AA_BP=109
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDA

--------------------------------------------------------------
>32420_32420_5_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396861_TNC_chr9_117783546_ENST00000350763_length(transcript)=1212nt_BP=478nt
TTCGACAGTCAGCCGCATCTTCTTTTGCGTCGCCAGGTGAAGACGGGCGGAGAGAAACCCGGGAGGCTAGGGACGGCCTGAAGGCGGCAG
GGGCGGGCGCAGGCCGGATGTGTTCGCGCCGCTGCGGGCCGAGCCACATCGCTCAGACACCATGGGGAAGGTGAAGGTCGGAGTCAACGG
ATTTGGTCGTATTGGGCGCCTGGTCACCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTGACCT
CAACTACATGGTTTACATGTTCCAATATGATTCCACCCATGGCAAATTCCATGGCACCGTCAAGGCTGAGAACGGGAAGCTTGTCATCAA
TGGAAATCCCATCACCATCTTCCAGGAGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTACGTCGTGGAGTCCACTGG
CGTCTTCACCACCATGGAGAAGGCTGGGGGCGTTAACTGGTTCCACTGGAAGGGCCACGAACACTCAATCCAGTTTGCTGAGATGAAGCT
GAGACCAAGCAACTTCAGAAATCTTGAAGGCAGGCGCAAACGGGCATAAATTCCAGGGACCACTGGGTGAGAGAGGAATAAGGCCCAGAG
CGAGGAAAGGATTTTACCAAAGCATCAATACAACCAGCCCAACCATCGGTCCACACCTGGGCATTTGGTGAGAGTCAAAGCTGACCATGG
ATCCCTGGGGCCAACGGCAACAGCATGGGCCTCACCTCCTCTGTGATTTCTTTCTTTGCACCAAAGACATCAGTCTCCAACATGTTTCTG
TTTTGTTGTTTGATTCAGCAAAAATCTCCCAGTGACAACATCGCAATAGTTTTTTACTTCTCTTAGGTGGCTCTGGGAATGGGAGAGGGG
TAGGATGTACAGGGGTAGTTTGTTTTAGAACCAGCCGTATTTTACATGAAGCTGTATAATTAATTGTCATTATTTTTGTTAGCAAAGATT
AAATGTGTCATTGGAAGCCATCCCTTTTTTTACATTTCATACAACAGAAACCAGAAAAGCAATACTGTTTCCATTTTAAGGATATGATTA
ATATTATTAATATAATAATGATGATGATGATGATGAAAACTAAGGATTTTTCAAGAGATCTTTCTTTCCAAAACATTTCTGGACAGTACC

>32420_32420_5_GAPDH-TNC_GAPDH_chr12_6646176_ENST00000396861_TNC_chr9_117783546_ENST00000350763_length(amino acids)=155AA_BP=119
MRAEPHRSDTMGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQER

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GAPDH-TNC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneGAPDHchr12:6646176chr9:117783546ENST00000229239+592_148109.0336.0WARS1
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396858+482_14867.0294.0WARS1
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396859+482_148109.0336.0WARS1
HgeneGAPDHchr12:6646176chr9:117783546ENST00000396861+592_148109.0336.0WARS1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GAPDH-TNC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GAPDH-TNC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource