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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AK4-NDC1 (FusionGDB2 ID:3243)

Fusion Gene Summary for AK4-NDC1

check button Fusion gene summary
Fusion gene informationFusion gene name: AK4-NDC1
Fusion gene ID: 3243
HgeneTgene
Gene symbol

AK4

NDC1

Gene ID

205

55706

Gene nameadenylate kinase 4NDC1 transmembrane nucleoporin
SynonymsAK 4|AK3|AK3L1|AK3L2NET3|TMEM48
Cytomap

1p31.3

1p32.3

Type of geneprotein-codingprotein-coding
Descriptionadenylate kinase 4, mitochondrialATP-AMP transphosphorylaseGTP:AMP phosphotransferase AK4, mitochondrialadenylate kinase 3-like 1adenylate kinase isoenzyme 4, mitochondrialepididymis secretory sperm binding proteinmitochondrial adenylate kinase-3nunucleoporin NDC1nuclear division cycle 1 homologtransmembrane protein 48
Modification date2020031520200313
UniProtAcc

P27144

Q9BTX1

Ensembl transtripts involved in fusion geneENST00000470888, ENST00000327299, 
ENST00000395334, ENST00000545314, 
ENST00000546702, 		ENST00000371429, 
ENST00000540001, ENST00000234725, 
ENST00000480952, ENST00000537333, 
Fusion gene scores* DoF score2 X 2 X 2=88 X 6 X 7=336
# samples 39
** MAII scorelog2(3/8*10)=1.90689059560852log2(9/336*10)=-1.90046432644909
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AK4 [Title/Abstract] AND NDC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAK4(65656512)-NDC1(54293846), # samples:2
Anticipated loss of major functional domain due to fusion event.AK4-NDC1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
AK4-NDC1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAK4

GO:0006165

nucleoside diphosphate phosphorylation

23416111

HgeneAK4

GO:0009142

nucleoside triphosphate biosynthetic process

23416111

HgeneAK4

GO:0046033

AMP metabolic process

19766732

HgeneAK4

GO:0046034

ATP metabolic process

19766732

HgeneAK4

GO:0046039

GTP metabolic process

19766732


check buttonFusion gene breakpoints across AK4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NDC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A8NE-01AAK4chr1

65656512

+NDC1chr1

54293846

-
ChimerDB4ESCATCGA-L5-A8NEAK4chr1

65656512

+NDC1chr1

54291609

-
ChimerDB4ESCATCGA-L5-A8NEAK4chr1

65656512

+NDC1chr1

54293846

-


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Fusion Gene ORF analysis for AK4-NDC1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000470888ENST00000371429AK4chr1

65656512

+NDC1chr1

54293846

-
3UTR-3CDSENST00000470888ENST00000371429AK4chr1

65656512

+NDC1chr1

54291609

-
3UTR-3CDSENST00000470888ENST00000540001AK4chr1

65656512

+NDC1chr1

54293846

-
3UTR-3CDSENST00000470888ENST00000540001AK4chr1

65656512

+NDC1chr1

54291609

-
3UTR-5UTRENST00000470888ENST00000234725AK4chr1

65656512

+NDC1chr1

54293846

-
3UTR-5UTRENST00000470888ENST00000234725AK4chr1

65656512

+NDC1chr1

54291609

-
3UTR-5UTRENST00000470888ENST00000480952AK4chr1

65656512

+NDC1chr1

54293846

-
3UTR-5UTRENST00000470888ENST00000480952AK4chr1

65656512

+NDC1chr1

54291609

-
3UTR-5UTRENST00000470888ENST00000537333AK4chr1

65656512

+NDC1chr1

54293846

-
3UTR-5UTRENST00000470888ENST00000537333AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000327299ENST00000234725AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000327299ENST00000234725AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000327299ENST00000480952AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000327299ENST00000480952AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000327299ENST00000537333AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000327299ENST00000537333AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000395334ENST00000234725AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000395334ENST00000234725AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000395334ENST00000480952AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000395334ENST00000480952AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000395334ENST00000537333AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000395334ENST00000537333AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000545314ENST00000234725AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000545314ENST00000234725AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000545314ENST00000480952AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000545314ENST00000480952AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000545314ENST00000537333AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000545314ENST00000537333AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000546702ENST00000234725AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000546702ENST00000234725AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000546702ENST00000480952AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000546702ENST00000480952AK4chr1

65656512

+NDC1chr1

54291609

-
5CDS-5UTRENST00000546702ENST00000537333AK4chr1

65656512

+NDC1chr1

54293846

-
5CDS-5UTRENST00000546702ENST00000537333AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000327299ENST00000371429AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000327299ENST00000540001AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000395334ENST00000371429AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000395334ENST00000540001AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000545314ENST00000371429AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000545314ENST00000540001AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000546702ENST00000371429AK4chr1

65656512

+NDC1chr1

54291609

-
Frame-shiftENST00000546702ENST00000540001AK4chr1

65656512

+NDC1chr1

54291609

-
In-frameENST00000327299ENST00000371429AK4chr1

65656512

+NDC1chr1

54293846

-
In-frameENST00000327299ENST00000540001AK4chr1

65656512

+NDC1chr1

54293846

-
In-frameENST00000395334ENST00000371429AK4chr1

65656512

+NDC1chr1

54293846

-
In-frameENST00000395334ENST00000540001AK4chr1

65656512

+NDC1chr1

54293846

-
In-frameENST00000545314ENST00000371429AK4chr1

65656512

+NDC1chr1

54293846

-
In-frameENST00000545314ENST00000540001AK4chr1

65656512

+NDC1chr1

54293846

-
In-frameENST00000546702ENST00000371429AK4chr1

65656512

+NDC1chr1

54293846

-
In-frameENST00000546702ENST00000540001AK4chr1

65656512

+NDC1chr1

54293846

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000545314AK4chr165656512+ENST00000371429NDC1chr154293846-47675122202256678
ENST00000545314AK4chr165656512+ENST00000540001NDC1chr154293846-46545122201860546
ENST00000546702AK4chr165656512+ENST00000371429NDC1chr154293846-4469214121958648
ENST00000546702AK4chr165656512+ENST00000540001NDC1chr154293846-4356214121562516
ENST00000395334AK4chr165656512+ENST00000371429NDC1chr154293846-48786233312367678
ENST00000395334AK4chr165656512+ENST00000540001NDC1chr154293846-47656233311971546
ENST00000327299AK4chr165656512+ENST00000371429NDC1chr154293846-472547072214735
ENST00000327299AK4chr165656512+ENST00000540001NDC1chr154293846-461247071818603

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000545314ENST00000371429AK4chr165656512+NDC1chr154293846-0.0012251240.9987748
ENST00000545314ENST00000540001AK4chr165656512+NDC1chr154293846-0.003895430.9961046
ENST00000546702ENST00000371429AK4chr165656512+NDC1chr154293846-0.0027000810.99729997
ENST00000546702ENST00000540001AK4chr165656512+NDC1chr154293846-0.0067090690.9932909
ENST00000395334ENST00000371429AK4chr165656512+NDC1chr154293846-0.0012645980.99873537
ENST00000395334ENST00000540001AK4chr165656512+NDC1chr154293846-0.0040640280.9959359
ENST00000327299ENST00000371429AK4chr165656512+NDC1chr154293846-0.001137710.99886227
ENST00000327299ENST00000540001AK4chr165656512+NDC1chr154293846-0.0036316070.9963684

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Fusion Genomic Features for AK4-NDC1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for AK4-NDC1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:65656512/chr1:54293846)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AK4

P27144

NDC1

Q9BTX1

FUNCTION: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates (PubMed:19073142, PubMed:19766732, PubMed:23416111, PubMed:24767988). Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor (PubMed:19073142, PubMed:19766732, PubMed:23416111). Also displays broad nucleoside diphosphate kinase activity (PubMed:19073142, PubMed:19766732, PubMed:23416111). Plays a role in controlling cellular ATP levels by regulating phosphorylation and activation of the energy sensor protein kinase AMPK (PubMed:24767988, PubMed:26980435). Plays a protective role in the cellular response to oxidative stress (PubMed:19130895, PubMed:23474458, PubMed:26980435). {ECO:0000255|HAMAP-Rule:MF_03170, ECO:0000269|PubMed:19073142, ECO:0000269|PubMed:19130895, ECO:0000269|PubMed:19766732, ECO:0000269|PubMed:23416111, ECO:0000269|PubMed:23474458, ECO:0000269|PubMed:24767988, ECO:0000269|PubMed:26980435}.FUNCTION: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane. {ECO:0000269|PubMed:16600873, ECO:0000269|PubMed:16702233}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAK4chr1:65656512chr1:54293846ENST00000327299+2515_2088224.0Nucleotide bindingNTP
HgeneAK4chr1:65656512chr1:54293846ENST00000327299+2562_6488224.0Nucleotide bindingAMP
HgeneAK4chr1:65656512chr1:54293846ENST00000395334+3615_2088224.0Nucleotide bindingNTP
HgeneAK4chr1:65656512chr1:54293846ENST00000395334+3662_6488224.0Nucleotide bindingAMP
HgeneAK4chr1:65656512chr1:54293846ENST00000545314+3615_2088224.0Nucleotide bindingNTP
HgeneAK4chr1:65656512chr1:54293846ENST00000545314+3662_6488224.0Nucleotide bindingAMP
HgeneAK4chr1:65656512chr1:54293846ENST00000327299+2535_6488224.0RegionNMP
HgeneAK4chr1:65656512chr1:54293846ENST00000395334+3635_6488224.0RegionNMP
HgeneAK4chr1:65656512chr1:54293846ENST00000545314+3635_6488224.0RegionNMP
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218136_16593675.0Topological domainPerinuclear space
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218187_22593675.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218247_27293675.0Topological domainPerinuclear space
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218294_67493675.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217136_165931297.0Topological domainPerinuclear space
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217187_225931297.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217247_272931297.0Topological domainPerinuclear space
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217294_674931297.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218115_13593675.0TransmembraneHelical%3B Name%3D3
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218166_18693675.0TransmembraneHelical%3B Name%3D4
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218226_24693675.0TransmembraneHelical%3B Name%3D5
TgeneNDC1chr1:65656512chr1:54293846ENST00000371429218273_29393675.0TransmembraneHelical%3B Name%3D6
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217115_135931297.0TransmembraneHelical%3B Name%3D3
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217166_186931297.0TransmembraneHelical%3B Name%3D4
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217226_246931297.0TransmembraneHelical%3B Name%3D5
TgeneNDC1chr1:65656512chr1:54293846ENST00000540001217273_293931297.0TransmembraneHelical%3B Name%3D6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAK4chr1:65656512chr1:54293846ENST00000327299+25135_13688224.0Nucleotide bindingNTP
HgeneAK4chr1:65656512chr1:54293846ENST00000327299+2589_9288224.0Nucleotide bindingAMP
HgeneAK4chr1:65656512chr1:54293846ENST00000395334+36135_13688224.0Nucleotide bindingNTP
HgeneAK4chr1:65656512chr1:54293846ENST00000395334+3689_9288224.0Nucleotide bindingAMP
HgeneAK4chr1:65656512chr1:54293846ENST00000545314+36135_13688224.0Nucleotide bindingNTP
HgeneAK4chr1:65656512chr1:54293846ENST00000545314+3689_9288224.0Nucleotide bindingAMP
HgeneAK4chr1:65656512chr1:54293846ENST00000327299+25125_16288224.0RegionLID
HgeneAK4chr1:65656512chr1:54293846ENST00000395334+36125_16288224.0RegionLID
HgeneAK4chr1:65656512chr1:54293846ENST00000545314+36125_16288224.0RegionLID
TgeneNDC1chr1:65656512chr1:54293846ENST000003714292181_2493675.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST0000037142921846_6893675.0Topological domainPerinuclear space
TgeneNDC1chr1:65656512chr1:54293846ENST0000037142921890_11493675.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST000005400012171_24931297.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST0000054000121746_68931297.0Topological domainPerinuclear space
TgeneNDC1chr1:65656512chr1:54293846ENST0000054000121790_114931297.0Topological domainCytoplasmic
TgeneNDC1chr1:65656512chr1:54293846ENST0000037142921825_4593675.0TransmembraneHelical%3B Name%3D1
TgeneNDC1chr1:65656512chr1:54293846ENST0000037142921869_8993675.0TransmembraneHelical%3B Name%3D2
TgeneNDC1chr1:65656512chr1:54293846ENST0000054000121725_45931297.0TransmembraneHelical%3B Name%3D1
TgeneNDC1chr1:65656512chr1:54293846ENST0000054000121769_89931297.0TransmembraneHelical%3B Name%3D2


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Fusion Gene Sequence for AK4-NDC1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>3243_3243_1_AK4-NDC1_AK4_chr1_65656512_ENST00000327299_NDC1_chr1_54293846_ENST00000371429_length(transcript)=4725nt_BP=470nt
AGTCCGCCTGCTACTCGGTCCCGGCGCTGGGCTGAGGGGAGGGGTTGTCTTAAAAGTCTCTCCTTCCCCCTGTAGGGGCGGCCGGCGAGT
CCCAGTGAGAGCGGAGGGTGCCAGAGGTAGGGGGCCGAGAAACAAAGTTCCCGGGGCTTCCTCCGGGGCCGCGGTCGGGGCTGCGCGTTT
GACCGCCCCCCTCCTCGCGAAGGCAATGGCTTCCAAACTCCTGCGCGCGGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACCGTGTG
CCAGAGGATCGCCCAGAACTTTGGTCTCCAGCATCTCTCCAGCGGCCACTTCTTGCGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGA
GATGGCAAAGCAGTATATAGAGAAAAGTCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTGGAGAACAGGCGTGG
CCAGCACTGGCTCCTTGATGTTGTGCCTTCTATTCCTTGCTCCAGACTAGCTCTGATAGGGAAGATCATTCATCCTCAGCAACTCATGCA
CTCATTTATTCATGCTGCAATGGGAATGGTGATGGCCTGGTGTGCTGCAGTGATAACCCAGGGCCAGTACAGCTTTCTTGTGGTTCCCTG
CACTGGTACTAACAGCTTTGGTAGCCCTGCTGCGCAAACCTGCTTAAATGAATATCATCTTTTTTTCCTACTGACTGGAGCATTTATGGG
CTATAGCTATAGCCTCCTGTATTTTGTTAACAACATGAACTATCTTCCATTTCCCATCATACAGCAATACAAGTTCTTGCGTTTTAGGAG
ATCTCTGCTCTTATTAGTTAAACACAGTTGTGTGGAATCACTGTTCCTGGTTAGAAATTTCTGCATTTTATATTATTTTCTTGGCTATAT
TCCCAAAGCTTGGATTAGCACTGCTATGAACCTTCACATAGATGAGCAGGTTCATAGGCCACTTGACACAGTGAGTGGCCTCTTAAATCT
CTCGTTACTCTACCATGTCTGGCTGTGTGGTGTCTTTCTCCTGACGACTTGGTATGTCTCATGGATACTCTTCAAAATCTATGCCACAGA
GGCTCATGTGTTTCCTGTTCAACCACCATTTGCAGAAGGGTCAGATGAGTGCCTTCCAAAAGTGTTAAATAGCAATCCTCCCCCCATCAT
AAAGTATTTAGCCTTGCAGGACCTGATGTTGCTTTCTCAATATTCTCCTTCACGAAGACAAGAAGTTTTCAGCCTCAGCCAACCAGGTGG
ACATCCCCACAATTGGACAGCCATTTCAAGGGAGTGTTTGAATCTTTTAAATGGTATGACTCAGAAACTGATTCTCTATCAAGAAGCTGC
TGCTACGAATGGGAGAGTGTCTTCATCTTACCCAGTGGAACCTAAGAAATTAAATTCTCCAGAAGAAACTGCTTTTCAGACACCAAAATC
TAGCCAGATGCCTCGGCCTTCAGTGCCACCATTAGTTAAAACATCACTGTTTTCTTCAAAATTATCTACACCTGATGTTGTGAGCCCATT
TGGGACCCCATTTGGCTCTAGTGTAATGAATCGGATGGCTGGAATTTTTGATGTAAACACCTGCTATGGGTCACCGCAAAGTCCTCAGCT
AATAAGAAGGGGGCCAAGATTGTGGACATCAGCTTCTGATCAGCAAATGACTGAATTTTCTAATCCTTCTCCATCTACCTCTATTAGTGC
TGAGGGTAAGACAATGAGACAACCCAGTGTGATTTATTCATGGATTCAGAATAAACGTGAACAGATTAAGAATTTCTTGTCAAAACGGGT
GCTGATAATGTATTTTTTCAGTAAGCACCCAGAGGCCTCCATTCAGGCTGTTTTTTCAGATGCCCAAATGCATATTTGGGCATTAGAAGG
TCTGTCGCACTTAGTAGCAGCATCATTTACAGAGGATAGATTTGGAGTTGTCCAGACGACACTACCAGCTATCCTTAATACTTTGTTGAC
ACTGCAAGAGGCAGTCGACAAGTACTTTAAGCTTCCTCATGCTTCCAGTAAACCACCCCGGATTTCAGGAAGCCTTGTGGACACTTCATA
TAAAACATTAAGATTTGCATTCAGAGCATCACTGAAAACTGCCATCTATCGAATAACTACTACATTTGGTGAACATCTGAATGCTGTGCA
AGCATCTGCAGAACATCAGAAAAGACTTCAACAGTTCTTGGAGTTCAAAGAATAGTTAAGTAATATAAACTGTGTTCATTACACTGCTGA
TACAACTACAGATGGGACAGTAAATGTTCAGCATTCTTGGATCAGAAGAAAACGGACTAATTAGATGCTTCCTTTGTCGTGGTGGTTGCT
TTGAAAACTATACTTTAATGGGAGAAATCATGGAAAGAAATTCTCAACAGAATAACTGAAAACTGCCTTTTCTGTACCGATTGCTTTTTG
TGTGTGTGGTATAATAAAATCTTTATTCAATTTTACAGAAGCATTGATGGCAGTCGAAATGTCTCTAGCTCATATAACTTAATAGTAATA
ACTAAAAAACTTTTAGAATTTACTTTTGAAAGGAGGGAAGCCAGTTCTGAAATGAGTATAGGTTGATTTCATAGTCTTCTTAATTAAGAG
TTTAGCTCTTTGTAAACTCAAAATACATAAACTTTTTAAGTGTAGTTTCATTTACTGAAGGATAAAAATGGTAACAGTGCAGCAATATTC
ACAAAAAATATTGTCTAACGGACATATTTTGTTAATCTGTTAGGTTGGGTTTTTGTTTCCAGGGACAAATTAAATTTGTATGATTACCCA
AAAAAGGGTCTCAGTTTACAGATGCTAACTCTATATAAAGGAATGTGGAAAAACTCAGTTCTTAAGTTACAAGATTAAAAATTCACATTT
GGTCTTTAAGAAACAATTGACTGACATCTATGAATTTATTTTGTATCATGCTAGTAAACACGAAGTATTAATGTATGGGTATTTTCCCAG
CTAGTTTTGCTTTCTTTTTCTGGAGCAAAACATTAAGTGATTGCAGAGTTTTTCAAGCAAGAGAAAAAGGTTTGCAAAAAAACCCAGGAA
ATGTTCCCTTTTTTCCCCACCATTCATCTTCATTAGATCAAATTCTGTGAAACTTGTCTGGTCTCTCAAAGGGAGCAGCCTCTGTAGTGT
TAAATGGCTAATTAAAATAGGAAGATCTTTATAGCCAGAAACAACTTAGTCATCAAATAGCAAGTGAAACCAAAACGTCAGAGGGATTAC
TGTACTTGGAAGTATGTTGTGTGTCCCAAATGTGAACGAAGTATTGTTAGAATTTATTAGATCAGCTTCTTTGGAGATCAAAGATTGGAA
ATCCTAGTCATAGATATTCACTGGACTGGCTTTGGACTGAAATGCTCCTTTGTAATTCTTTTCCTATTGTCTTTTCCTTCTAGTGTCCCA
AAATATTTTCTTTAAAGTCAGCACAGTACTGTATATGAATCTTTAATGTGGTATCATATATGTCTACTTTTGTCTGATTCATCGATGTAT
TATATCTTTATAATTGAATATTTTAGCTCCGGGTCCTGTTGCCCCTTCAAGCAGTACATGCCAAATTATAAATAGGTGCTACTGGCCTTG
AGCATATCACTGTGGGACAGTTCCCCAATTGTCAAGTGTTTAGATATGTAGACTATTGCCATTTGTTTTTTTGTTTTGGTTTTGCTTTGT
GTCTGAAGCTGAATTGATTTCTTTTTTTTGAATGTGAAAGTTGAATTTCAAACGTAGTCATTTCTTACAGATGGCCAAGACAGAAAATTG
TGGCTAGGTTGACTGAGAACTGTTGTCTTCCATGTATTAACACAATTAAGCTTTTTATATTCCACTCTCTGTGCTGACCCTGGCTGAGGC
ATTTTGGGAGACAAGGACTCTGAATCTTCTGCTTCCATTAAAGAAGAACTGTGATATTCAACATTGGATTTCTGAGAATAAAGATAGGAT
GATTCCTTTGAACTTTGACTTACTTGTATAAAATGTCCAGCTAGGTTAGGTTTTTGCCATTTCCTATATACTTTGGGTAAAGCTACATTT
GATGAGCAATGTGAATGTTTCTGAGAATGTTCATTCCTGTTTTCTCTTAAGAGAATGTGCTGTGTACTAAATACAGGCCACATAGTGTCT
GCCTGTTGAAGATCTGGAAACTGCCTCCCCAGATCTGTATTGTATTTGGTAGGTAAGGGGGTCAGTTTCTTTTTCTCATTGTGTGTTGAT
AATCTACACACCATCTGTTGGAACCAGGGTGTTATTATGGGGAACTCCTCCTGTGTACTAGGAGGAGGACCTTAGGGAGACCAAGAGGAG
AGAAGCATTTCCTTTGATGAAGTCACATCCTGTCTATGAGCCCACTAATGCTGTAACATTGGCCTGAAAGAGAGTGTTCTTTAAAAGCCT
TTCTCGGCTGTTAGTATAAAAACATGATGGTATCAGCTCTTAGCATGTTTGCTTGACCCTTATGGAAGGTATAAATCCACAGAACTTCCT
TCCCAGAGAACTGGGAAATTGTCCTAGAAATAAACCTTGTACAGTTGAGTGGACATGGATAAGCAACAATTTGTTACTTTGCAGGATTTG
TTCCTTGGTAATTGTTTGGTGTGTCATCCTGTAAATATTCATGATAGTCTGTTTATATCCTTTTGTATATCGTTGATACTGGATTGGGTA

>3243_3243_1_AK4-NDC1_AK4_chr1_65656512_ENST00000327299_NDC1_chr1_54293846_ENST00000371429_length(amino acids)=735AA_BP=154
MLLGPGAGLRGGVVLKVSPSPCRGGRRVPVRAEGARGRGPRNKVPGASSGAAVGAARLTAPLLAKAMASKLLRAVILGPPGSGKGTVCQR
IAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRRGQHWLLDVVPSIPCSRLALIGKIIHPQQLMHSF
IHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSL
LLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAH
VFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLNLLNGMTQKLILYQEAAAT
NGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIR
RGPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIMYFFSKHPEASIQAVFSDAQMHIWALEGLS
HLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQAS

--------------------------------------------------------------
>3243_3243_2_AK4-NDC1_AK4_chr1_65656512_ENST00000327299_NDC1_chr1_54293846_ENST00000540001_length(transcript)=4612nt_BP=470nt
AGTCCGCCTGCTACTCGGTCCCGGCGCTGGGCTGAGGGGAGGGGTTGTCTTAAAAGTCTCTCCTTCCCCCTGTAGGGGCGGCCGGCGAGT
CCCAGTGAGAGCGGAGGGTGCCAGAGGTAGGGGGCCGAGAAACAAAGTTCCCGGGGCTTCCTCCGGGGCCGCGGTCGGGGCTGCGCGTTT
GACCGCCCCCCTCCTCGCGAAGGCAATGGCTTCCAAACTCCTGCGCGCGGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACCGTGTG
CCAGAGGATCGCCCAGAACTTTGGTCTCCAGCATCTCTCCAGCGGCCACTTCTTGCGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGA
GATGGCAAAGCAGTATATAGAGAAAAGTCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTGGAGAACAGGCGTGG
CCAGCACTGGCTCCTTGATGTTGTGCCTTCTATTCCTTGCTCCAGACTAGCTCTGATAGGGAAGATCATTCATCCTCAGCAACTCATGCA
CTCATTTATTCATGCTGCAATGGGAATGGTGATGGCCTGGTGTGCTGCAGTGATAACCCAGGGCCAGTACAGCTTTCTTGTGGTTCCCTG
CACTGGTACTAACAGCTTTGGTAGCCCTGCTGCGCAAACCTGCTTAAATGAATATCATCTTTTTTTCCTACTGACTGGAGCATTTATGGG
CTATAGCTATAGCCTCCTGTATTTTGTTAACAACATGAACTATCTTCCATTTCCCATCATACAGCAATACAAGTTCTTGCGTTTTAGGAG
ATCTCTGCTCTTATTAGTTAAACACAGTTGTGTGGAATCACTGTTCCTGGTTAGAAATTTCTGCATTTTATATTATTTTCTTGGCTATAT
TCCCAAAGCTTGGATTAGCACTGCTATGAACCTTCACATAGATGAGCAGGTTCATAGGCCACTTGACACAGTGAGTGGCCTCTTAAATCT
CTCGTTACTCTACCATGTCTGGCTGTGTGGTGTCTTTCTCCTGACGACTTGGTATGTCTCATGGATACTCTTCAAAATCTATGCCACAGA
GGCTCATGTGTTTCCTGTTCAACCACCATTTGCAGAAGGGTCAGATGAGTGCCTTCCAAAAGTGTTAAATAGCAATCCTCCCCCCATCAT
AAAGTATTTAGCCTTGCAGGACCTGATGTTGCTTTCTCAATATTCTCCTTCACGAAGACAAGAAGTTTTCAGCCTCAGCCAACCAGGTGG
ACATCCCCACAATTGGACAGCCATTTCAAGGGAGTGTTTGAATCTTTTAAATGGTATGACTCAGAAACTGATTCTCTATCAAGAAGCTGC
TGCTACGAATGGGAGAGTGTCTTCATCTTACCCAGTGGAACCTAAGAAATTAAATTCTCCAGAAGAAACTGCTTTTCAGACACCAAAATC
TAGCCAGATGCCTCGGCCTTCAGTGCCACCATTAGTTAAAACATCACTGTTTTCTTCAAAATTATCTACACCTGATGTTGTGAGCCCATT
TGGGACCCCATTTGGCTCTAGTGTAATGAATCGGATGGCTGGAATTTTTGATGTAAACACCTGCTATGGGTCACCGCAAAGTCCTCAGCT
AATAAGAAGGGGGCCAAGATTGTGGACATCAGCTTCTGATCAGCAAATGACTGAATTTTCTAATCCTTCTCCATCTACCTCTATTAGTGC
TGAGGCACCCAGAGGCCTCCATTCAGGCTGTTTTTTCAGATGCCCAAATGCATATTTGGGCATTAGAAGGTCTGTCGCACTTAGTAGCAG
CATCATTTACAGAGGATAGATTTGGAGTTGTCCAGACGACACTACCAGCTATCCTTAATACTTTGTTGACACTGCAAGAGGCAGTCGACA
AGTACTTTAAGCTTCCTCATGCTTCCAGTAAACCACCCCGGATTTCAGGAAGCCTTGTGGACACTTCATATAAAACATTAAGATTTGCAT
TCAGAGCATCACTGAAAACTGCCATCTATCGAATAACTACTACATTTGGTGAACATCTGAATGCTGTGCAAGCATCTGCAGAACATCAGA
AAAGACTTCAACAGTTCTTGGAGTTCAAAGAATAGTTAAGTAATATAAACTGTGTTCATTACACTGCTGATACAACTACAGATGGGACAG
TAAATGTTCAGCATTCTTGGATCAGAAGAAAACGGACTAATTAGATGCTTCCTTTGTCGTGGTGGTTGCTTTGAAAACTATACTTTAATG
GGAGAAATCATGGAAAGAAATTCTCAACAGAATAACTGAAAACTGCCTTTTCTGTACCGATTGCTTTTTGTGTGTGTGGTATAATAAAAT
CTTTATTCAATTTTACAGAAGCATTGATGGCAGTCGAAATGTCTCTAGCTCATATAACTTAATAGTAATAACTAAAAAACTTTTAGAATT
TACTTTTGAAAGGAGGGAAGCCAGTTCTGAAATGAGTATAGGTTGATTTCATAGTCTTCTTAATTAAGAGTTTAGCTCTTTGTAAACTCA
AAATACATAAACTTTTTAAGTGTAGTTTCATTTACTGAAGGATAAAAATGGTAACAGTGCAGCAATATTCACAAAAAATATTGTCTAACG
GACATATTTTGTTAATCTGTTAGGTTGGGTTTTTGTTTCCAGGGACAAATTAAATTTGTATGATTACCCAAAAAAGGGTCTCAGTTTACA
GATGCTAACTCTATATAAAGGAATGTGGAAAAACTCAGTTCTTAAGTTACAAGATTAAAAATTCACATTTGGTCTTTAAGAAACAATTGA
CTGACATCTATGAATTTATTTTGTATCATGCTAGTAAACACGAAGTATTAATGTATGGGTATTTTCCCAGCTAGTTTTGCTTTCTTTTTC
TGGAGCAAAACATTAAGTGATTGCAGAGTTTTTCAAGCAAGAGAAAAAGGTTTGCAAAAAAACCCAGGAAATGTTCCCTTTTTTCCCCAC
CATTCATCTTCATTAGATCAAATTCTGTGAAACTTGTCTGGTCTCTCAAAGGGAGCAGCCTCTGTAGTGTTAAATGGCTAATTAAAATAG
GAAGATCTTTATAGCCAGAAACAACTTAGTCATCAAATAGCAAGTGAAACCAAAACGTCAGAGGGATTACTGTACTTGGAAGTATGTTGT
GTGTCCCAAATGTGAACGAAGTATTGTTAGAATTTATTAGATCAGCTTCTTTGGAGATCAAAGATTGGAAATCCTAGTCATAGATATTCA
CTGGACTGGCTTTGGACTGAAATGCTCCTTTGTAATTCTTTTCCTATTGTCTTTTCCTTCTAGTGTCCCAAAATATTTTCTTTAAAGTCA
GCACAGTACTGTATATGAATCTTTAATGTGGTATCATATATGTCTACTTTTGTCTGATTCATCGATGTATTATATCTTTATAATTGAATA
TTTTAGCTCCGGGTCCTGTTGCCCCTTCAAGCAGTACATGCCAAATTATAAATAGGTGCTACTGGCCTTGAGCATATCACTGTGGGACAG
TTCCCCAATTGTCAAGTGTTTAGATATGTAGACTATTGCCATTTGTTTTTTTGTTTTGGTTTTGCTTTGTGTCTGAAGCTGAATTGATTT
CTTTTTTTTGAATGTGAAAGTTGAATTTCAAACGTAGTCATTTCTTACAGATGGCCAAGACAGAAAATTGTGGCTAGGTTGACTGAGAAC
TGTTGTCTTCCATGTATTAACACAATTAAGCTTTTTATATTCCACTCTCTGTGCTGACCCTGGCTGAGGCATTTTGGGAGACAAGGACTC
TGAATCTTCTGCTTCCATTAAAGAAGAACTGTGATATTCAACATTGGATTTCTGAGAATAAAGATAGGATGATTCCTTTGAACTTTGACT
TACTTGTATAAAATGTCCAGCTAGGTTAGGTTTTTGCCATTTCCTATATACTTTGGGTAAAGCTACATTTGATGAGCAATGTGAATGTTT
CTGAGAATGTTCATTCCTGTTTTCTCTTAAGAGAATGTGCTGTGTACTAAATACAGGCCACATAGTGTCTGCCTGTTGAAGATCTGGAAA
CTGCCTCCCCAGATCTGTATTGTATTTGGTAGGTAAGGGGGTCAGTTTCTTTTTCTCATTGTGTGTTGATAATCTACACACCATCTGTTG
GAACCAGGGTGTTATTATGGGGAACTCCTCCTGTGTACTAGGAGGAGGACCTTAGGGAGACCAAGAGGAGAGAAGCATTTCCTTTGATGA
AGTCACATCCTGTCTATGAGCCCACTAATGCTGTAACATTGGCCTGAAAGAGAGTGTTCTTTAAAAGCCTTTCTCGGCTGTTAGTATAAA
AACATGATGGTATCAGCTCTTAGCATGTTTGCTTGACCCTTATGGAAGGTATAAATCCACAGAACTTCCTTCCCAGAGAACTGGGAAATT
GTCCTAGAAATAAACCTTGTACAGTTGAGTGGACATGGATAAGCAACAATTTGTTACTTTGCAGGATTTGTTCCTTGGTAATTGTTTGGT
GTGTCATCCTGTAAATATTCATGATAGTCTGTTTATATCCTTTTGTATATCGTTGATACTGGATTGGGTAGAAAAATAAATTGGCAATTT

>3243_3243_2_AK4-NDC1_AK4_chr1_65656512_ENST00000327299_NDC1_chr1_54293846_ENST00000540001_length(amino acids)=603AA_BP=154
MLLGPGAGLRGGVVLKVSPSPCRGGRRVPVRAEGARGRGPRNKVPGASSGAAVGAARLTAPLLAKAMASKLLRAVILGPPGSGKGTVCQR
IAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRRGQHWLLDVVPSIPCSRLALIGKIIHPQQLMHSF
IHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSL
LLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAH
VFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLNLLNGMTQKLILYQEAAAT
NGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIR

--------------------------------------------------------------
>3243_3243_3_AK4-NDC1_AK4_chr1_65656512_ENST00000395334_NDC1_chr1_54293846_ENST00000371429_length(transcript)=4878nt_BP=623nt
AGCCGCCGGGGAGGGGACGAGACGCAGACCACACGTTGCCCACGTGCGAGGACCGGGCAGGGGCTCAGCCCCTAGGCCGCCCGGTGCGTG
GGGCGGCGGGGGCTGGCTTTGAGTCACCCCCGCTTGTGCCAGCTTCCCCGGCTCGGCGGAGACTGGCTTGGGGATGCCTGGCCGCCCGGC
CCCCTTCTCGGACGCGGCGTGGGGAGCGAGCTGGAGTTAAGGATGAAGGGGCGGCCGGCGAGTCCCAGTGAGAGCGGAGGGTGCCAGAGG
TAGGGGGCCGAGAAACAAAGTTCCCGGGGCTTCCTCCGGGGCCGCGGTCGGGGCTGCGCGTTTGACCGCCCCCCTCCTCGCGAAGGCAAT
GGCTTCCAAACTCCTGCGCGCGGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACCGTGTGCCAGAGGATCGCCCAGAACTTTGGTCT
CCAGCATCTCTCCAGCGGCCACTTCTTGCGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAAAG
TCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTGGAGAACAGGCGTGGCCAGCACTGGCTCCTTGATGTTGTGCC
TTCTATTCCTTGCTCCAGACTAGCTCTGATAGGGAAGATCATTCATCCTCAGCAACTCATGCACTCATTTATTCATGCTGCAATGGGAAT
GGTGATGGCCTGGTGTGCTGCAGTGATAACCCAGGGCCAGTACAGCTTTCTTGTGGTTCCCTGCACTGGTACTAACAGCTTTGGTAGCCC
TGCTGCGCAAACCTGCTTAAATGAATATCATCTTTTTTTCCTACTGACTGGAGCATTTATGGGCTATAGCTATAGCCTCCTGTATTTTGT
TAACAACATGAACTATCTTCCATTTCCCATCATACAGCAATACAAGTTCTTGCGTTTTAGGAGATCTCTGCTCTTATTAGTTAAACACAG
TTGTGTGGAATCACTGTTCCTGGTTAGAAATTTCTGCATTTTATATTATTTTCTTGGCTATATTCCCAAAGCTTGGATTAGCACTGCTAT
GAACCTTCACATAGATGAGCAGGTTCATAGGCCACTTGACACAGTGAGTGGCCTCTTAAATCTCTCGTTACTCTACCATGTCTGGCTGTG
TGGTGTCTTTCTCCTGACGACTTGGTATGTCTCATGGATACTCTTCAAAATCTATGCCACAGAGGCTCATGTGTTTCCTGTTCAACCACC
ATTTGCAGAAGGGTCAGATGAGTGCCTTCCAAAAGTGTTAAATAGCAATCCTCCCCCCATCATAAAGTATTTAGCCTTGCAGGACCTGAT
GTTGCTTTCTCAATATTCTCCTTCACGAAGACAAGAAGTTTTCAGCCTCAGCCAACCAGGTGGACATCCCCACAATTGGACAGCCATTTC
AAGGGAGTGTTTGAATCTTTTAAATGGTATGACTCAGAAACTGATTCTCTATCAAGAAGCTGCTGCTACGAATGGGAGAGTGTCTTCATC
TTACCCAGTGGAACCTAAGAAATTAAATTCTCCAGAAGAAACTGCTTTTCAGACACCAAAATCTAGCCAGATGCCTCGGCCTTCAGTGCC
ACCATTAGTTAAAACATCACTGTTTTCTTCAAAATTATCTACACCTGATGTTGTGAGCCCATTTGGGACCCCATTTGGCTCTAGTGTAAT
GAATCGGATGGCTGGAATTTTTGATGTAAACACCTGCTATGGGTCACCGCAAAGTCCTCAGCTAATAAGAAGGGGGCCAAGATTGTGGAC
ATCAGCTTCTGATCAGCAAATGACTGAATTTTCTAATCCTTCTCCATCTACCTCTATTAGTGCTGAGGGTAAGACAATGAGACAACCCAG
TGTGATTTATTCATGGATTCAGAATAAACGTGAACAGATTAAGAATTTCTTGTCAAAACGGGTGCTGATAATGTATTTTTTCAGTAAGCA
CCCAGAGGCCTCCATTCAGGCTGTTTTTTCAGATGCCCAAATGCATATTTGGGCATTAGAAGGTCTGTCGCACTTAGTAGCAGCATCATT
TACAGAGGATAGATTTGGAGTTGTCCAGACGACACTACCAGCTATCCTTAATACTTTGTTGACACTGCAAGAGGCAGTCGACAAGTACTT
TAAGCTTCCTCATGCTTCCAGTAAACCACCCCGGATTTCAGGAAGCCTTGTGGACACTTCATATAAAACATTAAGATTTGCATTCAGAGC
ATCACTGAAAACTGCCATCTATCGAATAACTACTACATTTGGTGAACATCTGAATGCTGTGCAAGCATCTGCAGAACATCAGAAAAGACT
TCAACAGTTCTTGGAGTTCAAAGAATAGTTAAGTAATATAAACTGTGTTCATTACACTGCTGATACAACTACAGATGGGACAGTAAATGT
TCAGCATTCTTGGATCAGAAGAAAACGGACTAATTAGATGCTTCCTTTGTCGTGGTGGTTGCTTTGAAAACTATACTTTAATGGGAGAAA
TCATGGAAAGAAATTCTCAACAGAATAACTGAAAACTGCCTTTTCTGTACCGATTGCTTTTTGTGTGTGTGGTATAATAAAATCTTTATT
CAATTTTACAGAAGCATTGATGGCAGTCGAAATGTCTCTAGCTCATATAACTTAATAGTAATAACTAAAAAACTTTTAGAATTTACTTTT
GAAAGGAGGGAAGCCAGTTCTGAAATGAGTATAGGTTGATTTCATAGTCTTCTTAATTAAGAGTTTAGCTCTTTGTAAACTCAAAATACA
TAAACTTTTTAAGTGTAGTTTCATTTACTGAAGGATAAAAATGGTAACAGTGCAGCAATATTCACAAAAAATATTGTCTAACGGACATAT
TTTGTTAATCTGTTAGGTTGGGTTTTTGTTTCCAGGGACAAATTAAATTTGTATGATTACCCAAAAAAGGGTCTCAGTTTACAGATGCTA
ACTCTATATAAAGGAATGTGGAAAAACTCAGTTCTTAAGTTACAAGATTAAAAATTCACATTTGGTCTTTAAGAAACAATTGACTGACAT
CTATGAATTTATTTTGTATCATGCTAGTAAACACGAAGTATTAATGTATGGGTATTTTCCCAGCTAGTTTTGCTTTCTTTTTCTGGAGCA
AAACATTAAGTGATTGCAGAGTTTTTCAAGCAAGAGAAAAAGGTTTGCAAAAAAACCCAGGAAATGTTCCCTTTTTTCCCCACCATTCAT
CTTCATTAGATCAAATTCTGTGAAACTTGTCTGGTCTCTCAAAGGGAGCAGCCTCTGTAGTGTTAAATGGCTAATTAAAATAGGAAGATC
TTTATAGCCAGAAACAACTTAGTCATCAAATAGCAAGTGAAACCAAAACGTCAGAGGGATTACTGTACTTGGAAGTATGTTGTGTGTCCC
AAATGTGAACGAAGTATTGTTAGAATTTATTAGATCAGCTTCTTTGGAGATCAAAGATTGGAAATCCTAGTCATAGATATTCACTGGACT
GGCTTTGGACTGAAATGCTCCTTTGTAATTCTTTTCCTATTGTCTTTTCCTTCTAGTGTCCCAAAATATTTTCTTTAAAGTCAGCACAGT
ACTGTATATGAATCTTTAATGTGGTATCATATATGTCTACTTTTGTCTGATTCATCGATGTATTATATCTTTATAATTGAATATTTTAGC
TCCGGGTCCTGTTGCCCCTTCAAGCAGTACATGCCAAATTATAAATAGGTGCTACTGGCCTTGAGCATATCACTGTGGGACAGTTCCCCA
ATTGTCAAGTGTTTAGATATGTAGACTATTGCCATTTGTTTTTTTGTTTTGGTTTTGCTTTGTGTCTGAAGCTGAATTGATTTCTTTTTT
TTGAATGTGAAAGTTGAATTTCAAACGTAGTCATTTCTTACAGATGGCCAAGACAGAAAATTGTGGCTAGGTTGACTGAGAACTGTTGTC
TTCCATGTATTAACACAATTAAGCTTTTTATATTCCACTCTCTGTGCTGACCCTGGCTGAGGCATTTTGGGAGACAAGGACTCTGAATCT
TCTGCTTCCATTAAAGAAGAACTGTGATATTCAACATTGGATTTCTGAGAATAAAGATAGGATGATTCCTTTGAACTTTGACTTACTTGT
ATAAAATGTCCAGCTAGGTTAGGTTTTTGCCATTTCCTATATACTTTGGGTAAAGCTACATTTGATGAGCAATGTGAATGTTTCTGAGAA
TGTTCATTCCTGTTTTCTCTTAAGAGAATGTGCTGTGTACTAAATACAGGCCACATAGTGTCTGCCTGTTGAAGATCTGGAAACTGCCTC
CCCAGATCTGTATTGTATTTGGTAGGTAAGGGGGTCAGTTTCTTTTTCTCATTGTGTGTTGATAATCTACACACCATCTGTTGGAACCAG
GGTGTTATTATGGGGAACTCCTCCTGTGTACTAGGAGGAGGACCTTAGGGAGACCAAGAGGAGAGAAGCATTTCCTTTGATGAAGTCACA
TCCTGTCTATGAGCCCACTAATGCTGTAACATTGGCCTGAAAGAGAGTGTTCTTTAAAAGCCTTTCTCGGCTGTTAGTATAAAAACATGA
TGGTATCAGCTCTTAGCATGTTTGCTTGACCCTTATGGAAGGTATAAATCCACAGAACTTCCTTCCCAGAGAACTGGGAAATTGTCCTAG
AAATAAACCTTGTACAGTTGAGTGGACATGGATAAGCAACAATTTGTTACTTTGCAGGATTTGTTCCTTGGTAATTGTTTGGTGTGTCAT
CCTGTAAATATTCATGATAGTCTGTTTATATCCTTTTGTATATCGTTGATACTGGATTGGGTAGAAAAATAAATTGGCAATTTAAAAAAA

>3243_3243_3_AK4-NDC1_AK4_chr1_65656512_ENST00000395334_NDC1_chr1_54293846_ENST00000371429_length(amino acids)=678AA_BP=97
MTAPLLAKAMASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRR
GQHWLLDVVPSIPCSRLALIGKIIHPQQLMHSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFM
GYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLN
LSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHVFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPG
GHPHNWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSP
FGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRRGPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKR
VLIMYFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRISGSLVDTS

--------------------------------------------------------------
>3243_3243_4_AK4-NDC1_AK4_chr1_65656512_ENST00000395334_NDC1_chr1_54293846_ENST00000540001_length(transcript)=4765nt_BP=623nt
AGCCGCCGGGGAGGGGACGAGACGCAGACCACACGTTGCCCACGTGCGAGGACCGGGCAGGGGCTCAGCCCCTAGGCCGCCCGGTGCGTG
GGGCGGCGGGGGCTGGCTTTGAGTCACCCCCGCTTGTGCCAGCTTCCCCGGCTCGGCGGAGACTGGCTTGGGGATGCCTGGCCGCCCGGC
CCCCTTCTCGGACGCGGCGTGGGGAGCGAGCTGGAGTTAAGGATGAAGGGGCGGCCGGCGAGTCCCAGTGAGAGCGGAGGGTGCCAGAGG
TAGGGGGCCGAGAAACAAAGTTCCCGGGGCTTCCTCCGGGGCCGCGGTCGGGGCTGCGCGTTTGACCGCCCCCCTCCTCGCGAAGGCAAT
GGCTTCCAAACTCCTGCGCGCGGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACCGTGTGCCAGAGGATCGCCCAGAACTTTGGTCT
CCAGCATCTCTCCAGCGGCCACTTCTTGCGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAAAG
TCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTGGAGAACAGGCGTGGCCAGCACTGGCTCCTTGATGTTGTGCC
TTCTATTCCTTGCTCCAGACTAGCTCTGATAGGGAAGATCATTCATCCTCAGCAACTCATGCACTCATTTATTCATGCTGCAATGGGAAT
GGTGATGGCCTGGTGTGCTGCAGTGATAACCCAGGGCCAGTACAGCTTTCTTGTGGTTCCCTGCACTGGTACTAACAGCTTTGGTAGCCC
TGCTGCGCAAACCTGCTTAAATGAATATCATCTTTTTTTCCTACTGACTGGAGCATTTATGGGCTATAGCTATAGCCTCCTGTATTTTGT
TAACAACATGAACTATCTTCCATTTCCCATCATACAGCAATACAAGTTCTTGCGTTTTAGGAGATCTCTGCTCTTATTAGTTAAACACAG
TTGTGTGGAATCACTGTTCCTGGTTAGAAATTTCTGCATTTTATATTATTTTCTTGGCTATATTCCCAAAGCTTGGATTAGCACTGCTAT
GAACCTTCACATAGATGAGCAGGTTCATAGGCCACTTGACACAGTGAGTGGCCTCTTAAATCTCTCGTTACTCTACCATGTCTGGCTGTG
TGGTGTCTTTCTCCTGACGACTTGGTATGTCTCATGGATACTCTTCAAAATCTATGCCACAGAGGCTCATGTGTTTCCTGTTCAACCACC
ATTTGCAGAAGGGTCAGATGAGTGCCTTCCAAAAGTGTTAAATAGCAATCCTCCCCCCATCATAAAGTATTTAGCCTTGCAGGACCTGAT
GTTGCTTTCTCAATATTCTCCTTCACGAAGACAAGAAGTTTTCAGCCTCAGCCAACCAGGTGGACATCCCCACAATTGGACAGCCATTTC
AAGGGAGTGTTTGAATCTTTTAAATGGTATGACTCAGAAACTGATTCTCTATCAAGAAGCTGCTGCTACGAATGGGAGAGTGTCTTCATC
TTACCCAGTGGAACCTAAGAAATTAAATTCTCCAGAAGAAACTGCTTTTCAGACACCAAAATCTAGCCAGATGCCTCGGCCTTCAGTGCC
ACCATTAGTTAAAACATCACTGTTTTCTTCAAAATTATCTACACCTGATGTTGTGAGCCCATTTGGGACCCCATTTGGCTCTAGTGTAAT
GAATCGGATGGCTGGAATTTTTGATGTAAACACCTGCTATGGGTCACCGCAAAGTCCTCAGCTAATAAGAAGGGGGCCAAGATTGTGGAC
ATCAGCTTCTGATCAGCAAATGACTGAATTTTCTAATCCTTCTCCATCTACCTCTATTAGTGCTGAGGCACCCAGAGGCCTCCATTCAGG
CTGTTTTTTCAGATGCCCAAATGCATATTTGGGCATTAGAAGGTCTGTCGCACTTAGTAGCAGCATCATTTACAGAGGATAGATTTGGAG
TTGTCCAGACGACACTACCAGCTATCCTTAATACTTTGTTGACACTGCAAGAGGCAGTCGACAAGTACTTTAAGCTTCCTCATGCTTCCA
GTAAACCACCCCGGATTTCAGGAAGCCTTGTGGACACTTCATATAAAACATTAAGATTTGCATTCAGAGCATCACTGAAAACTGCCATCT
ATCGAATAACTACTACATTTGGTGAACATCTGAATGCTGTGCAAGCATCTGCAGAACATCAGAAAAGACTTCAACAGTTCTTGGAGTTCA
AAGAATAGTTAAGTAATATAAACTGTGTTCATTACACTGCTGATACAACTACAGATGGGACAGTAAATGTTCAGCATTCTTGGATCAGAA
GAAAACGGACTAATTAGATGCTTCCTTTGTCGTGGTGGTTGCTTTGAAAACTATACTTTAATGGGAGAAATCATGGAAAGAAATTCTCAA
CAGAATAACTGAAAACTGCCTTTTCTGTACCGATTGCTTTTTGTGTGTGTGGTATAATAAAATCTTTATTCAATTTTACAGAAGCATTGA
TGGCAGTCGAAATGTCTCTAGCTCATATAACTTAATAGTAATAACTAAAAAACTTTTAGAATTTACTTTTGAAAGGAGGGAAGCCAGTTC
TGAAATGAGTATAGGTTGATTTCATAGTCTTCTTAATTAAGAGTTTAGCTCTTTGTAAACTCAAAATACATAAACTTTTTAAGTGTAGTT
TCATTTACTGAAGGATAAAAATGGTAACAGTGCAGCAATATTCACAAAAAATATTGTCTAACGGACATATTTTGTTAATCTGTTAGGTTG
GGTTTTTGTTTCCAGGGACAAATTAAATTTGTATGATTACCCAAAAAAGGGTCTCAGTTTACAGATGCTAACTCTATATAAAGGAATGTG
GAAAAACTCAGTTCTTAAGTTACAAGATTAAAAATTCACATTTGGTCTTTAAGAAACAATTGACTGACATCTATGAATTTATTTTGTATC
ATGCTAGTAAACACGAAGTATTAATGTATGGGTATTTTCCCAGCTAGTTTTGCTTTCTTTTTCTGGAGCAAAACATTAAGTGATTGCAGA
GTTTTTCAAGCAAGAGAAAAAGGTTTGCAAAAAAACCCAGGAAATGTTCCCTTTTTTCCCCACCATTCATCTTCATTAGATCAAATTCTG
TGAAACTTGTCTGGTCTCTCAAAGGGAGCAGCCTCTGTAGTGTTAAATGGCTAATTAAAATAGGAAGATCTTTATAGCCAGAAACAACTT
AGTCATCAAATAGCAAGTGAAACCAAAACGTCAGAGGGATTACTGTACTTGGAAGTATGTTGTGTGTCCCAAATGTGAACGAAGTATTGT
TAGAATTTATTAGATCAGCTTCTTTGGAGATCAAAGATTGGAAATCCTAGTCATAGATATTCACTGGACTGGCTTTGGACTGAAATGCTC
CTTTGTAATTCTTTTCCTATTGTCTTTTCCTTCTAGTGTCCCAAAATATTTTCTTTAAAGTCAGCACAGTACTGTATATGAATCTTTAAT
GTGGTATCATATATGTCTACTTTTGTCTGATTCATCGATGTATTATATCTTTATAATTGAATATTTTAGCTCCGGGTCCTGTTGCCCCTT
CAAGCAGTACATGCCAAATTATAAATAGGTGCTACTGGCCTTGAGCATATCACTGTGGGACAGTTCCCCAATTGTCAAGTGTTTAGATAT
GTAGACTATTGCCATTTGTTTTTTTGTTTTGGTTTTGCTTTGTGTCTGAAGCTGAATTGATTTCTTTTTTTTGAATGTGAAAGTTGAATT
TCAAACGTAGTCATTTCTTACAGATGGCCAAGACAGAAAATTGTGGCTAGGTTGACTGAGAACTGTTGTCTTCCATGTATTAACACAATT
AAGCTTTTTATATTCCACTCTCTGTGCTGACCCTGGCTGAGGCATTTTGGGAGACAAGGACTCTGAATCTTCTGCTTCCATTAAAGAAGA
ACTGTGATATTCAACATTGGATTTCTGAGAATAAAGATAGGATGATTCCTTTGAACTTTGACTTACTTGTATAAAATGTCCAGCTAGGTT
AGGTTTTTGCCATTTCCTATATACTTTGGGTAAAGCTACATTTGATGAGCAATGTGAATGTTTCTGAGAATGTTCATTCCTGTTTTCTCT
TAAGAGAATGTGCTGTGTACTAAATACAGGCCACATAGTGTCTGCCTGTTGAAGATCTGGAAACTGCCTCCCCAGATCTGTATTGTATTT
GGTAGGTAAGGGGGTCAGTTTCTTTTTCTCATTGTGTGTTGATAATCTACACACCATCTGTTGGAACCAGGGTGTTATTATGGGGAACTC
CTCCTGTGTACTAGGAGGAGGACCTTAGGGAGACCAAGAGGAGAGAAGCATTTCCTTTGATGAAGTCACATCCTGTCTATGAGCCCACTA
ATGCTGTAACATTGGCCTGAAAGAGAGTGTTCTTTAAAAGCCTTTCTCGGCTGTTAGTATAAAAACATGATGGTATCAGCTCTTAGCATG
TTTGCTTGACCCTTATGGAAGGTATAAATCCACAGAACTTCCTTCCCAGAGAACTGGGAAATTGTCCTAGAAATAAACCTTGTACAGTTG
AGTGGACATGGATAAGCAACAATTTGTTACTTTGCAGGATTTGTTCCTTGGTAATTGTTTGGTGTGTCATCCTGTAAATATTCATGATAG

>3243_3243_4_AK4-NDC1_AK4_chr1_65656512_ENST00000395334_NDC1_chr1_54293846_ENST00000540001_length(amino acids)=546AA_BP=97
MTAPLLAKAMASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRR
GQHWLLDVVPSIPCSRLALIGKIIHPQQLMHSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFM
GYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLN
LSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHVFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPG
GHPHNWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSP
FGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRRGPRLWTSASDQQMTEFSNPSPSTSISAEAPRGLHSGCFFRCPNAYLGIRRSVALSS

--------------------------------------------------------------
>3243_3243_5_AK4-NDC1_AK4_chr1_65656512_ENST00000545314_NDC1_chr1_54293846_ENST00000371429_length(transcript)=4767nt_BP=512nt
TTACGTAAGGCGCGAGTCCCGCGCGGCCGGCCGGGGCTCCGCGACTGGGCGGGCGGAGGCGGCGCCGCCCTGCAGGATCCGGGCTGGAAG
CCTCTCGGAGTGCTGCCTCCAGCCAAGGGGCGGCCGGCGAGTCCCAGTGAGAGCGGAGGGTGCCAGAGGTAGGGGGCCGAGAAACAAAGT
TCCCGGGGCTTCCTCCGGGGCCGCGGTCGGGGCTGCGCGTTTGACCGCCCCCCTCCTCGCGAAGGCAATGGCTTCCAAACTCCTGCGCGC
GGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACCGTGTGCCAGAGGATCGCCCAGAACTTTGGTCTCCAGCATCTCTCCAGCGGCCA
CTTCTTGCGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAAAGTCTTTTGGTTCCAGACCATGT
GATCACACGCCTAATGATGTCCGAGTTGGAGAACAGGCGTGGCCAGCACTGGCTCCTTGATGTTGTGCCTTCTATTCCTTGCTCCAGACT
AGCTCTGATAGGGAAGATCATTCATCCTCAGCAACTCATGCACTCATTTATTCATGCTGCAATGGGAATGGTGATGGCCTGGTGTGCTGC
AGTGATAACCCAGGGCCAGTACAGCTTTCTTGTGGTTCCCTGCACTGGTACTAACAGCTTTGGTAGCCCTGCTGCGCAAACCTGCTTAAA
TGAATATCATCTTTTTTTCCTACTGACTGGAGCATTTATGGGCTATAGCTATAGCCTCCTGTATTTTGTTAACAACATGAACTATCTTCC
ATTTCCCATCATACAGCAATACAAGTTCTTGCGTTTTAGGAGATCTCTGCTCTTATTAGTTAAACACAGTTGTGTGGAATCACTGTTCCT
GGTTAGAAATTTCTGCATTTTATATTATTTTCTTGGCTATATTCCCAAAGCTTGGATTAGCACTGCTATGAACCTTCACATAGATGAGCA
GGTTCATAGGCCACTTGACACAGTGAGTGGCCTCTTAAATCTCTCGTTACTCTACCATGTCTGGCTGTGTGGTGTCTTTCTCCTGACGAC
TTGGTATGTCTCATGGATACTCTTCAAAATCTATGCCACAGAGGCTCATGTGTTTCCTGTTCAACCACCATTTGCAGAAGGGTCAGATGA
GTGCCTTCCAAAAGTGTTAAATAGCAATCCTCCCCCCATCATAAAGTATTTAGCCTTGCAGGACCTGATGTTGCTTTCTCAATATTCTCC
TTCACGAAGACAAGAAGTTTTCAGCCTCAGCCAACCAGGTGGACATCCCCACAATTGGACAGCCATTTCAAGGGAGTGTTTGAATCTTTT
AAATGGTATGACTCAGAAACTGATTCTCTATCAAGAAGCTGCTGCTACGAATGGGAGAGTGTCTTCATCTTACCCAGTGGAACCTAAGAA
ATTAAATTCTCCAGAAGAAACTGCTTTTCAGACACCAAAATCTAGCCAGATGCCTCGGCCTTCAGTGCCACCATTAGTTAAAACATCACT
GTTTTCTTCAAAATTATCTACACCTGATGTTGTGAGCCCATTTGGGACCCCATTTGGCTCTAGTGTAATGAATCGGATGGCTGGAATTTT
TGATGTAAACACCTGCTATGGGTCACCGCAAAGTCCTCAGCTAATAAGAAGGGGGCCAAGATTGTGGACATCAGCTTCTGATCAGCAAAT
GACTGAATTTTCTAATCCTTCTCCATCTACCTCTATTAGTGCTGAGGGTAAGACAATGAGACAACCCAGTGTGATTTATTCATGGATTCA
GAATAAACGTGAACAGATTAAGAATTTCTTGTCAAAACGGGTGCTGATAATGTATTTTTTCAGTAAGCACCCAGAGGCCTCCATTCAGGC
TGTTTTTTCAGATGCCCAAATGCATATTTGGGCATTAGAAGGTCTGTCGCACTTAGTAGCAGCATCATTTACAGAGGATAGATTTGGAGT
TGTCCAGACGACACTACCAGCTATCCTTAATACTTTGTTGACACTGCAAGAGGCAGTCGACAAGTACTTTAAGCTTCCTCATGCTTCCAG
TAAACCACCCCGGATTTCAGGAAGCCTTGTGGACACTTCATATAAAACATTAAGATTTGCATTCAGAGCATCACTGAAAACTGCCATCTA
TCGAATAACTACTACATTTGGTGAACATCTGAATGCTGTGCAAGCATCTGCAGAACATCAGAAAAGACTTCAACAGTTCTTGGAGTTCAA
AGAATAGTTAAGTAATATAAACTGTGTTCATTACACTGCTGATACAACTACAGATGGGACAGTAAATGTTCAGCATTCTTGGATCAGAAG
AAAACGGACTAATTAGATGCTTCCTTTGTCGTGGTGGTTGCTTTGAAAACTATACTTTAATGGGAGAAATCATGGAAAGAAATTCTCAAC
AGAATAACTGAAAACTGCCTTTTCTGTACCGATTGCTTTTTGTGTGTGTGGTATAATAAAATCTTTATTCAATTTTACAGAAGCATTGAT
GGCAGTCGAAATGTCTCTAGCTCATATAACTTAATAGTAATAACTAAAAAACTTTTAGAATTTACTTTTGAAAGGAGGGAAGCCAGTTCT
GAAATGAGTATAGGTTGATTTCATAGTCTTCTTAATTAAGAGTTTAGCTCTTTGTAAACTCAAAATACATAAACTTTTTAAGTGTAGTTT
CATTTACTGAAGGATAAAAATGGTAACAGTGCAGCAATATTCACAAAAAATATTGTCTAACGGACATATTTTGTTAATCTGTTAGGTTGG
GTTTTTGTTTCCAGGGACAAATTAAATTTGTATGATTACCCAAAAAAGGGTCTCAGTTTACAGATGCTAACTCTATATAAAGGAATGTGG
AAAAACTCAGTTCTTAAGTTACAAGATTAAAAATTCACATTTGGTCTTTAAGAAACAATTGACTGACATCTATGAATTTATTTTGTATCA
TGCTAGTAAACACGAAGTATTAATGTATGGGTATTTTCCCAGCTAGTTTTGCTTTCTTTTTCTGGAGCAAAACATTAAGTGATTGCAGAG
TTTTTCAAGCAAGAGAAAAAGGTTTGCAAAAAAACCCAGGAAATGTTCCCTTTTTTCCCCACCATTCATCTTCATTAGATCAAATTCTGT
GAAACTTGTCTGGTCTCTCAAAGGGAGCAGCCTCTGTAGTGTTAAATGGCTAATTAAAATAGGAAGATCTTTATAGCCAGAAACAACTTA
GTCATCAAATAGCAAGTGAAACCAAAACGTCAGAGGGATTACTGTACTTGGAAGTATGTTGTGTGTCCCAAATGTGAACGAAGTATTGTT
AGAATTTATTAGATCAGCTTCTTTGGAGATCAAAGATTGGAAATCCTAGTCATAGATATTCACTGGACTGGCTTTGGACTGAAATGCTCC
TTTGTAATTCTTTTCCTATTGTCTTTTCCTTCTAGTGTCCCAAAATATTTTCTTTAAAGTCAGCACAGTACTGTATATGAATCTTTAATG
TGGTATCATATATGTCTACTTTTGTCTGATTCATCGATGTATTATATCTTTATAATTGAATATTTTAGCTCCGGGTCCTGTTGCCCCTTC
AAGCAGTACATGCCAAATTATAAATAGGTGCTACTGGCCTTGAGCATATCACTGTGGGACAGTTCCCCAATTGTCAAGTGTTTAGATATG
TAGACTATTGCCATTTGTTTTTTTGTTTTGGTTTTGCTTTGTGTCTGAAGCTGAATTGATTTCTTTTTTTTGAATGTGAAAGTTGAATTT
CAAACGTAGTCATTTCTTACAGATGGCCAAGACAGAAAATTGTGGCTAGGTTGACTGAGAACTGTTGTCTTCCATGTATTAACACAATTA
AGCTTTTTATATTCCACTCTCTGTGCTGACCCTGGCTGAGGCATTTTGGGAGACAAGGACTCTGAATCTTCTGCTTCCATTAAAGAAGAA
CTGTGATATTCAACATTGGATTTCTGAGAATAAAGATAGGATGATTCCTTTGAACTTTGACTTACTTGTATAAAATGTCCAGCTAGGTTA
GGTTTTTGCCATTTCCTATATACTTTGGGTAAAGCTACATTTGATGAGCAATGTGAATGTTTCTGAGAATGTTCATTCCTGTTTTCTCTT
AAGAGAATGTGCTGTGTACTAAATACAGGCCACATAGTGTCTGCCTGTTGAAGATCTGGAAACTGCCTCCCCAGATCTGTATTGTATTTG
GTAGGTAAGGGGGTCAGTTTCTTTTTCTCATTGTGTGTTGATAATCTACACACCATCTGTTGGAACCAGGGTGTTATTATGGGGAACTCC
TCCTGTGTACTAGGAGGAGGACCTTAGGGAGACCAAGAGGAGAGAAGCATTTCCTTTGATGAAGTCACATCCTGTCTATGAGCCCACTAA
TGCTGTAACATTGGCCTGAAAGAGAGTGTTCTTTAAAAGCCTTTCTCGGCTGTTAGTATAAAAACATGATGGTATCAGCTCTTAGCATGT
TTGCTTGACCCTTATGGAAGGTATAAATCCACAGAACTTCCTTCCCAGAGAACTGGGAAATTGTCCTAGAAATAAACCTTGTACAGTTGA
GTGGACATGGATAAGCAACAATTTGTTACTTTGCAGGATTTGTTCCTTGGTAATTGTTTGGTGTGTCATCCTGTAAATATTCATGATAGT

>3243_3243_5_AK4-NDC1_AK4_chr1_65656512_ENST00000545314_NDC1_chr1_54293846_ENST00000371429_length(amino acids)=678AA_BP=97
MTAPLLAKAMASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRR
GQHWLLDVVPSIPCSRLALIGKIIHPQQLMHSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFM
GYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLN
LSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHVFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPG
GHPHNWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSP
FGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRRGPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKR
VLIMYFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRISGSLVDTS

--------------------------------------------------------------
>3243_3243_6_AK4-NDC1_AK4_chr1_65656512_ENST00000545314_NDC1_chr1_54293846_ENST00000540001_length(transcript)=4654nt_BP=512nt
TTACGTAAGGCGCGAGTCCCGCGCGGCCGGCCGGGGCTCCGCGACTGGGCGGGCGGAGGCGGCGCCGCCCTGCAGGATCCGGGCTGGAAG
CCTCTCGGAGTGCTGCCTCCAGCCAAGGGGCGGCCGGCGAGTCCCAGTGAGAGCGGAGGGTGCCAGAGGTAGGGGGCCGAGAAACAAAGT
TCCCGGGGCTTCCTCCGGGGCCGCGGTCGGGGCTGCGCGTTTGACCGCCCCCCTCCTCGCGAAGGCAATGGCTTCCAAACTCCTGCGCGC
GGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACCGTGTGCCAGAGGATCGCCCAGAACTTTGGTCTCCAGCATCTCTCCAGCGGCCA
CTTCTTGCGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAAAGTCTTTTGGTTCCAGACCATGT
GATCACACGCCTAATGATGTCCGAGTTGGAGAACAGGCGTGGCCAGCACTGGCTCCTTGATGTTGTGCCTTCTATTCCTTGCTCCAGACT
AGCTCTGATAGGGAAGATCATTCATCCTCAGCAACTCATGCACTCATTTATTCATGCTGCAATGGGAATGGTGATGGCCTGGTGTGCTGC
AGTGATAACCCAGGGCCAGTACAGCTTTCTTGTGGTTCCCTGCACTGGTACTAACAGCTTTGGTAGCCCTGCTGCGCAAACCTGCTTAAA
TGAATATCATCTTTTTTTCCTACTGACTGGAGCATTTATGGGCTATAGCTATAGCCTCCTGTATTTTGTTAACAACATGAACTATCTTCC
ATTTCCCATCATACAGCAATACAAGTTCTTGCGTTTTAGGAGATCTCTGCTCTTATTAGTTAAACACAGTTGTGTGGAATCACTGTTCCT
GGTTAGAAATTTCTGCATTTTATATTATTTTCTTGGCTATATTCCCAAAGCTTGGATTAGCACTGCTATGAACCTTCACATAGATGAGCA
GGTTCATAGGCCACTTGACACAGTGAGTGGCCTCTTAAATCTCTCGTTACTCTACCATGTCTGGCTGTGTGGTGTCTTTCTCCTGACGAC
TTGGTATGTCTCATGGATACTCTTCAAAATCTATGCCACAGAGGCTCATGTGTTTCCTGTTCAACCACCATTTGCAGAAGGGTCAGATGA
GTGCCTTCCAAAAGTGTTAAATAGCAATCCTCCCCCCATCATAAAGTATTTAGCCTTGCAGGACCTGATGTTGCTTTCTCAATATTCTCC
TTCACGAAGACAAGAAGTTTTCAGCCTCAGCCAACCAGGTGGACATCCCCACAATTGGACAGCCATTTCAAGGGAGTGTTTGAATCTTTT
AAATGGTATGACTCAGAAACTGATTCTCTATCAAGAAGCTGCTGCTACGAATGGGAGAGTGTCTTCATCTTACCCAGTGGAACCTAAGAA
ATTAAATTCTCCAGAAGAAACTGCTTTTCAGACACCAAAATCTAGCCAGATGCCTCGGCCTTCAGTGCCACCATTAGTTAAAACATCACT
GTTTTCTTCAAAATTATCTACACCTGATGTTGTGAGCCCATTTGGGACCCCATTTGGCTCTAGTGTAATGAATCGGATGGCTGGAATTTT
TGATGTAAACACCTGCTATGGGTCACCGCAAAGTCCTCAGCTAATAAGAAGGGGGCCAAGATTGTGGACATCAGCTTCTGATCAGCAAAT
GACTGAATTTTCTAATCCTTCTCCATCTACCTCTATTAGTGCTGAGGCACCCAGAGGCCTCCATTCAGGCTGTTTTTTCAGATGCCCAAA
TGCATATTTGGGCATTAGAAGGTCTGTCGCACTTAGTAGCAGCATCATTTACAGAGGATAGATTTGGAGTTGTCCAGACGACACTACCAG
CTATCCTTAATACTTTGTTGACACTGCAAGAGGCAGTCGACAAGTACTTTAAGCTTCCTCATGCTTCCAGTAAACCACCCCGGATTTCAG
GAAGCCTTGTGGACACTTCATATAAAACATTAAGATTTGCATTCAGAGCATCACTGAAAACTGCCATCTATCGAATAACTACTACATTTG
GTGAACATCTGAATGCTGTGCAAGCATCTGCAGAACATCAGAAAAGACTTCAACAGTTCTTGGAGTTCAAAGAATAGTTAAGTAATATAA
ACTGTGTTCATTACACTGCTGATACAACTACAGATGGGACAGTAAATGTTCAGCATTCTTGGATCAGAAGAAAACGGACTAATTAGATGC
TTCCTTTGTCGTGGTGGTTGCTTTGAAAACTATACTTTAATGGGAGAAATCATGGAAAGAAATTCTCAACAGAATAACTGAAAACTGCCT
TTTCTGTACCGATTGCTTTTTGTGTGTGTGGTATAATAAAATCTTTATTCAATTTTACAGAAGCATTGATGGCAGTCGAAATGTCTCTAG
CTCATATAACTTAATAGTAATAACTAAAAAACTTTTAGAATTTACTTTTGAAAGGAGGGAAGCCAGTTCTGAAATGAGTATAGGTTGATT
TCATAGTCTTCTTAATTAAGAGTTTAGCTCTTTGTAAACTCAAAATACATAAACTTTTTAAGTGTAGTTTCATTTACTGAAGGATAAAAA
TGGTAACAGTGCAGCAATATTCACAAAAAATATTGTCTAACGGACATATTTTGTTAATCTGTTAGGTTGGGTTTTTGTTTCCAGGGACAA
ATTAAATTTGTATGATTACCCAAAAAAGGGTCTCAGTTTACAGATGCTAACTCTATATAAAGGAATGTGGAAAAACTCAGTTCTTAAGTT
ACAAGATTAAAAATTCACATTTGGTCTTTAAGAAACAATTGACTGACATCTATGAATTTATTTTGTATCATGCTAGTAAACACGAAGTAT
TAATGTATGGGTATTTTCCCAGCTAGTTTTGCTTTCTTTTTCTGGAGCAAAACATTAAGTGATTGCAGAGTTTTTCAAGCAAGAGAAAAA
GGTTTGCAAAAAAACCCAGGAAATGTTCCCTTTTTTCCCCACCATTCATCTTCATTAGATCAAATTCTGTGAAACTTGTCTGGTCTCTCA
AAGGGAGCAGCCTCTGTAGTGTTAAATGGCTAATTAAAATAGGAAGATCTTTATAGCCAGAAACAACTTAGTCATCAAATAGCAAGTGAA
ACCAAAACGTCAGAGGGATTACTGTACTTGGAAGTATGTTGTGTGTCCCAAATGTGAACGAAGTATTGTTAGAATTTATTAGATCAGCTT
CTTTGGAGATCAAAGATTGGAAATCCTAGTCATAGATATTCACTGGACTGGCTTTGGACTGAAATGCTCCTTTGTAATTCTTTTCCTATT
GTCTTTTCCTTCTAGTGTCCCAAAATATTTTCTTTAAAGTCAGCACAGTACTGTATATGAATCTTTAATGTGGTATCATATATGTCTACT
TTTGTCTGATTCATCGATGTATTATATCTTTATAATTGAATATTTTAGCTCCGGGTCCTGTTGCCCCTTCAAGCAGTACATGCCAAATTA
TAAATAGGTGCTACTGGCCTTGAGCATATCACTGTGGGACAGTTCCCCAATTGTCAAGTGTTTAGATATGTAGACTATTGCCATTTGTTT
TTTTGTTTTGGTTTTGCTTTGTGTCTGAAGCTGAATTGATTTCTTTTTTTTGAATGTGAAAGTTGAATTTCAAACGTAGTCATTTCTTAC
AGATGGCCAAGACAGAAAATTGTGGCTAGGTTGACTGAGAACTGTTGTCTTCCATGTATTAACACAATTAAGCTTTTTATATTCCACTCT
CTGTGCTGACCCTGGCTGAGGCATTTTGGGAGACAAGGACTCTGAATCTTCTGCTTCCATTAAAGAAGAACTGTGATATTCAACATTGGA
TTTCTGAGAATAAAGATAGGATGATTCCTTTGAACTTTGACTTACTTGTATAAAATGTCCAGCTAGGTTAGGTTTTTGCCATTTCCTATA
TACTTTGGGTAAAGCTACATTTGATGAGCAATGTGAATGTTTCTGAGAATGTTCATTCCTGTTTTCTCTTAAGAGAATGTGCTGTGTACT
AAATACAGGCCACATAGTGTCTGCCTGTTGAAGATCTGGAAACTGCCTCCCCAGATCTGTATTGTATTTGGTAGGTAAGGGGGTCAGTTT
CTTTTTCTCATTGTGTGTTGATAATCTACACACCATCTGTTGGAACCAGGGTGTTATTATGGGGAACTCCTCCTGTGTACTAGGAGGAGG
ACCTTAGGGAGACCAAGAGGAGAGAAGCATTTCCTTTGATGAAGTCACATCCTGTCTATGAGCCCACTAATGCTGTAACATTGGCCTGAA
AGAGAGTGTTCTTTAAAAGCCTTTCTCGGCTGTTAGTATAAAAACATGATGGTATCAGCTCTTAGCATGTTTGCTTGACCCTTATGGAAG
GTATAAATCCACAGAACTTCCTTCCCAGAGAACTGGGAAATTGTCCTAGAAATAAACCTTGTACAGTTGAGTGGACATGGATAAGCAACA
ATTTGTTACTTTGCAGGATTTGTTCCTTGGTAATTGTTTGGTGTGTCATCCTGTAAATATTCATGATAGTCTGTTTATATCCTTTTGTAT

>3243_3243_6_AK4-NDC1_AK4_chr1_65656512_ENST00000545314_NDC1_chr1_54293846_ENST00000540001_length(amino acids)=546AA_BP=97
MTAPLLAKAMASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRR
GQHWLLDVVPSIPCSRLALIGKIIHPQQLMHSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFM
GYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLN
LSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHVFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPG
GHPHNWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSP
FGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRRGPRLWTSASDQQMTEFSNPSPSTSISAEAPRGLHSGCFFRCPNAYLGIRRSVALSS

--------------------------------------------------------------
>3243_3243_7_AK4-NDC1_AK4_chr1_65656512_ENST00000546702_NDC1_chr1_54293846_ENST00000371429_length(transcript)=4469nt_BP=214nt
GTGTTTATTTGATTGCTTTTGGTGGCGAGGCGCGGGGCTCGGGCTCGTCGCGCGCCCCATGGCCGGGGAGCGCATCCGCCAACCCCGGGC
GGAGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAAAGTCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTG
GAGAACAGGCGTGGCCAGCACTGGCTCCTTGATGTTGTGCCTTCTATTCCTTGCTCCAGACTAGCTCTGATAGGGAAGATCATTCATCCT
CAGCAACTCATGCACTCATTTATTCATGCTGCAATGGGAATGGTGATGGCCTGGTGTGCTGCAGTGATAACCCAGGGCCAGTACAGCTTT
CTTGTGGTTCCCTGCACTGGTACTAACAGCTTTGGTAGCCCTGCTGCGCAAACCTGCTTAAATGAATATCATCTTTTTTTCCTACTGACT
GGAGCATTTATGGGCTATAGCTATAGCCTCCTGTATTTTGTTAACAACATGAACTATCTTCCATTTCCCATCATACAGCAATACAAGTTC
TTGCGTTTTAGGAGATCTCTGCTCTTATTAGTTAAACACAGTTGTGTGGAATCACTGTTCCTGGTTAGAAATTTCTGCATTTTATATTAT
TTTCTTGGCTATATTCCCAAAGCTTGGATTAGCACTGCTATGAACCTTCACATAGATGAGCAGGTTCATAGGCCACTTGACACAGTGAGT
GGCCTCTTAAATCTCTCGTTACTCTACCATGTCTGGCTGTGTGGTGTCTTTCTCCTGACGACTTGGTATGTCTCATGGATACTCTTCAAA
ATCTATGCCACAGAGGCTCATGTGTTTCCTGTTCAACCACCATTTGCAGAAGGGTCAGATGAGTGCCTTCCAAAAGTGTTAAATAGCAAT
CCTCCCCCCATCATAAAGTATTTAGCCTTGCAGGACCTGATGTTGCTTTCTCAATATTCTCCTTCACGAAGACAAGAAGTTTTCAGCCTC
AGCCAACCAGGTGGACATCCCCACAATTGGACAGCCATTTCAAGGGAGTGTTTGAATCTTTTAAATGGTATGACTCAGAAACTGATTCTC
TATCAAGAAGCTGCTGCTACGAATGGGAGAGTGTCTTCATCTTACCCAGTGGAACCTAAGAAATTAAATTCTCCAGAAGAAACTGCTTTT
CAGACACCAAAATCTAGCCAGATGCCTCGGCCTTCAGTGCCACCATTAGTTAAAACATCACTGTTTTCTTCAAAATTATCTACACCTGAT
GTTGTGAGCCCATTTGGGACCCCATTTGGCTCTAGTGTAATGAATCGGATGGCTGGAATTTTTGATGTAAACACCTGCTATGGGTCACCG
CAAAGTCCTCAGCTAATAAGAAGGGGGCCAAGATTGTGGACATCAGCTTCTGATCAGCAAATGACTGAATTTTCTAATCCTTCTCCATCT
ACCTCTATTAGTGCTGAGGGTAAGACAATGAGACAACCCAGTGTGATTTATTCATGGATTCAGAATAAACGTGAACAGATTAAGAATTTC
TTGTCAAAACGGGTGCTGATAATGTATTTTTTCAGTAAGCACCCAGAGGCCTCCATTCAGGCTGTTTTTTCAGATGCCCAAATGCATATT
TGGGCATTAGAAGGTCTGTCGCACTTAGTAGCAGCATCATTTACAGAGGATAGATTTGGAGTTGTCCAGACGACACTACCAGCTATCCTT
AATACTTTGTTGACACTGCAAGAGGCAGTCGACAAGTACTTTAAGCTTCCTCATGCTTCCAGTAAACCACCCCGGATTTCAGGAAGCCTT
GTGGACACTTCATATAAAACATTAAGATTTGCATTCAGAGCATCACTGAAAACTGCCATCTATCGAATAACTACTACATTTGGTGAACAT
CTGAATGCTGTGCAAGCATCTGCAGAACATCAGAAAAGACTTCAACAGTTCTTGGAGTTCAAAGAATAGTTAAGTAATATAAACTGTGTT
CATTACACTGCTGATACAACTACAGATGGGACAGTAAATGTTCAGCATTCTTGGATCAGAAGAAAACGGACTAATTAGATGCTTCCTTTG
TCGTGGTGGTTGCTTTGAAAACTATACTTTAATGGGAGAAATCATGGAAAGAAATTCTCAACAGAATAACTGAAAACTGCCTTTTCTGTA
CCGATTGCTTTTTGTGTGTGTGGTATAATAAAATCTTTATTCAATTTTACAGAAGCATTGATGGCAGTCGAAATGTCTCTAGCTCATATA
ACTTAATAGTAATAACTAAAAAACTTTTAGAATTTACTTTTGAAAGGAGGGAAGCCAGTTCTGAAATGAGTATAGGTTGATTTCATAGTC
TTCTTAATTAAGAGTTTAGCTCTTTGTAAACTCAAAATACATAAACTTTTTAAGTGTAGTTTCATTTACTGAAGGATAAAAATGGTAACA
GTGCAGCAATATTCACAAAAAATATTGTCTAACGGACATATTTTGTTAATCTGTTAGGTTGGGTTTTTGTTTCCAGGGACAAATTAAATT
TGTATGATTACCCAAAAAAGGGTCTCAGTTTACAGATGCTAACTCTATATAAAGGAATGTGGAAAAACTCAGTTCTTAAGTTACAAGATT
AAAAATTCACATTTGGTCTTTAAGAAACAATTGACTGACATCTATGAATTTATTTTGTATCATGCTAGTAAACACGAAGTATTAATGTAT
GGGTATTTTCCCAGCTAGTTTTGCTTTCTTTTTCTGGAGCAAAACATTAAGTGATTGCAGAGTTTTTCAAGCAAGAGAAAAAGGTTTGCA
AAAAAACCCAGGAAATGTTCCCTTTTTTCCCCACCATTCATCTTCATTAGATCAAATTCTGTGAAACTTGTCTGGTCTCTCAAAGGGAGC
AGCCTCTGTAGTGTTAAATGGCTAATTAAAATAGGAAGATCTTTATAGCCAGAAACAACTTAGTCATCAAATAGCAAGTGAAACCAAAAC
GTCAGAGGGATTACTGTACTTGGAAGTATGTTGTGTGTCCCAAATGTGAACGAAGTATTGTTAGAATTTATTAGATCAGCTTCTTTGGAG
ATCAAAGATTGGAAATCCTAGTCATAGATATTCACTGGACTGGCTTTGGACTGAAATGCTCCTTTGTAATTCTTTTCCTATTGTCTTTTC
CTTCTAGTGTCCCAAAATATTTTCTTTAAAGTCAGCACAGTACTGTATATGAATCTTTAATGTGGTATCATATATGTCTACTTTTGTCTG
ATTCATCGATGTATTATATCTTTATAATTGAATATTTTAGCTCCGGGTCCTGTTGCCCCTTCAAGCAGTACATGCCAAATTATAAATAGG
TGCTACTGGCCTTGAGCATATCACTGTGGGACAGTTCCCCAATTGTCAAGTGTTTAGATATGTAGACTATTGCCATTTGTTTTTTTGTTT
TGGTTTTGCTTTGTGTCTGAAGCTGAATTGATTTCTTTTTTTTGAATGTGAAAGTTGAATTTCAAACGTAGTCATTTCTTACAGATGGCC
AAGACAGAAAATTGTGGCTAGGTTGACTGAGAACTGTTGTCTTCCATGTATTAACACAATTAAGCTTTTTATATTCCACTCTCTGTGCTG
ACCCTGGCTGAGGCATTTTGGGAGACAAGGACTCTGAATCTTCTGCTTCCATTAAAGAAGAACTGTGATATTCAACATTGGATTTCTGAG
AATAAAGATAGGATGATTCCTTTGAACTTTGACTTACTTGTATAAAATGTCCAGCTAGGTTAGGTTTTTGCCATTTCCTATATACTTTGG
GTAAAGCTACATTTGATGAGCAATGTGAATGTTTCTGAGAATGTTCATTCCTGTTTTCTCTTAAGAGAATGTGCTGTGTACTAAATACAG
GCCACATAGTGTCTGCCTGTTGAAGATCTGGAAACTGCCTCCCCAGATCTGTATTGTATTTGGTAGGTAAGGGGGTCAGTTTCTTTTTCT
CATTGTGTGTTGATAATCTACACACCATCTGTTGGAACCAGGGTGTTATTATGGGGAACTCCTCCTGTGTACTAGGAGGAGGACCTTAGG
GAGACCAAGAGGAGAGAAGCATTTCCTTTGATGAAGTCACATCCTGTCTATGAGCCCACTAATGCTGTAACATTGGCCTGAAAGAGAGTG
TTCTTTAAAAGCCTTTCTCGGCTGTTAGTATAAAAACATGATGGTATCAGCTCTTAGCATGTTTGCTTGACCCTTATGGAAGGTATAAAT
CCACAGAACTTCCTTCCCAGAGAACTGGGAAATTGTCCTAGAAATAAACCTTGTACAGTTGAGTGGACATGGATAAGCAACAATTTGTTA
CTTTGCAGGATTTGTTCCTTGGTAATTGTTTGGTGTGTCATCCTGTAAATATTCATGATAGTCTGTTTATATCCTTTTGTATATCGTTGA

>3243_3243_7_AK4-NDC1_AK4_chr1_65656512_ENST00000546702_NDC1_chr1_54293846_ENST00000371429_length(amino acids)=648AA_BP=67
MLLVARRGARARRAPHGRGAHPPTPGGEVGEMAKQYIEKSLLVPDHVITRLMMSELENRRGQHWLLDVVPSIPCSRLALIGKIIHPQQLM
HSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSYSLLYFVNNMNYLPFPIIQQYKFLRFR
RSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYAT
EAHVFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLNLLNGMTQKLILYQEA
AATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQ
LIRRGPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIMYFFSKHPEASIQAVFSDAQMHIWALE
GLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAV

--------------------------------------------------------------
>3243_3243_8_AK4-NDC1_AK4_chr1_65656512_ENST00000546702_NDC1_chr1_54293846_ENST00000540001_length(transcript)=4356nt_BP=214nt
GTGTTTATTTGATTGCTTTTGGTGGCGAGGCGCGGGGCTCGGGCTCGTCGCGCGCCCCATGGCCGGGGAGCGCATCCGCCAACCCCGGGC
GGAGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAAAGTCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTG
GAGAACAGGCGTGGCCAGCACTGGCTCCTTGATGTTGTGCCTTCTATTCCTTGCTCCAGACTAGCTCTGATAGGGAAGATCATTCATCCT
CAGCAACTCATGCACTCATTTATTCATGCTGCAATGGGAATGGTGATGGCCTGGTGTGCTGCAGTGATAACCCAGGGCCAGTACAGCTTT
CTTGTGGTTCCCTGCACTGGTACTAACAGCTTTGGTAGCCCTGCTGCGCAAACCTGCTTAAATGAATATCATCTTTTTTTCCTACTGACT
GGAGCATTTATGGGCTATAGCTATAGCCTCCTGTATTTTGTTAACAACATGAACTATCTTCCATTTCCCATCATACAGCAATACAAGTTC
TTGCGTTTTAGGAGATCTCTGCTCTTATTAGTTAAACACAGTTGTGTGGAATCACTGTTCCTGGTTAGAAATTTCTGCATTTTATATTAT
TTTCTTGGCTATATTCCCAAAGCTTGGATTAGCACTGCTATGAACCTTCACATAGATGAGCAGGTTCATAGGCCACTTGACACAGTGAGT
GGCCTCTTAAATCTCTCGTTACTCTACCATGTCTGGCTGTGTGGTGTCTTTCTCCTGACGACTTGGTATGTCTCATGGATACTCTTCAAA
ATCTATGCCACAGAGGCTCATGTGTTTCCTGTTCAACCACCATTTGCAGAAGGGTCAGATGAGTGCCTTCCAAAAGTGTTAAATAGCAAT
CCTCCCCCCATCATAAAGTATTTAGCCTTGCAGGACCTGATGTTGCTTTCTCAATATTCTCCTTCACGAAGACAAGAAGTTTTCAGCCTC
AGCCAACCAGGTGGACATCCCCACAATTGGACAGCCATTTCAAGGGAGTGTTTGAATCTTTTAAATGGTATGACTCAGAAACTGATTCTC
TATCAAGAAGCTGCTGCTACGAATGGGAGAGTGTCTTCATCTTACCCAGTGGAACCTAAGAAATTAAATTCTCCAGAAGAAACTGCTTTT
CAGACACCAAAATCTAGCCAGATGCCTCGGCCTTCAGTGCCACCATTAGTTAAAACATCACTGTTTTCTTCAAAATTATCTACACCTGAT
GTTGTGAGCCCATTTGGGACCCCATTTGGCTCTAGTGTAATGAATCGGATGGCTGGAATTTTTGATGTAAACACCTGCTATGGGTCACCG
CAAAGTCCTCAGCTAATAAGAAGGGGGCCAAGATTGTGGACATCAGCTTCTGATCAGCAAATGACTGAATTTTCTAATCCTTCTCCATCT
ACCTCTATTAGTGCTGAGGCACCCAGAGGCCTCCATTCAGGCTGTTTTTTCAGATGCCCAAATGCATATTTGGGCATTAGAAGGTCTGTC
GCACTTAGTAGCAGCATCATTTACAGAGGATAGATTTGGAGTTGTCCAGACGACACTACCAGCTATCCTTAATACTTTGTTGACACTGCA
AGAGGCAGTCGACAAGTACTTTAAGCTTCCTCATGCTTCCAGTAAACCACCCCGGATTTCAGGAAGCCTTGTGGACACTTCATATAAAAC
ATTAAGATTTGCATTCAGAGCATCACTGAAAACTGCCATCTATCGAATAACTACTACATTTGGTGAACATCTGAATGCTGTGCAAGCATC
TGCAGAACATCAGAAAAGACTTCAACAGTTCTTGGAGTTCAAAGAATAGTTAAGTAATATAAACTGTGTTCATTACACTGCTGATACAAC
TACAGATGGGACAGTAAATGTTCAGCATTCTTGGATCAGAAGAAAACGGACTAATTAGATGCTTCCTTTGTCGTGGTGGTTGCTTTGAAA
ACTATACTTTAATGGGAGAAATCATGGAAAGAAATTCTCAACAGAATAACTGAAAACTGCCTTTTCTGTACCGATTGCTTTTTGTGTGTG
TGGTATAATAAAATCTTTATTCAATTTTACAGAAGCATTGATGGCAGTCGAAATGTCTCTAGCTCATATAACTTAATAGTAATAACTAAA
AAACTTTTAGAATTTACTTTTGAAAGGAGGGAAGCCAGTTCTGAAATGAGTATAGGTTGATTTCATAGTCTTCTTAATTAAGAGTTTAGC
TCTTTGTAAACTCAAAATACATAAACTTTTTAAGTGTAGTTTCATTTACTGAAGGATAAAAATGGTAACAGTGCAGCAATATTCACAAAA
AATATTGTCTAACGGACATATTTTGTTAATCTGTTAGGTTGGGTTTTTGTTTCCAGGGACAAATTAAATTTGTATGATTACCCAAAAAAG
GGTCTCAGTTTACAGATGCTAACTCTATATAAAGGAATGTGGAAAAACTCAGTTCTTAAGTTACAAGATTAAAAATTCACATTTGGTCTT
TAAGAAACAATTGACTGACATCTATGAATTTATTTTGTATCATGCTAGTAAACACGAAGTATTAATGTATGGGTATTTTCCCAGCTAGTT
TTGCTTTCTTTTTCTGGAGCAAAACATTAAGTGATTGCAGAGTTTTTCAAGCAAGAGAAAAAGGTTTGCAAAAAAACCCAGGAAATGTTC
CCTTTTTTCCCCACCATTCATCTTCATTAGATCAAATTCTGTGAAACTTGTCTGGTCTCTCAAAGGGAGCAGCCTCTGTAGTGTTAAATG
GCTAATTAAAATAGGAAGATCTTTATAGCCAGAAACAACTTAGTCATCAAATAGCAAGTGAAACCAAAACGTCAGAGGGATTACTGTACT
TGGAAGTATGTTGTGTGTCCCAAATGTGAACGAAGTATTGTTAGAATTTATTAGATCAGCTTCTTTGGAGATCAAAGATTGGAAATCCTA
GTCATAGATATTCACTGGACTGGCTTTGGACTGAAATGCTCCTTTGTAATTCTTTTCCTATTGTCTTTTCCTTCTAGTGTCCCAAAATAT
TTTCTTTAAAGTCAGCACAGTACTGTATATGAATCTTTAATGTGGTATCATATATGTCTACTTTTGTCTGATTCATCGATGTATTATATC
TTTATAATTGAATATTTTAGCTCCGGGTCCTGTTGCCCCTTCAAGCAGTACATGCCAAATTATAAATAGGTGCTACTGGCCTTGAGCATA
TCACTGTGGGACAGTTCCCCAATTGTCAAGTGTTTAGATATGTAGACTATTGCCATTTGTTTTTTTGTTTTGGTTTTGCTTTGTGTCTGA
AGCTGAATTGATTTCTTTTTTTTGAATGTGAAAGTTGAATTTCAAACGTAGTCATTTCTTACAGATGGCCAAGACAGAAAATTGTGGCTA
GGTTGACTGAGAACTGTTGTCTTCCATGTATTAACACAATTAAGCTTTTTATATTCCACTCTCTGTGCTGACCCTGGCTGAGGCATTTTG
GGAGACAAGGACTCTGAATCTTCTGCTTCCATTAAAGAAGAACTGTGATATTCAACATTGGATTTCTGAGAATAAAGATAGGATGATTCC
TTTGAACTTTGACTTACTTGTATAAAATGTCCAGCTAGGTTAGGTTTTTGCCATTTCCTATATACTTTGGGTAAAGCTACATTTGATGAG
CAATGTGAATGTTTCTGAGAATGTTCATTCCTGTTTTCTCTTAAGAGAATGTGCTGTGTACTAAATACAGGCCACATAGTGTCTGCCTGT
TGAAGATCTGGAAACTGCCTCCCCAGATCTGTATTGTATTTGGTAGGTAAGGGGGTCAGTTTCTTTTTCTCATTGTGTGTTGATAATCTA
CACACCATCTGTTGGAACCAGGGTGTTATTATGGGGAACTCCTCCTGTGTACTAGGAGGAGGACCTTAGGGAGACCAAGAGGAGAGAAGC
ATTTCCTTTGATGAAGTCACATCCTGTCTATGAGCCCACTAATGCTGTAACATTGGCCTGAAAGAGAGTGTTCTTTAAAAGCCTTTCTCG
GCTGTTAGTATAAAAACATGATGGTATCAGCTCTTAGCATGTTTGCTTGACCCTTATGGAAGGTATAAATCCACAGAACTTCCTTCCCAG
AGAACTGGGAAATTGTCCTAGAAATAAACCTTGTACAGTTGAGTGGACATGGATAAGCAACAATTTGTTACTTTGCAGGATTTGTTCCTT
GGTAATTGTTTGGTGTGTCATCCTGTAAATATTCATGATAGTCTGTTTATATCCTTTTGTATATCGTTGATACTGGATTGGGTAGAAAAA

>3243_3243_8_AK4-NDC1_AK4_chr1_65656512_ENST00000546702_NDC1_chr1_54293846_ENST00000540001_length(amino acids)=516AA_BP=67
MLLVARRGARARRAPHGRGAHPPTPGGEVGEMAKQYIEKSLLVPDHVITRLMMSELENRRGQHWLLDVVPSIPCSRLALIGKIIHPQQLM
HSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQTCLNEYHLFFLLTGAFMGYSYSLLYFVNNMNYLPFPIIQQYKFLRFR
RSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKAWISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYAT
EAHVFPVQPPFAEGSDECLPKVLNSNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLNLLNGMTQKLILYQEA
AATNGRVSSSYPVEPKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AK4-NDC1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AK4-NDC1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AK4-NDC1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource