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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AKAP13-RET (FusionGDB2 ID:3313)

Fusion Gene Summary for AKAP13-RET

check button Fusion gene summary
Fusion gene informationFusion gene name: AKAP13-RET
Fusion gene ID: 3313
HgeneTgene
Gene symbol

AKAP13

RET

Gene ID

11214

5979

Gene nameA-kinase anchoring protein 13ret proto-oncogene
SynonymsAKAP-13|AKAP-Lbc|ARHGEF13|BRX|HA-3|Ht31|LBC|PRKA13|PROTO-LB|PROTO-LBC|c-lbc|p47CDHF12|CDHR16|HSCR1|MEN2A|MEN2B|MTC1|PTC|RET-ELE1
Cytomap

15q25.3

10q11.21

Type of geneprotein-codingprotein-coding
DescriptionA-kinase anchor protein 13A kinase (PRKA) anchor protein 13LBC oncogenebreast cancer nuclear receptor-binding auxiliary proteinguanine nucleotide exchange factor Lbchuman thyroid-anchoring protein 31lymphoid blast crisis oncogenenon-oncogenic Rho Gproto-oncogene tyrosine-protein kinase receptor RetRET receptor tyrosine kinasecadherin family member 12cadherin-related family member 16proto-oncogene c-Retrearranged during transfectionret proto-oncogene (multiple endocrine neoplasia and medullary
Modification date2020031320200322
UniProtAcc

Q12802

RTL1

Ensembl transtripts involved in fusion geneENST00000560579, ENST00000361243, 
ENST00000394510, ENST00000394518, 
ENST00000560302, 		ENST00000340058, 
ENST00000355710, 
Fusion gene scores* DoF score37 X 24 X 13=1154432 X 31 X 11=10912
# samples 4148
** MAII scorelog2(41/11544*10)=-4.81537548498575
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(48/10912*10)=-4.50673733341565
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AKAP13 [Title/Abstract] AND RET [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAKAP13(86284726)-RET(43612032), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAKAP13

GO:0007186

G protein-coupled receptor signaling pathway

11546812

HgeneAKAP13

GO:0035025

positive regulation of Rho protein signal transduction

11546812

TgeneRET

GO:0030155

regulation of cell adhesion

21357690

TgeneRET

GO:0030335

positive regulation of cell migration

20702524

TgeneRET

GO:0033619

membrane protein proteolysis

21357690

TgeneRET

GO:0033630

positive regulation of cell adhesion mediated by integrin

20702524

TgeneRET

GO:0035860

glial cell-derived neurotrophic factor receptor signaling pathway

28953886

TgeneRET

GO:0043410

positive regulation of MAPK cascade

28846099


check buttonFusion gene breakpoints across AKAP13 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RET (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-FK-A3SG-01AAKAP13chr15

86284726

-RETchr10

43612032

+
ChimerDB4THCATCGA-FK-A3SG-01AAKAP13chr15

86284726

+RETchr10

43612032

+
ChimerDB4THCATCGA-FK-A3SGAKAP13chr15

86284726

+RETchr10

43612031

+


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Fusion Gene ORF analysis for AKAP13-RET

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000560579ENST00000340058AKAP13chr15

86284726

+RETchr10

43612032

+
3UTR-3CDSENST00000560579ENST00000340058AKAP13chr15

86284726

+RETchr10

43612031

+
3UTR-3CDSENST00000560579ENST00000355710AKAP13chr15

86284726

+RETchr10

43612032

+
3UTR-3CDSENST00000560579ENST00000355710AKAP13chr15

86284726

+RETchr10

43612031

+
In-frameENST00000361243ENST00000340058AKAP13chr15

86284726

+RETchr10

43612032

+
In-frameENST00000361243ENST00000340058AKAP13chr15

86284726

+RETchr10

43612031

+
In-frameENST00000361243ENST00000355710AKAP13chr15

86284726

+RETchr10

43612032

+
In-frameENST00000361243ENST00000355710AKAP13chr15

86284726

+RETchr10

43612031

+
In-frameENST00000394510ENST00000340058AKAP13chr15

86284726

+RETchr10

43612032

+
In-frameENST00000394510ENST00000340058AKAP13chr15

86284726

+RETchr10

43612031

+
In-frameENST00000394510ENST00000355710AKAP13chr15

86284726

+RETchr10

43612032

+
In-frameENST00000394510ENST00000355710AKAP13chr15

86284726

+RETchr10

43612031

+
In-frameENST00000394518ENST00000340058AKAP13chr15

86284726

+RETchr10

43612032

+
In-frameENST00000394518ENST00000340058AKAP13chr15

86284726

+RETchr10

43612031

+
In-frameENST00000394518ENST00000355710AKAP13chr15

86284726

+RETchr10

43612032

+
In-frameENST00000394518ENST00000355710AKAP13chr15

86284726

+RETchr10

43612031

+
intron-3CDSENST00000560302ENST00000340058AKAP13chr15

86284726

+RETchr10

43612032

+
intron-3CDSENST00000560302ENST00000340058AKAP13chr15

86284726

+RETchr10

43612031

+
intron-3CDSENST00000560302ENST00000355710AKAP13chr15

86284726

+RETchr10

43612032

+
intron-3CDSENST00000560302ENST00000355710AKAP13chr15

86284726

+RETchr10

43612031

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394518AKAP13chr1586284726+ENST00000355710RETchr1043612032+1144481539593613088
ENST00000394518AKAP13chr1586284726+ENST00000340058RETchr1043612032+998681539592353046
ENST00000361243AKAP13chr1586284726+ENST00000355710RETchr1043612032+1144281518193593092
ENST00000361243AKAP13chr1586284726+ENST00000340058RETchr1043612032+998481518192333050
ENST00000394510AKAP13chr1586284726+ENST00000355710RETchr1043612032+631030195542271390
ENST00000394510AKAP13chr1586284726+ENST00000340058RETchr1043612032+485230195541011348
ENST00000394518AKAP13chr1586284726+ENST00000355710RETchr1043612031+1144481539593613088
ENST00000394518AKAP13chr1586284726+ENST00000340058RETchr1043612031+998681539592353046
ENST00000361243AKAP13chr1586284726+ENST00000355710RETchr1043612031+1144281518193593092
ENST00000361243AKAP13chr1586284726+ENST00000340058RETchr1043612031+998481518192333050
ENST00000394510AKAP13chr1586284726+ENST00000355710RETchr1043612031+631030195542271390
ENST00000394510AKAP13chr1586284726+ENST00000340058RETchr1043612031+485230195541011348

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394518ENST00000355710AKAP13chr1586284726+RETchr1043612032+0.0011846390.9988154
ENST00000394518ENST00000340058AKAP13chr1586284726+RETchr1043612032+0.0008318940.99916816
ENST00000361243ENST00000355710AKAP13chr1586284726+RETchr1043612032+0.0011545920.99884534
ENST00000361243ENST00000340058AKAP13chr1586284726+RETchr1043612032+0.00080410.9991959
ENST00000394510ENST00000355710AKAP13chr1586284726+RETchr1043612032+0.0008696380.9991304
ENST00000394510ENST00000340058AKAP13chr1586284726+RETchr1043612032+0.0009498990.9990501
ENST00000394518ENST00000355710AKAP13chr1586284726+RETchr1043612031+0.0011846390.9988154
ENST00000394518ENST00000340058AKAP13chr1586284726+RETchr1043612031+0.0008318940.99916816
ENST00000361243ENST00000355710AKAP13chr1586284726+RETchr1043612031+0.0011545920.99884534
ENST00000361243ENST00000340058AKAP13chr1586284726+RETchr1043612031+0.00080410.9991959
ENST00000394510ENST00000355710AKAP13chr1586284726+RETchr1043612031+0.0008696380.9991304
ENST00000394510ENST00000340058AKAP13chr1586284726+RETchr1043612031+0.0009498990.9990501

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Fusion Genomic Features for AKAP13-RET


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AKAP13chr1586284726+RETchr1043612031+6.48E-070.9999994
AKAP13chr1586284726+RETchr1043612031+6.48E-070.9999994
AKAP13chr1586284726+RETchr1043612031+6.48E-070.9999994
AKAP13chr1586284726+RETchr1043612031+6.48E-070.9999994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for AKAP13-RET


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:86284726/chr10:43612032)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AKAP13

Q12802

RET

RTL1

FUNCTION: Scaffold protein that plays an important role in assembling signaling complexes downstream of several types of G protein-coupled receptors. Activates RHOA in response to signaling via G protein-coupled receptors via its function as Rho guanine nucleotide exchange factor (PubMed:11546812, PubMed:15229649, PubMed:23090968, PubMed:25186459, PubMed:24993829). May also activate other Rho family members (PubMed:11546812). Part of a kinase signaling complex that links ADRA1A and ADRA1B adrenergic receptor signaling to the activation of downstream p38 MAP kinases, such as MAPK11 and MAPK14 (PubMed:17537920, PubMed:23716597, PubMed:21224381). Part of a signaling complex that links ADRA1B signaling to the activation of RHOA and IKBKB/IKKB, leading to increased NF-kappa-B transcriptional activity (PubMed:23090968). Part of a RHOA-dependent signaling cascade that mediates responses to lysophosphatidic acid (LPA), a signaling molecule that activates G-protein coupled receptors and potentiates transcriptional activation of the glucocorticoid receptor NR3C1 (PubMed:16469733). Part of a signaling cascade that stimulates MEF2C-dependent gene expression in response to lysophosphatidic acid (LPA) (By similarity). Part of a signaling pathway that activates MAPK11 and/or MAPK14 and leads to increased transcription activation of the estrogen receptors ESR1 and ESR2 (PubMed:9627117, PubMed:11579095). Part of a signaling cascade that links cAMP and EGFR signaling to BRAF signaling and to PKA-mediated phosphorylation of KSR1, leading to the activation of downstream MAP kinases, such as MAPK1 or MAPK3 (PubMed:21102438). Functions as scaffold protein that anchors cAMP-dependent protein kinase (PKA) and PRKD1. This promotes activation of PRKD1, leading to increased phosphorylation of HDAC5 and ultimately cardiomyocyte hypertrophy (By similarity). Has no guanine nucleotide exchange activity on CDC42, Ras or Rac (PubMed:11546812). Required for normal embryonic heart development, and in particular for normal sarcomere formation in the developing cardiomyocytes (By similarity). Plays a role in cardiomyocyte growth and cardiac hypertrophy in response to activation of the beta-adrenergic receptor by phenylephrine or isoproterenol (PubMed:17537920, PubMed:23090968). Required for normal adaptive cardiac hypertrophy in response to pressure overload (PubMed:23716597). Plays a role in osteogenesis (By similarity). {ECO:0000250|UniProtKB:E9Q394, ECO:0000269|PubMed:11546812, ECO:0000269|PubMed:11579095, ECO:0000269|PubMed:17537920, ECO:0000269|PubMed:21224381, ECO:0000269|PubMed:23716597, ECO:0000269|PubMed:24993829, ECO:0000269|PubMed:25186459, ECO:0000269|PubMed:9627117, ECO:0000269|PubMed:9891067}.1358

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35371758_179026902818.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35372345_238126902818.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35372568_268326902818.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35371758_179026862814.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35372345_238126862814.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35372568_268326862814.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35371758_179026902818.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35372345_238126902818.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35372568_268326902818.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35371758_179026862814.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35372345_238126862814.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35372568_268326862814.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35371471_147426902818.0Compositional biasNote=Poly-Ser
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35371534_153726902818.0Compositional biasNote=Poly-Glu
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35371471_147426862814.0Compositional biasNote=Poly-Ser
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35371534_153726862814.0Compositional biasNote=Poly-Glu
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35371471_147426902818.0Compositional biasNote=Poly-Ser
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35371534_153726902818.0Compositional biasNote=Poly-Glu
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35371471_147426862814.0Compositional biasNote=Poly-Ser
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35371534_153726862814.0Compositional biasNote=Poly-Glu
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35371994_219126902818.0DomainDH
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35372231_233326902818.0DomainPH
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35371994_219126862814.0DomainDH
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35372231_233326862814.0DomainPH
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35371994_219126902818.0DomainDH
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35372231_233326902818.0DomainPH
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35371994_219126862814.0DomainDH
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35372231_233326862814.0DomainPH
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35371791_183826902818.0Zinc fingerPhorbol-ester/DAG-type
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35371791_183826862814.0Zinc fingerPhorbol-ester/DAG-type
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35371791_183826902818.0Zinc fingerPhorbol-ester/DAG-type
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35371791_183826862814.0Zinc fingerPhorbol-ester/DAG-type
TgeneRETchr15:86284726chr10:43612031ENST000003400581019724_10167121073.0DomainProtein kinase
TgeneRETchr15:86284726chr10:43612031ENST000003557101020724_10167121115.0DomainProtein kinase
TgeneRETchr15:86284726chr10:43612032ENST000003400581019724_10167121073.0DomainProtein kinase
TgeneRETchr15:86284726chr10:43612032ENST000003557101020724_10167121115.0DomainProtein kinase
TgeneRETchr15:86284726chr10:43612031ENST000003400581019730_7387121073.0Nucleotide bindingATP
TgeneRETchr15:86284726chr10:43612031ENST000003557101020730_7387121115.0Nucleotide bindingATP
TgeneRETchr15:86284726chr10:43612032ENST000003400581019730_7387121073.0Nucleotide bindingATP
TgeneRETchr15:86284726chr10:43612032ENST000003557101020730_7387121115.0Nucleotide bindingATP
TgeneRETchr15:86284726chr10:43612031ENST000003400581019805_8077121073.0RegionNote=Inhibitors binding
TgeneRETchr15:86284726chr10:43612031ENST000003557101020805_8077121115.0RegionNote=Inhibitors binding
TgeneRETchr15:86284726chr10:43612032ENST000003400581019805_8077121073.0RegionNote=Inhibitors binding
TgeneRETchr15:86284726chr10:43612032ENST000003557101020805_8077121115.0RegionNote=Inhibitors binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+141758_17900180.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+142345_23810180.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+142568_26830180.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+141758_17900180.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+142345_23810180.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+142568_26830180.0Coiled coilOntology_term=ECO:0000255
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35372778_279026902818.0Compositional biasNote=Poly-Lys
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35372778_279026862814.0Compositional biasNote=Poly-Lys
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+141471_14740180.0Compositional biasNote=Poly-Ser
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+141534_15370180.0Compositional biasNote=Poly-Glu
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+142778_27900180.0Compositional biasNote=Poly-Lys
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35372778_279026902818.0Compositional biasNote=Poly-Lys
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35372778_279026862814.0Compositional biasNote=Poly-Lys
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+141471_14740180.0Compositional biasNote=Poly-Ser
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+141534_15370180.0Compositional biasNote=Poly-Glu
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+142778_27900180.0Compositional biasNote=Poly-Lys
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+141994_21910180.0DomainDH
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+142231_23330180.0DomainPH
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+141994_21910180.0DomainDH
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+142231_23330180.0DomainPH
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+141791_18380180.0Zinc fingerPhorbol-ester/DAG-type
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+141791_18380180.0Zinc fingerPhorbol-ester/DAG-type
TgeneRETchr15:86284726chr10:43612031ENST000003400581019168_2727121073.0DomainCadherin
TgeneRETchr15:86284726chr10:43612031ENST000003557101020168_2727121115.0DomainCadherin
TgeneRETchr15:86284726chr10:43612032ENST000003400581019168_2727121073.0DomainCadherin
TgeneRETchr15:86284726chr10:43612032ENST000003557101020168_2727121115.0DomainCadherin
TgeneRETchr15:86284726chr10:43612031ENST00000340058101929_6357121073.0Topological domainExtracellular
TgeneRETchr15:86284726chr10:43612031ENST000003400581019658_11147121073.0Topological domainCytoplasmic
TgeneRETchr15:86284726chr10:43612031ENST00000355710102029_6357121115.0Topological domainExtracellular
TgeneRETchr15:86284726chr10:43612031ENST000003557101020658_11147121115.0Topological domainCytoplasmic
TgeneRETchr15:86284726chr10:43612032ENST00000340058101929_6357121073.0Topological domainExtracellular
TgeneRETchr15:86284726chr10:43612032ENST000003400581019658_11147121073.0Topological domainCytoplasmic
TgeneRETchr15:86284726chr10:43612032ENST00000355710102029_6357121115.0Topological domainExtracellular
TgeneRETchr15:86284726chr10:43612032ENST000003557101020658_11147121115.0Topological domainCytoplasmic
TgeneRETchr15:86284726chr10:43612031ENST000003400581019636_6577121073.0TransmembraneHelical
TgeneRETchr15:86284726chr10:43612031ENST000003557101020636_6577121115.0TransmembraneHelical
TgeneRETchr15:86284726chr10:43612032ENST000003400581019636_6577121073.0TransmembraneHelical
TgeneRETchr15:86284726chr10:43612032ENST000003557101020636_6577121115.0TransmembraneHelical


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Fusion Gene Sequence for AKAP13-RET


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>3313_3313_1_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612031_ENST00000340058_length(transcript)=9984nt_BP=8151nt
TGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCTGGGTCATGAAACTT
AATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATGATGTAGTGTTTTAC
TTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTGCTCCTGGTCATGAT
TGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACTTTCATTTCGTCCAG
GATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTCTTGACCAGTCAGGA
CCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGTGGAATGTATTGGGG
ACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGTTGACGTGGTTCCTG
TTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGGAGCGAGGCTATCAC
AAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGTATGGAGACTGTTCT
GTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTGGAGACGGTTGCACT
GGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGCCCTTAATGATGACA
GCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGCGACTTTCTTCTTCT
GAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCATAGTTGAGGAGGAG
AATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTGTGGACTCTGGAACT
GTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTGGAAACAGAAATGAA
GAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAGACTTGGTCATGGAG
CCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTGCAGGGGAAATGGAA
CATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTGAGAACTCTAATATT
GGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTGCTGCCAGTTCCCTG
GATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGGAAACTTCACGAAGT
CGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAGATGGATTAGAACCT
TATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATGTAATGCCACACCAG
AACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACGATAAACTTTGTGCA
GACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCGAGTCCGAAAGCACC
ACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCTCTGACCCTGTAAGG
GATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAGATAAACCTTTAACA
AATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAGTAATATCAGACAGT
ACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGAAAGAAAAGGGAACA
GCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGCCACTAGAAGACAGG
GCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTGGTGGAGAGCATGAG
GGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTAAGGCCACTTTGGCT
TTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGGATAAAGCGGTGACC
TGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAGATACTCAACAATTT
CATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTGCCTTTCTTAAGGCA
GAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGCCACCAGGAGCAAGT
CTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAGATGGGTCTGATGGG
TCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTAGTGCCTGTGAGGTG
AGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATATCACACAACACCCAA
GACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACAAAGCTGTGACTGAC
CCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCTGTACCATGGGTGAC
GCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACATGGAGCTCTCAGCC
CATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCTCTCTACCTTGCATG
GTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTGTCATCGAACAAGTC
AAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCACTAAAGGACTAGAG
AGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCACGGGGAGCCTTGCA
GGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGCCAGACGTGAAAGCT
GAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGATGAAGCAAGGCCCA
ATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCAAGCAGAGCCCAGAA
TGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGAGTGATTCTGACCTC
TTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCACCGGATCCAGTTCA
TCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGCCAAACAGGTCAAGA
GATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTGACCCAGGCGACGTG
GAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTTCTCCCTTCCGGAGG
CACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTATGAGCTGGTGCCCCTCTGGTGTGCAGTACTCT
GCTGGCCTGAGTGCTGACTTTAATTACAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCATCT
CTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAGAG
GATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACATCA
GCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCTTC
CACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGG
AAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAA
GATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTT
GTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAA
GGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCC
ACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATA
TTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATG
TCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAG
GGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATA
ATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCAT
GTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTC
CCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAA
AAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAG
TTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATG
AGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGA
ATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGAC
AGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGT
CAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAG
GTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACA
GTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAG
ATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAA
GATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGAC
CAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCA
ACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAG
ATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTT
TCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGAT
GGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAG
CAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAG
AAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAG
CAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAG
AGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAG
CTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGC
CGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTT
CTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTG
GCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCA
CATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTC
CTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCC
CTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTG
GCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTAC
GTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGG
TCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAG
ACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGG
CCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGAC
TCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACA
TGGATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGT
GATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTT
ACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAG
GAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTC
TACTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCA
CAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGC
CCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCA
CATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCT

>3313_3313_1_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612031_ENST00000340058_length(amino acids)=3050AA_BP=2690
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSMSWCPSGVQYSAGLSADFNYRSFSLEGLTGGAGVGNKP
SSSLEVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFH
STFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSS
IPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETAT
TPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESW
SRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVD
KSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVL
FQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGR
LKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLN
RDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAIN
EVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKR
NSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWE
ARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRK
NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSL
RGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEE
DSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEP

--------------------------------------------------------------
>3313_3313_2_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612031_ENST00000355710_length(transcript)=11442nt_BP=8151nt
TGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCTGGGTCATGAAACTT
AATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATGATGTAGTGTTTTAC
TTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTGCTCCTGGTCATGAT
TGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACTTTCATTTCGTCCAG
GATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTCTTGACCAGTCAGGA
CCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGTGGAATGTATTGGGG
ACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGTTGACGTGGTTCCTG
TTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGGAGCGAGGCTATCAC
AAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGTATGGAGACTGTTCT
GTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTGGAGACGGTTGCACT
GGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGCCCTTAATGATGACA
GCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGCGACTTTCTTCTTCT
GAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCATAGTTGAGGAGGAG
AATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTGTGGACTCTGGAACT
GTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTGGAAACAGAAATGAA
GAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAGACTTGGTCATGGAG
CCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTGCAGGGGAAATGGAA
CATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTGAGAACTCTAATATT
GGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTGCTGCCAGTTCCCTG
GATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGGAAACTTCACGAAGT
CGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAGATGGATTAGAACCT
TATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATGTAATGCCACACCAG
AACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACGATAAACTTTGTGCA
GACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCGAGTCCGAAAGCACC
ACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCTCTGACCCTGTAAGG
GATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAGATAAACCTTTAACA
AATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAGTAATATCAGACAGT
ACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGAAAGAAAAGGGAACA
GCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGCCACTAGAAGACAGG
GCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTGGTGGAGAGCATGAG
GGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTAAGGCCACTTTGGCT
TTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGGATAAAGCGGTGACC
TGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAGATACTCAACAATTT
CATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTGCCTTTCTTAAGGCA
GAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGCCACCAGGAGCAAGT
CTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAGATGGGTCTGATGGG
TCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTAGTGCCTGTGAGGTG
AGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATATCACACAACACCCAA
GACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACAAAGCTGTGACTGAC
CCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCTGTACCATGGGTGAC
GCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACATGGAGCTCTCAGCC
CATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCTCTCTACCTTGCATG
GTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTGTCATCGAACAAGTC
AAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCACTAAAGGACTAGAG
AGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCACGGGGAGCCTTGCA
GGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGCCAGACGTGAAAGCT
GAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGATGAAGCAAGGCCCA
ATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCAAGCAGAGCCCAGAA
TGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGAGTGATTCTGACCTC
TTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCACCGGATCCAGTTCA
TCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGCCAAACAGGTCAAGA
GATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTGACCCAGGCGACGTG
GAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTTCTCCCTTCCGGAGG
CACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTATGAGCTGGTGCCCCTCTGGTGTGCAGTACTCT
GCTGGCCTGAGTGCTGACTTTAATTACAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCATCT
CTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAGAG
GATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACATCA
GCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCTTC
CACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGG
AAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAA
GATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTT
GTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAA
GGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCC
ACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATA
TTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATG
TCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAG
GGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATA
ATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCAT
GTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTC
CCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAA
AAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAG
TTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATG
AGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGA
ATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGAC
AGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGT
CAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAG
GTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACA
GTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAG
ATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAA
GATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGAC
CAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCA
ACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAG
ATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTT
TCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGAT
GGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAG
CAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAG
AAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAG
CAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAG
AGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAG
CTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGC
CGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTT
CTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTG
GCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCA
CATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTC
CTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCC
CTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTG
GCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTAC
GTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGG
TCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAG
ACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGG
CCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGAC
TCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACA
TGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACT
GGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAA
CATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACAT
TGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTG
ATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACC
CAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGAC
CTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATG
CTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAA
GAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATT
TGGTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGA
AGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACA
GTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCAC
ACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATC
AACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTG
ATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTAC
AAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACT
CCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGA
TTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTC
ACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAG
GGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATA
TCTATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATT
AAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGAT
GGGGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTAC
TGGAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTA
AAATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCA

>3313_3313_2_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612031_ENST00000355710_length(amino acids)=3092AA_BP=2690
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSMSWCPSGVQYSAGLSADFNYRSFSLEGLTGGAGVGNKP
SSSLEVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFH
STFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSS
IPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETAT
TPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESW
SRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVD
KSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVL
FQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGR
LKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLN
RDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAIN
EVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKR
NSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWE
ARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRK
NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSL
RGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEE
DSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEP
DKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADG

--------------------------------------------------------------
>3313_3313_3_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612032_ENST00000340058_length(transcript)=9984nt_BP=8151nt
TGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCTGGGTCATGAAACTT
AATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATGATGTAGTGTTTTAC
TTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTGCTCCTGGTCATGAT
TGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACTTTCATTTCGTCCAG
GATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTCTTGACCAGTCAGGA
CCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGTGGAATGTATTGGGG
ACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGTTGACGTGGTTCCTG
TTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGGAGCGAGGCTATCAC
AAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGTATGGAGACTGTTCT
GTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTGGAGACGGTTGCACT
GGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGCCCTTAATGATGACA
GCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGCGACTTTCTTCTTCT
GAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCATAGTTGAGGAGGAG
AATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTGTGGACTCTGGAACT
GTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTGGAAACAGAAATGAA
GAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAGACTTGGTCATGGAG
CCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTGCAGGGGAAATGGAA
CATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTGAGAACTCTAATATT
GGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTGCTGCCAGTTCCCTG
GATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGGAAACTTCACGAAGT
CGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAGATGGATTAGAACCT
TATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATGTAATGCCACACCAG
AACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACGATAAACTTTGTGCA
GACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCGAGTCCGAAAGCACC
ACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCTCTGACCCTGTAAGG
GATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAGATAAACCTTTAACA
AATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAGTAATATCAGACAGT
ACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGAAAGAAAAGGGAACA
GCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGCCACTAGAAGACAGG
GCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTGGTGGAGAGCATGAG
GGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTAAGGCCACTTTGGCT
TTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGGATAAAGCGGTGACC
TGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAGATACTCAACAATTT
CATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTGCCTTTCTTAAGGCA
GAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGCCACCAGGAGCAAGT
CTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAGATGGGTCTGATGGG
TCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTAGTGCCTGTGAGGTG
AGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATATCACACAACACCCAA
GACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACAAAGCTGTGACTGAC
CCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCTGTACCATGGGTGAC
GCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACATGGAGCTCTCAGCC
CATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCTCTCTACCTTGCATG
GTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTGTCATCGAACAAGTC
AAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCACTAAAGGACTAGAG
AGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCACGGGGAGCCTTGCA
GGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGCCAGACGTGAAAGCT
GAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGATGAAGCAAGGCCCA
ATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCAAGCAGAGCCCAGAA
TGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGAGTGATTCTGACCTC
TTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCACCGGATCCAGTTCA
TCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGCCAAACAGGTCAAGA
GATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTGACCCAGGCGACGTG
GAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTTCTCCCTTCCGGAGG
CACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTATGAGCTGGTGCCCCTCTGGTGTGCAGTACTCT
GCTGGCCTGAGTGCTGACTTTAATTACAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCATCT
CTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAGAG
GATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACATCA
GCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCTTC
CACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGG
AAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAA
GATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTT
GTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAA
GGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCC
ACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATA
TTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATG
TCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAG
GGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATA
ATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCAT
GTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTC
CCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAA
AAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAG
TTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATG
AGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGA
ATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGAC
AGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGT
CAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAG
GTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACA
GTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAG
ATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAA
GATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGAC
CAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCA
ACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAG
ATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTT
TCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGAT
GGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAG
CAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAG
AAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAG
CAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAG
AGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAG
CTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGC
CGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTT
CTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTG
GCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCA
CATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTC
CTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCC
CTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTG
GCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTAC
GTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGG
TCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAG
ACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGG
CCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGAC
TCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACA
TGGATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGT
GATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTT
ACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAG
GAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTC
TACTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCA
CAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGC
CCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCA
CATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCT

>3313_3313_3_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612032_ENST00000340058_length(amino acids)=3050AA_BP=2690
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSMSWCPSGVQYSAGLSADFNYRSFSLEGLTGGAGVGNKP
SSSLEVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFH
STFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSS
IPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETAT
TPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESW
SRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVD
KSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVL
FQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGR
LKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLN
RDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAIN
EVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKR
NSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWE
ARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRK
NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSL
RGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEE
DSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEP

--------------------------------------------------------------
>3313_3313_4_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612032_ENST00000355710_length(transcript)=11442nt_BP=8151nt
TGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCTGGGTCATGAAACTT
AATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATGATGTAGTGTTTTAC
TTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTGCTCCTGGTCATGAT
TGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACTTTCATTTCGTCCAG
GATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTCTTGACCAGTCAGGA
CCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGTGGAATGTATTGGGG
ACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGTTGACGTGGTTCCTG
TTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGGAGCGAGGCTATCAC
AAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGTATGGAGACTGTTCT
GTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTGGAGACGGTTGCACT
GGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGCCCTTAATGATGACA
GCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGCGACTTTCTTCTTCT
GAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCATAGTTGAGGAGGAG
AATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTGTGGACTCTGGAACT
GTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTGGAAACAGAAATGAA
GAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAGACTTGGTCATGGAG
CCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTGCAGGGGAAATGGAA
CATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTGAGAACTCTAATATT
GGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTGCTGCCAGTTCCCTG
GATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGGAAACTTCACGAAGT
CGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAGATGGATTAGAACCT
TATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATGTAATGCCACACCAG
AACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACGATAAACTTTGTGCA
GACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCGAGTCCGAAAGCACC
ACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCTCTGACCCTGTAAGG
GATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAGATAAACCTTTAACA
AATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAGTAATATCAGACAGT
ACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGAAAGAAAAGGGAACA
GCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGCCACTAGAAGACAGG
GCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTGGTGGAGAGCATGAG
GGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTAAGGCCACTTTGGCT
TTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGGATAAAGCGGTGACC
TGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAGATACTCAACAATTT
CATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTGCCTTTCTTAAGGCA
GAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGCCACCAGGAGCAAGT
CTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAGATGGGTCTGATGGG
TCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTAGTGCCTGTGAGGTG
AGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATATCACACAACACCCAA
GACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACAAAGCTGTGACTGAC
CCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCTGTACCATGGGTGAC
GCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACATGGAGCTCTCAGCC
CATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCTCTCTACCTTGCATG
GTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTGTCATCGAACAAGTC
AAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCACTAAAGGACTAGAG
AGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCACGGGGAGCCTTGCA
GGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGCCAGACGTGAAAGCT
GAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGATGAAGCAAGGCCCA
ATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCAAGCAGAGCCCAGAA
TGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGAGTGATTCTGACCTC
TTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCACCGGATCCAGTTCA
TCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGCCAAACAGGTCAAGA
GATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTGACCCAGGCGACGTG
GAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTTCTCCCTTCCGGAGG
CACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTATGAGCTGGTGCCCCTCTGGTGTGCAGTACTCT
GCTGGCCTGAGTGCTGACTTTAATTACAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCATCT
CTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAGAG
GATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACATCA
GCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCTTC
CACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGG
AAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAA
GATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTT
GTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAA
GGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCC
ACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATA
TTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATG
TCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAG
GGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATA
ATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCAT
GTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTC
CCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAA
AAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAG
TTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATG
AGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGA
ATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGAC
AGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGT
CAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAG
GTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACA
GTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAG
ATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAA
GATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGAC
CAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCA
ACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAG
ATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTT
TCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGAT
GGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAG
CAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAG
AAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAG
CAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAG
AGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAG
CTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGC
CGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTT
CTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTG
GCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCA
CATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTC
CTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCC
CTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTG
GCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTAC
GTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGG
TCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAG
ACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGG
CCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGAC
TCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACA
TGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACT
GGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAA
CATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACAT
TGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTG
ATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACC
CAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGAC
CTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATG
CTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAA
GAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATT
TGGTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGA
AGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACA
GTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCAC
ACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATC
AACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTG
ATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTAC
AAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACT
CCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGA
TTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTC
ACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAG
GGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATA
TCTATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATT
AAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGAT
GGGGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTAC
TGGAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTA
AAATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCA

>3313_3313_4_AKAP13-RET_AKAP13_chr15_86284726_ENST00000361243_RET_chr10_43612032_ENST00000355710_length(amino acids)=3092AA_BP=2690
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSMSWCPSGVQYSAGLSADFNYRSFSLEGLTGGAGVGNKP
SSSLEVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFH
STFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSS
IPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETAT
TPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESW
SRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVD
KSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVL
FQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGR
LKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLN
RDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAIN
EVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKR
NSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWE
ARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRK
NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSL
RGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEE
DSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEP
DKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADG

--------------------------------------------------------------
>3313_3313_5_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612031_ENST00000340058_length(transcript)=4852nt_BP=3019nt
GTCTAAAACTCTCTTTTCTCTTGGCTCTTCTTATTCGAGTGATGAGGAGGAGGAGTTGCATAATTCACGGCCCTTCCACAGTACCTTCCA
CAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGGAA
GAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAAGA
TAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTTGT
GGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAAGG
CTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCCAC
GGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATATT
TGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATGTC
AAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAGGG
AGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATAAT
AGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCATGT
CCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTCCC
CTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAAAA
GAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAGTT
TTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATGAG
CAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGAAT
ATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGACAG
CAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGTCA
GATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAGGT
TCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACAGT
GATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAGAT
GGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAAGA
TGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGACCA
AAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCAAC
ACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAGAT
CCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTTTC
CCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGATGG
CCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAGCA
GGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAGAA
ACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAGCA
GCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAGAG
GGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAGCT
CCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGCCG
GGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT
TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC
CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA
TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT
CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT
CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC
AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT
GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC
TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC
CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC
GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC
CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG
GATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGA
TGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTAC
ATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGA
AAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTA
CTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACA
GCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCC
CAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACA
TCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGT

>3313_3313_5_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612031_ENST00000340058_length(amino acids)=1348AA_BP=988
MHNSRPFHSTFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKT
VNGHTFSSIPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAV
LLVDETATTPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIES
KQLEAESWSRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILE
RKKESLVDKSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQ
RITKYPVLFQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSV
FLKNAAGRLKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQII
QDTINTLNRDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGG
PLMKSAINEVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNA
NLVFMLKRNSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEK
RRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQED
PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIV
EYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFG
LSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLM

--------------------------------------------------------------
>3313_3313_6_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612031_ENST00000355710_length(transcript)=6310nt_BP=3019nt
GTCTAAAACTCTCTTTTCTCTTGGCTCTTCTTATTCGAGTGATGAGGAGGAGGAGTTGCATAATTCACGGCCCTTCCACAGTACCTTCCA
CAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGGAA
GAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAAGA
TAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTTGT
GGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAAGG
CTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCCAC
GGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATATT
TGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATGTC
AAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAGGG
AGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATAAT
AGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCATGT
CCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTCCC
CTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAAAA
GAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAGTT
TTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATGAG
CAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGAAT
ATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGACAG
CAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGTCA
GATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAGGT
TCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACAGT
GATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAGAT
GGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAAGA
TGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGACCA
AAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCAAC
ACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAGAT
CCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTTTC
CCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGATGG
CCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAGCA
GGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAGAA
ACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAGCA
GCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAGAG
GGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAGCT
CCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGCCG
GGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT
TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC
CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA
TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT
CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT
CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC
AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT
GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC
TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC
CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC
GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC
CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG
GATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGG
GTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACA
TTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTG
GCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGAT
TTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCA
GTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCT
GAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCT
GGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGA
GGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTG
GTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAG
AGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGT
ATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACAC
CCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAA
CTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGAT
GTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAA
GATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCC
TCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATT
ACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCAC
AAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGG
AGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATC
TATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAA
AAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGG
GGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTG
GAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAA
ATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATG

>3313_3313_6_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612031_ENST00000355710_length(amino acids)=1390AA_BP=988
MHNSRPFHSTFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKT
VNGHTFSSIPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAV
LLVDETATTPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIES
KQLEAESWSRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILE
RKKESLVDKSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQ
RITKYPVLFQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSV
FLKNAAGRLKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQII
QDTINTLNRDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGG
PLMKSAINEVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNA
NLVFMLKRNSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEK
RRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQED
PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIV
EYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFG
LSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLM
LQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESP

--------------------------------------------------------------
>3313_3313_7_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612032_ENST00000340058_length(transcript)=4852nt_BP=3019nt
GTCTAAAACTCTCTTTTCTCTTGGCTCTTCTTATTCGAGTGATGAGGAGGAGGAGTTGCATAATTCACGGCCCTTCCACAGTACCTTCCA
CAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGGAA
GAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAAGA
TAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTTGT
GGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAAGG
CTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCCAC
GGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATATT
TGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATGTC
AAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAGGG
AGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATAAT
AGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCATGT
CCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTCCC
CTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAAAA
GAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAGTT
TTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATGAG
CAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGAAT
ATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGACAG
CAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGTCA
GATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAGGT
TCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACAGT
GATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAGAT
GGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAAGA
TGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGACCA
AAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCAAC
ACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAGAT
CCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTTTC
CCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGATGG
CCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAGCA
GGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAGAA
ACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAGCA
GCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAGAG
GGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAGCT
CCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGCCG
GGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT
TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC
CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA
TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT
CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT
CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC
AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT
GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC
TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC
CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC
GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC
CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG
GATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGA
TGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTAC
ATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGA
AAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTA
CTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACA
GCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCC
CAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACA
TCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGT

>3313_3313_7_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612032_ENST00000340058_length(amino acids)=1348AA_BP=988
MHNSRPFHSTFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKT
VNGHTFSSIPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAV
LLVDETATTPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIES
KQLEAESWSRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILE
RKKESLVDKSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQ
RITKYPVLFQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSV
FLKNAAGRLKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQII
QDTINTLNRDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGG
PLMKSAINEVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNA
NLVFMLKRNSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEK
RRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQED
PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIV
EYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFG
LSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLM

--------------------------------------------------------------
>3313_3313_8_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612032_ENST00000355710_length(transcript)=6310nt_BP=3019nt
GTCTAAAACTCTCTTTTCTCTTGGCTCTTCTTATTCGAGTGATGAGGAGGAGGAGTTGCATAATTCACGGCCCTTCCACAGTACCTTCCA
CAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGGAA
GAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAAGA
TAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTGTTGT
GGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACAAAGG
CTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCCAC
GGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATATT
TGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATGTC
AAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAGGG
AGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATAAT
AGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCATGT
CCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTCCC
CTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAAAA
GAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCAAGTT
TTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGATGAG
CAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGAAT
ATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGACAG
CAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGTCA
GATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAGGT
TCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACAGT
GATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAGAT
GGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAAGA
TGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGGACCA
AAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCCCAAC
ACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGGAGAT
CCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTTTC
CCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGATGG
CCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAGCA
GGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAGAA
ACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAGCA
GCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAGAG
GGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAGCT
CCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGCCG
GGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT
TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC
CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA
TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT
CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT
CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC
AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT
GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC
TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC
CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC
GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC
CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG
GATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGG
GTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACA
TTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTG
GCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGAT
TTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCA
GTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCT
GAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCT
GGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGA
GGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTG
GTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAG
AGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGT
ATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACAC
CCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAA
CTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGAT
GTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAA
GATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCC
TCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATT
ACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCAC
AAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGG
AGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATC
TATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAA
AAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGG
GGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTG
GAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAA
ATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATG

>3313_3313_8_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394510_RET_chr10_43612032_ENST00000355710_length(amino acids)=1390AA_BP=988
MHNSRPFHSTFHNTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKT
VNGHTFSSIPVVGPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAV
LLVDETATTPIFANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIES
KQLEAESWSRIIDSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILE
RKKESLVDKSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQ
RITKYPVLFQRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSV
FLKNAAGRLKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQII
QDTINTLNRDEDEGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGG
PLMKSAINEVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNA
NLVFMLKRNSEQVVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEK
RRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQED
PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIV
EYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFG
LSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLM
LQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESP

--------------------------------------------------------------
>3313_3313_9_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612031_ENST00000340058_length(transcript)=9986nt_BP=8153nt
GAGCGGCCGCCTATTGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCT
GGGTCATGAAACTTAATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATG
ATGTAGTGTTTTACTTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTG
CTCCTGGTCATGATTGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACT
TTCATTTCGTCCAGGATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTC
TTGACCAGTCAGGACCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGT
GGAATGTATTGGGGACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGT
TGACGTGGTTCCTGTTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGG
AGCGAGGCTATCACAAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGT
ATGGAGACTGTTCTGTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTG
GAGACGGTTGCACTGGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGC
CCTTAATGATGACAGCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGC
GACTTTCTTCTTCTGAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCA
TAGTTGAGGAGGAGAATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTG
TGGACTCTGGAACTGTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTG
GAAACAGAAATGAAGAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAG
ACTTGGTCATGGAGCCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTG
CAGGGGAAATGGAACATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTG
AGAACTCTAATATTGGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTG
CTGCCAGTTCCCTGGATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGG
AAACTTCACGAAGTCGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAG
ATGGATTAGAACCTTATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATG
TAATGCCACACCAGAACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACG
ATAAACTTTGTGCAGACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCG
AGTCCGAAAGCACCACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCT
CTGACCCTGTAAGGGATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAG
ATAAACCTTTAACAAATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAG
TAATATCAGACAGTACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGA
AAGAAAAGGGAACAGCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGC
CACTAGAAGACAGGGCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTG
GTGGAGAGCATGAGGGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTA
AGGCCACTTTGGCTTTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGG
ATAAAGCGGTGACCTGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAG
ATACTCAACAATTTCATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTG
CCTTTCTTAAGGCAGAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGC
CACCAGGAGCAAGTCTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAG
ATGGGTCTGATGGGTCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTA
GTGCCTGTGAGGTGAGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATAT
CACACAACACCCAAGACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACA
AAGCTGTGACTGACCCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCT
GTACCATGGGTGACGCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACA
TGGAGCTCTCAGCCCATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCT
CTCTACCTTGCATGGTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTG
TCATCGAACAAGTCAAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCA
CTAAAGGACTAGAGAGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCA
CGGGGAGCCTTGCAGGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGC
CAGACGTGAAAGCTGAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGA
TGAAGCAAGGCCCAATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCA
AGCAGAGCCCAGAATGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGA
GTGATTCTGACCTCTTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCA
CCGGATCCAGTTCATCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGC
CAAACAGGTCAAGAGATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTG
ACCCAGGCGACGTGGAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTT
CTCCCTTCCGGAGGCACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTTCAATGCGAGTTCTTGGGG
ATGTTGTCAGGAGACCTCCCATTCATAGGAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCAT
CTCTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAG
AGGATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACAT
CAGCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCT
TCCACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAAT
GGAAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAA
AAGATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTG
TTGTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACA
AAGGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGC
CCACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAA
TATTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACA
TGTCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATG
AGGGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGA
TAATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATC
ATGTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGT
TCCCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTG
AAAAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCA
AGTTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGA
TGAGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAA
GAATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAG
ACAGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTG
GTCAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAG
AGGTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAA
CAGTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAG
AGATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATG
AAGATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGG
ACCAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCC
CAACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGG
AGATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCG
TTTCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATG
ATGGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTG
AGCAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACC
AGAAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGA
AGCAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTG
AGAGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGG
AGCTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGC
GCCGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGG
TTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGG
TGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACC
CACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCT
TCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGG
CCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACT
TGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCT
ACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTAT
GGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGA
AGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAA
GGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTG
ACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCA
CATGGATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCT
GTGATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGT
TTACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAG
AGGAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACT
TCTACTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAG
CACAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCA
GCCCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTT
CACATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGT

>3313_3313_9_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612031_ENST00000340058_length(amino acids)=3046AA_BP=2686
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRPPIHRRSFSLEGLTGGAGVGNKPSSSL
EVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFHSTFH
NTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSSIPVV
GPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETATTPIF
ANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESWSRII
DSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVDKSEK
NFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRI
LQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGRLKEV
QAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLNRDED
EGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAINEVEI
LQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKRNSEQ
VVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEARER
ELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRKNLVL
GKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFL
RESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYV
KRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRP

--------------------------------------------------------------
>3313_3313_10_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612031_ENST00000355710_length(transcript)=11444nt_BP=8153nt
GAGCGGCCGCCTATTGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCT
GGGTCATGAAACTTAATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATG
ATGTAGTGTTTTACTTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTG
CTCCTGGTCATGATTGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACT
TTCATTTCGTCCAGGATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTC
TTGACCAGTCAGGACCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGT
GGAATGTATTGGGGACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGT
TGACGTGGTTCCTGTTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGG
AGCGAGGCTATCACAAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGT
ATGGAGACTGTTCTGTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTG
GAGACGGTTGCACTGGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGC
CCTTAATGATGACAGCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGC
GACTTTCTTCTTCTGAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCA
TAGTTGAGGAGGAGAATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTG
TGGACTCTGGAACTGTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTG
GAAACAGAAATGAAGAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAG
ACTTGGTCATGGAGCCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTG
CAGGGGAAATGGAACATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTG
AGAACTCTAATATTGGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTG
CTGCCAGTTCCCTGGATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGG
AAACTTCACGAAGTCGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAG
ATGGATTAGAACCTTATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATG
TAATGCCACACCAGAACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACG
ATAAACTTTGTGCAGACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCG
AGTCCGAAAGCACCACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCT
CTGACCCTGTAAGGGATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAG
ATAAACCTTTAACAAATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAG
TAATATCAGACAGTACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGA
AAGAAAAGGGAACAGCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGC
CACTAGAAGACAGGGCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTG
GTGGAGAGCATGAGGGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTA
AGGCCACTTTGGCTTTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGG
ATAAAGCGGTGACCTGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAG
ATACTCAACAATTTCATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTG
CCTTTCTTAAGGCAGAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGC
CACCAGGAGCAAGTCTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAG
ATGGGTCTGATGGGTCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTA
GTGCCTGTGAGGTGAGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATAT
CACACAACACCCAAGACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACA
AAGCTGTGACTGACCCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCT
GTACCATGGGTGACGCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACA
TGGAGCTCTCAGCCCATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCT
CTCTACCTTGCATGGTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTG
TCATCGAACAAGTCAAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCA
CTAAAGGACTAGAGAGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCA
CGGGGAGCCTTGCAGGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGC
CAGACGTGAAAGCTGAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGA
TGAAGCAAGGCCCAATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCA
AGCAGAGCCCAGAATGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGA
GTGATTCTGACCTCTTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCA
CCGGATCCAGTTCATCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGC
CAAACAGGTCAAGAGATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTG
ACCCAGGCGACGTGGAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTT
CTCCCTTCCGGAGGCACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTTCAATGCGAGTTCTTGGGG
ATGTTGTCAGGAGACCTCCCATTCATAGGAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCAT
CTCTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAG
AGGATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACAT
CAGCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCT
TCCACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAAT
GGAAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAA
AAGATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTG
TTGTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACA
AAGGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGC
CCACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAA
TATTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACA
TGTCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATG
AGGGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGA
TAATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATC
ATGTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGT
TCCCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTG
AAAAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCA
AGTTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGA
TGAGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAA
GAATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAG
ACAGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTG
GTCAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAG
AGGTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAA
CAGTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAG
AGATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATG
AAGATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGG
ACCAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCC
CAACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGG
AGATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCG
TTTCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATG
ATGGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTG
AGCAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACC
AGAAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGA
AGCAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTG
AGAGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGG
AGCTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGC
GCCGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGG
TTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGG
TGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACC
CACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCT
TCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGG
CCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACT
TGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCT
ACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTAT
GGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGA
AGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAA
GGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTG
ACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCA
CATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACA
CTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTT
AACATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCAC
ATTGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGG
TGATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCA
CCCAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGG
ACCTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAA
TGCTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGG
AAGAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACA
TTTGGTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGG
GAAGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAA
CAGTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGC
ACACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTA
TCAACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTC
TGATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCT
ACAAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACA
CTCCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCG
GATTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATT
TCACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAG
AGGGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAA
TATCTATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTA
TTAAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTG
ATGGGGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCT
ACTGGAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTG
TAAAATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAAT

>3313_3313_10_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612031_ENST00000355710_length(amino acids)=3088AA_BP=2686
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRPPIHRRSFSLEGLTGGAGVGNKPSSSL
EVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFHSTFH
NTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSSIPVV
GPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETATTPIF
ANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESWSRII
DSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVDKSEK
NFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRI
LQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGRLKEV
QAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLNRDED
EGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAINEVEI
LQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKRNSEQ
VVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEARER
ELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRKNLVL
GKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFL
RESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYV
KRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRP
VFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTG

--------------------------------------------------------------
>3313_3313_11_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612032_ENST00000340058_length(transcript)=9986nt_BP=8153nt
GAGCGGCCGCCTATTGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCT
GGGTCATGAAACTTAATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATG
ATGTAGTGTTTTACTTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTG
CTCCTGGTCATGATTGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACT
TTCATTTCGTCCAGGATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTC
TTGACCAGTCAGGACCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGT
GGAATGTATTGGGGACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGT
TGACGTGGTTCCTGTTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGG
AGCGAGGCTATCACAAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGT
ATGGAGACTGTTCTGTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTG
GAGACGGTTGCACTGGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGC
CCTTAATGATGACAGCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGC
GACTTTCTTCTTCTGAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCA
TAGTTGAGGAGGAGAATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTG
TGGACTCTGGAACTGTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTG
GAAACAGAAATGAAGAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAG
ACTTGGTCATGGAGCCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTG
CAGGGGAAATGGAACATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTG
AGAACTCTAATATTGGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTG
CTGCCAGTTCCCTGGATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGG
AAACTTCACGAAGTCGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAG
ATGGATTAGAACCTTATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATG
TAATGCCACACCAGAACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACG
ATAAACTTTGTGCAGACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCG
AGTCCGAAAGCACCACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCT
CTGACCCTGTAAGGGATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAG
ATAAACCTTTAACAAATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAG
TAATATCAGACAGTACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGA
AAGAAAAGGGAACAGCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGC
CACTAGAAGACAGGGCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTG
GTGGAGAGCATGAGGGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTA
AGGCCACTTTGGCTTTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGG
ATAAAGCGGTGACCTGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAG
ATACTCAACAATTTCATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTG
CCTTTCTTAAGGCAGAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGC
CACCAGGAGCAAGTCTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAG
ATGGGTCTGATGGGTCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTA
GTGCCTGTGAGGTGAGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATAT
CACACAACACCCAAGACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACA
AAGCTGTGACTGACCCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCT
GTACCATGGGTGACGCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACA
TGGAGCTCTCAGCCCATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCT
CTCTACCTTGCATGGTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTG
TCATCGAACAAGTCAAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCA
CTAAAGGACTAGAGAGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCA
CGGGGAGCCTTGCAGGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGC
CAGACGTGAAAGCTGAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGA
TGAAGCAAGGCCCAATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCA
AGCAGAGCCCAGAATGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGA
GTGATTCTGACCTCTTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCA
CCGGATCCAGTTCATCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGC
CAAACAGGTCAAGAGATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTG
ACCCAGGCGACGTGGAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTT
CTCCCTTCCGGAGGCACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTTCAATGCGAGTTCTTGGGG
ATGTTGTCAGGAGACCTCCCATTCATAGGAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCAT
CTCTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAG
AGGATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACAT
CAGCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCT
TCCACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAAT
GGAAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAA
AAGATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTG
TTGTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACA
AAGGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGC
CCACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAA
TATTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACA
TGTCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATG
AGGGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGA
TAATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATC
ATGTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGT
TCCCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTG
AAAAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCA
AGTTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGA
TGAGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAA
GAATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAG
ACAGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTG
GTCAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAG
AGGTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAA
CAGTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAG
AGATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATG
AAGATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGG
ACCAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCC
CAACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGG
AGATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCG
TTTCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATG
ATGGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTG
AGCAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACC
AGAAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGA
AGCAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTG
AGAGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGG
AGCTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGC
GCCGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGG
TTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGG
TGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACC
CACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCT
TCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGG
CCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACT
TGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCT
ACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTAT
GGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGA
AGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAA
GGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTG
ACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCA
CATGGATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCT
GTGATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGT
TTACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAG
AGGAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACT
TCTACTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAG
CACAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCA
GCCCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTT
CACATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGT

>3313_3313_11_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612032_ENST00000340058_length(amino acids)=3046AA_BP=2686
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRPPIHRRSFSLEGLTGGAGVGNKPSSSL
EVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFHSTFH
NTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSSIPVV
GPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETATTPIF
ANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESWSRII
DSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVDKSEK
NFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRI
LQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGRLKEV
QAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLNRDED
EGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAINEVEI
LQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKRNSEQ
VVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEARER
ELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRKNLVL
GKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFL
RESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYV
KRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRP

--------------------------------------------------------------
>3313_3313_12_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612032_ENST00000355710_length(transcript)=11444nt_BP=8153nt
GAGCGGCCGCCTATTGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGCCGCACGTGTCCT
GGGTCATGAAACTTAATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGATG
ATGTAGTGTTTTACTTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTG
CTCCTGGTCATGATTGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACT
TTCATTTCGTCCAGGATGAAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTC
TTGACCAGTCAGGACCCCCATCTGGGGATGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGT
GGAATGTATTGGGGACAGATCAGAGTTTGCATGATGCTGGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGT
TGACGTGGTTCCTGTTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTATCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGG
AGCGAGGCTATCACAAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGACTCCTGGAGCAGTTTATCCTATGAAATACCGT
ATGGAGACTGTTCTGTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCACATCATGAACACCCATTTCCTG
GAGACGGTTGCACTGGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGGACAGTCTTATGC
CCTTAATGATGACAGCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCAGC
GACTTTCTTCTTCTGAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCA
TAGTTGAGGAGGAGAATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTG
TGGACTCTGGAACTGTATCTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTG
GAAACAGAAATGAAGAAACTGGAACAAAATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAG
ACTTGGTCATGGAGCCAGGCACAGCCCAGTATTCCTCTGGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTG
CAGGGGAAATGGAACATGGGCTCATGAACCCAGATGCCACTGTTTGGAAGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTG
AGAACTCTAATATTGGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGTGGATAAAATCAGTGTTCCAAACTGTGCCCCTG
CTGCCAGTTCCCTGGATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCCACTGAAAAAACAGCAGAAACGG
AAACTTCACGAAGTCGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAGACAAGATTTCAG
ATGGATTAGAACCTTATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGATG
TAATGCCACACCAGAACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACG
ATAAACTTTGTGCAGACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCG
AGTCCGAAAGCACCACAGCAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCT
CTGACCCTGTAAGGGATACCCAGGAACGTGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAG
ATAAACCTTTAACAAATATGCTTGAGGTGGTTTCACATCCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAG
TAATATCAGACAGTACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAATCAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGA
AAGAAAAGGGAACAGCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCCAGATGGAAATTCGAATGAGCCTGATACGCGGC
CACTAGAAGACAGGGCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGGAATACCAGTCTCACAGGACTTG
GTGGAGAGCATGAGGGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGCAAAGTGTGGGTA
AGGCCACTTTGGCTTTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAAGG
ATAAAGCGGTGACCTGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAG
ATACTCAACAATTTCATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTG
CCTTTCTTAAGGCAGAAACTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGC
CACCAGGAGCAAGTCTGGCCACAGAGTCAAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAG
ATGGGTCTGATGGGTCCGATGCTCTTAACTGCAGTCAGCCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTA
GTGCCTGTGAGGTGAGTGGAGATGTGACGGTGGATGTTACAGGGGTTAATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATAT
CACACAACACCCAAGACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGCCGTTCTAGGTTTGCCAGTGGCTCTACAGGACA
AAGCTGTGACTGACCCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAGCTGGAGGGAGCAGACCACAGCT
GTACCATGGGTGACGCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGCTCCCCACAGACA
TGGAGCTCTCAGCCCATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCCCT
CTCTACCTTGCATGGTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTG
TCATCGAACAAGTCAAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCA
CTAAAGGACTAGAGAGTGCTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCA
CGGGGAGCCTTGCAGGATGTTTTGCTGGAAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGC
CAGACGTGAAAGCTGAAGATGAAGTGGATTTTAGAGCAAGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGA
TGAAGCAAGGCCCAATGACCCAGGCGATAAACCGAGAAAACTGGTGTACAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCA
AGCAGAGCCCAGAATGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTCAAAACAAGGTGTACTTAAAAGAGAATCTGGGA
GTGATTCTGACCTCTTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAAGAGCATTTGGCCTGTGATATCA
CCGGATCCAGTTCATCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCCAGATTTTAAAGC
CAAACAGGTCAAGAGATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGCTG
ACCCAGGCGACGTGGAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTT
CTCCCTTCCGGAGGCACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTTCAATGCGAGTTCTTGGGG
ATGTTGTCAGGAGACCTCCCATTCATAGGAGAAGTTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCAT
CTCTAGAAGTAAGCTCTGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAG
AGGATCTGGAGTCAGACCAGAGAGAACATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACAT
CAGCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCT
TCCACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAAT
GGAAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAA
AAGATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCAGTTCCATTCCTG
TTGTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCACA
AAGGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGC
CCACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAA
TATTTGCCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACA
TGTCAAACACCTGGAAATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATG
AGGGAGTAGGTACAGACATGAATGAAGGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGA
TAATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATC
ATGTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGT
TCCCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTG
AAAAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGAAGACATATGGCA
AGTTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAAGA
TGAGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAA
GAATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAG
ACAGCAAAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTG
GTCAGATGTTTGCCAAGGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAG
AGGTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAA
CAGTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAG
AGATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATG
AAGATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTAAAAGAACAACTTCACCAGAAGG
ACCAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAGAGGATTGCTCCC
CAACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGTGG
AGATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCG
TTTCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATG
ATGGCCAAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTG
AGCAGGTTGTCCAGAGCGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACC
AGAAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGA
AGCAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTG
AGAGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGG
AGCTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGC
GCCGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGG
TTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGG
TGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACC
CACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCT
TCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGG
CCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACT
TGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCT
ACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTAT
GGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGA
AGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAA
GGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTG
ACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCA
CATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACA
CTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTT
AACATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCAC
ATTGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGG
TGATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCA
CCCAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGG
ACCTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAA
TGCTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGG
AAGAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACA
TTTGGTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGG
GAAGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAA
CAGTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGC
ACACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTA
TCAACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTC
TGATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCT
ACAAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACA
CTCCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCG
GATTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATT
TCACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAG
AGGGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAA
TATCTATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTA
TTAAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTG
ATGGGGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCT
ACTGGAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTG
TAAAATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAAT

>3313_3313_12_AKAP13-RET_AKAP13_chr15_86284726_ENST00000394518_RET_chr10_43612032_ENST00000355710_length(amino acids)=3088AA_BP=2686
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFH
FVQDEAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGD
GCTGPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTKSSGMPTDQESLSSGDAVLQRDL
VMEPGTAQYSSGGELGGISTTNVSTPDTAGEMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDGLEPYTLLAAGIGEAMSPSDLALLGLEEDVM
PHQNSETNSSHAQSQKGKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVTKDDALSFVPSQKE
KGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISADCAKDKALQLSNSPGASSAF
LKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGKLEGADHSCT
MGDAEEAQIDDEAHPVLLQPVAKELPTDMELSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAGREEPEKIILPVQGPEPAAEMPD
VKAEDEVDFRASSISEEVAVGSIAATLKMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADP
GDVEEEEMDSITEVPANCSVLRSSMRSLSPFRRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRPPIHRRSFSLEGLTGGAGVGNKPSSSL
EVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFHSTFH
NTSANLTESITEENYNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSSIPVV
GPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPTVIMRNKPSQPKERPRSAVLLVDETATTPIF
ANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESWSRII
DSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFPCLDELISIHSQFFQRILERKKESLVDKSEK
NFLIKRIGDVLVNQFSGENAERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRI
LQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLKRKKLVRDGSVFLKNAAGRLKEV
QAVLLTDILVFLQEKDQKYIFASLDQKSTVISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLNRDED
EGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSAINEVEI
LQGLVSGNLGGTLGPTVSSPIEQDVVGPVSLPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKRNSEQ
VVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEARER
ELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQEDPKWEFPRKNLVL
GKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFL
RESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYV
KRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRP
VFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AKAP13-RET


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneAKAP13chr15:86284726chr10:43612031ENST00000361243+35371919_28132690.02818.0ESR1
HgeneAKAP13chr15:86284726chr10:43612031ENST00000394518+35371919_28132686.02814.0ESR1
HgeneAKAP13chr15:86284726chr10:43612031ENST00000560302+141919_28130180.0ESR1
HgeneAKAP13chr15:86284726chr10:43612032ENST00000361243+35371919_28132690.02818.0ESR1
HgeneAKAP13chr15:86284726chr10:43612032ENST00000394518+35371919_28132686.02814.0ESR1
HgeneAKAP13chr15:86284726chr10:43612032ENST00000560302+141919_28130180.0ESR1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AKAP13-RET


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AKAP13-RET


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource