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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:GLG1-APPBP2 (FusionGDB2 ID:33239)

Fusion Gene Summary for GLG1-APPBP2

Fusion gene summary

Fusion gene information	Fusion gene name: GLG1-APPBP2
	Fusion gene ID: 33239
		Hgene	Tgene
	Gene symbol	GLG1	APPBP2
	Gene ID	2734	10513
	Gene name	golgi glycoprotein 1	amyloid beta precursor protein binding protein 2
	Synonyms	CFR-1\|ESL-1\|MG-160\|MG160	APP-BP2\|HS.84084\|PAT1
	Cytomap	16q23.1	17q23.2
	Type of gene	protein-coding	protein-coding
	Description	Golgi apparatus protein 1E-selectin ligand 1cysteine-rich fibroblast growth factor receptorgolgi sialoglycoprotein MG-160	amyloid protein-binding protein 2amyloid beta precursor protein (cytoplasmic tail) binding protein 2protein interacting with APP tail 1
	Modification date	20200313	20200313
	UniProtAcc	Q92896	Q92624
	Ensembl transtripts involved in fusion gene	ENST00000205061, ENST00000422840, ENST00000447066,	ENST00000592995, ENST00000083182,
Fusion gene scores	* DoF score	23 X 21 X 12=5796	10 X 7 X 7=490
	# samples	29	11
	** MAII score	log2(29/5796*10)=-4.320932789542 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(11/490*10)=-2.15527822547791 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: GLG1 [Title/Abstract] AND APPBP2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	GLG1(74495991)-APPBP2(58538148), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	APPBP2	GO:0046907	intracellular transport	9843960

Fusion gene breakpoints across GLG1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across APPBP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-G2-A2EF	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-

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Fusion Gene ORF analysis for GLG1-APPBP2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000205061	ENST00000592995	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-
5CDS-5UTR	ENST00000422840	ENST00000592995	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-
5CDS-5UTR	ENST00000447066	ENST00000592995	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-
In-frame	ENST00000205061	ENST00000083182	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-
In-frame	ENST00000422840	ENST00000083182	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-
In-frame	ENST00000447066	ENST00000083182	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000205061	GLG1	chr16	74495991	-	ENST00000083182	APPBP2	chr17	58538148	-	8300	3056	20	3877	1285
ENST00000422840	GLG1	chr16	74495991	-	ENST00000083182	APPBP2	chr17	58538148	-	8280	3036	0	3857	1285
ENST00000447066	GLG1	chr16	74495991	-	ENST00000083182	APPBP2	chr17	58538148	-	8265	3021	18	3842	1274

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000205061	ENST00000083182	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-	7.91E-05	0.99992096
ENST00000422840	ENST00000083182	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-	7.61E-05	0.9999238
ENST00000447066	ENST00000083182	GLG1	chr16	74495991	-	APPBP2	chr17	58538148	-	7.72E-05	0.99992275

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Fusion Genomic Features for GLG1-APPBP2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GLG1-APPBP2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:74495991/chr17:58538148)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
GLG1 Q92896	APPBP2 Q92624
FUNCTION: Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). {ECO:0000269\|PubMed:8985126}.	FUNCTION: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface. {ECO:0000269\|PubMed:9843960}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

54_57

1012

1204.0

Compositional bias

Note=Poly-Gly

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

71_86

1012

1204.0

Compositional bias

Note=Poly-Gln

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

54_57

1012

1180.0

Compositional bias

Note=Poly-Gly

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

71_86

1012

1180.0

Compositional bias

Note=Poly-Gln

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

54_57

1001

1193.0

Compositional bias

Note=Poly-Gly

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

71_86

1001

1193.0

Compositional bias

Note=Poly-Gln

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

116_149

1012

1204.0

Repeat

Note=Cys-rich GLG1 1

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

150_212

1012

1204.0

Repeat

Note=Cys-rich GLG1 2

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

215_278

1012

1204.0

Repeat

Note=Cys-rich GLG1 3

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

286_346

1012

1204.0

Repeat

Note=Cys-rich GLG1 4

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

347_413

1012

1204.0

Repeat

Note=Cys-rich GLG1 5

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

414_473

1012

1204.0

Repeat

Note=Cys-rich GLG1 6

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

475_537

1012

1204.0

Repeat

Note=Cys-rich GLG1 7

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

538_604

1012

1204.0

Repeat

Note=Cys-rich GLG1 8

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

609_668

1012

1204.0

Repeat

Note=Cys-rich GLG1 9

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

670_728

1012

1204.0

Repeat

Note=Cys-rich GLG1 10

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

729_788

1012

1204.0

Repeat

Note=Cys-rich GLG1 11

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

796_856

1012

1204.0

Repeat

Note=Cys-rich GLG1 12

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

858_911

1012

1204.0

Repeat

Note=Cys-rich GLG1 13

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

912_979

1012

1204.0

Repeat

Note=Cys-rich GLG1 14

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

116_149

1012

1180.0

Repeat

Note=Cys-rich GLG1 1

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

150_212

1012

1180.0

Repeat

Note=Cys-rich GLG1 2

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

215_278

1012

1180.0

Repeat

Note=Cys-rich GLG1 3

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

286_346

1012

1180.0

Repeat

Note=Cys-rich GLG1 4

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

347_413

1012

1180.0

Repeat

Note=Cys-rich GLG1 5

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

414_473

1012

1180.0

Repeat

Note=Cys-rich GLG1 6

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

475_537

1012

1180.0

Repeat

Note=Cys-rich GLG1 7

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

538_604

1012

1180.0

Repeat

Note=Cys-rich GLG1 8

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

609_668

1012

1180.0

Repeat

Note=Cys-rich GLG1 9

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

670_728

1012

1180.0

Repeat

Note=Cys-rich GLG1 10

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

729_788

1012

1180.0

Repeat

Note=Cys-rich GLG1 11

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

796_856

1012

1180.0

Repeat

Note=Cys-rich GLG1 12

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

858_911

1012

1180.0

Repeat

Note=Cys-rich GLG1 13

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

912_979

1012

1180.0

Repeat

Note=Cys-rich GLG1 14

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

116_149

1001

1193.0

Repeat

Note=Cys-rich GLG1 1

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

150_212

1001

1193.0

Repeat

Note=Cys-rich GLG1 2

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

215_278

1001

1193.0

Repeat

Note=Cys-rich GLG1 3

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

286_346

1001

1193.0

Repeat

Note=Cys-rich GLG1 4

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

347_413

1001

1193.0

Repeat

Note=Cys-rich GLG1 5

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

414_473

1001

1193.0

Repeat

Note=Cys-rich GLG1 6

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

475_537

1001

1193.0

Repeat

Note=Cys-rich GLG1 7

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

538_604

1001

1193.0

Repeat

Note=Cys-rich GLG1 8

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

609_668

1001

1193.0

Repeat

Note=Cys-rich GLG1 9

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

670_728

1001

1193.0

Repeat

Note=Cys-rich GLG1 10

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

729_788

1001

1193.0

Repeat

Note=Cys-rich GLG1 11

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

796_856

1001

1193.0

Repeat

Note=Cys-rich GLG1 12

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

858_911

1001

1193.0

Repeat

Note=Cys-rich GLG1 13

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

912_979

1001

1193.0

Repeat

Note=Cys-rich GLG1 14

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

333_367

312

586.0

Repeat

Note=TPR 5

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

429_462

312

586.0

Repeat

Note=TPR 6

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

471_505

312

586.0

Repeat

Note=TPR 7

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

514_547

312

586.0

Repeat

Note=TPR 8

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

1041_1101

1012

1204.0

Repeat

Note=Cys-rich GLG1 16

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

980_1035

1012

1204.0

Repeat

Note=Cys-rich GLG1 15

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

1041_1101

1012

1180.0

Repeat

Note=Cys-rich GLG1 16

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

980_1035

1012

1180.0

Repeat

Note=Cys-rich GLG1 15

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

1041_1101

1001

1193.0

Repeat

Note=Cys-rich GLG1 16

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

980_1035

1001

1193.0

Repeat

Note=Cys-rich GLG1 15

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

1167_1179

1012

1204.0

Topological domain

Cytoplasmic

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

30_1145

1012

1204.0

Topological domain

Extracellular

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

1167_1179

1012

1180.0

Topological domain

Cytoplasmic

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

30_1145

1012

1180.0

Topological domain

Extracellular

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

1167_1179

1001

1193.0

Topological domain

Cytoplasmic

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

30_1145

1001

1193.0

Topological domain

Extracellular

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000205061

1146_1166

1012

1204.0

Transmembrane

Helical

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000422840

1146_1166

1012

1180.0

Transmembrane

Helical

Hgene

GLG1

chr16:74495991

chr17:58538148

ENST00000447066

1146_1166

1001

1193.0

Transmembrane

Helical

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

120_153

312

586.0

Repeat

Note=TPR 2

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

206_239

312

586.0

Repeat

Note=TPR 3

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

288_321

312

586.0

Repeat

Note=TPR 4

Tgene

APPBP2

chr16:74495991

chr17:58538148

ENST00000083182

50_83

312

586.0

Repeat

Note=TPR 1

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Fusion Gene Sequence for GLG1-APPBP2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>33239_33239_1_GLG1-APPBP2_GLG1_chr16_74495991_ENST00000205061_APPBP2_chr17_58538148_ENST00000083182_length(transcript)=8300nt_BP=3056nt
GAGCTCGCCGCGGACTCAAGATGGCGGCGTGTGGACGTGTACGGAGGATGTTCCGCTTGTCGGCGGCGCTGCATCTGCTGCTGCTATTCG
CGGCCGGGGCCGAGAAACTCCCCGGCCAGGGCGTCCACAGCCAGGGCCAGGGTCCCGGGGCCAACTTTGTGTCCTTCGTAGGGCAGGCCG
GAGGCGGCGGCCCGGCGGGTCAGCAGCTGCCCCAGCTGCCTCAGTCATCGCAGCTTCAGCAGCAACAGCAGCAGCAGCAACAGCAACAGC
AGCCTCAGCCGCCGCAGCCGCCTTTCCCGGCGGGTGGGCCTCCGGCCCGGCGGGGAGGAGCGGGGGCTGGTGGGGGCTGGAAGCTGGCGG
AGGAAGAGTCCTGCAGGGAGGACGTGACCCGCGTGTGCCCTAAGCACACCTGGAGCAACAACCTGGCGGTGCTCGAGTGCCTGCAGGATG
TGAGGGAGCCTGAAAATGAAATTTCTTCAGACTGCAATCATTTGTTGTGGAATTATAAGCTGAACCTAACTACAGATCCCAAATTTGAAT
CTGTGGCCAGAGAGGTTTGCAAATCTACTATAACAGAGATTAAAGAATGTGCTGATGAACCGGTTGGAAAAGGTTACATGGTTTCCTGCT
TGGTGGATCACCGAGGCAACATCACTGAGTATCAGTGTCACCAGTACATTACCAAGATGACGGCCATCATTTTTAGTGATTACCGTTTAA
TCTGTGGCTTCATGGATGACTGCAAAAATGACATCAACATTCTGAAATGTGGCAGTATTCGGCTTGGAGAAAAGGATGCACATTCACAAG
GTGAGGTGGTATCATGCTTGGAGAAAGGCCTGGTGAAAGAAGCAGAAGAAAGAGAACCCAAGATTCAAGTTTCTGAACTCTGCAAGAAAG
CCATTCTCCGGGTGGCTGAGCTGTCATCGGATGACTTTCACTTAGACCGGCATTTATATTTTGCTTGCCGAGATGATCGGGAGCGTTTTT
GTGAAAATACACAAGCTGGTGAGGGCAGAGTGTATAAGTGCCTCTTTAACCATAAATTTGAAGAATCCATGAGTGAAAAGTGTCGAGAAG
CACTTACAACCCGCCAAAAGCTGATTGCCCAGGATTATAAAGTCAGTTATTCATTGGCCAAATCCTGTAAAAGTGACTTGAAGAAATACC
GGTGCAATGTGGAAAACCTTCCGCGATCGCGTGAAGCCAGGCTCTCCTACTTGTTAATGTGCCTGGAGTCAGCTGTACACAGAGGGCGAC
AAGTCAGCAGTGAGTGCCAGGGGGAGATGCTGGATTACCGACGCATGTTGATGGAAGACTTTTCTCTGAGCCCTGAGATCATCCTAAGCT
GTCGGGGGGAGATTGAACACCATTGTTCCGGATTACATCGAAAAGGGCGGACCCTACACTGTCTGATGAAAGTAGTTCGAGGGGAGAAGG
GGAACCTTGGAATGAACTGCCAGCAGGCGCTTCAAACACTGATTCAGGAGACTGACCCTGGTGCAGATTACCGCATTGATCGAGCTTTGA
ATGAAGCTTGTGAATCTGTAATCCAGACAGCCTGCAAACATATAAGATCTGGAGACCCAATGATCTTGTCGTGCCTGATGGAACATTTAT
ACACAGAGAAGATGGTAGAAGACTGTGAACACCGTCTCTTAGAGCTGCAGTATTTCATCTCCCGGGATTGGAAGCTGGACCCTGTCCTGT
ACCGCAAGTGCCAGGGAGACGCTTCTCGTCTTTGCCACACCCACGGTTGGAATGAGACCAGTGAATTTATGCCTCAGGGAGCTGTGTTCT
CTTGTTTATACAGACACGCCTACCGCACTGAGGAACAGGGAAGGAGGCTCTCACGGGAGTGCCGAGCTGAAGTCCAAAGGATCCTACACC
AGCGTGCCATGGATGTCAAGCTGGATCCTGCCCTCCAGGATAAGTGCCTGATTGATCTGGGAAAATGGTGCAGTGAGAAAACAGAGACTG
GACAGGAGCTGGAGTGCCTTCAGGACCATCTGGATGACTTGGTGGTGGAGTGTAGAGATATAGTTGGCAACCTCACTGAGTTAGAATCAG
AGGATATTCAAATAGAAGCCTTGCTGATGAGAGCCTGTGAGCCCATAATTCAGAACTTCTGCCACGATGTGGCAGATAACCAGATAGACT
CTGGGGACCTGATGGAGTGTCTGATACAGAACAAACACCAGAAGGACATGAACGAGAAGTGTGCCATCGGAGTTACCCACTTCCAGCTGG
TGCAGATGAAGGATTTTCGGTTTTCTTACAAGTTTAAAATGGCCTGCAAGGAGGACGTGTTGAAGCTTTGCCCAAACATAAAAAAGAAGG
TGGACGTGGTGATCTGCCTGAGCACGACCGTGCGCAATGACACTCTGCAGGAAGCCAAGGAGCACAGGGTGTCCCTGAAGTGCCGCAGGC
AGCTCCGTGTGGAGGAGCTGGAGATGACGGAGGACATCCGCTTGGAGCCAGATCTATACGAAGCCTGCAAGAGTGACATCAAAAACTTCT
GTTCCGCTGTGCAATATGGCAACGCTCAGATTATCGAATGTCTGAAAGAAAACAAGAAGCAGCTAAGCACCCGCTGCCACCAAAAAGTAT
TTAAGCTGCAGGAGACAGAGATGATGGACCCAGAGCTAGACTACACCCTCATGAGGGTCTGCAAGCAGATGATAAAGAGGTTCTGTCCGG
AAGCAGATTCTAAAACCATGTTGCAGTGCTTGAAGCAAAATAAAAACAGTGAATTGATGGATCCCAAATGCAAACAGATGATAACCAAGC
GCCAGATCACCCAGAACACAGATTACCGCTTAAACCCCATGTTAAGAAAAGCCTGTAAAGCTGACATTCCTAAATTCTGTCACGGTATCC
TGACTAAGGCCAAGGATGATTCAGAATTAGAAGGACAAGTCATCTCTTGCCTGAAGCTGAGATATGCTGACCAGCGCCTGTCTTCAGACT
GTGAAGACCAGATCCGAATCATTATCCAGGAGTCCGCCCTGGACTACCGCCTGGATCCTCAGCTCCAGCTGCACTGCTCAGACGAGGCAG
CCCTTGACATTAGACAGTCAGTGTTTGGTGGCAAAAATATCCACGTAGCAACAGCTCATGAAGATTTGGCCTACTCTTCTTATGTCCACC
AGTATAGCTCTGGGAAATTTGACAATGCACTATTTCATGCAGAAAGAGCTATTGGTATCATTACCCACATCCTACCTGAAGATCATCTTC
TTTTGGCTTCTTCAAAGAGGGTGAAAGCACTTATTTTAGAGGAGATTGCAATTGATTGTCATAATAAGGAAACTGAACAGAGGCTGCTTC
AAGAAGCTCATGATTTGCACCTGTCTTCACTCCAACTAGCTAAAAAAGCTTTTGGGGAATTTAATGTACAGACTGCAAAACACTATGGAA
ACCTTGGAAGACTTTATCAGTCAATGAGAAAATTTAAGGAAGCTGAAGAAATGCACATCAAAGCAATTCAGATTAAAGAACAACTTCTTG
GTCAAGAAGATTATGAAGTAGCCCTTTCAGTGGGACATCTGGCTTCTTTATATAATTATGACATGAATCAGTATGAAAATGCTGAGAAAC
TTTATTTGCGATCTATAGCAATTGGGAAGAAACTTTTTGGTGAGGGCTACAGTGGACTAGAATATGATTATCGAGGTCTCATTAAACTTT
ACAACTCCATTGGAAATTACGAGAAAGTGTTTGAATATCACAATGTTCTGTCTAACTGGAACCGGTTGCGAGATCGGCAATATTCAGTGA
CAGATGCTCTTGAAGATGTCAGCACCAGCCCCCAGTCCACTGAAGAAGTGGTGCAGTCCTTCCTGATTTCTCAGAATGTCGAGGGACCGA
GCTGCTGAGGGAGGACCTCAGTTAACCAATTACCTTTTCCCGGATTCCAGGGAATTCATACTGTGAAATCAAAACCATGTTGTTTTGGGG
GGCTGGAATTTGCATTGAAACACTGGTCCAGTCCATTGAAGACCCTATTTTGGGTGATCCCTATCTTGCAGAATGTCTGTAGGAATAAGC
ATATATTCAGTTATATTCAGCATGTACCGCATGTGTAAGTAGTCTGGCCCACATTTTCAACCTAGTAGAACAAACAACAGGAAATCTTTT
TTTTGTTGTTTTTAAAAAATTCATTTTGCAGAAAGCCTGAAAGAAAAAAAATACCCCTAAATAAAACTATTTAAGAGTTTAAAAGAGTTG
CATTCTTATTATGTAAGGATGATTTTAACAACTTTTTAATATGTAATTCTTCCATGTGGAGGTATTCAATACTGTAGTGTAAAGAAATTT
TATGCGGAAAATCTTTATATGCAGTATAGAAAAGTTAACACAAGTACTAATAAAAGAGGGACATCCCGACTTACGTTTTTCTACCTTGCC
CAGATAAGTGGATACAACCACTCTATATTACAAGGAAAGGACTGTCAGATTCATCTGAACTGGACCAGTGTTGATCTGTAATGTAATAGA
AAATCTGATAGACCAGCACTTCTGACTTTTTTTTTTTTGGTACAACAATGCAAGATGCTCTGATAGCATTTGCTAACAGGACCAGGAGGA
TCTAAAAAGGACCAGCCTAATGTAGAAGGTGGTTACTTGGACCAGAGGCTTTAGATTATTATTTTAGATCCTACATATACTTTTATCAGT
AGAATGATTTCATTTAGATGTATAATGAAAAAGGATAATGCAAAAATTATGTAATAGATACCAAATTAGGGAAGTTTGGCAATTTCAATG
GCATATTTTTAGTCAAGGTACACAGATGGCAGTGCCATAAGCAAGTCTATAAATATCGGCTGCAGCCATCCCCCTCATTTTAAATGTTGC
CCTAATAATCAATGCAGTTAACAAGTATATTGGCTGTGTGTCATGAAATAGTTCATGTTCAGATGGAAATGTTAGGTTACTGTATGGTTT
ATGGAGATTAATGAAAATGAATGCCCAAAAATAAGTCTTAGAAAATCCTCCATTTTTATGGTAAATAGTAATACAACTAGGTCATTTCAT
TTGAAATCTAGGAGTCAAATGGAAAGATCCCCTAATAATACACCTATTTCACTAACTTGTCTTTCTGTTTATTGGGTTTTGATTTGATTT
TTTGTAAGCCAGTCAGGTTATTTAATGATGAGGTAATAATCAAATTTAAGAATTTGTGACATGTAGCAATTCAAGAAACAAAAAGGTATT
TTGCTGTTACCTCAATTCTTACTGTAGTAGCCCATCTGATGCTTCTATAGTTAAGAATCTGGGTTCCCCCCCTATTTTCAGGGGTTCATG
ACTTGGCTGTTAAAGATGTTGCTCCTAGCTAATGCTTGGAGTAGTCTGTGGGTGAATGGATGTGTGTTGAATTTTAGTTTTCTTTTAACA
TGCATGTTGGGTGAGAGGGGAAAAAAATCTAAGCTGTCTGCCACATTGAGTACAGAAAAGTTGTAGATTTCAAATTTTATTAATATTTTA
AGCACTTTTTTGAACTTCCCAACCTTGTTTGAAGCTGTTATTTGCAGTCCTATTAGTTTTGAGCCATTGCATTTAAGTTCCCTAGGAGGG
GGTTGGTTGGGGGATGTACTGAAAGAGATGAAGCAAACCCACACCCTAAGATGGTAACTGTGTGATTTAGAAACCTGAGTTTACTCCTCA
AATCGAATTATTTTCTTTTTAAATTTTGGAAAGAGTAAATTGACGTACTTGCAGTTTATGAAGCTGCCCCCCACCCCTCAGTTAATTGCA
GTCTAATGTCAAGAGGCACTTCTTTATTAATTACCAAATAGTCTTTGTGACCAAGGACTAACATTTTTAAGTTACTCAGCTCTATCCTCA
TGGGCCTATATATTTAATACCTCCAAAGATATTTTCAGGATAGGCTTTGTATACTTTTATTGGTTATTTAGAATCCAGTGGTATGTTTGT
GGTATAGGAATGTCATGGTAAATTGTTTTTCAATAAATATTTTGAAACATGTTTCCATATGAAGTTTTTTTTTCAATCTGTATTTTTTGG
TTTTGTGCACATACAGCATTTCCTAGGATAAAAATAAACAAATGACTTACAGCCTCATCCTCCCTAACTCCATTTGAACTCAACTTAGCT
CACACTCAGTGATAAAACAACATGGTATGTAGAAGCCTAGGATCACAGGGTGATAATGTCAATTGGCAGCCAGTTGTGTTTTTTTGAAAC
ATCATTATTGGCAGTTTCTCCTTATCACCACTGCTTTAATGTAGTTTTTTTGTAAATCCATATACTTTAATGCATACACTCTAGCTTAAG
AAAACATTGCCATTTTGGTTAGGGATATGACTTAATGTGCTATTATTTCTGGTTCTAATGAAGAATAATACCCTATGACTTTAAGTGTAA
GATTCATCCTTTAAGTAGGGATGTTTAGGATAAGTTAGATGTGTGCCACTATGATTTATTGGGTTTCTTAAAAATCTTGAAGAAAATAAT
AAAATTTATCTCACAATAAGTTAACTTGCGCAAACTTTTTACATATGGTGAGGTGCGTAAGGAAGCCCTGGCCAACTTAAAGATTTTTCT
GGAGGTTCAGCAAAGTTATGTTAAATTAGGGGCCTTTGGTCTCATCCTTCTCTGACTCTTCTACCCAGTCTTTTCCTAAAGTTCGGTGCT
ACTCCAGTTGGGTGCATCAGGGAGCTCCGTCAGCACTCGCATGTGTCGCTCAGGTGGCCACTCATGCCTGCATTCCATTTAATAGAGTCA
ATTGGAATTTTTAGAGCATAATCTTTATGGATCCTCAAAGCTGACTTTGCCAAAGGGATTGAGACCCTTACTACCATCAAATCTCTGTCT
CTGCTTGGTTAAAAATTGGCTCACTATTGCTTTGTAGTAACCCCTGCCCAGGTATTTTTTCACTTGTGAAAATAATTTGAGAAAGACCTT
TGTTCCTAGCCTGTTGGGAAAAGTTTATAATTTTATGAAAATTAAGTACAGAGGCTGCGATCTTAGAAATAATGAAGGTGCCATTTGGCT
GCTCCTTAATAGTGCAGACAGAAAACTGCAGTGAACACATGCCAAAACATGATTGAAGCCTTTGGCTGAAACTTTATACATAGAAATAAT
GATTTGCTCATAACAGGTATCATTAACTGCCACTTTTTATGTTTTCCCTAGAATTTGTAGCCTTGCTGCTTGCTTTTCTTCTGGGTGGCA
AAGTTACTACTGGAAAAACACTATAAGTACAAAGTTTTTGGGGTTTTATCTTTGCTTTAGAAGTGGATGTGTACTTCACCTCTTGGCTGT
GGAGGAACTTAGTTGCCAGGAAATTTTTTTTTTTTTTTTCAGACGGAGTTTCGCTCTTGTTGCCCAGGCTGGGAGGGCAATGGCACCGTC
TTGGCTCACTGCAACCTCCGCCTCCCGGGTTCCAGCGATTCTCCTGCCTCAGCCTTCCGAGTAGCTGGGATTACAGGCTCCTGCCACCAC
GCCTGGCTAGGAAATTTTTTGTTGTTAATATGACATTTGGATTAATCTCCAGCTTCAACAGTACTTCTTTTGTCCATAAATCTCAGGAAT
GTTTTAGGCAGAAAACTGGTTTTACCCTGTTGATAATCAGAAGGAGTGTGCTTTAGGATTTATTGCATAATACTATTCTTTAATTGCAAT
CCTAGGTATCTATAGCATGAGTGGCCTTAGTGAGTTTGTTGAAGTGCACATGTTTTTCAAGAGTAAAATTTAAGATTAAAAATATATCCT
ATATATAGATATCTAGAAAACTTGGTTTGTGGTGCACAGTTAAGTGTTGGATCACTAAATAACCATTGCAGGTACCGTTTGTGTAACATT
ACTCATTTCTGTATATTCCTTTTATGGGAAGATATTTTGCCATGGTAACTAAAACTTTTCAGTTCTACTTTTATGATGTGAATGAATGCT
ACGTTTTATTAAATATTACCAGGTCAGTACTATTTTTATACTTTATTAAGCAACAGGGGATTTTAGTTTAATAGGCTCAAAATAAAAAGT
TCTTAATGGAACAGTTAAAAACAAAACACTAACAATCTTTACGTGAAAATCCCCACTAATAGTGCCACAATAATTTCTATAGAAATATCT
AAGGTCATTAAATAGATTTTTGAAGACGGTTCTTCATTGTGTCAGGATGACCTTTCATATCATTCTCACCAACTTGTAGTGCCCACCGTT
ATTTGTAACTATTAAACCATACTAAGTATGTTTGTAACCAGCATTGTGATATATTCTGTACTTGTATTGCTAAAAATGAATTATTGACCT

>33239_33239_1_GLG1-APPBP2_GLG1_chr16_74495991_ENST00000205061_APPBP2_chr17_58538148_ENST00000083182_length(amino acids)=1285AA_BP=1012
MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQQQQQQQQQQPQPPQP
PFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTTDPKFESVAREVC
KSTITEIKECADEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIFSDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCL
EKGLVKEAEEREPKIQVSELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQK
LIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEH
HCSGLHRKGRTLHCLMKVVRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVE
DCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSEFMPQGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVK
LDPALQDKCLIDLGKWCSEKTETGQELECLQDHLDDLVVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMEC
LIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRRQLRVEEL
EMTEDIRLEPDLYEACKSDIKNFCSAVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTM
LQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPMLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRI
IIQESALDYRLDPQLQLHCSDEAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKR
VKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEV
ALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDV

--------------------------------------------------------------
>33239_33239_2_GLG1-APPBP2_GLG1_chr16_74495991_ENST00000422840_APPBP2_chr17_58538148_ENST00000083182_length(transcript)=8280nt_BP=3036nt
ATGGCGGCGTGTGGACGTGTACGGAGGATGTTCCGCTTGTCGGCGGCGCTGCATCTGCTGCTGCTATTCGCGGCCGGGGCCGAGAAACTC
CCCGGCCAGGGCGTCCACAGCCAGGGCCAGGGTCCCGGGGCCAACTTTGTGTCCTTCGTAGGGCAGGCCGGAGGCGGCGGCCCGGCGGGT
CAGCAGCTGCCCCAGCTGCCTCAGTCATCGCAGCTTCAGCAGCAACAGCAGCAGCAGCAACAGCAACAGCAGCCTCAGCCGCCGCAGCCG
CCTTTCCCGGCGGGTGGGCCTCCGGCCCGGCGGGGAGGAGCGGGGGCTGGTGGGGGCTGGAAGCTGGCGGAGGAAGAGTCCTGCAGGGAG
GACGTGACCCGCGTGTGCCCTAAGCACACCTGGAGCAACAACCTGGCGGTGCTCGAGTGCCTGCAGGATGTGAGGGAGCCTGAAAATGAA
ATTTCTTCAGACTGCAATCATTTGTTGTGGAATTATAAGCTGAACCTAACTACAGATCCCAAATTTGAATCTGTGGCCAGAGAGGTTTGC
AAATCTACTATAACAGAGATTAAAGAATGTGCTGATGAACCGGTTGGAAAAGGTTACATGGTTTCCTGCTTGGTGGATCACCGAGGCAAC
ATCACTGAGTATCAGTGTCACCAGTACATTACCAAGATGACGGCCATCATTTTTAGTGATTACCGTTTAATCTGTGGCTTCATGGATGAC
TGCAAAAATGACATCAACATTCTGAAATGTGGCAGTATTCGGCTTGGAGAAAAGGATGCACATTCACAAGGTGAGGTGGTATCATGCTTG
GAGAAAGGCCTGGTGAAAGAAGCAGAAGAAAGAGAACCCAAGATTCAAGTTTCTGAACTCTGCAAGAAAGCCATTCTCCGGGTGGCTGAG
CTGTCATCGGATGACTTTCACTTAGACCGGCATTTATATTTTGCTTGCCGAGATGATCGGGAGCGTTTTTGTGAAAATACACAAGCTGGT
GAGGGCAGAGTGTATAAGTGCCTCTTTAACCATAAATTTGAAGAATCCATGAGTGAAAAGTGTCGAGAAGCACTTACAACCCGCCAAAAG
CTGATTGCCCAGGATTATAAAGTCAGTTATTCATTGGCCAAATCCTGTAAAAGTGACTTGAAGAAATACCGGTGCAATGTGGAAAACCTT
CCGCGATCGCGTGAAGCCAGGCTCTCCTACTTGTTAATGTGCCTGGAGTCAGCTGTACACAGAGGGCGACAAGTCAGCAGTGAGTGCCAG
GGGGAGATGCTGGATTACCGACGCATGTTGATGGAAGACTTTTCTCTGAGCCCTGAGATCATCCTAAGCTGTCGGGGGGAGATTGAACAC
CATTGTTCCGGATTACATCGAAAAGGGCGGACCCTACACTGTCTGATGAAAGTAGTTCGAGGGGAGAAGGGGAACCTTGGAATGAACTGC
CAGCAGGCGCTTCAAACACTGATTCAGGAGACTGACCCTGGTGCAGATTACCGCATTGATCGAGCTTTGAATGAAGCTTGTGAATCTGTA
ATCCAGACAGCCTGCAAACATATAAGATCTGGAGACCCAATGATCTTGTCGTGCCTGATGGAACATTTATACACAGAGAAGATGGTAGAA
GACTGTGAACACCGTCTCTTAGAGCTGCAGTATTTCATCTCCCGGGATTGGAAGCTGGACCCTGTCCTGTACCGCAAGTGCCAGGGAGAC
GCTTCTCGTCTTTGCCACACCCACGGTTGGAATGAGACCAGTGAATTTATGCCTCAGGGAGCTGTGTTCTCTTGTTTATACAGACACGCC
TACCGCACTGAGGAACAGGGAAGGAGGCTCTCACGGGAGTGCCGAGCTGAAGTCCAAAGGATCCTACACCAGCGTGCCATGGATGTCAAG
CTGGATCCTGCCCTCCAGGATAAGTGCCTGATTGATCTGGGAAAATGGTGCAGTGAGAAAACAGAGACTGGACAGGAGCTGGAGTGCCTT
CAGGACCATCTGGATGACTTGGTGGTGGAGTGTAGAGATATAGTTGGCAACCTCACTGAGTTAGAATCAGAGGATATTCAAATAGAAGCC
TTGCTGATGAGAGCCTGTGAGCCCATAATTCAGAACTTCTGCCACGATGTGGCAGATAACCAGATAGACTCTGGGGACCTGATGGAGTGT
CTGATACAGAACAAACACCAGAAGGACATGAACGAGAAGTGTGCCATCGGAGTTACCCACTTCCAGCTGGTGCAGATGAAGGATTTTCGG
TTTTCTTACAAGTTTAAAATGGCCTGCAAGGAGGACGTGTTGAAGCTTTGCCCAAACATAAAAAAGAAGGTGGACGTGGTGATCTGCCTG
AGCACGACCGTGCGCAATGACACTCTGCAGGAAGCCAAGGAGCACAGGGTGTCCCTGAAGTGCCGCAGGCAGCTCCGTGTGGAGGAGCTG
GAGATGACGGAGGACATCCGCTTGGAGCCAGATCTATACGAAGCCTGCAAGAGTGACATCAAAAACTTCTGTTCCGCTGTGCAATATGGC
AACGCTCAGATTATCGAATGTCTGAAAGAAAACAAGAAGCAGCTAAGCACCCGCTGCCACCAAAAAGTATTTAAGCTGCAGGAGACAGAG
ATGATGGACCCAGAGCTAGACTACACCCTCATGAGGGTCTGCAAGCAGATGATAAAGAGGTTCTGTCCGGAAGCAGATTCTAAAACCATG
TTGCAGTGCTTGAAGCAAAATAAAAACAGTGAATTGATGGATCCCAAATGCAAACAGATGATAACCAAGCGCCAGATCACCCAGAACACA
GATTACCGCTTAAACCCCATGTTAAGAAAAGCCTGTAAAGCTGACATTCCTAAATTCTGTCACGGTATCCTGACTAAGGCCAAGGATGAT
TCAGAATTAGAAGGACAAGTCATCTCTTGCCTGAAGCTGAGATATGCTGACCAGCGCCTGTCTTCAGACTGTGAAGACCAGATCCGAATC
ATTATCCAGGAGTCCGCCCTGGACTACCGCCTGGATCCTCAGCTCCAGCTGCACTGCTCAGACGAGGCAGCCCTTGACATTAGACAGTCA
GTGTTTGGTGGCAAAAATATCCACGTAGCAACAGCTCATGAAGATTTGGCCTACTCTTCTTATGTCCACCAGTATAGCTCTGGGAAATTT
GACAATGCACTATTTCATGCAGAAAGAGCTATTGGTATCATTACCCACATCCTACCTGAAGATCATCTTCTTTTGGCTTCTTCAAAGAGG
GTGAAAGCACTTATTTTAGAGGAGATTGCAATTGATTGTCATAATAAGGAAACTGAACAGAGGCTGCTTCAAGAAGCTCATGATTTGCAC
CTGTCTTCACTCCAACTAGCTAAAAAAGCTTTTGGGGAATTTAATGTACAGACTGCAAAACACTATGGAAACCTTGGAAGACTTTATCAG
TCAATGAGAAAATTTAAGGAAGCTGAAGAAATGCACATCAAAGCAATTCAGATTAAAGAACAACTTCTTGGTCAAGAAGATTATGAAGTA
GCCCTTTCAGTGGGACATCTGGCTTCTTTATATAATTATGACATGAATCAGTATGAAAATGCTGAGAAACTTTATTTGCGATCTATAGCA
ATTGGGAAGAAACTTTTTGGTGAGGGCTACAGTGGACTAGAATATGATTATCGAGGTCTCATTAAACTTTACAACTCCATTGGAAATTAC
GAGAAAGTGTTTGAATATCACAATGTTCTGTCTAACTGGAACCGGTTGCGAGATCGGCAATATTCAGTGACAGATGCTCTTGAAGATGTC
AGCACCAGCCCCCAGTCCACTGAAGAAGTGGTGCAGTCCTTCCTGATTTCTCAGAATGTCGAGGGACCGAGCTGCTGAGGGAGGACCTCA
GTTAACCAATTACCTTTTCCCGGATTCCAGGGAATTCATACTGTGAAATCAAAACCATGTTGTTTTGGGGGGCTGGAATTTGCATTGAAA
CACTGGTCCAGTCCATTGAAGACCCTATTTTGGGTGATCCCTATCTTGCAGAATGTCTGTAGGAATAAGCATATATTCAGTTATATTCAG
CATGTACCGCATGTGTAAGTAGTCTGGCCCACATTTTCAACCTAGTAGAACAAACAACAGGAAATCTTTTTTTTGTTGTTTTTAAAAAAT
TCATTTTGCAGAAAGCCTGAAAGAAAAAAAATACCCCTAAATAAAACTATTTAAGAGTTTAAAAGAGTTGCATTCTTATTATGTAAGGAT
GATTTTAACAACTTTTTAATATGTAATTCTTCCATGTGGAGGTATTCAATACTGTAGTGTAAAGAAATTTTATGCGGAAAATCTTTATAT
GCAGTATAGAAAAGTTAACACAAGTACTAATAAAAGAGGGACATCCCGACTTACGTTTTTCTACCTTGCCCAGATAAGTGGATACAACCA
CTCTATATTACAAGGAAAGGACTGTCAGATTCATCTGAACTGGACCAGTGTTGATCTGTAATGTAATAGAAAATCTGATAGACCAGCACT
TCTGACTTTTTTTTTTTTGGTACAACAATGCAAGATGCTCTGATAGCATTTGCTAACAGGACCAGGAGGATCTAAAAAGGACCAGCCTAA
TGTAGAAGGTGGTTACTTGGACCAGAGGCTTTAGATTATTATTTTAGATCCTACATATACTTTTATCAGTAGAATGATTTCATTTAGATG
TATAATGAAAAAGGATAATGCAAAAATTATGTAATAGATACCAAATTAGGGAAGTTTGGCAATTTCAATGGCATATTTTTAGTCAAGGTA
CACAGATGGCAGTGCCATAAGCAAGTCTATAAATATCGGCTGCAGCCATCCCCCTCATTTTAAATGTTGCCCTAATAATCAATGCAGTTA
ACAAGTATATTGGCTGTGTGTCATGAAATAGTTCATGTTCAGATGGAAATGTTAGGTTACTGTATGGTTTATGGAGATTAATGAAAATGA
ATGCCCAAAAATAAGTCTTAGAAAATCCTCCATTTTTATGGTAAATAGTAATACAACTAGGTCATTTCATTTGAAATCTAGGAGTCAAAT
GGAAAGATCCCCTAATAATACACCTATTTCACTAACTTGTCTTTCTGTTTATTGGGTTTTGATTTGATTTTTTGTAAGCCAGTCAGGTTA
TTTAATGATGAGGTAATAATCAAATTTAAGAATTTGTGACATGTAGCAATTCAAGAAACAAAAAGGTATTTTGCTGTTACCTCAATTCTT
ACTGTAGTAGCCCATCTGATGCTTCTATAGTTAAGAATCTGGGTTCCCCCCCTATTTTCAGGGGTTCATGACTTGGCTGTTAAAGATGTT
GCTCCTAGCTAATGCTTGGAGTAGTCTGTGGGTGAATGGATGTGTGTTGAATTTTAGTTTTCTTTTAACATGCATGTTGGGTGAGAGGGG
AAAAAAATCTAAGCTGTCTGCCACATTGAGTACAGAAAAGTTGTAGATTTCAAATTTTATTAATATTTTAAGCACTTTTTTGAACTTCCC
AACCTTGTTTGAAGCTGTTATTTGCAGTCCTATTAGTTTTGAGCCATTGCATTTAAGTTCCCTAGGAGGGGGTTGGTTGGGGGATGTACT
GAAAGAGATGAAGCAAACCCACACCCTAAGATGGTAACTGTGTGATTTAGAAACCTGAGTTTACTCCTCAAATCGAATTATTTTCTTTTT
AAATTTTGGAAAGAGTAAATTGACGTACTTGCAGTTTATGAAGCTGCCCCCCACCCCTCAGTTAATTGCAGTCTAATGTCAAGAGGCACT
TCTTTATTAATTACCAAATAGTCTTTGTGACCAAGGACTAACATTTTTAAGTTACTCAGCTCTATCCTCATGGGCCTATATATTTAATAC
CTCCAAAGATATTTTCAGGATAGGCTTTGTATACTTTTATTGGTTATTTAGAATCCAGTGGTATGTTTGTGGTATAGGAATGTCATGGTA
AATTGTTTTTCAATAAATATTTTGAAACATGTTTCCATATGAAGTTTTTTTTTCAATCTGTATTTTTTGGTTTTGTGCACATACAGCATT
TCCTAGGATAAAAATAAACAAATGACTTACAGCCTCATCCTCCCTAACTCCATTTGAACTCAACTTAGCTCACACTCAGTGATAAAACAA
CATGGTATGTAGAAGCCTAGGATCACAGGGTGATAATGTCAATTGGCAGCCAGTTGTGTTTTTTTGAAACATCATTATTGGCAGTTTCTC
CTTATCACCACTGCTTTAATGTAGTTTTTTTGTAAATCCATATACTTTAATGCATACACTCTAGCTTAAGAAAACATTGCCATTTTGGTT
AGGGATATGACTTAATGTGCTATTATTTCTGGTTCTAATGAAGAATAATACCCTATGACTTTAAGTGTAAGATTCATCCTTTAAGTAGGG
ATGTTTAGGATAAGTTAGATGTGTGCCACTATGATTTATTGGGTTTCTTAAAAATCTTGAAGAAAATAATAAAATTTATCTCACAATAAG
TTAACTTGCGCAAACTTTTTACATATGGTGAGGTGCGTAAGGAAGCCCTGGCCAACTTAAAGATTTTTCTGGAGGTTCAGCAAAGTTATG
TTAAATTAGGGGCCTTTGGTCTCATCCTTCTCTGACTCTTCTACCCAGTCTTTTCCTAAAGTTCGGTGCTACTCCAGTTGGGTGCATCAG
GGAGCTCCGTCAGCACTCGCATGTGTCGCTCAGGTGGCCACTCATGCCTGCATTCCATTTAATAGAGTCAATTGGAATTTTTAGAGCATA
ATCTTTATGGATCCTCAAAGCTGACTTTGCCAAAGGGATTGAGACCCTTACTACCATCAAATCTCTGTCTCTGCTTGGTTAAAAATTGGC
TCACTATTGCTTTGTAGTAACCCCTGCCCAGGTATTTTTTCACTTGTGAAAATAATTTGAGAAAGACCTTTGTTCCTAGCCTGTTGGGAA
AAGTTTATAATTTTATGAAAATTAAGTACAGAGGCTGCGATCTTAGAAATAATGAAGGTGCCATTTGGCTGCTCCTTAATAGTGCAGACA
GAAAACTGCAGTGAACACATGCCAAAACATGATTGAAGCCTTTGGCTGAAACTTTATACATAGAAATAATGATTTGCTCATAACAGGTAT
CATTAACTGCCACTTTTTATGTTTTCCCTAGAATTTGTAGCCTTGCTGCTTGCTTTTCTTCTGGGTGGCAAAGTTACTACTGGAAAAACA
CTATAAGTACAAAGTTTTTGGGGTTTTATCTTTGCTTTAGAAGTGGATGTGTACTTCACCTCTTGGCTGTGGAGGAACTTAGTTGCCAGG
AAATTTTTTTTTTTTTTTTCAGACGGAGTTTCGCTCTTGTTGCCCAGGCTGGGAGGGCAATGGCACCGTCTTGGCTCACTGCAACCTCCG
CCTCCCGGGTTCCAGCGATTCTCCTGCCTCAGCCTTCCGAGTAGCTGGGATTACAGGCTCCTGCCACCACGCCTGGCTAGGAAATTTTTT
GTTGTTAATATGACATTTGGATTAATCTCCAGCTTCAACAGTACTTCTTTTGTCCATAAATCTCAGGAATGTTTTAGGCAGAAAACTGGT
TTTACCCTGTTGATAATCAGAAGGAGTGTGCTTTAGGATTTATTGCATAATACTATTCTTTAATTGCAATCCTAGGTATCTATAGCATGA
GTGGCCTTAGTGAGTTTGTTGAAGTGCACATGTTTTTCAAGAGTAAAATTTAAGATTAAAAATATATCCTATATATAGATATCTAGAAAA
CTTGGTTTGTGGTGCACAGTTAAGTGTTGGATCACTAAATAACCATTGCAGGTACCGTTTGTGTAACATTACTCATTTCTGTATATTCCT
TTTATGGGAAGATATTTTGCCATGGTAACTAAAACTTTTCAGTTCTACTTTTATGATGTGAATGAATGCTACGTTTTATTAAATATTACC
AGGTCAGTACTATTTTTATACTTTATTAAGCAACAGGGGATTTTAGTTTAATAGGCTCAAAATAAAAAGTTCTTAATGGAACAGTTAAAA
ACAAAACACTAACAATCTTTACGTGAAAATCCCCACTAATAGTGCCACAATAATTTCTATAGAAATATCTAAGGTCATTAAATAGATTTT
TGAAGACGGTTCTTCATTGTGTCAGGATGACCTTTCATATCATTCTCACCAACTTGTAGTGCCCACCGTTATTTGTAACTATTAAACCAT
ACTAAGTATGTTTGTAACCAGCATTGTGATATATTCTGTACTTGTATTGCTAAAAATGAATTATTGACCTAATAAATATAGTGTTCCTGC

>33239_33239_2_GLG1-APPBP2_GLG1_chr16_74495991_ENST00000422840_APPBP2_chr17_58538148_ENST00000083182_length(amino acids)=1285AA_BP=1012
MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQQQQQQQQQQPQPPQP
PFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTTDPKFESVAREVC
KSTITEIKECADEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIFSDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCL
EKGLVKEAEEREPKIQVSELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQK
LIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEH
HCSGLHRKGRTLHCLMKVVRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVE
DCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSEFMPQGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVK
LDPALQDKCLIDLGKWCSEKTETGQELECLQDHLDDLVVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMEC
LIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRRQLRVEEL
EMTEDIRLEPDLYEACKSDIKNFCSAVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTM
LQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPMLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRI
IIQESALDYRLDPQLQLHCSDEAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKR
VKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEV
ALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDV

--------------------------------------------------------------
>33239_33239_3_GLG1-APPBP2_GLG1_chr16_74495991_ENST00000447066_APPBP2_chr17_58538148_ENST00000083182_length(transcript)=8265nt_BP=3021nt
GCTCGCCGCGGACTCAAGATGGCGGCGTGTGGACGTGTACGGAGGATGTTCCGCTTGTCGGCGGCGCTGCATCTGCTGCTGCTATTCGCG
GCCGGGGCCGAGAAACTCCCCGGCCAGGGCGTCCACAGCCAGGGCCAGGGTCCCGGGGCCAACTTTGTGTCCTTCGTAGGGCAGGCCGGA
GGCGGCGGCCCGGCGGGTCAGCAGCTGCCCCAGCTGCCTCAGTCATCGCAGCTTCAGCAGCAACAGCAGCAGCAGCAACAGCAACAGCAG
CCTCAGCCGCCGCAGCCGCCTTTCCCGGCGGGTGGGCCTCCGGCCCGGCGGGGAGGAGCGGGGGCTGGTGGGGGCTGGAAGCTGGCGGAG
GAAGAGTCCTGCAGGGAGGACGTGACCCGCGTGTGCCCTAAGCACACCTGGAGCAACAACCTGGCGGTGCTCGAGTGCCTGCAGGATGTG
AGGGAGTTGTTGTGGAATTATAAGCTGAACCTAACTACAGATCCCAAATTTGAATCTGTGGCCAGAGAGGTTTGCAAATCTACTATAACA
GAGATTAAAGAATGTGCTGATGAACCGGTTGGAAAAGGTTACATGGTTTCCTGCTTGGTGGATCACCGAGGCAACATCACTGAGTATCAG
TGTCACCAGTACATTACCAAGATGACGGCCATCATTTTTAGTGATTACCGTTTAATCTGTGGCTTCATGGATGACTGCAAAAATGACATC
AACATTCTGAAATGTGGCAGTATTCGGCTTGGAGAAAAGGATGCACATTCACAAGGTGAGGTGGTATCATGCTTGGAGAAAGGCCTGGTG
AAAGAAGCAGAAGAAAGAGAACCCAAGATTCAAGTTTCTGAACTCTGCAAGAAAGCCATTCTCCGGGTGGCTGAGCTGTCATCGGATGAC
TTTCACTTAGACCGGCATTTATATTTTGCTTGCCGAGATGATCGGGAGCGTTTTTGTGAAAATACACAAGCTGGTGAGGGCAGAGTGTAT
AAGTGCCTCTTTAACCATAAATTTGAAGAATCCATGAGTGAAAAGTGTCGAGAAGCACTTACAACCCGCCAAAAGCTGATTGCCCAGGAT
TATAAAGTCAGTTATTCATTGGCCAAATCCTGTAAAAGTGACTTGAAGAAATACCGGTGCAATGTGGAAAACCTTCCGCGATCGCGTGAA
GCCAGGCTCTCCTACTTGTTAATGTGCCTGGAGTCAGCTGTACACAGAGGGCGACAAGTCAGCAGTGAGTGCCAGGGGGAGATGCTGGAT
TACCGACGCATGTTGATGGAAGACTTTTCTCTGAGCCCTGAGATCATCCTAAGCTGTCGGGGGGAGATTGAACACCATTGTTCCGGATTA
CATCGAAAAGGGCGGACCCTACACTGTCTGATGAAAGTAGTTCGAGGGGAGAAGGGGAACCTTGGAATGAACTGCCAGCAGGCGCTTCAA
ACACTGATTCAGGAGACTGACCCTGGTGCAGATTACCGCATTGATCGAGCTTTGAATGAAGCTTGTGAATCTGTAATCCAGACAGCCTGC
AAACATATAAGATCTGGAGACCCAATGATCTTGTCGTGCCTGATGGAACATTTATACACAGAGAAGATGGTAGAAGACTGTGAACACCGT
CTCTTAGAGCTGCAGTATTTCATCTCCCGGGATTGGAAGCTGGACCCTGTCCTGTACCGCAAGTGCCAGGGAGACGCTTCTCGTCTTTGC
CACACCCACGGTTGGAATGAGACCAGTGAATTTATGCCTCAGGGAGCTGTGTTCTCTTGTTTATACAGACACGCCTACCGCACTGAGGAA
CAGGGAAGGAGGCTCTCACGGGAGTGCCGAGCTGAAGTCCAAAGGATCCTACACCAGCGTGCCATGGATGTCAAGCTGGATCCTGCCCTC
CAGGATAAGTGCCTGATTGATCTGGGAAAATGGTGCAGTGAGAAAACAGAGACTGGACAGGAGCTGGAGTGCCTTCAGGACCATCTGGAT
GACTTGGTGGTGGAGTGTAGAGATATAGTTGGCAACCTCACTGAGTTAGAATCAGAGGATATTCAAATAGAAGCCTTGCTGATGAGAGCC
TGTGAGCCCATAATTCAGAACTTCTGCCACGATGTGGCAGATAACCAGATAGACTCTGGGGACCTGATGGAGTGTCTGATACAGAACAAA
CACCAGAAGGACATGAACGAGAAGTGTGCCATCGGAGTTACCCACTTCCAGCTGGTGCAGATGAAGGATTTTCGGTTTTCTTACAAGTTT
AAAATGGCCTGCAAGGAGGACGTGTTGAAGCTTTGCCCAAACATAAAAAAGAAGGTGGACGTGGTGATCTGCCTGAGCACGACCGTGCGC
AATGACACTCTGCAGGAAGCCAAGGAGCACAGGGTGTCCCTGAAGTGCCGCAGGCAGCTCCGTGTGGAGGAGCTGGAGATGACGGAGGAC
ATCCGCTTGGAGCCAGATCTATACGAAGCCTGCAAGAGTGACATCAAAAACTTCTGTTCCGCTGTGCAATATGGCAACGCTCAGATTATC
GAATGTCTGAAAGAAAACAAGAAGCAGCTAAGCACCCGCTGCCACCAAAAAGTATTTAAGCTGCAGGAGACAGAGATGATGGACCCAGAG
CTAGACTACACCCTCATGAGGGTCTGCAAGCAGATGATAAAGAGGTTCTGTCCGGAAGCAGATTCTAAAACCATGTTGCAGTGCTTGAAG
CAAAATAAAAACAGTGAATTGATGGATCCCAAATGCAAACAGATGATAACCAAGCGCCAGATCACCCAGAACACAGATTACCGCTTAAAC
CCCATGTTAAGAAAAGCCTGTAAAGCTGACATTCCTAAATTCTGTCACGGTATCCTGACTAAGGCCAAGGATGATTCAGAATTAGAAGGA
CAAGTCATCTCTTGCCTGAAGCTGAGATATGCTGACCAGCGCCTGTCTTCAGACTGTGAAGACCAGATCCGAATCATTATCCAGGAGTCC
GCCCTGGACTACCGCCTGGATCCTCAGCTCCAGCTGCACTGCTCAGACGAGGCAGCCCTTGACATTAGACAGTCAGTGTTTGGTGGCAAA
AATATCCACGTAGCAACAGCTCATGAAGATTTGGCCTACTCTTCTTATGTCCACCAGTATAGCTCTGGGAAATTTGACAATGCACTATTT
CATGCAGAAAGAGCTATTGGTATCATTACCCACATCCTACCTGAAGATCATCTTCTTTTGGCTTCTTCAAAGAGGGTGAAAGCACTTATT
TTAGAGGAGATTGCAATTGATTGTCATAATAAGGAAACTGAACAGAGGCTGCTTCAAGAAGCTCATGATTTGCACCTGTCTTCACTCCAA
CTAGCTAAAAAAGCTTTTGGGGAATTTAATGTACAGACTGCAAAACACTATGGAAACCTTGGAAGACTTTATCAGTCAATGAGAAAATTT
AAGGAAGCTGAAGAAATGCACATCAAAGCAATTCAGATTAAAGAACAACTTCTTGGTCAAGAAGATTATGAAGTAGCCCTTTCAGTGGGA
CATCTGGCTTCTTTATATAATTATGACATGAATCAGTATGAAAATGCTGAGAAACTTTATTTGCGATCTATAGCAATTGGGAAGAAACTT
TTTGGTGAGGGCTACAGTGGACTAGAATATGATTATCGAGGTCTCATTAAACTTTACAACTCCATTGGAAATTACGAGAAAGTGTTTGAA
TATCACAATGTTCTGTCTAACTGGAACCGGTTGCGAGATCGGCAATATTCAGTGACAGATGCTCTTGAAGATGTCAGCACCAGCCCCCAG
TCCACTGAAGAAGTGGTGCAGTCCTTCCTGATTTCTCAGAATGTCGAGGGACCGAGCTGCTGAGGGAGGACCTCAGTTAACCAATTACCT
TTTCCCGGATTCCAGGGAATTCATACTGTGAAATCAAAACCATGTTGTTTTGGGGGGCTGGAATTTGCATTGAAACACTGGTCCAGTCCA
TTGAAGACCCTATTTTGGGTGATCCCTATCTTGCAGAATGTCTGTAGGAATAAGCATATATTCAGTTATATTCAGCATGTACCGCATGTG
TAAGTAGTCTGGCCCACATTTTCAACCTAGTAGAACAAACAACAGGAAATCTTTTTTTTGTTGTTTTTAAAAAATTCATTTTGCAGAAAG
CCTGAAAGAAAAAAAATACCCCTAAATAAAACTATTTAAGAGTTTAAAAGAGTTGCATTCTTATTATGTAAGGATGATTTTAACAACTTT
TTAATATGTAATTCTTCCATGTGGAGGTATTCAATACTGTAGTGTAAAGAAATTTTATGCGGAAAATCTTTATATGCAGTATAGAAAAGT
TAACACAAGTACTAATAAAAGAGGGACATCCCGACTTACGTTTTTCTACCTTGCCCAGATAAGTGGATACAACCACTCTATATTACAAGG
AAAGGACTGTCAGATTCATCTGAACTGGACCAGTGTTGATCTGTAATGTAATAGAAAATCTGATAGACCAGCACTTCTGACTTTTTTTTT
TTTGGTACAACAATGCAAGATGCTCTGATAGCATTTGCTAACAGGACCAGGAGGATCTAAAAAGGACCAGCCTAATGTAGAAGGTGGTTA
CTTGGACCAGAGGCTTTAGATTATTATTTTAGATCCTACATATACTTTTATCAGTAGAATGATTTCATTTAGATGTATAATGAAAAAGGA
TAATGCAAAAATTATGTAATAGATACCAAATTAGGGAAGTTTGGCAATTTCAATGGCATATTTTTAGTCAAGGTACACAGATGGCAGTGC
CATAAGCAAGTCTATAAATATCGGCTGCAGCCATCCCCCTCATTTTAAATGTTGCCCTAATAATCAATGCAGTTAACAAGTATATTGGCT
GTGTGTCATGAAATAGTTCATGTTCAGATGGAAATGTTAGGTTACTGTATGGTTTATGGAGATTAATGAAAATGAATGCCCAAAAATAAG
TCTTAGAAAATCCTCCATTTTTATGGTAAATAGTAATACAACTAGGTCATTTCATTTGAAATCTAGGAGTCAAATGGAAAGATCCCCTAA
TAATACACCTATTTCACTAACTTGTCTTTCTGTTTATTGGGTTTTGATTTGATTTTTTGTAAGCCAGTCAGGTTATTTAATGATGAGGTA
ATAATCAAATTTAAGAATTTGTGACATGTAGCAATTCAAGAAACAAAAAGGTATTTTGCTGTTACCTCAATTCTTACTGTAGTAGCCCAT
CTGATGCTTCTATAGTTAAGAATCTGGGTTCCCCCCCTATTTTCAGGGGTTCATGACTTGGCTGTTAAAGATGTTGCTCCTAGCTAATGC
TTGGAGTAGTCTGTGGGTGAATGGATGTGTGTTGAATTTTAGTTTTCTTTTAACATGCATGTTGGGTGAGAGGGGAAAAAAATCTAAGCT
GTCTGCCACATTGAGTACAGAAAAGTTGTAGATTTCAAATTTTATTAATATTTTAAGCACTTTTTTGAACTTCCCAACCTTGTTTGAAGC
TGTTATTTGCAGTCCTATTAGTTTTGAGCCATTGCATTTAAGTTCCCTAGGAGGGGGTTGGTTGGGGGATGTACTGAAAGAGATGAAGCA
AACCCACACCCTAAGATGGTAACTGTGTGATTTAGAAACCTGAGTTTACTCCTCAAATCGAATTATTTTCTTTTTAAATTTTGGAAAGAG
TAAATTGACGTACTTGCAGTTTATGAAGCTGCCCCCCACCCCTCAGTTAATTGCAGTCTAATGTCAAGAGGCACTTCTTTATTAATTACC
AAATAGTCTTTGTGACCAAGGACTAACATTTTTAAGTTACTCAGCTCTATCCTCATGGGCCTATATATTTAATACCTCCAAAGATATTTT
CAGGATAGGCTTTGTATACTTTTATTGGTTATTTAGAATCCAGTGGTATGTTTGTGGTATAGGAATGTCATGGTAAATTGTTTTTCAATA
AATATTTTGAAACATGTTTCCATATGAAGTTTTTTTTTCAATCTGTATTTTTTGGTTTTGTGCACATACAGCATTTCCTAGGATAAAAAT
AAACAAATGACTTACAGCCTCATCCTCCCTAACTCCATTTGAACTCAACTTAGCTCACACTCAGTGATAAAACAACATGGTATGTAGAAG
CCTAGGATCACAGGGTGATAATGTCAATTGGCAGCCAGTTGTGTTTTTTTGAAACATCATTATTGGCAGTTTCTCCTTATCACCACTGCT
TTAATGTAGTTTTTTTGTAAATCCATATACTTTAATGCATACACTCTAGCTTAAGAAAACATTGCCATTTTGGTTAGGGATATGACTTAA
TGTGCTATTATTTCTGGTTCTAATGAAGAATAATACCCTATGACTTTAAGTGTAAGATTCATCCTTTAAGTAGGGATGTTTAGGATAAGT
TAGATGTGTGCCACTATGATTTATTGGGTTTCTTAAAAATCTTGAAGAAAATAATAAAATTTATCTCACAATAAGTTAACTTGCGCAAAC
TTTTTACATATGGTGAGGTGCGTAAGGAAGCCCTGGCCAACTTAAAGATTTTTCTGGAGGTTCAGCAAAGTTATGTTAAATTAGGGGCCT
TTGGTCTCATCCTTCTCTGACTCTTCTACCCAGTCTTTTCCTAAAGTTCGGTGCTACTCCAGTTGGGTGCATCAGGGAGCTCCGTCAGCA
CTCGCATGTGTCGCTCAGGTGGCCACTCATGCCTGCATTCCATTTAATAGAGTCAATTGGAATTTTTAGAGCATAATCTTTATGGATCCT
CAAAGCTGACTTTGCCAAAGGGATTGAGACCCTTACTACCATCAAATCTCTGTCTCTGCTTGGTTAAAAATTGGCTCACTATTGCTTTGT
AGTAACCCCTGCCCAGGTATTTTTTCACTTGTGAAAATAATTTGAGAAAGACCTTTGTTCCTAGCCTGTTGGGAAAAGTTTATAATTTTA
TGAAAATTAAGTACAGAGGCTGCGATCTTAGAAATAATGAAGGTGCCATTTGGCTGCTCCTTAATAGTGCAGACAGAAAACTGCAGTGAA
CACATGCCAAAACATGATTGAAGCCTTTGGCTGAAACTTTATACATAGAAATAATGATTTGCTCATAACAGGTATCATTAACTGCCACTT
TTTATGTTTTCCCTAGAATTTGTAGCCTTGCTGCTTGCTTTTCTTCTGGGTGGCAAAGTTACTACTGGAAAAACACTATAAGTACAAAGT
TTTTGGGGTTTTATCTTTGCTTTAGAAGTGGATGTGTACTTCACCTCTTGGCTGTGGAGGAACTTAGTTGCCAGGAAATTTTTTTTTTTT
TTTTCAGACGGAGTTTCGCTCTTGTTGCCCAGGCTGGGAGGGCAATGGCACCGTCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCCAG
CGATTCTCCTGCCTCAGCCTTCCGAGTAGCTGGGATTACAGGCTCCTGCCACCACGCCTGGCTAGGAAATTTTTTGTTGTTAATATGACA
TTTGGATTAATCTCCAGCTTCAACAGTACTTCTTTTGTCCATAAATCTCAGGAATGTTTTAGGCAGAAAACTGGTTTTACCCTGTTGATA
ATCAGAAGGAGTGTGCTTTAGGATTTATTGCATAATACTATTCTTTAATTGCAATCCTAGGTATCTATAGCATGAGTGGCCTTAGTGAGT
TTGTTGAAGTGCACATGTTTTTCAAGAGTAAAATTTAAGATTAAAAATATATCCTATATATAGATATCTAGAAAACTTGGTTTGTGGTGC
ACAGTTAAGTGTTGGATCACTAAATAACCATTGCAGGTACCGTTTGTGTAACATTACTCATTTCTGTATATTCCTTTTATGGGAAGATAT
TTTGCCATGGTAACTAAAACTTTTCAGTTCTACTTTTATGATGTGAATGAATGCTACGTTTTATTAAATATTACCAGGTCAGTACTATTT
TTATACTTTATTAAGCAACAGGGGATTTTAGTTTAATAGGCTCAAAATAAAAAGTTCTTAATGGAACAGTTAAAAACAAAACACTAACAA
TCTTTACGTGAAAATCCCCACTAATAGTGCCACAATAATTTCTATAGAAATATCTAAGGTCATTAAATAGATTTTTGAAGACGGTTCTTC
ATTGTGTCAGGATGACCTTTCATATCATTCTCACCAACTTGTAGTGCCCACCGTTATTTGTAACTATTAAACCATACTAAGTATGTTTGT

>33239_33239_3_GLG1-APPBP2_GLG1_chr16_74495991_ENST00000447066_APPBP2_chr17_58538148_ENST00000083182_length(amino acids)=1274AA_BP=1001
MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQQQQQQQQQQPQPPQP
PFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVRELLWNYKLNLTTDPKFESVAREVCKSTITEIKECA
DEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIFSDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEER
EPKIQVSELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQKLIAQDYKVSYS
LAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRT
LHCLMKVVRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVEDCEHRLLELQY
FISRDWKLDPVLYRKCQGDASRLCHTHGWNETSEFMPQGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLI
DLGKWCSEKTETGQELECLQDHLDDLVVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMECLIQNKHQKDMN
EKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRRQLRVEELEMTEDIRLEPD
LYEACKSDIKNFCSAVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTMLQCLKQNKNSE
LMDPKCKQMITKRQITQNTDYRLNPMLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRL
DPQLQLHCSDEAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAI
DCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLY
NYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GLG1-APPBP2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for GLG1-APPBP2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for GLG1-APPBP2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source