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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:GLG1-BCAR1 (FusionGDB2 ID:33240)

Fusion Gene Summary for GLG1-BCAR1

check button Fusion gene summary
Fusion gene informationFusion gene name: GLG1-BCAR1
Fusion gene ID: 33240
HgeneTgene
Gene symbol

GLG1

BCAR1

Gene ID

2734

9564

Gene namegolgi glycoprotein 1BCAR1 scaffold protein, Cas family member
SynonymsCFR-1|ESL-1|MG-160|MG160CAS|CAS1|CASS1|CRKAS|P130Cas
Cytomap

16q23.1

16q23.1

Type of geneprotein-codingprotein-coding
DescriptionGolgi apparatus protein 1E-selectin ligand 1cysteine-rich fibroblast growth factor receptorgolgi sialoglycoprotein MG-160breast cancer anti-estrogen resistance protein 1BCAR1, Cas family scaffold proteinBCAR1, Cas family scaffolding proteinCas scaffolding protein family member 1Crk-associated substrate p130Cas
Modification date2020031320200327
UniProtAcc

Q92896

P56945

Ensembl transtripts involved in fusion geneENST00000205061, ENST00000422840, 
ENST00000447066, 		ENST00000546196, 
ENST00000393420, ENST00000393422, 
ENST00000418647, ENST00000420641, 
ENST00000535626, ENST00000538440, 
ENST00000542031, ENST00000566982, 
ENST00000162330, 
Fusion gene scores* DoF score23 X 21 X 12=57966 X 4 X 4=96
# samples 296
** MAII scorelog2(29/5796*10)=-4.320932789542
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/96*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GLG1 [Title/Abstract] AND BCAR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGLG1(74640555)-BCAR1(75276988), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBCAR1

GO:0007015

actin filament organization

16105984

TgeneBCAR1

GO:0007229

integrin-mediated signaling pathway

8649368

TgeneBCAR1

GO:0010595

positive regulation of endothelial cell migration

21245381

TgeneBCAR1

GO:0016477

cell migration

9425168

TgeneBCAR1

GO:0030335

positive regulation of cell migration

9472046

TgeneBCAR1

GO:0050851

antigen receptor-mediated signaling pathway

10587647

TgeneBCAR1

GO:0050853

B cell receptor signaling pathway

9020138

TgeneBCAR1

GO:0086100

endothelin receptor signaling pathway

19086031


check buttonFusion gene breakpoints across GLG1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BCAR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-YJ-A8SW-01AGLG1chr16

74640555

-BCAR1chr16

75276988

-


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Fusion Gene ORF analysis for GLG1-BCAR1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000205061ENST00000546196GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-5UTRENST00000422840ENST00000546196GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-5UTRENST00000447066ENST00000546196GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000393420GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000393422GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000418647GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000420641GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000535626GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000538440GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000542031GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000205061ENST00000566982GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000393420GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000393422GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000418647GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000420641GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000535626GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000538440GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000542031GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000422840ENST00000566982GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000393420GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000393422GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000418647GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000420641GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000535626GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000538440GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000542031GLG1chr16

74640555

-BCAR1chr16

75276988

-
5CDS-intronENST00000447066ENST00000566982GLG1chr16

74640555

-BCAR1chr16

75276988

-
In-frameENST00000205061ENST00000162330GLG1chr16

74640555

-BCAR1chr16

75276988

-
In-frameENST00000422840ENST00000162330GLG1chr16

74640555

-BCAR1chr16

75276988

-
In-frameENST00000447066ENST00000162330GLG1chr16

74640555

-BCAR1chr16

75276988

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000205061GLG1chr1674640555-ENST00000162330BCAR1chr1675276988-35404582030581012
ENST00000422840GLG1chr1674640555-ENST00000162330BCAR1chr1675276988-3520438030381012
ENST00000447066GLG1chr1674640555-ENST00000162330BCAR1chr1675276988-35384561830561012

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000205061ENST00000162330GLG1chr1674640555-BCAR1chr1675276988-0.0030762440.99692374
ENST00000422840ENST00000162330GLG1chr1674640555-BCAR1chr1675276988-0.0028620950.9971379
ENST00000447066ENST00000162330GLG1chr1674640555-BCAR1chr1675276988-0.0030492390.99695075

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Fusion Genomic Features for GLG1-BCAR1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for GLG1-BCAR1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:74640555/chr16:75276988)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GLG1

Q92896

BCAR1

P56945

FUNCTION: Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). {ECO:0000269|PubMed:8985126}.FUNCTION: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (PubMed:12832404, PubMed:12432078). Implicated in induction of cell migration and cell branching (PubMed:12432078, PubMed:12832404, PubMed:17038317). Involved in the BCAR3-mediated inhibition of TGFB signaling (By similarity). {ECO:0000250|UniProtKB:Q61140, ECO:0000269|PubMed:12432078, ECO:0000269|PubMed:12832404, ECO:0000269|PubMed:17038317}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-12754_571461204.0Compositional biasNote=Poly-Gly
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-12771_861461204.0Compositional biasNote=Poly-Gln
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-12654_571461180.0Compositional biasNote=Poly-Gly
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-12671_861461180.0Compositional biasNote=Poly-Gln
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-12654_571461193.0Compositional biasNote=Poly-Gly
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-12671_861461193.0Compositional biasNote=Poly-Gln
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127116_1491461204.0RepeatNote=Cys-rich GLG1 1
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126116_1491461180.0RepeatNote=Cys-rich GLG1 1
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126116_1491461193.0RepeatNote=Cys-rich GLG1 1
TgeneBCAR1chr16:74640555chr16:75276988ENST0000016233007422_6144871.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000001623300774_874871.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342007422_6144889.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000003934200774_874889.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342207422_61422889.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000003934220774_8722889.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST0000041864718422_61450917.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000004186471874_8750917.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST0000042064107422_61422889.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000004206410774_8722889.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053562618422_6144723.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000005356261874_874723.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053844007422_6144871.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000005384400774_874871.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST0000054203107422_6142869.0Compositional biasNote=Ser-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST000005420310774_872869.0Compositional biasNote=Pro-rich
TgeneBCAR1chr16:74640555chr16:75276988ENST00000162330073_654871.0DomainSH3
TgeneBCAR1chr16:74640555chr16:75276988ENST00000393420073_654889.0DomainSH3
TgeneBCAR1chr16:74640555chr16:75276988ENST00000535626183_654723.0DomainSH3
TgeneBCAR1chr16:74640555chr16:75276988ENST00000538440073_654871.0DomainSH3
TgeneBCAR1chr16:74640555chr16:75276988ENST00000542031073_652869.0DomainSH3
TgeneBCAR1chr16:74640555chr16:75276988ENST0000016233007635_6434871.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342007635_6434889.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342207635_64322889.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000041864718635_64350917.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000042064107635_64322889.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053562618635_6434723.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053844007635_6434871.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000054203107635_6432869.0MotifSH3-binding
TgeneBCAR1chr16:74640555chr16:75276988ENST0000016233007115_4164871.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000016233007746_7964871.0RegionNote=Divergent helix-loop-helix motif
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342007115_4164889.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342007746_7964889.0RegionNote=Divergent helix-loop-helix motif
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342207115_41622889.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000039342207746_79622889.0RegionNote=Divergent helix-loop-helix motif
TgeneBCAR1chr16:74640555chr16:75276988ENST0000041864718115_41650917.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000041864718746_79650917.0RegionNote=Divergent helix-loop-helix motif
TgeneBCAR1chr16:74640555chr16:75276988ENST0000042064107115_41622889.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000042064107746_79622889.0RegionNote=Divergent helix-loop-helix motif
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053562618115_4164723.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053562618746_7964723.0RegionNote=Divergent helix-loop-helix motif
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053844007115_4164871.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000053844007746_7964871.0RegionNote=Divergent helix-loop-helix motif
TgeneBCAR1chr16:74640555chr16:75276988ENST0000054203107115_4162869.0RegionSubstrate for kinases
TgeneBCAR1chr16:74640555chr16:75276988ENST0000054203107746_7962869.0RegionNote=Divergent helix-loop-helix motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-1271041_11011461204.0RepeatNote=Cys-rich GLG1 16
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127150_2121461204.0RepeatNote=Cys-rich GLG1 2
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127215_2781461204.0RepeatNote=Cys-rich GLG1 3
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127286_3461461204.0RepeatNote=Cys-rich GLG1 4
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127347_4131461204.0RepeatNote=Cys-rich GLG1 5
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127414_4731461204.0RepeatNote=Cys-rich GLG1 6
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127475_5371461204.0RepeatNote=Cys-rich GLG1 7
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127538_6041461204.0RepeatNote=Cys-rich GLG1 8
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127609_6681461204.0RepeatNote=Cys-rich GLG1 9
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127670_7281461204.0RepeatNote=Cys-rich GLG1 10
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127729_7881461204.0RepeatNote=Cys-rich GLG1 11
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127796_8561461204.0RepeatNote=Cys-rich GLG1 12
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127858_9111461204.0RepeatNote=Cys-rich GLG1 13
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127912_9791461204.0RepeatNote=Cys-rich GLG1 14
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-127980_10351461204.0RepeatNote=Cys-rich GLG1 15
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-1261041_11011461180.0RepeatNote=Cys-rich GLG1 16
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126150_2121461180.0RepeatNote=Cys-rich GLG1 2
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126215_2781461180.0RepeatNote=Cys-rich GLG1 3
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126286_3461461180.0RepeatNote=Cys-rich GLG1 4
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126347_4131461180.0RepeatNote=Cys-rich GLG1 5
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126414_4731461180.0RepeatNote=Cys-rich GLG1 6
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126475_5371461180.0RepeatNote=Cys-rich GLG1 7
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126538_6041461180.0RepeatNote=Cys-rich GLG1 8
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126609_6681461180.0RepeatNote=Cys-rich GLG1 9
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126670_7281461180.0RepeatNote=Cys-rich GLG1 10
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126729_7881461180.0RepeatNote=Cys-rich GLG1 11
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126796_8561461180.0RepeatNote=Cys-rich GLG1 12
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126858_9111461180.0RepeatNote=Cys-rich GLG1 13
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126912_9791461180.0RepeatNote=Cys-rich GLG1 14
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-126980_10351461180.0RepeatNote=Cys-rich GLG1 15
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-1261041_11011461193.0RepeatNote=Cys-rich GLG1 16
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126150_2121461193.0RepeatNote=Cys-rich GLG1 2
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126215_2781461193.0RepeatNote=Cys-rich GLG1 3
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126286_3461461193.0RepeatNote=Cys-rich GLG1 4
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126347_4131461193.0RepeatNote=Cys-rich GLG1 5
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126414_4731461193.0RepeatNote=Cys-rich GLG1 6
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126475_5371461193.0RepeatNote=Cys-rich GLG1 7
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126538_6041461193.0RepeatNote=Cys-rich GLG1 8
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126609_6681461193.0RepeatNote=Cys-rich GLG1 9
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126670_7281461193.0RepeatNote=Cys-rich GLG1 10
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126729_7881461193.0RepeatNote=Cys-rich GLG1 11
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126796_8561461193.0RepeatNote=Cys-rich GLG1 12
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126858_9111461193.0RepeatNote=Cys-rich GLG1 13
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126912_9791461193.0RepeatNote=Cys-rich GLG1 14
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-126980_10351461193.0RepeatNote=Cys-rich GLG1 15
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-1271167_11791461204.0Topological domainCytoplasmic
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-12730_11451461204.0Topological domainExtracellular
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-1261167_11791461180.0Topological domainCytoplasmic
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-12630_11451461180.0Topological domainExtracellular
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-1261167_11791461193.0Topological domainCytoplasmic
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-12630_11451461193.0Topological domainExtracellular
HgeneGLG1chr16:74640555chr16:75276988ENST00000205061-1271146_11661461204.0TransmembraneHelical
HgeneGLG1chr16:74640555chr16:75276988ENST00000422840-1261146_11661461180.0TransmembraneHelical
HgeneGLG1chr16:74640555chr16:75276988ENST00000447066-1261146_11661461193.0TransmembraneHelical
TgeneBCAR1chr16:74640555chr16:75276988ENST00000393422073_6522889.0DomainSH3
TgeneBCAR1chr16:74640555chr16:75276988ENST00000418647183_6550917.0DomainSH3
TgeneBCAR1chr16:74640555chr16:75276988ENST00000420641073_6522889.0DomainSH3


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Fusion Gene Sequence for GLG1-BCAR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33240_33240_1_GLG1-BCAR1_GLG1_chr16_74640555_ENST00000205061_BCAR1_chr16_75276988_ENST00000162330_length(transcript)=3540nt_BP=458nt
GAGCTCGCCGCGGACTCAAGATGGCGGCGTGTGGACGTGTACGGAGGATGTTCCGCTTGTCGGCGGCGCTGCATCTGCTGCTGCTATTCG
CGGCCGGGGCCGAGAAACTCCCCGGCCAGGGCGTCCACAGCCAGGGCCAGGGTCCCGGGGCCAACTTTGTGTCCTTCGTAGGGCAGGCCG
GAGGCGGCGGCCCGGCGGGTCAGCAGCTGCCCCAGCTGCCTCAGTCATCGCAGCTTCAGCAGCAACAGCAGCAGCAGCAACAGCAACAGC
AGCCTCAGCCGCCGCAGCCGCCTTTCCCGGCGGGTGGGCCTCCGGCCCGGCGGGGAGGAGCGGGGGCTGGTGGGGGCTGGAAGCTGGCGG
AGGAAGAGTCCTGCAGGGAGGACGTGACCCGCGTGTGCCCTAAGCACACCTGGAGCAACAACCTGGCGGTGCTCGAGTGCCTGCAGGATG
TGAGGGAGAACGTGCTGGCCAAAGCGCTCTATGACAATGTGGCCGAGTCCCCGGATGAGCTCTCCTTCCGCAAGGGTGACATCATGACGG
TGCTGGAGCAGGACACGCAGGGCCTGGACGGCTGGTGGCTCTGCTCGCTGCATGGGCGCCAGGGCATCGTGCCTGGGAACCGCCTCAAGA
TCTTGGTGGGCATGTATGATAAGAAGCCAGCAGGGCCTGGCCCCGGCCCTCCCGCCACCCCGGCCCAGCCTCAGCCTGGCCTCCATGCCC
CAGCGCCTCCGGCCTCCCAGTACACGCCCATGCTCCCCAACACCTACCAGCCCCAGCCAGACAGCGTCTACCTGGTGCCCACTCCCAGCA
AGGCTCAGCAAGGCCTCTACCAAGTCCCGGGTCCCAGCCCTCAGTTCCAGTCTCCCCCAGCCAAGCAGACATCCACCTTCTCGAAGCAGA
CACCCCATCACCCGTTTCCCAGCCCGGCCACAGACCTGTACCAGGTGCCCCCAGGGCCTGGAGGCCCTGCCCAGGATATTTACCAGGTGC
CACCTTCTGCCGGGATGGGGCATGACATCTACCAGGTCCCCCCGTCCATGGACACACGCAGCTGGGAGGGCACGAAGCCCCCGGCAAAGG
TGGTGGTGCCCACCCGCGTGGGGCAGGGCTATGTATACGAGGCCGCCCAGCCGGAGCAGGACGAGTACGACATCCCGCGACACCTGCTGG
CCCCGGGGCCACAGGACATCTATGATGTGCCCCCGGTTCGGGGGCTGCTTCCCAGCCAGTATGGCCAGGAGGTGTATGACACACCCCCCA
TGGCTGTCAAGGGTCCCAATGGCCGAGACCCGTTGCTGGAGGTGTATGACGTGCCCCCCAGTGTGGAGAAGGGCCTGCCACCGTCCAACC
ACCACGCAGTCTACGACGTTCCTCCATCGGTGAGCAAGGATGTGCCCGATGGCCCACTGCTGCGTGAGGAGACCTACGATGTGCCCCCCG
CCTTCGCCAAGGCCAAGCCCTTTGACCCGGCCCGCACCCCACTGGTACTGGCTGCGCCCCCTCCAGACTCCCCGCCGGCCGAGGACGTGT
ATGACGTGCCGCCCCCGGCTCCTGACCTCTACGACGTGCCCCCTGGCTTGCGGCGGCCTGGCCCGGGCACCCTGTACGATGTGCCCCGTG
AACGGGTGCTTCCTCCTGAGGTGGCTGATGGTGGCGTGGTCGACAGTGGTGTGTATGCGGTGCCTCCCCCAGCTGAACGTGAAGCCCCGG
CAGAGGGCAAGCGCCTGTCGGCCTCCAGCACCGGCAGCACACGCAGCAGCCAGTCTGCGTCCTCCTTGGAGGTGGCAGGGCCGGGCCGGG
AACCCCTGGAGCTGGAAGTTGCTGTGGAGGCCCTGGCACGGCTGCAGCAGGGTGTGAGCGCCACCGTTGCCCACCTTCTGGACCTGGCAG
GCAGCGCCGGTGCGACTGGGAGCTGGCGTAGCCCCTCTGAGCCACAGGAGCCGCTGGTGCAGGACCTGCAGGCTGCTGTGGCCGCTGTCC
AGAGTGCCGTCCACGAGCTGTTGGAGTTTGCCCGCAGCGCGGTGGGCAATGCTGCCCACACATCTGACCGTGCCCTGCATGCCAAGCTTA
GCCGGCAGCTGCAGAAGATGGAGGACGTGCACCAGACGCTGGTGGCACATGGTCAGGCCCTCGACGCTGGCCGGGGAGGCTCTGGAGCCA
CCCTTGAGGACCTGGACCGGCTGGTGGCCTGCTCGCGGGCTGTGCCCGAGGACGCCAAGCAGCTGGCCTCCTTCCTGCACGGCAATGCCT
CACTGCTCTTCAGACGGACCAAGGCCACTGCCCCGGGGCCTGAGGGGGGTGGCACCCTGCACCCCAACCCCACTGACAAGACCAGCAGCA
TCCAGTCACGACCCCTGCCCTCACCCCCTAAGTTCACCTCCCAGGACTCGCCAGATGGGCAGTACGAGAACAGCGAGGGGGGCTGGATGG
AGGACTATGACTACGTCCACCTACAGGGGAAGGAGGAGTTTGAGAAGACCCAGAAGGAGCTGCTGGAAAAGGGCAGCATCACGCGGCAGG
GCAAGAGCCAGCTGGAGTTGCAGCAGCTGAAGCAGTTTGAACGACTGGAACAGGAGGTGTCACGGCCCATAGACCACGACCTGGCCAACT
GGACGCCAGCCCAACCCCTGGCCCCGGGGCGAACAGGCGGCCTGGGGCCCTCGGACCGGCAGCTGCTGCTCTTCTACCTGGAGCAGTGTG
AGGCCAACCTGACCACACTGACCAACGCCGTGGACGCCTTCTTTACCGCCGTGGCCACCAACCAGCCGCCCAAGATCTTTGTGGCGCACA
GCAAGTTCGTCATCCTCAGCGCCCACAAGCTGGTGTTCATCGGGGACACACTGTCACGGCAGGCCAAGGCTGCTGACGTGCGCAGCCAGG
TGACCCACTACAGCAACCTGCTGTGCGACCTCCTGCGCGGCATCGTGGCCACCACCAAGGCCGCTGCCTTGCAGTACCCATCGCCTTCCG
CGGCCCAGGACATGGTGGAGAGGGTCAAGGAGCTGGGCCACAGCACCCAGCAGTTCCGCCGCGTCCTAGGCCAGCTGGCAGCCGCCTGAG
GGTGGTGACCCCAGGAGGGAGGCAGGGGAGGGGTGCGGCGGTCCCAGCTCCCTGGCTCCCATGTCAAGAGTCGCTGTGCCACAGGCTTAG
GGACAGGACCCCAGCTCTGCGTCGGTCCTGGTGCCCTGGATGCCCAGGAATCTGTATATATTTATGGCCGGGCAGGGTGTGGGGCCATGC
CTCCTCAGGAGCCGAAGCCCAGGGGCCGGCCAGTGGCCTTCCCCAGCATGCACCACGGGCCCGGGTTGGGTCACCAGACGGGGCTGGAGT
GTGAGGGTCCTGCAGCCTGCAGGACCTCGTGCCACCCCGAGGGCTGAGCCTGGTCCCACGAGGGTGCCGTGTCCCCTGACAGGGCCAGTG
CAGTTTGGTGTGTCCTCCGCCTTACCAGGAGAAGAACCTGAAGAACTATTTTTCGTTATTGGTTTTCCAATCATTTGACTAAGAGTCTCC

>33240_33240_1_GLG1-BCAR1_GLG1_chr16_74640555_ENST00000205061_BCAR1_chr16_75276988_ENST00000162330_length(amino acids)=1012AA_BP=146
MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQQQQQQQQQQPQPPQP
PFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVRENVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQ
GLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLY
QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRV
GQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDV
PPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPE
VADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATG
SWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDR
LVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVH
LQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTL
TNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVE

--------------------------------------------------------------
>33240_33240_2_GLG1-BCAR1_GLG1_chr16_74640555_ENST00000422840_BCAR1_chr16_75276988_ENST00000162330_length(transcript)=3520nt_BP=438nt
ATGGCGGCGTGTGGACGTGTACGGAGGATGTTCCGCTTGTCGGCGGCGCTGCATCTGCTGCTGCTATTCGCGGCCGGGGCCGAGAAACTC
CCCGGCCAGGGCGTCCACAGCCAGGGCCAGGGTCCCGGGGCCAACTTTGTGTCCTTCGTAGGGCAGGCCGGAGGCGGCGGCCCGGCGGGT
CAGCAGCTGCCCCAGCTGCCTCAGTCATCGCAGCTTCAGCAGCAACAGCAGCAGCAGCAACAGCAACAGCAGCCTCAGCCGCCGCAGCCG
CCTTTCCCGGCGGGTGGGCCTCCGGCCCGGCGGGGAGGAGCGGGGGCTGGTGGGGGCTGGAAGCTGGCGGAGGAAGAGTCCTGCAGGGAG
GACGTGACCCGCGTGTGCCCTAAGCACACCTGGAGCAACAACCTGGCGGTGCTCGAGTGCCTGCAGGATGTGAGGGAGAACGTGCTGGCC
AAAGCGCTCTATGACAATGTGGCCGAGTCCCCGGATGAGCTCTCCTTCCGCAAGGGTGACATCATGACGGTGCTGGAGCAGGACACGCAG
GGCCTGGACGGCTGGTGGCTCTGCTCGCTGCATGGGCGCCAGGGCATCGTGCCTGGGAACCGCCTCAAGATCTTGGTGGGCATGTATGAT
AAGAAGCCAGCAGGGCCTGGCCCCGGCCCTCCCGCCACCCCGGCCCAGCCTCAGCCTGGCCTCCATGCCCCAGCGCCTCCGGCCTCCCAG
TACACGCCCATGCTCCCCAACACCTACCAGCCCCAGCCAGACAGCGTCTACCTGGTGCCCACTCCCAGCAAGGCTCAGCAAGGCCTCTAC
CAAGTCCCGGGTCCCAGCCCTCAGTTCCAGTCTCCCCCAGCCAAGCAGACATCCACCTTCTCGAAGCAGACACCCCATCACCCGTTTCCC
AGCCCGGCCACAGACCTGTACCAGGTGCCCCCAGGGCCTGGAGGCCCTGCCCAGGATATTTACCAGGTGCCACCTTCTGCCGGGATGGGG
CATGACATCTACCAGGTCCCCCCGTCCATGGACACACGCAGCTGGGAGGGCACGAAGCCCCCGGCAAAGGTGGTGGTGCCCACCCGCGTG
GGGCAGGGCTATGTATACGAGGCCGCCCAGCCGGAGCAGGACGAGTACGACATCCCGCGACACCTGCTGGCCCCGGGGCCACAGGACATC
TATGATGTGCCCCCGGTTCGGGGGCTGCTTCCCAGCCAGTATGGCCAGGAGGTGTATGACACACCCCCCATGGCTGTCAAGGGTCCCAAT
GGCCGAGACCCGTTGCTGGAGGTGTATGACGTGCCCCCCAGTGTGGAGAAGGGCCTGCCACCGTCCAACCACCACGCAGTCTACGACGTT
CCTCCATCGGTGAGCAAGGATGTGCCCGATGGCCCACTGCTGCGTGAGGAGACCTACGATGTGCCCCCCGCCTTCGCCAAGGCCAAGCCC
TTTGACCCGGCCCGCACCCCACTGGTACTGGCTGCGCCCCCTCCAGACTCCCCGCCGGCCGAGGACGTGTATGACGTGCCGCCCCCGGCT
CCTGACCTCTACGACGTGCCCCCTGGCTTGCGGCGGCCTGGCCCGGGCACCCTGTACGATGTGCCCCGTGAACGGGTGCTTCCTCCTGAG
GTGGCTGATGGTGGCGTGGTCGACAGTGGTGTGTATGCGGTGCCTCCCCCAGCTGAACGTGAAGCCCCGGCAGAGGGCAAGCGCCTGTCG
GCCTCCAGCACCGGCAGCACACGCAGCAGCCAGTCTGCGTCCTCCTTGGAGGTGGCAGGGCCGGGCCGGGAACCCCTGGAGCTGGAAGTT
GCTGTGGAGGCCCTGGCACGGCTGCAGCAGGGTGTGAGCGCCACCGTTGCCCACCTTCTGGACCTGGCAGGCAGCGCCGGTGCGACTGGG
AGCTGGCGTAGCCCCTCTGAGCCACAGGAGCCGCTGGTGCAGGACCTGCAGGCTGCTGTGGCCGCTGTCCAGAGTGCCGTCCACGAGCTG
TTGGAGTTTGCCCGCAGCGCGGTGGGCAATGCTGCCCACACATCTGACCGTGCCCTGCATGCCAAGCTTAGCCGGCAGCTGCAGAAGATG
GAGGACGTGCACCAGACGCTGGTGGCACATGGTCAGGCCCTCGACGCTGGCCGGGGAGGCTCTGGAGCCACCCTTGAGGACCTGGACCGG
CTGGTGGCCTGCTCGCGGGCTGTGCCCGAGGACGCCAAGCAGCTGGCCTCCTTCCTGCACGGCAATGCCTCACTGCTCTTCAGACGGACC
AAGGCCACTGCCCCGGGGCCTGAGGGGGGTGGCACCCTGCACCCCAACCCCACTGACAAGACCAGCAGCATCCAGTCACGACCCCTGCCC
TCACCCCCTAAGTTCACCTCCCAGGACTCGCCAGATGGGCAGTACGAGAACAGCGAGGGGGGCTGGATGGAGGACTATGACTACGTCCAC
CTACAGGGGAAGGAGGAGTTTGAGAAGACCCAGAAGGAGCTGCTGGAAAAGGGCAGCATCACGCGGCAGGGCAAGAGCCAGCTGGAGTTG
CAGCAGCTGAAGCAGTTTGAACGACTGGAACAGGAGGTGTCACGGCCCATAGACCACGACCTGGCCAACTGGACGCCAGCCCAACCCCTG
GCCCCGGGGCGAACAGGCGGCCTGGGGCCCTCGGACCGGCAGCTGCTGCTCTTCTACCTGGAGCAGTGTGAGGCCAACCTGACCACACTG
ACCAACGCCGTGGACGCCTTCTTTACCGCCGTGGCCACCAACCAGCCGCCCAAGATCTTTGTGGCGCACAGCAAGTTCGTCATCCTCAGC
GCCCACAAGCTGGTGTTCATCGGGGACACACTGTCACGGCAGGCCAAGGCTGCTGACGTGCGCAGCCAGGTGACCCACTACAGCAACCTG
CTGTGCGACCTCCTGCGCGGCATCGTGGCCACCACCAAGGCCGCTGCCTTGCAGTACCCATCGCCTTCCGCGGCCCAGGACATGGTGGAG
AGGGTCAAGGAGCTGGGCCACAGCACCCAGCAGTTCCGCCGCGTCCTAGGCCAGCTGGCAGCCGCCTGAGGGTGGTGACCCCAGGAGGGA
GGCAGGGGAGGGGTGCGGCGGTCCCAGCTCCCTGGCTCCCATGTCAAGAGTCGCTGTGCCACAGGCTTAGGGACAGGACCCCAGCTCTGC
GTCGGTCCTGGTGCCCTGGATGCCCAGGAATCTGTATATATTTATGGCCGGGCAGGGTGTGGGGCCATGCCTCCTCAGGAGCCGAAGCCC
AGGGGCCGGCCAGTGGCCTTCCCCAGCATGCACCACGGGCCCGGGTTGGGTCACCAGACGGGGCTGGAGTGTGAGGGTCCTGCAGCCTGC
AGGACCTCGTGCCACCCCGAGGGCTGAGCCTGGTCCCACGAGGGTGCCGTGTCCCCTGACAGGGCCAGTGCAGTTTGGTGTGTCCTCCGC
CTTACCAGGAGAAGAACCTGAAGAACTATTTTTCGTTATTGGTTTTCCAATCATTTGACTAAGAGTCTCCATTTAAATAAAGTTTTTAAA

>33240_33240_2_GLG1-BCAR1_GLG1_chr16_74640555_ENST00000422840_BCAR1_chr16_75276988_ENST00000162330_length(amino acids)=1012AA_BP=146
MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQQQQQQQQQQPQPPQP
PFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVRENVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQ
GLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLY
QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRV
GQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDV
PPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPE
VADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATG
SWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDR
LVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVH
LQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTL
TNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVE

--------------------------------------------------------------
>33240_33240_3_GLG1-BCAR1_GLG1_chr16_74640555_ENST00000447066_BCAR1_chr16_75276988_ENST00000162330_length(transcript)=3538nt_BP=456nt
GCTCGCCGCGGACTCAAGATGGCGGCGTGTGGACGTGTACGGAGGATGTTCCGCTTGTCGGCGGCGCTGCATCTGCTGCTGCTATTCGCG
GCCGGGGCCGAGAAACTCCCCGGCCAGGGCGTCCACAGCCAGGGCCAGGGTCCCGGGGCCAACTTTGTGTCCTTCGTAGGGCAGGCCGGA
GGCGGCGGCCCGGCGGGTCAGCAGCTGCCCCAGCTGCCTCAGTCATCGCAGCTTCAGCAGCAACAGCAGCAGCAGCAACAGCAACAGCAG
CCTCAGCCGCCGCAGCCGCCTTTCCCGGCGGGTGGGCCTCCGGCCCGGCGGGGAGGAGCGGGGGCTGGTGGGGGCTGGAAGCTGGCGGAG
GAAGAGTCCTGCAGGGAGGACGTGACCCGCGTGTGCCCTAAGCACACCTGGAGCAACAACCTGGCGGTGCTCGAGTGCCTGCAGGATGTG
AGGGAGAACGTGCTGGCCAAAGCGCTCTATGACAATGTGGCCGAGTCCCCGGATGAGCTCTCCTTCCGCAAGGGTGACATCATGACGGTG
CTGGAGCAGGACACGCAGGGCCTGGACGGCTGGTGGCTCTGCTCGCTGCATGGGCGCCAGGGCATCGTGCCTGGGAACCGCCTCAAGATC
TTGGTGGGCATGTATGATAAGAAGCCAGCAGGGCCTGGCCCCGGCCCTCCCGCCACCCCGGCCCAGCCTCAGCCTGGCCTCCATGCCCCA
GCGCCTCCGGCCTCCCAGTACACGCCCATGCTCCCCAACACCTACCAGCCCCAGCCAGACAGCGTCTACCTGGTGCCCACTCCCAGCAAG
GCTCAGCAAGGCCTCTACCAAGTCCCGGGTCCCAGCCCTCAGTTCCAGTCTCCCCCAGCCAAGCAGACATCCACCTTCTCGAAGCAGACA
CCCCATCACCCGTTTCCCAGCCCGGCCACAGACCTGTACCAGGTGCCCCCAGGGCCTGGAGGCCCTGCCCAGGATATTTACCAGGTGCCA
CCTTCTGCCGGGATGGGGCATGACATCTACCAGGTCCCCCCGTCCATGGACACACGCAGCTGGGAGGGCACGAAGCCCCCGGCAAAGGTG
GTGGTGCCCACCCGCGTGGGGCAGGGCTATGTATACGAGGCCGCCCAGCCGGAGCAGGACGAGTACGACATCCCGCGACACCTGCTGGCC
CCGGGGCCACAGGACATCTATGATGTGCCCCCGGTTCGGGGGCTGCTTCCCAGCCAGTATGGCCAGGAGGTGTATGACACACCCCCCATG
GCTGTCAAGGGTCCCAATGGCCGAGACCCGTTGCTGGAGGTGTATGACGTGCCCCCCAGTGTGGAGAAGGGCCTGCCACCGTCCAACCAC
CACGCAGTCTACGACGTTCCTCCATCGGTGAGCAAGGATGTGCCCGATGGCCCACTGCTGCGTGAGGAGACCTACGATGTGCCCCCCGCC
TTCGCCAAGGCCAAGCCCTTTGACCCGGCCCGCACCCCACTGGTACTGGCTGCGCCCCCTCCAGACTCCCCGCCGGCCGAGGACGTGTAT
GACGTGCCGCCCCCGGCTCCTGACCTCTACGACGTGCCCCCTGGCTTGCGGCGGCCTGGCCCGGGCACCCTGTACGATGTGCCCCGTGAA
CGGGTGCTTCCTCCTGAGGTGGCTGATGGTGGCGTGGTCGACAGTGGTGTGTATGCGGTGCCTCCCCCAGCTGAACGTGAAGCCCCGGCA
GAGGGCAAGCGCCTGTCGGCCTCCAGCACCGGCAGCACACGCAGCAGCCAGTCTGCGTCCTCCTTGGAGGTGGCAGGGCCGGGCCGGGAA
CCCCTGGAGCTGGAAGTTGCTGTGGAGGCCCTGGCACGGCTGCAGCAGGGTGTGAGCGCCACCGTTGCCCACCTTCTGGACCTGGCAGGC
AGCGCCGGTGCGACTGGGAGCTGGCGTAGCCCCTCTGAGCCACAGGAGCCGCTGGTGCAGGACCTGCAGGCTGCTGTGGCCGCTGTCCAG
AGTGCCGTCCACGAGCTGTTGGAGTTTGCCCGCAGCGCGGTGGGCAATGCTGCCCACACATCTGACCGTGCCCTGCATGCCAAGCTTAGC
CGGCAGCTGCAGAAGATGGAGGACGTGCACCAGACGCTGGTGGCACATGGTCAGGCCCTCGACGCTGGCCGGGGAGGCTCTGGAGCCACC
CTTGAGGACCTGGACCGGCTGGTGGCCTGCTCGCGGGCTGTGCCCGAGGACGCCAAGCAGCTGGCCTCCTTCCTGCACGGCAATGCCTCA
CTGCTCTTCAGACGGACCAAGGCCACTGCCCCGGGGCCTGAGGGGGGTGGCACCCTGCACCCCAACCCCACTGACAAGACCAGCAGCATC
CAGTCACGACCCCTGCCCTCACCCCCTAAGTTCACCTCCCAGGACTCGCCAGATGGGCAGTACGAGAACAGCGAGGGGGGCTGGATGGAG
GACTATGACTACGTCCACCTACAGGGGAAGGAGGAGTTTGAGAAGACCCAGAAGGAGCTGCTGGAAAAGGGCAGCATCACGCGGCAGGGC
AAGAGCCAGCTGGAGTTGCAGCAGCTGAAGCAGTTTGAACGACTGGAACAGGAGGTGTCACGGCCCATAGACCACGACCTGGCCAACTGG
ACGCCAGCCCAACCCCTGGCCCCGGGGCGAACAGGCGGCCTGGGGCCCTCGGACCGGCAGCTGCTGCTCTTCTACCTGGAGCAGTGTGAG
GCCAACCTGACCACACTGACCAACGCCGTGGACGCCTTCTTTACCGCCGTGGCCACCAACCAGCCGCCCAAGATCTTTGTGGCGCACAGC
AAGTTCGTCATCCTCAGCGCCCACAAGCTGGTGTTCATCGGGGACACACTGTCACGGCAGGCCAAGGCTGCTGACGTGCGCAGCCAGGTG
ACCCACTACAGCAACCTGCTGTGCGACCTCCTGCGCGGCATCGTGGCCACCACCAAGGCCGCTGCCTTGCAGTACCCATCGCCTTCCGCG
GCCCAGGACATGGTGGAGAGGGTCAAGGAGCTGGGCCACAGCACCCAGCAGTTCCGCCGCGTCCTAGGCCAGCTGGCAGCCGCCTGAGGG
TGGTGACCCCAGGAGGGAGGCAGGGGAGGGGTGCGGCGGTCCCAGCTCCCTGGCTCCCATGTCAAGAGTCGCTGTGCCACAGGCTTAGGG
ACAGGACCCCAGCTCTGCGTCGGTCCTGGTGCCCTGGATGCCCAGGAATCTGTATATATTTATGGCCGGGCAGGGTGTGGGGCCATGCCT
CCTCAGGAGCCGAAGCCCAGGGGCCGGCCAGTGGCCTTCCCCAGCATGCACCACGGGCCCGGGTTGGGTCACCAGACGGGGCTGGAGTGT
GAGGGTCCTGCAGCCTGCAGGACCTCGTGCCACCCCGAGGGCTGAGCCTGGTCCCACGAGGGTGCCGTGTCCCCTGACAGGGCCAGTGCA
GTTTGGTGTGTCCTCCGCCTTACCAGGAGAAGAACCTGAAGAACTATTTTTCGTTATTGGTTTTCCAATCATTTGACTAAGAGTCTCCAT

>33240_33240_3_GLG1-BCAR1_GLG1_chr16_74640555_ENST00000447066_BCAR1_chr16_75276988_ENST00000162330_length(amino acids)=1012AA_BP=146
MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQQQQQQQQQQPQPPQP
PFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVRENVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQ
GLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLY
QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRV
GQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDV
PPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPE
VADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATG
SWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDR
LVACSRAVPEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVH
LQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTL
TNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVE

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Fusion Gene PPI Analysis for GLG1-BCAR1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GLG1-BCAR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GLG1-BCAR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource