FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:GLIPR2-ZCCHC7 (FusionGDB2 ID:33299)

Fusion Gene Summary for GLIPR2-ZCCHC7

check button Fusion gene summary
Fusion gene informationFusion gene name: GLIPR2-ZCCHC7
Fusion gene ID: 33299
HgeneTgene
Gene symbol

GLIPR2

ZCCHC7

Gene ID

152007

84186

Gene nameGLI pathogenesis related 2zinc finger CCHC-type containing 7
SynonymsC9orf19|GAPR-1|GAPR1AIR1|HSPC086
Cytomap

9p13.3

9p13.2

Type of geneprotein-codingprotein-coding
DescriptionGolgi-associated plant pathogenesis-related protein 117kD fetal brain proteingliPR 2glioma pathogenesis-related protein 2golgi-associated PR-1 proteinzinc finger CCHC domain-containing protein 7TRAMP-like complex RNA-binding factor ZCCHC7zinc finger, CCHC domain containing 7
Modification date2020031320200320
UniProtAcc

Q9H4G4

Q8N3Z6

Ensembl transtripts involved in fusion geneENST00000377959, ENST00000377960, 
ENST00000396613, ENST00000474050, 
ENST00000461038, ENST00000534928, 
ENST00000322831, ENST00000336755, 
Fusion gene scores* DoF score6 X 5 X 3=9020 X 16 X 8=2560
# samples 622
** MAII scorelog2(6/90*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/2560*10)=-3.5405683813627
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GLIPR2 [Title/Abstract] AND ZCCHC7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZCCHC7(37126939)-GLIPR2(36162359), # samples:3
GLIPR2(36136788)-ZCCHC7(37302184), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGLIPR2

GO:0010634

positive regulation of epithelial cell migration

23516513

HgeneGLIPR2

GO:0010718

positive regulation of epithelial to mesenchymal transition

23516513

HgeneGLIPR2

GO:0070374

positive regulation of ERK1 and ERK2 cascade

23516513


check buttonFusion gene breakpoints across GLIPR2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZCCHC7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CR-7372GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+


Top

Fusion Gene ORF analysis for GLIPR2-ZCCHC7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000377959ENST00000461038GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-3UTRENST00000377960ENST00000461038GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-3UTRENST00000396613ENST00000461038GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-5UTRENST00000377959ENST00000534928GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-5UTRENST00000377960ENST00000534928GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-5UTRENST00000396613ENST00000534928GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-intronENST00000377959ENST00000322831GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-intronENST00000377960ENST00000322831GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
5CDS-intronENST00000396613ENST00000322831GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
In-frameENST00000377959ENST00000336755GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
In-frameENST00000377960ENST00000336755GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
In-frameENST00000396613ENST00000336755GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
intron-3CDSENST00000474050ENST00000336755GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
intron-3UTRENST00000474050ENST00000461038GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
intron-5UTRENST00000474050ENST00000534928GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+
intron-intronENST00000474050ENST00000322831GLIPR2chr9

36136788

+ZCCHC7chr9

37302184

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396613GLIPR2chr936136788+ENST00000336755ZCCHC7chr937302184+196057441078344
ENST00000377959GLIPR2chr936136788+ENST00000336755ZCCHC7chr937302184+195350371071344
ENST00000377960GLIPR2chr936136788+ENST00000336755ZCCHC7chr937302184+195047341068344

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396613ENST00000336755GLIPR2chr936136788+ZCCHC7chr937302184+0.001055820.9989442
ENST00000377959ENST00000336755GLIPR2chr936136788+ZCCHC7chr937302184+0.0010187030.9989813
ENST00000377960ENST00000336755GLIPR2chr936136788+ZCCHC7chr937302184+0.0010009910.99899906

Top

Fusion Genomic Features for GLIPR2-ZCCHC7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GLIPR2chr936136788+ZCCHC7chr937302184+1.19E-050.9999881
GLIPR2chr936136788+ZCCHC7chr937302184+1.19E-050.9999881

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for GLIPR2-ZCCHC7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:37126939/chr9:36162359)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GLIPR2

Q9H4G4

ZCCHC7

Q8N3Z6


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZCCHC7chr9:36136788chr9:37302184ENST0000033675519241_258203544.0Zinc fingerCCHC-type 1
TgeneZCCHC7chr9:36136788chr9:37302184ENST0000033675519263_280203544.0Zinc fingerCCHC-type 2
TgeneZCCHC7chr9:36136788chr9:37302184ENST0000033675519304_321203544.0Zinc fingerCCHC-type 3
TgeneZCCHC7chr9:36136788chr9:37302184ENST0000033675519348_365203544.0Zinc fingerCCHC-type 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGLIPR2chr9:36136788chr9:37302184ENST00000377960+1530_534155.0Coiled coilOntology_term=ECO:0000255
HgeneGLIPR2chr9:36136788chr9:37302184ENST00000377960+1514_1324155.0DomainNote=SCP


Top

Fusion Gene Sequence for GLIPR2-ZCCHC7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>33299_33299_1_GLIPR2-ZCCHC7_GLIPR2_chr9_36136788_ENST00000377959_ZCCHC7_chr9_37302184_ENST00000336755_length(transcript)=1953nt_BP=50nt
CGCAGCCGCGGGGAGCGAGGAGCGCGCGGAGCCGGCCATGGGCAAGTCAGGAGAAGATGGTATAAACTGGTCCATCAGTGACAAAGACAT
TGAGGCCCAGATAGCTAATAACCGAACACCTGGAAGATGGACCCAGCGGTACTATTCAGCCAACAAAAACATTATCTGTAGAAATTGTGA
CAAACGTGGTCATTTATCAAAAAACTGCCCCTTACCACGAAAAGTTCGTCGCTGCTTCCTGTGCTCCAGGAGAGGACATCTCCTGTATTC
CTGTCCAGCCCCCCTTTGCGAATACTGTCCTGTGCCTAAGATGTTGGACCACTCATGTCTTTTCAGACATTCCTGGGATAAACAGTGTGA
CCGATGTCATATGCTAGGCCACTATACAGATGCTTGCACAGAAATCTGGAGGCAGTATCACCTAACGACCAAACCTGGACCACCCAAAAA
GCCGAAGACCCCTTCAAGACCATCAGCCTTAGCATATTGCTATCACTGCGCGCAAAAAGGCCATTATGGACACGAATGTCCAGAAAGAGA
AGTGTATGACCCGTCTCCAGTATCTCCATTCATCTGCTACTATGATGACAAATATGAAATTCAGGAGAGAGAAAAGAGACTAAAACAAAA
AATAAAAGTACTCAAGAAAAATGGGGTTATCCCAGAGCCATCCAAGCTACCTTATATAAAAGCAGCAAATGAGAACCCCCACCATGATAT
AAGGAAGGGCCGTGCCTCATGGAAAAGCAACAGGTGGCCTCAAGAAAATAAAGAAACACAAAAAGAAATGAAGAACAAGAATAGAAACTG
GGAGAAGCACAGGAAGGCTGACAGACATCGTGAAGTGGATGAGGATTTTCCCAGGGGCCCCAAAACCTACTCTTCTCCTGGCAGTTTTAA
AACCCAGAAGCCTTCTAAGCCCTTTCACCGTTCATCACATTACCACACGTCAAGAGAAGACAAGTCTCCCAAGGAAGGCAAGAGGGGCAA
GCAGAAGAAAAAGGAGAGGTGCTGGGAAGATGATGACAATGATAACTTATTTCTTATTAAGCAGAGAAAAAAAAAGTCTTAAGCCGTCAG
GCAGCCTCTGATGTGGCTTTTCATTGTTCATTTGGCCTTTGTGTCTATAACCTTCTGGCACTGTGTTTATTATCTATGATTAAATAAAGT
GAGTTTTTGGTTTTGTTTTTTTAATTTCAGCCATTCCTAGAGTTACTGAATATCCATGGAGATCTCAATTCTCTGTGTCCAACAGGATAT
TAGGTAAGAAAGTACAAAGATAAACCTGGACTTCTCCTATTCCAATATGTCATCTTTACTCAGAATCCTAGGGATAGGTAGAAGAATTCA
TCTTTTCAAGAAAGTGTTTTAAAAATACTTTGGGAAAAAAACTGCATCAAAGGTAATTTATCCTCAAATTAAATCCTTGCAGGAAGAGAA
ATTAACACTAAGAAAAAGTCATCAATATTTTTCAACTTTTTTTTTTTTTTTTTTTACTTTGGAAAGGACAATAACTATAAACCTATATCC
AGATTTTCTTTCTGCTGAAGCTGTTGTCAGAATCTTCCTTTGGACAAAACATCACTAGCTGACTATAAAAACAAAAGTGTCATCATTGAA
GCCCTGAAGAGGCAGGGAATTGAGCTTCAGCAAAATACAGGAAAAGAACTATCCAGTATAAATGTCAGAAGACAGATTTCCTAAACAAGT
AAAAGAGACATCAAAAATTTTAACATAATCACAATGAAATCATTTTTTACCACTTTTACAGCGGTGTTTCAAGCGGACTGTCACTCAGAT
CTGCAGAGATGAATATTACTCAAAAAATTTTTTTGTTCTCTTGCATTTTTTTCAACTACCGCAAAGCTATACAGATTTTTTTGTACTTGT

>33299_33299_1_GLIPR2-ZCCHC7_GLIPR2_chr9_36136788_ENST00000377959_ZCCHC7_chr9_37302184_ENST00000336755_length(amino acids)=344AA_BP=4
MGKSGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVP
KMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVYDPSPVSPFIC
YYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREV

--------------------------------------------------------------
>33299_33299_2_GLIPR2-ZCCHC7_GLIPR2_chr9_36136788_ENST00000377960_ZCCHC7_chr9_37302184_ENST00000336755_length(transcript)=1950nt_BP=47nt
AGCCGCGGGGAGCGAGGAGCGCGCGGAGCCGGCCATGGGCAAGTCAGGAGAAGATGGTATAAACTGGTCCATCAGTGACAAAGACATTGA
GGCCCAGATAGCTAATAACCGAACACCTGGAAGATGGACCCAGCGGTACTATTCAGCCAACAAAAACATTATCTGTAGAAATTGTGACAA
ACGTGGTCATTTATCAAAAAACTGCCCCTTACCACGAAAAGTTCGTCGCTGCTTCCTGTGCTCCAGGAGAGGACATCTCCTGTATTCCTG
TCCAGCCCCCCTTTGCGAATACTGTCCTGTGCCTAAGATGTTGGACCACTCATGTCTTTTCAGACATTCCTGGGATAAACAGTGTGACCG
ATGTCATATGCTAGGCCACTATACAGATGCTTGCACAGAAATCTGGAGGCAGTATCACCTAACGACCAAACCTGGACCACCCAAAAAGCC
GAAGACCCCTTCAAGACCATCAGCCTTAGCATATTGCTATCACTGCGCGCAAAAAGGCCATTATGGACACGAATGTCCAGAAAGAGAAGT
GTATGACCCGTCTCCAGTATCTCCATTCATCTGCTACTATGATGACAAATATGAAATTCAGGAGAGAGAAAAGAGACTAAAACAAAAAAT
AAAAGTACTCAAGAAAAATGGGGTTATCCCAGAGCCATCCAAGCTACCTTATATAAAAGCAGCAAATGAGAACCCCCACCATGATATAAG
GAAGGGCCGTGCCTCATGGAAAAGCAACAGGTGGCCTCAAGAAAATAAAGAAACACAAAAAGAAATGAAGAACAAGAATAGAAACTGGGA
GAAGCACAGGAAGGCTGACAGACATCGTGAAGTGGATGAGGATTTTCCCAGGGGCCCCAAAACCTACTCTTCTCCTGGCAGTTTTAAAAC
CCAGAAGCCTTCTAAGCCCTTTCACCGTTCATCACATTACCACACGTCAAGAGAAGACAAGTCTCCCAAGGAAGGCAAGAGGGGCAAGCA
GAAGAAAAAGGAGAGGTGCTGGGAAGATGATGACAATGATAACTTATTTCTTATTAAGCAGAGAAAAAAAAAGTCTTAAGCCGTCAGGCA
GCCTCTGATGTGGCTTTTCATTGTTCATTTGGCCTTTGTGTCTATAACCTTCTGGCACTGTGTTTATTATCTATGATTAAATAAAGTGAG
TTTTTGGTTTTGTTTTTTTAATTTCAGCCATTCCTAGAGTTACTGAATATCCATGGAGATCTCAATTCTCTGTGTCCAACAGGATATTAG
GTAAGAAAGTACAAAGATAAACCTGGACTTCTCCTATTCCAATATGTCATCTTTACTCAGAATCCTAGGGATAGGTAGAAGAATTCATCT
TTTCAAGAAAGTGTTTTAAAAATACTTTGGGAAAAAAACTGCATCAAAGGTAATTTATCCTCAAATTAAATCCTTGCAGGAAGAGAAATT
AACACTAAGAAAAAGTCATCAATATTTTTCAACTTTTTTTTTTTTTTTTTTTACTTTGGAAAGGACAATAACTATAAACCTATATCCAGA
TTTTCTTTCTGCTGAAGCTGTTGTCAGAATCTTCCTTTGGACAAAACATCACTAGCTGACTATAAAAACAAAAGTGTCATCATTGAAGCC
CTGAAGAGGCAGGGAATTGAGCTTCAGCAAAATACAGGAAAAGAACTATCCAGTATAAATGTCAGAAGACAGATTTCCTAAACAAGTAAA
AGAGACATCAAAAATTTTAACATAATCACAATGAAATCATTTTTTACCACTTTTACAGCGGTGTTTCAAGCGGACTGTCACTCAGATCTG
CAGAGATGAATATTACTCAAAAAATTTTTTTGTTCTCTTGCATTTTTTTCAACTACCGCAAAGCTATACAGATTTTTTTGTACTTGTGGA

>33299_33299_2_GLIPR2-ZCCHC7_GLIPR2_chr9_36136788_ENST00000377960_ZCCHC7_chr9_37302184_ENST00000336755_length(amino acids)=344AA_BP=4
MGKSGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVP
KMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVYDPSPVSPFIC
YYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREV

--------------------------------------------------------------
>33299_33299_3_GLIPR2-ZCCHC7_GLIPR2_chr9_36136788_ENST00000396613_ZCCHC7_chr9_37302184_ENST00000336755_length(transcript)=1960nt_BP=57nt
AGTGCAGCGCAGCCGCGGGGAGCGAGGAGCGCGCGGAGCCGGCCATGGGCAAGTCAGGAGAAGATGGTATAAACTGGTCCATCAGTGACA
AAGACATTGAGGCCCAGATAGCTAATAACCGAACACCTGGAAGATGGACCCAGCGGTACTATTCAGCCAACAAAAACATTATCTGTAGAA
ATTGTGACAAACGTGGTCATTTATCAAAAAACTGCCCCTTACCACGAAAAGTTCGTCGCTGCTTCCTGTGCTCCAGGAGAGGACATCTCC
TGTATTCCTGTCCAGCCCCCCTTTGCGAATACTGTCCTGTGCCTAAGATGTTGGACCACTCATGTCTTTTCAGACATTCCTGGGATAAAC
AGTGTGACCGATGTCATATGCTAGGCCACTATACAGATGCTTGCACAGAAATCTGGAGGCAGTATCACCTAACGACCAAACCTGGACCAC
CCAAAAAGCCGAAGACCCCTTCAAGACCATCAGCCTTAGCATATTGCTATCACTGCGCGCAAAAAGGCCATTATGGACACGAATGTCCAG
AAAGAGAAGTGTATGACCCGTCTCCAGTATCTCCATTCATCTGCTACTATGATGACAAATATGAAATTCAGGAGAGAGAAAAGAGACTAA
AACAAAAAATAAAAGTACTCAAGAAAAATGGGGTTATCCCAGAGCCATCCAAGCTACCTTATATAAAAGCAGCAAATGAGAACCCCCACC
ATGATATAAGGAAGGGCCGTGCCTCATGGAAAAGCAACAGGTGGCCTCAAGAAAATAAAGAAACACAAAAAGAAATGAAGAACAAGAATA
GAAACTGGGAGAAGCACAGGAAGGCTGACAGACATCGTGAAGTGGATGAGGATTTTCCCAGGGGCCCCAAAACCTACTCTTCTCCTGGCA
GTTTTAAAACCCAGAAGCCTTCTAAGCCCTTTCACCGTTCATCACATTACCACACGTCAAGAGAAGACAAGTCTCCCAAGGAAGGCAAGA
GGGGCAAGCAGAAGAAAAAGGAGAGGTGCTGGGAAGATGATGACAATGATAACTTATTTCTTATTAAGCAGAGAAAAAAAAAGTCTTAAG
CCGTCAGGCAGCCTCTGATGTGGCTTTTCATTGTTCATTTGGCCTTTGTGTCTATAACCTTCTGGCACTGTGTTTATTATCTATGATTAA
ATAAAGTGAGTTTTTGGTTTTGTTTTTTTAATTTCAGCCATTCCTAGAGTTACTGAATATCCATGGAGATCTCAATTCTCTGTGTCCAAC
AGGATATTAGGTAAGAAAGTACAAAGATAAACCTGGACTTCTCCTATTCCAATATGTCATCTTTACTCAGAATCCTAGGGATAGGTAGAA
GAATTCATCTTTTCAAGAAAGTGTTTTAAAAATACTTTGGGAAAAAAACTGCATCAAAGGTAATTTATCCTCAAATTAAATCCTTGCAGG
AAGAGAAATTAACACTAAGAAAAAGTCATCAATATTTTTCAACTTTTTTTTTTTTTTTTTTTACTTTGGAAAGGACAATAACTATAAACC
TATATCCAGATTTTCTTTCTGCTGAAGCTGTTGTCAGAATCTTCCTTTGGACAAAACATCACTAGCTGACTATAAAAACAAAAGTGTCAT
CATTGAAGCCCTGAAGAGGCAGGGAATTGAGCTTCAGCAAAATACAGGAAAAGAACTATCCAGTATAAATGTCAGAAGACAGATTTCCTA
AACAAGTAAAAGAGACATCAAAAATTTTAACATAATCACAATGAAATCATTTTTTACCACTTTTACAGCGGTGTTTCAAGCGGACTGTCA
CTCAGATCTGCAGAGATGAATATTACTCAAAAAATTTTTTTGTTCTCTTGCATTTTTTTCAACTACCGCAAAGCTATACAGATTTTTTTG

>33299_33299_3_GLIPR2-ZCCHC7_GLIPR2_chr9_36136788_ENST00000396613_ZCCHC7_chr9_37302184_ENST00000336755_length(amino acids)=344AA_BP=4
MGKSGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVP
KMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVYDPSPVSPFIC
YYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for GLIPR2-ZCCHC7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneGLIPR2chr9:36136788chr9:37302184ENST00000377960+1591_984.333333333333333155.0CAV1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for GLIPR2-ZCCHC7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for GLIPR2-ZCCHC7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource